"Checked"	"Master"	"Accession"	"Description"	"Coverage [%]"	"# Peptides"	"# PSMs"	"# Unique Peptides"	"# AAs"	"MW [kDa]"	"calc. pI"	"Score MS Amanda 2.0: MS Amanda 2.0"	"Score Sequest HT: Sequest HT"	"# Peptides (by Search Engine): MS Amanda 2.0"	"# Peptides (by Search Engine): Sequest HT"	"Biological Process"	"Cellular Component"	"Molecular Function"	"Pfam IDs"	"Entrez Gene ID"	"Ensembl Gene ID"	"Gene Symbol"	"Gene ID"	"WikiPathways"	"Reactome Pathways"	"# Protein Pathway Groups"	"# Razor Peptides"	"Abundances (Grouped): 126"	"Abundances (Grouped): 127N"	"Abundances (Grouped): 127C"	"Abundances (Grouped): 128N"	"Abundances (Grouped): 128C"	"Abundances (Grouped): 129N"	"Abundances (Grouped): 129C"	"Abundances (Grouped): 130N"	"Abundances (Grouped): 130C"	"Abundances (Grouped): 131N"	"Abundances (Grouped): 131C"	"Abundances (Grouped) CV [%]: 126"	"Abundances (Grouped) CV [%]: 127N"	"Abundances (Grouped) CV [%]: 127C"	"Abundances (Grouped) CV [%]: 128N"	"Abundances (Grouped) CV [%]: 128C"	"Abundances (Grouped) CV [%]: 129N"	"Abundances (Grouped) CV [%]: 129C"	"Abundances (Grouped) CV [%]: 130N"	"Abundances (Grouped) CV [%]: 130C"	"Abundances (Grouped) CV [%]: 131N"	"Abundances (Grouped) CV [%]: 131C"	"Found in Sample: F10: 126, Sample"	"Found in Sample: F10: 127N, Sample"	"Found in Sample: F10: 127C, Sample"	"Found in Sample: F10: 128N, Sample"	"Found in Sample: F10: 128C, Sample"	"Found in Sample: F10: 129N, Sample"	"Found in Sample: F10: 129C, Sample"	"Found in Sample: F10: 130N, Sample"	"Found in Sample: F10: 130C, Sample"	"Found in Sample: F10: 131N, Sample"	"Found in Sample: F10: 131C, Sample"	"# Protein Groups"	"Modifications"
"False"	"IsMasterProtein"	"Q13813"	"Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3"	"48"	"112"	"236"	"112"	"2472"	"284.4"	"5.35"	"43610.24"	"438.03"	"93"	"102"	"cell organization and biogenesis"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00018, Pf00435, Pf08726, Pf13499"	"6709"	"ENSG00000197694"	"SPTAN1"	"hsa:6709; Q13186; Q13813; Q15324; Q16606; Q59EF1; Q5VXV5; Q5VXV6; Q7Z6M5; Q9P0V0"	"Fas ligand pathway and stress induction of heat shock proteins"	"Neutrophil degranulation; RAF/MAP kinase cascade; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Interaction between L1 and Ankyrins; RHOV GTPase cycle; COPI-mediated anterograde transport; RHOU GTPase cycle; Nephrin family interactions; NCAM signaling for neurite out-growth; Caspase-mediated cleavage of cytoskeletal proteins"	"12"	"0"	"12410.8"	"7366.6"	"10894.8"	"9652.4"	"10507.7"	"11569.0"	"21917.3"	"20642.6"	"15264.7"	"25840.7"	"37838.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08670"	"Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4"	"68"	"41"	"178"	"38"	"466"	"53.6"	"5.12"	"37812.50"	"274.25"	"38"	"37"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00038, Pf04732"	"7431"	"ENSG00000026025"	"VIM"	"B0YJC2; D3DRU4; hsa:7431; P08670; Q15867; Q15868; Q15869; Q548L2; Q6LER9; Q8N850; Q96ML2; Q9NTM3"	"Allograft rejection; Spinal cord injury; Primary focal segmental glomerulosclerosis (FSGS); Mammary gland development pathway - Puberty (Stage 2 of 4); Apoptosis-related network due to altered Notch3 in ovarian cancer; Striated muscle contraction pathway; TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition; Ciliary landscape; Burn wound healing; CCL18 signaling pathway; TROP2 regulatory signaling; CKAP4 signaling pathway map; A network map of Macrophage-stimulating protein (MSP) signaling; T-cell receptor signaling pathway"	"Aggrephagy; Interleukin-4 and Interleukin-13 signaling; Chaperone Mediated Autophagy; Late endosomal microautophagy; Striated Muscle Contraction; RHOBTB1 GTPase cycle; Caspase-mediated cleavage of cytoskeletal proteins"	"21"	"5"	"10284.7"	"7928.4"	"9624.2"	"10100.9"	"9773.4"	"12427.0"	"12188.1"	"11289.3"	"9346.7"	"13840.8"	"18500.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q08211"	"ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4"	"41"	"46"	"134"	"46"	"1270"	"140.9"	"6.84"	"25090.60"	"261.66"	"38"	"40"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;cytoskeleton;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00035, Pf00270, Pf00271, Pf04408, Pf07717"	"1660"	"ENSG00000135829"	"DHX9"	"B2RNV4; hsa:1660; Q05CI5; Q08211; Q12803; Q32Q22; Q5VY62; Q6PD69; Q99556"	"MECP2 and associated Rett syndrome; mRNA processing"	"mRNA Splicing - Major Pathway; RIP-mediated NFkB activation via ZBP1; DEx/H-box helicases activate type I IFN and inflammatory cytokines production"	"5"	"0"	"3426.8"	"2519.0"	"3267.4"	"3035.7"	"3326.0"	"3338.0"	"9250.2"	"11429.5"	"8606.5"	"11283.4"	"13735.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01082"	"Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2"	"28"	"63"	"138"	"57"	"2364"	"274.4"	"5.57"	"26570.23"	"244.30"	"59"	"60"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00169, Pf00307, Pf00435"	"6711"	"ENSG00000115306"	"SPTBN1"	"B2RP63; hsa:6711; O60837; Q01082; Q16057; Q53R99; Q59ER3; Q8IX99"	"Sudden infant death syndrome (SIDS) susceptibility pathways"	"RHOV GTPase cycle; RHOU GTPase cycle; RAF/MAP kinase cascade; NCAM signaling for neurite out-growth; Signaling by FLT3 fusion proteins; COPI-mediated anterograde transport; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Nephrin family interactions; Interaction between L1 and Ankyrins"	"11"	"7"	"4622.1"	"3012.3"	"4353.5"	"3977.3"	"4509.0"	"4689.3"	"9756.9"	"9292.9"	"7146.0"	"11999.9"	"17191.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22626"	"Heterogeneous nuclear ribonucleoproteins A2/B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2"	"83"	"24"	"114"	"21"	"353"	"37.4"	"8.95"	"17982.80"	"243.92"	"19"	"21"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"3181"	"ENSG00000122566"	"HNRNPA2B1"	"A0A024RA27; A0A024RA61; A8K064; hsa:3181; P22626; P22627; Q9UC98; Q9UDJ2"	"mRNA processing"	"Processing of Capped Intron-Containing Pre-mRNA; mRNA Splicing - Major Pathway; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"4"	"3"	"9217.6"	"6389.1"	"7115.6"	"6359.6"	"6991.8"	"7479.7"	"14937.3"	"13688.9"	"11287.1"	"16841.6"	"20284.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61978"	"Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1"	"57"	"27"	"124"	"27"	"463"	"50.9"	"5.54"	"23291.99"	"227.24"	"23"	"26"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf08067"	"3190"	"ENSG00000165119"	"HNRNPK"	"hsa:3190; P61978; Q07244; Q15671; Q59F98; Q5T6W4; Q60577; Q6IBN1; Q922Y7; Q96J62"	"mRNA processing; lncRNA in canonical Wnt signaling and colorectal cancer"	"mRNA Splicing - Major Pathway; HCMV Late Events; SUMOylation of RNA binding proteins; Processing of Capped Intron-Containing Pre-mRNA"	"6"	"0"	"10836.1"	"4852.1"	"6463.7"	"8013.3"	"6454.3"	"9263.5"	"16805.1"	"16068.7"	"12746.5"	"13704.8"	"13379.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23284"	"Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2"	"71"	"25"	"120"	"25"	"216"	"23.7"	"9.41"	"20184.73"	"227.11"	"18"	"24"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00160"	"5479"	"ENSG00000166794"	"PPIB"	"A8K534; hsa:5479; P23284; Q6IBH5; Q9BVK5"	"Prolactin signaling pathway; Type I collagen synthesis in the context of osteogenesis imperfecta"	"Collagen biosynthesis and modifying enzymes; SARS-CoV-1 activates/modulates innate immune responses"	"4"	"0"	"1123.1"	"621.1"	"1119.9"	"1080.0"	"1222.1"	"1168.2"	"6753.4"	"11107.2"	"17731.4"	"28010.1"	"47797.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11142"	"Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1"	"59"	"36"	"115"	"22"	"646"	"70.9"	"5.52"	"20827.54"	"200.10"	"32"	"35"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00012"	"3312"	"ENSG00000109971"	"HSPA8"	"hsa:3312; P11142; Q9H3R6"	"Parkin-ubiquitin proteasomal system pathway; MAPK signaling pathway; Exercise-induced circadian regulation; Measles virus infection; Opioid receptor pathways; Extrafollicular and follicular B cell activation by SARS-CoV-2; 1p36 copy number variation syndrome"	"AUF1 (hnRNP D0) binds and destabilizes mRNA; Neutrophil degranulation; mRNA Splicing - Major Pathway; Golgi Associated Vesicle Biogenesis; Clathrin-mediated endocytosis; Late endosomal microautophagy; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Regulation of HSF1-mediated heat shock response; Lysosome Vesicle Biogenesis; CHL1 interactions; Interleukin-4 and Interleukin-13 signaling; GABA synthesis, release, reuptake and degradation; Lipophagy; Chaperone Mediated Autophagy; Protein methylation; Attenuation phase"	"24"	"18"	"10071.1"	"5298.3"	"8550.0"	"8462.4"	"8311.5"	"8903.0"	"13834.9"	"12802.8"	"9357.9"	"13965.0"	"20918.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63010"	"AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1"	"39"	"38"	"90"	"21"	"937"	"104.5"	"5.38"	"13311.18"	"192.06"	"27"	"35"	"transport;developmental processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01602, Pf02883, Pf09066"	"163"	"ENSG00000006125"	"AP2B1"	"A6NJP3; hsa:163; P21851; P63010; Q7Z451; Q96J19"	"Synaptic vesicle pathway; GABA receptor signaling; EGF/EGFR signaling pathway; Fragile X syndrome; mBDNF and proBDNF regulation of GABA neurotransmission; Markers of kidney cell lineage; 17q12 copy number variation syndrome"	"Cargo recognition for clathrin-mediated endocytosis; VLDLR internalisation and degradation; WNT5A-dependent internalization of FZD4; MHC class II antigen presentation; Recycling pathway of L1; Retrograde neurotrophin signalling; Potential therapeutics for SARS; EPH-ephrin mediated repulsion of cells; LDL clearance; Nef Mediated CD4 Down-regulation; Nef Mediated CD8 Down-regulation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2"	"20"	"18"	"976.2"	"588.7"	"983.9"	"911.4"	"1102.2"	"1143.1"	"3311.7"	"6124.4"	"10096.4"	"20202.4"	"34562.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04264"	"Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6"	"44"	"37"	"109"	"29"	"644"	"66.0"	"8.12"	"20751.47"	"191.52"	"33"	"33"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"bone, tooth or skin structural activity;other molecular function"	"Pf00038, Pf16208, Pf16210"	"3848"	"ENSG00000167768"	"KRT1"	"B2RA01; hsa:3848; P04264; P85925; P86104; Q14720; Q6GSJ0; Q9H298"	"Corticotropin-releasing hormone signaling pathway"	"Formation of the cornified envelope; Neutrophil degranulation"	"4"	"8"	"3020.4"	"830.7"	"38788.9"	"1963.6"	"866.3"	"4134.6"	"7394.7"	"6705.7"	"4330.3"	"10506.7"	"6676.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20700"	"Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2"	"54"	"37"	"109"	"32"	"586"	"66.4"	"5.16"	"19796.27"	"182.02"	"35"	"34"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytoskeleton;nucleus"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00038, Pf00932"	"4001"	"ENSG00000113368"	"LMNB1"	"B2R6J6; hsa:4001; P20700; Q3SYN7; Q96EI6"	"Fas ligand pathway and stress induction of heat shock proteins; Familial partial lipodystrophy; Progeria-associated lipodystrophy; Acquired partial lipodystrophy / Barraquer-Simons syndrome"	"Meiotic synapsis; RHOD GTPase cycle; RHOF GTPase cycle; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models; Initiation of Nuclear Envelope (NE) Reformation; Depolymerization of the Nuclear Lamina; Breakdown of the nuclear lamina; Formation of Senescence-Associated Heterochromatin Foci (SAHF)"	"14"	"6"	"7752.1"	"4630.4"	"6060.6"	"5495.9"	"6201.1"	"7044.4"	"11794.9"	"10860.2"	"8179.4"	"12833.6"	"17495.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00159"	"Unconventional myosin-Ic OS=Homo sapiens OX=9606 GN=MYO1C PE=1 SV=4"	"45"	"43"	"100"	"42"	"1063"	"121.6"	"9.41"	"18232.54"	"178.91"	"38"	"39"	"cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00063, Pf00612, Pf06017"	"4641"	"ENSG00000197879"	"MYO1C"	"hsa:4641; O00159; Q4LE56; Q6NVJ7; Q86Y95"	"VEGFA-VEGFR2 signaling; Insulin signaling; 10q11.21q11.23 copy number variation syndrome"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea"	"8"	"1"	"1557.6"	"1000.7"	"1651.7"	"1568.0"	"1672.3"	"1988.4"	"4828.7"	"7130.7"	"7921.5"	"16435.9"	"26729.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04406"	"Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3"	"64"	"21"	"72"	"21"	"335"	"36.0"	"8.46"	"10282.42"	"171.08"	"14"	"20"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00044, Pf02800"	"2597"	"ENSG00000111640"	"GAPDH"	"E7EUT4; hsa:2597; P00354; P04406; Q53X65"	"Cori cycle; Alzheimer's disease and miRNA effects; HIF1A and PPARG regulation of glycolysis; VEGFA-VEGFR2 signaling; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; 7q11.23 copy number variation syndrome; Glycolysis in senescence; Alzheimer's disease; Sildenafil treatment; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Glycolysis; Gluconeogenesis"	"16"	"0"	"2238.7"	"1428.9"	"2333.1"	"1813.8"	"2341.4"	"2043.6"	"7388.7"	"7239.1"	"5689.8"	"8174.3"	"11937.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P0DMV9"	"Heat shock 70 kDa protein 1B OS=Homo sapiens OX=9606 GN=HSPA1B PE=1 SV=1"	"60"	"34"	"84"	"28"	"641"	"70.0"	"5.66"	"14806.59"	"166.56"	"26"	"32"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00012"	"3303; 3304"	"ENSG00000204388; ENSG00000212866; ENSG00000224501; ENSG00000231555; ENSG00000232804"	"HSPA1B"	"B4E3B6; hsa:3303; hsa:3304; P08107; P0DMV9; P19790; Q5JQI4; Q5SP17; Q9UQL9; Q9UQM0"	"Apoptosis modulation and signaling; Parkin-ubiquitin proteasomal system pathway; MAPK signaling pathway; Apoptosis modulation by HSP70; VEGFA-VEGFR2 signaling; Measles virus infection; CKAP4 signaling pathway map"	"Neutrophil degranulation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Regulation of HSF1-mediated heat shock response; Attenuation phase"	"12"	"0"	"4788.4"	"2437.5"	"3936.0"	"4710.1"	"4278.3"	"4517.1"	"7153.6"	"6373.2"	"4420.2"	"7083.3"	"10185.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92841"	"Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2"	"43"	"30"	"99"	"23"	"729"	"80.2"	"8.27"	"18445.19"	"163.11"	"30"	"28"	"RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"10521"	"ENSG00000100201"	"DDX17"	"B1AHM0; H3BLZ8; hsa:10521; Q69YT1; Q6ICD6; Q92841"	"Novel intracellular components of RIG-I-like receptor pathway"	"SUMOylation of transcription cofactors"	"2"	"9"	"3450.4"	"2242.7"	"2968.8"	"2477.4"	"3082.0"	"2996.5"	"7774.9"	"7198.3"	"5454.6"	"8367.5"	"9820.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75643"	"U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2"	"26"	"46"	"97"	"46"	"2136"	"244.4"	"6.06"	"17561.52"	"160.52"	"43"	"43"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00270, Pf00271, Pf02889, Pf18149"	"23020"	"ENSG00000144028"	"SNRNP200"	"hsa:23020; O75643; O94884; Q6NZY0; Q6PX59; Q8NBE6; Q96IF2; Q9H7S0"	"2q11.2 copy number variation syndrome"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"0"	"3303.7"	"2129.7"	"3079.3"	"2533.6"	"3091.5"	"3044.4"	"6198.2"	"5653.3"	"4578.5"	"7472.2"	"9928.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7KZF4"	"Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1"	"42"	"34"	"80"	"34"	"910"	"101.9"	"7.17"	"13303.71"	"148.16"	"27"	"34"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00565, Pf00567"	"27044"	"ENSG00000197157"	"SND1"	"hsa:27044; Q13122; Q7KZF4; Q96AG0"	"VEGFA-VEGFR2 signaling"	"Signaling by BRAF and RAF1 fusions"	"2"	"0"	"1912.2"	"1359.7"	"1822.9"	"1594.3"	"1890.7"	"1806.7"	"8919.7"	"8628.4"	"6911.1"	"9145.0"	"11760.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P2Q9"	"Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2"	"22"	"45"	"85"	"45"	"2335"	"273.4"	"8.84"	"14977.77"	"143.13"	"39"	"40"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01398, Pf08082, Pf08083, Pf08084, Pf10596, Pf10597, Pf10598, Pf12134"	"10594"	"ENSG00000174231; ENSG00000274442"	"PRPF8"	"hsa:10594; O14547; O75965; Q6P2Q9"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"0"	"3913.2"	"2580.5"	"3758.2"	"2773.3"	"3479.6"	"3364.0"	"7438.2"	"6671.0"	"5232.9"	"9333.0"	"12174.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P02545"	"Prelamin-A/C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1"	"42"	"34"	"88"	"33"	"664"	"74.1"	"7.02"	"16452.05"	"137.05"	"33"	"33"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00038, Pf00932"	"4000"	"ENSG00000160789"	"LMNA"	"B4DI32; D3DVB0; D6RAQ3; E7EUI9; hsa:4000; P02545; P02546; Q5I6Y4; Q5I6Y6; Q5TCJ2; Q5TCJ3; Q6UYC3; Q969I8; Q96JA2"	"Arrhythmogenic right ventricular cardiomyopathy; Adipogenesis; Fas ligand pathway and stress induction of heat shock proteins; Lamin A-processing pathway; Nephrotic syndrome; Influence of laminopathies on Wnt signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies; Familial partial lipodystrophy; Progeria-associated lipodystrophy; Acquired partial lipodystrophy / Barraquer-Simons syndrome; Primary ovarian insufficiency"	"XBP1(S) activates chaperone genes; Signaling by BRAF and RAF1 fusions"	"13"	"0"	"3405.0"	"1943.3"	"3001.7"	"2998.7"	"3059.8"	"3573.6"	"12184.5"	"11928.8"	"8488.7"	"12505.3"	"17114.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00839"	"Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6"	"44"	"35"	"85"	"34"	"825"	"90.5"	"6.00"	"15705.84"	"137.02"	"25"	"29"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00622, Pf02037, Pf13671"	"3192"	"ENSG00000153187"	"HNRNPU"	"hsa:3192; O75507; Q00839; Q8N174; Q96HY9; Q9BQ09"	"mRNA processing; lncRNA in canonical Wnt signaling and colorectal cancer"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"4"	"1"	"7689.3"	"4853.6"	"6359.6"	"5222.5"	"6268.5"	"7322.3"	"12264.2"	"9629.6"	"6543.8"	"12808.9"	"17232.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43491"	"Band 4.1-like protein 2 OS=Homo sapiens OX=9606 GN=EPB41L2 PE=1 SV=1"	"41"	"32"	"67"	"30"	"1005"	"112.5"	"5.44"	"12958.78"	"136.57"	"26"	"29"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf04382, Pf05902, Pf08736, Pf09379, Pf09380"	"2037"	"ENSG00000079819"	"EPB41L2"	"B4DHI8; E9PPD9; hsa:2037; O43491; Q5T4F0; Q68DV2"	"Splicing factor NOVA regulated synaptic proteins"	"Neurexins and neuroligins"	"2"	"2"	"3143.4"	"1643.3"	"2328.3"	"2907.4"	"2535.7"	"3488.5"	"6808.1"	"6010.4"	"5265.2"	"11181.5"	"17479.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43390"	"Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1"	"49"	"30"	"69"	"22"	"633"	"70.9"	"8.13"	"11343.63"	"135.11"	"24"	"28"	"RNA metabolism OR transcription;other metabolic processes"	"ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf18360"	"10236"	"ENSG00000125944; ENSG00000282958"	"HNRNPR"	"hsa:10236; O43390; Q2L7G6; Q5TEH1; Q9BV64; S4R3J4"	"mRNA processing"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"3"	"9"	"3262.1"	"2418.9"	"3262.0"	"3024.3"	"3240.2"	"3372.1"	"6149.5"	"5371.6"	"3966.7"	"6782.3"	"8206.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7KZ85"	"Transcription elongation factor SPT6 OS=Homo sapiens OX=9606 GN=SUPT6H PE=1 SV=2"	"28"	"40"	"74"	"40"	"1726"	"198.9"	"4.91"	"13310.59"	"134.92"	"33"	"34"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00575, Pf14632, Pf14633, Pf14635, Pf14639, Pf14641, Pf17674"	"6830"	"ENSG00000109111"	"SUPT6H"	"A7E2B4; hsa:6830; Q15737; Q6GMQ4; Q7KYW9; Q7KZ85; Q7LDK4; Q8N526; Q92775; Q96AH3; Q9BTH9; Q9BTI2"	""	"Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events"	"3"	"0"	"3283.6"	"1902.3"	"2718.5"	"2593.4"	"2539.4"	"2981.2"	"6456.2"	"6135.5"	"4857.2"	"6606.0"	"8606.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35637"	"RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1"	"20"	"14"	"72"	"10"	"526"	"53.4"	"9.36"	"15704.57"	"133.51"	"11"	"10"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00641"	"2521"	"ENSG00000089280"	"FUS"	"hsa:2521; P35637; Q9H4A8"	"MECP2 and associated Rett syndrome; mRNA processing"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"4"	"5"	"4724.6"	"3456.9"	"4024.1"	"3409.7"	"3764.3"	"3432.0"	"8771.5"	"8712.4"	"7934.5"	"8904.5"	"8991.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P54577"	"Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4"	"66"	"35"	"75"	"35"	"528"	"59.1"	"7.05"	"13743.47"	"133.21"	"30"	"31"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00579, Pf01588"	"8565"	"ENSG00000134684"	"YARS1"	"B3KWK4; D3DPQ4; hsa:8565; O43276; P54577; Q53EN1"	"Nephrotic syndrome"	"Cytosolic tRNA aminoacylation"	"2"	"0"	"1658.1"	"892.2"	"1449.2"	"1657.3"	"1632.3"	"2041.2"	"6850.4"	"7594.2"	"8335.7"	"17209.8"	"31038.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12906"	"Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3"	"34"	"26"	"66"	"23"	"894"	"95.3"	"8.76"	"11986.51"	"125.67"	"22"	"25"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00035, Pf07528"	"3609"	"ENSG00000129351"	"ILF3"	"A8K6F2; G5E9M5; hsa:3609; O43409; Q12906; Q6P1X1; Q86XY7; Q99544; Q99545; Q9BZH4; Q9BZH5; Q9NQ95; Q9NQ96; Q9NQ97; Q9NQ98; Q9NQ99; Q9NQA0; Q9NQA1; Q9NQA2; Q9NRN2; Q9NRN3; Q9NRN4; Q9UMZ9; Q9UN00; Q9UN84; Q9UNA2"	""	"Regulation of CDH11 gene transcription"	"1"	"4"	"2547.8"	"1758.9"	"2392.1"	"2115.3"	"2281.0"	"2486.3"	"6213.2"	"5587.2"	"4017.5"	"6640.5"	"8045.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14103"	"Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1"	"40"	"21"	"68"	"18"	"355"	"38.4"	"7.81"	"12569.82"	"125.34"	"19"	"20"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08143"	"3184"	"ENSG00000138668"	"HNRNPD"	"A8K9J2; hsa:3184; P07029; Q01858; Q14100; Q14101; Q14102; Q14103; Q4W5A1; Q9UCE8; Q9UCE9"	"mRNA processing"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"3"	"5"	"4440.3"	"3072.3"	"3930.4"	"3881.2"	"3855.7"	"4321.0"	"9417.3"	"8535.7"	"6494.9"	"9567.2"	"12440.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94973"	"AP-2 complex subunit alpha-2 OS=Homo sapiens OX=9606 GN=AP2A2 PE=1 SV=2"	"31"	"27"	"68"	"20"	"939"	"103.9"	"6.96"	"10950.83"	"124.56"	"20"	"26"	"transport"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01602, Pf02296, Pf02883"	"161"	"ENSG00000183020"	"AP2A2"	"hsa:161; O75403; O94973; Q53ET1; Q96SI8"	"Synaptic vesicle pathway; GABA receptor signaling; mBDNF and proBDNF regulation of GABA neurotransmission"	"Potential therapeutics for SARS; Recycling pathway of L1; MHC class II antigen presentation; Neutrophil degranulation; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; LDL clearance; Nef Mediated CD4 Down-regulation; Retrograde neurotrophin signalling; Nef Mediated CD8 Down-regulation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation"	"17"	"8"	"712.0"	"472.4"	"809.7"	"657.8"	"767.8"	"860.7"	"2306.5"	"4291.1"	"7274.6"	"14099.8"	"21638.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23246"	"Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2"	"34"	"22"	"72"	"21"	"707"	"76.1"	"9.44"	"13898.15"	"123.19"	"19"	"20"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08075"	"6421"	"ENSG00000116560"	"SFPQ"	"hsa:6421; P23246; P30808; Q5SZ71"	"mRNA processing; Type 2 papillary renal cell carcinoma"	"Suppression of apoptosis; PTK6 Regulates Proteins Involved in RNA Processing"	"4"	"1"	"2988.0"	"2010.3"	"2556.6"	"2133.9"	"2515.3"	"2270.1"	"7610.2"	"7659.0"	"6051.8"	"7783.2"	"9073.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P38646"	"Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2"	"48"	"30"	"65"	"29"	"679"	"73.6"	"6.16"	"11848.26"	"122.19"	"27"	"26"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00012"	"3313"	"ENSG00000113013"	"HSPA9"	"B2RCM1; hsa:3313; P30036; P31932; P38646; Q1HB43; Q53H23; Q6GU03; Q9BWB7; Q9UC56"	"Parkin-ubiquitin proteasomal system pathway; Iron-sulfur cluster biogenesis"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Mitochondrial protein import; Regulation of HSF1-mediated heat shock response; Cristae formation"	"6"	"0"	"5899.9"	"3110.1"	"4284.8"	"4980.7"	"4266.3"	"5028.7"	"6253.7"	"6155.5"	"4808.6"	"6887.4"	"10111.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55072"	"Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4"	"47"	"32"	"71"	"32"	"806"	"89.3"	"5.26"	"14080.50"	"121.64"	"29"	"28"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"non-structural extracellular;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00004, Pf02359, Pf02933, Pf09336, Pf17862"	"7415"	"ENSG00000165280"	"VCP"	"B2R5T8; hsa:7415; P55072; Q0V924; Q2TAI5; Q969G7; Q9UCD5"	"Alstrom syndrome; Clock-controlled autophagy in bone metabolism"	"Neutrophil degranulation; ABC-family proteins mediated transport; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Defective CFTR causes cystic fibrosis; Neddylation; KEAP1-NFE2L2 pathway; E3 ubiquitin ligases ubiquitinate target proteins; Aggrephagy; Attachment and Entry; Attachment and Entry; Ovarian tumor domain proteases; Josephin domain DUBs; Protein methylation; RHOH GTPase cycle; HSF1 activation; Translesion Synthesis by POLH; N-glycan trimming in the ER and Calnexin/Calreticulin cycle"	"20"	"0"	"4657.1"	"3014.7"	"4397.2"	"3778.7"	"3860.4"	"4083.8"	"5656.9"	"5310.8"	"4137.7"	"6234.4"	"8611.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07910"	"Heterogeneous nuclear ribonucleoproteins C1/C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4"	"37"	"19"	"83"	"19"	"306"	"33.7"	"5.08"	"18345.01"	"121.30"	"19"	"16"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"3183"	"ENSG00000092199"	"HNRNPC"	"D3DS19; D3DS22; hsa:3183; P07910; P22628; Q53EX2; Q59FD3; Q5FWE8; Q86SF8; Q86U45; Q96HK7; Q96HM4; Q96IY5; Q9BTS3"	"mRNA processing"	"Processing of Capped Intron-Containing Pre-mRNA; SUMOylation of RNA binding proteins; mRNA Splicing - Major Pathway; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle"	"6"	"0"	"6806.4"	"4269.8"	"5549.6"	"4708.6"	"5662.0"	"5818.9"	"10996.1"	"9528.9"	"7027.5"	"11363.4"	"14987.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95782"	"AP-2 complex subunit alpha-1 OS=Homo sapiens OX=9606 GN=AP2A1 PE=1 SV=3"	"32"	"26"	"64"	"19"	"977"	"107.5"	"7.03"	"10144.23"	"120.25"	"20"	"25"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01602, Pf02296, Pf02883"	"160"	"ENSG00000196961"	"AP2A1"	"hsa:160; O95782; Q96CI7; Q96PP6; Q96PP7; Q9H070"	"Synaptic vesicle pathway; VEGFA-VEGFR2 signaling; GABA receptor signaling; EGF/EGFR signaling pathway; Fragile X syndrome; mBDNF and proBDNF regulation of GABA neurotransmission"	"MHC class II antigen presentation; Potential therapeutics for SARS; Recycling pathway of L1; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; LDL clearance; Trafficking of GluR2-containing AMPA receptors; Nef Mediated CD4 Down-regulation; Retrograde neurotrophin signalling; Nef Mediated CD8 Down-regulation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation"	"20"	"0"	"358.5"	"235.6"	"385.4"	"394.8"	"436.1"	"425.1"	"1237.2"	"2240.6"	"3921.8"	"7150.0"	"10339.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TAF3"	"WD repeat-containing protein 48 OS=Homo sapiens OX=9606 GN=WDR48 PE=1 SV=1"	"51"	"24"	"49"	"24"	"677"	"76.2"	"7.03"	"6839.00"	"118.60"	"16"	"24"	"DNA metabolism;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00400, Pf11816"	"57599"	"ENSG00000114742"	"WDR48"	"B4DM86; B4DQI2; B4DY84; hsa:57599; Q63HJ2; Q658Y1; Q8N3Z1; Q8TAF3; Q9NSK8; Q9P279"	"DNA repair pathways, full network"	"Ub-specific processing proteases; Recognition of DNA damage by PCNA-containing replication complex; Fanconi Anemia Pathway; Signaling by cytosolic PDGFRA and PDGFRB fusion proteins"	"5"	"0"	"663.7"	"391.8"	"706.9"	"611.1"	"792.6"	"779.2"	"1872.2"	"2103.0"	"2979.6"	"7147.3"	"11640.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19338"	"Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3"	"37"	"34"	"76"	"34"	"710"	"76.6"	"4.70"	"11633.31"	"117.90"	"29"	"29"	"developmental processes;other biological processes"	"plasma membrane;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"4691"	"ENSG00000115053"	"NCL"	"hsa:4691; P19338; Q53SK1; Q8NB06; Q9UCF0; Q9UDG1"	"Pathogenic Escherichia coli infection; VEGFA-VEGFR2 signaling"	"Major pathway of rRNA processing in the nucleolus and cytosol"	"3"	"0"	"6888.1"	"4199.9"	"6153.3"	"5614.0"	"5862.8"	"6091.4"	"19072.9"	"15322.2"	"9792.8"	"13015.5"	"17851.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14866"	"Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2"	"42"	"16"	"47"	"15"	"589"	"64.1"	"8.22"	"8830.78"	"116.19"	"10"	"16"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf11835, Pf13893"	"3191"	"ENSG00000104824; ENSG00000282947"	"HNRNPL"	"A6ND69; A6NIT8; hsa:3191; P14866; Q9H3P3"	"mRNA processing; Hippocampal synaptogenesis and neurogenesis"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"4"	"1"	"2719.4"	"2110.6"	"2481.2"	"2147.5"	"2444.8"	"2561.4"	"5237.2"	"4523.7"	"3244.1"	"5197.1"	"5560.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12270"	"Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3"	"16"	"38"	"75"	"37"	"2363"	"267.1"	"5.02"	"15067.15"	"114.25"	"36"	"31"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"other membranes;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf07926"	"7175"	"ENSG00000047410"	"TPR"	"hsa:7175; P12270; Q15624; Q15655; Q5SWY0; Q99968"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Signaling by ALK fusions and activated point mutants"	"29"	"1"	"2946.1"	"1561.6"	"2346.9"	"2712.0"	"2746.5"	"3263.3"	"6643.3"	"6118.8"	"4457.3"	"7306.2"	"11045.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00571"	"ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3"	"49"	"31"	"67"	"30"	"662"	"73.2"	"7.18"	"11745.41"	"113.95"	"26"	"28"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;translation activity;nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"1654"	"ENSG00000215301"	"DDX3X"	"A8K538; B4E3E8; hsa:1654; O00571; O15536"	"Novel intracellular components of RIG-I-like receptor pathway; Hepatitis B infection"	"Neutrophil degranulation"	"3"	"1"	"2544.0"	"1464.7"	"2054.0"	"1992.5"	"2167.0"	"2266.5"	"7974.3"	"7542.5"	"5141.8"	"6811.8"	"7137.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31943"	"Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4"	"42"	"15"	"55"	"6"	"449"	"49.2"	"6.30"	"9764.79"	"113.81"	"12"	"14"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08080"	"3187"	"ENSG00000169045; ENSG00000284254"	"HNRNPH1"	"B3KW86; D3DWQ2; hsa:3187; P31943; Q6IBM4"	"MECP2 and associated Rett syndrome; mRNA processing; Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells"	"mRNA Splicing - Major Pathway; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA"	"6"	"8"	"2299.8"	"1593.1"	"2179.8"	"2475.7"	"2297.0"	"2860.5"	"4114.9"	"4308.2"	"3284.6"	"4455.8"	"5246.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08133"	"Annexin A6 OS=Homo sapiens OX=9606 GN=ANXA6 PE=1 SV=3"	"42"	"27"	"60"	"27"	"673"	"75.8"	"5.60"	"10222.57"	"112.31"	"19"	"24"	"cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;mitochondrion;other cytoplasmic organelle;other cell component"	"transporter activity;cytoskeletal activity;other molecular function"	"Pf00191"	"309"	"ENSG00000197043"	"ANXA6"	"B7Z8A7; D3DQH4; E9PGK1; hsa:309; P08133; Q6ZT79"	"Calcium regulation in cardiac cells; Prostaglandin synthesis and regulation"	"Smooth Muscle Contraction"	"3"	"0"	"1978.9"	"1224.2"	"2032.4"	"1277.4"	"2076.6"	"1779.8"	"3795.4"	"3230.7"	"2719.3"	"6307.6"	"17733.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q03252"	"Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4"	"41"	"30"	"69"	"25"	"620"	"69.9"	"5.59"	"12247.38"	"110.11"	"29"	"30"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytoskeleton;nucleus"	"cytoskeletal activity;other molecular function"	"Pf00038, Pf00932"	"84823"	"ENSG00000176619"	"LMNB2"	"hsa:84823; O75292; Q03252; Q14734; Q96DF6"	"Gastric cancer network 2; Fas ligand pathway and stress induction of heat shock proteins; IL-18 signaling pathway; Familial partial lipodystrophy; Progeria-associated lipodystrophy; Acquired partial lipodystrophy / Barraquer-Simons syndrome"	""	"6"	"0"	"3795.3"	"2365.8"	"2916.7"	"2808.1"	"3170.4"	"3539.2"	"6203.7"	"5769.3"	"4393.0"	"7286.8"	"9629.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14152"	"Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1"	"24"	"36"	"75"	"36"	"1382"	"166.5"	"6.79"	"13219.10"	"109.30"	"33"	"32"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;translational apparatus;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf01399"	"8661"	"ENSG00000107581"	"EIF3A"	"B1AMV5; B4DYS1; F5H335; hsa:8661; O00653; Q14152; Q15778"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"8"	"0"	"4450.4"	"2858.9"	"3785.6"	"3308.9"	"3843.2"	"3607.5"	"7821.9"	"7138.8"	"5031.8"	"7734.4"	"9996.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62258"	"14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1"	"69"	"19"	"73"	"17"	"255"	"29.2"	"4.74"	"15144.52"	"109.22"	"18"	"16"	"stress response;transport;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00244"	"7531"	"ENSG00000108953; ENSG00000274474"	"YWHAE"	"B3KY71; D3DTH5; hsa:7531; P29360; P42655; P62258; Q4VJB6; Q53XZ5; Q63631; Q7M4R4"	"Cell cycle; Myometrial relaxation and contraction pathways; VEGFA-VEGFR2 signaling; Calcium regulation in cardiac cells; 17p13.3 (YWHAE) copy number variation; Sudden infant death syndrome (SIDS) susceptibility pathways"	"RAB GEFs exchange GTP for GDP on RABs; Translocation of SLC2A4 (GLUT4) to the plasma membrane; TP53 Regulates Metabolic Genes; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Activation of BAD and translocation to mitochondria ; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models; Regulation of HSF1-mediated heat shock response; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Signaling by Hippo; HSF1 activation; NADE modulates death signalling"	"26"	"4"	"3901.3"	"2475.8"	"3328.2"	"3368.3"	"3201.7"	"3630.4"	"5932.7"	"5848.6"	"4704.4"	"6758.6"	"9125.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q10567"	"AP-1 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP1B1 PE=1 SV=2"	"25"	"26"	"57"	"9"	"949"	"104.6"	"5.06"	"9937.10"	"108.69"	"21"	"23"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"226.8"	"148.9"	"197.3"	"187.3"	"227.6"	"232.3"	"451.6"	"639.7"	"897.1"	"1726.1"	"2715.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04075"	"Fructose-bisphosphate aldolase A OS=Homo sapiens OX=9606 GN=ALDOA PE=1 SV=2"	"51"	"25"	"66"	"19"	"364"	"39.4"	"8.09"	"14126.47"	"108.11"	"25"	"20"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00274"	"226"	"ENSG00000149925"	"ALDOA"	"B4DXI7; hsa:226; P04075; Q6FH76; Q6FI10; Q96B15; Q9BWD9; Q9UCN2"	"VEGFA-VEGFR2 signaling; Clear cell renal cell carcinoma pathways; Aerobic glycolysis; 16p11.2 proximal deletion syndrome; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Glycolysis; Gluconeogenesis; Neutrophil degranulation; Platelet degranulation"	"11"	"6"	"5603.7"	"3449.0"	"5448.7"	"4938.2"	"5358.2"	"4984.2"	"8693.2"	"7856.1"	"5941.8"	"8855.3"	"13592.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35527"	"Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3"	"46"	"27"	"64"	"26"	"623"	"62.0"	"5.24"	"11312.87"	"108.04"	"22"	"26"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	"cytoskeletal activity"	"Pf00038"	"3857"	"ENSG00000171403"	"KRT9"	"hsa:3857; O00109; P35527; Q0IJ47; Q14665"	""	"Formation of the cornified envelope"	"2"	"2"	"1115.8"	"361.8"	"26877.7"	"1057.4"	"775.1"	"2948.5"	"5605.1"	"5975.9"	"3168.2"	"8276.0"	"4199.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13639"	"Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4"	"35"	"29"	"65"	"28"	"858"	"95.3"	"6.83"	"12693.94"	"106.21"	"26"	"25"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00009, Pf00679, Pf03144, Pf03764, Pf14492"	"1938"	"ENSG00000167658"	"EEF2"	"A0A384N6H1; B2RMP5; D6W618; hsa:1938; P13639; Q58J86"	"Translation factors; AMP-activated protein kinase signaling; Brain-derived neurotrophic factor (BDNF) signaling pathway; IL-18 signaling pathway"	"Neutrophil degranulation; Protein methylation; Uptake and function of diphtheria toxin; Peptide chain elongation; Synthesis of diphthamide-EEF2"	"9"	"1"	"2872.2"	"1703.8"	"2476.6"	"2392.9"	"2454.5"	"2856.2"	"4657.3"	"4596.1"	"3594.0"	"5600.0"	"9299.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96CW1"	"AP-2 complex subunit mu OS=Homo sapiens OX=9606 GN=AP2M1 PE=1 SV=2"	"45"	"21"	"55"	"21"	"435"	"49.6"	"9.54"	"10244.73"	"105.93"	"14"	"17"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00928, Pf01217"	"1173"	"ENSG00000161203"	"AP2M1"	"A6NE12; D3DNT1; hsa:1173; P20172; P53679; Q96CW1"	"Synaptic vesicle pathway; GABA receptor signaling; EGF/EGFR signaling pathway; Fragile X syndrome; GDNF signaling"	"Potential therapeutics for SARS; EPH-ephrin mediated repulsion of cells; Cargo recognition for clathrin-mediated endocytosis; VLDLR internalisation and degradation; Recycling pathway of L1; MHC class II antigen presentation; WNT5A-dependent internalization of FZD4; LDL clearance; Nef Mediated CD4 Down-regulation; Retrograde neurotrophin signalling; Nef Mediated CD8 Down-regulation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; Nef mediated downregulation of CD28 cell surface expression; Formation of annular gap junctions"	"21"	"0"	"490.5"	"333.6"	"533.3"	"511.5"	"573.2"	"622.4"	"1836.1"	"3567.2"	"6344.2"	"11696.4"	"16925.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60709"	"Actin, cytoplasmic 1 OS=Homo sapiens OX=9606 GN=ACTB PE=1 SV=1"	"35"	"16"	"55"	"3"	"375"	"41.7"	"5.48"	"11086.51"	"105.77"	"13"	"14"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00022"	"60"	"ENSG00000075624"	"ACTB"	"hsa:60; P02570; P60709; P70514; P99021; Q11211; Q64316; Q75MN2; Q96B34; Q96HG5"	"Arrhythmogenic right ventricular cardiomyopathy; Pathogenic Escherichia coli infection; Common pathways underlying drug addiction; Myometrial relaxation and contraction pathways; Focal adhesion; Fas ligand pathway and stress induction of heat shock proteins; Ebola virus infection in host; Acute viral myocarditis; Thermogenesis; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Overlap between signal transduction pathways contributing to LMNA laminopathies; Pleural mesothelioma; Regulation of actin cytoskeleton; Network map of SARS-CoV-2 signaling pathway"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; UCH proteinases; Clathrin-mediated endocytosis; DNA Damage Recognition in GG-NER; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; Recycling pathway of L1; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; RHO GTPases Activate WASPs and WAVEs; RHO GTPases activate IQGAPs; RHO GTPases Activate Formins; RHOF GTPase cycle; B-WICH complex positively regulates rRNA expression; Signaling by BRAF and RAF1 fusions; EPHB-mediated forward signaling; VEGFA-VEGFR2 Pathway; Factors involved in megakaryocyte development and platelet production; EPH-ephrin mediated repulsion of cells; HATs acetylate histones; Interaction between L1 and Ankyrins; Prefoldin mediated transfer of substrate  to CCT/TriC; Signaling by RAF1 mutants; Adherens junctions interactions; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; Formation of annular gap junctions; Folding of actin by CCT/TriC; Cell-extracellular matrix interactions"	"47"	"19"	"5398.5"	"3476.5"	"3906.6"	"2730.4"	"3761.1"	"4647.4"	"5623.5"	"4257.1"	"3636.7"	"6171.9"	"7046.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06748"	"Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2"	"39"	"16"	"64"	"16"	"294"	"32.6"	"4.78"	"12088.88"	"105.51"	"15"	"16"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;translation activity;nucleic acid binding activity;other molecular function"	"Pf03066, Pf16276"	"4869"	"ENSG00000181163"	"NPM1"	"A8K3N7; B5BU00; D3DQL6; hsa:4869; P06748; P08693; Q12826; Q13440; Q13441; Q14115; Q5EU94; Q5EU95; Q5EU96; Q5EU97; Q5EU98; Q5EU99; Q6V962; Q8WTW5; Q96AT6; Q96DC4; Q96EA5; Q9BYG9; Q9UDJ7"	""	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain; Nuclear import of Rev protein; Deposition of new CENPA-containing nucleosomes at the centromere; SUMOylation of transcription cofactors; ALK mutants bind TKIs; Nuclear events stimulated by ALK signaling in cancer; TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation; SARS-CoV-1-host interactions"	"9"	"0"	"4766.2"	"2710.0"	"4241.0"	"4619.6"	"4428.8"	"4997.2"	"15423.8"	"13995.8"	"10600.2"	"14057.2"	"20865.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15149"	"Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3"	"10"	"35"	"60"	"34"	"4684"	"531.5"	"5.96"	"10074.84"	"104.61"	"27"	"31"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00681, Pf03501, Pf17902, Pf18373"	"5339"	"ENSG00000178209"	"PLEC"	"hsa:5339; Q15148; Q15149; Q16640; Q6S376; Q6S377; Q6S378; Q6S379; Q6S380; Q6S381; Q6S382; Q6S383"	"Envelope proteins and their potential roles in EDMD physiopathology"	"Assembly of collagen fibrils and other multimeric structures; Caspase-mediated cleavage of cytoskeletal proteins; Type I hemidesmosome assembly"	"4"	"2"	"2243.4"	"1487.1"	"2005.0"	"1856.5"	"2026.4"	"2302.7"	"4028.0"	"3795.0"	"2874.0"	"4184.7"	"5343.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52597"	"Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3"	"53"	"17"	"51"	"14"	"415"	"45.6"	"5.58"	"6167.61"	"102.23"	"11"	"17"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf08080"	"3185"	"ENSG00000169813"	"HNRNPF"	"B3KM84; hsa:3185; P52597; Q5T0N2; Q96AU2"	"MECP2 and associated Rett syndrome"	"mRNA Splicing - Major Pathway; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"5"	"2"	"3396.5"	"2169.4"	"2892.7"	"3748.8"	"3234.0"	"4252.1"	"4930.2"	"5095.1"	"3808.4"	"4841.9"	"5901.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P17844"	"Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1"	"36"	"28"	"67"	"21"	"614"	"69.1"	"8.92"	"12645.42"	"101.18"	"27"	"24"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf08061"	"1655"	"ENSG00000108654"	"DDX5"	"B4DLW8; B5BU21; D3DU32; E7ETL9; hsa:1655; O75681; P17844; Q53Y61"	"Ciliary landscape"	"mRNA Splicing - Major Pathway; SUMOylation of transcription cofactors; Estrogen-dependent gene expression; Replication of the SARS-CoV-1 genome; Replication of the SARS-CoV-2 genome"	"6"	"0"	"3634.9"	"2169.0"	"2859.6"	"2473.5"	"2935.1"	"2953.5"	"6281.8"	"5210.8"	"3614.1"	"6541.7"	"8444.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35908"	"Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2"	"36"	"24"	"63"	"17"	"639"	"65.4"	"8.00"	"11816.71"	"101.02"	"24"	"23"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;cytosol;cytoskeleton;other cell component"	"bone, tooth or skin structural activity;cytoskeletal activity"	"Pf00038, Pf16208"	"3849"	"ENSG00000172867"	"KRT2"	"hsa:3849; P35908; Q4VAQ2"	""	"Formation of the cornified envelope"	"2"	"4"	"2342.5"	"258.4"	"16201.9"	"668.3"	"551.2"	"1265.3"	"2133.1"	"1366.3"	"1752.0"	"2660.5"	"2707.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14683"	"Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2"	"29"	"35"	"63"	"35"	"1233"	"143.1"	"7.64"	"10298.90"	"99.30"	"29"	"32"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463, Pf06470"	"8243"	"ENSG00000072501"	"SMC1A"	"hsa:8243; O14995; Q14683; Q16351; Q2M228"	"miRNA regulation of DNA damage response; Cell cycle; Retinoblastoma gene in cancer; Constitutive androstane receptor pathway; Nuclear receptors meta-pathway; Pathways affected in adenoid cystic carcinoma; ATM signaling in development and disease ; mRNA processing; Regulation of sister chromatid separation at the metaphase-anaphase transition; Rett syndrome causing genes; CAMKK2 pathway; Cohesin complex - Cornelia de Lange syndrome; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; 10q22q23 copy number variation; DNA damage response"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Estrogen-dependent gene expression; SUMOylation of DNA damage response and repair proteins; Meiotic synapsis; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"22"	"0"	"2187.7"	"1316.0"	"1842.9"	"1710.7"	"2053.9"	"2102.9"	"8456.0"	"7769.2"	"5759.7"	"9299.8"	"13089.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UQE7"	"Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2"	"26"	"30"	"62"	"30"	"1217"	"141.5"	"7.18"	"11140.69"	"97.17"	"28"	"28"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf02463, Pf06470"	"9126"	"ENSG00000108055"	"SMC3"	"A8K156; hsa:9126; O60464; Q5T482; Q9UQE7"	"Cell cycle; Retinoblastoma gene in cancer; MECP2 and associated Rett syndrome; Prion disease pathway; Regulation of sister chromatid separation at the metaphase-anaphase transition; Cohesin complex - Cornelia de Lange syndrome; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; 10q22q23 copy number variation"	"SUMOylation of DNA damage response and repair proteins; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Meiotic synapsis; Estrogen-dependent gene expression; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"15"	"0"	"1423.3"	"948.0"	"1405.4"	"1280.7"	"1550.9"	"1679.2"	"6559.4"	"5979.8"	"4226.4"	"7208.5"	"9597.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14618"	"Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4"	"49"	"19"	"46"	"19"	"531"	"57.9"	"7.84"	"9227.36"	"96.42"	"15"	"16"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00224, Pf02887"	"5315"	"ENSG00000067225"	"PKM"	"A6NFK3; B2R5N8; B3KRY0; B4DFX8; B4DUU6; hsa:5315; P14618; P14786; Q53GK4; Q96E76; Q9BWB5; Q9UCV6; Q9UPF2"	"Photodynamic therapy-induced HIF-1 survival signaling; Amino acid metabolism; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; Glycolysis in senescence; Glucose metabolism in triple-negative breast cancer cells; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"Neutrophil degranulation"	"10"	"0"	"2244.3"	"1152.7"	"1927.9"	"1888.0"	"1765.9"	"2223.6"	"3489.0"	"3466.0"	"2701.9"	"3733.3"	"4262.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15393"	"Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4"	"22"	"25"	"61"	"24"	"1217"	"135.5"	"5.26"	"11095.05"	"95.76"	"23"	"22"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03178, Pf10433"	"23450"	"ENSG00000189091"	"SF3B3"	"hsa:23450; Q15393; Q6NTI8; Q96GC0; Q9BPY2; Q9UFX7; Q9UJ29"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"1"	"3044.1"	"2105.4"	"2969.4"	"2330.9"	"2751.8"	"2639.9"	"5234.8"	"4807.5"	"3584.2"	"6069.2"	"8363.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08238"	"Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4"	"36"	"29"	"62"	"15"	"724"	"83.2"	"5.03"	"10414.15"	"95.61"	"26"	"26"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00183, Pf02518"	"3326"	"ENSG00000096384"	"HSP90AB1"	"B2R5P0; hsa:3326; P08238; Q5T9W7; Q9NQW0; Q9NTK6"	"Nuclear receptors meta-pathway; NRF2 pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway"	"Regulation of actin dynamics for phagocytic cup formation; Potential therapeutics for SARS; The role of GTSE1 in G2/M progression after G2 checkpoint; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Aryl hydrocarbon receptor signalling; Neutrophil degranulation; Estrogen-dependent gene expression; Sema3A PAK dependent Axon repulsion; DDX58/IFIH1-mediated induction of interferon-alpha/beta; The NLRP3 inflammasome; Purinergic signaling in leishmaniasis infection; RHOBTB2 GTPase cycle; Chaperone Mediated Autophagy; HSF1 activation; Attenuation phase; Uptake and function of diphtheria toxin"	"23"	"15"	"4787.7"	"2765.2"	"3687.8"	"3806.7"	"3633.2"	"4969.1"	"5616.0"	"4767.6"	"3597.4"	"6076.3"	"8750.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15233"	"Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4"	"41"	"21"	"60"	"20"	"471"	"54.2"	"8.95"	"11024.86"	"95.06"	"17"	"21"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08075"	"4841"	"ENSG00000147140"	"NONO"	"B7Z4C2; D3DVV4; F5GYZ3; hsa:4841; O00201; P30807; Q12786; Q15233; Q9BQC5"	"mRNA processing"	""	"1"	"0"	"2664.3"	"1668.4"	"2216.3"	"1961.3"	"2293.5"	"1990.0"	"6387.6"	"6125.4"	"4465.8"	"6670.1"	"8613.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2J2"	"Band 4.1-like protein 3 OS=Homo sapiens OX=9606 GN=EPB41L3 PE=1 SV=2"	"24"	"24"	"48"	"21"	"1087"	"120.6"	"5.19"	"9272.82"	"94.39"	"20"	"21"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf04382, Pf05902, Pf08736, Pf09379, Pf09380"	"23136"	"ENSG00000082397"	"EPB41L3"	"B7Z4I5; F5GX05; hsa:23136; O95713; Q9BRP5; Q9Y2J2"	"Splicing factor NOVA regulated synaptic proteins"	"Neurexins and neuroligins; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea"	"4"	"1"	"910.1"	"522.7"	"758.7"	"865.9"	"809.3"	"1015.6"	"2718.6"	"2938.2"	"2695.9"	"5974.5"	"9893.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60506"	"Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2"	"44"	"25"	"53"	"17"	"623"	"69.6"	"8.59"	"10027.77"	"93.96"	"21"	"23"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf18360"	"10492"	"ENSG00000135316"	"SYNCRIP"	"E1P501; E1P502; hsa:10492; O60506; Q53H05; Q5TCG2; Q5TCG3; Q8IW78; Q8N599; Q96LC1; Q96LC2; Q9Y583"	""	""	"0"	"0"	"1122.6"	"835.8"	"1215.4"	"1058.0"	"1114.2"	"1218.5"	"2355.8"	"2072.6"	"1573.8"	"2539.0"	"3292.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63104"	"14-3-3 protein zeta/delta OS=Homo sapiens OX=9606 GN=YWHAZ PE=1 SV=1"	"67"	"16"	"53"	"13"	"245"	"27.7"	"4.79"	"9821.64"	"93.47"	"14"	"15"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00244"	"7534"	"ENSG00000164924"	"YWHAZ"	"A8K1N0; B7Z465; hsa:7534; P29213; P29312; P63104; Q32P43; Q5XJ08; Q6GPI2; Q6IN74; Q6NUR9; Q6P3U9; Q86V33"	"Cell cycle; Prolactin signaling pathway; Pathogenic Escherichia coli infection; Myometrial relaxation and contraction pathways; Hepatitis B infection; GDNF signaling; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Negative regulation of NOTCH4 signaling; Regulation of localization of FOXO transcription factors; Deactivation of the beta-catenin transactivating complex; Interleukin-3, Interleukin-5 and GM-CSF signaling; TP53 Regulates Metabolic Genes; NOTCH4 Activation and Transmission of Signal to the Nucleus; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; Rap1 signalling; KSRP (KHSRP) binds and destabilizes mRNA; GP1b-IX-V activation signalling; Activation of BAD and translocation to mitochondria"	"23"	"1"	"3046.4"	"1797.3"	"2818.8"	"2850.8"	"2828.4"	"3004.7"	"4968.3"	"4445.4"	"3289.2"	"5070.0"	"6808.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15029"	"116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1"	"29"	"25"	"50"	"24"	"972"	"109.4"	"5.00"	"9300.81"	"91.33"	"20"	"23"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf00679, Pf03144, Pf03764, Pf14492, Pf16004"	"9343"	"ENSG00000108883"	"EFTUD2"	"B4DK30; B4DMC0; D3DX58; hsa:9343; K7EJ81; Q15029; Q9BUR0"	"mRNA processing; Ciliary landscape"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"4"	"0"	"1848.9"	"1230.6"	"1664.4"	"1385.1"	"1715.4"	"1663.2"	"3744.2"	"3525.2"	"2694.3"	"4669.2"	"5900.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86XP3"	"ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1"	"27"	"21"	"51"	"21"	"938"	"102.9"	"7.02"	"9839.36"	"90.71"	"19"	"18"	"other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"11325"	"ENSG00000198231"	"DDX42"	"A6NML1; A8KA43; hsa:11325; O75619; Q68G51; Q86XP3; Q96BK1; Q96HR7; Q9Y3V8"	""	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"2"	"0"	"1425.9"	"837.3"	"1095.2"	"1256.0"	"1157.8"	"1351.2"	"3345.6"	"3383.5"	"2696.3"	"3601.4"	"4556.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15459"	"Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1"	"36"	"24"	"48"	"24"	"793"	"88.8"	"5.22"	"9239.64"	"90.43"	"19"	"22"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00240, Pf01805, Pf12230"	"10291"	"ENSG00000099995"	"SF3A1"	"E9PAW1; hsa:10291; Q15459"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"2732.0"	"1807.5"	"2138.5"	"2067.6"	"2307.8"	"2211.4"	"4719.1"	"4546.1"	"3512.5"	"4955.7"	"6853.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P32121"	"Beta-arrestin-2 OS=Homo sapiens OX=9606 GN=ARRB2 PE=1 SV=2"	"50"	"17"	"45"	"15"	"409"	"46.1"	"7.69"	"7745.27"	"90.37"	"14"	"17"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00339, Pf02752"	"409"	"ENSG00000141480"	"ARRB2"	"B4DLW0; B5B0C0; B7WPL3; D3DTK2; H0Y688; hsa:409; P32121; Q0Z8D3; Q2PP19; Q6ICT3; Q8N7Y2; Q9UEQ6"	"Corticotropin-releasing hormone signaling pathway; Complement system; Myometrial relaxation and contraction pathways; Wnt signaling pathway; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Hedgehog signaling pathway; Gastrin signaling pathway; Kisspeptin/kisspeptin receptor system in the ovary; GPR143 in melanocytes and retinal pigment epithelium cells; Calcium regulation in cardiac cells"	"Ub-specific processing proteases; Thrombin signalling through proteinase activated receptors (PARs); Activated NOTCH1 Transmits Signal to the Nucleus; Cargo recognition for clathrin-mediated endocytosis; Activation of SMO; G alpha (s) signalling events; Signaling by BRAF and RAF1 fusions; WNT5A-dependent internalization of FZD4; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants"	"27"	"2"	"481.9"	"283.4"	"457.1"	"493.9"	"520.2"	"604.3"	"1764.4"	"3952.6"	"5921.1"	"9001.3"	"9880.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31946"	"14-3-3 protein beta/alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3"	"64"	"15"	"50"	"9"	"246"	"28.1"	"4.83"	"10064.25"	"89.50"	"14"	"13"	"transport;signal transduction;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00244"	"7529"	"ENSG00000166913"	"YWHAB"	"A8K9K2; E1P616; hsa:7529; P31946"	"Cell cycle; IL-3 signaling pathway; Myometrial relaxation and contraction pathways; Hepatitis B infection; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Regulation of localization of FOXO transcription factors; Signaling by BRAF and RAF1 fusions; mTORC1-mediated signalling; TP53 Regulates Metabolic Genes; Signaling by Hippo; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RAF activation; SHOC2 M1731 mutant abolishes MRAS complex function; Gain-of-function MRAS complexes activate RAF signaling; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; Rap1 signalling; MAP2K and MAPK activation; Negative regulation of MAPK pathway; Signaling by high-kinase activity BRAF mutants; Frs2-mediated activation; ARMS-mediated activation; Activation of BAD and translocation to mitochondria ; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"	"33"	"6"	"1836.2"	"1328.2"	"1736.1"	"1983.5"	"1749.5"	"2127.0"	"3682.1"	"3613.8"	"2876.3"	"3889.1"	"5000.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P43243"	"Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2"	"25"	"24"	"56"	"24"	"847"	"94.6"	"6.25"	"10779.06"	"89.42"	"21"	"19"	"stress response;developmental processes;other biological processes"	"other membranes;nucleus"	"nucleic acid binding activity;other molecular function"	""	"9782"	"ENSG00000015479"	"MATR3"	"B7ZAV5; D3DQC3; hsa:9782; P43243; Q9UHW0; Q9UQ27"	""	""	"0"	"0"	"3687.6"	"2495.8"	"2962.1"	"2786.4"	"3256.9"	"3630.8"	"5248.3"	"4220.8"	"3105.7"	"5997.9"	"7745.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14979"	"Heterogeneous nuclear ribonucleoprotein D-like OS=Homo sapiens OX=9606 GN=HNRNPDL PE=1 SV=3"	"30"	"14"	"52"	"12"	"420"	"46.4"	"9.57"	"10190.59"	"89.35"	"14"	"14"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity"	"Pf00076"	"9987"	"ENSG00000152795"	"HNRNPDL"	"hsa:9987; O14979; Q6SPF2; Q7KZ74; Q7KZ75; Q96IM0; Q96S43"	""	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"1"	"0"	"1977.8"	"1093.9"	"1498.9"	"1473.1"	"1588.2"	"1769.1"	"3415.4"	"2907.4"	"2096.3"	"3777.7"	"4986.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51991"	"Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2"	"39"	"14"	"48"	"12"	"378"	"39.6"	"9.01"	"8960.07"	"88.03"	"11"	"13"	"RNA metabolism OR transcription;other metabolic processes;transport"	"nucleus;other cell component"	"transporter activity;nucleic acid binding activity"	"Pf00076"	"220988"	"ENSG00000170144"	"HNRNPA3"	"D3DPF4; hsa:220988; P51991; Q53RW7; Q6URK5"	""	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"2"	"0"	"1775.1"	"1458.5"	"1628.9"	"1715.1"	"1694.9"	"1950.0"	"3533.5"	"3451.8"	"2697.7"	"4165.2"	"4499.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99729"	"Heterogeneous nuclear ribonucleoprotein A/B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2"	"31"	"17"	"56"	"15"	"332"	"36.2"	"8.21"	"10104.99"	"87.03"	"16"	"15"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08143"	"3182"	"ENSG00000197451"	"HNRNPAB"	"B3KNN5; D3DWP7; hsa:3182; Q04150; Q8N7U3; Q99729; Q9BQ99"	"Pre-implantation embryo; mRNA processing"	""	"2"	"0"	"3093.3"	"1817.5"	"2654.5"	"2539.2"	"2681.2"	"2733.3"	"5756.3"	"4778.4"	"3196.8"	"5669.7"	"8218.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92804"	"TATA-binding protein-associated factor 2N OS=Homo sapiens OX=9606 GN=TAF15 PE=1 SV=1"	"23"	"10"	"39"	"6"	"592"	"61.8"	"8.02"	"4911.98"	"85.61"	"6"	"9"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00641"	"8148"	"ENSG00000270647; ENSG00000276833"	"TAF15"	"B2R837; hsa:8148; Q86X94; Q92751; Q92804"	"17q12 copy number variation syndrome"	"Regulation of TP53 Activity through Phosphorylation; RNA Polymerase II Pre-transcription Events; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation"	"10"	"0"	"639.7"	"446.7"	"649.8"	"563.7"	"639.3"	"576.0"	"1399.0"	"1324.2"	"1006.0"	"1420.9"	"1347.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13645"	"Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6"	"32"	"19"	"47"	"16"	"584"	"58.8"	"5.21"	"8899.08"	"84.51"	"18"	"18"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;cytosol;cytoskeleton;other cell component"	"bone, tooth or skin structural activity;other molecular function"	"Pf00038"	"3858"	"ENSG00000186395"	"KRT10"	"hsa:3858; P13645; Q14664; Q8N175"	""	"Formation of the cornified envelope"	"2"	"3"	"1722.1"	"224.9"	"23415.7"	"822.3"	"174.6"	"1484.4"	"2683.2"	"1544.2"	"1665.4"	"2613.5"	"2021.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05455"	"Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2"	"53"	"21"	"53"	"21"	"408"	"46.8"	"7.12"	"10200.02"	"84.30"	"20"	"19"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf05383, Pf08777"	"6741"	"ENSG00000138385"	"SSB"	"hsa:6741; P05455; Q15367; Q53XJ4"	""	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Termination"	"2"	"0"	"2773.4"	"1600.3"	"2438.8"	"2042.1"	"2221.3"	"2292.6"	"5263.7"	"4609.6"	"3140.4"	"5060.1"	"7688.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P68363"	"Tubulin alpha-1B chain OS=Homo sapiens OX=9606 GN=TUBA1B PE=1 SV=1"	"32"	"12"	"45"	"1"	"451"	"50.1"	"5.06"	"7902.21"	"83.78"	"11"	"12"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00091, Pf03953"	"10376"	"ENSG00000123416"	"TUBA1B"	"hsa:10376; P04687; P05209; P68363; Q27I68; Q8WU19"	"Alzheimer's disease and miRNA effects; Pathogenic Escherichia coli infection; Allograft rejection; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"Recycling pathway of L1; COPI-dependent Golgi-to-ER retrograde traffic; MHC class II antigen presentation; Kinesins; HCMV Early Events; RHO GTPases Activate Formins; Intraflagellar transport; Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane; Gap junction assembly; Resolution of Sister Chromatid Cohesion; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recruitment of NuMA to mitotic centrosomes; Formation of tubulin folding intermediates by CCT/TriC; Post-chaperonin tubulin folding pathway; RHO GTPases activate IQGAPs; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Carboxyterminal post-translational modifications of tubulin; Assembly and cell surface presentation of NMDA receptors; Activation of AMPK downstream of NMDARs; Aggrephagy; EML4 and NUDC in mitotic spindle formation; Sealing of the nuclear envelope (NE) by ESCRT-III; Hedgehog 'off' state; RHOH GTPase cycle"	"35"	"11"	"2520.0"	"1596.8"	"2179.7"	"1705.7"	"2056.8"	"2228.8"	"2675.0"	"2415.1"	"1912.5"	"3335.9"	"4370.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62316"	"Small nuclear ribonucleoprotein Sm D2 OS=Homo sapiens OX=9606 GN=SNRPD2 PE=1 SV=1"	"65"	"12"	"52"	"12"	"118"	"13.5"	"9.91"	"10280.62"	"83.29"	"10"	"12"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf01423"	"6633"	"ENSG00000125743"	"SNRPD2"	"A8K797; hsa:6633; J3KPM5; P43330; P62316"	"mRNA processing"	"mRNA Splicing - Major Pathway; SARS-CoV-2 modulates host translation machinery; snRNP Assembly; mRNA Splicing - Minor Pathway"	"5"	"0"	"1912.6"	"1335.4"	"1832.6"	"1558.9"	"1762.9"	"1547.0"	"4395.7"	"3880.8"	"2742.4"	"4278.1"	"6017.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P34897"	"Serine hydroxymethyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=SHMT2 PE=1 SV=3"	"38"	"15"	"43"	"14"	"504"	"56.0"	"8.53"	"7043.70"	"82.38"	"13"	"14"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00464"	"6472"	"ENSG00000182199"	"SHMT2"	"B7Z9F1; E7EQ19; E7EU43; hsa:6472; O00740; P34897; Q8N1A5"	"Glycine metabolism; Vitamin B12 metabolism; Folate metabolism; One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Neuroinflammation and glutamatergic signaling; Metabolic Epileptic Disorders"	"RHOG GTPase cycle; Metabolism of folate and pterines"	"11"	"2"	"1144.2"	"814.6"	"1223.4"	"1105.0"	"1125.9"	"1262.2"	"3716.6"	"3504.2"	"2636.3"	"3722.9"	"4562.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BXP5"	"Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1"	"30"	"25"	"46"	"25"	"876"	"100.6"	"5.96"	"8712.50"	"82.22"	"21"	"23"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04959, Pf12066"	"51593"	"ENSG00000087087"	"SRRT"	"A4D2E5; A4D2E6; A6NK22; B4DJL4; B4DZA6; hsa:51593; O95808; Q32MI4; Q6NT74; Q8TDQ5; Q9BWP6; Q9BXP4; Q9BXP5; Q9Y4S4"	""	"mRNA Splicing - Major Pathway; RNA polymerase II transcribes snRNA genes"	"2"	"0"	"2886.4"	"1563.3"	"2212.3"	"2506.4"	"2395.7"	"2931.9"	"5412.5"	"5045.9"	"3484.0"	"5136.1"	"7287.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y450"	"HBS1-like protein OS=Homo sapiens OX=9606 GN=HBS1L PE=1 SV=1"	"32"	"19"	"42"	"19"	"684"	"75.4"	"6.61"	"8005.70"	"81.36"	"18"	"19"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03143, Pf03144, Pf08938"	"10767"	"ENSG00000112339"	"HBS1L"	"B7Z365; hsa:10767; Q4VX89; Q4VX90; Q5T7G3; Q8NDW9; Q9UPW3; Q9Y450"	""	"mRNA decay by 3' to 5' exoribonuclease"	"1"	"0"	"431.9"	"253.2"	"416.8"	"413.8"	"459.8"	"482.7"	"1573.3"	"2779.0"	"4704.8"	"9063.8"	"10101.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P57772"	"Selenocysteine-specific elongation factor OS=Homo sapiens OX=9606 GN=EEFSEC PE=1 SV=4"	"28"	"19"	"44"	"19"	"596"	"65.3"	"8.35"	"7887.62"	"80.68"	"14"	"18"	"protein metabolism;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009"	"60678"	"ENSG00000132394; ENSG00000284869"	"EEFSEC"	"hsa:60678; P57772; Q96HZ6"	""	"Selenocysteine synthesis"	"1"	"0"	"888.6"	"557.2"	"848.0"	"724.9"	"856.8"	"804.8"	"3594.5"	"6772.3"	"6299.6"	"8942.5"	"10706.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07437"	"Tubulin beta chain OS=Homo sapiens OX=9606 GN=TUBB PE=1 SV=2"	"41"	"12"	"42"	"3"	"444"	"49.6"	"4.89"	"8353.49"	"79.75"	"10"	"11"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;other biological processes"	"non-structural extracellular;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00091, Pf03953"	"203068"	"ENSG00000183311; ENSG00000196230; ENSG00000224156; ENSG00000227739; ENSG00000229684; ENSG00000232421; ENSG00000232575; ENSG00000235067"	"TUBB"	"hsa:203068; P05218; P07437; Q8WUC1; Q9CY33"	"Alzheimer's disease and miRNA effects; Pathogenic Escherichia coli infection; Parkin-ubiquitin proteasomal system pathway; Opioid receptor pathways; Alzheimer's disease"	"Potential therapeutics for SARS; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Neutrophil degranulation"	"14"	"14"	"1343.7"	"894.7"	"1141.1"	"1096.9"	"1182.1"	"1259.3"	"1679.7"	"1562.5"	"1182.0"	"2058.4"	"2646.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00610"	"Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5"	"14"	"19"	"42"	"19"	"1675"	"191.5"	"5.69"	"6924.21"	"79.73"	"15"	"19"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00637, Pf01394, Pf09268, Pf13838"	"1213"	"ENSG00000141367"	"CLTC"	"D3DU00; hsa:1213; Q00610; Q6N0A0; Q86TF2"	"Synaptic vesicle pathway; VEGFA-VEGFR2 signaling; Ebola virus infection in host; Fragile X syndrome; 7q11.23 copy number variation syndrome; Complement and coagulation cascades"	"Recycling pathway of L1; MHC class II antigen presentation; ALK mutants bind TKIs; Nuclear events stimulated by ALK signaling in cancer; RHOV GTPase cycle; Lysosome Vesicle Biogenesis; RHOU GTPase cycle; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; LDL clearance; Retrograde neurotrophin signalling; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation; Entry of Influenza Virion into Host Cell via Endocytosis; Formation of annular gap junctions"	"25"	"0"	"2427.5"	"1603.3"	"2354.2"	"1862.5"	"2201.4"	"2159.0"	"2547.3"	"2364.3"	"1698.7"	"2917.0"	"3929.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55795"	"Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1"	"38"	"13"	"41"	"6"	"449"	"49.2"	"6.30"	"7211.14"	"79.40"	"11"	"12"	"other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00076, Pf08080"	"3188"	"ENSG00000126945"	"HNRNPH2"	"A1L400; hsa:3188; P55795; Q9HHA7"	"mRNA processing"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"3"	"0"	"511.3"	"344.6"	"560.2"	"581.0"	"637.6"	"735.1"	"1003.4"	"922.6"	"626.9"	"1043.4"	"1205.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q07955"	"Serine/arginine-rich splicing factor 1 OS=Homo sapiens OX=9606 GN=SRSF1 PE=1 SV=2"	"44"	"14"	"43"	"14"	"248"	"27.7"	"10.36"	"6752.16"	"79.14"	"11"	"13"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6426"	"ENSG00000136450"	"SRSF1"	"B2R6Z7; D3DTZ3; hsa:6426; Q07955; Q13809"	"mRNA processing"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Minor Pathway"	"7"	"0"	"1864.4"	"1483.8"	"1646.5"	"1544.7"	"1610.4"	"1800.8"	"4522.2"	"4842.9"	"4867.2"	"5640.4"	"5575.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q71U36"	"Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1"	"32"	"12"	"43"	"1"	"451"	"50.1"	"5.06"	"7443.75"	"78.98"	"11"	"12"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00091, Pf03953"	"7846"	"ENSG00000167552"	"TUBA1A"	"A8K0B8; G3V1U9; hsa:7846; P04687; P05209; Q71U36"	"Alzheimer's disease and miRNA effects; Pathogenic Escherichia coli infection; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease; PAFAH1B1 copy number variation"	"COPI-dependent Golgi-to-ER retrograde traffic; Separation of Sister Chromatids; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Kinesins; The role of GTSE1 in G2/M progression after G2 checkpoint; RHO GTPases activate IQGAPs; HCMV Early Events; Recycling pathway of L1; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recruitment of mitotic centrosome proteins and complexes; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Formation of tubulin folding intermediates by CCT/TriC; Prefoldin mediated transfer of substrate  to CCT/TriC; Hedgehog 'off' state; COPI-mediated anterograde transport; Intraflagellar transport; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane; Gap junction assembly; Post-chaperonin tubulin folding pathway; COPI-independent Golgi-to-ER retrograde traffic; Carboxyterminal post-translational modifications of tubulin; Assembly and cell surface presentation of NMDA receptors; Activation of AMPK downstream of NMDARs; Aggrephagy; Sealing of the nuclear envelope (NE) by ESCRT-III"	"41"	"0"	"70.9"	"37.6"	"63.8"	"51.6"	"51.6"	"52.7"	"66.2"	"51.2"	"33.7"	"67.9"	"109.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08865"	"40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4"	"55"	"17"	"35"	"17"	"295"	"32.8"	"4.87"	"5412.27"	"78.45"	"12"	"14"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;translational apparatus;nucleus;other cell component"	"translation activity;other molecular function"	"Pf00318, Pf16122"	"3921"	"ENSG00000168028"	"RPSA"	"hsa:3921; P08865; P11085; P12030; Q16471; Q6IPD1; Q6IPD2; Q6NSD1; Q6NXQ8; Q86VC0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"1041.9"	"697.1"	"819.6"	"743.2"	"879.0"	"873.5"	"2672.7"	"2647.3"	"1854.1"	"2785.1"	"2783.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95602"	"DNA-directed RNA polymerase I subunit RPA1 OS=Homo sapiens OX=9606 GN=POLR1A PE=1 SV=2"	"17"	"22"	"42"	"22"	"1720"	"194.7"	"7.03"	"6641.40"	"77.66"	"18"	"21"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00623, Pf04983, Pf04997, Pf04998, Pf05000"	"25885"	"ENSG00000068654"	"POLR1A"	"B7Z7T0; D6W5M0; hsa:25885; O95602; Q0VG05; Q9UEH0; Q9UFT9"	"Pyrimidine metabolism; Eukaryotic transcription initiation; 2q13 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"8"	"0"	"642.8"	"420.9"	"658.6"	"671.3"	"694.6"	"771.5"	"1493.8"	"3059.4"	"3635.5"	"6668.2"	"8750.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23396"	"40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2"	"67"	"16"	"44"	"16"	"243"	"26.7"	"9.66"	"8159.77"	"76.99"	"14"	"14"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;translational apparatus;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00189, Pf07650"	"6188"	"ENSG00000149273"	"RPS3"	"B2R7N5; hsa:6188; J3KN86; P23396; Q498B5; Q8NI95"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"2646.7"	"1686.4"	"2449.1"	"1725.7"	"2089.0"	"1952.3"	"4774.8"	"4215.2"	"3036.2"	"4731.2"	"6939.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13010"	"X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3"	"30"	"20"	"42"	"20"	"732"	"82.7"	"5.81"	"7091.25"	"76.34"	"16"	"18"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf02735, Pf03730, Pf03731, Pf08785"	"7520"	"ENSG00000079246"	"XRCC5"	"A8K3X5; hsa:7520; P13010; Q0Z7V0; Q4VBQ5; Q53HH7; Q7M4N0; Q9UCQ0; Q9UCQ1"	"Non-homologous end joining; Male infertility; DNA repair pathways, full network; p53 transcriptional gene network"	"Neutrophil degranulation; Cytosolic sensors of pathogen-associated DNA ; Nonhomologous End-Joining (NHEJ); 2-LTR circle formation; IRF3-mediated induction of type I IFN"	"9"	"0"	"1885.9"	"1130.5"	"1666.1"	"1279.9"	"1559.5"	"1515.5"	"3654.0"	"3410.8"	"2329.0"	"3724.1"	"5119.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P40926"	"Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3"	"46"	"13"	"43"	"13"	"338"	"35.5"	"8.68"	"7180.68"	"76.23"	"12"	"13"	"other metabolic processes"	"other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf00056, Pf02866"	"4191"	"ENSG00000146701"	"MDH2"	"A8K414; B2RE78; B4DE44; E9PDB2; hsa:4191; O43682; P40926"	"Amino acid metabolism; Metabolic reprogramming in colon cancer; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders; TCA cycle (aka Krebs or citric acid cycle)"	"Gluconeogenesis; Citric acid cycle (TCA cycle)"	"8"	"0"	"2383.5"	"1373.2"	"2164.1"	"2173.1"	"2151.8"	"2353.4"	"3794.4"	"3615.8"	"2915.5"	"4297.6"	"6847.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52272"	"Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3"	"35"	"24"	"51"	"24"	"730"	"77.5"	"8.70"	"8142.70"	"75.96"	"21"	"22"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf11532"	"4670"	"ENSG00000099783"	"HNRNPM"	"hsa:4670; P52272; Q15584; Q8WZ44; Q96H56; Q9BWL9; Q9Y492"	"mRNA processing"	"mRNA Splicing - Major Pathway; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA"	"4"	"0"	"3247.0"	"2115.9"	"2600.6"	"2241.9"	"2845.1"	"2967.9"	"4809.9"	"4222.2"	"3216.8"	"5735.3"	"7375.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P68371"	"Tubulin beta-4B chain OS=Homo sapiens OX=9606 GN=TUBB4B PE=1 SV=1"	"37"	"11"	"39"	"2"	"445"	"49.8"	"4.89"	"7171.07"	"75.26"	"9"	"11"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response"	"non-structural extracellular;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00091, Pf03953"	"10383"	"ENSG00000188229"	"TUBB4B"	"A2BFA2; hsa:10383; P05217; P68371"	"Alzheimer's disease and miRNA effects; Pathogenic Escherichia coli infection; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"MHC class II antigen presentation; COPI-mediated anterograde transport; HCMV Early Events; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Neutrophil degranulation; Formation of tubulin folding intermediates by CCT/TriC; Prefoldin mediated transfer of substrate  to CCT/TriC; COPI-dependent Golgi-to-ER retrograde traffic; Recycling pathway of L1; Translocation of SLC2A4 (GLUT4) to the plasma membrane; RHO GTPases activate IQGAPs; Intraflagellar transport; The role of GTSE1 in G2/M progression after G2 checkpoint; Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane; Gap junction assembly; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Post-chaperonin tubulin folding pathway; COPI-independent Golgi-to-ER retrograde traffic; Carboxyterminal post-translational modifications of tubulin; Assembly and cell surface presentation of NMDA receptors; Activation of AMPK downstream of NMDARs; Aggrephagy; Sealing of the nuclear envelope (NE) by ESCRT-III; Kinesins; Hedgehog 'off' state"	"41"	"0"	"83.2"	"58.4"	"72.5"	"73.4"	"70.5"	"95.3"	"115.2"	"107.5"	"90.7"	"153.5"	"162.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62736"	"Actin, aortic smooth muscle OS=Homo sapiens OX=9606 GN=ACTA2 PE=1 SV=1"	"25"	"14"	"48"	"1"	"377"	"42.0"	"5.39"	"9563.37"	"74.88"	"12"	"12"	"developmental processes;other biological processes"	"extracellular matrix;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00022"	"59"	"ENSG00000107796"	"ACTA2"	"B2R8A4; hsa:59; P03996; P04108; P62736; Q6FI19"	"Myometrial relaxation and contraction pathways; Striated muscle contraction pathway; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; 22q11.2 copy number variation syndrome; IL-18 signaling pathway; Regucalcin in proximal tubule epithelial kidney cells; Angiotensin II receptor type 1 pathway; Pleural mesothelioma; CCL18 signaling pathway; Urotensin-II-mediated signaling pathway; Markers of kidney cell lineage; Comprehensive IL-17A signaling; IL-26 signaling pathways; A network map of Macrophage-stimulating protein (MSP) signaling"	"Smooth Muscle Contraction; NOTCH4 Intracellular Domain Regulates Transcription"	"16"	"0"	"176.8"	"138.8"	"148.0"	"119.8"	"170.3"	"146.9"	"256.9"	"211.4"	"155.2"	"318.3"	"361.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07900"	"Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5"	"31"	"23"	"50"	"9"	"732"	"84.6"	"5.02"	"8217.08"	"74.62"	"21"	"21"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"non-structural extracellular;extracellular matrix;plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00183, Pf02518"	"3320"	"ENSG00000080824"	"HSP90AA1"	"A8K500; B3KPJ9; hsa:3320; P07900; Q2PP14; Q5CAQ6; Q5CAQ7; Q9BVQ5"	"Nucleotide-binding oligomerization domain (NOD) pathway; TNF-alpha signaling pathway; Corticotropin-releasing hormone signaling pathway; Aryl hydrocarbon receptor pathway; Ebstein-Barr virus LMP1 signaling; Aryl hydrocarbon receptor pathway; Constitutive androstane receptor pathway; Pregnane X receptor pathway; Glucocorticoid receptor pathway; Nuclear receptors meta-pathway; NRF2 pathway; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Th17 cell differentiation pathway"	"Neutrophil degranulation; Estrogen-dependent gene expression; Regulation of actin dynamics for phagocytic cup formation; Potential therapeutics for SARS; The role of GTSE1 in G2/M progression after G2 checkpoint; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recruitment of NuMA to mitotic centrosomes; Aggrephagy; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Extra-nuclear estrogen signaling; vRNP Assembly; Regulation of necroptotic cell death; Interleukin-4 and Interleukin-13 signaling; Downregulation of ERBB2 signaling; Signaling by ERBB2 KD Mutants; Signaling by ERBB2 TMD/JMD mutants; Sema3A PAK dependent Axon repulsion; DDX58/IFIH1-mediated induction of interferon-alpha/beta; PIWI-interacting RNA (piRNA) biogenesis; VEGFR2 mediated vascular permeability; RHOBTB2 GTPase cycle; Chaperone Mediated Autophagy; HSF1 activation; Attenuation phase; eNOS activation; Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; Constitutive Signaling by EGFRvIII; Signaling by ERBB2 ECD mutants; Uptake and function of diphtheria toxin; Constitutive Signaling by Overexpressed ERBB2; Scavenging by Class F Receptors; Drug-mediated inhibition of ERBB2 signaling; Resistance of ERBB2 KD mutants to trastuzumab; Resistance of ERBB2 KD mutants to sapitinib; Resistance of ERBB2 KD mutants to tesevatinib; Resistance of ERBB2 KD mutants to neratinib; Resistance of ERBB2 KD mutants to osimertinib; Resistance of ERBB2 KD mutants to afatinib; Resistance of ERBB2 KD mutants to AEE788; Resistance of ERBB2 KD mutants to lapatinib; Drug resistance in ERBB2 TMD/JMD mutants"	"67"	"0"	"1046.1"	"675.5"	"860.8"	"661.3"	"788.8"	"999.4"	"1133.4"	"903.2"	"621.4"	"1296.9"	"2027.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26368"	"Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4"	"34"	"13"	"38"	"13"	"475"	"53.5"	"9.09"	"6005.59"	"73.22"	"9"	"11"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"11338"	"ENSG00000063244"	"U2AF2"	"hsa:11338; P26368; Q96HC5"	"mRNA processing; Warburg effect modulated by deubiquitinating enzymes and their substrates"	"mRNA Splicing - Major Pathway; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"6"	"0"	"1896.9"	"1197.5"	"1860.2"	"1409.7"	"1704.6"	"1813.6"	"5530.3"	"4683.3"	"2668.1"	"4094.4"	"5774.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09874"	"Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4"	"23"	"21"	"45"	"21"	"1014"	"113.0"	"8.88"	"9122.10"	"73.00"	"19"	"18"	"cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00533, Pf00644, Pf00645, Pf02877, Pf05406, Pf08063"	"142"	"ENSG00000143799"	"PARP1"	"B1ANJ4; hsa:142; P09874; Q8IUZ9"	"Corticotropin-releasing hormone signaling pathway; Nanoparticle triggered regulated necrosis; Fas ligand pathway and stress induction of heat shock proteins; NAD metabolism, sirtuins and aging; NAD+ metabolism; NAD+ biosynthetic pathways; Breast cancer pathway; Acute viral myocarditis; Joubert syndrome; Male infertility; Base excision repair; IL-18 signaling pathway; DNA repair pathways, full network; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Progeria-associated lipodystrophy; Primary ovarian insufficiency; A network map of Macrophage-stimulating protein (MSP) signaling"	"SUMOylation of DNA damage response and repair proteins; Downregulation of SMAD2/3:SMAD4 transcriptional activity; HDR through MMEJ (alt-NHEJ); Formation of Incision Complex in GG-NER; DNA Damage Recognition in GG-NER; vRNA Synthesis; POLB-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER"	"25"	"0"	"498.8"	"335.3"	"559.7"	"482.0"	"513.6"	"554.2"	"3442.2"	"3367.5"	"2931.6"	"7168.0"	"13696.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08621"	"U1 small nuclear ribonucleoprotein 70 kDa OS=Homo sapiens OX=9606 GN=SNRNP70 PE=1 SV=2"	"46"	"17"	"38"	"17"	"437"	"51.5"	"9.94"	"6109.59"	"72.23"	"11"	"17"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf12220"	"6625"	"ENSG00000104852"	"SNRNP70"	"B3KUA3; hsa:6625; P08621; P78493; P78494; Q15364; Q15686; Q15687; Q15689; Q99377; Q9UE45; Q9UE46; Q9UE47; Q9UE48; Q9UFQ6"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"1881.1"	"1174.9"	"1643.0"	"1365.7"	"1763.8"	"1480.6"	"4042.8"	"3865.0"	"2676.7"	"4382.9"	"6259.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61247"	"40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2"	"61"	"19"	"50"	"19"	"264"	"29.9"	"9.73"	"8529.92"	"71.85"	"18"	"17"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01015"	"6189"	"ENSG00000145425"	"RPS3A"	"B2R4D4; D3DP05; hsa:6189; P33443; P49241; P61247"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Peptide chain elongation; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"3054.6"	"2064.9"	"2707.3"	"2337.2"	"2490.8"	"2640.8"	"8309.1"	"7526.0"	"5133.9"	"7534.5"	"9590.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13838"	"Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1"	"33"	"15"	"51"	"7"	"428"	"49.0"	"5.67"	"10772.49"	"71.66"	"15"	"13"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"7919"	"ENSG00000198563; ENSG00000215425; ENSG00000225073; ENSG00000225859; ENSG00000229496; ENSG00000230624; ENSG00000235439"	"DDX39B"	"B0S8C0; hsa:7919; O43496; Q0EFA1; Q13838; Q2L6F9; Q53GL9; Q5RJ64; Q5RJ66; Q5ST94; Q5STB4; Q5STB5; Q5STB7; Q5STB8; Q5STU4; Q5STU5; Q5STU6; Q5STU8; Q71V76"	""	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; RHOBTB2 GTPase cycle; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"5"	"9"	"1521.5"	"945.8"	"1453.7"	"1417.1"	"1476.5"	"1727.4"	"2436.7"	"2204.2"	"1753.4"	"2710.7"	"3410.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13797"	"Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3 PE=1 SV=4"	"34"	"21"	"38"	"21"	"630"	"70.8"	"5.60"	"6862.84"	"71.42"	"17"	"21"	"cell organization and biogenesis;developmental processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf13499"	"5358"	"ENSG00000102024"	"PLS3"	"A8K579; B1AQ09; B4DGB4; B7Z6M1; hsa:5358; P13797; Q86YI6"	""	""	"0"	"0"	"1826.9"	"1352.4"	"1677.1"	"1672.5"	"1684.5"	"1886.7"	"2519.5"	"2142.5"	"1587.9"	"2693.2"	"4261.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P68104"	"Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1"	"38"	"16"	"42"	"9"	"462"	"50.1"	"9.01"	"6509.62"	"70.37"	"12"	"14"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;translational apparatus;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03143, Pf03144"	"1915"	"ENSG00000156508"	"EEF1A1"	"hsa:1915; P04719; P04720; P68104; Q6IQ15"	"Translation factors; Fragile X syndrome; 2q37 copy number variation syndrome"	"Neutrophil degranulation; Chaperone Mediated Autophagy; Protein methylation; Peptide chain elongation; HSF1 activation; SARS-CoV-1 modulates host translation machinery"	"10"	"8"	"3437.3"	"1811.5"	"2669.0"	"2497.4"	"2455.7"	"3006.1"	"7918.5"	"7726.8"	"6304.7"	"9035.5"	"12545.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99459"	"Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2"	"28"	"19"	"37"	"19"	"802"	"92.2"	"8.18"	"6957.44"	"69.57"	"18"	"17"	"cell cycle OR cell proliferation;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf11831, Pf13921"	"988"	"ENSG00000096401"	"CDC5L"	"hsa:988; Q76N46; Q99459; Q99974"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"1371.1"	"913.6"	"1266.1"	"1246.6"	"1318.7"	"1483.4"	"3653.2"	"3761.2"	"2473.3"	"4423.4"	"6808.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75533"	"Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3"	"19"	"21"	"42"	"21"	"1304"	"145.7"	"7.09"	"7298.38"	"69.47"	"18"	"18"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf08920"	"23451"	"ENSG00000115524"	"SF3B1"	"E9PCH3; hsa:23451; O75533"	"mRNA processing; 10q11.21q11.23 copy number variation syndrome"	"mRNA Splicing - Major Pathway; B-WICH complex positively regulates rRNA expression; mRNA Splicing - Minor Pathway"	"5"	"0"	"2109.5"	"1287.2"	"1854.9"	"1546.4"	"1865.2"	"1745.6"	"3840.9"	"3404.5"	"2415.8"	"4111.6"	"5804.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P24534"	"Elongation factor 1-beta OS=Homo sapiens OX=9606 GN=EEF1B2 PE=1 SV=3"	"68"	"14"	"37"	"11"	"225"	"24.7"	"4.67"	"7249.11"	"68.94"	"10"	"12"	"protein metabolism;other metabolic processes"	"cytosol;other cell component"	"enzyme regulator activity;nucleic acid binding activity"	"Pf00736, Pf10587"	"1933"	"ENSG00000114942; ENSG00000283391"	"EEF1B2"	"A8K795; hsa:1933; P24534; Q6IBH9"	"Translation factors"	"Eukaryotic Translation Elongation"	"2"	"4"	"2997.6"	"1468.1"	"2224.0"	"2538.4"	"2248.8"	"2674.4"	"5387.0"	"5348.8"	"3980.6"	"5709.1"	"7985.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P10809"	"60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2"	"33"	"20"	"47"	"20"	"573"	"61.0"	"5.87"	"8269.30"	"68.92"	"20"	"19"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00118"	"3329"	"ENSG00000144381"	"HSPD1"	"B2R5M6; B7Z712; hsa:3329; P10809; Q38L19; Q9UCR6"	"Apoptosis-related network due to altered Notch3 in ovarian cancer; 8p23.1 copy number variation syndrome; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Mitochondrial protein import; TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"	"5"	"0"	"4242.6"	"2196.2"	"2898.2"	"2360.8"	"2816.1"	"3414.6"	"4272.2"	"3370.5"	"2403.2"	"4517.7"	"6003.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UQ35"	"Serine/arginine repetitive matrix protein 2 OS=Homo sapiens OX=9606 GN=SRRM2 PE=1 SV=2"	"10"	"19"	"35"	"19"	"2752"	"299.4"	"12.06"	"5436.53"	"68.77"	"14"	"19"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf08312"	"23524"	"ENSG00000167978"	"SRRM2"	"A6NKB9; D3DU97; hsa:23524; O15038; O94803; Q6NSL3; Q6PIM3; Q6PK40; Q8IW17; Q96GY7; Q9P0G1; Q9UHA8; Q9UQ35; Q9UQ36; Q9UQ37; Q9UQ38; Q9UQ40"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"1325.7"	"795.6"	"1051.7"	"941.6"	"1051.2"	"1252.4"	"3078.9"	"2393.4"	"1904.9"	"3760.0"	"4750.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UQ80"	"Proliferation-associated protein 2G4 OS=Homo sapiens OX=9606 GN=PA2G4 PE=1 SV=3"	"52"	"18"	"42"	"18"	"394"	"43.8"	"6.55"	"8352.78"	"68.57"	"17"	"15"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00557"	"5036"	"ENSG00000170515"	"PA2G4"	"hsa:5036; O43846; Q9UM59; Q9UQ80"	""	"Neutrophil degranulation"	"1"	"0"	"1266.8"	"846.2"	"1436.4"	"1297.1"	"1497.2"	"1418.2"	"4322.2"	"3994.8"	"2793.0"	"4390.3"	"6427.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11021"	"Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2"	"41"	"24"	"44"	"21"	"654"	"72.3"	"5.16"	"8341.67"	"68.47"	"18"	"22"	"protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;nucleus;other cell component"	"translation activity;other molecular function"	"Pf00012"	"3309"	"ENSG00000044574"	"HSPA5"	"B0QZ61; hsa:3309; P11021; Q2EF78; Q9NPF1; Q9UK02"	"Parkin-ubiquitin proteasomal system pathway; Apoptosis-related network due to altered Notch3 in ovarian cancer; Photodynamic therapy-induced unfolded protein response; Prion disease pathway; Unfolded protein response; Orexin receptor pathway"	"Regulation of HSF1-mediated heat shock response; Platelet degranulation ; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; ATF6B (ATF6-beta) activates chaperones; IRE1alpha activates chaperones; PERK regulates gene expression; ATF6 (ATF6-alpha) activates chaperone genes"	"14"	"0"	"1900.4"	"1101.7"	"1772.9"	"1593.9"	"1649.4"	"1760.7"	"2863.0"	"2567.7"	"1856.0"	"3106.0"	"4707.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q06830"	"Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1"	"52"	"13"	"44"	"9"	"199"	"22.1"	"8.13"	"8079.05"	"68.02"	"13"	"12"	"cell cycle OR cell proliferation;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00578, Pf10417"	"5052"	"ENSG00000117450"	"PRDX1"	"B5BU26; D3DPZ8; hsa:5052; P35703; Q06830; Q2V576; Q5T154; Q5T155"	"Androgen receptor signaling pathway; Selenium micronutrient network; Nuclear receptors meta-pathway; NRF2 pathway"	"Detoxification of Reactive Oxygen Species; TP53 Regulates Metabolic Genes; NFE2L2 regulating anti-oxidant/detoxification enzymes; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"	"8"	"6"	"2870.3"	"1572.2"	"2143.3"	"2192.1"	"1956.1"	"2485.9"	"4059.6"	"3838.6"	"3438.9"	"4435.3"	"6246.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62318"	"Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1"	"56"	"7"	"34"	"7"	"126"	"13.9"	"10.32"	"7827.63"	"67.13"	"5"	"5"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01423"	"6634"	"ENSG00000100028"	"SNRPD3"	"B4DJP7; B5BU13; hsa:6634; P43331; P62318"	"mRNA processing"	"mRNA Splicing - Major Pathway; RNA Polymerase II Transcription Termination; SARS-CoV-2 modulates host translation machinery; snRNP Assembly; mRNA Splicing - Minor Pathway; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"8"	"0"	"1093.7"	"879.9"	"1377.1"	"963.5"	"1127.6"	"1004.8"	"2754.1"	"2429.8"	"1773.4"	"2690.3"	"3369.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94832"	"Unconventional myosin-Id OS=Homo sapiens OX=9606 GN=MYO1D PE=1 SV=2"	"16"	"15"	"35"	"15"	"1006"	"116.1"	"9.39"	"5877.07"	"66.12"	"12"	"14"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00063, Pf00612, Pf06017"	"4642"	"ENSG00000176658"	"MYO1D"	"A6H8V3; hsa:4642; O94832; Q8NHP9"	""	""	"0"	"0"	"448.2"	"296.6"	"498.1"	"437.3"	"485.8"	"537.3"	"1154.3"	"1288.9"	"1601.0"	"3422.5"	"5199.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00367"	"Glutamate dehydrogenase 1, mitochondrial OS=Homo sapiens OX=9606 GN=GLUD1 PE=1 SV=2"	"35"	"16"	"41"	"16"	"558"	"61.4"	"7.80"	"6941.82"	"65.79"	"14"	"15"	"other metabolic processes;other biological processes"	"mitochondrion;ER/Golgi;other cell component"	"other molecular function"	"Pf00208, Pf02812"	"2746"	"ENSG00000148672"	"GLUD1"	"B3KV55; B4DGN5; hsa:2746; P00367; Q5TBU3"	"VEGFA-VEGFR2 signaling; Amino acid metabolism; Metabolic reprogramming in colon cancer; 22q11.2 copy number variation syndrome; Amino acid metabolism pathway excerpt: histidine catabolism extension; 10q22q23 copy number variation"	"Transcriptional activation of mitochondrial biogenesis; Glutamate and glutamine metabolism"	"8"	"0"	"3433.9"	"1912.3"	"2990.7"	"2644.5"	"3010.2"	"2704.8"	"3859.9"	"3475.0"	"2436.5"	"3835.0"	"5825.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14678"	"Small nuclear ribonucleoprotein-associated proteins B and B' OS=Homo sapiens OX=9606 GN=SNRPB PE=1 SV=2"	"25"	"8"	"32"	"8"	"240"	"24.6"	"11.19"	"4148.76"	"65.59"	"6"	"8"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01423"	"6628"	"ENSG00000125835"	"SNRPB"	"hsa:6628; P14678; Q15490; Q6IB35; Q9UIS5"	"mRNA processing"	"snRNP Assembly; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; SARS-CoV-2 modulates host translation machinery; mRNA Splicing - Minor Pathway; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"8"	"0"	"1413.4"	"986.2"	"1314.1"	"1089.7"	"1216.6"	"1070.7"	"2754.9"	"2585.9"	"1859.2"	"2971.4"	"4091.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12956"	"X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2"	"33"	"19"	"42"	"19"	"609"	"69.8"	"6.64"	"6962.90"	"65.53"	"16"	"16"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02037, Pf02735, Pf03730, Pf03731"	"2547"	"ENSG00000196419"	"XRCC6"	"B1AHC8; hsa:2547; P12956; Q6FG89; Q9UCQ2; Q9UCQ3"	"Non-homologous end joining; DNA repair pathways, full network; Primary ovarian insufficiency"	"Neutrophil degranulation; Cytosolic sensors of pathogen-associated DNA ; Nonhomologous End-Joining (NHEJ); 2-LTR circle formation; IRF3-mediated induction of type I IFN"	"8"	"0"	"1895.7"	"1014.4"	"1536.9"	"1354.8"	"1573.0"	"1488.8"	"3949.1"	"3491.5"	"2292.8"	"3915.5"	"5439.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P38159"	"RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX PE=1 SV=3"	"36"	"12"	"45"	"5"	"391"	"42.3"	"10.05"	"8263.56"	"65.41"	"11"	"11"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08081"	"27316"	"ENSG00000147274"	"RBMX"	"B4E3U4; D3DWH0; E9PG86; hsa:27316; P38159; Q5JQ67; Q8N8Y7; Q969R3"	"mRNA processing"	"mRNA Splicing - Major Pathway; RND2 GTPase cycle; RND3 GTPase cycle; RND1 GTPase cycle; Processing of Capped Intron-Containing Pre-mRNA; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle"	"8"	"7"	"2665.1"	"1784.1"	"2099.1"	"1787.9"	"2207.4"	"2460.0"	"4992.5"	"3836.0"	"2978.4"	"5545.1"	"6718.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25205"	"DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3"	"26"	"20"	"40"	"20"	"808"	"90.9"	"5.77"	"6790.62"	"65.34"	"18"	"18"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855"	"4172"	"ENSG00000112118"	"MCM3"	"B4DWW4; hsa:4172; P25205; Q92660; Q9BTR3; Q9NUE7"	"Cell cycle; Retinoblastoma gene in cancer; Ciliary landscape; G1 to S cell cycle control; DNA replication"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"11"	"0"	"1288.4"	"876.5"	"1295.1"	"1180.1"	"1253.4"	"1438.9"	"3707.3"	"3435.4"	"2431.1"	"3430.6"	"4324.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P36578"	"60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5"	"40"	"16"	"39"	"15"	"427"	"47.7"	"11.06"	"6954.63"	"65.09"	"16"	"12"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00573, Pf14374"	"6124"	"ENSG00000174444"	"RPL4"	"A8K502; hsa:6124; P36578; P39029; Q4VBR0; Q969Z9"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"1"	"1700.7"	"1113.2"	"1408.9"	"1226.0"	"1397.4"	"1524.3"	"4878.5"	"4577.3"	"3172.6"	"5105.5"	"6618.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61981"	"14-3-3 protein gamma OS=Homo sapiens OX=9606 GN=YWHAG PE=1 SV=2"	"45"	"12"	"43"	"7"	"247"	"28.3"	"4.89"	"7846.73"	"65.01"	"11"	"12"	"transport;signal transduction;other biological processes"	"cytosol;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00244"	"7532"	"ENSG00000170027"	"YWHAG"	"hsa:7532; O70457; P35214; P61981; Q6FH52; Q9UDP2; Q9UN99"	"Cell cycle; Prolactin signaling pathway; Myometrial relaxation and contraction pathways; Disruption of postsynaptic signaling by CNV; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Regulation of localization of FOXO transcription factors; TP53 Regulates Metabolic Genes; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Activation of BAD and translocation to mitochondria"	"21"	"0"	"687.8"	"394.9"	"570.7"	"641.9"	"614.6"	"687.1"	"1264.3"	"1183.3"	"910.5"	"1290.8"	"1717.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09661"	"U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2"	"67"	"20"	"48"	"20"	"255"	"28.4"	"8.62"	"8948.93"	"63.83"	"18"	"16"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf14580"	"6627"	"ENSG00000131876"	"SNRPA1"	"B2R5I6; hsa:6627; P09661; Q8TBD2"	"mRNA processing"	"mRNA Splicing - Major Pathway; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"3"	"0"	"3673.3"	"2506.3"	"2931.5"	"2548.5"	"2733.0"	"2573.2"	"5872.7"	"5397.4"	"4196.1"	"6101.0"	"8739.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15371"	"Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1"	"30"	"14"	"28"	"14"	"548"	"63.9"	"6.05"	"3513.40"	"63.82"	"8"	"14"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf05091"	"8664"	"ENSG00000100353"	"EIF3D"	"A8MWD3; B2R7D4; B4DTF8; B4DVY1; hsa:8664; O15371; Q3MJD9; Q5M9Q6"	"Translation factors; VEGFA-VEGFR2 signaling; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"9"	"0"	"919.1"	"612.3"	"945.9"	"856.7"	"998.3"	"928.6"	"2142.9"	"1992.8"	"1408.1"	"2115.5"	"2470.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12905"	"Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2"	"44"	"11"	"22"	"11"	"390"	"43.0"	"5.26"	"3710.15"	"63.52"	"6"	"9"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf07528"	"3608"	"ENSG00000143621"	"ILF2"	"A6NDB0; B2R8G7; hsa:3608; Q12905; Q5SR10; Q5SR11; Q7L7R3; Q9BWD4; Q9P1N0"	"B cell receptor signaling pathway"	"Neutrophil degranulation"	"2"	"0"	"1597.5"	"984.4"	"1291.4"	"1024.3"	"1278.0"	"1342.3"	"2649.8"	"2254.1"	"1705.0"	"2794.7"	"3725.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14697"	"Neutral alpha-glucosidase AB OS=Homo sapiens OX=9606 GN=GANAB PE=1 SV=3"	"22"	"16"	"37"	"16"	"944"	"106.8"	"6.14"	"5802.58"	"63.28"	"14"	"16"	"protein metabolism;other metabolic processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf01055, Pf13802"	"23193"	"ENSG00000089597"	"GANAB"	"A6NC20; hsa:23193; Q14697; Q8WTS9; Q9P0X0"	"N-glycan biosynthesis"	"Maturation of spike protein; Calnexin/calreticulin cycle; Maturation of spike protein"	"5"	"0"	"1247.9"	"800.8"	"1271.1"	"1105.7"	"1174.8"	"1238.0"	"1730.2"	"1693.6"	"1272.3"	"2085.7"	"3044.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50990"	"T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4"	"34"	"19"	"37"	"19"	"548"	"59.6"	"5.60"	"6516.33"	"62.90"	"17"	"18"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00118"	"10694"	"ENSG00000156261"	"CCT8"	"A6NN54; B4DEM7; B4DQH4; hsa:10694; P50990; Q4VBP8"	"16p11.2 proximal deletion syndrome"	"Neutrophil degranulation; Association of TriC/CCT with target proteins during biosynthesis; Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"8"	"0"	"2556.3"	"1801.3"	"2680.7"	"2094.6"	"2441.4"	"2529.8"	"3268.1"	"2994.7"	"2245.8"	"3593.6"	"5262.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00558"	"Phosphoglycerate kinase 1 OS=Homo sapiens OX=9606 GN=PGK1 PE=1 SV=3"	"43"	"15"	"26"	"15"	"417"	"44.6"	"8.10"	"4100.65"	"62.75"	"8"	"13"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;other membranes;cytosol"	"kinase activity;other molecular function"	"Pf00162"	"5230"	"ENSG00000102144"	"PGK1"	"A8K4W6; B7Z7A9; hsa:5230; P00558; Q5J7W1; Q6IBT6; Q8NI87"	"Cori cycle; Photodynamic therapy-induced HIF-1 survival signaling; VEGFA-VEGFR2 signaling; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; Glycolysis in senescence; Warburg effect modulated by deubiquitinating enzymes and their substrates; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"Glycolysis; Gluconeogenesis; Manipulation of host energy metabolism"	"13"	"0"	"853.0"	"603.7"	"906.7"	"587.2"	"767.6"	"832.5"	"1089.4"	"1077.6"	"1248.8"	"3534.7"	"11582.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P54652"	"Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1"	"21"	"14"	"41"	"1"	"639"	"70.0"	"5.74"	"6440.91"	"62.68"	"12"	"13"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00012"	"3306"	"ENSG00000126803"	"HSPA2"	"hsa:3306; P54652; Q15508; Q53XM3; Q9UE78"	"Parkin-ubiquitin proteasomal system pathway; MAPK signaling pathway; Measles virus infection; 7q11.23 copy number variation syndrome; Urotensin-II-mediated signaling pathway"	"Meiotic synapsis; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Regulation of HSF1-mediated heat shock response; Attenuation phase"	"9"	"0"	"83.6"	"66.8"	"82.9"	"75.6"	"49.8"	"121.0"	"130.6"	"112.5"	"85.3"	"124.7"	"233.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14980"	"Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2"	"10"	"18"	"34"	"18"	"2115"	"238.1"	"5.78"	"5646.96"	"62.50"	"14"	"17"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	""	"4926"	"ENSG00000137497"	"NUMA1"	"H0YH75; hsa:4926; Q14980; Q14981; Q9BTE9"	"Ectoderm differentiation; Ectoderm differentiation; 8p23.1 copy number variation syndrome"	"Recruitment of NuMA to mitotic centrosomes; Mitotic Prophase"	"5"	"0"	"1189.9"	"724.2"	"935.2"	"983.2"	"1108.1"	"1171.2"	"2039.6"	"1847.7"	"1319.1"	"2369.7"	"2860.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P17987"	"T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1"	"38"	"16"	"33"	"16"	"556"	"60.3"	"6.11"	"7084.08"	"62.50"	"14"	"15"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf00118"	"6950"	"ENSG00000120438"	"TCP1"	"E1P5B2; hsa:6950; P17987; Q15556; Q5TCM3"	"16p11.2 proximal deletion syndrome"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"8"	"0"	"1577.6"	"1016.3"	"1631.4"	"1399.2"	"1561.0"	"1627.5"	"2240.7"	"1994.4"	"1381.2"	"2311.4"	"3244.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09651"	"Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5"	"38"	"13"	"48"	"10"	"372"	"38.7"	"9.13"	"10028.32"	"61.91"	"11"	"9"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf11627"	"3178"	"ENSG00000135486"	"HNRNPA1"	"A8K4Z8; hsa:3178; P09651; Q3MIB7; Q6PJZ7"	"mRNA processing"	"mRNA Splicing - Major Pathway; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA; SARS-CoV-1-host interactions; SARS-CoV-1 modulates host translation machinery"	"6"	"0"	"2400.9"	"1835.6"	"1941.6"	"2042.3"	"2024.4"	"2167.8"	"4382.7"	"4040.2"	"3283.5"	"4846.6"	"5491.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63244"	"Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3"	"44"	"15"	"40"	"15"	"317"	"35.1"	"7.69"	"7477.65"	"61.62"	"15"	"15"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;cytosol;mitochondrion;translational apparatus;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;translation activity;other molecular function"	"Pf00400"	"10399"	"ENSG00000204628"	"RACK1"	"B3KTJ0; D3DWS0; hsa:10399; P25388; P63244; P99049; Q53HU2; Q5J8M6; Q5VLR4; Q6FH47"	"Androgen receptor signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; VEGFA-VEGFR2 signaling; Measles virus infection; Angiotensin II receptor type 1 pathway; TROP2 regulatory signaling; Interferon type I signaling pathways"	"Regulation of TNFR1 signaling; TNFR1-induced NF-kappa-B signaling pathway; TNFR1-mediated ceramide production"	"10"	"0"	"2357.3"	"1542.4"	"2527.7"	"1590.6"	"2042.6"	"1898.1"	"5290.5"	"4849.5"	"3320.8"	"5255.2"	"6834.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P27695"	"DNA-(apurinic or apyrimidinic site) lyase OS=Homo sapiens OX=9606 GN=APEX1 PE=1 SV=2"	"42"	"11"	"32"	"11"	"318"	"35.5"	"8.12"	"5918.23"	"61.42"	"11"	"11"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;mitochondrion;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03372"	"328"	"ENSG00000100823"	"APEX1"	"hsa:328; P27695; Q969L5; Q99775"	"Thyroid stimulating hormone (TSH) signaling pathway; Spinal cord injury; Base excision repair; DNA repair pathways, full network"	"Displacement of DNA glycosylase by APEX1; POLB-Dependent Long Patch Base Excision Repair; PCNA-Dependent Long Patch Base Excision Repair; Abasic sugar-phosphate removal via the single-nucleotide replacement pathway"	"10"	"0"	"365.9"	"219.9"	"364.0"	"427.0"	"468.6"	"516.3"	"2985.0"	"2783.8"	"2173.2"	"3326.0"	"5093.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26641"	"Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3"	"33"	"16"	"42"	"16"	"437"	"50.1"	"6.67"	"7037.48"	"61.30"	"15"	"14"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity"	"Pf00043, Pf00647, Pf02798"	"1937"	"ENSG00000254772"	"EEF1G"	"B4DTG2; hsa:1937; P26641; Q6PJ62; Q6PK31; Q96CU2; Q9P196"	"Translation factors"	"Signaling by ALK fusions and activated point mutants; Eukaryotic Translation Elongation"	"3"	"0"	"2613.9"	"1291.6"	"2052.5"	"2699.0"	"2208.4"	"2962.2"	"5748.4"	"5753.5"	"4141.9"	"5864.9"	"7621.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92499"	"ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2"	"25"	"14"	"29"	"14"	"740"	"82.4"	"7.23"	"5401.18"	"61.04"	"12"	"14"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf00622"	"1653"	"ENSG00000079785"	"DDX1"	"B4DME8; B4DPN6; hsa:1653; Q92499"	"DDX1 as a regulatory component of the Drosha microprocessor; mRNA processing"	"tRNA processing in the nucleus"	"3"	"0"	"624.2"	"393.1"	"575.8"	"508.7"	"594.6"	"545.5"	"1506.0"	"1340.7"	"988.1"	"1679.5"	"2256.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2W1"	"Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2"	"20"	"19"	"39"	"19"	"955"	"108.6"	"10.15"	"7299.59"	"60.97"	"18"	"16"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf15440"	"9967"	"ENSG00000054118"	"THRAP3"	"D3DPS5; hsa:9967; Q5VTK6; Q9Y2W1"	"Interactome of polycomb repressive complex 2 (PRC2)"	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation"	"3"	"0"	"1911.1"	"1283.4"	"1442.6"	"1392.8"	"1563.8"	"1667.3"	"4394.1"	"3665.3"	"2845.5"	"4565.4"	"5501.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NSD9"	"Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3"	"31"	"19"	"40"	"19"	"589"	"66.1"	"6.84"	"6946.69"	"60.89"	"16"	"18"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03483, Pf03484, Pf17759, Pf18262"	"10056"	"ENSG00000116120"	"FARSB"	"B4DFM0; hsa:10056; O95708; Q4ZFX1; Q57ZJ5; Q9NSD9; Q9NZZ6"	"VEGFA-VEGFR2 signaling; Amino acid metabolism"	"Cytosolic tRNA aminoacylation"	"3"	"0"	"1040.4"	"707.4"	"1038.4"	"921.3"	"1126.4"	"1043.2"	"4807.6"	"4444.6"	"3039.8"	"4836.5"	"5817.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30876"	"DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1"	"17"	"18"	"35"	"18"	"1174"	"133.8"	"6.87"	"6884.08"	"60.72"	"17"	"16"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00562, Pf04560, Pf04561, Pf04563, Pf04565, Pf04566, Pf04567"	"5431"	"ENSG00000047315"	"POLR2B"	"A8K1A8; hsa:5431; P30876; Q8IZ61"	"Pyrimidine metabolism; Eukaryotic transcription initiation"	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; mRNA Splicing - Major Pathway; PIWI-interacting RNA (piRNA) biogenesis; mRNA Splicing - Minor Pathway; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"43"	"0"	"1396.1"	"879.8"	"1101.1"	"1098.4"	"1157.8"	"1137.2"	"2449.7"	"2399.7"	"1928.5"	"2880.4"	"3284.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26599"	"Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1"	"39"	"15"	"37"	"13"	"531"	"57.2"	"9.17"	"6994.60"	"60.62"	"10"	"13"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf11835, Pf13893"	"749887"	"ENSPPYG00000009289; ENSPTRG00000010165"	"PTBP1"	"A0A2J8IKP3; A0A2J8RA51; A0A6D2WFY9; A0A8I5YPF9; K7AXA8"	""	""	"0"	"4"	"1746.6"	"953.5"	"1333.5"	"1325.8"	"1365.4"	"1523.9"	"4245.8"	"4129.7"	"3394.5"	"4385.0"	"5906.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01105"	"Protein SET OS=Homo sapiens OX=9606 GN=SET PE=1 SV=3"	"29"	"9"	"32"	"9"	"290"	"33.5"	"4.32"	"6030.88"	"59.79"	"8"	"8"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00956"	"6418"	"ENSG00000119335"	"SET"	"A5A5H4; A6NGV1; B4DUE2; hsa:6418; Q01105; Q15541; Q5VXV1; Q5VXV2; Q6FHZ5"	"Histone modifications; VEGFA-VEGFR2 signaling"	"HuR (ELAVL1) binds and stabilizes mRNA; Condensation of Prophase Chromosomes"	"4"	"0"	"925.2"	"594.1"	"860.8"	"748.6"	"799.7"	"846.0"	"3781.5"	"3387.7"	"2425.1"	"3200.7"	"4263.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q1KMD3"	"Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1"	"24"	"17"	"33"	"17"	"747"	"85.1"	"4.91"	"4566.40"	"59.53"	"13"	"17"	""	"nucleus;other cell component"	""	"Pf00622, Pf02037, Pf13671"	"221092"	"ENSG00000214753"	"HNRNPUL2"	"hsa:221092; Q1KMD3; Q8N3B3"	""	""	"0"	"0"	"2854.8"	"2125.4"	"3280.9"	"2399.4"	"2768.9"	"2959.7"	"3595.0"	"3037.3"	"2133.8"	"3863.6"	"5527.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31942"	"Heterogeneous nuclear ribonucleoprotein H3 OS=Homo sapiens OX=9606 GN=HNRNPH3 PE=1 SV=2"	"36"	"10"	"29"	"9"	"346"	"36.9"	"6.87"	"4649.67"	"59.45"	"6"	"10"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00076"	"3189"	"ENSG00000096746"	"HNRNPH3"	"A8K682; B3KRE1; hsa:3189; P31942; Q9BSX1; Q9NP53; Q9NP96; Q9NPA7; Q9NPI4; Q9UFU4; Q9Y4J5"	""	""	"0"	"0"	"1071.7"	"639.5"	"845.9"	"853.6"	"1007.8"	"1056.9"	"1730.6"	"1634.3"	"1261.8"	"1951.2"	"2311.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53396"	"ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3"	"20"	"19"	"39"	"19"	"1101"	"120.8"	"7.33"	"7592.00"	"58.45"	"17"	"14"	"other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00285, Pf00549, Pf02629, Pf16114"	"47"	"ENSG00000131473"	"ACLY"	"B4DIM0; B4E3P0; hsa:47; P53396; Q13037; Q9BRL0"	"Sterol regulatory element-binding proteins (SREBP) signaling; TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Fatty acid biosynthesis; Amino acid metabolism; Lipid metabolism pathway; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer"	"Neutrophil degranulation; ChREBP activates metabolic gene expression; Fatty acyl-CoA biosynthesis"	"10"	"0"	"1853.3"	"1153.3"	"1723.8"	"1375.5"	"1685.1"	"1746.3"	"2899.8"	"2744.8"	"2060.1"	"3107.5"	"4417.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13435"	"Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2"	"19"	"19"	"38"	"19"	"895"	"100.2"	"5.67"	"7762.50"	"58.20"	"18"	"15"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf02037, Pf04037, Pf04046"	"10992"	"ENSG00000087365"	"SF3B2"	"A8K485; B4DT19; hsa:10992; Q13435; Q7L4T5; Q7Z627; Q969K1; Q96CM6; Q9BWD2"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"0"	"2253.4"	"1161.2"	"1668.5"	"1427.8"	"1742.4"	"1614.6"	"3907.5"	"3445.8"	"2363.6"	"4252.3"	"5993.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31948"	"Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1"	"29"	"15"	"34"	"15"	"543"	"62.6"	"6.80"	"6154.50"	"58.09"	"15"	"15"	"other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00515, Pf13181, Pf17830"	"10963"	"ENSG00000168439"	"STIP1"	"B4DM70; F5H0T1; G3XAD8; hsa:10963; P31948; Q3ZCU9; Q5TZU9"	"VEGFA-VEGFR2 signaling"	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; RND1 GTPase cycle"	"3"	"0"	"1592.0"	"845.0"	"1217.5"	"1336.3"	"1177.1"	"1484.4"	"2641.4"	"2281.7"	"1745.8"	"2834.9"	"4021.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P34932"	"Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4"	"28"	"21"	"38"	"19"	"840"	"94.3"	"5.19"	"7298.22"	"57.92"	"18"	"18"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport"	"non-structural extracellular;cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf00012"	"3308"	"ENSG00000170606"	"HSPA4"	"hsa:3308; O95756; P34932; Q2TAL4; Q9BUK9"	"Parkin-ubiquitin proteasomal system pathway"	"Regulation of HSF1-mediated heat shock response"	"2"	"2"	"2704.8"	"1478.4"	"2404.2"	"2056.7"	"2134.7"	"2341.8"	"3506.4"	"3063.3"	"2258.0"	"3544.1"	"5175.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P99999"	"Cytochrome c OS=Homo sapiens OX=9606 GN=CYCS PE=1 SV=2"	"62"	"8"	"39"	"8"	"105"	"11.7"	"9.57"	"7769.53"	"57.89"	"8"	"6"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"other membranes;cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf00034"	"54205"	"ENSG00000172115"	"CYCS"	"A4D166; B2R4I1; hsa:54205; P00001; P99999; Q6NUR2; Q6NX69; Q96BV4"	"miRNA regulation of DNA damage response; Apoptosis modulation and signaling; Alzheimer's disease and miRNA effects; AGE/RAGE pathway; Parkinson's disease pathway; Nanomaterial induced apoptosis; Apoptosis; Fas ligand pathway and stress induction of heat shock proteins; Apoptosis modulation by HSP70; VEGFA-VEGFR2 signaling; Oxidative damage response; NO/cGMP/PKG mediated neuroprotection; Chromosomal and microsatellite instability in colorectal cancer ; Non-small cell lung cancer; Acute viral myocarditis; Nonalcoholic fatty liver disease; Measles virus infection; Small cell lung cancer; Hepatitis B infection; IL-18 signaling pathway; Pleural mesothelioma; Complement system in neuronal development and plasticity; Alzheimer's disease; DNA damage response"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1; Detoxification of Reactive Oxygen Species; Transcriptional activation of mitochondrial biogenesis; Activation of caspases through apoptosome-mediated cleavage; SMAC (DIABLO) binds to IAPs ; SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes ; Regulation of the apoptosome activity; Release of apoptotic factors from the mitochondria; Pyroptosis"	"36"	"0"	"574.3"	"356.0"	"569.0"	"588.3"	"718.3"	"637.5"	"6310.2"	"6023.7"	"5752.8"	"7929.8"	"10265.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49407"	"Beta-arrestin-1 OS=Homo sapiens OX=9606 GN=ARRB1 PE=1 SV=2"	"40"	"15"	"31"	"13"	"418"	"47.0"	"6.20"	"5376.90"	"57.54"	"11"	"14"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00339, Pf02752"	"408"	"ENSG00000137486"	"ARRB1"	"B6V9G8; hsa:408; O75625; O75630; P49407; Q2PP20; Q9BTK8"	"Corticotropin-releasing hormone signaling pathway; Myometrial relaxation and contraction pathways; MAPK signaling pathway; Chemokine signaling pathway; Hedgehog signaling pathway; Gastrin signaling pathway; Kisspeptin/kisspeptin receptor system in the ovary; GPR143 in melanocytes and retinal pigment epithelium cells; Calcium regulation in cardiac cells"	"Ub-specific processing proteases; Activation of SMO; Activated NOTCH1 Transmits Signal to the Nucleus; G alpha (s) signalling events; Lysosome Vesicle Biogenesis; Golgi Associated Vesicle Biogenesis; Signaling by BRAF and RAF1 fusions; Thrombin signalling through proteinase activated receptors (PARs); Cargo recognition for clathrin-mediated endocytosis; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants"	"25"	"0"	"92.9"	"66.5"	"107.5"	"123.5"	"99.0"	"182.7"	"625.0"	"1236.8"	"1536.7"	"2674.0"	"3641.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P27348"	"14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1"	"40"	"9"	"33"	"6"	"245"	"27.7"	"4.78"	"6437.97"	"57.07"	"8"	"9"	"transport;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00244"	"10971"	"ENSG00000134308"	"YWHAQ"	"D6W4Z5; hsa:10971; P27348; Q567U5; Q5TZU8; Q9UP48"	"Cell cycle; Pathogenic Escherichia coli infection; Primary focal segmental glomerulosclerosis (FSGS); IL-3 signaling pathway; Myometrial relaxation and contraction pathways; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-YAP signaling; Leukocyte-intrinsic Hippo pathway functions; Hepatitis B infection; Opioid receptor pathways; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Regulation of localization of FOXO transcription factors; TP53 Regulates Metabolic Genes; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Activation of BAD and translocation to mitochondria"	"20"	"0"	"424.5"	"247.6"	"390.4"	"398.8"	"396.1"	"425.5"	"594.0"	"587.5"	"433.6"	"700.0"	"927.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60891"	"Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2"	"46"	"14"	"38"	"8"	"318"	"34.8"	"6.98"	"7359.67"	"57.05"	"12"	"12"	"other metabolic processes;developmental processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf13793, Pf14572"	"5631"	"ENSG00000147224"	"PRPS1"	"B1ALA8; B2R6T7; B4DNL6; D3DUX6; hsa:5631; P09329; P60891"	""	"5-Phosphoribose 1-diphosphate biosynthesis"	"1"	"11"	"1893.3"	"1161.0"	"1537.9"	"1769.4"	"1580.0"	"1870.4"	"2553.9"	"2892.9"	"2372.6"	"2769.8"	"2892.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UMS4"	"Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1"	"35"	"12"	"27"	"12"	"504"	"55.1"	"6.61"	"4150.91"	"56.69"	"9"	"12"	"cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00400, Pf04564, Pf08606"	"27339"	"ENSG00000110107"	"PRPF19"	"hsa:27339; Q9UMS4"	""	"mRNA Splicing - Major Pathway; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of TC-NER Pre-Incision Complex"	"5"	"0"	"978.0"	"583.6"	"997.5"	"952.3"	"881.4"	"875.8"	"2165.1"	"2390.8"	"1625.4"	"2691.3"	"5052.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13523"	"Serine/threonine-protein kinase PRP4 homolog OS=Homo sapiens OX=9606 GN=PRPF4B PE=1 SV=3"	"14"	"12"	"31"	"11"	"1007"	"116.9"	"10.26"	"6212.03"	"56.53"	"11"	"12"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"8899"	"ENSG00000112739"	"PRPF4B"	"A8K5C9; hsa:8899; Q13523; Q5D0F6; Q5TAY8; Q8IVC3; Q8TDP2; Q96QT7; Q9UEE6"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"1"	"630.0"	"391.5"	"574.9"	"470.9"	"603.4"	"647.3"	"2472.7"	"2161.4"	"1918.0"	"3738.8"	"5525.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96DI7"	"U5 small nuclear ribonucleoprotein 40 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP40 PE=1 SV=1"	"43"	"11"	"22"	"11"	"357"	"39.3"	"8.10"	"3946.01"	"56.29"	"7"	"11"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf00400"	"9410"	"ENSG00000060688"	"SNRNP40"	"B4DQJ1; hsa:9410; O75938; O95320; Q96DI7"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"0"	"702.0"	"447.4"	"649.4"	"558.1"	"638.8"	"636.1"	"1658.7"	"1639.1"	"1394.1"	"2537.3"	"3983.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P24928"	"DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2"	"12"	"18"	"34"	"18"	"1970"	"217.0"	"7.37"	"6683.12"	"56.14"	"16"	"14"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00623, Pf04983, Pf04990, Pf04992, Pf04997, Pf04998, Pf05000, Pf05001"	"5430"	""	"POLR2A"	"A6NN93; B9EH88; hsa:5430; P24928; Q6NX41"	"Pyrimidine metabolism; Eukaryotic transcription initiation; mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"44"	"0"	"1199.9"	"746.2"	"1154.8"	"1005.9"	"1076.7"	"1116.9"	"2158.8"	"2091.0"	"1531.5"	"2327.9"	"2983.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q07666"	"KH domain-containing, RNA-binding, signal transduction-associated protein 1 OS=Homo sapiens OX=9606 GN=KHDRBS1 PE=1 SV=1"	"20"	"10"	"33"	"10"	"443"	"48.2"	"8.66"	"7464.80"	"55.96"	"9"	"8"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf16274, Pf16568"	"10657"	"ENSG00000121774"	"KHDRBS1"	"D3DPP3; hsa:10657; Q07666; Q6PJX7; Q8NB97; Q99760"	"Leptin signaling pathway; Primary ovarian insufficiency"	"PTK6 Regulates Proteins Involved in RNA Processing"	"3"	"0"	"2465.2"	"1496.8"	"1789.4"	"1783.1"	"1884.1"	"1774.5"	"3745.9"	"3548.9"	"2941.7"	"4008.4"	"5241.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43684"	"Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1"	"40"	"13"	"36"	"13"	"328"	"37.1"	"6.84"	"7263.40"	"55.85"	"13"	"11"	"cell cycle OR cell proliferation;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00400"	"9184"	"ENSG00000154473"	"BUB3"	"A6NJ42; B2R6E7; D3DRE9; hsa:9184; O43684; O43685"	"Cell cycle; Regulation of sister chromatid separation at the metaphase-anaphase transition"	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of mitotic proteins; APC-Cdc20 mediated degradation of Nek2A"	"12"	"0"	"2068.9"	"1314.3"	"2006.8"	"1867.1"	"1840.9"	"2001.2"	"4832.6"	"4770.9"	"3656.0"	"5395.9"	"7424.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q93009"	"Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2"	"17"	"14"	"31"	"14"	"1102"	"128.2"	"5.55"	"6496.85"	"55.58"	"13"	"14"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00443, Pf00917, Pf12436, Pf14533"	"7874"	"ENSG00000187555"	"USP7"	"A6NMY8; B7Z815; H0Y3G8; hsa:7874; Q93009"	"Nucleotide excision repair in xeroderma pigmentosum ; Warburg effect modulated by deubiquitinating enzymes and their substrates"	"Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Ub-specific processing proteases; Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Regulation of TP53 Degradation; Formation of TC-NER Pre-Incision Complex; Regulation of PTEN localization"	"10"	"0"	"912.0"	"512.3"	"1010.8"	"881.4"	"839.4"	"983.0"	"1845.2"	"1780.8"	"1272.1"	"1797.5"	"2055.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96PK6"	"RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2"	"24"	"16"	"32"	"16"	"669"	"69.4"	"9.67"	"5825.58"	"55.10"	"14"	"15"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00076"	"100526737; 10432"	"ENSG00000239306"	"RBM14"	"B0LM41; B3KMN4; D6RGD8; hsa:100526737; hsa:10432; O75932; Q2PYN1; Q53GV1; Q68DQ9; Q96PK5; Q96PK6"	"Ciliary landscape"	"RUNX2 regulates bone development"	"2"	"0"	"1238.5"	"850.8"	"1089.2"	"943.3"	"1122.5"	"1169.5"	"3983.9"	"4142.4"	"3361.4"	"4296.9"	"4602.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00267"	"Transcription elongation factor SPT5 OS=Homo sapiens OX=9606 GN=SUPT5H PE=1 SV=1"	"15"	"16"	"32"	"16"	"1087"	"120.9"	"5.06"	"5869.90"	"55.00"	"14"	"14"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00467, Pf03439, Pf11942"	"6829"	"ENSG00000196235"	"SUPT5H"	"hsa:6829; O00267; O43279; Q59G52; Q99639"	"Initiation of transcription and translation elongation at the HIV-1 LTR; mRNA processing"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE"	"20"	"0"	"2243.0"	"1335.0"	"1962.4"	"1932.0"	"1874.8"	"2196.3"	"3798.3"	"3356.0"	"2356.3"	"3526.8"	"4732.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96P16"	"Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1"	"55"	"16"	"32"	"14"	"312"	"35.7"	"7.55"	"5471.10"	"54.88"	"12"	"12"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf04818, Pf16566"	"55197"	"ENSG00000141425"	"RPRD1A"	"A8KA42; B2RBA3; hsa:55197; Q7Z5G8; Q96FY9; Q96P16; Q9NVL4"	""	"RNA polymerase II transcribes snRNA genes"	"1"	"1"	"627.1"	"399.9"	"649.1"	"679.5"	"733.2"	"808.0"	"3895.6"	"4043.2"	"3104.5"	"4150.6"	"5276.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13647"	"Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3"	"21"	"15"	"38"	"8"	"590"	"62.3"	"7.74"	"5868.10"	"54.36"	"13"	"14"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;other cell component"	"bone, tooth or skin structural activity;cytoskeletal activity;other molecular function"	"Pf00038, Pf16208"	"3852"	"ENSG00000186081"	"KRT5"	"hsa:3852; P13647; Q6PI71; Q6UBJ0; Q8TA91"	""	"Formation of the cornified envelope; Type I hemidesmosome assembly"	"3"	"1"	"357.9"	"29.4"	"4691.1"	"195.0"	"156.2"	"824.4"	"583.3"	"430.9"	"300.1"	"744.6"	"712.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKV3"	"Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2"	"13"	"18"	"34"	"18"	"1341"	"151.8"	"6.43"	"5908.79"	"54.00"	"15"	"16"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02037, Pf16294"	"22985"	"ENSG00000100813"	"ACIN1"	"B2RTT4; D3DS45; hsa:22985; O75158; Q9UG91; Q9UKV1; Q9UKV2; Q9UKV3"	""	"mRNA Splicing - Major Pathway; Apoptotic cleavage of cellular proteins"	"2"	"0"	"1668.0"	"1082.9"	"1352.5"	"1121.9"	"1522.4"	"1551.2"	"2977.5"	"2554.4"	"2984.3"	"6593.0"	"9347.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P0DP25"	"Calmodulin-3 OS=Homo sapiens OX=9606 GN=CALM3 PE=1 SV=1"	"44"	"8"	"27"	"8"	"149"	"16.8"	"4.22"	"4455.82"	"53.68"	"7"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;mitochondrion;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf13499"	"801; 805; 808"	"ENSG00000160014"	"CALM3"	"hsa:801; hsa:805; hsa:808; P02593; P0DP25; P62158; P70667; P99014; Q13942; Q53S29; Q61379; Q61380; Q96HK3"	"Physiological and pathological hypertrophy of the heart; MicroRNAs in cardiomyocyte hypertrophy; Alzheimer's disease and miRNA effects; T cell receptor and co-stimulatory signaling; Cardiac hypertrophic response; Myometrial relaxation and contraction pathways; G protein signaling pathways; Ras signaling; Melanoma; Endochondral ossification; Endochondral ossification with skeletal dysplasias; CAMKK2 pathway; Glycogen synthesis and degradation; Neuroinflammation and glutamatergic signaling; Alzheimer's disease; G13 signaling pathway; Calcium regulation in cardiac cells"	""	"17"	"0"	"1022.1"	"720.4"	"884.7"	"976.9"	"931.5"	"974.9"	"2144.3"	"2380.5"	"2279.1"	"3316.1"	"4597.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EK5"	"KIF-binding protein OS=Homo sapiens OX=9606 GN=KIFBP PE=1 SV=1"	"23"	"11"	"24"	"11"	"621"	"71.8"	"5.49"	"4739.79"	"53.55"	"9"	"11"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes"	"cytoskeleton;mitochondrion"	"cytoskeletal activity"	"Pf12309"	"26128"	"ENSG00000198954"	"KIFBP"	"A8K5M8; hsa:26128; Q96EK5; Q9BR89; Q9ULE1; Q9Y428"	""	""	"0"	"0"	"195.7"	"125.7"	"357.9"	"202.3"	"283.3"	"275.7"	"484.6"	"860.9"	"1929.8"	"4142.0"	"5907.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P01116"	"GTPase KRas OS=Homo sapiens OX=9606 GN=KRAS PE=1 SV=1"	"58"	"8"	"22"	"8"	"189"	"21.6"	"6.77"	"3678.39"	"51.89"	"5"	"8"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00071"	"3845"	"ENSG00000133703"	"KRAS"	"A8K8Z5; B0LPF9; hsa:3845; P01116; P01118; Q96D10"	"IL-5 signaling pathway; Alzheimer's disease and miRNA effects; Glioblastoma signaling pathways; RalA downstream regulated genes; TNF-alpha signaling pathway; Oncostatin M signaling pathway; Aryl hydrocarbon receptor pathway; Bladder cancer; Extracellular vesicle-mediated signaling in recipient cells; RAC1/PAK1/p38/MMP2 pathway; G protein signaling pathways; BDNF-TrkB signaling; MAPK signaling pathway; PI3K-AKT-mTOR signaling pathway and therapeutic opportunities in prostate cancer; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Endometrial cancer; PI3K-Akt signaling pathway; Chromosomal and microsatellite instability in colorectal cancer ; MAPK cascade; Ras signaling; Epithelial to mesenchymal transition in colorectal cancer; Non-small cell lung cancer; Breast cancer pathway; Pancreatic adenocarcinoma pathway; Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells; Thermogenesis; Non-genomic actions of 1,25 dihydroxyvitamin D3; EGF/EGFR signaling pathway; Relationship between inflammation, COX-2 and EGFR; Envelope proteins and their potential roles in EDMD physiopathology; Synaptic signaling pathways associated with autism spectrum disorder; Hippo-Merlin signaling dysregulation; Fragile X syndrome; Gastrin signaling pathway; Hepatitis B infection; Head and neck squamous cell carcinoma; Melanoma; EGFR tyrosine kinase inhibitor resistance; Kisspeptin/kisspeptin receptor system in the ovary; MAPK pathway in congenital thyroid cancer; Regulation of actin cytoskeleton; Alzheimer's disease; Autophagy in pancreatic ductal adenocarcinoma; JAK-STAT signaling in the regulation of Beta-cells; ErbB signaling pathway; DNA damage response (only ATM dependent); Serotonin receptor 2 and ELK-SRF/GATA4 signaling"	"Signaling by CSF3 (G-CSF); Signaling by CSF1 (M-CSF) in myeloid cells; RAS processing; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAS GAP mutants; Signaling by RAS GTPase mutants; RUNX3 regulates p14-ARF"	"57"	"0"	"570.2"	"390.3"	"641.6"	"538.9"	"530.9"	"572.8"	"1225.4"	"1288.2"	"1168.1"	"1835.7"	"2528.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P40939"	"Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2"	"25"	"16"	"32"	"16"	"763"	"82.9"	"9.04"	"5441.91"	"51.87"	"14"	"15"	"other metabolic processes;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf00378, Pf00725, Pf02737"	"3030"	"ENSG00000084754"	"HADHA"	"B2R7L4; B4DYP2; hsa:3030; P40939; Q16679; Q53T69; Q53TA2; Q96GT7; Q9UQC5"	"Fatty acid beta-oxidation; Mitochondrial long chain fatty acid beta-oxidation; Valproic acid pathway; Mitochondrial fatty acid oxidation disorders; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Acyl chain remodeling of CL; mitochondrial fatty acid beta-oxidation of unsaturated fatty acids; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of myristoyl-CoA to lauroyl-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA; Beta oxidation of palmitoyl-CoA to myristoyl-CoA"	"13"	"0"	"1669.1"	"1069.2"	"1192.8"	"1120.8"	"1215.8"	"1511.9"	"2925.5"	"2639.3"	"1933.2"	"3346.3"	"4409.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6NSI4"	"RPA-related protein RADX OS=Homo sapiens OX=9606 GN=RADX PE=1 SV=2"	"15"	"11"	"31"	"11"	"855"	"97.5"	"8.41"	"5837.81"	"51.83"	"10"	"11"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf17659"	"55086"	"ENSG00000147231"	"RADX"	"H7BY89; hsa:55086; Q4G0L7; Q5JQS1; Q5JRF9; Q6NSI4; Q6PHY5; Q6PII9; Q6PJU8; Q9H7W5; Q9NWA6"	""	""	"0"	"0"	"463.2"	"282.8"	"456.7"	"395.5"	"437.2"	"443.5"	"1374.2"	"1359.0"	"1111.1"	"1588.9"	"1909.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99613"	"Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1"	"18"	"15"	"31"	"15"	"913"	"105.3"	"5.68"	"5678.57"	"51.78"	"13"	"14"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf01399, Pf05470"	"8663"	"ENSG00000184110"	"EIF3C"	"A8K7Z0; B2RXG3; B4E1D5; H3BRV0; hsa:8663; O00215; Q99613; Q9BW98"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"8"	"0"	"1031.9"	"747.0"	"966.7"	"773.0"	"905.1"	"864.0"	"1853.6"	"1714.9"	"1235.9"	"1822.9"	"2339.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62805"	"Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2"	"57"	"10"	"36"	"10"	"103"	"11.4"	"11.36"	"5706.00"	"51.69"	"9"	"9"	"cell organization and biogenesis;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf15511"	"121504; 554313; 8294; 8359; 8360; 8361; 8362; 8363; 8364; 8365; 8366; 8367; 8368; 8370"	"ENSG00000158406; ENSG00000197061; ENSG00000197238; ENSG00000197837; ENSG00000270276; ENSG00000270882; ENSG00000273542; ENSG00000274618; ENSG00000275126; ENSG00000276180; ENSG00000276966; ENSG00000277157; ENSG00000278637; ENSG00000278705"	"H4C1; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9"	"A2VCL0; hsa:121504; hsa:554313; hsa:8294; hsa:8359; hsa:8360; hsa:8361; hsa:8362; hsa:8363; hsa:8364; hsa:8365; hsa:8366; hsa:8367; hsa:8368; hsa:8370; P02304; P02305; P62805; Q6DRA9; Q6FGB8; Q6NWP7"	"Gastric cancer network 1; Histone modifications; 22q11.2 copy number variation syndrome; Male infertility; Type II interferon signaling"	"Meiotic synapsis; Estrogen-dependent gene expression; HDACs deacetylate histones; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Oxidative Stress Induced Senescence; Senescence-Associated Secretory Phenotype (SASP); RNA Polymerase I Promoter Opening; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; Meiotic recombination; RUNX1 regulates transcription of genes involved in differentiation of HSCs; SUMOylation of chromatin organization proteins; HCMV Late Events; HCMV Early Events; Transcriptional regulation by small RNAs; Amyloid fiber formation; Deposition of new CENPA-containing nucleosomes at the centromere; B-WICH complex positively regulates rRNA expression; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Formation of the beta-catenin:TCF transactivating complex; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Pre-NOTCH Transcription and Translation; RMTs methylate histone arginines; HDMs demethylate histones; PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; HATs acetylate histones; RNA Polymerase I Promoter Escape; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Packaging Of Telomere Ends; Condensation of Prophase Chromosomes; DNA Damage/Telomere Stress Induced Senescence; DNA methylation; Nonhomologous End-Joining (NHEJ); Transcriptional regulation of granulopoiesis"	"50"	"0"	"773.1"	"521.6"	"812.6"	"698.5"	"723.1"	"702.1"	"2451.5"	"2404.3"	"1909.3"	"2918.6"	"3614.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IX12"	"Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2"	"16"	"15"	"34"	"15"	"1150"	"132.7"	"5.76"	"5666.96"	"51.68"	"14"	"14"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02037, Pf14443, Pf14444, Pf19256, Pf19257"	"55749"	"ENSG00000060339"	"CCAR1"	"A0JLT7; A1L4P7; A8K9D4; B4DNP8; B4DRK8; hsa:55749; Q32NE3; Q5EBM3; Q5VUP6; Q6PIZ0; Q6X935; Q8IX12; Q9H8N4; Q9NVA7; Q9NVQ0; Q9NWM6"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"1216.3"	"698.9"	"990.9"	"918.1"	"1123.0"	"1107.1"	"2439.5"	"2301.9"	"1614.0"	"2617.8"	"3750.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12874"	"Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1"	"32"	"13"	"32"	"12"	"501"	"58.8"	"5.38"	"6027.28"	"51.66"	"12"	"10"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf11931, Pf12108, Pf13297, Pf16837"	"10946"	"ENSG00000183431"	"SF3A3"	"D3DPT5; hsa:10946; Q12874; Q15460; Q5VT87"	"Exercise-induced circadian regulation; mRNA processing"	"mRNA Splicing - Major Pathway"	"3"	"1"	"2151.5"	"1229.1"	"1959.8"	"1632.9"	"1884.3"	"1881.0"	"4249.8"	"3880.9"	"2655.5"	"4227.3"	"6068.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NC51"	"Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2"	"40"	"17"	"31"	"17"	"408"	"44.9"	"8.65"	"7045.05"	"51.51"	"16"	"12"	"cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf04774, Pf16174"	"26135"	"ENSG00000142864"	"SERBP1"	"hsa:26135; Q5VU19; Q5VU20; Q5VU22; Q8NC51; Q8WUH0; Q96SE2; Q9BTY3; Q9BUM4; Q9Y367; Q9Y4S3"	"Apoptosis-related network due to altered Notch3 in ovarian cancer"	""	"1"	"0"	"2166.1"	"1104.8"	"1617.0"	"1346.6"	"1642.6"	"1480.4"	"5571.9"	"4909.4"	"3204.2"	"4924.0"	"6808.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q04837"	"Single-stranded DNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SSBP1 PE=1 SV=1"	"53"	"9"	"25"	"9"	"148"	"17.2"	"9.60"	"4056.41"	"51.37"	"6"	"9"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00436"	"6742"	"ENSG00000106028; ENSG00000262771"	"SSBP1"	"hsa:6742; Q04837"	""	"Transcriptional activation of mitochondrial biogenesis"	"1"	"0"	"1007.7"	"700.3"	"981.9"	"934.1"	"981.6"	"1049.2"	"1808.7"	"1740.3"	"1376.4"	"2046.4"	"2620.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48643"	"T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1"	"24"	"14"	"33"	"14"	"541"	"59.6"	"5.66"	"6401.50"	"51.31"	"12"	"13"	"protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00118"	"22948"	"ENSG00000150753"	"CCT5"	"A8JZY8; A8K2X8; B4DYD8; hsa:22948; P48643"	"16p11.2 proximal deletion syndrome"	"Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"7"	"0"	"1952.4"	"1321.7"	"2146.4"	"1764.2"	"2098.2"	"2032.7"	"3005.4"	"2735.8"	"1980.6"	"3196.9"	"4114.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P1J9"	"Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1"	"31"	"16"	"34"	"16"	"531"	"60.5"	"9.61"	"5879.75"	"50.97"	"16"	"16"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf05179, Pf16050"	"79577"	"ENSG00000134371"	"CDC73"	"A6NLZ8; B2RBR2; hsa:79577; Q6P1J9; Q6PK51; Q96A07; Q9H245; Q9H5L7"	"Endoderm differentiation"	"Hedgehog 'on' state; Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events; E3 ubiquitin ligases ubiquitinate target proteins; Formation of the beta-catenin:TCF transactivating complex"	"7"	"0"	"1054.3"	"632.9"	"874.3"	"816.8"	"904.4"	"974.4"	"3941.9"	"3724.7"	"2551.1"	"3810.2"	"5136.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L014"	"Probable ATP-dependent RNA helicase DDX46 OS=Homo sapiens OX=9606 GN=DDX46 PE=1 SV=2"	"17"	"19"	"38"	"19"	"1031"	"117.3"	"9.29"	"7003.15"	"50.85"	"19"	"17"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"other membranes;nucleus"	"other molecular function"	"Pf00270, Pf00271"	"9879"	"ENSG00000145833"	"DDX46"	"hsa:9879; O94894; Q7L014; Q96EI0; Q9Y658"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"1650.6"	"968.8"	"1312.5"	"1252.4"	"1365.1"	"1453.2"	"3259.2"	"2986.5"	"2175.3"	"3517.9"	"5050.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55884"	"Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3"	"23"	"13"	"28"	"13"	"814"	"92.4"	"5.00"	"5140.04"	"50.58"	"11"	"11"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08662"	"8662"	"ENSG00000106263"	"EIF3B"	"A4D208; hsa:8662; P55884; Q2NL77; Q9UMF9"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition"	"8"	"0"	"858.2"	"572.9"	"885.6"	"640.7"	"813.3"	"784.3"	"1596.2"	"1473.2"	"1039.0"	"1674.4"	"2180.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15717"	"ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2"	"32"	"9"	"27"	"9"	"326"	"36.1"	"9.17"	"5101.76"	"50.32"	"8"	"9"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"1994"	"ENSG00000066044"	"ELAVL1"	"B4DVB8; hsa:1994; Q15717; Q53XN6; Q9BTT1"	"AMP-activated protein kinase signaling; Endoderm differentiation; Pre-implantation embryo; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Gastrin signaling pathway; IL-18 signaling pathway; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; 1p36 copy number variation syndrome"	"HuR (ELAVL1) binds and stabilizes mRNA"	"10"	"0"	"1662.3"	"996.3"	"1427.4"	"1055.0"	"1431.0"	"1370.1"	"2252.9"	"1927.5"	"1425.8"	"2575.4"	"3258.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96E39"	"RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1"	"25"	"9"	"34"	"2"	"390"	"42.1"	"9.89"	"5891.04"	"50.05"	"9"	"8"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf08081"	"494115"	"ENSG00000213516"	"RBMXL1"	"hsa:494115; Q96E39"	""	""	"0"	"0"	"216.1"	"134.0"	"156.3"	"132.5"	"178.8"	"179.0"	"339.8"	"289.6"	"237.0"	"414.2"	"528.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00688"	"Peptidyl-prolyl cis-trans isomerase FKBP3 OS=Homo sapiens OX=9606 GN=FKBP3 PE=1 SV=1"	"39"	"12"	"32"	"12"	"224"	"25.2"	"9.28"	"4997.76"	"49.80"	"10"	"11"	""	"nucleus"	"other molecular function"	"Pf00254, Pf18410"	"2287"	"ENSG00000100442"	"FKBP3"	"B2R4Q9; hsa:2287; Q00688; Q14317"	""	""	"0"	"0"	"369.3"	"246.2"	"401.0"	"401.2"	"428.6"	"450.5"	"3398.1"	"3374.9"	"3296.8"	"5464.8"	"9570.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22102"	"Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1"	"17"	"13"	"21"	"13"	"1010"	"107.7"	"6.70"	"2784.50"	"49.58"	"6"	"13"	"other metabolic processes;developmental processes;other biological processes"	"cytosol"	"other molecular function"	"Pf00551, Pf00586, Pf01071, Pf02769, Pf02843, Pf02844"	"2618"	"ENSG00000159131; ENSG00000262473"	"GART"	"A8K945; A8KA32; D3DSF3; D3DSF4; hsa:2618; O14659; P22102; Q52M77"	"Folate metabolism; One-carbon metabolism; Metabolic reprogramming in colon cancer"	"Purine ribonucleoside monophosphate biosynthesis"	"4"	"0"	"234.2"	"137.8"	"229.4"	"210.7"	"258.7"	"260.7"	"447.1"	"602.1"	"755.2"	"2228.8"	"4330.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NYF8"	"Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2"	"17"	"14"	"32"	"14"	"920"	"106.1"	"9.98"	"6188.37"	"49.03"	"14"	"13"	"stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf15440"	"9774"	"ENSG00000029363"	"BCLAF1"	"A2RU75; B7ZM58; E1P586; hsa:9774; Q14673; Q86WU6; Q86WY0; Q9NYF8"	"Interactome of polycomb repressive complex 2 (PRC2)"	""	"1"	"0"	"3165.0"	"2017.6"	"2594.3"	"2237.8"	"2538.8"	"2896.6"	"6258.8"	"4731.1"	"3323.6"	"6247.7"	"7904.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q53GS9"	"U4/U6.U5 tri-snRNP-associated protein 2 OS=Homo sapiens OX=9606 GN=USP39 PE=1 SV=2"	"24"	"12"	"27"	"11"	"565"	"65.3"	"8.91"	"4997.19"	"48.77"	"12"	"12"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00443, Pf02148"	"10713"	"ENSG00000168883"	"USP39"	"A8K086; B3KM40; B4DHT4; D6W5L4; G5E9H0; hsa:10713; Q53GS9; Q6NX47; Q96RK9; Q9BV89; Q9H381; Q9P050; Q9Y310"	""	"mRNA Splicing - Major Pathway"	"1"	"1"	"446.6"	"314.8"	"389.1"	"369.8"	"427.4"	"460.3"	"2089.4"	"1957.7"	"1388.8"	"2383.4"	"3463.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3I0"	"RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1"	"30"	"13"	"24"	"13"	"505"	"55.2"	"7.23"	"2746.46"	"48.76"	"8"	"13"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01139"	"51493"	"ENSG00000100220"	"RTCB"	"B2R6A8; hsa:51493; Q6IAI0; Q9BWL4; Q9NTH1; Q9P037; Q9P0J3; Q9Y3I0"	"Unfolded protein response"	"tRNA processing in the nucleus"	"2"	"0"	"844.9"	"548.8"	"745.7"	"726.3"	"818.8"	"860.4"	"2139.7"	"1991.5"	"1613.2"	"2355.2"	"2909.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09012"	"U1 small nuclear ribonucleoprotein A OS=Homo sapiens OX=9606 GN=SNRPA PE=1 SV=3"	"36"	"8"	"32"	"6"	"282"	"31.3"	"9.83"	"5233.00"	"48.50"	"6"	"8"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6626"	"ENSG00000077312"	"SNRPA"	"hsa:6626; P09012"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"3"	"2698.6"	"1866.9"	"2270.6"	"2021.2"	"2271.0"	"2060.5"	"5062.7"	"4696.0"	"3137.7"	"4893.2"	"8008.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P68400"	"Casein kinase II subunit alpha OS=Homo sapiens OX=9606 GN=CSNK2A1 PE=1 SV=1"	"31"	"10"	"24"	"9"	"391"	"45.1"	"7.74"	"4410.57"	"47.75"	"8"	"10"	"cell-cell signaling;cell cycle OR cell proliferation;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1457"	"ENSG00000101266"	"CSNK2A1"	"B4DYS6; D3DVV8; hsa:1457; P19138; P20426; P68400; Q14013; Q5U065"	"Alzheimer's disease and miRNA effects; TNF-alpha signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Translation inhibitors in chronically activated PDGFRA cells; Measles virus infection; Pleural mesothelioma; Alzheimer's disease"	"Regulation of TP53 Activity through Phosphorylation; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Regulation of PTEN stability and activity; KEAP1-NFE2L2 pathway; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; WNT mediated activation of DVL; Signal transduction by L1; Receptor Mediated Mitophagy; Condensation of Prometaphase Chromosomes; Synthesis of PC"	"21"	"1"	"282.6"	"186.0"	"283.3"	"271.8"	"314.5"	"327.0"	"1570.6"	"1628.8"	"1328.0"	"2198.5"	"2965.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q08170"	"Serine/arginine-rich splicing factor 4 OS=Homo sapiens OX=9606 GN=SRSF4 PE=1 SV=2"	"21"	"10"	"31"	"6"	"494"	"56.6"	"11.52"	"4998.09"	"47.72"	"9"	"9"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"6429"	"ENSG00000116350"	"SRSF4"	"hsa:6429; Q08170; Q5VXP1; Q9BUA4; Q9UEB5"	"mRNA processing"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"6"	"0"	"577.3"	"381.9"	"451.7"	"499.4"	"548.9"	"542.4"	"1949.6"	"1678.9"	"1288.5"	"2596.0"	"3402.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11177"	"Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=PDHB PE=1 SV=3"	"30"	"9"	"24"	"9"	"359"	"39.2"	"6.65"	"5464.49"	"47.63"	"9"	"9"	"other metabolic processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf02779, Pf02780"	"5162"	"ENSG00000168291"	"PDHB"	"B2R7L0; B4DDD7; hsa:5162; P11177; Q6FH45; Q9BQ27; Q9UFK3"	"Metabolic reprogramming in colon cancer; Orexin receptor pathway"	"Glyoxylate metabolism and glycine degradation; Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid"	"6"	"0"	"1303.2"	"814.5"	"1361.4"	"1073.1"	"1355.1"	"1171.6"	"2347.3"	"2224.4"	"1550.0"	"2281.8"	"2885.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13247"	"Serine/arginine-rich splicing factor 6 OS=Homo sapiens OX=9606 GN=SRSF6 PE=1 SV=2"	"28"	"12"	"32"	"8"	"344"	"39.6"	"11.43"	"4464.93"	"47.12"	"8"	"11"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"6431"	"ENSG00000124193"	"SRSF6"	"B7Z6J3; E1P5W6; hsa:6431; Q13244; Q13245; Q13247; Q96J06; Q9UJB8; Q9Y3N7"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"7"	"4"	"2201.8"	"1375.9"	"1761.5"	"1659.8"	"1975.3"	"1909.8"	"5282.6"	"4947.8"	"4630.8"	"9570.9"	"12482.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04259"	"Keratin, type II cytoskeletal 6B OS=Homo sapiens OX=9606 GN=KRT6B PE=1 SV=5"	"14"	"10"	"30"	"1"	"564"	"60.0"	"8.00"	"4196.45"	"47.05"	"9"	"10"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	"bone, tooth or skin structural activity;cytoskeletal activity"	"Pf00038, Pf16208"	"3854"	"ENSG00000185479"	"KRT6B"	"hsa:3854; P04259; P48669"	""	"Formation of the cornified envelope"	"2"	"0"	"16.0"	"10.8"	"32.7"	"22.1"	"52.3"	"13.3"	"32.5"	"33.0"	"29.3"	"41.7"	"50.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HB71"	"Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2"	"40"	"10"	"25"	"10"	"228"	"26.2"	"8.25"	"4272.44"	"46.83"	"7"	"9"	"developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf04969, Pf05002, Pf09032"	"27101"	"ENSG00000116161"	"CACYBP"	"B2ZWH2; B3KSF1; hsa:27101; O60666; Q5R370; Q5R371; Q9HB71"	"Gastric cancer network 2"	""	"1"	"0"	"481.8"	"289.0"	"473.1"	"521.3"	"531.2"	"667.6"	"3034.8"	"3080.3"	"2606.6"	"5569.5"	"12517.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46109"	"Crk-like protein OS=Homo sapiens OX=9606 GN=CRKL PE=1 SV=1"	"41"	"9"	"25"	"9"	"303"	"33.8"	"6.74"	"4026.63"	"46.55"	"8"	"9"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00017, Pf00018, Pf07653"	"1399"	"ENSG00000099942"	"CRKL"	"A8KA44; D3DX35; hsa:1399; P46109"	"Androgen receptor network in prostate cancer; B cell receptor signaling pathway; IL-3 signaling pathway; Kit receptor signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; MAPK signaling pathway; Chemokine signaling pathway; EGF/EGFR signaling pathway; 22q11.2 copy number variation syndrome; IL-2 signaling pathway; A network map of Macrophage-stimulating protein (MSP) signaling; Interferon type I signaling pathways; ErbB signaling pathway; T-cell receptor signaling pathway"	"Regulation of signaling by CBL; Downstream signal transduction; Erythropoietin activates RAS; Frs2-mediated activation; MET activates RAP1 and RAC1; MET receptor recycling"	"21"	"0"	"663.5"	"511.9"	"743.6"	"660.4"	"697.7"	"700.9"	"1001.1"	"917.6"	"687.6"	"1115.2"	"1453.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5JSL3"	"Dedicator of cytokinesis protein 11 OS=Homo sapiens OX=9606 GN=DOCK11 PE=1 SV=2"	"8"	"13"	"28"	"13"	"2073"	"237.5"	"7.74"	"5484.53"	"46.49"	"12"	"11"	"signal transduction;other biological processes"	"cytosol"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf06920, Pf11878, Pf14429, Pf20421, Pf20422"	"139818"	"ENSG00000147251"	"DOCK11"	"A6NMF0; hsa:139818; Q5JSL3; Q66M66; Q6ZUJ5; Q86VU8; Q96MN3"	""	"CDC42 GTPase cycle; RAC1 GTPase cycle; Factors involved in megakaryocyte development and platelet production"	"3"	"0"	"370.3"	"226.7"	"298.4"	"301.5"	"312.0"	"371.3"	"932.0"	"971.2"	"1607.4"	"3552.6"	"3605.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43852"	"Calumenin OS=Homo sapiens OX=9606 GN=CALU PE=1 SV=2"	"39"	"12"	"25"	"12"	"315"	"37.1"	"4.64"	"4413.63"	"46.43"	"11"	"11"	""	"non-structural extracellular;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf13833"	"813"	"ENSG00000128595"	"CALU"	"B3KPG9; D6QS48; D6QS49; D6QS50; D6QS51; D6QS52; D6QS53; D6QS54; D6QS55; D6QS56; D6QS57; D6QS58; D6QS59; F5H1Q9; F5H879; hsa:813; O43852; O60456; Q6FHB9; Q96RL3; Q9NR43"	"NOTCH1 regulation of endothelial cell calcification; VEGFA-VEGFR2 signaling"	"Platelet degranulation ; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation"	"5"	"0"	"1199.9"	"574.8"	"864.5"	"1054.5"	"960.9"	"1120.3"	"2604.9"	"2602.9"	"1815.0"	"2736.0"	"3743.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15365"	"Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2"	"37"	"11"	"26"	"5"	"356"	"37.5"	"7.09"	"5279.26"	"45.96"	"10"	"10"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013"	"5093"	"ENSG00000169564"	"PCBP1"	"hsa:5093; Q13157; Q14975; Q15365"	"Ferroptosis"	"Processing of Capped Intron-Containing Pre-mRNA; mRNA Splicing - Major Pathway"	"3"	"9"	"2313.4"	"1145.4"	"1589.7"	"1799.0"	"1835.1"	"2229.4"	"4460.9"	"4358.5"	"2964.3"	"4110.0"	"4806.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96AE4"	"Far upstream element-binding protein 1 OS=Homo sapiens OX=9606 GN=FUBP1 PE=1 SV=3"	"22"	"15"	"32"	"10"	"644"	"67.5"	"7.61"	"5450.23"	"45.76"	"15"	"15"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00013, Pf09005"	"8880"	"ENSG00000162613"	"FUBP1"	"hsa:8880; Q12828; Q96AE4"	""	""	"0"	"5"	"1501.3"	"852.3"	"1136.9"	"1073.6"	"1126.3"	"1401.1"	"2746.4"	"2487.7"	"1818.0"	"2823.2"	"3281.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P15880"	"40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2"	"32"	"10"	"32"	"10"	"293"	"31.3"	"10.24"	"5515.93"	"45.49"	"9"	"10"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00333, Pf03719"	"6187"	"ENSG00000140988"	"RPS2"	"B2R5G0; D3DU82; hsa:6187; P15880; Q3MIB1"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; RMTs methylate histone arginines; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Protein methylation; Peptide chain elongation; rRNA modification in the nucleus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"22"	"0"	"1898.7"	"1199.6"	"1643.9"	"1301.6"	"1337.2"	"1608.0"	"4636.1"	"4249.0"	"3085.8"	"4390.1"	"6143.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92945"	"Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4"	"22"	"13"	"27"	"10"	"711"	"73.1"	"7.30"	"4393.27"	"45.40"	"12"	"12"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf09005"	"8570"	"ENSG00000088247"	"KHSRP"	"hsa:8570; O00301; Q59EZ9; Q5U4P6; Q92945; Q9UNT5; Q9UQH5"	"Pre-implantation embryo"	"ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA"	"3"	"0"	"1056.8"	"690.7"	"824.9"	"708.3"	"823.7"	"1049.3"	"1639.5"	"1353.0"	"962.0"	"1724.2"	"2030.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49736"	"DNA replication licensing factor MCM2 OS=Homo sapiens OX=9606 GN=MCM2 PE=1 SV=4"	"16"	"13"	"26"	"13"	"904"	"101.8"	"5.52"	"4583.27"	"45.35"	"11"	"11"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf12619, Pf14551, Pf17207, Pf17855"	"4171"	"ENSG00000073111"	"MCM2"	"hsa:4171; P49736; Q14577; Q15023; Q8N2V1; Q969W7; Q96AE1; Q9BRM7"	"Cell cycle; Ciliary landscape; G1 to S cell cycle control; DNA replication; 1p36 copy number variation syndrome"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"11"	"0"	"1128.6"	"702.0"	"1048.7"	"842.1"	"987.4"	"1069.7"	"1684.9"	"1479.7"	"1044.7"	"1666.3"	"2199.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95831"	"Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1"	"20"	"10"	"24"	"10"	"613"	"66.9"	"8.95"	"4004.34"	"45.24"	"8"	"10"	"cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00070, Pf14721"	"9131"	"ENSG00000156709"	"AIFM1"	"A4QPB4; B1ALN1; B2RB08; D3DTE9; E9PRR0; hsa:9131; O95831; Q1L6K4; Q1L6K6; Q2QKE4; Q5JUZ7; Q6I9X6; Q9Y3I3; Q9Y3I4"	"Apoptosis modulation and signaling; Nanomaterial induced apoptosis; Apoptosis modulation by HSP70"	""	"3"	"0"	"978.2"	"599.6"	"865.1"	"930.3"	"846.5"	"1139.0"	"1739.8"	"1685.1"	"1318.3"	"2000.2"	"3056.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q10570"	"Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2"	"13"	"15"	"27"	"15"	"1443"	"160.8"	"6.40"	"5136.90"	"45.16"	"14"	"13"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03178, Pf10433"	"29894"	"ENSG00000071894; ENSG00000285049"	"CPSF1"	"hsa:29894; Q10570; Q96AF0"	"mRNA processing"	"Transport of Mature mRNA Derived from an Intronless Transcript; tRNA processing in the nucleus; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"7"	"0"	"904.8"	"610.4"	"1036.7"	"949.1"	"1012.9"	"1086.3"	"1833.2"	"1761.4"	"1253.4"	"1825.0"	"2076.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31930"	"Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3"	"34"	"12"	"21"	"12"	"480"	"52.6"	"6.37"	"3307.90"	"45.03"	"8"	"11"	"other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00675, Pf05193"	"7384"	"ENSG00000010256"	"UQCRC1"	"B2R7R8; hsa:7384; P31930; Q96DD2"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex III assembly"	"Respiratory electron transport"	"4"	"0"	"1260.9"	"671.6"	"943.0"	"1142.1"	"1020.5"	"1222.1"	"1497.9"	"1341.0"	"984.0"	"1531.9"	"1946.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42285"	"Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3"	"16"	"15"	"27"	"15"	"1042"	"117.7"	"6.52"	"3973.61"	"44.73"	"11"	"14"	"RNA metabolism OR transcription;other metabolic processes;stress response"	"nucleus"	"other molecular function"	"Pf00270, Pf00271, Pf08148, Pf13234"	"23517"	"ENSG00000039123"	"MTREX"	"hsa:23517; P42285; Q2M386; Q6MZZ8; Q6P170; Q8N5R0; Q8TAG2"	""	"mRNA Splicing - Major Pathway; Major pathway of rRNA processing in the nucleolus and cytosol"	"2"	"0"	"677.9"	"410.7"	"608.9"	"597.0"	"640.2"	"751.6"	"2164.2"	"2093.0"	"1511.5"	"2668.8"	"4246.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22061"	"Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4"	"38"	"9"	"29"	"9"	"227"	"24.6"	"7.21"	"6187.57"	"44.73"	"9"	"8"	"protein metabolism;other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf01135"	"5110"	"ENSG00000120265"	"PCMT1"	"A8K109; hsa:5110; J3KP72; P22061; Q14661; Q16556; Q5VYC1; Q5VYC2; Q93061; Q96II9; Q99625; Q9BQV7; Q9BQV8; Q9NP03"	"Primary ovarian insufficiency"	"Protein repair"	"2"	"0"	"2678.0"	"1028.2"	"1628.0"	"2572.8"	"1539.6"	"2391.2"	"3202.0"	"3147.0"	"2441.7"	"3447.6"	"4948.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62304"	"Small nuclear ribonucleoprotein E OS=Homo sapiens OX=9606 GN=SNRPE PE=1 SV=1"	"72"	"6"	"23"	"6"	"92"	"10.8"	"9.44"	"3585.63"	"44.67"	"3"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	"6635"	"ENSG00000182004"	"SNRPE"	"B2R5B9; hsa:6635; P08578; P62304; Q15498; Q5BKT2"	"mRNA processing"	"mRNA Splicing - Major Pathway; SARS-CoV-2 modulates host translation machinery; snRNP Assembly; RNA Polymerase II Transcription Termination; mRNA Splicing - Minor Pathway; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"8"	"0"	"319.7"	"233.5"	"356.7"	"278.5"	"306.5"	"256.8"	"539.0"	"578.6"	"478.2"	"746.1"	"951.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P33992"	"DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5"	"20"	"11"	"24"	"11"	"734"	"82.2"	"8.37"	"4021.37"	"44.58"	"8"	"11"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855"	"4174"	"ENSG00000100297"	"MCM5"	"hsa:4174; O60785; P33992; Q14578; Q9BTJ4; Q9BWL8"	"Cell cycle; Ciliary landscape; G1 to S cell cycle control; DNA replication"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"10"	"0"	"478.1"	"384.3"	"491.8"	"413.9"	"491.3"	"586.6"	"1412.2"	"1350.9"	"1021.5"	"1416.1"	"1710.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P38919"	"Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4"	"27"	"13"	"28"	"12"	"411"	"46.8"	"6.73"	"5471.22"	"44.50"	"12"	"10"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"9775"	"ENSG00000141543"	"EIF4A3"	"hsa:9775; P38919; Q15033; Q6IBQ2; Q96A18"	"TAR syndrome"	"mRNA Splicing - Major Pathway; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Deadenylation of mRNA; ISG15 antiviral mechanism; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"9"	"1"	"1649.2"	"970.5"	"1601.6"	"1201.5"	"1469.9"	"1598.9"	"2660.3"	"2533.5"	"2342.1"	"3746.6"	"4942.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11908"	"Ribose-phosphate pyrophosphokinase 2 OS=Homo sapiens OX=9606 GN=PRPS2 PE=1 SV=2"	"31"	"9"	"30"	"3"	"318"	"34.7"	"6.61"	"5942.95"	"44.46"	"9"	"9"	"other metabolic processes;other biological processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf13793, Pf14572"	"5634"	"ENSG00000101911"	"PRPS2"	"hsa:5634; P11908; Q0VDH9; Q0VDI0; Q15245; Q2TAK7"	""	"5-Phosphoribose 1-diphosphate biosynthesis"	"1"	"0"	"397.6"	"186.7"	"253.2"	"390.2"	"305.4"	"405.8"	"523.8"	"539.0"	"408.9"	"562.2"	"644.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60842"	"Eukaryotic initiation factor 4A-I OS=Homo sapiens OX=9606 GN=EIF4A1 PE=1 SV=1"	"26"	"11"	"30"	"4"	"406"	"46.1"	"5.48"	"6548.10"	"44.30"	"11"	"8"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"1973"	"ENSG00000161960"	"EIF4A1"	"B2R6L8; D3DTP9; hsa:1973; J3QLC4; P04765; P60842; Q5U018; Q61516"	"Translation factors; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Interferon type I signaling pathways"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Translation initiation complex formation; Ribosomal scanning and start codon recognition; Deadenylation of mRNA; ISG15 antiviral mechanism"	"11"	"6"	"1734.5"	"1000.6"	"1656.1"	"1334.0"	"1475.9"	"1503.3"	"2167.5"	"2135.5"	"1745.7"	"2419.6"	"3240.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q04917"	"14-3-3 protein eta OS=Homo sapiens OX=9606 GN=YWHAH PE=1 SV=4"	"35"	"10"	"31"	"7"	"246"	"28.2"	"4.84"	"5524.53"	"44.29"	"9"	"8"	"other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00244"	"7533"	"ENSG00000128245"	"YWHAH"	"hsa:7533; Q04917"	"Cell cycle; Myometrial relaxation and contraction pathways; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; TP53 Regulates Metabolic Genes; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Activation of BAD and translocation to mitochondria"	"11"	"0"	"671.1"	"375.2"	"644.4"	"597.4"	"627.8"	"668.8"	"1163.0"	"1170.8"	"875.5"	"1310.7"	"1760.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75937"	"DnaJ homolog subfamily C member 8 OS=Homo sapiens OX=9606 GN=DNAJC8 PE=1 SV=2"	"38"	"10"	"21"	"10"	"253"	"29.8"	"9.06"	"3327.66"	"44.10"	"8"	"10"	""	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00226"	"22826"	"ENSG00000126698; ENSG00000285317"	"DNAJC8"	"B4DUU4; D3DPM0; hsa:22826; O75937; Q6IBA4; Q8N4Z5; Q9P051; Q9P067"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"580.7"	"302.9"	"539.6"	"541.9"	"642.3"	"620.8"	"2677.3"	"2575.2"	"2005.4"	"3911.7"	"7881.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UHX1"	"Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1"	"18"	"9"	"22"	"9"	"559"	"59.8"	"5.29"	"3368.35"	"43.98"	"8"	"9"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"22827"	"ENSG00000179950; ENSG00000274081"	"PUF60"	"A8K8K8; hsa:22827; Q969E7; Q96D94; Q96H63; Q99628; Q9NZA0; Q9UHX1; Q9UJY7"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"1414.5"	"893.4"	"1219.4"	"976.4"	"1425.8"	"1216.9"	"1862.6"	"1735.4"	"1343.2"	"2212.7"	"3294.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P27816"	"Microtubule-associated protein 4 OS=Homo sapiens OX=9606 GN=MAP4 PE=1 SV=3"	"15"	"14"	"29"	"14"	"1152"	"120.9"	"5.43"	"6174.13"	"43.77"	"14"	"12"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00418"	"4134"	"ENSG00000047849"	"MAP4"	"hsa:4134; P27816; Q13082; Q59FT2; Q68D74; Q6ZUW9; Q86V26; Q96A76; Q96NS9"	"Splicing factor NOVA regulated synaptic proteins; 2q37 copy number variation syndrome"	""	"2"	"0"	"973.8"	"591.4"	"771.7"	"738.5"	"840.4"	"843.2"	"2602.4"	"2362.8"	"1700.1"	"2826.1"	"3784.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99832"	"T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2"	"24"	"11"	"25"	"11"	"543"	"59.3"	"7.65"	"3710.52"	"43.49"	"8"	"11"	"protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00118"	"10574"	"ENSG00000135624"	"CCT7"	"A8K7E6; A8MWI8; B7WNW9; B7Z4T9; B7Z4Z7; hsa:10574; O14871; Q6FI26; Q99832"	"VEGFA-VEGFR2 signaling; 16p11.2 proximal deletion syndrome"	"Formation of tubulin folding intermediates by CCT/TriC; RHOBTB1 GTPase cycle; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; RHOBTB2 GTPase cycle; Folding of actin by CCT/TriC"	"9"	"0"	"1279.7"	"849.8"	"1431.8"	"1145.2"	"1289.5"	"1301.8"	"1852.0"	"1528.9"	"1125.0"	"1942.3"	"2970.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00148"	"ATP-dependent RNA helicase DDX39A OS=Homo sapiens OX=9606 GN=DDX39A PE=1 SV=2"	"21"	"9"	"32"	"1"	"427"	"49.1"	"5.68"	"5657.83"	"43.38"	"9"	"9"	"RNA metabolism OR transcription;other metabolic processes;transport"	"nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271"	"10212"	"ENSG00000123136"	"DDX39A"	"B1Q2N1; hsa:10212; O00148; Q8N5M0; Q9BVP6; Q9H5W0"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NBS9"	"Thioredoxin domain-containing protein 5 OS=Homo sapiens OX=9606 GN=TXNDC5 PE=1 SV=2"	"28"	"12"	"27"	"11"	"432"	"47.6"	"5.97"	"3623.67"	"43.35"	"9"	"11"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;ER/Golgi;other cytoplasmic organelle"	"other molecular function"	"Pf00085"	"81567"	"ENSG00000239264"	"TXNDC5"	"B2RDM2; hsa:81567; Q5TCQ0; Q8NBS9; Q8ND33; Q8TCT2; Q9BVH9"	"VEGFA-VEGFR2 signaling"	"Neutrophil degranulation; Lysosome Vesicle Biogenesis; Golgi Associated Vesicle Biogenesis"	"4"	"1"	"1647.3"	"1084.3"	"1596.5"	"1449.3"	"1457.2"	"1643.8"	"2574.7"	"2505.8"	"1797.0"	"2309.4"	"2714.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62753"	"40S ribosomal protein S6 OS=Homo sapiens OX=9606 GN=RPS6 PE=1 SV=1"	"29"	"11"	"30"	"11"	"249"	"28.7"	"10.84"	"5491.65"	"43.33"	"11"	"9"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01092"	"6194"	"ENSG00000137154"	"RPS6"	"hsa:6194; P08227; P10660; P62753; Q4VBY7; Q8N6Z7"	"IL-5 signaling pathway; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Follicle stimulating hormone (FSH) signaling pathway; Prolactin signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; Interleukin-11 signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Kit receptor signaling pathway; MECP2 and associated Rett syndrome; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Thermogenesis; Translation inhibitors in chronically activated PDGFRA cells; Gastrin signaling pathway; Head and neck squamous cell carcinoma; Thyroid hormones production and peripheral downstream signaling effects; Cytoplasmic ribosomal proteins; EGFR tyrosine kinase inhibitor resistance; IL-2 signaling pathway; Pleural mesothelioma; 2q37 copy number variation syndrome; A network map of Macrophage-stimulating protein (MSP) signaling; Interferon type I signaling pathways"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery; mTORC1-mediated signalling; rRNA modification in the nucleus and cytosol; Nuclear events stimulated by ALK signaling in cancer"	"47"	"0"	"1825.7"	"1095.2"	"1498.2"	"1260.9"	"1528.4"	"1329.9"	"4558.5"	"4203.5"	"3063.9"	"4186.3"	"4918.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15366"	"Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1"	"30"	"10"	"27"	"4"	"365"	"38.6"	"6.79"	"5810.25"	"43.16"	"9"	"9"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013"	"5094"	"ENSG00000197111"	"PCBP2"	"A8K7X6; B4DXP5; F8VYL7; G3V0E8; hsa:5094; I6L8F9; Q15366; Q32Q82; Q59HD4; Q68Y55; Q6IPF4; Q6PKG5"	"mRNA processing; Ferroptosis; Modulators of TCR signaling and T cell activation"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA; Negative regulators of DDX58/IFIH1 signaling; SARS-CoV-1 activates/modulates innate immune responses"	"7"	"0"	"516.3"	"328.1"	"403.0"	"511.2"	"447.4"	"615.9"	"1331.3"	"1371.8"	"1006.2"	"1281.7"	"1338.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TCS8"	"Polyribonucleotide nucleotidyltransferase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PNPT1 PE=1 SV=2"	"20"	"12"	"23"	"12"	"783"	"85.9"	"7.77"	"4780.53"	"42.90"	"11"	"12"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;mitochondrion;ER/Golgi;translational apparatus;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf01138, Pf03725, Pf03726"	"87178"	"ENSG00000138035"	"PNPT1"	"hsa:87178; Q53SU0; Q68CN1; Q7Z7D1; Q8IWX1; Q8TCS8; Q96T05; Q9BRU3; Q9BVX0"	"Pyrimidine metabolism; miRNA degrading enzymes"	""	"2"	"0"	"386.6"	"247.7"	"364.4"	"334.0"	"339.4"	"398.2"	"974.4"	"1021.9"	"810.2"	"1235.2"	"1660.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12955"	"Ankyrin-3 OS=Homo sapiens OX=9606 GN=ANK3 PE=1 SV=3"	"4"	"15"	"25"	"12"	"4377"	"480.1"	"6.49"	"3824.54"	"42.81"	"11"	"14"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00531, Pf00791, Pf12796, Pf17809"	"288"	"ENSG00000151150"	"ANK3"	"B1AQT2; B4DIL1; E9PE32; hsa:288; Q12955; Q13484; Q5CZH9; Q5VXD5; Q7Z3G4; Q9H0P5"	"Splicing factor NOVA regulated synaptic proteins"	"COPI-mediated anterograde transport; Interaction between L1 and Ankyrins"	"3"	"2"	"534.0"	"317.8"	"479.5"	"566.8"	"538.0"	"627.9"	"1338.8"	"1283.4"	"972.2"	"1458.9"	"1789.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25705"	"ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1"	"23"	"11"	"27"	"11"	"553"	"59.7"	"9.13"	"4900.03"	"42.74"	"10"	"11"	"other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;transporter activity;other molecular function"	"Pf00006, Pf00306, Pf02874"	"498"	"ENSG00000152234"	"ATP5F1A"	"A8K092; B4DY56; hsa:498; K7ENP3; P25705; Q53XX6; Q8IXV2; Q96FB4; Q96HW2; Q96IR6; Q9BTV8"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"Mitochondrial protein import; Cristae formation; Formation of ATP by chemiosmotic coupling"	"6"	"0"	"1345.0"	"838.8"	"1015.0"	"1026.8"	"1097.4"	"1279.0"	"2034.4"	"2120.2"	"1488.9"	"2230.5"	"2678.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62701"	"40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2"	"46"	"13"	"34"	"13"	"263"	"29.6"	"10.15"	"5445.99"	"42.72"	"13"	"12"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00467, Pf00900, Pf01479, Pf08071, Pf16121"	"6191"	"ENSG00000198034"	"RPS4X"	"hsa:6191; P12631; P12750; P27576; P55831; P62701; Q14727; Q6IPY4"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"2441.9"	"1637.9"	"2245.5"	"1874.2"	"2044.6"	"1977.9"	"5237.7"	"4811.5"	"3340.1"	"4846.9"	"6760.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P40227"	"T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3"	"27"	"12"	"24"	"12"	"531"	"58.0"	"6.68"	"3610.38"	"42.71"	"8"	"11"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00118"	"908"	"ENSG00000146731"	"CCT6A"	"A6NCD2; hsa:908; P40227; Q3KP28; Q75LP4; Q96S46"	"16p11.2 proximal deletion syndrome"	"Formation of tubulin folding intermediates by CCT/TriC; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; RHOBTB2 GTPase cycle; Folding of actin by CCT/TriC"	"7"	"0"	"1442.9"	"1023.9"	"1453.5"	"1106.2"	"1356.3"	"1407.5"	"1710.8"	"1626.0"	"1247.7"	"1873.0"	"2699.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BUQ8"	"Probable ATP-dependent RNA helicase DDX23 OS=Homo sapiens OX=9606 GN=DDX23 PE=1 SV=3"	"14"	"12"	"28"	"12"	"820"	"95.5"	"9.55"	"5412.64"	"42.50"	"12"	"10"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271"	"9416"	"ENSG00000174243"	"DDX23"	"B2R600; B4DH15; hsa:9416; O43188; Q9BUQ8"	""	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"2"	"0"	"911.0"	"557.8"	"765.8"	"644.8"	"807.2"	"705.1"	"2162.4"	"2020.9"	"1532.6"	"2575.9"	"3318.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75390"	"Citrate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=CS PE=1 SV=2"	"19"	"9"	"28"	"9"	"466"	"51.7"	"8.32"	"5111.14"	"42.50"	"9"	"9"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00285"	"1431"	"ENSG00000062485"	"CS"	"hsa:1431; O75390; Q71UT9; Q7KZH0; Q96FZ8; Q9BWN8"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Fluoroacetic acid toxicity; TCA cycle (aka Krebs or citric acid cycle)"	"Citric acid cycle (TCA cycle); Mitochondrial protein import"	"6"	"0"	"1542.8"	"1086.4"	"1650.2"	"1449.6"	"1717.2"	"1519.7"	"2130.8"	"2029.5"	"1617.6"	"2118.2"	"2715.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08708"	"40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2"	"57"	"7"	"13"	"7"	"135"	"15.5"	"9.85"	"1459.89"	"42.45"	"4"	"7"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00833"	"6218"	"ENSG00000182774; ENSG00000278229"	"RPS17"	"B2R4U4; hsa:6218; P08708; P0CW22"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"458.1"	"321.8"	"424.9"	"393.7"	"422.8"	"451.9"	"1316.2"	"1275.4"	"931.3"	"1382.3"	"1575.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WXF1"	"Paraspeckle component 1 OS=Homo sapiens OX=9606 GN=PSPC1 PE=1 SV=1"	"20"	"10"	"21"	"10"	"523"	"58.7"	"6.67"	"3474.69"	"42.25"	"9"	"10"	"stress response;other biological processes"	"nucleus;other cell component"	""	"Pf00076, Pf08075"	"55269"	"ENSG00000121390"	"PSPC1"	"hsa:55269; Q5JTQ3; Q8NCZ9; Q8WXE8; Q8WXF1; Q9NV36"	""	""	"0"	"0"	"798.1"	"415.8"	"680.3"	"679.2"	"707.2"	"710.2"	"2440.2"	"2416.1"	"1683.3"	"2597.8"	"3632.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NZT1"	"Calmodulin-like protein 5 OS=Homo sapiens OX=9606 GN=CALML5 PE=1 SV=2"	"53"	"5"	"21"	"5"	"146"	"15.9"	"4.44"	"4525.91"	"42.12"	"4"	"5"	"signal transduction;other biological processes"	"non-structural extracellular;other cell component"	"enzyme regulator activity;other molecular function"	"Pf13499"	"51806"	"ENSG00000178372"	"CALML5"	"hsa:51806; Q5SQI3; Q8IXU8; Q9NZT1"	"Alzheimer's disease and miRNA effects; Ras signaling; Melanoma; Alzheimer's disease"	"Neutrophil degranulation"	"5"	"0"	"155.9"	"104.4"	"357.4"	"162.4"	"248.4"	"175.9"	"876.7"	"864.8"	"762.5"	"1089.7"	"1151.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50995"	"Annexin A11 OS=Homo sapiens OX=9606 GN=ANXA11 PE=1 SV=1"	"25"	"11"	"26"	"11"	"505"	"54.4"	"7.65"	"4505.34"	"42.11"	"11"	"11"	"cell cycle OR cell proliferation;transport;other biological processes"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00191"	"311"	"ENSG00000122359"	"ANXA11"	"B4DVE7; hsa:311; P50995"	""	""	"0"	"0"	"1360.2"	"581.8"	"847.7"	"1101.7"	"906.0"	"1125.8"	"2328.9"	"2144.5"	"1614.0"	"2577.1"	"3837.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52292"	"Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1"	"25"	"10"	"20"	"10"	"529"	"57.8"	"5.40"	"3653.39"	"42.03"	"9"	"8"	"DNA metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf01749, Pf16186"	"3838"	"ENSG00000182481"	"KPNA2"	"B9EJD6; hsa:3838; P52292; Q53YE3; Q6NVW7; Q9BRU5"	""	"ISG15 antiviral mechanism; NS1 Mediated Effects on Host Pathways; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Estrogen-dependent gene expression; SARS-CoV-1 activates/modulates innate immune responses; Sensing of DNA Double Strand Breaks; CaMK IV-mediated phosphorylation of CREB; CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde"	"8"	"0"	"1009.4"	"570.6"	"935.4"	"1024.9"	"952.6"	"1099.0"	"2472.0"	"2390.8"	"1700.9"	"2323.5"	"2871.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15283"	"Ras GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=RASA2 PE=1 SV=3"	"18"	"13"	"27"	"13"	"850"	"96.6"	"7.20"	"4497.97"	"41.88"	"11"	"12"	"signal transduction;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00168, Pf00169, Pf00616, Pf00779"	"5922"	"ENSG00000155903"	"RASA2"	"A8K7K1; G3V0F9; hsa:5922; O00695; Q15283; Q15284; Q92594; Q99577; Q9UEQ2"	"MAPK signaling pathway; Ebola virus infection in host; Ras signaling; Modulators of TCR signaling and T cell activation"	"Regulation of RAS by GAPs"	"5"	"0"	"286.1"	"223.9"	"319.7"	"324.4"	"301.2"	"444.7"	"1576.6"	"2707.2"	"2364.2"	"3463.3"	"4014.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H9Y6"	"DNA-directed RNA polymerase I subunit RPA2 OS=Homo sapiens OX=9606 GN=POLR1B PE=1 SV=2"	"14"	"14"	"27"	"14"	"1135"	"128.1"	"7.83"	"4918.01"	"41.87"	"14"	"13"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00562, Pf04560, Pf04561, Pf04563, Pf04565, Pf06883"	"84172"	"ENSG00000125630"	"POLR1B"	"B7Z6Y7; B7Z823; F5GZX4; F8W898; hsa:84172; Q2TAM4; Q585T5; Q6ZRR2; Q9H9D3; Q9H9Y6"	"Pyrimidine metabolism; Eukaryotic transcription initiation; 2q13 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"8"	"0"	"322.9"	"217.4"	"302.8"	"333.2"	"383.1"	"406.6"	"743.8"	"1505.1"	"1788.9"	"3259.3"	"4112.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBU9"	"Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1"	"22"	"10"	"21"	"10"	"619"	"70.1"	"8.51"	"4099.39"	"41.60"	"9"	"10"	"other metabolic processes;transport"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf02136, Pf03943, Pf09162"	"10482"	"ENSG00000162231"	"NXF1"	"B4E269; hsa:10482; Q99799; Q9UBU9; Q9UQL2"	"mRNA processing"	"Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"5"	"0"	"370.9"	"238.7"	"311.0"	"306.0"	"332.4"	"343.0"	"1310.0"	"1243.3"	"928.5"	"1500.7"	"1687.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96T37"	"RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2"	"12"	"10"	"23"	"9"	"977"	"107.1"	"10.08"	"4003.91"	"41.35"	"9"	"10"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other membranes;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf07744"	"64783"	"ENSG00000162775"	"RBM15"	"A1A693; hsa:64783; Q3ZB86; Q4V760; Q5D058; Q5T613; Q86VW9; Q96PE4; Q96SC5; Q96SC6; Q96SC9; Q96SD0; Q96T37; Q96T38; Q9BRA5; Q9H6R8; Q9H9Y0"	""	""	"0"	"1"	"331.9"	"226.9"	"300.8"	"295.8"	"327.1"	"355.3"	"1253.2"	"1636.9"	"1456.3"	"3281.2"	"4786.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49368"	"T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4"	"33"	"15"	"26"	"15"	"545"	"60.5"	"6.49"	"5060.81"	"41.32"	"13"	"12"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00118"	"7203"	"ENSG00000163468"	"CCT3"	"A6NE14; hsa:7203; P49368; Q5SZY1; Q9BR64"	"16p11.2 proximal deletion syndrome"	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Association of TriC/CCT with target proteins during biosynthesis; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"7"	"0"	"1296.8"	"969.8"	"1344.8"	"1131.6"	"1210.5"	"1334.1"	"1746.2"	"1607.2"	"1245.5"	"1921.8"	"2539.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NR30"	"Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5"	"15"	"10"	"24"	"8"	"783"	"87.3"	"9.28"	"4085.76"	"41.05"	"10"	"10"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf08152"	"9188"	"ENSG00000165732"	"DDX21"	"B2RDL0; hsa:9188; Q13436; Q5VX41; Q68D35; Q9NR30"	"10q11.21q11.23 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; Major pathway of rRNA processing in the nucleolus and cytosol"	"3"	"2"	"513.3"	"332.4"	"501.3"	"415.0"	"517.8"	"471.5"	"1232.9"	"1061.4"	"714.0"	"1346.6"	"2003.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61221"	"ATP-binding cassette sub-family E member 1 OS=Homo sapiens OX=9606 GN=ABCE1 PE=1 SV=1"	"24"	"10"	"19"	"10"	"599"	"67.3"	"8.34"	"2952.10"	"40.89"	"8"	"10"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;mitochondrion;translational apparatus;other cell component"	"enzyme regulator activity;translation activity;other molecular function"	"Pf00005, Pf00037, Pf04068"	"6059"	"ENSG00000164163"	"ABCE1"	"hsa:6059; O88793; P61221; Q13181; Q13864; Q6NR76; Q96AL0; Q96B10; Q99K66"	""	"OAS antiviral response; Interferon alpha/beta signaling"	"2"	"0"	"372.7"	"254.9"	"409.1"	"392.6"	"459.5"	"444.1"	"1803.1"	"1794.9"	"1483.7"	"2516.5"	"3412.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A0FGR8"	"Extended synaptotagmin-2 OS=Homo sapiens OX=9606 GN=ESYT2 PE=1 SV=1"	"10"	"8"	"19"	"8"	"921"	"102.3"	"9.26"	"3047.91"	"40.87"	"5"	"8"	"cell organization and biogenesis;transport"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00168, Pf17047"	"57488"	"ENSG00000117868"	"ESYT2"	"A0FGR8; A4D229; hsa:57488; Q69YJ2; Q6UKI4; Q6ZTU0; Q6ZVU1; Q9BQS0; Q9NW47; Q9ULJ2"	""	"Glycosphingolipid metabolism"	"1"	"0"	"344.7"	"201.9"	"309.6"	"290.5"	"311.1"	"373.8"	"749.0"	"1220.3"	"1482.9"	"2971.7"	"4143.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16531"	"DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1"	"11"	"13"	"24"	"13"	"1140"	"126.9"	"5.26"	"3468.38"	"40.64"	"11"	"13"	"cell-cell signaling;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03178, Pf10433"	"1642"	"ENSG00000167986"	"DDB1"	"A6NG77; B2R648; B4DG00; hsa:1642; O15176; Q13289; Q16531; Q58F96"	"Hippo-Merlin signaling dysregulation; Hepatitis B infection; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"Neddylation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; DNA Damage Recognition in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; Dual Incision in GG-NER"	"14"	"0"	"897.7"	"632.8"	"937.1"	"783.5"	"977.0"	"900.7"	"1409.0"	"1309.2"	"1006.6"	"1570.3"	"2433.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55209"	"Nucleosome assembly protein 1-like 1 OS=Homo sapiens OX=9606 GN=NAP1L1 PE=1 SV=1"	"20"	"6"	"20"	"5"	"391"	"45.3"	"4.46"	"3924.58"	"40.44"	"6"	"6"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00956"	"4673"	"ENSG00000187109"	"NAP1L1"	"B3KNT8; B3KV44; hsa:4673; P55209"	"VEGFA-VEGFR2 signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies"	""	"2"	"0"	"224.2"	"156.9"	"269.2"	"218.3"	"361.8"	"248.3"	"582.9"	"506.0"	"337.8"	"626.2"	"784.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08579"	"U2 small nuclear ribonucleoprotein B'' OS=Homo sapiens OX=9606 GN=SNRPB2 PE=1 SV=1"	"32"	"7"	"27"	"5"	"225"	"25.5"	"9.72"	"3844.51"	"40.40"	"6"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6629"	"ENSG00000125870"	"SNRPB2"	"B2R7J3; D3DW21; hsa:6629; P08579; Q9UJD4"	"mRNA processing; Ciliary landscape"	"mRNA Splicing - Major Pathway"	"3"	"0"	"1832.8"	"1017.2"	"1395.5"	"1189.3"	"1281.2"	"1087.1"	"2965.8"	"2525.6"	"1861.5"	"2591.1"	"3888.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P15924"	"Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3"	"7"	"16"	"25"	"16"	"2871"	"331.6"	"6.81"	"4083.66"	"40.28"	"13"	"12"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00681, Pf17902, Pf18373"	"1832"	"ENSG00000096696"	"DSP"	"B2RTT2; D7RX09; hsa:1832; O75993; P15924; Q14189; Q9UHN4"	"Arrhythmogenic right ventricular cardiomyopathy; Lung fibrosis; Epithelial to mesenchymal transition in colorectal cancer"	"Neutrophil degranulation; Formation of the cornified envelope; RND3 GTPase cycle; RND1 GTPase cycle; Apoptotic cleavage of cell adhesion  proteins"	"9"	"0"	"618.1"	"401.1"	"693.9"	"505.5"	"600.3"	"640.7"	"784.7"	"754.6"	"606.5"	"892.7"	"1319.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P32119"	"Peroxiredoxin-2 OS=Homo sapiens OX=9606 GN=PRDX2 PE=1 SV=5"	"38"	"10"	"25"	"9"	"198"	"21.9"	"5.97"	"5614.30"	"40.13"	"10"	"9"	"cell cycle OR cell proliferation;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00578, Pf10417"	"7001"	"ENSG00000167815"	"PRDX2"	"A8K0C0; hsa:7001; P31945; P32118; P32119; P35701; Q6FHG4; Q92763; Q9UC23"	"Selenium micronutrient network; VEGFA-VEGFR2 signaling"	"TP53 Regulates Metabolic Genes; Detoxification of Reactive Oxygen Species; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"	"5"	"0"	"1414.9"	"680.2"	"1069.4"	"1027.6"	"870.2"	"1115.7"	"1534.3"	"1420.7"	"1157.4"	"1797.1"	"2870.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q05397"	"Focal adhesion kinase 1 OS=Homo sapiens OX=9606 GN=PTK2 PE=1 SV=2"	"11"	"11"	"22"	"11"	"1052"	"119.2"	"6.62"	"3572.99"	"40.04"	"9"	"11"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;kinase activity;other molecular function"	"Pf00373, Pf03623, Pf07714, Pf18038"	"5747"	"ENSG00000169398"	"PTK2"	"B4E2N6; F5H4S4; hsa:5747; J3QT16; Q05397; Q14291; Q8IYN9; Q9UD85"	"Androgen receptor signaling pathway; Integrin-mediated cell adhesion; RANKL/RANK signaling pathway; Leptin signaling pathway; Prolactin signaling pathway; Corticotropin-releasing hormone signaling pathway; Alpha 6 beta 4 signaling pathway; Primary focal segmental glomerulosclerosis (FSGS); Apoptosis-related network due to altered Notch3 in ovarian cancer; Focal adhesion; Hepatocyte growth factor receptor signaling; Overview of nanoparticle effects; MFAP5-mediated ovarian cancer cell motility and invasiveness; RAC1/PAK1/p38/MMP2 pathway; Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Prion disease pathway; PI3K-Akt signaling pathway; EGF/EGFR signaling pathway; Hippo-Merlin signaling dysregulation; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Small cell lung cancer; Gastrin signaling pathway; Netrin-UNC5B signaling pathway; Pleural mesothelioma; Regulation of actin cytoskeleton; 2q13 copy number variation syndrome; TROP2 regulatory signaling; A network map of Macrophage-stimulating protein (MSP) signaling; ErbB signaling pathway"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Signal regulatory protein family interactions; EPHB-mediated forward signaling; DCC mediated attractive signaling; RAF/MAP kinase cascade; VEGFA-VEGFR2 Pathway; Estrogen-dependent nuclear events downstream of ESR-membrane signaling; NCAM signaling for neurite out-growth; MET activates PTK2 signaling; GRB2:SOS provides linkage to MAPK signaling for Integrins ; p130Cas linkage to MAPK signaling for integrins; Apoptotic cleavage of cellular proteins"	"48"	"0"	"450.4"	"249.9"	"403.7"	"420.8"	"466.5"	"495.3"	"1070.4"	"1698.6"	"2551.0"	"4489.8"	"5604.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VT25"	"Serine/threonine-protein kinase MRCK alpha OS=Homo sapiens OX=9606 GN=CDC42BPA PE=1 SV=1"	"9"	"13"	"24"	"13"	"1732"	"197.2"	"6.58"	"4900.40"	"39.99"	"12"	"10"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00130, Pf00433, Pf00780, Pf08826, Pf15796"	"8476"	"ENSG00000143776"	"CDC42BPA"	"hsa:8476; O75039; Q59GZ1; Q5H9N9; Q5T797; Q5VT25; Q5VT26; Q5VT27; Q86XX2; Q86XX3; Q99646"	"Male infertility"	"CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHOJ GTPase cycle"	"5"	"0"	"332.9"	"215.6"	"322.4"	"315.5"	"390.4"	"373.9"	"936.7"	"1489.7"	"1413.9"	"2441.3"	"2689.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99986"	"Serine/threonine-protein kinase VRK1 OS=Homo sapiens OX=9606 GN=VRK1 PE=1 SV=1"	"29"	"12"	"26"	"12"	"396"	"45.4"	"8.91"	"4106.19"	"39.91"	"11"	"12"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;ER/Golgi;nucleus"	"kinase activity;other molecular function"	"Pf00069"	"7443"	"ENSG00000100749"	"VRK1"	"hsa:7443; Q3SYL2; Q99986"	""	"Nuclear Envelope Breakdown; Initiation of Nuclear Envelope (NE) Reformation"	"2"	"0"	"292.3"	"197.7"	"289.4"	"253.7"	"334.2"	"339.8"	"2854.9"	"2951.7"	"2353.2"	"4439.2"	"6970.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3F4"	"Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1"	"31"	"9"	"24"	"9"	"350"	"38.4"	"5.12"	"4889.05"	"39.86"	"9"	"9"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00400"	"11171"	"ENSG00000023734"	"STRAP"	"B2R5S5; B4DNJ6; hsa:11171; Q5TZT4; Q9NTK0; Q9UQC8; Q9Y3F4"	"Epithelial to mesenchymal transition in colorectal cancer"	"Downregulation of TGF-beta receptor signaling"	"2"	"0"	"1268.3"	"757.6"	"1157.2"	"1140.6"	"1136.6"	"1292.1"	"1772.6"	"1615.0"	"1091.8"	"1878.1"	"2587.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07814"	"Bifunctional glutamate/proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5"	"10"	"13"	"19"	"13"	"1512"	"170.5"	"7.33"	"2029.37"	"39.76"	"7"	"11"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00043, Pf00458, Pf00587, Pf00749, Pf03129, Pf03950, Pf09180"	"2058"	"ENSG00000136628"	"EPRS1"	"A0AVA9; B9EGH3; hsa:2058; P07814; Q05BP6; Q05DF8; Q5DSM1; Q5H9S5; Q6PD57; Q86X73"	"Parkinson's disease pathway; VEGFA-VEGFR2 signaling; Amino acid metabolism"	"tRNA modification in the nucleus and cytosol; Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"6"	"0"	"1108.2"	"662.3"	"843.2"	"1004.7"	"926.3"	"1256.7"	"1830.1"	"1700.2"	"1256.5"	"1945.2"	"2452.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75475"	"PC4 and SFRS1-interacting protein OS=Homo sapiens OX=9606 GN=PSIP1 PE=1 SV=1"	"25"	"12"	"23"	"12"	"530"	"60.1"	"9.13"	"4192.49"	"39.57"	"10"	"11"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00855, Pf11467"	"11168"	"ENSG00000164985"	"PSIP1"	"D3DRI9; hsa:11168; O00256; O75475; O95368; Q6P391; Q86YB9; Q9NZI3; Q9UER6"	"MECP2 and associated Rett syndrome"	"Vpr-mediated nuclear import of PICs; Formation of WDR5-containing histone-modifying complexes; 2-LTR circle formation; Integration of viral DNA into host genomic DNA; Autointegration results in viral DNA circles; APOBEC3G mediated resistance to HIV-1 infection"	"8"	"0"	"611.8"	"312.6"	"513.9"	"494.1"	"498.7"	"538.7"	"2073.6"	"1819.7"	"1289.9"	"2285.0"	"3501.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11171"	"Protein 4.1 OS=Homo sapiens OX=9606 GN=EPB41 PE=1 SV=4"	"14"	"13"	"25"	"12"	"864"	"97.0"	"5.58"	"4082.05"	"39.54"	"11"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf04382, Pf05902, Pf08736, Pf09379, Pf09380"	"2035"	"ENSG00000159023"	"EPB41"	"B1ALH8; B1ALH9; D3DPM9; D3DPN0; hsa:2035; P11171; P11176; Q14245; Q5TB35; Q5VXN8; Q8IXV9; Q9Y578; Q9Y579"	"VEGFA-VEGFR2 signaling; Splicing factor NOVA regulated synaptic proteins; IL-18 signaling pathway"	"Neurexins and neuroligins"	"4"	"0"	"1068.6"	"554.0"	"835.7"	"928.7"	"862.4"	"1074.8"	"2608.7"	"2498.7"	"1951.6"	"3938.7"	"7166.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y237"	"Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 OS=Homo sapiens OX=9606 GN=PIN4 PE=1 SV=1"	"69"	"8"	"24"	"8"	"131"	"13.8"	"9.77"	"3616.86"	"39.41"	"5"	"8"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13616"	"5303"	"ENSG00000102309"	"PIN4"	"A8E0G6; B3KXM0; F5H1P5; hsa:5303; Q0D2H3; Q3MHV0; Q52M21; Q5HYW6; Q6IRW4; Q9Y237"	""	""	"0"	"0"	"263.0"	"162.1"	"279.2"	"287.1"	"339.6"	"302.3"	"3182.2"	"3060.8"	"2597.3"	"3616.6"	"4141.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96ST2"	"Protein IWS1 homolog OS=Homo sapiens OX=9606 GN=IWS1 PE=1 SV=2"	"15"	"11"	"24"	"11"	"819"	"91.9"	"4.69"	"4496.53"	"39.40"	"10"	"10"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus"	""	"Pf08711"	"55677"	"ENSG00000163166"	"IWS1"	"hsa:55677; Q2TB65; Q6P157; Q8N3E8; Q96MI7; Q96ST2; Q9NV97; Q9NWH8"	""	"Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events"	"3"	"0"	"1153.0"	"722.2"	"1017.1"	"1089.2"	"1004.4"	"1247.1"	"2736.1"	"2450.3"	"1725.9"	"2560.9"	"3514.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62826"	"GTP-binding nuclear protein Ran OS=Homo sapiens OX=9606 GN=RAN PE=1 SV=3"	"30"	"6"	"16"	"6"	"216"	"24.4"	"7.49"	"1774.40"	"39.36"	"3"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00071"	"5901"	"ENSG00000132341"	"RAN"	"A8K3Z8; hsa:5901; P17080; P28746; P28747; P62826; Q6IPB2; Q86V08; Q8NI90; Q9CSP3; Q9CWI7; Q9CZA2; Q9UDJ5; Q9UEU9"	"Androgen receptor signaling pathway; miRNA biogenesis; 22q11.2 copy number variation syndrome"	"Rev-mediated nuclear export of HIV RNA; NEP/NS2 Interacts with the Cellular Export Machinery; Nuclear import of Rev protein; Transcriptional regulation by small RNAs; tRNA processing in the nucleus; Regulation of cholesterol biosynthesis by SREBP (SREBF); MicroRNA (miRNA) biogenesis; Postmitotic nuclear pore complex (NPC) reformation"	"11"	"0"	"800.4"	"598.2"	"813.0"	"771.2"	"700.0"	"861.3"	"1199.9"	"1164.2"	"971.5"	"1286.5"	"1696.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q05639"	"Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1"	"25"	"9"	"26"	"2"	"463"	"50.4"	"9.03"	"4259.78"	"39.33"	"7"	"9"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03143, Pf03144"	"1917"	"ENSG00000101210"	"EEF1A2"	"B5BUF3; E1P5J1; hsa:1917; P54266; Q05639; Q0VGC7"	"Translation factors"	"Eukaryotic Translation Elongation"	"2"	"0"	"200.0"	"127.9"	"173.4"	"148.2"	"151.3"	"220.6"	"489.2"	"443.5"	"365.9"	"496.9"	"736.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H078"	"Caseinolytic peptidase B protein homolog OS=Homo sapiens OX=9606 GN=CLPB PE=1 SV=1"	"21"	"11"	"18"	"11"	"707"	"78.7"	"9.01"	"2439.02"	"39.26"	"7"	"11"	"stress response;signal transduction;other biological processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf07724, Pf10431, Pf12796, Pf13857"	"81570"	"ENSG00000162129"	"CLPB"	"B4DXJ7; B4DXP7; B4DXW4; E7EWN6; F8W7P6; hsa:81570; Q8ND11; Q9H078; Q9H8Y0"	""	""	"0"	"0"	"300.2"	"190.6"	"298.1"	"276.5"	"338.7"	"378.1"	"1462.6"	"1543.2"	"1491.2"	"2561.7"	"4260.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P67809"	"Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3"	"39"	"9"	"19"	"6"	"324"	"35.9"	"9.88"	"3083.39"	"39.13"	"6"	"8"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00313"	"4904"	"ENSG00000065978"	"YBX1"	"hsa:4904; P16990; P16991; P67809; Q14972; Q15325; Q5FVF0"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; MECP2 and associated Rett syndrome; mRNA processing; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Processing of Capped Intron-Containing Pre-mRNA; mRNA Splicing - Major Pathway; SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Interferon gamma signaling; mRNA Splicing - Minor Pathway; Noncanonical activation of NOTCH3"	"10"	"3"	"732.3"	"449.9"	"633.5"	"612.2"	"647.3"	"681.7"	"1282.7"	"1068.8"	"765.3"	"1281.2"	"1614.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06899"	"Histone H2B type 1-J OS=Homo sapiens OX=9606 GN=H2BC11 PE=1 SV=3"	"53"	"8"	"22"	"2"	"126"	"13.9"	"10.32"	"3907.40"	"38.98"	"6"	"7"	"cell organization and biogenesis;stress response;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125"	"8970"	"ENSG00000124635"	"H2BC11"	"B2R4J4; hsa:8970; O60816; P06899"	""	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; Meiotic recombination; DNA Damage/Telomere Stress Induced Senescence; Nonhomologous End-Joining (NHEJ); Amyloid fiber formation; Deposition of new CENPA-containing nucleosomes at the centromere; E3 ubiquitin ligases ubiquitinate target proteins; Meiotic synapsis; HCMV Late Events; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; HCMV Early Events; Transcriptional regulation by small RNAs; B-WICH complex positively regulates rRNA expression; Formation of the beta-catenin:TCF transactivating complex; Oxidative Stress Induced Senescence; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Pre-NOTCH Transcription and Translation; Senescence-Associated Secretory Phenotype (SASP); RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; HATs acetylate histones; RNA Polymerase I Promoter Escape; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Packaging Of Telomere Ends; Condensation of Prophase Chromosomes; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	"43"	"9"	"480.0"	"438.6"	"488.0"	"461.6"	"506.6"	"566.8"	"2089.8"	"2088.0"	"1742.4"	"2208.9"	"2174.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86YQ8"	"Copine-8 OS=Homo sapiens OX=9606 GN=CPNE8 PE=1 SV=2"	"24"	"12"	"24"	"11"	"564"	"63.1"	"5.96"	"4570.42"	"38.94"	"11"	"12"	"other biological processes"	"plasma membrane;other membranes"	"other molecular function"	"Pf00168, Pf07002"	"144402"	"ENSG00000139117"	"CPNE8"	"hsa:144402; Q2TB41; Q86VY2; Q86YQ8"	""	"CDC42 GTPase cycle; RHOQ GTPase cycle; RHOD GTPase cycle; RHOJ GTPase cycle"	"4"	"1"	"857.3"	"491.5"	"942.5"	"694.6"	"886.3"	"736.7"	"2010.4"	"2004.8"	"1527.2"	"2375.5"	"3013.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51659"	"Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3"	"20"	"11"	"21"	"11"	"736"	"79.6"	"8.84"	"3266.64"	"38.93"	"8"	"11"	"other metabolic processes;developmental processes"	"cytosol;other cytoplasmic organelle"	"other molecular function"	"Pf00106, Pf01575, Pf02036"	"3295"	"ENSG00000133835"	"HSD17B4"	"B4DNV1; B4DVS5; E9PB82; F5HE57; hsa:3295; P51659"	"Androgen receptor network in prostate cancer; Steroid biosynthesis; Disorders of bile acid synthesis and biliary transport; Primary ovarian insufficiency"	"TYSND1 cleaves peroxisomal proteins; Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol; alpha-linolenic acid (ALA) metabolism; Beta-oxidation of pristanoyl-CoA; Beta-oxidation of very long chain fatty acids"	"10"	"0"	"224.8"	"168.1"	"206.2"	"178.1"	"208.8"	"203.1"	"506.9"	"480.6"	"377.6"	"625.6"	"842.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60814"	"Histone H2B type 1-K OS=Homo sapiens OX=9606 GN=H2BC12 PE=1 SV=3"	"52"	"7"	"21"	"1"	"126"	"13.9"	"10.32"	"3411.36"	"38.83"	"5"	"7"	"stress response;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125"	"85236"	"ENSG00000197903"	"H2BC12"	"A8K7P7; hsa:85236; O60814; Q2VPI7"	""	"Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Formation of the beta-catenin:TCF transactivating complex; E3 ubiquitin ligases ubiquitinate target proteins; Amyloid fiber formation; Meiotic synapsis; HCMV Late Events; HCMV Early Events; Transcriptional regulation by small RNAs; Deposition of new CENPA-containing nucleosomes at the centromere; B-WICH complex positively regulates rRNA expression; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Oxidative Stress Induced Senescence; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Pre-NOTCH Transcription and Translation; Senescence-Associated Secretory Phenotype (SASP); RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; HATs acetylate histones; RNA Polymerase I Promoter Escape; Meiotic recombination; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Packaging Of Telomere Ends; Condensation of Prophase Chromosomes; DNA Damage/Telomere Stress Induced Senescence; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; Nonhomologous End-Joining (NHEJ); RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	"43"	"0"	"166.8"	"146.1"	"145.4"	"116.6"	"127.5"	"151.7"	"576.8"	"583.4"	"460.2"	"661.1"	"688.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99623"	"Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2"	"37"	"11"	"27"	"11"	"299"	"33.3"	"9.83"	"5036.62"	"38.75"	"11"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01145"	"11331"	"ENSG00000215021"	"PHB2"	"B4DP75; hsa:11331; Q2YDA4; Q7KYU3; Q92978; Q99623"	""	"Processing of SMDT1"	"1"	"0"	"2038.8"	"1287.6"	"1557.6"	"1212.5"	"1516.7"	"1580.0"	"2603.8"	"2264.4"	"1666.7"	"3083.2"	"4383.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19388"	"DNA-directed RNA polymerases I, II, and III subunit RPABC1 OS=Homo sapiens OX=9606 GN=POLR2E PE=1 SV=4"	"49"	"8"	"22"	"8"	"210"	"24.5"	"5.95"	"3910.11"	"38.59"	"7"	"8"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01191, Pf03871"	"5434"	"ENSG00000099817"	"POLR2E"	"B2R6L4; D6W5Y1; hsa:5434; O43380; P19388; Q6PIH5; Q9BT06"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"mRNA Splicing - Major Pathway; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Transcriptional regulation by small RNAs; B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; RNA Polymerase I Promoter Escape; Inhibition of DNA recombination at telomere; RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; Viral Messenger RNA Synthesis; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Transcription Termination; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM"	"57"	"0"	"599.4"	"376.5"	"536.1"	"553.6"	"546.2"	"630.4"	"1315.9"	"1806.2"	"1724.2"	"2877.1"	"3698.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75131"	"Copine-3 OS=Homo sapiens OX=9606 GN=CPNE3 PE=1 SV=1"	"24"	"9"	"17"	"8"	"537"	"60.1"	"5.85"	"2290.97"	"38.52"	"7"	"9"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf00168, Pf07002"	"8895"	"ENSG00000085719"	"CPNE3"	"A8KA47; hsa:8895; O75131; Q8IYA1"	""	"Neutrophil degranulation; Glycerophospholipid biosynthesis"	"2"	"0"	"492.8"	"411.9"	"566.9"	"416.8"	"486.6"	"478.9"	"696.0"	"610.3"	"455.2"	"820.1"	"1385.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15020"	"Spectrin beta chain, non-erythrocytic 2 OS=Homo sapiens OX=9606 GN=SPTBN2 PE=1 SV=3"	"6"	"13"	"26"	"7"	"2390"	"271.2"	"6.11"	"5005.42"	"38.03"	"13"	"12"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00435, Pf15410"	"6712"	"ENSG00000173898"	"SPTBN2"	"hsa:6712; O14872; O14873; O15020"	""	"MHC class II antigen presentation; COPI-mediated anterograde transport; RAF/MAP kinase cascade; NCAM signaling for neurite out-growth; Interaction between L1 and Ankyrins"	"5"	"0"	"134.9"	"81.0"	"120.8"	"104.8"	"133.2"	"151.2"	"275.2"	"267.4"	"235.9"	"425.8"	"593.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22234"	"Multifunctional protein ADE2 OS=Homo sapiens OX=9606 GN=PAICS PE=1 SV=3"	"29"	"11"	"24"	"11"	"425"	"47.0"	"7.23"	"4025.08"	"37.89"	"10"	"9"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00731, Pf01259"	"10606"	"ENSG00000128050"	"PAICS"	"E9PDH9; hsa:10606; P22234; Q68CQ5"	"Metabolic reprogramming in colon cancer"	"Purine ribonucleoside monophosphate biosynthesis"	"2"	"0"	"1570.4"	"950.0"	"1338.3"	"1164.0"	"1199.5"	"1291.3"	"1831.1"	"1708.8"	"1274.4"	"1981.7"	"3463.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62081"	"40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1"	"53"	"9"	"17"	"9"	"194"	"22.1"	"10.10"	"2802.00"	"37.85"	"6"	"8"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf01251"	"6201"	"ENSG00000171863"	"RPS7"	"hsa:6201; P23821; P24818; P62081; Q57Z92; Q6IPH1"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery; rRNA modification in the nucleus and cytosol"	"20"	"0"	"1063.7"	"662.0"	"940.0"	"652.2"	"832.1"	"821.0"	"2286.6"	"2107.2"	"1548.6"	"2281.9"	"2927.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18124"	"60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1"	"33"	"9"	"23"	"9"	"248"	"29.2"	"10.65"	"4415.29"	"37.83"	"9"	"8"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00327, Pf08079"	"6129"	"ENSG00000147604"	"RPL7"	"A8K504; hsa:6129; P18124; Q15289; Q3KQU0; Q5I0X1; Q6IBM9"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"677.5"	"475.4"	"577.6"	"515.7"	"578.5"	"628.2"	"2020.0"	"1876.7"	"1252.3"	"2139.0"	"2707.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86YS7"	"C2 domain-containing protein 5 OS=Homo sapiens OX=9606 GN=C2CD5 PE=1 SV=1"	"14"	"13"	"23"	"13"	"1000"	"110.4"	"5.69"	"3745.41"	"37.80"	"10"	"11"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00168"	"9847"	"ENSG00000111731"	"C2CD5"	"B4DJ03; B4DRN7; B7ZLL0; F5H2A1; F5H5R1; hsa:9847; O60280; Q17RY7; Q7Z619; Q86SU3; Q86YS7"	""	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"	"1"	"0"	"233.0"	"147.0"	"248.3"	"228.6"	"241.9"	"264.3"	"1323.8"	"3069.1"	"3395.5"	"5510.4"	"6784.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P47897"	"Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1"	"16"	"10"	"23"	"10"	"775"	"87.7"	"7.15"	"3511.14"	"37.72"	"10"	"10"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;mitochondrion;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00749, Pf03950, Pf04557, Pf04558"	"5859"	"ENSG00000172053"	"QARS1"	"B4DWJ2; hsa:5859; P47897"	""	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation; Mitochondrial tRNA aminoacylation"	"3"	"0"	"300.9"	"198.8"	"327.8"	"294.5"	"303.1"	"313.3"	"567.6"	"551.1"	"428.0"	"605.8"	"845.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5BKZ1"	"DBIRD complex subunit ZNF326 OS=Homo sapiens OX=9606 GN=ZNF326 PE=1 SV=2"	"22"	"11"	"24"	"11"	"582"	"65.6"	"5.15"	"4450.67"	"37.62"	"10"	"9"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04988"	"284695"	"ENSG00000162664"	"ZNF326"	"A8MYX1; B4DLN0; B4E179; hsa:284695; Q5BKZ1; Q5VW93; Q5VW94; Q5VW96; Q5VW97; Q6NSA2; Q7Z638; Q7Z6C2"	""	""	"0"	"0"	"1143.6"	"780.7"	"1140.4"	"1134.1"	"1174.3"	"1344.5"	"2128.0"	"1739.3"	"1196.7"	"2304.6"	"2869.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30153"	"Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4"	"19"	"13"	"28"	"13"	"589"	"65.3"	"5.11"	"4988.70"	"37.59"	"12"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02985"	"5518"	"ENSG00000105568"	"PPP2R1A"	"hsa:5518; P30153; Q13773; Q6ICQ3; Q96DH3"	"Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Wnt signaling pathway and pluripotency; PI3K-Akt signaling pathway; 16p11.2 proximal deletion syndrome; Glycogen synthesis and degradation; Cohesin complex - Cornelia de Lange syndrome"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Cyclin A/B1/B2 associated events during G2/M transition; Recruitment of mitotic centrosome proteins and complexes; Negative regulation of MAPK pathway; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Regulation of TP53 Degradation; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Cyclin D associated events in G1; Disassembly of the destruction complex and recruitment of AXIN to the membrane; RAF activation; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; APC truncation mutants have impaired AXIN binding; AXIN missense mutants destabilize the destruction complex; Truncations of AMER1 destabilize the destruction complex; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Spry regulation of FGF signaling; MASTL Facilitates Mitotic Progression; Regulation of glycolysis by fructose 2,6-bisphosphate metabolism; Initiation of Nuclear Envelope (NE) Reformation; Platelet sensitization by LDL; CTLA4 inhibitory signaling; Inhibition of replication initiation of damaged DNA by RB1/E2F1; DARPP-32 events; PP2A-mediated dephosphorylation of key metabolic factors; ERKs are inactivated"	"49"	"0"	"1643.4"	"910.1"	"1589.6"	"1556.6"	"1520.3"	"1735.8"	"2516.5"	"2390.2"	"1761.9"	"2536.7"	"3633.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P39748"	"Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1 PE=1 SV=1"	"34"	"10"	"20"	"10"	"380"	"42.6"	"8.62"	"3559.79"	"37.53"	"9"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00752, Pf00867"	"2237"	"ENSG00000168496"	"FEN1"	"hsa:2237; P39748"	"Base excision repair; DNA repair pathways, full network"	"HDR through MMEJ (alt-NHEJ); Early Phase of HIV Life Cycle; POLB-Dependent Long Patch Base Excision Repair; PCNA-Dependent Long Patch Base Excision Repair; Removal of the Flap Intermediate; Removal of the Flap Intermediate from the C-strand"	"8"	"0"	"298.3"	"207.7"	"320.3"	"309.0"	"329.3"	"367.3"	"2856.7"	"2658.9"	"1994.6"	"3177.3"	"4668.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43719"	"HIV Tat-specific factor 1 OS=Homo sapiens OX=9606 GN=HTATSF1 PE=1 SV=1"	"18"	"12"	"24"	"12"	"755"	"85.8"	"4.40"	"4866.97"	"37.41"	"12"	"11"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf00076"	"27336"	"ENSG00000102241"	"HTATSF1"	"D3DWG9; hsa:27336; O43719; Q59G06; Q99730"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"1220.3"	"640.6"	"902.1"	"857.6"	"868.2"	"943.0"	"3360.4"	"3037.6"	"2189.3"	"3198.3"	"4541.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A6NHR9"	"Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2"	"8"	"12"	"23"	"12"	"2005"	"226.2"	"7.30"	"4409.71"	"37.17"	"11"	"10"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06470, Pf13589"	"23347"	"ENSG00000101596"	"SMCHD1"	"A6NHR9; hsa:23347; O75141; Q6AHX6; Q6ZTQ8; Q9H6Q2; Q9UG39"	""	""	"0"	"0"	"314.3"	"197.8"	"322.7"	"283.5"	"324.9"	"334.0"	"1115.6"	"1019.9"	"722.1"	"1066.3"	"1285.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14854"	"Cytochrome c oxidase subunit 6B1 OS=Homo sapiens OX=9606 GN=COX6B1 PE=1 SV=2"	"76"	"7"	"15"	"7"	"86"	"10.2"	"7.05"	"2243.91"	"37.10"	"5"	"7"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf02297"	"1340"	"ENSG00000126267"	"COX6B1"	"B2R5C9; hsa:1340; P14854; Q6IBL4"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly; 5q35 copy number variation"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"7"	"0"	"708.0"	"320.6"	"440.1"	"482.3"	"393.1"	"507.2"	"680.7"	"641.0"	"560.6"	"787.2"	"1021.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13573"	"SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1"	"26"	"11"	"21"	"11"	"536"	"61.5"	"9.52"	"4150.95"	"37.05"	"10"	"9"	"RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus"	"signal transduction activity or receptor binding;other molecular function"	"Pf02731"	"22938"	"ENSG00000100603"	"SNW1"	"A8K8A9; hsa:22938; Q13483; Q13573; Q32N03; Q5D0D6"	"Novel intracellular components of RIG-I-like receptor pathway; Splicing factor NOVA regulated synaptic proteins; Notch signaling pathway"	"mRNA Splicing - Major Pathway; Formation of paraxial mesoderm; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Pre-NOTCH Transcription and Translation; Downregulation of SMAD2/3:SMAD4 transcriptional activity; NOTCH1 Intracellular Domain Regulates Transcription; Notch-HLH transcription pathway; NOTCH3 Intracellular Domain Regulates Transcription; Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells; NOTCH4 Intracellular Domain Regulates Transcription; RUNX3 regulates NOTCH signaling"	"15"	"0"	"970.3"	"614.6"	"811.5"	"726.6"	"828.4"	"912.3"	"2044.8"	"1844.2"	"1422.0"	"2278.7"	"2814.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62269"	"40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3"	"45"	"11"	"26"	"11"	"152"	"17.7"	"10.99"	"5332.86"	"36.99"	"11"	"8"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00416"	"6222"	"ENSG00000096150; ENSG00000223367; ENSG00000226225; ENSG00000231500; ENSG00000235650"	"RPS18"	"hsa:6222; P25232; P62269; Q5SUJ3; Q6IPF8"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"1514.1"	"1087.5"	"1286.0"	"1199.6"	"1298.1"	"1396.4"	"3637.2"	"3572.2"	"2499.8"	"3436.5"	"4520.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13242"	"Serine/arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1"	"45"	"12"	"25"	"11"	"221"	"25.5"	"8.65"	"4466.86"	"36.84"	"11"	"11"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00076"	"8683"	"ENSG00000111786"	"SRSF9"	"hsa:8683; Q13242; Q52LD1"	"mRNA processing"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"6"	"1"	"1656.6"	"1290.8"	"1756.5"	"1915.4"	"1825.4"	"2203.0"	"3984.2"	"3851.1"	"2463.6"	"2818.9"	"3168.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01085"	"Nucleolysin TIAR OS=Homo sapiens OX=9606 GN=TIAL1 PE=1 SV=1"	"27"	"9"	"23"	"6"	"375"	"41.6"	"7.74"	"3823.04"	"36.83"	"8"	"8"	"cell cycle OR cell proliferation;stress response;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"7073"	"ENSG00000151923"	"TIAL1"	"A8K3T0; A8K4L9; hsa:7073; Q01085"	""	"FGFR2 alternative splicing"	"1"	"3"	"1287.4"	"717.1"	"914.8"	"1145.7"	"1498.0"	"1279.8"	"2645.9"	"2630.4"	"1938.7"	"2565.3"	"2904.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75821"	"Eukaryotic translation initiation factor 3 subunit G OS=Homo sapiens OX=9606 GN=EIF3G PE=1 SV=2"	"26"	"8"	"16"	"8"	"320"	"35.6"	"6.13"	"2937.16"	"36.75"	"6"	"8"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf12353"	"8666"	"ENSG00000130811"	"EIF3G"	"hsa:8666; O14801; O75821; Q969U5"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"8"	"0"	"1073.1"	"698.7"	"935.4"	"747.7"	"852.3"	"930.4"	"1893.0"	"1690.3"	"1097.1"	"1827.8"	"2571.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q07021"	"Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1"	"39"	"6"	"17"	"6"	"282"	"31.3"	"4.84"	"3074.58"	"36.69"	"4"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;translation activity;nucleic acid binding activity;other molecular function"	"Pf02330"	"708"	"ENSG00000108561"	"C1QBP"	"hsa:708; Q07021; Q2HXR8; Q9NNY8"	"Complement system; Mesodermal commitment pathway; Ebola virus infection in host"	"RHOA GTPase cycle; RHOC GTPase cycle; Intrinsic Pathway of Fibrin Clot Formation; Apoptotic factor-mediated response; Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function"	"8"	"0"	"552.9"	"330.3"	"483.9"	"398.8"	"441.0"	"494.9"	"1169.1"	"1070.5"	"838.0"	"1252.5"	"1745.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P78347"	"General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2"	"12"	"11"	"22"	"11"	"998"	"112.3"	"6.39"	"3895.93"	"36.55"	"8"	"10"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02946"	"2969"	"ENSG00000263001"	"GTF2I"	"hsa:2969; O14743; O15359; O43546; O43588; O43589; P78347; Q75M85; Q75M86; Q75M87; Q75M88; Q86U51; Q9BSZ4"	"B cell receptor signaling pathway; 7q11.23 copy number variation syndrome; Genetic causes of porto-sinusoidal vascular disease"	""	"3"	"0"	"815.2"	"421.2"	"639.0"	"597.9"	"628.6"	"726.6"	"1766.1"	"1622.4"	"1235.8"	"1851.7"	"2686.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46013"	"Proliferation marker protein Ki-67 OS=Homo sapiens OX=9606 GN=MKI67 PE=1 SV=2"	"6"	"12"	"23"	"12"	"3256"	"358.5"	"9.45"	"3648.46"	"36.50"	"11"	"12"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00498, Pf08065, Pf15276"	"4288"	"ENSG00000148773"	"MKI67"	"hsa:4288; P46013; Q5VWH2"	"Primary focal segmental glomerulosclerosis (FSGS)"	""	"1"	"0"	"536.6"	"330.9"	"460.8"	"444.6"	"462.8"	"519.2"	"1411.5"	"1268.7"	"990.7"	"1531.8"	"2280.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53621"	"Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2"	"12"	"12"	"22"	"12"	"1224"	"138.3"	"7.66"	"3671.70"	"36.43"	"10"	"12"	"transport;signal transduction"	"non-structural extracellular;other membranes;cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00400, Pf04053, Pf06957, Pf12894"	"1314"	"ENSG00000122218"	"COPA"	"hsa:1314; P53621; Q5T201; Q8IXZ9"	""	"COPI-mediated anterograde transport; COPI-dependent Golgi-to-ER retrograde traffic"	"2"	"0"	"306.1"	"232.1"	"349.9"	"333.7"	"361.5"	"401.3"	"772.1"	"718.0"	"512.8"	"771.4"	"994.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01081"	"Splicing factor U2AF 35 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF1 PE=1 SV=3"	"40"	"7"	"16"	"7"	"240"	"27.9"	"8.81"	"2797.44"	"36.39"	"5"	"7"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00642"	"102724594; 7307"	"ENSG00000160201"	"U2AF1"	"hsa:102724594; hsa:7307; Q01081; Q701P4; Q71RF1"	"mRNA processing"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"5"	"0"	"339.6"	"303.6"	"374.6"	"367.9"	"364.9"	"452.8"	"1895.8"	"1701.2"	"830.5"	"1207.1"	"1308.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62249"	"40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2"	"56"	"10"	"27"	"10"	"146"	"16.4"	"10.21"	"4874.12"	"36.32"	"9"	"9"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00380"	"6217"	"ENSG00000105193"	"RPS16"	"B2RDD5; hsa:6217; P17008; P62249"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"2067.0"	"1270.4"	"1707.7"	"1387.7"	"1562.1"	"1476.4"	"4548.8"	"4098.3"	"3028.6"	"4216.7"	"5711.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95232"	"Luc7-like protein 3 OS=Homo sapiens OX=9606 GN=LUC7L3 PE=1 SV=2"	"24"	"10"	"21"	"10"	"432"	"51.4"	"9.79"	"3532.97"	"36.07"	"10"	"10"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf03194"	"51747"	"ENSG00000108848"	"LUC7L3"	"B3KN54; D3DTY1; hsa:51747; O95232; Q6PHR9; Q9NUY0; Q9P2S7"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"1396.4"	"753.1"	"1078.5"	"840.9"	"1137.4"	"1184.1"	"2735.3"	"2284.2"	"1633.8"	"3240.2"	"4744.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07197"	"Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3"	"12"	"12"	"27"	"10"	"916"	"102.4"	"4.91"	"4499.75"	"35.79"	"12"	"11"	"cell organization and biogenesis"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00038, Pf04732"	"4741"	"ENSG00000104722"	"NEFM"	"B4DGN2; E9PBF7; hsa:4741; P07197; Q4QRK6"	"Amyotrophic lateral sclerosis (ALS); Physico-chemical features and toxicity-associated pathways; Ciliary landscape"	""	"3"	"1"	"1037.5"	"741.1"	"921.4"	"951.9"	"1029.3"	"1261.0"	"1490.2"	"1332.0"	"1012.3"	"1526.4"	"2021.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42704"	"Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3"	"10"	"12"	"21"	"12"	"1394"	"157.8"	"6.13"	"3251.35"	"35.55"	"9"	"12"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"other membranes;cytoskeleton;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf01535"	"10128"	"ENSG00000138095"	"LRPPRC"	"A0PJE3; A8K1V1; hsa:10128; P42704; Q53PC0; Q53QN7; Q6ZUD8; Q7Z7A6; Q96D84"	"Ciliary landscape"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"4"	"0"	"564.6"	"354.4"	"505.1"	"546.9"	"508.6"	"639.7"	"1063.9"	"1011.4"	"759.9"	"1066.6"	"1261.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P78527"	"DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3"	"3"	"12"	"23"	"12"	"4128"	"468.8"	"7.12"	"3526.36"	"35.46"	"11"	"12"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00454, Pf02259, Pf02260, Pf08163, Pf19704, Pf20502"	"5591"	"ENSG00000253729"	"PRKDC"	"hsa:5591; P78527; P78528; Q13327; Q13337; Q14175; Q59H99; Q7Z611; Q96SE6; Q9UME3"	"miRNA regulation of DNA damage response; Cell cycle; Retinoblastoma gene in cancer; Fas ligand pathway and stress induction of heat shock proteins; Pathways affected in adenoid cystic carcinoma; ATM signaling in development and disease ; Non-homologous end joining; Osteoblast differentiation and related diseases; DNA repair pathways, full network; DNA damage response"	"E3 ubiquitin ligases ubiquitinate target proteins; Cytosolic sensors of pathogen-associated DNA ; Nonhomologous End-Joining (NHEJ); IRF3-mediated induction of type I IFN"	"14"	"0"	"392.7"	"297.0"	"374.2"	"292.7"	"432.3"	"388.4"	"590.1"	"539.8"	"428.9"	"741.9"	"975.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46782"	"40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4"	"37"	"9"	"20"	"9"	"204"	"22.9"	"9.72"	"3517.85"	"35.42"	"9"	"8"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00177"	"6193"	"ENSG00000083845"	"RPS5"	"B2R4T2; hsa:6193; P46782; Q96BN0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"892.4"	"644.2"	"867.2"	"824.6"	"808.5"	"795.0"	"2922.2"	"2817.7"	"2044.8"	"2468.9"	"2783.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NZW5"	"MAGUK p55 subfamily member 6 OS=Homo sapiens OX=9606 GN=MPP6 PE=1 SV=2"	"24"	"12"	"26"	"11"	"540"	"61.1"	"6.18"	"4332.93"	"35.35"	"12"	"12"	"cell organization and biogenesis"	"plasma membrane;other membranes;other cell component"	""	"Pf00595, Pf00625, Pf02828, Pf07653"	"51678"	"ENSG00000105926"	"PALS2"	"A4D157; hsa:51678; Q9H0E1; Q9NZW5"	""	""	"0"	"1"	"1001.8"	"566.0"	"808.1"	"836.7"	"818.2"	"946.5"	"1716.5"	"1671.6"	"1294.7"	"1978.8"	"2657.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60174"	"Triosephosphate isomerase OS=Homo sapiens OX=9606 GN=TPI1 PE=1 SV=3"	"38"	"10"	"21"	"10"	"286"	"30.8"	"5.92"	"3702.92"	"35.29"	"9"	"10"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00121"	""	"ENSPPYG00000004207; ENSPTRG00000004595"	"TPI1"	"A0A2J8JEI5; A0A2J8JEJ3; A0A2J8TBG7; A0A6D2X563; H2NGA4"	""	""	"0"	"0"	"2037.7"	"1406.8"	"2300.1"	"942.3"	"1630.4"	"1682.5"	"1766.8"	"1150.4"	"854.0"	"1988.8"	"3021.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P39023"	"60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2"	"33"	"12"	"20"	"12"	"403"	"46.1"	"10.18"	"2687.03"	"35.19"	"8"	"10"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00297"	"6122"	"ENSG00000100316"	"RPL3"	"B2RDV9; hsa:6122; P39023; Q15548; Q5I0G0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"1474.1"	"1001.4"	"1332.9"	"1088.7"	"1287.9"	"1323.0"	"4600.3"	"4128.6"	"2678.4"	"4672.9"	"5557.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43707"	"Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2"	"12"	"8"	"18"	"5"	"911"	"104.8"	"5.44"	"3432.47"	"35.05"	"8"	"8"	"cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00307, Pf00435, Pf08726"	"81"	"ENSG00000130402; ENSG00000282844"	"ACTN4"	"A4K467; D6PXK4; hsa:81; O43707; O76048"	"Arrhythmogenic right ventricular cardiomyopathy; Primary focal segmental glomerulosclerosis (FSGS); Focal adhesion; Striated muscle contraction pathway; Ebola virus infection in host; Nephrotic syndrome; Alstrom syndrome"	"Platelet degranulation ; Nephrin family interactions"	"9"	"3"	"372.8"	"292.8"	"391.2"	"291.2"	"312.4"	"366.6"	"501.9"	"419.3"	"333.5"	"630.0"	"896.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q4VCS5"	"Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1"	"14"	"13"	"23"	"11"	"1084"	"118.0"	"7.64"	"3846.84"	"35.03"	"11"	"11"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf12240"	"154796"	"ENSG00000126016"	"AMOT"	"hsa:154796; Q4VCS5; Q504X5; Q9HD27; Q9UPT1"	"VEGFA-VEGFR2 signaling; Hippo-Merlin signaling dysregulation; Pleural mesothelioma"	""	"3"	"1"	"560.6"	"360.2"	"445.9"	"402.0"	"462.0"	"516.5"	"988.8"	"914.9"	"691.9"	"1117.2"	"1414.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62136"	"Serine/threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1"	"32"	"8"	"19"	"3"	"330"	"37.5"	"6.33"	"3421.44"	"34.82"	"7"	"8"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00149, Pf16891"	"5499"	"ENSG00000172531"	"PPP1CA"	"A6NNR3; B2R908; hsa:5499; P08129; P20653; P22802; P62136; Q07161"	"Sphingolipid pathway; Nicotine effect on dopaminergic neurons; Common pathways underlying drug addiction; Focal adhesion; VEGFA-VEGFR2 signaling; Hippo-Merlin signaling dysregulation; Fragile X syndrome; Netrin-UNC5B signaling pathway; Neuroinflammation and glutamatergic signaling"	"Triglyceride catabolism; Circadian Clock; Downregulation of TGF-beta receptor signaling; DARPP-32 events"	"13"	"4"	"432.3"	"283.6"	"503.6"	"379.4"	"377.0"	"456.6"	"1268.9"	"1259.5"	"993.6"	"1461.4"	"1685.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y383"	"Putative RNA-binding protein Luc7-like 2 OS=Homo sapiens OX=9606 GN=LUC7L2 PE=1 SV=2"	"22"	"10"	"20"	"7"	"392"	"46.5"	"10.01"	"3635.14"	"34.66"	"9"	"9"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03194"	"51631"	"ENSG00000146963"	"LUC7L2"	"B7Z500; hsa:51631; Q8IUP9; Q9NVL3; Q9NVN7; Q9UQN1; Q9Y383"	""	""	"0"	"3"	"1174.1"	"694.4"	"1033.0"	"869.6"	"1030.0"	"1205.5"	"3407.4"	"2868.0"	"1711.9"	"2969.4"	"4066.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55265"	"Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4"	"9"	"10"	"25"	"10"	"1226"	"136.0"	"8.65"	"4617.22"	"34.56"	"9"	"7"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00035, Pf02137, Pf02295"	"103"	"ENSG00000160710"	"ADAR"	"B1AQQ9; B1AQR0; D3DV76; hsa:103; O15223; O43859; O43860; P55265; Q9BYM3; Q9BYM4"	"Measles virus infection; Cytosolic DNA-sensing pathway"	"Interferon alpha/beta signaling; C6 deamination of adenosine; Formation of editosomes by ADAR proteins"	"5"	"0"	"1065.5"	"723.7"	"893.5"	"721.4"	"989.8"	"980.4"	"1610.2"	"1398.0"	"1037.2"	"1844.0"	"2456.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14566"	"DNA replication licensing factor MCM6 OS=Homo sapiens OX=9606 GN=MCM6 PE=1 SV=1"	"14"	"10"	"17"	"10"	"821"	"92.8"	"5.41"	"2348.76"	"34.37"	"6"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855, Pf18263"	"4175"	"ENSG00000076003"	"MCM6"	"B2R6H2; hsa:4175; Q13504; Q14566; Q99859"	"Cell cycle; Retinoblastoma gene in cancer; Ciliary landscape; G1 to S cell cycle control; DNA replication"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"11"	"0"	"1115.8"	"833.8"	"1191.9"	"897.4"	"1064.0"	"1145.1"	"1737.1"	"1484.0"	"1117.9"	"1744.5"	"2098.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6PI48"	"Aspartate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=DARS2 PE=1 SV=1"	"16"	"10"	"22"	"9"	"645"	"73.5"	"8.02"	"3744.08"	"34.17"	"9"	"9"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00152, Pf01336, Pf02938"	"55157"	"ENSG00000117593"	"DARS2"	"hsa:55157; Q6PI48"	""	"Mitochondrial tRNA aminoacylation"	"1"	"0"	"323.0"	"188.9"	"331.0"	"277.6"	"313.4"	"355.1"	"1493.6"	"1442.2"	"1211.2"	"1747.9"	"2194.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60256"	"Phosphoribosyl pyrophosphate synthase-associated protein 2 OS=Homo sapiens OX=9606 GN=PRPSAP2 PE=1 SV=1"	"26"	"10"	"21"	"10"	"369"	"40.9"	"7.44"	"3406.04"	"33.91"	"9"	"10"	"other metabolic processes;developmental processes"	"other cell component"	"enzyme regulator activity;other molecular function"	"Pf13793, Pf14572"	"5636"	"ENSG00000141127"	"PRPSAP2"	"B4E1M8; B4E329; B7ZKZ1; E7EMY2; hsa:5636; O60256; Q6IAS2"	""	""	"0"	"0"	"624.9"	"350.8"	"497.2"	"572.9"	"478.9"	"619.2"	"912.3"	"1058.3"	"938.6"	"1669.5"	"2492.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5X1"	"Sorting nexin-9 OS=Homo sapiens OX=9606 GN=SNX9 PE=1 SV=1"	"18"	"9"	"19"	"9"	"595"	"66.6"	"5.58"	"3782.68"	"33.84"	"9"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf00018, Pf00787, Pf10456"	"51429"	"ENSG00000130340"	"SNX9"	"hsa:51429; Q9BSI7; Q9BVM1; Q9UJH6; Q9UP20; Q9Y5X1"	""	"Clathrin-mediated endocytosis; Golgi Associated Vesicle Biogenesis"	"2"	"0"	"299.4"	"206.7"	"324.0"	"289.1"	"333.0"	"354.0"	"1068.2"	"1993.0"	"2485.9"	"4149.2"	"4702.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52948"	"Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4"	"8"	"13"	"23"	"13"	"1817"	"197.5"	"6.40"	"3980.90"	"33.71"	"11"	"12"	"cell organization and biogenesis;protein metabolism;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04096, Pf12110"	"4928"	"ENSG00000110713"	"NUP98"	"hsa:4928; P52948; Q8IUT2; Q8WYB0; Q96E54; Q9H3Q4; Q9NT02; Q9UF57; Q9UHX0; Q9Y6J4; Q9Y6J5"	"SARS-CoV-2 innate immunity evasion and cell-specific immune response"	""	"1"	"0"	"528.0"	"333.3"	"471.7"	"479.5"	"510.5"	"576.3"	"980.0"	"923.1"	"701.2"	"1071.9"	"1229.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86V81"	"THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3"	"35"	"6"	"12"	"6"	"257"	"26.9"	"11.15"	"1524.13"	"33.68"	"4"	"5"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf13865"	"10189"	""	"ALYREF"	"hsa:10189; O43672; Q86V81"	""	"mRNA Splicing - Major Pathway; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript"	"7"	"0"	"795.5"	"436.8"	"561.6"	"500.9"	"551.0"	"537.2"	"1837.0"	"1580.6"	"1084.6"	"1863.0"	"2363.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46781"	"40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3"	"35"	"11"	"25"	"11"	"194"	"22.6"	"10.65"	"4538.97"	"33.50"	"10"	"10"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00163, Pf01479"	"6203"	"ENSG00000170889; ENSG00000274005; ENSG00000274626; ENSG00000274646; ENSG00000274950; ENSG00000275323; ENSG00000277079; ENSG00000277359; ENSG00000278081; ENSG00000278270"	"RPS9"	"A9C4C1; hsa:6203; P46781; Q4QRK7; Q9BVZ0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"20"	"0"	"1343.0"	"975.0"	"1245.5"	"1056.9"	"1025.5"	"1462.2"	"3245.7"	"2991.1"	"2210.5"	"3718.0"	"5372.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13667"	"Protein disulfide-isomerase A4 OS=Homo sapiens OX=9606 GN=PDIA4 PE=1 SV=2"	"18"	"11"	"20"	"10"	"645"	"72.9"	"5.07"	"3279.63"	"33.35"	"8"	"10"	"protein metabolism;other metabolic processes;stress response;transport"	"non-structural extracellular;ER/Golgi;other cell component"	"other molecular function"	"Pf00085, Pf13848"	"9601"	"ENSG00000155660"	"PDIA4"	"A8K4K6; hsa:9601; P13667; Q549T6"	""	""	"0"	"1"	"813.3"	"517.1"	"736.5"	"636.3"	"700.7"	"730.6"	"1631.8"	"1509.7"	"1221.2"	"1702.8"	"2335.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P67775"	"Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform OS=Homo sapiens OX=9606 GN=PPP2CA PE=1 SV=1"	"35"	"7"	"14"	"7"	"309"	"35.6"	"5.54"	"2109.25"	"33.32"	"5"	"7"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00149"	"5515"	"ENSG00000113575"	"PPP2CA"	"hsa:5515; P05323; P13197; P67775"	"Sphingolipid pathway; TNF-alpha signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Dopamine metabolism; Mesodermal commitment pathway; Mesodermal commitment pathway; Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Wnt signaling pathway and pluripotency; PI3K-Akt signaling pathway; Cancer immunotherapy by CTLA4 blockade; FGFR3 signaling in chondrocyte proliferation and terminal differentiation; 16p11.2 proximal deletion syndrome; Glycogen synthesis and degradation; Cohesin complex - Cornelia de Lange syndrome"	"RAF activation; Negative regulation of MAPK pathway; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Regulation of TP53 Degradation; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Cyclin D associated events in G1; Disassembly of the destruction complex and recruitment of AXIN to the membrane; Cyclin A/B1/B2 associated events during G2/M transition; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; APC truncation mutants have impaired AXIN binding; AXIN missense mutants destabilize the destruction complex; Truncations of AMER1 destabilize the destruction complex; Spry regulation of FGF signaling; MASTL Facilitates Mitotic Progression; Regulation of glycolysis by fructose 2,6-bisphosphate metabolism; Initiation of Nuclear Envelope (NE) Reformation; Platelet sensitization by LDL; CTLA4 inhibitory signaling; Inhibition of replication initiation of damaged DNA by RB1/E2F1; DARPP-32 events; PP2A-mediated dephosphorylation of key metabolic factors; ERKs are inactivated"	"52"	"0"	"467.0"	"302.7"	"451.9"	"469.2"	"451.4"	"522.7"	"992.9"	"878.3"	"676.9"	"1275.1"	"1540.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07237"	"Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3"	"19"	"10"	"20"	"10"	"508"	"57.1"	"4.87"	"3332.16"	"33.27"	"9"	"9"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00085, Pf13848"	"5034"	"ENSG00000185624"	"P4HB"	"B2RDQ2; hsa:5034; P07237; P30037; P32079; Q15205; Q6LDE5"	"VEGFA-VEGFR2 signaling; Type I collagen synthesis in the context of osteogenesis imperfecta"	"Hedgehog ligand biogenesis; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Collagen biosynthesis and modifying enzymes; Detoxification of Reactive Oxygen Species; Insulin processing; Interleukin-12 signaling; Interleukin-23 signaling; Chylomicron assembly; VLDL assembly; LDL remodeling"	"13"	"0"	"1226.4"	"834.9"	"1282.7"	"1094.9"	"1140.8"	"1282.8"	"2005.9"	"1764.8"	"1207.1"	"2004.1"	"2988.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48735"	"Isocitrate dehydrogenase [NADP], mitochondrial OS=Homo sapiens OX=9606 GN=IDH2 PE=1 SV=2"	"19"	"8"	"18"	"8"	"452"	"50.9"	"8.69"	"3175.67"	"32.80"	"6"	"8"	"other metabolic processes"	"cytosol;mitochondrion;other cytoplasmic organelle"	"other molecular function"	"Pf00180"	"3418"	"ENSG00000182054"	"IDH2"	"B2R6L6; B4DFL2; hsa:3418; P48735; Q96GT3"	"VEGFA-VEGFR2 signaling; Metabolic reprogramming in colon cancer; Cerebral organic acidurias, including diseases; TCA cycle (aka Krebs or citric acid cycle)"	"Transcriptional activation of mitochondrial biogenesis; Citric acid cycle (TCA cycle)"	"6"	"0"	"409.6"	"269.6"	"417.5"	"374.4"	"464.1"	"442.7"	"910.9"	"922.0"	"742.6"	"1047.1"	"1454.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16630"	"Cleavage and polyadenylation specificity factor subunit 6 OS=Homo sapiens OX=9606 GN=CPSF6 PE=1 SV=2"	"19"	"7"	"15"	"7"	"551"	"59.2"	"7.15"	"2175.45"	"32.41"	"5"	"7"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00076"	"11052"	"ENSG00000111605"	"CPSF6"	"A8K7K9; hsa:11052; Q16630; Q53ES1; Q9BSJ7; Q9BW18"	""	"Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease"	"2"	"0"	"344.8"	"228.7"	"332.8"	"278.5"	"291.9"	"321.5"	"788.9"	"789.6"	"603.5"	"950.1"	"1250.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16891"	"MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1"	"15"	"12"	"22"	"12"	"758"	"83.6"	"6.48"	"3836.95"	"32.34"	"11"	"11"	"cell organization and biogenesis;other biological processes"	"other membranes;mitochondrion"	""	"Pf09731"	"10989"	"ENSG00000132305"	"IMMT"	"B1H0U5; B2R5N6; hsa:10989; Q14539; Q15092; Q16891; Q68D41; Q69HW5; Q6IBL0; Q7Z3X1; Q8TAJ5; Q9P0V2"	""	"Cristae formation"	"1"	"0"	"1688.5"	"1081.0"	"1319.2"	"889.1"	"1321.5"	"1400.4"	"1831.8"	"1313.4"	"899.0"	"2110.2"	"2748.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62241"	"40S ribosomal protein S8 OS=Homo sapiens OX=9606 GN=RPS8 PE=1 SV=2"	"45"	"9"	"19"	"9"	"208"	"24.2"	"10.32"	"2287.25"	"32.32"	"7"	"9"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01201"	"6202"	"ENSG00000142937"	"RPS8"	"hsa:6202; P09058; P62241; Q6IRL7"	"Cytoplasmic ribosomal proteins"	"Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"699.7"	"607.3"	"657.7"	"555.0"	"635.1"	"694.8"	"2120.7"	"2202.1"	"1812.5"	"2114.9"	"2117.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6UN15"	"Pre-mRNA 3'-end-processing factor FIP1 OS=Homo sapiens OX=9606 GN=FIP1L1 PE=1 SV=1"	"18"	"8"	"22"	"8"	"594"	"66.5"	"5.59"	"4472.94"	"32.31"	"8"	"7"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	""	"Pf05182"	"81608"	"ENSG00000145216"	"FIP1L1"	"B4DIR3; G3XAD6; hsa:81608; Q0VGE0; Q499Y4; Q49AU3; Q6UN15; Q7Z608; Q8WVN3; Q96F80; Q9H077"	""	"Transport of Mature mRNA Derived from an Intronless Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; Signaling by cytosolic PDGFRA and PDGFRB fusion proteins"	"6"	"0"	"703.0"	"407.5"	"563.1"	"578.1"	"564.3"	"704.5"	"1280.0"	"1209.1"	"889.5"	"1462.0"	"1845.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14776"	"Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2"	"10"	"9"	"18"	"9"	"1098"	"123.8"	"8.65"	"2834.21"	"32.27"	"8"	"9"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00397, Pf01846"	"10915"	"ENSG00000113649"	"TCERG1"	"hsa:10915; O14776; Q2NKN2; Q59EA1"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"389.9"	"283.5"	"347.6"	"331.8"	"371.3"	"411.2"	"1106.8"	"968.6"	"767.1"	"1348.1"	"1706.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P39019"	"40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2"	"35"	"7"	"21"	"7"	"145"	"16.1"	"10.32"	"3878.58"	"32.13"	"7"	"7"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01090"	"6223"	"ENSG00000105372"	"RPS19"	"hsa:6223; P39019"	"Complement system; Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"20"	"0"	"775.9"	"539.7"	"737.0"	"576.3"	"730.7"	"639.2"	"2208.0"	"2028.7"	"1667.1"	"1982.9"	"2438.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51610"	"Host cell factor 1 OS=Homo sapiens OX=9606 GN=HCFC1 PE=1 SV=2"	"7"	"13"	"22"	"13"	"2035"	"208.6"	"7.46"	"4213.17"	"32.13"	"12"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf01344, Pf13415"	"3054"	"ENSG00000172534"	"HCFC1"	"hsa:3054; P51610; Q6P4G5"	"Mitochondrial gene expression; Pleural mesothelioma"	"UCH proteinases; Formation of WDR5-containing histone-modifying complexes; Transcriptional activation of mitochondrial biogenesis; HATs acetylate histones"	"6"	"0"	"773.2"	"483.9"	"668.8"	"619.7"	"677.0"	"716.6"	"1609.1"	"1537.3"	"1119.0"	"1758.7"	"2258.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35232"	"Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1"	"37"	"9"	"21"	"9"	"272"	"29.8"	"5.76"	"4346.39"	"32.02"	"8"	"8"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01145"	"5245"	"ENSG00000167085"	"PHB1"	"B4DY47; hsa:5245; P35232; Q4VBQ0"	""	"RAF activation; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Processing of SMDT1"	"5"	"0"	"1148.5"	"827.0"	"956.8"	"734.1"	"954.0"	"992.3"	"1573.9"	"1341.9"	"963.9"	"1796.9"	"2213.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EP5"	"DAZ-associated protein 1 OS=Homo sapiens OX=9606 GN=DAZAP1 PE=1 SV=1"	"20"	"8"	"17"	"8"	"407"	"43.4"	"8.56"	"3402.06"	"32.00"	"6"	"7"	"cell cycle OR cell proliferation;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"26528"	"ENSG00000071626"	"DAZAP1"	"hsa:26528; Q96EP5; Q96MJ3; Q9NRR9"	""	""	"0"	"0"	"491.4"	"306.4"	"556.5"	"527.4"	"510.1"	"600.0"	"1402.0"	"1362.0"	"1015.1"	"1367.8"	"1454.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15637"	"Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4"	"13"	"6"	"16"	"6"	"639"	"68.3"	"8.98"	"3029.50"	"31.84"	"4"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"translational apparatus;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf00098, Pf16275"	"7536"	"ENSG00000168066"	"SF1"	"B7Z1Q1; C9JJE2; hsa:7536; Q14818; Q14819; Q15637; Q15913; Q8IY00; Q92744; Q92745; Q969H7; Q9BW01; Q9UEI0"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"543.0"	"310.1"	"410.1"	"479.1"	"479.5"	"529.7"	"1062.5"	"975.4"	"775.0"	"1186.0"	"1631.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WWY3"	"U4/U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2"	"20"	"8"	"17"	"8"	"499"	"55.4"	"5.78"	"2710.81"	"31.77"	"6"	"8"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01798, Pf09785"	"26121"	"ENSG00000105618; ENSG00000274144; ENSG00000274651; ENSG00000274894; ENSG00000275117; ENSG00000275885; ENSG00000276421; ENSG00000277154; ENSG00000277707; ENSG00000277953"	"PRPF31"	"E7ESA8; F1T0A4; F1T0A5; hsa:26121; Q17RB4; Q8N7F9; Q8WWY3; Q9H271; Q9Y439"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"772.5"	"464.4"	"574.9"	"619.1"	"670.2"	"733.4"	"1552.2"	"1354.3"	"1050.5"	"1723.2"	"2212.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06733"	"Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2"	"23"	"10"	"21"	"10"	"434"	"47.1"	"7.39"	"3161.80"	"31.76"	"8"	"10"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00113, Pf03952"	"2023"	"ENSG00000074800"	"ENO1"	"B2RD59; hsa:2023; P06733; P22712; Q16704; Q4TUS4; Q53FT9; Q53HR3; Q658M5; Q6GMP2; Q71V37; Q7Z3V6; Q8WU71; Q96GV1; Q9BT62; Q9UCH6; Q9UM55"	"Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; IL-18 signaling pathway; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"Glycolysis; Gluconeogenesis; Manipulation of host energy metabolism"	"9"	"0"	"1962.3"	"1273.0"	"2121.0"	"1139.1"	"1657.2"	"1757.2"	"1981.2"	"1450.4"	"1011.9"	"2122.1"	"3594.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42167"	"Lamina-associated polypeptide 2, isoforms beta/gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2"	"23"	"9"	"17"	"9"	"454"	"50.6"	"9.38"	"2971.31"	"31.67"	"8"	"9"	""	"other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03020, Pf08198"	"7112"	"ENSG00000120802"	"TMPO"	"A2T926; hsa:7112; P42167; Q14861"	"Envelope proteins and their potential roles in EDMD physiopathology; Overlap between signal transduction pathways contributing to LMNA laminopathies"	"RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOJ GTPase cycle; RHOG GTPase cycle; RHOD GTPase cycle; RHOF GTPase cycle"	"12"	"0"	"690.3"	"443.4"	"541.3"	"451.2"	"607.6"	"616.4"	"1163.1"	"993.7"	"758.1"	"1224.0"	"1711.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P78406"	"mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1"	"27"	"8"	"19"	"8"	"368"	"40.9"	"7.83"	"4710.50"	"31.64"	"8"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00400"	"8480"	"ENSG00000101146"	"RAE1"	"A8K882; hsa:8480; O15306; P78406; Q3SYL7; Q5TCH8; Q6V708; Q9H100; Q9NQM6"	"IL-18 signaling pathway; SARS-CoV-2 innate immunity evasion and cell-specific immune response"	"snRNP Assembly; ISG15 antiviral mechanism; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Transcriptional regulation by small RNAs; Viral Messenger RNA Synthesis; HCMV Late Events; HCMV Early Events; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus"	"30"	"0"	"1316.5"	"765.3"	"1088.8"	"1120.3"	"1143.6"	"1102.8"	"2160.4"	"2137.2"	"1536.7"	"2524.6"	"3712.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99584"	"Protein S100-A13 OS=Homo sapiens OX=9606 GN=S100A13 PE=1 SV=1"	"37"	"4"	"16"	"4"	"98"	"11.5"	"6.16"	"2461.77"	"31.55"	"2"	"4"	"transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01023"	"6284"	"ENSG00000189171"	"S100A13"	"hsa:6284; Q52PI9; Q6FGF8; Q99584"	""	""	"0"	"0"	"366.5"	"186.5"	"357.6"	"307.3"	"345.9"	"330.6"	"843.1"	"1215.5"	"885.8"	"1944.9"	"7054.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H4G4"	"Golgi-associated plant pathogenesis-related protein 1 OS=Homo sapiens OX=9606 GN=GLIPR2 PE=1 SV=3"	"55"	"7"	"14"	"7"	"154"	"17.2"	"9.41"	"2618.33"	"31.44"	"5"	"7"	"other biological processes"	"non-structural extracellular;other membranes;ER/Golgi"	"other molecular function"	"Pf00188"	"152007"	"ENSG00000122694"	"GLIPR2"	"hsa:152007; Q5VZR1; Q8N2S6; Q8WWC9; Q8WX36; Q9H4G4"	""	""	"0"	"0"	"345.6"	"219.6"	"290.9"	"280.4"	"299.8"	"332.3"	"1669.9"	"1677.1"	"1662.2"	"3176.2"	"4220.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15293"	"Reticulocalbin-1 OS=Homo sapiens OX=9606 GN=RCN1 PE=1 SV=1"	"24"	"6"	"14"	"6"	"331"	"38.9"	"5.00"	"2538.10"	"31.44"	"4"	"6"	"developmental processes"	"ER/Golgi"	"other molecular function"	"Pf13202"	"5954"	"ENSG00000049449"	"RCN1"	"B7Z1M1; D3DR00; hsa:5954; Q15293"	"VEGFA-VEGFR2 signaling"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation"	"3"	"0"	"757.5"	"266.6"	"637.1"	"755.7"	"595.1"	"832.3"	"2052.6"	"1854.3"	"1266.1"	"2009.7"	"2870.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60264"	"SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1"	"10"	"11"	"21"	"3"	"1052"	"121.8"	"8.09"	"3199.27"	"31.33"	"10"	"11"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf09110, Pf09111"	"8467"	"ENSG00000153147"	"SMARCA5"	"hsa:8467; O60264"	"10q11.21q11.23 copy number variation syndrome"	"Deposition of new CENPA-containing nucleosomes at the centromere; B-WICH complex positively regulates rRNA expression; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; NoRC negatively regulates rRNA expression"	"5"	"8"	"627.9"	"424.4"	"572.2"	"536.1"	"599.0"	"639.7"	"1735.4"	"1585.6"	"1208.8"	"2039.3"	"2613.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26373"	"60S ribosomal protein L13 OS=Homo sapiens OX=9606 GN=RPL13 PE=1 SV=4"	"36"	"9"	"18"	"9"	"211"	"24.2"	"11.65"	"2917.27"	"31.29"	"7"	"8"	"protein metabolism;other metabolic processes;developmental processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01294"	"6137"	"ENSG00000167526"	"RPL13"	"B4DLX3; F5H1S2; hsa:6137; P26373; Q3KQT8; Q567Q8; Q9BPX0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"1313.0"	"815.1"	"1052.0"	"965.5"	"1143.3"	"1160.7"	"3913.7"	"3602.1"	"2301.1"	"3698.6"	"4485.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49756"	"RNA-binding protein 25 OS=Homo sapiens OX=9606 GN=RBM25 PE=1 SV=3"	"14"	"10"	"20"	"10"	"843"	"100.1"	"6.32"	"4179.76"	"31.26"	"10"	"8"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf01480"	"58517"	"ENSG00000119707"	"RBM25"	"A0PJL9; B2RNA8; B3KT03; hsa:58517; P49756; Q2TA72; Q5XJ17; Q6P665; Q9H6A1; Q9UEQ5; Q9UIE9"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"890.0"	"429.0"	"583.4"	"563.6"	"698.5"	"705.5"	"1364.5"	"1236.3"	"1021.7"	"1770.8"	"2319.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06454"	"Prothymosin alpha OS=Homo sapiens OX=9606 GN=PTMA PE=1 SV=2"	"23"	"4"	"15"	"4"	"111"	"12.2"	"3.78"	"3375.28"	"31.13"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf03247"	"5757"	"ENSG00000187514"	"PTMA"	"hsa:5757; P06454; Q15249; Q15592"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"686.3"	"412.7"	"461.2"	"368.6"	"437.2"	"506.0"	"758.6"	"699.0"	"712.4"	"672.7"	"740.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q09028"	"Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3"	"24"	"10"	"22"	"4"	"425"	"47.6"	"4.89"	"3678.15"	"31.00"	"9"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400, Pf12265"	"5928"	"ENSG00000162521"	"RBBP4"	"B2R6G9; B4DRH0; D3DPQ3; hsa:5928; P31149; Q09028; Q53H02; Q96BV9"	"Retinoblastoma gene in cancer; Interactome of polycomb repressive complex 2 (PRC2) ; Tumor suppressor activity of SMARCB1; Epithelial to mesenchymal transition in colorectal cancer; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; Pleural mesothelioma; DYRK1A involvement regarding cell proliferation in brain development"	"RNA Polymerase I Transcription Initiation; HCMV Early Events; Potential therapeutics for SARS; Deposition of new CENPA-containing nucleosomes at the centromere; Oxidative Stress Induced Senescence; HDACs deacetylate histones; Activation of anterior HOX genes in hindbrain development during early embryogenesis; PRC2 methylates histones and DNA; Defective pyroptosis; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6; PKMTs methylate histone lysines; G1/S-Specific Transcription; Regulation of TP53 Activity through Acetylation; Polo-like kinase mediated events; Cyclin E associated events during G1/S transition ; Transcription of E2F targets under negative control by DREAM complex; Cyclin A:Cdk2-associated events at S phase entry; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"	"28"	"7"	"1274.5"	"732.7"	"984.5"	"1010.4"	"996.2"	"1140.6"	"2071.7"	"1901.0"	"1413.7"	"1999.2"	"2645.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P33991"	"DNA replication licensing factor MCM4 OS=Homo sapiens OX=9606 GN=MCM4 PE=1 SV=5"	"11"	"10"	"19"	"10"	"863"	"96.5"	"6.74"	"3187.84"	"31.00"	"9"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855"	"4173"	"ENSG00000104738"	"MCM4"	"hsa:4173; P33991; Q8NEH1; Q99658"	"Cell cycle; Gastric cancer network 1; Retinoblastoma gene in cancer; Ciliary landscape; G1 to S cell cycle control; DNA replication"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"12"	"0"	"1122.6"	"722.4"	"1018.2"	"770.3"	"884.0"	"969.8"	"1446.6"	"1282.6"	"933.1"	"1455.4"	"1861.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14927"	"Cytochrome b-c1 complex subunit 7 OS=Homo sapiens OX=9606 GN=UQCRB PE=1 SV=2"	"55"	"6"	"16"	"6"	"111"	"13.5"	"8.78"	"3854.93"	"30.95"	"6"	"6"	"other metabolic processes;transport"	"other membranes;mitochondrion"	""	"Pf02271"	"7381"	"ENSG00000156467"	"UQCRB"	"E5RJU0; hsa:7381; P14927; Q6FGD1"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex III assembly"	"Respiratory electron transport"	"4"	"0"	"288.2"	"168.5"	"226.5"	"280.4"	"255.6"	"335.8"	"1428.9"	"1427.5"	"1081.0"	"1490.4"	"1596.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16576"	"Histone-binding protein RBBP7 OS=Homo sapiens OX=9606 GN=RBBP7 PE=1 SV=1"	"18"	"9"	"22"	"3"	"425"	"47.8"	"5.05"	"4199.45"	"30.91"	"9"	"7"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400, Pf12265"	"5931"	"ENSG00000102054"	"RBBP7"	"hsa:5931; Q16576; Q5JP00"	"Retinoblastoma gene in cancer; Interactome of polycomb repressive complex 2 (PRC2) ; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"HCMV Early Events; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Neddylation; Potential therapeutics for SARS; Deposition of new CENPA-containing nucleosomes at the centromere; Oxidative Stress Induced Senescence; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6; HDACs deacetylate histones; RMTs methylate histone arginines; PKMTs methylate histone lysines; HATs acetylate histones; RNA Polymerase I Transcription Initiation; PRC2 methylates histones and DNA; Defective pyroptosis; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of TP53 Activity through Acetylation"	"20"	"0"	"296.3"	"163.1"	"214.2"	"234.6"	"209.7"	"240.6"	"468.7"	"424.7"	"304.7"	"489.9"	"559.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43776"	"Asparagine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=NARS1 PE=1 SV=1"	"21"	"12"	"22"	"12"	"548"	"62.9"	"6.25"	"5527.62"	"30.88"	"11"	"8"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00152, Pf01336"	"4677"	"ENSG00000134440"	"NARS1"	"B4DG16; hsa:4677; O43776; Q53GU6"	"Photodynamic therapy-induced unfolded protein response"	"Cytosolic tRNA aminoacylation"	"2"	"0"	"273.3"	"178.7"	"321.5"	"308.2"	"321.1"	"380.1"	"797.1"	"882.5"	"1200.8"	"3087.0"	"6304.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94906"	"Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1"	"12"	"12"	"24"	"12"	"941"	"106.9"	"8.25"	"4149.44"	"30.78"	"12"	"10"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf06424, Pf13181"	"24148"	"ENSG00000101161"	"PRPF6"	"B2RAR5; B3KMC6; hsa:24148; O94906; O95109; Q5VXS5; Q9H3Z1; Q9H4T9; Q9H4U8; Q9NTE6"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"0"	"1009.1"	"669.0"	"931.5"	"789.6"	"978.9"	"974.8"	"2202.1"	"2101.9"	"1568.3"	"2528.0"	"3085.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01844"	"RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1"	"14"	"6"	"16"	"6"	"656"	"68.4"	"9.33"	"2793.62"	"30.65"	"4"	"6"	"other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00076, Pf00641"	"2130"	"ENSG00000182944"	"EWSR1"	"B0QYK1; hsa:2130; Q01844; Q5THL0; Q92635; Q96FE8; Q96MN4; Q96MX4; Q9BWA2"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"634.7"	"453.4"	"607.4"	"458.8"	"547.0"	"527.2"	"1324.7"	"1337.1"	"1235.4"	"1334.6"	"1499.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52209"	"6-phosphogluconate dehydrogenase, decarboxylating OS=Homo sapiens OX=9606 GN=PGD PE=1 SV=3"	"19"	"9"	"17"	"9"	"483"	"53.1"	"7.23"	"2451.07"	"30.56"	"7"	"9"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00393, Pf03446"	"5226"	"ENSG00000142657"	"PGD"	"A8K2Y9; B4DQJ8; hsa:5226; P52209; Q9BWD8"	"Pentose phosphate metabolism; Nuclear receptors meta-pathway; NRF2 pathway; VEGFA-VEGFR2 signaling; Metabolic reprogramming in colon cancer"	"NFE2L2 regulates pentose phosphate pathway genes; Pentose phosphate pathway"	"7"	"0"	"1027.7"	"626.2"	"866.4"	"855.1"	"959.9"	"1025.4"	"1294.3"	"1265.7"	"1078.0"	"2038.0"	"3939.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62937"	"Peptidyl-prolyl cis-trans isomerase A OS=Homo sapiens OX=9606 GN=PPIA PE=1 SV=2"	"45"	"9"	"23"	"9"	"165"	"18.0"	"7.81"	"4426.45"	"30.54"	"8"	"7"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00160"	"5478"	"ENSG00000196262"	"PPIA"	"A8K220; hsa:5478; P05092; P62937; Q3KQW3; Q567Q0; Q6IBU5; Q96IX3; Q9BRU4; Q9BTY9; Q9UC61"	"Prolactin signaling pathway"	"Neutrophil degranulation; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Budding and maturation of HIV virion; Platelet degranulation ; Basigin interactions; SARS-CoV-1 activates/modulates innate immune responses; Integration of provirus; APOBEC3G mediated resistance to HIV-1 infection; Calcineurin activates NFAT; Binding and entry of HIV virion; Assembly Of The HIV Virion; Uncoating of the HIV Virion; Minus-strand DNA synthesis; Plus-strand DNA synthesis"	"16"	"0"	"2456.2"	"1716.9"	"2671.4"	"1406.8"	"2066.2"	"2181.9"	"2412.1"	"1808.6"	"1442.0"	"2508.8"	"4458.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43143"	"Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2"	"9"	"10"	"19"	"10"	"795"	"90.9"	"7.46"	"3020.79"	"30.52"	"9"	"9"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"1665"	"ENSG00000109606"	"DHX15"	"hsa:1665; O43143; Q9NQT7"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"456.0"	"310.9"	"500.3"	"335.5"	"454.0"	"448.5"	"944.0"	"828.5"	"635.7"	"1117.6"	"1248.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5S9"	"RNA-binding protein 8A OS=Homo sapiens OX=9606 GN=RBM8A PE=1 SV=1"	"31"	"3"	"13"	"3"	"174"	"19.9"	"5.72"	"4227.76"	"30.50"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"9939"	"ENSG00000265241"	"RBM8A"	"B3KQI9; hsa:9939; Q6FHD1; Q6IQ40; Q9GZX8; Q9NZI4; Q9Y5S9"	""	"mRNA Splicing - Major Pathway; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing"	"6"	"0"	"120.0"	"101.0"	"106.3"	"83.1"	"109.9"	"131.1"	"211.9"	"169.6"	"147.5"	"301.6"	"373.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P78371"	"T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4"	"23"	"11"	"20"	"11"	"535"	"57.5"	"6.46"	"3878.84"	"30.45"	"9"	"8"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00118"	"10576"	"ENSG00000166226"	"CCT2"	"A8K402; B5BTY7; B7Z243; B7Z7K4; B7ZAT2; hsa:10576; P78371; Q14D36; Q6IAT3"	"16p11.2 proximal deletion syndrome"	"Neutrophil degranulation; Formation of tubulin folding intermediates by CCT/TriC; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; RHOBTB2 GTPase cycle; Folding of actin by CCT/TriC; BBSome-mediated cargo-targeting to cilium; RHOBTB1 GTPase cycle"	"10"	"0"	"774.3"	"567.4"	"782.0"	"669.6"	"755.9"	"832.0"	"1120.5"	"1077.8"	"834.8"	"1206.6"	"1583.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08559"	"Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Homo sapiens OX=9606 GN=PDHA1 PE=1 SV=3"	"26"	"10"	"24"	"10"	"390"	"43.3"	"8.06"	"4523.97"	"30.32"	"10"	"9"	"other metabolic processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00676"	"5160"	"ENSG00000131828"	"PDHA1"	"A5YVE9; B2R5P7; B7Z3T7; B7Z3X5; hsa:5160; P08559; Q53H41; Q5JPT8; Q9NP12; Q9UBJ8; Q9UBU0; Q9UNG4; Q9UNG5"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Lipid metabolism pathway; PI3K/AKT/mTOR - vitamin D3 signaling; Metabolic reprogramming in colon cancer; Thiamine metabolic pathways; TCA cycle in senescence; Neuroinflammation and glutamatergic signaling; Acetylcholine synthesis; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"Glyoxylate metabolism and glycine degradation; Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid"	"15"	"0"	"1665.1"	"1158.1"	"1763.4"	"1487.9"	"1731.6"	"1691.0"	"3153.0"	"3013.8"	"2252.4"	"3060.5"	"3781.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12532"	"Creatine kinase U-type, mitochondrial OS=Homo sapiens OX=9606 GN=CKMT1A PE=1 SV=1"	"25"	"9"	"16"	"9"	"417"	"47.0"	"8.34"	"2652.26"	"30.28"	"6"	"6"	"other metabolic processes"	"other membranes;mitochondrion"	"kinase activity;other molecular function"	"Pf00217, Pf02807"	"1159; 548596"	"ENSG00000223572; ENSG00000237289"	"CKMT1A; CKMT1B"	"B4DIT8; B7ZA09; hsa:1159; hsa:548596; P12532; Q0VAM3; Q32NF6; Q53FC4"	""	"Creatine metabolism"	"1"	"0"	"474.3"	"353.4"	"432.4"	"364.2"	"416.4"	"443.2"	"2315.9"	"2296.8"	"1862.3"	"2518.1"	"3346.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15042"	"U2 snRNP-associated SURP motif-containing protein OS=Homo sapiens OX=9606 GN=U2SURP PE=1 SV=2"	"11"	"10"	"19"	"9"	"1029"	"118.2"	"8.47"	"3111.58"	"30.25"	"9"	"10"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf00076, Pf01805, Pf04818, Pf08312"	"23350"	"ENSG00000163714"	"U2SURP"	"A0PJ60; hsa:23350; O15042; Q0D2M1; Q2NKQ7; Q9BR70"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"1052.4"	"662.3"	"825.7"	"728.7"	"877.0"	"842.2"	"1688.1"	"1356.1"	"894.3"	"1561.9"	"2153.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62263"	"40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3"	"40"	"5"	"12"	"5"	"151"	"16.3"	"10.05"	"2115.31"	"30.18"	"4"	"5"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00411"	"6208"	"ENSG00000164587"	"RPS14"	"B2R5G5; D3DQG5; hsa:6208; P06366; P62263; Q5BJI0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; rRNA modification in the nucleus and cytosol; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"20"	"0"	"460.5"	"333.2"	"481.8"	"383.2"	"420.1"	"387.4"	"1006.2"	"919.8"	"717.1"	"1058.9"	"1384.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P41091"	"Eukaryotic translation initiation factor 2 subunit 3 OS=Homo sapiens OX=9606 GN=EIF2S3 PE=1 SV=3"	"22"	"8"	"14"	"8"	"472"	"51.1"	"8.40"	"2205.99"	"30.18"	"5"	"8"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03144, Pf09173"	"1968"	"ENSG00000130741"	"EIF2S3"	"A0A024RBY4; A8K2Y2; B2R5N2; B5BTZ4; hsa:1968; P41091; Q53HK3"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"PERK regulates gene expression; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; ABC-family proteins mediated transport; Formation of the ternary complex, and subsequently, the 43S complex; Response of EIF2AK1 (HRI) to heme deficiency; Recycling of eIF2:GDP; Response of EIF2AK4 (GCN2) to amino acid deficiency"	"12"	"0"	"409.3"	"256.6"	"394.7"	"325.1"	"421.1"	"414.2"	"1263.4"	"1295.4"	"943.3"	"2002.1"	"3386.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N7H5"	"RNA polymerase II-associated factor 1 homolog OS=Homo sapiens OX=9606 GN=PAF1 PE=1 SV=2"	"22"	"10"	"18"	"10"	"531"	"59.9"	"4.63"	"3720.17"	"30.07"	"9"	"8"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf03985"	"54623"	"ENSG00000006712"	"PAF1"	"hsa:54623; M0QX35; O75239; Q8N7H5; Q9H166; Q9NUU9"	"Endoderm differentiation"	"RNA Polymerase II Pre-transcription Events; E3 ubiquitin ligases ubiquitinate target proteins; Formation of RNA Pol II elongation complex"	"5"	"0"	"596.7"	"404.0"	"529.0"	"499.8"	"546.4"	"561.7"	"1827.6"	"1638.4"	"1140.1"	"1782.5"	"2280.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86VM9"	"Zinc finger CCCH domain-containing protein 18 OS=Homo sapiens OX=9606 GN=ZC3H18 PE=1 SV=2"	"11"	"12"	"23"	"12"	"953"	"106.3"	"8.32"	"3687.20"	"30.07"	"12"	"11"	"other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf18044"	"124245"	"ENSG00000158545"	"ZC3H18"	"hsa:124245; Q86VM9; Q96DG4; Q96MP7"	""	""	"0"	"0"	"643.4"	"399.2"	"479.1"	"516.4"	"538.8"	"601.0"	"5238.0"	"4871.5"	"3718.4"	"4838.4"	"5747.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P78356"	"Phosphatidylinositol 5-phosphate 4-kinase type-2 beta OS=Homo sapiens OX=9606 GN=PIP4K2B PE=1 SV=1"	"19"	"7"	"17"	"7"	"416"	"47.3"	"7.33"	"2947.95"	"30.06"	"6"	"7"	"cell organization and biogenesis;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle"	"kinase activity;other molecular function"	"Pf01504"	"8396"	"ENSG00000276293; ENSG00000277292"	"PIP4K2B"	"hsa:8396; P78356; Q5U0E8; Q8TBP2"	"Regulation of actin cytoskeleton; 17q12 copy number variation syndrome"	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Synthesis of PIPs at the plasma membrane; PI5P Regulates TP53 Acetylation; Synthesis of PIPs in the nucleus"	"6"	"0"	"206.6"	"128.8"	"215.5"	"215.8"	"269.1"	"245.6"	"814.0"	"1187.1"	"1291.9"	"2616.1"	"3323.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15428"	"Splicing factor 3A subunit 2 OS=Homo sapiens OX=9606 GN=SF3A2 PE=1 SV=2"	"11"	"6"	"17"	"6"	"464"	"49.2"	"9.64"	"3471.75"	"29.86"	"6"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf12874, Pf16835"	"8175"	"ENSG00000104897"	"SF3A2"	"B2RBU1; D6W605; hsa:8175; O75245; Q15428"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"650.2"	"460.3"	"580.2"	"554.7"	"597.4"	"553.3"	"1309.2"	"1229.8"	"923.9"	"1420.8"	"1679.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P67870"	"Casein kinase II subunit beta OS=Homo sapiens OX=9606 GN=CSNK2B PE=1 SV=1"	"34"	"6"	"15"	"6"	"215"	"24.9"	"5.55"	"3352.76"	"29.62"	"6"	"6"	"cell-cell signaling;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;kinase activity;other molecular function"	"Pf01214"	"1460"	"ENSG00000204435; ENSG00000206406; ENSG00000224398; ENSG00000224774; ENSG00000228875; ENSG00000230700; ENSG00000232960"	"CSNK2B"	"B0UXA9; hsa:1460; P07312; P13862; P67870; Q4VX47"	"Alzheimer's disease and miRNA effects; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Measles virus infection; Pleural mesothelioma; Alzheimer's disease"	"Condensation of Prometaphase Chromosomes; Neutrophil degranulation; Regulation of PTEN stability and activity; KEAP1-NFE2L2 pathway; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Regulation of TP53 Activity through Phosphorylation; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; WNT mediated activation of DVL; Signal transduction by L1; Receptor Mediated Mitophagy; Synthesis of PC"	"19"	"0"	"239.8"	"159.3"	"221.6"	"243.2"	"222.9"	"252.8"	"1595.8"	"1608.8"	"1340.7"	"2237.4"	"2752.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92598"	"Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1"	"13"	"9"	"15"	"8"	"858"	"96.8"	"5.39"	"2051.79"	"29.54"	"6"	"9"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00012"	"10808"	"ENSG00000120694"	"HSPH1"	"B4DYH1; hsa:10808; O95739; Q5TBM6; Q5TBM7; Q5TBM8; Q92598; Q9UPC4"	""	"Regulation of HSF1-mediated heat shock response; Scavenging by Class F Receptors"	"2"	"0"	"354.2"	"213.5"	"337.4"	"318.8"	"295.9"	"344.3"	"469.7"	"415.0"	"300.3"	"512.3"	"773.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13642"	"Four and a half LIM domains protein 1 OS=Homo sapiens OX=9606 GN=FHL1 PE=1 SV=4"	"25"	"7"	"12"	"7"	"323"	"36.2"	"8.97"	"2016.38"	"29.50"	"4"	"6"	"other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00412"	"2273"	"ENSG00000022267"	"FHL1"	"B7Z5T4; B7Z793; hsa:2273; O95212; Q13230; Q13642; Q13645; Q5JXI7; Q5M7Y6; Q6IB30; Q9NZ40; Q9UKZ8; Q9Y630"	"Notch signaling pathway"	""	"1"	"0"	"731.4"	"507.8"	"784.1"	"623.2"	"746.6"	"769.0"	"1425.9"	"1400.7"	"1086.4"	"1537.6"	"2458.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12081"	"Histidine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=HARS1 PE=1 SV=2"	"21"	"10"	"20"	"10"	"509"	"57.4"	"5.88"	"3270.76"	"29.48"	"8"	"8"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00458, Pf03129, Pf13393"	"3035"	"ENSG00000170445"	"HARS1"	"B4DHQ1; B4DY73; D6REN6; hsa:3035; J3KNE5; P12081"	"Allograft rejection"	"Cytosolic tRNA aminoacylation"	"2"	"0"	"281.9"	"200.8"	"334.6"	"276.2"	"318.7"	"329.2"	"643.9"	"797.0"	"1083.8"	"2483.4"	"5073.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15046"	"Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3"	"13"	"8"	"17"	"8"	"597"	"68.0"	"6.35"	"2998.99"	"29.48"	"7"	"8"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00152, Pf01336"	"3735"	"ENSG00000065427"	"KARS1"	"A8MSK1; D3DUK4; hsa:3735; O14946; Q15046; Q96J25; Q9HB23"	""	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation; Mitochondrial tRNA aminoacylation"	"3"	"0"	"453.6"	"280.4"	"422.4"	"479.6"	"492.7"	"568.8"	"1661.4"	"1601.0"	"1088.8"	"1781.8"	"2445.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16629"	"Serine/arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1"	"30"	"7"	"17"	"7"	"238"	"27.4"	"11.82"	"1950.40"	"29.44"	"3"	"7"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6432"	"ENSG00000115875"	"SRSF7"	"B4DLU6; G5E9M3; hsa:6432; Q16629; Q564D3"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"7"	"0"	"736.1"	"504.2"	"635.7"	"549.9"	"625.6"	"713.1"	"1714.1"	"1687.8"	"1810.3"	"3964.6"	"5312.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UQ13"	"Leucine-rich repeat protein SHOC-2 OS=Homo sapiens OX=9606 GN=SHOC2 PE=1 SV=2"	"17"	"8"	"16"	"8"	"582"	"64.8"	"8.46"	"2099.56"	"29.36"	"6"	"8"	"signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf13855"	"8036"	"ENSG00000108061"	"SHOC2"	"A8K9W8; B3KR23; hsa:8036; O76063; Q5VZS8; Q5VZS9; Q9UQ13"	"Ras signaling; 22q11.2 copy number variation syndrome; Autophagy in pancreatic ductal adenocarcinoma"	"RAF activation; SHOC2 M1731 mutant abolishes MRAS complex function; Gain-of-function MRAS complexes activate RAF signaling"	"6"	"0"	"221.3"	"131.9"	"225.0"	"179.9"	"212.4"	"220.7"	"1225.9"	"1215.0"	"1135.0"	"2278.8"	"3944.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P84103"	"Serine/arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1"	"43"	"7"	"16"	"7"	"164"	"19.3"	"11.65"	"2404.45"	"29.24"	"5"	"7"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6428"	"ENSG00000112081"	"SRSF3"	"B4E241; hsa:6428; O08831; P23152; P84103; Q5R3K0"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"6"	"0"	"1796.2"	"1058.5"	"1240.9"	"1156.4"	"1231.1"	"1323.8"	"4167.6"	"3863.1"	"2956.9"	"3573.9"	"3605.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WUM0"	"Nuclear pore complex protein Nup133 OS=Homo sapiens OX=9606 GN=NUP133 PE=1 SV=2"	"11"	"10"	"17"	"10"	"1156"	"128.9"	"5.10"	"3172.91"	"28.96"	"9"	"8"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf03177"	"55746"	"ENSG00000069248"	"NUP133"	"B2RAZ8; hsa:55746; Q5T8N0; Q8WUM0; Q9H9W2; Q9NV71; Q9NVC4"	"Ciliary landscape"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; Separation of Sister Chromatids; snRNP Assembly; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; SUMOylation of DNA replication proteins; SARS-CoV-2 activates/modulates innate and adaptive immune responses; HCMV Early Events; SUMOylation of DNA damage response and repair proteins; Regulation of HSF1-mediated heat shock response; HCMV Late Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; Postmitotic nuclear pore complex (NPC) reformation"	"36"	"0"	"591.4"	"358.6"	"489.9"	"590.2"	"541.2"	"716.3"	"950.2"	"915.5"	"615.6"	"1101.2"	"1270.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05114"	"Non-histone chromosomal protein HMG-14 OS=Homo sapiens OX=9606 GN=HMGN1 PE=1 SV=3"	"56"	"7"	"16"	"7"	"100"	"10.7"	"9.60"	"3128.27"	"28.94"	"6"	"6"	"cell organization and biogenesis;DNA metabolism;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01101"	"3150"	"ENSG00000205581"	"HMGN1"	"hsa:3150; P05114; Q3KQR8"	"ATM signaling in development and disease ; p38 MAPK signaling pathway; Pleural mesothelioma; Nucleotide excision repair in xeroderma pigmentosum"	"Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	"8"	"0"	"814.8"	"388.7"	"562.8"	"476.0"	"585.2"	"562.8"	"2421.2"	"2084.8"	"1486.9"	"2892.2"	"5523.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96I25"	"Splicing factor 45 OS=Homo sapiens OX=9606 GN=RBM17 PE=1 SV=1"	"30"	"11"	"22"	"10"	"401"	"44.9"	"5.97"	"4344.84"	"28.88"	"10"	"9"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf01585"	"84991"	"ENSG00000134453"	"RBM17"	"hsa:84991; Q96GY6; Q96I25"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"1"	"884.8"	"428.5"	"506.5"	"531.2"	"535.0"	"570.6"	"1055.4"	"946.4"	"818.8"	"1086.8"	"1562.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q2TAY7"	"WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2"	"18"	"8"	"19"	"8"	"513"	"57.5"	"7.18"	"3726.19"	"28.79"	"8"	"8"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00400, Pf17814"	"55234"	"ENSG00000122692"	"SMU1"	"B4E3L0; hsa:55234; Q2TAY7; Q9BU59; Q9HA96; Q9NVD1"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"349.3"	"268.1"	"338.7"	"291.0"	"320.8"	"359.1"	"1422.3"	"1398.0"	"1202.4"	"1922.8"	"2025.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P36873"	"Serine/threonine-protein phosphatase PP1-gamma catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CC PE=1 SV=1"	"29"	"7"	"15"	"2"	"323"	"37.0"	"6.54"	"2739.01"	"28.76"	"6"	"7"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00149, Pf16891"	"5501"	"ENSG00000186298"	"PPP1CC"	"hsa:5501; P36873"	"Common pathways underlying drug addiction; Focal adhesion; Hippo-Merlin signaling dysregulation; Neuroinflammation and glutamatergic signaling"	"Separation of Sister Chromatids; Triglyceride catabolism; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Circadian Clock; RAF activation; SHOC2 M1731 mutant abolishes MRAS complex function; Gain-of-function MRAS complexes activate RAF signaling; Downregulation of TGF-beta receptor signaling"	"16"	"0"	"213.3"	"158.3"	"182.1"	"187.8"	"183.9"	"209.3"	"980.0"	"895.5"	"699.2"	"1055.3"	"1189.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P2J5"	"Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2"	"6"	"6"	"20"	"6"	"1176"	"134.4"	"7.30"	"2983.57"	"28.57"	"6"	"6"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00133, Pf08264"	"51520"	"ENSG00000133706"	"LARS1"	"A2RRR4; A7E266; B4DJ10; hsa:51520; Q2TU79; Q9NSE1; Q9P2J5"	""	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"2"	"0"	"450.5"	"272.9"	"421.9"	"499.6"	"439.9"	"571.9"	"611.0"	"586.6"	"404.9"	"627.8"	"796.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18754"	"Regulator of chromosome condensation OS=Homo sapiens OX=9606 GN=RCC1 PE=1 SV=1"	"20"	"7"	"17"	"7"	"421"	"44.9"	"7.52"	"3481.67"	"28.54"	"7"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00415"	"1104"	"ENSG00000180198"	"RCC1"	"hsa:1104; P18754; Q16269; Q6NT97"	"22q11.2 copy number variation syndrome"	"Rev-mediated nuclear export of HIV RNA; Nuclear import of Rev protein; Postmitotic nuclear pore complex (NPC) reformation"	"4"	"0"	"574.6"	"365.0"	"564.6"	"571.4"	"555.6"	"634.9"	"1885.3"	"1893.4"	"1393.2"	"1878.3"	"2493.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N1G4"	"Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1"	"16"	"7"	"15"	"7"	"583"	"63.4"	"8.28"	"2837.07"	"28.46"	"6"	"7"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	""	"other molecular function"	"Pf00560, Pf03483, Pf12799"	"57470"	"ENSG00000130764"	"LRRC47"	"hsa:57470; Q8N1G4; Q9ULN5"	""	""	"0"	"0"	"115.9"	"76.6"	"110.3"	"99.6"	"115.4"	"120.0"	"587.2"	"557.5"	"410.4"	"615.3"	"791.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQ61"	"Telomerase RNA component interacting RNase OS=Homo sapiens OX=9606 GN=TRIR PE=1 SV=1"	"28"	"5"	"8"	"5"	"176"	"18.4"	"9.44"	"756.49"	"28.45"	"2"	"4"	"RNA metabolism OR transcription;other metabolic processes"	""	"nucleic acid binding activity;other molecular function"	""	"79002"	"ENSG00000123144"	"TRIR"	"hsa:79002; Q9BQ61"	""	""	"0"	"0"	"559.1"	"263.8"	"433.2"	"529.5"	"449.7"	"604.0"	"1626.0"	"1400.7"	"816.6"	"1370.7"	"2167.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95819"	"Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens OX=9606 GN=MAP4K4 PE=1 SV=2"	"9"	"8"	"17"	"5"	"1239"	"142.0"	"7.46"	"2295.34"	"28.43"	"6"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other cell component"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00069, Pf00780"	"9448"	"ENSG00000071054"	"MAP4K4"	"E7ESS2; hsa:9448; O75172; O95819; Q9NST7"	"MAPK signaling pathway; Angiopoietin-like protein 8 regulatory pathway; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-YAP signaling; Insulin signaling; Pleural mesothelioma"	"Oxidative Stress Induced Senescence"	"7"	"3"	"194.9"	"123.4"	"183.4"	"180.2"	"209.3"	"210.7"	"680.6"	"1330.8"	"883.5"	"910.8"	"953.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q71DI3"	"Histone H3.2 OS=Homo sapiens OX=9606 GN=H3C15 PE=1 SV=3"	"54"	"7"	"15"	"1"	"136"	"15.4"	"11.27"	"2127.45"	"28.36"	"6"	"6"	"cell organization and biogenesis"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125"	"126961; 333932; 653604"	"ENSG00000183598; ENSG00000203811; ENSG00000203852"	"H3C13; H3C14; H3C15"	"A2BDF6; A6NFS4; hsa:126961; hsa:333932; hsa:653604; Q6B053; Q71DI3"	"Histone modifications; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma"	"Meiotic recombination; Amyloid fiber formation; HCMV Late Events; RUNX1 regulates transcription of genes involved in differentiation of HSCs; HCMV Early Events; Transcriptional regulation by small RNAs; B-WICH complex positively regulates rRNA expression; Formation of the beta-catenin:TCF transactivating complex; Oxidative Stress Induced Senescence; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Pre-NOTCH Transcription and Translation; Senescence-Associated Secretory Phenotype (SASP); RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; HATs acetylate histones; RNA Polymerase I Promoter Escape; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Condensation of Prophase Chromosomes; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis; RMTs methylate histone arginines; Interleukin-7 signaling; Factors involved in megakaryocyte development and platelet production; HDMs demethylate histones; PKMTs methylate histone lysines"	"36"	"0"	"5.1"	"0.0"	"2.8"	"5.0"	"5.4"	"5.2"	"21.0"	"24.4"	"16.5"	"25.1"	"27.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61158"	"Actin-related protein 3 OS=Homo sapiens OX=9606 GN=ACTR3 PE=1 SV=3"	"20"	"6"	"13"	"6"	"418"	"47.3"	"5.88"	"2422.99"	"28.33"	"5"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00022"	"10096"	"ENSG00000115091"	"ACTR3"	"hsa:10096; P32391; P61158; Q53QM2"	"Physico-chemical features and toxicity-associated pathways"	"EPHB-mediated forward signaling; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis"	"6"	"0"	"181.3"	"146.0"	"206.6"	"182.2"	"202.4"	"222.5"	"501.6"	"657.2"	"550.6"	"1102.7"	"2360.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95881"	"Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1"	"43"	"7"	"17"	"7"	"172"	"19.2"	"5.40"	"3552.97"	"28.29"	"6"	"5"	"other biological processes"	"ER/Golgi"	"other molecular function"	"Pf13899"	"51060"	"ENSG00000117862"	"TXNDC12"	"B3KQS0; hsa:51060; O95881; Q5T1T4; Q96H50"	""	""	"0"	"0"	"1608.7"	"986.5"	"1396.8"	"1648.3"	"1346.2"	"1630.1"	"2272.5"	"2120.7"	"1523.4"	"1845.7"	"1941.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P29692"	"Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5"	"34"	"11"	"21"	"8"	"281"	"31.1"	"5.01"	"4832.70"	"28.14"	"11"	"7"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00736, Pf10587"	"1936"	"ENSG00000104529; ENSG00000273594"	"EEF1D"	"B4DDU4; D3DWK3; E9PBQ9; hsa:1936; P29692; Q4VBZ6; Q969J1; Q96I38"	"Translation factors"	"Eukaryotic Translation Elongation"	"2"	"0"	"538.5"	"330.6"	"458.8"	"566.4"	"483.2"	"664.2"	"1144.3"	"1159.0"	"855.7"	"1258.1"	"1662.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63241"	"Eukaryotic translation initiation factor 5A-1 OS=Homo sapiens OX=9606 GN=EIF5A PE=1 SV=2"	"25"	"4"	"19"	"4"	"154"	"16.8"	"5.24"	"3643.92"	"28.10"	"4"	"4"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf01287"	"1984"	"ENSG00000132507; ENSG00000288145"	"EIF5A"	"A8K9A0; D3DTP2; hsa:1984; P10159; P63241; Q16182; Q7L7L3; Q7Z4L1; Q9D0G2"	"Translation factors; eIF5A regulation in response to inhibition of the nuclear export system"	"Hypusine synthesis from eIF5A-lysine"	"3"	"0"	"1775.1"	"786.6"	"1354.7"	"1189.8"	"1356.8"	"1340.5"	"2276.2"	"2033.3"	"1847.6"	"3727.2"	"8300.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05141"	"ADP/ATP translocase 2 OS=Homo sapiens OX=9606 GN=SLC25A5 PE=1 SV=7"	"26"	"8"	"21"	"2"	"298"	"32.8"	"9.69"	"3648.13"	"28.06"	"8"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;mitochondrion"	"transporter activity;other molecular function"	"Pf00153"	"292"	"ENSG00000005022"	"SLC25A5"	"B2RCV1; hsa:292; O43350; P05141"	"Electron transport chain: OXPHOS system in mitochondria; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane; Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization"	"5"	"6"	"1313.4"	"829.3"	"1067.9"	"821.9"	"1041.6"	"1073.1"	"1572.3"	"1398.3"	"1110.1"	"1840.8"	"2579.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKM9"	"RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1"	"28"	"9"	"20"	"9"	"306"	"32.4"	"9.17"	"4060.15"	"27.96"	"9"	"8"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00076"	"22913"	"ENSG00000125970"	"RALY"	"hsa:22913; Q14621; Q2M365; Q5QPL8; Q9BQX6; Q9UJE3; Q9UKM9"	""	""	"0"	"0"	"1837.7"	"1198.5"	"1574.7"	"1330.0"	"1523.7"	"1728.1"	"2649.6"	"2185.0"	"1383.2"	"2833.2"	"4457.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62424"	"60S ribosomal protein L7a OS=Homo sapiens OX=9606 GN=RPL7A PE=1 SV=2"	"30"	"9"	"18"	"9"	"266"	"30.0"	"10.61"	"3888.28"	"27.93"	"9"	"7"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01248"	"6130"	"ENSG00000148303; ENSG00000280858"	"RPL7A"	"hsa:6130; P11518; P62424; Q5T8U4"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; SRP-dependent cotranslational protein targeting to membrane; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"901.7"	"579.1"	"716.0"	"677.5"	"743.3"	"770.2"	"2988.2"	"2698.5"	"1823.6"	"3232.0"	"3869.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P43487"	"Ran-specific GTPase-activating protein OS=Homo sapiens OX=9606 GN=RANBP1 PE=1 SV=1"	"32"	"6"	"16"	"6"	"201"	"23.3"	"5.29"	"2183.77"	"27.93"	"5"	"6"	"transport;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00638"	"5902"	"ENSG00000099901"	"RANBP1"	"hsa:5902; P43487; Q53EY3"	"22q11.2 copy number variation syndrome"	"Rev-mediated nuclear export of HIV RNA"	"2"	"0"	"825.2"	"338.4"	"614.6"	"560.7"	"620.7"	"610.8"	"970.7"	"863.1"	"681.6"	"1104.7"	"1894.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14737"	"Programmed cell death protein 5 OS=Homo sapiens OX=9606 GN=PDCD5 PE=1 SV=3"	"54"	"7"	"19"	"7"	"125"	"14.3"	"6.04"	"3518.07"	"27.93"	"7"	"5"	"other biological processes"	"cytosol;nucleus"	"enzyme regulator activity;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf01984"	"9141"	"ENSG00000105185"	"PDCD5"	"B4DE64; hsa:9141; O14737; Q53YC9; Q6IB70"	""	""	"0"	"0"	"1660.6"	"850.7"	"1442.4"	"1103.1"	"1197.7"	"1256.3"	"2014.6"	"1757.6"	"1343.5"	"2034.6"	"3149.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82979"	"SAP domain-containing ribonucleoprotein OS=Homo sapiens OX=9606 GN=SARNP PE=1 SV=3"	"37"	"8"	"19"	"8"	"210"	"23.7"	"6.42"	"3081.77"	"27.57"	"7"	"8"	"other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02037"	"84324"	"ENSG00000205323"	"SARNP"	"A8K393; hsa:84324; P82979; Q9P066"	""	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"3"	"0"	"1332.7"	"763.7"	"1026.3"	"1142.0"	"1056.1"	"1165.5"	"2996.9"	"2758.1"	"2015.1"	"2929.3"	"4289.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23588"	"Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2"	"15"	"9"	"15"	"9"	"611"	"69.1"	"5.73"	"2803.20"	"27.47"	"7"	"7"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus"	"nucleic acid binding activity"	"Pf00076"	"1975"	"ENSG00000063046"	"EIF4B"	"B4DS13; hsa:1975; P23588; Q4G0E3; Q53HQ2; Q6GPH5; Q6IB46; Q8WYK5"	"Translation factors; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Translation inhibitors in chronically activated PDGFRA cells; Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins; Pleural mesothelioma; Interferon type I signaling pathways"	"Deadenylation of mRNA; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; mTORC1-mediated signalling"	"14"	"0"	"1178.5"	"606.3"	"924.7"	"840.2"	"891.2"	"928.5"	"1895.8"	"1690.5"	"1245.8"	"1809.7"	"2659.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50395"	"Rab GDP dissociation inhibitor beta OS=Homo sapiens OX=9606 GN=GDI2 PE=1 SV=2"	"14"	"5"	"15"	"2"	"445"	"50.6"	"6.47"	"2792.82"	"27.16"	"4"	"5"	"transport;signal transduction;other biological processes"	"non-structural extracellular;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00996"	"2665"	"ENSG00000057608"	"GDI2"	"hsa:2665; O43928; P50395; Q5SX88; Q9UQM6"	""	"Neutrophil degranulation; RAB GEFs exchange GTP for GDP on RABs"	"2"	"2"	"361.9"	"227.0"	"343.4"	"260.3"	"314.6"	"342.0"	"424.7"	"432.7"	"334.1"	"587.1"	"900.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05388"	"60S acidic ribosomal protein P0 OS=Homo sapiens OX=9606 GN=RPLP0 PE=1 SV=1"	"28"	"7"	"14"	"7"	"317"	"34.3"	"5.97"	"2849.19"	"27.12"	"7"	"7"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00428, Pf00466, Pf17777"	"6175"	"ENSG00000089157"	"RPLP0"	"hsa:6175; P05388; Q3B7A4; Q9BVK4"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"380.8"	"256.1"	"390.8"	"280.2"	"386.4"	"322.8"	"933.6"	"861.3"	"584.0"	"1062.6"	"1313.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NZI8"	"Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2"	"14"	"7"	"15"	"6"	"577"	"63.4"	"9.20"	"3123.68"	"27.03"	"7"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf00076"	"10642"	"ENSG00000159217"	"IGF2BP1"	"C9JT33; hsa:10642; Q9NZI8"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; eIF5A regulation in response to inhibition of the nuclear export system"	"MAPK6/MAPK4 signaling; Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"	"4"	"1"	"1007.7"	"576.8"	"905.1"	"681.7"	"866.0"	"871.9"	"1670.8"	"1462.3"	"1066.7"	"1819.0"	"2529.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P10599"	"Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3"	"54"	"5"	"15"	"5"	"105"	"11.7"	"4.92"	"2538.14"	"27.03"	"4"	"5"	"other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00085"	"7295"	"ENSG00000136810"	"TXN"	"B1ALW1; hsa:7295; O60744; P10599; Q53X69; Q96KI3; Q9UDG5"	"Selenium micronutrient network; Folic acid network; Selenium micronutrient network ; Folic acid network; Selenium micronutrient network; TNF-alpha signaling pathway; Complement system; Nuclear receptors meta-pathway; NRF2 pathway; VEGFA-VEGFR2 signaling; TAR syndrome"	"Detoxification of Reactive Oxygen Species; Oxidative Stress Induced Senescence; TP53 Regulates Metabolic Genes; Interconversion of nucleotide di- and triphosphates; The NLRP3 inflammasome; Purinergic signaling in leishmaniasis infection; Regulation of FOXO transcriptional activity by acetylation; Protein repair"	"19"	"0"	"841.2"	"662.4"	"778.8"	"620.1"	"685.2"	"800.0"	"1034.5"	"957.0"	"881.1"	"1309.4"	"1852.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14554"	"Protein disulfide-isomerase A5 OS=Homo sapiens OX=9606 GN=PDIA5 PE=1 SV=1"	"14"	"6"	"12"	"6"	"519"	"59.6"	"7.91"	"1594.06"	"27.03"	"2"	"6"	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00085"	"10954"	"ENSG00000065485"	"PDIA5"	"D3DN95; hsa:10954; Q14554; Q9BV43"	""	"XBP1(S) activates chaperone genes"	"1"	"0"	"119.0"	"81.9"	"116.7"	"124.5"	"127.8"	"118.4"	"438.3"	"619.7"	"800.3"	"1843.7"	"2565.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P54886"	"Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2"	"10"	"7"	"17"	"7"	"795"	"87.2"	"7.12"	"3040.82"	"27.02"	"7"	"7"	"other metabolic processes"	"other membranes;mitochondrion"	"kinase activity;other molecular function"	"Pf00171, Pf00696"	"5832"	"ENSG00000059573"	"ALDH18A1"	"B2R5Q4; B7Z350; B7Z5X8; B7ZLP1; D3DR44; hsa:5832; O95952; P54886; Q3KQU2; Q5T566; Q5T567; Q9UM72"	"Amino acid metabolism"	""	"1"	"0"	"475.4"	"292.5"	"366.1"	"453.9"	"458.2"	"524.7"	"1008.2"	"983.0"	"733.4"	"1063.5"	"1268.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35268"	"60S ribosomal protein L22 OS=Homo sapiens OX=9606 GN=RPL22 PE=1 SV=2"	"52"	"5"	"10"	"5"	"128"	"14.8"	"9.19"	"1445.02"	"27.02"	"4"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01776"	"6146"	"ENSG00000116251"	"RPL22"	"B2R495; hsa:6146; P35268; Q6IBD1"	"Cytoplasmic ribosomal proteins"	"SRP-dependent cotranslational protein targeting to membrane; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"95.7"	"59.4"	"83.5"	"88.0"	"94.2"	"107.2"	"593.1"	"593.4"	"504.2"	"887.4"	"1132.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50570"	"Dynamin-2 OS=Homo sapiens OX=9606 GN=DNM2 PE=1 SV=2"	"12"	"9"	"18"	"9"	"870"	"98.0"	"7.44"	"3329.66"	"27.02"	"8"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00169, Pf00350, Pf01031, Pf02212"	"1785"	"ENSG00000079805"	"DNM2"	"A8K1B6; E7EV30; E9PEQ4; hsa:1785; K7ESI9; P50570; Q5I0Y0; Q7Z5S3; Q9UPH4"	"Synaptic vesicle pathway; Fragile X syndrome; Intracellular trafficking proteins involved in CMT neuropathy"	"Clathrin-mediated endocytosis; MHC class II antigen presentation; Recycling pathway of L1; Lysosome Vesicle Biogenesis; NGF-stimulated transcription; Golgi Associated Vesicle Biogenesis; Toll Like Receptor 4 (TLR4) Cascade; NOSTRIN mediated eNOS trafficking; Retrograde neurotrophin signalling; Formation of annular gap junctions"	"14"	"0"	"359.1"	"231.6"	"445.5"	"324.9"	"379.8"	"370.5"	"1037.4"	"1632.9"	"1221.7"	"1521.0"	"1971.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14314"	"Glucosidase 2 subunit beta OS=Homo sapiens OX=9606 GN=PRKCSH PE=1 SV=2"	"18"	"10"	"16"	"9"	"528"	"59.4"	"4.41"	"2708.38"	"26.91"	"8"	"8"	"protein metabolism;other metabolic processes;developmental processes;signal transduction"	"ER/Golgi;other cell component"	"other molecular function"	"Pf12999, Pf13015, Pf13202"	"5589"	"ENSG00000130175"	"PRKCSH"	"A8K318; hsa:5589; P14314; Q96BU9; Q96D06; Q9P0W9"	""	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Advanced glycosylation endproduct receptor signaling; Maturation of spike protein; Calnexin/calreticulin cycle; Maturation of spike protein"	"7"	"1"	"1372.2"	"843.2"	"1344.7"	"1365.2"	"1154.0"	"1494.3"	"2511.5"	"2189.2"	"1571.4"	"2346.0"	"3307.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P39687"	"Acidic leucine-rich nuclear phosphoprotein 32 family member A OS=Homo sapiens OX=9606 GN=ANP32A PE=1 SV=1"	"23"	"6"	"15"	"4"	"249"	"28.6"	"4.09"	"2396.91"	"26.90"	"5"	"5"	"transport;signal transduction;other biological processes"	"ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf14580"	"8125"	"ENSG00000140350"	"ANP32A"	"B2R6T4; hsa:8125; P39687; Q53FK4; Q5J8L8; Q7M4N6"	"IL-18 signaling pathway"	"HuR (ELAVL1) binds and stabilizes mRNA"	"2"	"0"	"772.8"	"434.9"	"633.2"	"493.0"	"568.5"	"584.4"	"1776.0"	"1639.6"	"1092.2"	"1620.6"	"2800.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60216"	"Double-strand-break repair protein rad21 homolog OS=Homo sapiens OX=9606 GN=RAD21 PE=1 SV=2"	"16"	"7"	"12"	"7"	"631"	"71.6"	"4.65"	"2656.58"	"26.77"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04824, Pf04825"	"5885"	"ENSG00000164754"	"RAD21"	"A8K0E0; hsa:5885; O60216; Q15001; Q99568"	"Cell cycle; Prion disease pathway; Regulation of sister chromatid separation at the metaphase-anaphase transition; Cohesin complex - Cornelia de Lange syndrome; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; 10q22q23 copy number variation"	"Meiotic synapsis; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; SUMOylation of DNA damage response and repair proteins; Estrogen-dependent gene expression; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"13"	"0"	"433.2"	"286.8"	"405.9"	"391.4"	"390.6"	"489.8"	"1134.9"	"1056.3"	"734.3"	"1242.6"	"1605.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53582"	"Methionine aminopeptidase 1 OS=Homo sapiens OX=9606 GN=METAP1 PE=1 SV=2"	"28"	"8"	"11"	"8"	"386"	"43.2"	"7.17"	"1620.13"	"26.76"	"4"	"7"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00557, Pf15801"	"23173"	"ENSG00000164024"	"METAP1"	"B4E2E6; hsa:23173; P53582"	""	"Inactivation, recovery and regulation of the phototransduction cascade"	"1"	"0"	"361.9"	"230.1"	"321.4"	"415.3"	"386.8"	"464.9"	"1107.4"	"1146.6"	"1029.6"	"1678.7"	"2670.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H0D6"	"5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1"	"9"	"8"	"17"	"8"	"950"	"108.5"	"7.47"	"3369.64"	"26.75"	"8"	"7"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03159, Pf17846"	"22803"	"ENSG00000088930"	"XRN2"	"hsa:22803; Q3L8N4; Q6KGZ9; Q9BQL1; Q9H0D6; Q9NTW0; Q9NXS6; Q9UL53"	"mRNA processing"	"Major pathway of rRNA processing in the nucleolus and cytosol; Association of TriC/CCT with target proteins during biosynthesis"	"3"	"0"	"634.2"	"394.8"	"592.5"	"550.6"	"581.2"	"649.6"	"1291.3"	"1214.1"	"872.0"	"1205.6"	"1612.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BUJ2"	"Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2"	"11"	"11"	"20"	"10"	"856"	"95.7"	"6.92"	"3282.75"	"26.69"	"10"	"9"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00622, Pf02037, Pf13671"	"11100"	"ENSG00000105323"	"HNRNPUL1"	"B3KMW7; hsa:11100; O76022; Q6ZSZ0; Q7L8P4; Q8N6Z4; Q96G37; Q9BUJ2; Q9HAL3; Q9UG75"	""	""	"0"	"0"	"734.2"	"415.5"	"653.6"	"552.2"	"599.3"	"627.2"	"1120.1"	"996.7"	"698.8"	"1160.2"	"1738.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46777"	"60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3"	"22"	"6"	"16"	"6"	"297"	"34.3"	"9.72"	"3312.72"	"26.67"	"6"	"6"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf14204, Pf17144"	"6125"	"ENSG00000122406"	"RPL5"	"hsa:6125; P46777; Q32LZ3; Q53HH6; Q9H3F4"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"850.2"	"561.5"	"684.0"	"607.8"	"689.3"	"669.2"	"2871.1"	"2613.1"	"1757.4"	"2554.1"	"2906.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60716"	"Catenin delta-1 OS=Homo sapiens OX=9606 GN=CTNND1 PE=1 SV=1"	"9"	"9"	"18"	"9"	"968"	"108.1"	"6.23"	"3800.49"	"26.58"	"9"	"7"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00514"	"1500"	"ENSG00000198561"	"CTNND1"	"A8K939; hsa:1500; O15088; O60713; O60714; O60715; O60716; O60935; Q6DHZ7; Q6RBX8; Q9UP71; Q9UP72; Q9UP73"	"VEGFA-VEGFR2 signaling; Wnt signaling pathway and pluripotency"	"VEGFR2 mediated vascular permeability; Adherens junctions interactions; InlA-mediated entry of Listeria monocytogenes into host cells; Regulation of CDH11 function; Regulation of CDH19 Expression and Function; CDH11 homotypic and heterotypic interactions"	"8"	"0"	"826.7"	"542.1"	"672.8"	"695.4"	"703.4"	"859.1"	"1660.8"	"1695.5"	"1199.9"	"1659.6"	"1893.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35579"	"Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4"	"5"	"8"	"14"	"5"	"1960"	"226.4"	"5.60"	"2365.75"	"26.50"	"6"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00063, Pf01576, Pf02736"	"4627"	"ENSG00000100345"	"MYH9"	"A8K6E4; hsa:4627; O60805; P35579; Q60FE2; Q86T83"	"Primary focal segmental glomerulosclerosis (FSGS); VEGFA-VEGFR2 signaling; Nephrotic syndrome"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Signaling by ALK fusions and activated point mutants; RHO GTPases activate CIT; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; RHO GTPases activate PAKs; CD163 mediating an anti-inflammatory response"	"16"	"0"	"53.1"	"39.0"	"69.1"	"73.1"	"86.8"	"78.2"	"294.2"	"232.1"	"162.9"	"308.0"	"407.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13347"	"Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1"	"24"	"8"	"15"	"8"	"325"	"36.5"	"5.64"	"2522.42"	"26.48"	"7"	"8"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf00400"	"8668"	"ENSG00000084623"	"EIF3I"	"hsa:8668; Q13347"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition"	"8"	"0"	"964.8"	"669.0"	"880.7"	"701.8"	"830.2"	"766.2"	"1798.1"	"1620.8"	"1183.8"	"1793.8"	"2268.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13185"	"Chromobox protein homolog 3 OS=Homo sapiens OX=9606 GN=CBX3 PE=1 SV=4"	"39"	"6"	"16"	"4"	"183"	"20.8"	"5.33"	"3985.31"	"26.36"	"6"	"5"	"cell organization and biogenesis;stress response;other biological processes"	"other membranes;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00385, Pf01393"	"11335"	"ENSG00000122565"	"CBX3"	"hsa:11335; Q13185; Q96CD7; Q99409; Q9BVS3; Q9P0Z6"	"Exercise-induced circadian regulation; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; NIPBL role in DNA damage - Cornelia de Lange syndrome"	"RNA Polymerase I Promoter Escape; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Transcriptional Regulation by E2F6"	"6"	"3"	"1105.6"	"568.7"	"860.8"	"803.8"	"821.1"	"930.9"	"1504.7"	"1332.7"	"938.3"	"1539.3"	"2466.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96NC0"	"Zinc finger matrin-type protein 2 OS=Homo sapiens OX=9606 GN=ZMAT2 PE=1 SV=1"	"33"	"8"	"19"	"8"	"199"	"23.6"	"9.01"	"2863.64"	"26.36"	"6"	"6"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf12171"	"153527"	"ENSG00000146007"	"ZMAT2"	"hsa:153527; Q96NC0"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"900.7"	"436.3"	"614.2"	"759.8"	"611.2"	"877.6"	"4851.8"	"4594.0"	"2992.3"	"4382.8"	"5605.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15424"	"Scaffold attachment factor B1 OS=Homo sapiens OX=9606 GN=SAFB PE=1 SV=4"	"7"	"7"	"18"	"7"	"915"	"102.6"	"5.47"	"3318.63"	"26.36"	"7"	"7"	"cell organization and biogenesis;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf02037"	"6294"	"ENSG00000160633"	"SAFB"	"A0AV56; B7Z5B6; B7ZLP6; F5H0H3; hsa:6294; O60406; Q15424; Q59HH8"	"Interleukin-1 (IL-1) structural pathway"	"SUMOylation of transcription cofactors"	"2"	"0"	"1301.1"	"738.1"	"955.4"	"799.5"	"1029.8"	"1045.4"	"1994.1"	"1463.3"	"1051.2"	"2167.0"	"2752.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6UX04"	"Spliceosome-associated protein CWC27 homolog OS=Homo sapiens OX=9606 GN=CWC27 PE=1 SV=1"	"10"	"5"	"11"	"5"	"472"	"53.8"	"5.80"	"2533.09"	"26.26"	"4"	"5"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf00160"	"10283"	"ENSG00000153015"	"CWC27"	"hsa:10283; O60529; O60530; Q6UX04; Q96EM3"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"298.6"	"190.3"	"244.9"	"250.0"	"297.6"	"300.4"	"747.5"	"747.6"	"516.4"	"835.8"	"1291.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16775"	"Hydroxyacylglutathione hydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=HAGH PE=1 SV=2"	"28"	"6"	"12"	"6"	"308"	"33.8"	"8.12"	"1663.01"	"26.20"	"4"	"5"	"other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00753, Pf16123"	"3029"	"ENSG00000063854"	"HAGH"	"A8K290; B4DP33; B4DRA7; E7EN93; hsa:3029; Q16775"	""	""	"0"	"0"	"397.3"	"171.0"	"248.5"	"252.9"	"230.4"	"285.1"	"402.1"	"354.6"	"285.9"	"430.2"	"735.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P68431"	"Histone H3.1 OS=Homo sapiens OX=9606 GN=H3C1 PE=1 SV=2"	"54"	"7"	"15"	"1"	"136"	"15.4"	"11.12"	"2127.45"	"26.10"	"6"	"6"	"cell organization and biogenesis;other metabolic processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125"	"8350; 8351; 8352; 8353; 8354; 8355; 8356; 8357; 8358; 8968"	"ENSG00000197153; ENSG00000197409; ENSG00000273983; ENSG00000274750; ENSG00000275379; ENSG00000275714; ENSG00000277775; ENSG00000278828; ENSG00000286522; ENSG00000287080"	"H3C1; H3C10; H3C11; H3C12; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8"	"A0PJT7; A5PLR1; hsa:8350; hsa:8351; hsa:8352; hsa:8353; hsa:8354; hsa:8355; hsa:8356; hsa:8357; hsa:8358; hsa:8968; P02295; P02296; P16106; P68431; Q6ISV8; Q6NWP8; Q6NWP9; Q6NXU4; Q71DJ3; Q93081"	"Histone modifications; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma"	"Transcriptional regulation by small RNAs; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; HDACs deacetylate histones; Factors involved in megakaryocyte development and platelet production; HDMs demethylate histones; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Oxidative Stress Induced Senescence; Pre-NOTCH Transcription and Translation; Amyloid fiber formation; HCMV Late Events; RUNX1 regulates transcription of genes involved in differentiation of HSCs; HCMV Early Events; B-WICH complex positively regulates rRNA expression; Formation of the beta-catenin:TCF transactivating complex; NoRC negatively regulates rRNA expression; Senescence-Associated Secretory Phenotype (SASP); RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; HATs acetylate histones; RNA Polymerase I Promoter Escape; Meiotic recombination; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Defective pyroptosis; Condensation of Prophase Chromosomes; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis; Interleukin-7 signaling; RMTs methylate histone arginines; PKMTs methylate histone lysines"	"36"	"7"	"1181.1"	"790.4"	"929.9"	"832.4"	"931.5"	"1037.5"	"2863.6"	"2722.8"	"1981.3"	"3231.5"	"4211.2"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62314"	"Small nuclear ribonucleoprotein Sm D1 OS=Homo sapiens OX=9606 GN=SNRPD1 PE=1 SV=1"	"37"	"3"	"14"	"3"	"119"	"13.3"	"11.56"	"2923.41"	"26.05"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01423"	"6632"	"ENSG00000167088"	"SNRPD1"	"B5BTZ1; hsa:6632; P13641; P62314"	"mRNA processing"	"mRNA Splicing - Major Pathway; SARS-CoV-2 modulates host translation machinery; snRNP Assembly; mRNA Splicing - Minor Pathway"	"5"	"0"	"313.1"	"235.0"	"330.4"	"265.4"	"288.7"	"300.1"	"594.2"	"623.2"	"545.1"	"790.7"	"1096.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18621"	"60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3"	"31"	"7"	"18"	"7"	"184"	"21.4"	"10.17"	"3082.87"	"25.90"	"7"	"7"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf00237"	"6139"	"ENSG00000265681"	"RPL17"	"B2R4H3; B4E3C2; B5ME31; hsa:6139; J3QL51; P18621; Q3KQW2; Q6NZ54; Q7M4M5"	"Cytoplasmic ribosomal proteins"	"SRP-dependent cotranslational protein targeting to membrane; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"965.4"	"551.9"	"762.7"	"685.8"	"777.7"	"826.0"	"3324.5"	"2845.9"	"1659.2"	"2965.8"	"3636.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43172"	"U4/U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2"	"20"	"9"	"15"	"9"	"522"	"58.4"	"7.42"	"2655.62"	"25.87"	"7"	"8"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00400, Pf08799"	"9128"	"ENSG00000136875"	"PRPF4"	"hsa:9128; O43172; O43445; O43864; Q5T1M8; Q96DG2; Q96IK4"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"411.9"	"252.9"	"347.6"	"310.1"	"351.8"	"350.6"	"776.7"	"735.0"	"535.3"	"877.2"	"1261.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NVZ3"	"Adaptin ear-binding coat-associated protein 2 OS=Homo sapiens OX=9606 GN=NECAP2 PE=1 SV=1"	"29"	"5"	"11"	"5"	"263"	"28.3"	"8.38"	"1911.33"	"25.84"	"4"	"5"	"transport"	"plasma membrane;other membranes"	""	"Pf07933"	"55707"	"ENSG00000157191"	"NECAP2"	"B4DY19; E9PGQ8; hsa:55707; Q5VSU4; Q5VSU5; Q9H7L1; Q9H8L1; Q9NVZ3"	""	"Cargo recognition for clathrin-mediated endocytosis"	"2"	"0"	"81.0"	"53.2"	"89.8"	"86.8"	"86.2"	"90.7"	"204.0"	"364.6"	"573.2"	"1047.1"	"1530.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46776"	"60S ribosomal protein L27a OS=Homo sapiens OX=9606 GN=RPL27A PE=1 SV=2"	"34"	"7"	"18"	"7"	"148"	"16.6"	"11.00"	"3456.76"	"25.75"	"7"	"5"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;other cell component"	"other molecular function"	"Pf00828"	"6157"	"ENSG00000166441"	"RPL27A"	"B2R4B3; hsa:6157; P46776"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"490.5"	"372.7"	"455.6"	"434.9"	"487.2"	"512.0"	"1674.7"	"1576.2"	"1093.5"	"1843.2"	"2090.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75400"	"Pre-mRNA-processing factor 40 homolog A OS=Homo sapiens OX=9606 GN=PRPF40A PE=1 SV=2"	"10"	"10"	"18"	"10"	"957"	"108.7"	"7.56"	"3143.28"	"25.73"	"8"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf00397, Pf01846"	"55660"	"ENSG00000196504"	"PRPF40A"	"hsa:55660; O43856; O75400; O75404; Q8TBQ1; Q9H782; Q9NWU9; Q9P0Q2; Q9Y5A8"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"819.0"	"465.4"	"732.0"	"628.0"	"792.1"	"706.2"	"1379.5"	"1289.8"	"930.4"	"1717.5"	"2244.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9ULV4"	"Coronin-1C OS=Homo sapiens OX=9606 GN=CORO1C PE=1 SV=1"	"23"	"12"	"21"	"12"	"474"	"53.2"	"7.08"	"4521.98"	"25.72"	"12"	"6"	"cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf08953, Pf16300"	"23603"	"ENSG00000110880"	"CORO1C"	"A7MAP0; A7MAP1; B3KU12; hsa:23603; Q9NSK5; Q9ULV4"	""	""	"0"	"0"	"933.3"	"534.2"	"817.3"	"817.8"	"846.8"	"823.2"	"3371.5"	"3183.1"	"2316.9"	"3902.5"	"4491.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99497"	"Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2"	"48"	"8"	"16"	"8"	"189"	"19.9"	"6.79"	"2658.52"	"25.68"	"6"	"7"	"cell-cell signaling;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf01965"	"11315"	"ENSG00000116288"	"PARK7"	"B2R4Z1; hsa:11315; O14805; Q6DR95; Q7LFU2; Q99497"	"Androgen receptor signaling pathway; Synaptic vesicle pathway; Parkinson's disease pathway"	"Aggrephagy; Late endosomal microautophagy; SUMOylation of transcription cofactors; Chaperone Mediated Autophagy"	"7"	"0"	"1917.2"	"1158.3"	"1664.1"	"1474.6"	"1722.8"	"1880.4"	"2267.1"	"1878.4"	"1173.6"	"1784.4"	"2571.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14625"	"Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1"	"15"	"11"	"16"	"11"	"803"	"92.4"	"4.84"	"2594.98"	"25.57"	"8"	"8"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00183, Pf02518"	"7184"	"ENSG00000166598"	"HSP90B1"	"hsa:7184; P14625; Q96A97"	"Photodynamic therapy-induced unfolded protein response; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Prion disease pathway; PI3K-Akt signaling pathway; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Interleukin-4 and Interleukin-13 signaling; Trafficking and processing of endosomal TLR; Scavenging by Class A Receptors; ATF6 (ATF6-alpha) activates chaperone genes"	"11"	"0"	"1240.2"	"706.6"	"994.6"	"940.9"	"1008.6"	"1247.8"	"1583.5"	"1422.0"	"1040.5"	"1782.9"	"2492.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13151"	"Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1"	"11"	"5"	"24"	"3"	"305"	"30.8"	"9.29"	"4514.50"	"25.55"	"5"	"4"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"10949"	"ENSG00000177733"	"HNRNPA0"	"hsa:10949; Q13151; Q6IB18"	""	""	"0"	"0"	"1540.1"	"775.2"	"1086.9"	"906.5"	"1035.4"	"1067.8"	"2669.5"	"2322.5"	"1645.6"	"2563.1"	"3507.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43175"	"D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4"	"11"	"5"	"16"	"5"	"533"	"56.6"	"6.71"	"3003.07"	"25.52"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;developmental processes;other biological processes"	"cytosol"	"other molecular function"	"Pf00389, Pf02826, Pf19304"	"26227"	"ENSG00000092621"	"PHGDH"	"B2RD08; hsa:26227; O43175; Q5SZU3; Q9BQ01"	"Trans-sulfuration, one-carbon metabolism and related pathways; Clear cell renal cell carcinoma pathways; Neuroinflammation and glutamatergic signaling; Amino acid metabolism in triple-negative breast cancer cells"	"Serine biosynthesis"	"5"	"0"	"464.2"	"301.5"	"429.6"	"371.4"	"399.1"	"436.2"	"522.8"	"449.1"	"336.1"	"597.5"	"777.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62495"	"Eukaryotic peptide chain release factor subunit 1 OS=Homo sapiens OX=9606 GN=ETF1 PE=1 SV=3"	"26"	"8"	"15"	"8"	"437"	"49.0"	"5.71"	"2440.50"	"25.49"	"6"	"7"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"enzyme regulator activity;translation activity;nucleic acid binding activity;other molecular function"	"Pf03463, Pf03464, Pf03465"	"2107"	"ENSG00000120705"	"ETF1"	"B2R6B4; D3DQC1; hsa:2107; P46055; P62495; Q5M7Z7; Q96CG1"	"Translation factors"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"5"	"0"	"221.5"	"128.8"	"214.3"	"226.9"	"237.6"	"246.7"	"582.7"	"564.9"	"462.4"	"685.9"	"1002.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60869"	"Endothelial differentiation-related factor 1 OS=Homo sapiens OX=9606 GN=EDF1 PE=1 SV=1"	"44"	"8"	"19"	"8"	"148"	"16.4"	"9.95"	"4114.98"	"25.38"	"8"	"5"	"other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01381, Pf08523"	"8721"	"ENSG00000107223"	"EDF1"	"hsa:8721; O60869; Q5T5T2; Q9UIM1"	""	""	"0"	"0"	"529.8"	"287.8"	"492.1"	"406.5"	"531.3"	"480.0"	"5237.3"	"4544.8"	"3523.3"	"5093.3"	"6693.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06753"	"Tropomyosin alpha-3 chain OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=2"	"24"	"8"	"20"	"8"	"285"	"32.9"	"4.72"	"3643.69"	"25.34"	"8"	"7"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	"cytoskeletal activity"	"Pf00261"	"7170"	"ENSG00000143549"	"TPM3"	"D3DV71; hsa:7170; P06753; P12324; Q2QD06; Q5VU58; Q5VU63; Q5VU66; Q5VU71; Q5VU72; Q8TCG3; Q969Q2; Q9NQH8"	"Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4); Striated muscle contraction pathway; VEGFA-VEGFR2 signaling"	"Signaling by ALK fusions and activated point mutants; RHOV GTPase cycle; Smooth Muscle Contraction; Striated Muscle Contraction"	"7"	"0"	"2354.9"	"997.7"	"1580.2"	"1730.8"	"1464.9"	"1700.0"	"2740.8"	"2560.7"	"1839.5"	"2593.6"	"3653.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P83731"	"60S ribosomal protein L24 OS=Homo sapiens OX=9606 GN=RPL24 PE=1 SV=1"	"36"	"7"	"17"	"7"	"157"	"17.8"	"11.25"	"3117.40"	"25.32"	"7"	"6"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01246"	"6152"	"ENSG00000114391"	"RPL24"	"B2R4Y3; hsa:6152; P38663; P83731; Q6IBS3"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"983.2"	"669.2"	"846.9"	"756.5"	"802.8"	"841.8"	"2883.1"	"2646.1"	"1770.7"	"2883.4"	"3344.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62280"	"40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3"	"38"	"7"	"16"	"7"	"158"	"18.4"	"10.30"	"3000.41"	"25.15"	"7"	"7"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00366, Pf16205"	"6205"	"ENSG00000142534"	"RPS11"	"B2R4F5; hsa:6205; P04643; P62280; Q498Y6; Q6IRY0"	"VEGFA-VEGFR2 signaling; IL-18 signaling pathway; Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"21"	"0"	"1409.7"	"906.2"	"1460.0"	"1094.8"	"1127.6"	"1132.3"	"3106.9"	"2597.9"	"1707.4"	"2953.5"	"4568.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NFH3"	"Nucleoporin Nup43 OS=Homo sapiens OX=9606 GN=NUP43 PE=1 SV=1"	"14"	"5"	"13"	"5"	"380"	"42.1"	"5.63"	"2640.48"	"25.13"	"4"	"5"	"cell cycle OR cell proliferation;transport;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00400"	"348995"	"ENSG00000120253"	"NUP43"	"B4E2F0; hsa:348995; Q8NFH3; Q9H8S0"	""	"Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Regulation of HSF1-mediated heat shock response; ISG15 antiviral mechanism; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Vpr-mediated nuclear import of PICs; SUMOylation of DNA damage response and repair proteins; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transport of Mature mRNA derived from an Intron-Containing Transcript; tRNA processing in the nucleus; HCMV Late Events; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; HCMV Early Events; EML4 and NUDC in mitotic spindle formation; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; snRNP Assembly; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); SARS-CoV-2 activates/modulates innate and adaptive immune responses; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Postmitotic nuclear pore complex (NPC) reformation"	"35"	"0"	"243.8"	"163.2"	"214.1"	"253.7"	"227.3"	"227.8"	"428.1"	"430.4"	"307.4"	"461.9"	"595.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P57740"	"Nuclear pore complex protein Nup107 OS=Homo sapiens OX=9606 GN=NUP107 PE=1 SV=1"	"11"	"9"	"15"	"9"	"925"	"106.3"	"5.43"	"2250.92"	"25.11"	"7"	"7"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes"	"other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf04121"	"57122"	"ENSG00000111581"	"NUP107"	"B4DZ67; hsa:57122; P57740; Q6PJE1"	"Gastric cancer network 1; Primary ovarian insufficiency"	"Transport of Mature mRNA Derived from an Intronless Transcript; tRNA processing in the nucleus; SUMOylation of RNA binding proteins; Regulation of HSF1-mediated heat shock response; HCMV Late Events; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; HCMV Early Events; EML4 and NUDC in mitotic spindle formation; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); SARS-CoV-2 activates/modulates innate and adaptive immune responses; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Postmitotic nuclear pore complex (NPC) reformation"	"37"	"0"	"619.2"	"396.9"	"560.4"	"602.6"	"577.3"	"781.4"	"1009.6"	"931.2"	"692.0"	"960.9"	"1273.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25786"	"Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1"	"27"	"5"	"11"	"5"	"263"	"29.5"	"6.61"	"2023.29"	"25.11"	"4"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00227, Pf10584"	"5682"	"ENSG00000129084"	"PSMA1"	"A8K400; hsa:5682; P25786; Q53YE8; Q9BRV9"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"ER-Phagosome pathway; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"62"	"0"	"488.2"	"290.5"	"546.7"	"482.7"	"548.2"	"500.4"	"1212.6"	"1185.1"	"883.3"	"1339.9"	"2020.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92738"	"USP6 N-terminal-like protein OS=Homo sapiens OX=9606 GN=USP6NL PE=1 SV=3"	"11"	"8"	"14"	"8"	"828"	"94.0"	"9.07"	"2657.02"	"25.09"	"7"	"7"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00566"	"9712"	"ENSG00000148429"	"USP6NL"	"A8KA79; hsa:9712; Q15400; Q5VV10; Q7L0K9; Q92738"	"EGF/EGFR signaling pathway"	"Retrograde transport at the Trans-Golgi-Network"	"2"	"0"	"133.8"	"105.2"	"155.1"	"130.8"	"146.3"	"172.9"	"912.4"	"1628.7"	"1832.3"	"2716.4"	"3036.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P98175"	"RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3"	"10"	"9"	"16"	"8"	"930"	"103.5"	"5.97"	"3213.86"	"25.08"	"8"	"8"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00641, Pf01585, Pf17780"	"8241"	"ENSG00000182872"	"RBM10"	"A0A0A0MR66; C4AM81; hsa:8241; P98175; Q14136; Q5JRR2; Q9BTE4; Q9BTX0; Q9NTB1"	""	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"2"	"1"	"766.8"	"488.6"	"602.9"	"734.2"	"727.7"	"819.7"	"1593.0"	"1424.7"	"908.6"	"1401.5"	"1839.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14126"	"Desmoglein-2 OS=Homo sapiens OX=9606 GN=DSG2 PE=1 SV=2"	"8"	"7"	"14"	"7"	"1118"	"122.2"	"5.24"	"2713.38"	"25.08"	"7"	"7"	"cell adhesion;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00028"	"1829"	"ENSG00000046604"	"DSG2"	"hsa:1829; Q14126; Q4KKU6"	"Arrhythmogenic right ventricular cardiomyopathy; GDNF signaling"	"Formation of the cornified envelope; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; Apoptotic cleavage of cell adhesion  proteins"	"8"	"0"	"489.7"	"314.8"	"385.0"	"306.5"	"386.6"	"418.6"	"583.1"	"571.0"	"499.8"	"695.9"	"929.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23528"	"Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3"	"50"	"9"	"18"	"8"	"166"	"18.5"	"8.09"	"3583.65"	"25.07"	"8"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf00241"	"1072"	"ENSG00000172757"	"CFL1"	"B3KUQ1; hsa:1072; P23528; Q53Y87; Q9UCA2"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; VEGFA-VEGFR2 signaling; EGF/EGFR signaling pathway; Envelope proteins and their potential roles in EDMD physiopathology; 7q11.23 copy number variation syndrome; Neuroinflammation and glutamatergic signaling; CCL18 signaling pathway; Regulation of actin cytoskeleton; G13 signaling pathway"	"Regulation of actin dynamics for phagocytic cup formation; EPHB-mediated forward signaling; Platelet degranulation ; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Sema3A PAK dependent Axon repulsion; RHO GTPases Activate ROCKs"	"15"	"2"	"1999.8"	"1179.3"	"2007.9"	"1158.1"	"1618.1"	"1912.7"	"2435.0"	"1877.7"	"1525.0"	"2936.4"	"5361.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P32969"	"60S ribosomal protein L9 OS=Homo sapiens OX=9606 GN=RPL9 PE=1 SV=1"	"42"	"5"	"11"	"5"	"192"	"21.9"	"9.95"	"2195.10"	"25.04"	"4"	"5"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00347"	"6133"	"ENSG00000163682"	"RPL9; RPL9P7; RPL9P8; RPL9P9"	"hsa:6133; P32969"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"202.5"	"151.7"	"183.1"	"158.5"	"168.9"	"181.6"	"501.1"	"450.2"	"321.9"	"554.0"	"696.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02878"	"60S ribosomal protein L6 OS=Homo sapiens OX=9606 GN=RPL6 PE=1 SV=3"	"29"	"9"	"19"	"9"	"288"	"32.7"	"10.58"	"3363.88"	"24.98"	"9"	"7"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01159, Pf03868"	"6128"	"ENSG00000089009"	"RPL6"	"hsa:6128; Q02878; Q2M3Q3; Q8WW97"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"1438.5"	"883.2"	"1091.8"	"982.6"	"1112.3"	"1133.6"	"4566.2"	"4151.8"	"2779.3"	"4251.5"	"4990.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P28370"	"Probable global transcription activator SNF2L1 OS=Homo sapiens OX=9606 GN=SMARCA1 PE=1 SV=2"	"8"	"10"	"19"	"2"	"1054"	"122.5"	"8.09"	"2766.20"	"24.95"	"9"	"10"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf09110, Pf09111"	"6594"	"ENSG00000102038"	"SMARCA1"	"hsa:6594; P28370; Q5JV41; Q5JV42"	"Nuclear receptors meta-pathway; Rett syndrome causing genes"	""	"2"	"0"	"69.9"	"44.9"	"84.0"	"71.3"	"88.8"	"82.2"	"213.9"	"214.8"	"180.9"	"304.2"	"376.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6PD62"	"RNA polymerase-associated protein CTR9 homolog OS=Homo sapiens OX=9606 GN=CTR9 PE=1 SV=1"	"8"	"10"	"16"	"10"	"1173"	"133.4"	"6.77"	"2334.17"	"24.93"	"8"	"8"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf13181"	"9646"	"ENSG00000198730"	"CTR9"	"D3DQV8; hsa:9646; Q15015; Q6PD62"	"Endoderm differentiation"	"E3 ubiquitin ligases ubiquitinate target proteins; Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events"	"5"	"0"	"666.6"	"363.8"	"549.9"	"488.2"	"558.2"	"594.1"	"1643.3"	"1540.5"	"1159.3"	"1738.1"	"2259.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43795"	"Unconventional myosin-Ib OS=Homo sapiens OX=9606 GN=MYO1B PE=1 SV=3"	"7"	"7"	"15"	"6"	"1136"	"131.9"	"9.38"	"2399.94"	"24.68"	"6"	"7"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00063, Pf00612, Pf06017"	"4430"	"ENSG00000128641"	"MYO1B"	"hsa:4430; O43794; O43795; Q7Z6L5"	""	""	"0"	"0"	"199.0"	"134.2"	"203.3"	"177.2"	"188.1"	"225.8"	"386.7"	"445.8"	"362.6"	"660.1"	"808.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12236"	"ADP/ATP translocase 3 OS=Homo sapiens OX=9606 GN=SLC25A6 PE=1 SV=4"	"26"	"8"	"19"	"1"	"298"	"32.8"	"9.74"	"3034.41"	"24.65"	"8"	"7"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity"	"Pf00153"	"293"	"ENSG00000169100"	"SLC25A6"	"hsa:293; P12236; Q96C49"	"Electron transport chain: OXPHOS system in mitochondria; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Mitochondrial protein import; Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane; Influenza Virus Induced Apoptosis; Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization"	"7"	"1"	"54.7"	"24.7"	"43.5"	"37.9"	"45.6"	"38.0"	"84.6"	"75.8"	"62.4"	"109.1"	"154.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00535"	"Cyclin-dependent-like kinase 5 OS=Homo sapiens OX=9606 GN=CDK5 PE=1 SV=3"	"27"	"6"	"15"	"6"	"292"	"33.3"	"7.66"	"2602.85"	"24.59"	"5"	"6"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;kinase activity;other molecular function"	"Pf00069"	"1020"	"ENSG00000164885"	"CDK5"	"A1XKG3; hsa:1020; Q00535"	"miRNA regulation of DNA damage response; Nicotine effect on dopaminergic neurons; Alzheimer's disease and miRNA effects; Brain-derived neurotrophic factor (BDNF) signaling pathway; ATM signaling in development and disease ; Alzheimer's disease; Neurogenesis regulation in the olfactory epithelium; DNA damage response"	"NPAS4 regulates expression of target genes; NGF-stimulated transcription; Regulation of TP53 Activity through Phosphorylation; Factors involved in megakaryocyte development and platelet production; CRMPs in Sema3A signaling; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models; DARPP-32 events; Activated NTRK2 signals through CDK5"	"16"	"0"	"235.5"	"147.0"	"212.3"	"213.2"	"218.9"	"258.4"	"739.6"	"1305.7"	"1306.2"	"2342.2"	"3057.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07355"	"Annexin A2 OS=Homo sapiens OX=9606 GN=ANXA2 PE=1 SV=2"	"26"	"8"	"15"	"8"	"339"	"38.6"	"7.75"	"2673.84"	"24.55"	"7"	"8"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"non-structural extracellular;extracellular matrix;plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"transporter activity;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00191"	"302"	"ENSG00000182718"	"ANXA2"	"hsa:302; P07355; Q567R4; Q6N0B3; Q8TBV2; Q96DD5; Q9UDH8"	"Gastrin signaling pathway; CCL18 signaling pathway; Prostaglandin synthesis and regulation"	"Neutrophil degranulation; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Smooth Muscle Contraction; Dissolution of Fibrin Clot"	"7"	"0"	"256.0"	"126.7"	"332.0"	"215.4"	"247.3"	"250.6"	"1098.3"	"983.6"	"797.2"	"1546.7"	"2358.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N1F7"	"Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2"	"10"	"8"	"17"	"8"	"819"	"93.4"	"5.72"	"2825.30"	"24.54"	"8"	"8"	"cell organization and biogenesis;other metabolic processes;transport;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus"	"other molecular function"	"Pf04097"	"9688"	"ENSG00000102900"	"NUP93"	"B3KPQ8; hsa:9688; Q14705; Q8N1F7"	""	"SUMOylation of DNA replication proteins; Regulation of HSF1-mediated heat shock response; HCMV Early Events; Transport of Mature mRNA derived from an Intron-Containing Transcript; HCMV Late Events; Transcriptional regulation by small RNAs; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Postmitotic nuclear pore complex (NPC) reformation"	"29"	"0"	"774.4"	"486.9"	"664.6"	"723.4"	"791.2"	"845.4"	"1180.8"	"1079.4"	"783.4"	"1482.5"	"1846.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12277"	"Creatine kinase B-type OS=Homo sapiens OX=9606 GN=CKB PE=1 SV=1"	"23"	"7"	"14"	"7"	"381"	"42.6"	"5.59"	"2213.76"	"24.38"	"6"	"6"	"other metabolic processes;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00217, Pf02807"	"1152"	"ENSG00000166165"	"CKB"	"A8K236; B2R5R4; hsa:1152; P12277; Q2LE07; Q6FG40; Q9UC66"	""	"RND3 GTPase cycle; Creatine metabolism"	"2"	"0"	"660.6"	"576.4"	"782.8"	"392.7"	"611.7"	"651.1"	"782.3"	"554.8"	"435.6"	"853.9"	"1113.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06576"	"ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3"	"16"	"7"	"16"	"7"	"529"	"56.5"	"5.40"	"2940.34"	"24.23"	"7"	"7"	"other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"signal transduction activity or receptor binding;transporter activity;other molecular function"	"Pf00006, Pf02874"	"506"	"ENSG00000110955"	"ATP5F1B"	"A8K4X0; hsa:506; P06576; Q14283"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"Transcriptional activation of mitochondrial biogenesis; Mitochondrial protein import; Cristae formation; Formation of ATP by chemiosmotic coupling"	"7"	"0"	"520.7"	"319.7"	"436.5"	"343.4"	"431.4"	"465.9"	"680.1"	"719.5"	"486.5"	"843.1"	"1054.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55084"	"Trifunctional enzyme subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=HADHB PE=1 SV=3"	"19"	"10"	"18"	"10"	"474"	"51.3"	"9.41"	"3976.73"	"24.23"	"10"	"8"	"other metabolic processes;other biological processes"	"other membranes;mitochondrion;ER/Golgi"	"nucleic acid binding activity;other molecular function"	"Pf00108, Pf02803"	"3032"	"ENSG00000138029"	"HADHB"	"B2RB16; B4E2W0; hsa:3032; O14969; P55084; Q53TA6; Q96C77; Q9H3F5; Q9T2V8"	"Fatty acid beta-oxidation; Valproic acid pathway; Female steroid hormones in cardiomyocyte energy metabolism; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Acyl chain remodeling of CL; mitochondrial fatty acid beta-oxidation of unsaturated fatty acids; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of myristoyl-CoA to lauroyl-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA; Beta oxidation of palmitoyl-CoA to myristoyl-CoA"	"12"	"0"	"1304.6"	"808.5"	"1053.3"	"828.8"	"1043.6"	"1096.5"	"2214.6"	"1903.9"	"1363.2"	"2363.9"	"3158.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07737"	"Profilin-1 OS=Homo sapiens OX=9606 GN=PFN1 PE=1 SV=2"	"47"	"6"	"17"	"6"	"140"	"15.0"	"8.27"	"3150.66"	"23.93"	"6"	"6"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00235"	"5216"	"ENSG00000108518"	"PFN1"	"hsa:5216; P07737; Q53Y44"	"Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Burn wound healing; Regulation of actin cytoskeleton; G13 signaling pathway"	"RHO GTPases Activate Formins; Platelet degranulation ; PCP/CE pathway; Signaling by ROBO receptors"	"9"	"0"	"627.1"	"449.5"	"781.7"	"398.1"	"559.8"	"681.2"	"757.8"	"577.9"	"468.6"	"816.0"	"1336.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26639"	"Threonine--tRNA ligase 1, cytoplasmic OS=Homo sapiens OX=9606 GN=TARS1 PE=1 SV=3"	"13"	"8"	"10"	"8"	"723"	"83.4"	"6.67"	"635.75"	"23.77"	"2"	"8"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol"	"nucleic acid binding activity;other molecular function"	"Pf00587, Pf02824, Pf03129, Pf07973"	"6897"	"ENSG00000113407"	"TARS1"	"A8K8I1; B4DEG8; hsa:6897; P26639; Q96FP5; Q9BWA6"	""	"Cytosolic tRNA aminoacylation"	"1"	"0"	"134.2"	"104.5"	"170.7"	"167.3"	"172.3"	"172.3"	"414.7"	"390.2"	"325.2"	"871.5"	"2926.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96AG4"	"Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1"	"20"	"5"	"10"	"5"	"307"	"34.9"	"9.57"	"1564.94"	"23.76"	"3"	"5"	""	"other membranes;mitochondrion;ER/Golgi;nucleus;other cell component"	""	"Pf13855"	"55379"	"ENSG00000108829"	"LRRC59"	"B2RE83; D3DTX8; hsa:55379; Q96AG4; Q9P189"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"323.0"	"212.9"	"302.6"	"260.1"	"335.5"	"307.2"	"1200.5"	"1210.9"	"1142.4"	"2263.1"	"2697.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15084"	"Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1"	"16"	"6"	"13"	"6"	"440"	"48.1"	"5.08"	"2506.83"	"23.71"	"5"	"6"	"protein metabolism;other metabolic processes;stress response"	"non-structural extracellular;plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00085"	"10130"	"ENSG00000143870"	"PDIA6"	"B3KY95; B5MCQ5; B7Z254; B7Z4M8; F8WA83; hsa:10130; Q15084; Q53RC7; Q6ZSH5; Q99778"	"Photodynamic therapy-induced unfolded protein response; VEGFA-VEGFR2 signaling"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; XBP1(S) activates chaperone genes"	"5"	"0"	"704.3"	"402.7"	"622.5"	"801.3"	"737.8"	"815.7"	"1146.9"	"1138.6"	"836.2"	"982.4"	"1094.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00422"	"Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1"	"57"	"8"	"18"	"8"	"153"	"17.6"	"9.35"	"3680.26"	"23.65"	"6"	"6"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf06487"	"10284"	"ENSG00000150459"	"SAP18"	"B2R494; hsa:10284; O00422; Q2TTR4; Q6IAW9; Q8N606; Q9UF14; X6RAL5"	"Hedgehog signaling pathway"	"Potential therapeutics for SARS; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; mRNA Splicing - Major Pathway"	"5"	"0"	"1057.5"	"747.9"	"914.2"	"870.7"	"1100.0"	"1111.5"	"2242.5"	"2173.4"	"2049.7"	"4446.4"	"5938.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14240"	"Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2"	"17"	"8"	"19"	"1"	"407"	"46.4"	"5.48"	"3497.46"	"23.65"	"8"	"6"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"1974"	"ENSG00000156976"	"EIF4A2"	"D3DNU9; hsa:1974; Q14240; Q53XJ6; Q96B90; Q96EA8"	"Translation factors; Translation inhibitors in chronically activated PDGFRA cells"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Deadenylation of mRNA; ISG15 antiviral mechanism; Translation initiation complex formation; Ribosomal scanning and start codon recognition"	"9"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92917"	"G-patch domain and KOW motifs-containing protein OS=Homo sapiens OX=9606 GN=GPKOW PE=1 SV=2"	"17"	"6"	"11"	"6"	"476"	"52.2"	"6.15"	"1931.95"	"23.58"	"4"	"5"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00467, Pf12656"	"27238"	"ENSG00000068394"	"GPKOW"	"hsa:27238; Q59EK5; Q92917; Q9BQA8"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"199.2"	"127.2"	"170.3"	"185.7"	"175.9"	"213.4"	"406.6"	"392.8"	"298.6"	"583.7"	"912.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13243"	"Serine/arginine-rich splicing factor 5 OS=Homo sapiens OX=9606 GN=SRSF5 PE=1 SV=1"	"19"	"7"	"14"	"6"	"272"	"31.2"	"11.59"	"1699.62"	"23.54"	"5"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00076"	"6430"	"ENSG00000100650"	"SRSF5"	"hsa:6430; O14797; Q13243; Q16662; Q49AD6; Q6FGE0"	"mRNA processing"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"6"	"0"	"665.9"	"394.8"	"604.4"	"540.5"	"623.6"	"596.1"	"1608.3"	"1563.2"	"1120.3"	"1551.1"	"2133.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43660"	"Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1"	"20"	"7"	"12"	"7"	"514"	"57.2"	"9.17"	"2421.04"	"23.51"	"5"	"6"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	""	"Pf00400"	"5356"	"ENSG00000171566"	"PLRG1"	"B3KMK4; hsa:5356; O43660; Q3KQY5; Q8WUD8"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"279.1"	"191.1"	"349.6"	"257.9"	"308.2"	"312.2"	"1679.0"	"1561.6"	"1062.0"	"1953.8"	"2552.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18583"	"Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4"	"3"	"7"	"16"	"7"	"2426"	"263.7"	"5.64"	"2771.37"	"23.50"	"7"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf01585, Pf14709, Pf17069"	"6651"	"ENSG00000159140"	"SON"	"D3DSF5; D3DSF6; E7ETE8; E7EU67; E7EVW3; E9PFQ2; hsa:6651; O14487; O95981; P18583; Q14120; Q6PKE0; Q9H7B1; Q9P070; Q9P072; Q9UKP9; Q9UPY0"	""	""	"0"	"0"	"495.0"	"317.9"	"341.8"	"320.4"	"406.2"	"425.8"	"848.3"	"645.0"	"505.6"	"916.8"	"1210.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L7X3"	"Serine/threonine-protein kinase TAO1 OS=Homo sapiens OX=9606 GN=TAOK1 PE=1 SV=1"	"6"	"5"	"13"	"3"	"1001"	"116.0"	"7.65"	"2429.44"	"23.49"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;cytoskeletal activity;kinase activity;other molecular function"	"Pf00069"	"57551"	"ENSG00000160551"	"TAOK1"	"A2RUT8; B7ZLV6; hsa:57551; Q7L7X3; Q96L75; Q9H2K7; Q9H7S5; Q9P2I6"	"Microtubule cytoskeleton regulation; MAPK signaling pathway"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"8"	"2"	"80.8"	"55.6"	"136.5"	"80.7"	"86.6"	"96.1"	"303.4"	"354.2"	"265.8"	"443.5"	"629.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86UE4"	"Protein LYRIC OS=Homo sapiens OX=9606 GN=MTDH PE=1 SV=2"	"15"	"7"	"12"	"7"	"582"	"63.8"	"9.32"	"2816.37"	"23.46"	"6"	"6"	"signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf15686"	"92140"	"ENSG00000147649"	"MTDH"	"hsa:92140; Q05DH2; Q52QU9; Q6PK07; Q86UE4; Q8TCX3"	"Gastric cancer network 2; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; CCL18 signaling pathway"	""	"3"	"0"	"417.6"	"232.3"	"327.7"	"326.6"	"345.4"	"355.5"	"1124.6"	"1042.7"	"826.1"	"1487.9"	"2791.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43290"	"U4/U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1"	"13"	"7"	"13"	"7"	"800"	"90.2"	"6.13"	"2598.27"	"23.44"	"6"	"7"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	""	"Pf03343, Pf19252"	"9092"	"ENSG00000175467"	"SART1"	"A6NDN1; hsa:9092; O43290; Q53GB5"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"213.0"	"154.4"	"193.1"	"195.3"	"200.8"	"221.7"	"522.2"	"449.4"	"332.4"	"585.6"	"698.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75369"	"Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2"	"4"	"7"	"12"	"7"	"2602"	"278.0"	"5.73"	"2068.45"	"23.38"	"6"	"6"	"cell organization and biogenesis;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00630"	"2317"	"ENSG00000136068"	"FLNB"	"B2ZZ83; B2ZZ84; B2ZZ85; C9JKE6; C9JMC4; hsa:2317; O75369; Q13706; Q59EC2; Q60FE7; Q6MZJ1; Q8WXS9; Q8WXT0; Q8WXT1; Q8WXT2; Q8WXT3; Q9NRB5; Q9NT26; Q9UEV9"	"Focal adhesion; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Ebola virus infection in host; NPHP1 deletion syndrome"	"ISG15 antiviral mechanism"	"6"	"0"	"269.0"	"180.2"	"275.1"	"238.9"	"265.1"	"293.6"	"501.3"	"447.5"	"342.1"	"553.7"	"749.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12814"	"Alpha-actinin-1 OS=Homo sapiens OX=9606 GN=ACTN1 PE=1 SV=2"	"9"	"6"	"14"	"3"	"892"	"103.0"	"5.41"	"2561.97"	"23.36"	"6"	"6"	"cell adhesion;cell organization and biogenesis;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00307, Pf00435, Pf08726"	"87"	"ENSG00000072110"	"ACTN1"	"B3V8S3; B4DHH3; B7TY16; hsa:87; P12814; Q1HE25; Q9BTN1"	"Arrhythmogenic right ventricular cardiomyopathy; Focal adhesion; Ebola virus infection in host; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Regulation of actin cytoskeleton"	"RHOD GTPase cycle; RHOF GTPase cycle; Platelet degranulation ; Nephrin family interactions; Syndecan interactions; RHOBTB2 GTPase cycle; Regulation of cytoskeletal remodeling and cell spreading by IPP complex components"	"12"	"0"	"59.4"	"40.1"	"71.4"	"47.2"	"56.9"	"57.0"	"103.4"	"82.7"	"64.1"	"109.2"	"179.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00505"	"Importin subunit alpha-4 OS=Homo sapiens OX=9606 GN=KPNA3 PE=1 SV=2"	"15"	"6"	"12"	"3"	"521"	"57.8"	"4.94"	"2214.23"	"23.36"	"5"	"5"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf01749, Pf16186"	"3839"	"ENSG00000102753"	"KPNA3"	"hsa:3839; O00191; O00505; O43195; Q5JVM9; Q8IYQ9; Q96AA7"	""	"ISG15 antiviral mechanism; NS1 Mediated Effects on Host Pathways"	"2"	"3"	"447.0"	"240.8"	"363.4"	"378.1"	"397.1"	"389.0"	"615.2"	"599.1"	"426.8"	"652.8"	"919.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13595"	"Transformer-2 protein homolog alpha OS=Homo sapiens OX=9606 GN=TRA2A PE=1 SV=1"	"17"	"6"	"16"	"5"	"282"	"32.7"	"11.27"	"2509.17"	"23.35"	"6"	"6"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00076"	"29896"	"ENSG00000164548"	"TRA2A"	"B4DQI6; B4DUA9; E9PD75; hsa:29896; Q13595"	"Orexin receptor pathway"	""	"1"	"1"	"647.2"	"407.8"	"560.0"	"425.0"	"613.3"	"547.2"	"1117.5"	"1108.2"	"1389.3"	"3052.5"	"4365.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92688"	"Acidic leucine-rich nuclear phosphoprotein 32 family member B OS=Homo sapiens OX=9606 GN=ANP32B PE=1 SV=1"	"27"	"7"	"14"	"5"	"251"	"28.8"	"4.06"	"2260.00"	"23.31"	"6"	"5"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf12799"	"10541"	"ENSG00000136938"	"ANP32B"	"B2R9C7; hsa:10541; O00655; P78458; P78459; Q92688"	""	""	"0"	"2"	"864.9"	"473.2"	"707.6"	"588.4"	"648.9"	"630.6"	"3152.1"	"2777.1"	"1839.0"	"2440.0"	"3339.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25685"	"DnaJ homolog subfamily B member 1 OS=Homo sapiens OX=9606 GN=DNAJB1 PE=1 SV=4"	"19"	"6"	"14"	"6"	"340"	"38.0"	"8.63"	"2682.40"	"23.30"	"6"	"6"	"protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00226, Pf01556"	"3337"	"ENSG00000132002"	"DNAJB1"	"B4DX52; hsa:3337; P25685"	"Nuclear receptors meta-pathway; NRF2 pathway"	"MAPK6/MAPK4 signaling; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Regulation of HSF1-mediated heat shock response; Attenuation phase"	"7"	"0"	"338.2"	"169.1"	"243.2"	"289.7"	"272.6"	"318.6"	"1826.0"	"1838.0"	"1212.4"	"1779.8"	"2113.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P2T1"	"GMP reductase 2 OS=Homo sapiens OX=9606 GN=GMPR2 PE=1 SV=1"	"22"	"6"	"10"	"5"	"348"	"37.9"	"7.23"	"1041.75"	"23.23"	"2"	"6"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00478"	"51292"	"ENSG00000100938; ENSG00000284752"	"GMPR2"	"D3DS66; hsa:51292; Q567T0; Q6IAJ8; Q86T14; Q9P2T1"	""	"Purine salvage"	"1"	"1"	"143.8"	"87.5"	"176.5"	"128.2"	"160.0"	"199.0"	"347.6"	"529.4"	"1066.6"	"3113.2"	"4441.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15160"	"DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1"	"28"	"7"	"14"	"7"	"346"	"39.2"	"5.50"	"2217.13"	"23.22"	"5"	"7"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01000, Pf01193"	"9533"	"ENSG00000171453"	"POLR1C"	"hsa:9533; O15160; O75395; Q5JTE3"	"Pyrimidine metabolism; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"15"	"0"	"266.5"	"198.2"	"252.1"	"310.7"	"289.6"	"342.1"	"700.2"	"1592.0"	"1966.6"	"3425.0"	"3944.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11940"	"Polyadenylate-binding protein 1 OS=Homo sapiens OX=9606 GN=PABPC1 PE=1 SV=2"	"11"	"7"	"16"	"5"	"636"	"70.6"	"9.50"	"2599.55"	"23.21"	"7"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf00658"	"26986"	"ENSG00000070756"	"PABPC1"	"hsa:26986; P11940; Q15097; Q93004"	"Translation factors; Endoderm differentiation; VEGFA-VEGFR2 signaling; Acute viral myocarditis"	"AUF1 (hnRNP D0) binds and destabilizes mRNA; Regulation of expression of SLITs and ROBOs; Deadenylation of mRNA; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"11"	"2"	"904.1"	"567.2"	"796.2"	"756.9"	"848.0"	"883.8"	"1711.8"	"1567.0"	"1168.9"	"1842.8"	"2376.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P10412"	"Histone H1.4 OS=Homo sapiens OX=9606 GN=H1-4 PE=1 SV=2"	"34"	"9"	"18"	"1"	"219"	"21.9"	"11.03"	"3650.04"	"23.18"	"9"	"7"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00538"	"3008"	"ENSG00000168298"	"H1-4"	"hsa:3008; P10412; Q4VB25"	"Pathways affected in adenoid cystic carcinoma"	"Apoptosis induced DNA fragmentation; Formation of Senescence-Associated Heterochromatin Foci (SAHF)"	"3"	"8"	"1096.6"	"581.5"	"812.8"	"772.8"	"893.9"	"848.5"	"4643.9"	"4135.9"	"3106.1"	"4523.8"	"4918.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P16403"	"Histone H1.2 OS=Homo sapiens OX=9606 GN=H1-2 PE=1 SV=2"	"31"	"8"	"17"	"1"	"213"	"21.4"	"10.93"	"3217.81"	"23.18"	"8"	"7"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00538"	"3006"	"ENSG00000187837"	"H1-2"	"A8K4I2; hsa:3006; P16403"	""	"Apoptosis induced DNA fragmentation; Formation of Senescence-Associated Heterochromatin Foci (SAHF)"	"2"	"0"	"105.7"	"48.8"	"74.5"	"66.0"	"82.3"	"74.9"	"340.8"	"319.6"	"252.2"	"378.8"	"449.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60306"	"RNA helicase aquarius OS=Homo sapiens OX=9606 GN=AQR PE=1 SV=4"	"5"	"6"	"14"	"6"	"1485"	"171.2"	"6.37"	"2622.69"	"23.16"	"6"	"6"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13086, Pf13087, Pf16399"	"9716"	"ENSG00000021776"	"AQR"	"A0JP17; A5YKK3; hsa:9716; O60306; Q2YDX9; Q6IRU8; Q6PIC8"	""	"mRNA Splicing - Major Pathway; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	"5"	"0"	"168.6"	"131.6"	"195.9"	"164.1"	"200.1"	"205.8"	"307.6"	"263.4"	"222.5"	"363.2"	"452.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TBX8"	"Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma OS=Homo sapiens OX=9606 GN=PIP4K2C PE=1 SV=3"	"18"	"7"	"15"	"7"	"421"	"47.3"	"6.84"	"2225.57"	"23.12"	"6"	"7"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf01504"	"79837"	"ENSG00000166908"	"PIP4K2C"	"B2RDL3; B4DM11; B4DY44; hsa:79837; Q8TBX8; Q9H6N2"	"Regulation of actin cytoskeleton"	"Synthesis of PIPs at the plasma membrane; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; PI5P Regulates TP53 Acetylation; Synthesis of PIPs in the nucleus"	"5"	"0"	"195.5"	"137.2"	"170.3"	"216.6"	"211.0"	"236.0"	"882.2"	"1528.1"	"1779.5"	"3578.5"	"4247.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55081"	"Microfibrillar-associated protein 1 OS=Homo sapiens OX=9606 GN=MFAP1 PE=1 SV=2"	"17"	"8"	"12"	"8"	"439"	"51.9"	"4.98"	"2368.85"	"23.08"	"5"	"7"	"RNA metabolism OR transcription;other metabolic processes"	"extracellular matrix;cytoskeleton;nucleus"	""	"Pf06991"	"4236"	"ENSG00000140259"	"MFAP1"	"hsa:4236; P55081; Q86TG6"	"Canonical and non-canonical Notch signaling; Ciliary landscape"	"mRNA Splicing - Major Pathway"	"3"	"0"	"938.4"	"464.2"	"608.8"	"674.6"	"645.9"	"839.5"	"1860.3"	"1658.0"	"1224.1"	"2017.9"	"2887.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14166"	"Tubulin--tyrosine ligase-like protein 12 OS=Homo sapiens OX=9606 GN=TTLL12 PE=1 SV=2"	"14"	"6"	"10"	"6"	"644"	"74.4"	"5.53"	"1412.36"	"23.00"	"4"	"6"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03133"	"23170"	"ENSG00000100304"	"TTLL12"	"hsa:23170; Q14166; Q20WK5; Q9UGU3"	""	"Carboxyterminal post-translational modifications of tubulin"	"1"	"0"	"248.0"	"139.6"	"190.8"	"187.2"	"193.6"	"187.7"	"365.4"	"368.8"	"296.4"	"420.9"	"491.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3A5"	"Ribosome maturation protein SBDS OS=Homo sapiens OX=9606 GN=SBDS PE=1 SV=4"	"30"	"7"	"11"	"7"	"250"	"28.7"	"8.75"	"1482.53"	"22.96"	"4"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;translation activity;nucleic acid binding activity"	"Pf01172, Pf09377, Pf20268"	"51119"	"ENSG00000126524"	"SBDS"	"A8K0P4; hsa:51119; Q96FX0; Q9NV53; Q9Y3A5"	"Genetic causes of porto-sinusoidal vascular disease"	""	"1"	"0"	"157.1"	"120.5"	"183.7"	"164.3"	"199.1"	"190.3"	"908.7"	"992.4"	"898.7"	"2157.8"	"4414.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20073"	"Annexin A7 OS=Homo sapiens OX=9606 GN=ANXA7 PE=1 SV=3"	"17"	"7"	"15"	"7"	"488"	"52.7"	"5.68"	"2505.65"	"22.90"	"6"	"7"	"other metabolic processes;other biological processes"	"other membranes;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00191"	"310"	"ENSG00000138279"	"ANXA7"	"hsa:310; P20073; Q5F2H3; Q5T0M6; Q5T0M7"	""	""	"0"	"0"	"450.8"	"201.7"	"277.8"	"331.4"	"267.9"	"343.3"	"488.7"	"435.6"	"365.7"	"539.8"	"735.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NFH4"	"Nucleoporin Nup37 OS=Homo sapiens OX=9606 GN=NUP37 PE=1 SV=1"	"24"	"6"	"12"	"6"	"326"	"36.7"	"5.92"	"2600.00"	"22.82"	"6"	"6"	"cell cycle OR cell proliferation;transport;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00400"	"79023"	"ENSG00000075188"	"NUP37"	"hsa:79023; Q8NFH4; Q9H644"	""	"Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Regulation of HSF1-mediated heat shock response; ISG15 antiviral mechanism; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Vpr-mediated nuclear import of PICs; SUMOylation of DNA damage response and repair proteins; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transport of Mature mRNA derived from an Intron-Containing Transcript; tRNA processing in the nucleus; HCMV Late Events; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; HCMV Early Events; EML4 and NUDC in mitotic spindle formation; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; snRNP Assembly; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); SARS-CoV-2 activates/modulates innate and adaptive immune responses; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Postmitotic nuclear pore complex (NPC) reformation"	"35"	"0"	"360.0"	"254.0"	"361.5"	"419.1"	"407.3"	"374.9"	"755.3"	"699.3"	"515.0"	"864.1"	"1155.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18859"	"ATP synthase-coupling factor 6, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PF PE=1 SV=1"	"36"	"3"	"9"	"3"	"108"	"12.6"	"9.52"	"2057.39"	"22.78"	"2"	"3"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf05511"	"522"	"ENSG00000154723"	"ATP5PF"	"hsa:522; J3KQ83; P18859"	"Electron transport chain: OXPHOS system in mitochondria; Oxidative phosphorylation"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"4"	"0"	"135.9"	"110.0"	"122.0"	"138.5"	"137.0"	"150.3"	"234.7"	"224.1"	"173.6"	"281.2"	"418.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y285"	"Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3"	"12"	"7"	"15"	"7"	"508"	"57.5"	"7.80"	"2346.76"	"22.76"	"6"	"7"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01409, Pf18552, Pf18553, Pf18554"	"2193"	"ENSG00000179115"	"FARSA"	"B4E363; hsa:2193; Q9NSD8; Q9Y285; Q9Y4W8"	""	"Cytosolic tRNA aminoacylation"	"1"	"0"	"292.6"	"222.0"	"311.8"	"271.6"	"308.6"	"325.3"	"1025.5"	"1044.0"	"800.4"	"1163.3"	"1467.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50502"	"Hsc70-interacting protein OS=Homo sapiens OX=9606 GN=ST13 PE=1 SV=2"	"22"	"8"	"16"	"8"	"369"	"41.3"	"5.27"	"3182.10"	"22.76"	"8"	"7"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf17830, Pf18253"	"6767"	"ENSG00000100380"	"ST13"	"hsa:6767; O14999; P50502; Q2TU77"	""	"Regulation of HSF1-mediated heat shock response"	"1"	"0"	"2487.6"	"883.8"	"1331.4"	"1832.8"	"1412.6"	"1963.9"	"2115.8"	"1904.5"	"1309.2"	"2124.7"	"3472.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12268"	"Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2"	"17"	"7"	"14"	"7"	"514"	"55.8"	"6.90"	"3439.43"	"22.57"	"7"	"6"	"cell cycle OR cell proliferation;other metabolic processes;developmental processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00478, Pf00571"	"3615"	"ENSG00000178035"	"IMPDH2"	"hsa:3615; P12268; Q6LEF3"	"Rett syndrome causing genes"	"Potential therapeutics for SARS; Neutrophil degranulation; Purine ribonucleoside monophosphate biosynthesis; Azathioprine ADME"	"5"	"0"	"450.9"	"268.8"	"325.2"	"329.4"	"357.0"	"494.2"	"1070.6"	"1027.7"	"661.9"	"1043.0"	"1390.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9GZS1"	"DNA-directed RNA polymerase I subunit RPA49 OS=Homo sapiens OX=9606 GN=POLR1E PE=1 SV=3"	"14"	"6"	"12"	"6"	"419"	"47.2"	"8.94"	"1394.76"	"22.56"	"4"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf06870"	"64425"	"ENSG00000137054"	"POLR1E"	"hsa:64425; Q5VZT3; Q8NBA9; Q96L20; Q9GZS1"	"Pyrimidine metabolism; Eukaryotic transcription initiation; 2q13 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Initiation; RNA Polymerase I Transcription Termination"	"8"	"0"	"211.2"	"151.8"	"267.8"	"210.1"	"236.1"	"242.8"	"610.7"	"1210.5"	"1478.7"	"2605.5"	"3161.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14011"	"Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1"	"39"	"5"	"9"	"5"	"172"	"18.6"	"9.51"	"1006.09"	"22.52"	"3"	"5"	"cell organization and biogenesis;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"1153"	"ENSG00000099622"	"CIRBP"	"B3KT17; B4E2X2; hsa:1153; Q14011"	""	""	"0"	"0"	"272.6"	"205.1"	"227.4"	"217.2"	"248.4"	"221.1"	"574.4"	"553.9"	"499.8"	"676.5"	"760.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P16152"	"Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3"	"23"	"6"	"15"	"6"	"277"	"30.4"	"8.32"	"2332.05"	"22.50"	"5"	"6"	"other metabolic processes;other biological processes"	"cytosol"	"other molecular function"	"Pf00106"	"873"	"ENSG00000159228"	"CBR1"	"B2RBZ7; B4DFK7; hsa:873; P16152; Q3LHW8"	"Nuclear receptors meta-pathway; NRF2 pathway; Prostaglandin synthesis and regulation"	"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)"	"4"	"0"	"465.5"	"378.9"	"515.0"	"438.6"	"523.8"	"525.2"	"667.1"	"628.9"	"488.4"	"749.7"	"1037.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05387"	"60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1"	"31"	"4"	"12"	"4"	"115"	"11.7"	"4.54"	"2539.02"	"22.46"	"4"	"4"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf00428"	"6181"	"ENSG00000177600"	"RPLP2"	"hsa:6181; P05387; Q6FG96"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins; Opioid receptor pathways"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"16"	"0"	"373.0"	"219.7"	"310.2"	"224.3"	"265.2"	"335.8"	"902.4"	"789.0"	"575.5"	"1054.4"	"1396.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H307"	"Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5"	"14"	"8"	"14"	"8"	"717"	"81.6"	"7.14"	"3470.21"	"22.44"	"8"	"6"	"cell adhesion;RNA metabolism OR transcription;other metabolic processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04696, Pf04697"	"5411"	"ENSG00000100941"	"PNN"	"B4DZX8; hsa:5411; O60899; Q53EM7; Q6P5X4; Q7KYL1; Q99738; Q9H307; Q9UHZ9; Q9UQR9"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"492.6"	"315.6"	"378.6"	"351.8"	"467.1"	"469.8"	"820.4"	"616.0"	"551.2"	"1207.3"	"1674.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H3K6"	"BolA-like protein 2 OS=Homo sapiens OX=9606 GN=BOLA2 PE=1 SV=1"	"59"	"4"	"12"	"4"	"86"	"10.1"	"6.52"	"2402.37"	"22.40"	"4"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01722"	"552900; 654483"	"ENSG00000169627; ENSG00000183336"	"BOLA2; BOLA2B"	"A1L454; A7YDY3; hsa:552900; hsa:654483; Q9H3K6"	""	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"1"	"0"	"522.5"	"294.1"	"443.7"	"415.2"	"349.7"	"478.9"	"654.3"	"614.0"	"462.7"	"810.5"	"1405.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3Y2"	"Chromatin target of PRMT1 protein OS=Homo sapiens OX=9606 GN=CHTOP PE=1 SV=2"	"31"	"6"	"12"	"6"	"248"	"26.4"	"12.23"	"2532.78"	"22.33"	"5"	"5"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf13865"	"26097"	"ENSG00000160679"	"CHTOP"	"D3DV55; hsa:26097; Q0VAQ8; Q2VPI9; Q5T7Y8; Q5T7Y9; Q5T7Z0; Q6NSM4; Q6PB28; Q8WYT9; Q9BUC5; Q9H034; Q9H2L0; Q9Y3Y2"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"3"	"0"	"652.2"	"493.3"	"590.5"	"486.5"	"573.0"	"656.0"	"1246.9"	"1038.4"	"833.6"	"1608.7"	"1899.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61604"	"10 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPE1 PE=1 SV=2"	"66"	"8"	"21"	"8"	"102"	"10.9"	"8.92"	"3976.52"	"22.32"	"8"	"6"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"mitochondrion"	"other molecular function"	"Pf00166"	"3336"	"ENSG00000115541"	"HSPE1"	"hsa:3336; O95421; P61604; Q04984; Q53X54; Q9UDH0"	""	"RHOG GTPase cycle"	"1"	"0"	"1427.6"	"1299.6"	"1944.8"	"1587.5"	"1622.7"	"1650.4"	"2441.1"	"3135.7"	"1906.8"	"3532.9"	"6485.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62979"	"Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2"	"52"	"7"	"14"	"7"	"156"	"18.0"	"9.64"	"2726.85"	"22.28"	"5"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;translational apparatus;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00240, Pf01599"	"6233"	"ENSG00000143947"	"RPS27A"	"hsa:6233; P02248; P02249; P02250; P14798; P62979; P62988; Q29120; Q6LBL4; Q6LDU5; Q8WYN8; Q91887; Q91888; Q9BQ77; Q9BWD6; Q9BX98; Q9UEF2; Q9UEG1; Q9UEK8; Q9UPK7"	"Cytoplasmic ribosomal proteins"	"Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Aggrephagy; Oxidative Stress Induced Senescence; ISG15 antiviral mechanism; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Peroxisomal protein import; Degradation of GLI1 by the proteasome; Hedgehog 'on' state; Activated NOTCH1 Transmits Signal to the Nucleus; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery; E3 ubiquitin ligases ubiquitinate target proteins; Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Stimuli-sensing channels; Amyloid fiber formation; Fanconi Anemia Pathway; Budding and maturation of HIV virion; Membrane binding and targetting of GAG proteins; Endosomal Sorting Complex Required For Transport (ESCRT); Late endosomal microautophagy; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Regulation of PLK1 Activity at G2/M Transition; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; NOTCH2 Activation and Transmission of Signal to the Nucleus; NOTCH3 Activation and Transmission of Signal to the Nucleus; Regulation of TP53 Degradation; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Activation of IRF3, IRF7 mediated by TBK1, IKBKE; IKK complex recruitment mediated by RIP1; TRAF6-mediated induction of TAK1 complex within TLR4 complex; IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation; ER Quality Control Compartment (ERQC); SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Deactivation of the beta-catenin transactivating complex; Regulation of TP53 Activity through Phosphorylation; Circadian Clock; Regulation of signaling by CBL; Metalloprotease DUBs; Regulation of necroptotic cell death; Oncogene Induced Senescence; Cyclin D associated events in G1; APC/C:Cdc20 mediated degradation of Cyclin B; APC-Cdc20 mediated degradation of Nek2A; Senescence-Associated Secretory Phenotype (SASP); Negative regulation of FLT3; Downregulation of ERBB2:ERBB3 signaling; Cargo recognition for clathrin-mediated endocytosis; Interferon alpha/beta signaling; Inactivation of CSF3 (G-CSF) signaling; JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1; Regulation of TP53 Activity through Methylation; Processing of DNA double-strand break ends; Regulation of BACH1 activity; NOD1/2 Signaling Pathway; TICAM1, RIP1-mediated IKK complex recruitment; p75NTR recruits signalling complexes; NF-kB is activated and signals survival; TAK1-dependent IKK and NF-kappa-B activation  ; Regulation of TNFR1 signaling; TNFR1-induced NF-kappa-B signaling pathway; MAP3K8 (TPL2)-dependent MAPK1/3 activation; IRAK1 recruits IKK complex; IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation; Regulation of NF-kappa B signaling; Termination of translesion DNA synthesis; Negative regulators of DDX58/IFIH1 signaling; EGFR downregulation; Negative regulation of MET activity; InlB-mediated entry of Listeria monocytogenes into host cell; Prevention of phagosomal-lysosomal fusion; Downregulation of TGF-beta receptor signaling; Downregulation of SMAD2/3:SMAD4 transcriptional activity; HDR through Homologous Recombination (HRR); Signaling by CSF1 (M-CSF) in myeloid cells; NOTCH1 Intracellular Domain Regulates Transcription; TICAM1-dependent activation of IRF3/IRF7; TICAM1,TRAF6-dependent induction of TAK1 complex; Glycogen synthesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Modulation by Mtb of host immune system; activated TAK1 mediates p38 MAPK activation; IRAK2 mediated activation of TAK1 complex; SARS-CoV-1 activates/modulates innate immune responses; Alpha-protein kinase 1 signaling pathway; Ovarian tumor domain proteases; Spry regulation of FGF signaling; RAS processing; PINK1-PRKN Mediated Mitophagy; Josephin domain DUBs; Regulation of FZD by ubiquitination; Chaperone Mediated Autophagy; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; InlA-mediated entry of Listeria monocytogenes into host cells; Formation of Incision Complex in GG-NER; Iron uptake and transport; Recognition of DNA damage by PCNA-containing replication complex; VLDLR internalisation and degradation; Myoclonic epilepsy of Lafora; DNA Damage Recognition in GG-NER; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; Negative regulation of MAPK pathway; TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition); NRIF signals cell death from the nucleus; Assembly Of The HIV Virion; Dual Incision in GG-NER; Translesion Synthesis by POLH; Downregulation of ERBB4 signaling; Regulation of innate immune responses to cytosolic DNA; N-glycan trimming in the ER and Calnexin/Calreticulin cycle; Gap-filling DNA repair synthesis and ligation in GG-NER; PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1; Regulation of PTEN localization; Pexophagy; Maturation of protein E; Maturation of protein E; FLT3 signaling by CBL mutants; TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling"	"201"	"0"	"1876.9"	"1325.4"	"1642.4"	"1313.8"	"1622.8"	"1609.4"	"2959.6"	"2479.2"	"1848.4"	"3071.7"	"4072.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y265"	"RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1"	"17"	"6"	"14"	"6"	"456"	"50.2"	"6.42"	"2340.49"	"22.27"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf06068, Pf17856"	"8607"	"ENSG00000175792; ENSG00000284901"	"RUVBL1"	"B2R5S0; hsa:8607; P82276; Q1KMR0; Q53HK5; Q53HL7; Q53Y27; Q9BSX9; Q9Y265"	"Gastric cancer network 1; lncRNA in canonical Wnt signaling and colorectal cancer"	"DNA Damage Recognition in GG-NER; UCH proteinases; Ub-specific processing proteases; Formation of the beta-catenin:TCF transactivating complex; HATs acetylate histones; Deposition of new CENPA-containing nucleosomes at the centromere; Telomere Extension By Telomerase"	"9"	"0"	"169.6"	"114.4"	"154.6"	"108.0"	"138.4"	"141.7"	"228.0"	"187.6"	"128.6"	"267.0"	"385.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30419"	"Glycylpeptide N-tetradecanoyltransferase 1 OS=Homo sapiens OX=9606 GN=NMT1 PE=1 SV=2"	"14"	"5"	"11"	"5"	"496"	"56.8"	"7.80"	"2279.46"	"22.26"	"5"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf01233, Pf02799"	"4836"	"ENSG00000136448"	"NMT1"	"A8K7C1; hsa:4836; P30419; Q9UE09"	""	"Inactivation, recovery and regulation of the phototransduction cascade; Late Phase of HIV Life Cycle; Activation, myristolyation of BID and translocation to mitochondria"	"3"	"0"	"166.4"	"86.6"	"131.1"	"120.5"	"123.1"	"119.8"	"346.6"	"354.4"	"345.2"	"539.1"	"1054.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y262"	"Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1"	"14"	"8"	"17"	"8"	"564"	"66.7"	"6.34"	"2844.90"	"22.21"	"8"	"7"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity"	"Pf10255"	"51386"	"ENSG00000100129"	"EIF3L"	"B2RDG6; B4DYB2; G8JLH4; hsa:51386; Q53HQ1; Q53HT4; Q5QTR1; Q5TI15; Q6ICD2; Q9Y262"	""	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition"	"6"	"0"	"800.3"	"527.6"	"753.7"	"626.6"	"701.2"	"802.8"	"1308.6"	"1258.1"	"934.8"	"1459.4"	"2118.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P16989"	"Y-box-binding protein 3 OS=Homo sapiens OX=9606 GN=YBX3 PE=1 SV=4"	"24"	"6"	"11"	"3"	"372"	"40.1"	"9.77"	"2195.47"	"22.20"	"6"	"5"	"stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00313"	"8531"	"ENSG00000060138"	"YBX3"	"B2RBW6; hsa:8531; P16989; Q14121; Q969N6; Q96B76"	"RalA downstream regulated genes; Apoptosis-related network due to altered Notch3 in ovarian cancer"	""	"2"	"0"	"48.1"	"35.2"	"52.7"	"45.7"	"50.2"	"57.7"	"109.7"	"91.9"	"78.6"	"116.4"	"124.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NCB2"	"CaM kinase-like vesicle-associated protein OS=Homo sapiens OX=9606 GN=CAMKV PE=2 SV=2"	"13"	"6"	"14"	"6"	"501"	"54.3"	"5.55"	"2297.45"	"22.07"	"6"	"6"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"79012"	"ENSG00000164076"	"CAMKV"	"A6NFD4; hsa:79012; Q6FIB8; Q8NBS8; Q8NC85; Q8NCB2; Q8NDU4; Q8WTT8; Q9BQC9; Q9H0Q5"	""	""	"0"	"0"	"129.9"	"96.4"	"134.5"	"142.2"	"153.8"	"153.3"	"325.7"	"469.5"	"699.8"	"1416.5"	"1779.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BY44"	"Eukaryotic translation initiation factor 2A OS=Homo sapiens OX=9606 GN=EIF2A PE=1 SV=3"	"14"	"7"	"14"	"7"	"585"	"64.9"	"8.87"	"2536.90"	"22.05"	"6"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;translational apparatus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf08662"	"83939"	"ENSG00000144895"	"EIF2A"	"A8MPS6; B4DF96; B4DQ14; D3DNI9; hsa:83939; Q5QTR2; Q7Z4E9; Q8NFM1; Q96EW9; Q96K81; Q9BY44"	"Photodynamic therapy-induced unfolded protein response; VEGFA-VEGFR2 signaling; 7q11.23 copy number variation syndrome"	""	"3"	"0"	"393.2"	"204.4"	"337.1"	"293.8"	"339.4"	"335.4"	"1027.8"	"1006.6"	"837.0"	"1324.4"	"2060.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UHB6"	"LIM domain and actin-binding protein 1 OS=Homo sapiens OX=9606 GN=LIMA1 PE=1 SV=1"	"9"	"6"	"13"	"6"	"759"	"85.2"	"6.84"	"1979.93"	"21.99"	"5"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412"	"51474"	"ENSG00000050405"	"LIMA1"	"B2RB09; hsa:51474; Q2TAN7; Q59FE8; Q9BVF2; Q9H8J1; Q9HBN5; Q9NX96; Q9NXC3; Q9NXU6; Q9P0H8; Q9UHB5; Q9UHB6"	""	""	"0"	"0"	"651.6"	"268.8"	"385.1"	"478.7"	"443.1"	"558.0"	"1159.9"	"992.9"	"740.1"	"1103.5"	"1518.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30101"	"Protein disulfide-isomerase A3 OS=Homo sapiens OX=9606 GN=PDIA3 PE=1 SV=4"	"17"	"7"	"13"	"7"	"505"	"56.7"	"6.35"	"2182.12"	"21.98"	"6"	"7"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00085, Pf13848"	"2923"	"ENSG00000167004"	"PDIA3"	"hsa:2923; P30101; Q13453; Q14255; Q8IYF8; Q9UMU7"	"Prion disease pathway"	"ER-Phagosome pathway; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Calnexin/calreticulin cycle"	"4"	"0"	"439.2"	"370.0"	"514.1"	"432.3"	"497.4"	"539.5"	"1038.9"	"968.2"	"800.1"	"1171.9"	"1398.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49792"	"E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2"	"3"	"8"	"14"	"7"	"3224"	"358.0"	"6.20"	"1951.11"	"21.97"	"6"	"8"	"protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00160, Pf00638, Pf00641, Pf12185"	"5903"	"ENSG00000153201"	"RANBP2"	"hsa:5903; P49792; Q13074; Q15280; Q53TE2; Q59FH7"	""	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; HCMV Late Events; HCMV Early Events; Transcriptional regulation by small RNAs; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Signaling by ALK fusions and activated point mutants; tRNA processing in the nucleus; Viral Messenger RNA Synthesis; SUMOylation of DNA damage response and repair proteins; Rev-mediated nuclear export of HIV RNA; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"	"35"	"1"	"1139.3"	"593.8"	"850.9"	"782.9"	"789.3"	"864.0"	"1293.7"	"1176.9"	"840.3"	"1461.2"	"2609.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N684"	"Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1"	"17"	"7"	"13"	"7"	"471"	"52.0"	"8.00"	"2662.48"	"21.90"	"7"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"79869"	"ENSG00000149532"	"CPSF7"	"B3KU04; C9K0Q4; hsa:79869; Q7Z3H9; Q8N684; Q9H025; Q9H9V1"	""	"RHOBTB1 GTPase cycle; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"5"	"0"	"718.9"	"419.2"	"510.5"	"447.9"	"494.3"	"586.7"	"1312.1"	"1363.7"	"1015.5"	"1485.2"	"1947.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95218"	"Zinc finger Ran-binding domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ZRANB2 PE=1 SV=2"	"18"	"6"	"13"	"6"	"330"	"37.4"	"10.01"	"2119.21"	"21.88"	"5"	"6"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00641"	"9406"	"ENSG00000132485"	"ZRANB2"	"D3DQ75; hsa:9406; O95218; Q53GS3; Q59F92; Q5VV33; Q5VV34; Q8IXN6; Q9UP63"	""	""	"0"	"0"	"691.3"	"383.0"	"577.0"	"587.0"	"561.9"	"673.4"	"1873.1"	"1563.3"	"1085.9"	"1514.6"	"2118.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12004"	"Proliferating cell nuclear antigen OS=Homo sapiens OX=9606 GN=PCNA PE=1 SV=1"	"31"	"8"	"13"	"8"	"261"	"28.8"	"4.69"	"2206.90"	"21.84"	"6"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00705, Pf02747"	"5111"	"ENSG00000132646"	"PCNA"	"B2R897; D3DW02; hsa:5111; P12004"	"Cell cycle; Retinoblastoma gene in cancer; Primary focal segmental glomerulosclerosis (FSGS); Oxidative damage response; EGF/EGFR signaling pathway; G1 to S cell cycle control; DNA replication; Hepatitis B infection; Base excision repair; Nucleotide excision repair; 7q11.23 copy number variation syndrome; DNA repair pathways, full network; 16p11.2 proximal deletion syndrome; p53 transcriptional gene network; Nucleotide excision repair in xeroderma pigmentosum ; Urotensin-II-mediated signaling pathway; DNA mismatch repair; 10q11.21q11.23 copy number variation syndrome; A network map of Macrophage-stimulating protein (MSP) signaling"	"HDR through Homologous Recombination (HRR); E3 ubiquitin ligases ubiquitinate target proteins; SUMOylation of DNA replication proteins; Termination of translesion DNA synthesis; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; G1/S-Specific Transcription; Recognition of DNA damage by PCNA-containing replication complex; Transcription of E2F targets under negative control by DREAM complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Polymerase switching on the C-strand of the telomere; Polymerase switching; Removal of the Flap Intermediate; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"45"	"0"	"1096.1"	"754.5"	"1184.3"	"905.4"	"973.2"	"1135.7"	"1624.9"	"1454.0"	"1067.8"	"1712.2"	"2189.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19367"	"Hexokinase-1 OS=Homo sapiens OX=9606 GN=HK1 PE=1 SV=3"	"11"	"8"	"15"	"8"	"917"	"102.4"	"6.80"	"3396.51"	"21.83"	"7"	"7"	"other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;mitochondrion"	"kinase activity;other molecular function"	"Pf00349, Pf03727"	"3098"	"ENSG00000156515"	"HK1"	"E9PCK0; hsa:3098; O43443; O43444; O75574; P19367; Q5VTC3; Q96HC8; Q9NNZ4; Q9NNZ5"	"Cori cycle; Photodynamic therapy-induced HIF-1 survival signaling; Clear cell renal cell carcinoma pathways; Aerobic glycolysis; Disorders of fructose metabolism; Glucose metabolism in triple-negative breast cancer cells; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders; UDP-derived sugars synthesis in fibroblasts; Glucuronidation"	"Glycolysis; Defective HK1 causes hexokinase deficiency (HK deficiency)"	"12"	"0"	"703.1"	"322.3"	"466.1"	"654.1"	"541.8"	"686.8"	"968.7"	"930.9"	"730.7"	"995.6"	"1367.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P27635"	"60S ribosomal protein L10 OS=Homo sapiens OX=9606 GN=RPL10 PE=1 SV=4"	"24"	"6"	"13"	"6"	"214"	"24.6"	"10.08"	"2257.16"	"21.81"	"5"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00252"	"100137264; 100146244; 100172946; 100415355; 100468790; 100724614; 100982236; 101083663; 101136536; 101344695; 101444008; 101539056; 101690567; 101867181; 101975002; 102028809; 102257301; 102442647; 102878669; 102890423; 102923570; 102957760; 103127392; 103211225; 103250904; 103731218; 104667036; 104872587; 105294701; 105302495; 105467951; 105521640; 105579731; 105727260; 105824536; 105867804; 106000161; 107160308; 108513162; 108518769; 109696857; 110954; 465944; 700795; 81764"	"ENSAMEG00000000227; ENSANAG00000036053; ENSCAFG00020009114; ENSCAFG00030015144; ENSCAFG00040021422; ENSCAFG00845028627; ENSCANG00000032226; ENSCATG00000030970; ENSCCAG00000024992; ENSCGRG00001008387; ENSCJAG00000011822; ENSCLAG00000003108; ENSCPOG00000002355; ENSECAG00000017154; ENSFCAG00000011395; ENSGGOG00000000131; ENSLCNG00005021252; ENSMFAG00000040824; ENSMLUG00000014337; ENSMMMG00000014279; ENSMMUG00000005494; ENSMNEG00000038094; ENSMPUG00000009320; ENSMUSG00000008682; ENSMUSG00000058443; ENSNGAG00000023746; ENSNLEG00000028143; ENSNVIG00000023818; ENSPANG00000008309; ENSPCOG00000027122; ENSPPAG00000034160; ENSPPYG00000020874; ENSPSMG00000015404; ENSPTIG00000005599; ENSPTRG00000043378; ENSRBIG00000042996; ENSRNOG00000056765; ENSRROG00000019247; ENSSSUG00005010590; ENSSTOG00000011857; ENSTGEG00000012563; ENSUAMG00000020454; ENSUMAG00000019583; ENSUPAG00010000252"	"LOC100768740; LOC101344695; LOC105294701; LOC112632580; Rpl10; RPL10"	"A0A091D943; A0A1S3APJ4; A0A1S3GPT7; A0A1U7SU42; A0A250YCK6; A0A286XQR8; A0A2I3FV08; A0A2J8IN69; A0A2J8RLU6; A0A2K5EV78; A0A2K5ILK8; A0A2K5LLF2; A0A2K5QER4; A0A2K5U275; A0A2K6D043; A0A2K6GRP4; A0A2K6MTH0; A0A2K6NK39; A0A2R9B361; A0A2Y9G5G6; A0A384DKX1; A0A3Q0CF07; A0A3Q7NJC4; A0A452S2Z9; A0A485PEW4; A0A667IJV2; A0A673U4F8; A0A6D2WIN2; A0A6D2XTB8; A0A6I9ME29; A0A6J0A9X4; A0A6J2E7G1; A0A6J3GU06; A0A6P3QFP2; A0A6P5P1X6; A0A6P6DLY1; A0A7J7YFN8; A0A7J8J7V5; A0A822A0T4; A0A8B7B976; A0A8B7FW91; A0A8C0K7J7; A0A8C0TBM4; A0A8C2LMI8; A0A8C2UVN1; A0A8C5ZPE8; A0A8C6S1T7; A0A8C7BXJ2; A0A8C8ZPD3; A0A8C9J452; A0A8D2F5T2; A0A8D2GF85; A0A8I3PXJ3; A0A8J8XDM4; A0A8M1M1S6; A0A9B0U593; A2AM97; A6KRS1; A9CB60; aju:106987320; aml:100468790; B0KWW6; B1MTV1; B3RFD9; C3PT02; cang:105521640; caty:105579731; ccan:109696857; cpoc:100724614; csyr:103250904; D3YC00; dnm:101444008; dord:106000161; ecb:100146244; F7AYR2; F7GKJ8; fca:101083663; G1PPT9; G2HFW2; G3S9Q9; G7Q3B3; ggo:101136536; H2PX84; I2CYS4; I3MI39; L5KDV0; L8Y8T7; M3WF14; M3YD39; mcal:110286529; mcc:700795; mcf:101867181; mlf:102442647; mmu:110954; mmur:105867804; mni:105467951; mpuf:101690567; myb:102257301; nsu:110578606; P45634; pale:102878669; pale:102890423; panu:100137264; pcoq:105824536; pps:100982236; ptg:102957760; ptr:465944; pvp:105294701; pvp:105302495; Q569M8; Q5M9K8; Q6PDV7; Q6ZWV3; rbb:108513162; rbb:108518769; rno:81764; rro:104667036; S7NR49; sara:101539056; tmu:101344695; umr:103679662; zca:113931110"	"Cytoplasmic ribosomal proteins"	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; SRP-dependent cotranslational protein targeting to membrane; Major pathway of rRNA processing in the nucleolus and cytosol; L13a-mediated translational silencing of Ceruloplasmin expression; SRP-dependent cotranslational protein targeting to membrane; Major pathway of rRNA processing in the nucleolus and cytosol; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	"15"	"0"	"649.6"	"342.3"	"614.3"	"711.7"	"593.1"	"628.8"	"2047.3"	"1684.7"	"1060.0"	"1899.5"	"2386.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P37108"	"Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2"	"37"	"7"	"16"	"7"	"136"	"14.6"	"10.04"	"3342.10"	"21.61"	"6"	"5"	"transport"	"non-structural extracellular;cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02290"	"6727"	"ENSG00000140319"	"SRP14"	"B5BUF5; hsa:6727; P37108; Q6B0K5; Q96Q14"	""	"Neutrophil degranulation; SRP-dependent cotranslational protein targeting to membrane"	"2"	"0"	"305.7"	"239.3"	"296.3"	"297.9"	"299.7"	"301.4"	"2721.2"	"3679.3"	"4113.8"	"9873.5"	"14486.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96I24"	"Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2"	"13"	"7"	"14"	"5"	"572"	"61.6"	"8.38"	"1884.95"	"21.57"	"5"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"translational apparatus;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00013"	"8939"	"ENSG00000107164"	"FUBP3"	"A3KFK8; A3KFL0; hsa:8939; Q92946; Q96I24; Q9BVB6"	""	""	"0"	"0"	"486.5"	"319.6"	"406.3"	"298.8"	"415.2"	"433.1"	"641.3"	"501.2"	"388.7"	"728.0"	"882.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14644"	"Ras GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=RASA3 PE=1 SV=3"	"9"	"7"	"12"	"7"	"834"	"95.6"	"7.15"	"1705.63"	"21.53"	"5"	"7"	"transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol"	"transporter activity;enzyme regulator activity;other molecular function"	"Pf00168, Pf00169, Pf00616, Pf00779"	"22821"	"ENSG00000185989; ENSG00000280477"	"RASA3"	"A6NL15; F8W6X8; hsa:22821; Q14644; Q8IUY2"	"MAPK cascade; Ras signaling; IL-18 signaling pathway"	"Regulation of RAS by GAPs"	"4"	"0"	"255.2"	"206.0"	"292.5"	"312.6"	"352.3"	"406.9"	"980.5"	"848.6"	"669.7"	"1240.5"	"1662.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62851"	"40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1"	"38"	"6"	"17"	"6"	"125"	"13.7"	"10.11"	"2907.78"	"21.46"	"6"	"5"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf03297"	"6230"	"ENSG00000118181; ENSG00000280831"	"RPS25"	"B2R4M7; hsa:6230; P25111; P62851"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"664.1"	"490.1"	"513.3"	"465.5"	"508.6"	"579.2"	"1449.9"	"1417.0"	"1091.6"	"1489.8"	"1912.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P28066"	"Proteasome subunit alpha type-5 OS=Homo sapiens OX=9606 GN=PSMA5 PE=1 SV=3"	"29"	"5"	"11"	"5"	"241"	"26.4"	"4.79"	"1924.95"	"21.38"	"4"	"5"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf00227, Pf10584"	"5686"	"ENSG00000143106"	"PSMA5"	"B2R8F6; B4E2V4; hsa:5686; P28066; Q3T1C1; Q6IBF7"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"63"	"0"	"178.3"	"119.7"	"176.9"	"160.3"	"185.3"	"171.8"	"430.1"	"412.7"	"331.8"	"483.9"	"615.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IYB3"	"Serine/arginine repetitive matrix protein 1 OS=Homo sapiens OX=9606 GN=SRRM1 PE=1 SV=2"	"6"	"5"	"13"	"5"	"904"	"102.3"	"11.84"	"3709.96"	"21.36"	"5"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity"	"Pf01480"	"10250"	"ENSG00000133226"	"SRRM1"	"hsa:10250; O60585; Q5VVN4; Q8IYB3"	"mRNA processing"	"mRNA Splicing - Major Pathway; RHOBTB1 GTPase cycle; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; RHOBTB2 GTPase cycle"	"7"	"0"	"462.2"	"291.5"	"387.0"	"365.4"	"436.7"	"408.3"	"1544.1"	"1251.8"	"771.4"	"1305.3"	"1684.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08779"	"Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4"	"15"	"7"	"17"	"1"	"473"	"51.2"	"5.05"	"2938.57"	"21.35"	"7"	"5"	"cell organization and biogenesis;stress response;other biological processes"	"plasma membrane;cytosol;cytoskeleton"	"cytoskeletal activity"	"Pf00038"	"3868"	"ENSG00000186832"	"KRT16"	"A8K488; hsa:3868; P08779; P30654; Q16402; Q9UBG8"	"Vitamin D receptor pathway"	"Formation of the cornified envelope"	"3"	"0"	"5.7"	"2.1"	"4.4"	"8.3"	"6.0"	"2.9"	"12.5"	"13.8"	"6.0"	"13.8"	"542.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P02533"	"Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4"	"20"	"11"	"20"	"5"	"472"	"51.5"	"5.16"	"3710.74"	"21.03"	"10"	"7"	"cell organization and biogenesis;other biological processes"	"plasma membrane;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00038"	"3861"	"ENSG00000186847"	"KRT14"	"hsa:3861; P02533; Q14715; Q53XY3; Q9BUE3; Q9UBN2; Q9UBN3; Q9UCY4"	"Corticotropin-releasing hormone signaling pathway"	"Formation of the cornified envelope; Type I hemidesmosome assembly"	"4"	"3"	"499.8"	"286.5"	"4737.8"	"399.8"	"782.8"	"1016.1"	"1106.8"	"1064.9"	"802.2"	"1496.4"	"1450.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62834"	"Ras-related protein Rap-1A OS=Homo sapiens OX=9606 GN=RAP1A PE=1 SV=1"	"35"	"6"	"11"	"2"	"184"	"21.0"	"6.67"	"2368.54"	"20.95"	"5"	"6"	"cell-cell signaling;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00071"	"5906"	"ENSG00000116473"	"RAP1A"	"hsa:5906; P10113; P62834"	"Integrin-mediated cell adhesion; Thyroid stimulating hormone (TSH) signaling pathway; Androgen receptor network in prostate cancer; Brain-derived neurotrophic factor (BDNF) signaling pathway; Common pathways underlying drug addiction; Focal adhesion; Hepatocyte growth factor receptor signaling; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Ras signaling; EGF/EGFR signaling pathway; Leukocyte-intrinsic Hippo pathway functions; DNA repair pathways, full network; GDNF signaling; Interferon type I signaling pathways; Serotonin HTR1 group and FOS pathway; Serotonin receptor 4/6/7 and NR3C signaling"	"Neutrophil degranulation; Signaling by BRAF and RAF1 fusions; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; Rap1 signalling; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; Frs2-mediated activation; ARMS-mediated activation; GRB2:SOS provides linkage to MAPK signaling for Integrins ; p130Cas linkage to MAPK signaling for integrins; MET activates RAP1 and RAC1"	"34"	"4"	"454.8"	"276.1"	"349.2"	"273.3"	"316.8"	"373.4"	"885.4"	"902.5"	"667.1"	"954.8"	"991.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P16402"	"Histone H1.3 OS=Homo sapiens OX=9606 GN=H1-3 PE=1 SV=2"	"29"	"8"	"16"	"1"	"221"	"22.3"	"11.02"	"3234.96"	"20.77"	"8"	"6"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00538"	"3007"	"ENSG00000124575"	"H1-3"	"B2R751; hsa:3007; P16402; Q2M2I2"	""	"Formation of Senescence-Associated Heterochromatin Foci (SAHF); Apoptosis induced DNA fragmentation"	"2"	"0"	"24.4"	"14.0"	"15.0"	"7.8"	"17.6"	"15.8"	"60.1"	"60.4"	"43.5"	"64.9"	"81.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q2NL82"	"Pre-rRNA-processing protein TSR1 homolog OS=Homo sapiens OX=9606 GN=TSR1 PE=1 SV=1"	"15"	"9"	"14"	"9"	"804"	"91.8"	"7.42"	"2303.58"	"20.75"	"7"	"7"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04950, Pf08142"	"55720"	"ENSG00000167721"	"TSR1"	"hsa:55720; Q2NL82; Q8WUY5; Q9NVT0; Q9P2E6"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"438.3"	"217.0"	"367.0"	"321.0"	"381.8"	"311.3"	"871.7"	"793.0"	"496.8"	"840.6"	"1235.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95757"	"Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3"	"10"	"6"	"11"	"4"	"839"	"94.5"	"5.88"	"1754.49"	"20.64"	"4"	"6"	"protein metabolism;other metabolic processes;stress response"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00012"	"22824"	"ENSG00000164070"	"HSPA4L"	"A2ICT2; hsa:22824; O95757; Q4W5M5; Q8IWA2"	""	"Regulation of HSF1-mediated heat shock response"	"1"	"0"	"142.6"	"72.4"	"96.6"	"117.4"	"115.7"	"117.2"	"194.1"	"176.9"	"139.0"	"221.9"	"314.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62140"	"Serine/threonine-protein phosphatase PP1-beta catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CB PE=1 SV=3"	"25"	"6"	"10"	"1"	"327"	"37.2"	"6.19"	"1987.64"	"20.61"	"5"	"5"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00149, Pf16891"	"5500"	"ENSG00000213639"	"PPP1CB"	"B2R5V4; D6W565; hsa:5500; P37140; P62140; Q5U087; Q6FG45"	"Common pathways underlying drug addiction; Focal adhesion; Hippo-Merlin signaling dysregulation; 22q11.2 copy number variation syndrome; Airway smooth muscle cell contraction; Neuroinflammation and glutamatergic signaling; G13 signaling pathway"	"RHO GTPases activate CIT; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; Triglyceride catabolism; Regulation of PLK1 Activity at G2/M Transition; Circadian Clock; RAF activation; SHOC2 M1731 mutant abolishes MRAS complex function; Gain-of-function MRAS complexes activate RAF signaling; RHO GTPases activate PAKs; Downregulation of TGF-beta receptor signaling"	"18"	"0"	"130.1"	"65.9"	"102.5"	"157.9"	"117.4"	"108.5"	"454.7"	"353.7"	"179.6"	"332.2"	"482.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52434"	"DNA-directed RNA polymerases I, II, and III subunit RPABC3 OS=Homo sapiens OX=9606 GN=POLR2H PE=1 SV=4"	"37"	"6"	"15"	"6"	"150"	"17.1"	"4.68"	"2717.59"	"20.57"	"6"	"5"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf03870"	"5437"	"ENSG00000163882"	"POLR2H"	"C9J413; C9JBJ6; C9JCU7; C9JUA8; hsa:5437; P52434; P53802; Q969R0"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"mRNA Splicing - Major Pathway; Estrogen-dependent gene expression; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA; B-WICH complex positively regulates rRNA expression; RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; mRNA Splicing - Minor Pathway; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"57"	"0"	"238.3"	"143.0"	"193.1"	"202.8"	"181.5"	"232.2"	"477.8"	"679.0"	"783.4"	"1191.1"	"1663.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95400"	"CD2 antigen cytoplasmic tail-binding protein 2 OS=Homo sapiens OX=9606 GN=CD2BP2 PE=1 SV=1"	"27"	"6"	"10"	"6"	"341"	"37.6"	"4.61"	"1944.90"	"20.53"	"5"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf02213"	"10421"	"ENSG00000169217"	"CD2BP2"	"B2RDX2; hsa:10421; O95400; Q9ULP2"	"mRNA processing; Ciliary landscape"	""	"2"	"0"	"267.4"	"184.7"	"231.2"	"218.1"	"257.6"	"231.8"	"650.3"	"627.5"	"533.3"	"738.4"	"878.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43447"	"Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1"	"28"	"6"	"16"	"6"	"177"	"19.2"	"8.07"	"3627.55"	"20.50"	"6"	"6"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00160"	"10465"	"ENSG00000171960"	"PPIH"	"A6NNE7; hsa:10465; O43447"	""	"mRNA Splicing - Major Pathway; SARS-CoV-1 activates/modulates innate immune responses"	"2"	"0"	"840.3"	"504.4"	"736.2"	"739.9"	"790.6"	"755.3"	"1316.9"	"1202.1"	"912.4"	"1450.0"	"1921.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75663"	"TIP41-like protein OS=Homo sapiens OX=9606 GN=TIPRL PE=1 SV=2"	"25"	"5"	"10"	"5"	"272"	"31.4"	"5.91"	"1629.32"	"20.40"	"4"	"5"	"stress response;signal transduction;other biological processes"	"cytosol"	""	"Pf04176"	"261726"	"ENSG00000143155"	"TIPRL"	"B2R8V3; hsa:261726; O75663; Q5HYB2; Q8IZ86"	"Ciliary landscape"	""	"1"	"0"	"360.7"	"200.3"	"272.2"	"394.1"	"281.5"	"393.8"	"546.1"	"558.6"	"402.2"	"551.9"	"677.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63208"	"S-phase kinase-associated protein 1 OS=Homo sapiens OX=9606 GN=SKP1 PE=1 SV=2"	"31"	"6"	"11"	"6"	"163"	"18.6"	"4.54"	"2548.61"	"20.39"	"6"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf01466, Pf03931"	"6500"	"ENSG00000113558"	"SKP1"	"D3DQ97; D3DQ98; hsa:6500; P34991; P63208; Q8TAY2"	"Cell cycle; TNF-alpha signaling pathway; Breast cancer pathway; Small cell lung cancer; Notch signaling pathway"	"Antigen processing: Ubiquitination & Proteasome degradation; FCERI mediated NF-kB activation; Downstream TCR signaling; Activation of NF-kappaB in B cells; SCF-beta-TrCP mediated degradation of Emi1; Vpu mediated degradation of CD4; Degradation of beta-catenin by the destruction complex; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; NIK-->noncanonical NF-kB signaling; Orc1 removal from chromatin; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Neddylation; Regulation of PLK1 Activity at G2/M Transition; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; SCF(Skp2)-mediated degradation of p27/p21; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Circadian Clock; Cyclin D associated events in G1; Regulation of BACH1 activity; MAP3K8 (TPL2)-dependent MAPK1/3 activation; NOTCH1 Intracellular Domain Regulates Transcription; Prolactin receptor signaling; Iron uptake and transport; Nuclear events stimulated by ALK signaling in cancer; Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling"	"38"	"0"	"460.2"	"258.2"	"367.4"	"421.8"	"412.1"	"451.1"	"767.0"	"689.9"	"455.3"	"804.1"	"1162.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06493"	"Cyclin-dependent kinase 1 OS=Homo sapiens OX=9606 GN=CDK1 PE=1 SV=3"	"29"	"6"	"11"	"5"	"297"	"34.1"	"8.40"	"2663.61"	"20.35"	"6"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069"	"983"	"ENSG00000170312"	"CDK1"	"A8K7C4; C9J497; hsa:983; O60764; P06493"	"miRNA regulation of DNA damage response; Cell cycle; Microtubule cytoskeleton regulation; Spinal cord injury; Retinoblastoma gene in cancer; ATM signaling pathway; PPAR-alpha pathway; Nuclear receptors meta-pathway; ATM signaling in development and disease ; G1 to S cell cycle control; Cohesin complex - Cornelia de Lange syndrome; Urotensin-II-mediated signaling pathway; DNA damage response"	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A; MAPK6/MAPK4 signaling; The role of GTSE1 in G2/M progression after G2 checkpoint; Resolution of Sister Chromatid Cohesion; Recruitment of NuMA to mitotic centrosomes; Nuclear Pore Complex (NPC) Disassembly; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Regulation of TP53 Degradation; APC/C:Cdc20 mediated degradation of Cyclin B; Phosphorylation of the APC/C; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Transcriptional regulation by RUNX2; Ovarian tumor domain proteases; MASTL Facilitates Mitotic Progression; E2F-enabled inhibition of pre-replication complex formation; MAPK3 (ERK1) activation; Golgi Cisternae Pericentriolar Stack Reorganization; Condensation of Prophase Chromosomes; G1/S-Specific Transcription; Initiation of Nuclear Envelope (NE) Reformation; Condensation of Prometaphase Chromosomes; Activation of NIMA Kinases NEK9, NEK6, NEK7; G2/M DNA replication checkpoint; Depolymerization of the Nuclear Lamina; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1; Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes; Phosphorylation of Emi1"	"49"	"1"	"320.4"	"162.7"	"283.1"	"265.6"	"290.6"	"312.4"	"1044.6"	"1048.1"	"729.6"	"1087.9"	"1664.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15372"	"Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1"	"21"	"7"	"13"	"7"	"352"	"39.9"	"6.54"	"2577.47"	"20.30"	"7"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01398, Pf19445"	"8667"	"ENSG00000147677"	"EIF3H"	"hsa:8667; O15372"	"Translation factors; VEGFA-VEGFR2 signaling; Measles virus infection; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"10"	"0"	"659.8"	"389.1"	"664.0"	"486.0"	"631.1"	"537.9"	"1298.0"	"1115.0"	"767.1"	"1187.4"	"1596.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31483"	"Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3"	"17"	"7"	"14"	"4"	"386"	"42.9"	"7.74"	"2274.87"	"20.19"	"7"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"7072"	"ENSG00000116001"	"TIA1"	"hsa:7072; P31483; Q53SS9; Q96B58"	""	"FGFR2 alternative splicing"	"1"	"0"	"97.5"	"59.4"	"69.6"	"97.2"	"88.0"	"104.8"	"203.8"	"226.0"	"167.3"	"191.5"	"175.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13442"	"28 kDa heat- and acid-stable phosphoprotein OS=Homo sapiens OX=9606 GN=PDAP1 PE=1 SV=1"	"38"	"6"	"14"	"6"	"181"	"20.6"	"8.87"	"3361.00"	"20.12"	"6"	"5"	"signal transduction"	"non-structural extracellular;plasma membrane;other membranes;cytosol;other cell component"	""	"Pf10252"	"11333"	"ENSG00000106244"	"PDAP1"	"D6W5S5; hsa:11333; Q13442; Q92906"	""	"Neutrophil degranulation"	"1"	"0"	"684.7"	"431.1"	"589.9"	"546.0"	"577.4"	"540.9"	"2923.5"	"2596.5"	"1844.1"	"2291.1"	"2855.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P33993"	"DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4"	"11"	"7"	"13"	"7"	"719"	"81.3"	"6.46"	"2733.65"	"20.11"	"7"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855"	"4176"	"ENSG00000166508"	"MCM7"	"A4D2A1; A4D2A2; E9PGN9; hsa:4176; P33993; Q15076; Q96D34; Q96GL1"	"miRNA regulation of DNA damage response; Cell cycle; Retinoblastoma gene in cancer; Ciliary landscape; G1 to S cell cycle control; DNA replication"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"12"	"0"	"699.0"	"420.2"	"602.1"	"532.3"	"606.2"	"627.2"	"939.1"	"768.6"	"548.1"	"922.6"	"1333.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96SI9"	"Spermatid perinuclear RNA-binding protein OS=Homo sapiens OX=9606 GN=STRBP PE=1 SV=1"	"8"	"5"	"11"	"2"	"672"	"73.6"	"8.72"	"2478.99"	"20.09"	"5"	"4"	"other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity"	"Pf00035, Pf07528"	"55342"	"ENSG00000165209"	"STRBP"	"hsa:55342; Q32NB9; Q96SI9; Q9BUE1; Q9BXG4; Q9H0B4; Q9H7V1; Q9NUK4"	""	""	"0"	"0"	"122.7"	"53.4"	"98.7"	"76.2"	"95.2"	"106.7"	"231.0"	"202.0"	"124.9"	"243.9"	"395.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35659"	"Protein DEK OS=Homo sapiens OX=9606 GN=DEK PE=1 SV=1"	"17"	"6"	"12"	"6"	"375"	"42.6"	"8.56"	"1846.85"	"19.89"	"5"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytoskeleton;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf08766"	"7913"	"ENSG00000124795"	"DEK"	"B2R6K6; B4DN37; hsa:7913; P35659; Q5TGV4; Q5TGV5"	"IL-18 signaling pathway; 10q11.21q11.23 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; Transcriptional regulation of granulopoiesis; Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors"	"5"	"0"	"205.0"	"133.4"	"201.5"	"179.6"	"177.8"	"236.5"	"931.8"	"743.6"	"481.3"	"808.6"	"1142.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NQG5"	"Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1"	"21"	"6"	"12"	"4"	"326"	"36.9"	"5.97"	"2163.49"	"19.82"	"5"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf04818, Pf16566"	"58490"	"ENSG00000101413"	"RPRD1B"	"hsa:58490; Q1WDE7; Q6PKF4; Q9NQG5"	"Modulators of TCR signaling and T cell activation"	"RNA polymerase II transcribes snRNA genes"	"2"	"0"	"184.9"	"113.3"	"185.9"	"202.2"	"202.2"	"203.6"	"479.8"	"494.6"	"394.1"	"695.3"	"890.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43427"	"Acidic fibroblast growth factor intracellular-binding protein OS=Homo sapiens OX=9606 GN=FIBP PE=1 SV=3"	"18"	"7"	"13"	"7"	"364"	"41.9"	"6.48"	"2531.93"	"19.75"	"6"	"5"	"signal transduction"	"other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf05427"	"9158"	"ENSG00000172500"	"FIBP"	"A8K0J7; hsa:9158; O43427; Q27Q85; Q6IBQ3; Q9HD65"	"Modulators of TCR signaling and T cell activation"	""	"1"	"0"	"235.0"	"143.1"	"233.1"	"203.9"	"233.4"	"256.5"	"1227.2"	"2575.0"	"2462.4"	"4709.9"	"6640.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62277"	"40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2"	"30"	"7"	"16"	"7"	"151"	"17.2"	"10.54"	"2907.75"	"19.71"	"7"	"6"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00312, Pf08069"	"6207"	"ENSG00000110700"	"RPS13"	"B2R549; hsa:6207; P19116; P62277; Q02546; Q29200; Q498Y0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"1130.3"	"786.4"	"832.8"	"795.5"	"758.8"	"939.3"	"2399.7"	"2220.3"	"1740.7"	"2338.3"	"3226.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WYA6"	"Beta-catenin-like protein 1 OS=Homo sapiens OX=9606 GN=CTNNBL1 PE=1 SV=1"	"12"	"8"	"15"	"8"	"563"	"65.1"	"5.05"	"2711.99"	"19.69"	"7"	"7"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf08216"	"56259"	"ENSG00000132792"	"CTNNBL1"	"B4DE16; hsa:56259; Q0VAL9; Q0VAM0; Q53HI8; Q5JWZ2; Q5JWZ3; Q5JWZ7; Q5JWZ8; Q8N454; Q8NCL2; Q8TBD6; Q8WYA6; Q96KD2; Q9H7A5; Q9NQF9; Q9NTX0; Q9Y3M7"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"799.2"	"458.4"	"660.3"	"716.5"	"748.1"	"804.1"	"3151.0"	"2893.6"	"2122.0"	"3149.0"	"3907.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12972"	"Nuclear inhibitor of protein phosphatase 1 OS=Homo sapiens OX=9606 GN=PPP1R8 PE=1 SV=2"	"23"	"5"	"7"	"5"	"351"	"38.5"	"7.37"	"1155.80"	"19.67"	"3"	"4"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00498"	"5511"	"ENSG00000117751"	"PPP1R8"	"hsa:5511; Q12972; Q5TEJ2; Q5TEJ4; Q5TIF2; Q6PKF6; Q9UBH1; Q9UBZ0"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"382.1"	"161.9"	"268.9"	"262.3"	"273.3"	"300.3"	"518.7"	"481.5"	"381.1"	"563.7"	"861.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15056"	"Eukaryotic translation initiation factor 4H OS=Homo sapiens OX=9606 GN=EIF4H PE=1 SV=5"	"28"	"6"	"11"	"6"	"248"	"27.4"	"7.23"	"1786.10"	"19.58"	"5"	"6"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"7458"	"ENSG00000106682"	"EIF4H"	"A8K3R1; D3DXF6; D3DXF8; hsa:7458; Q15056"	"Translation factors; 7q11.23 copy number variation syndrome"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Translation initiation complex formation; Ribosomal scanning and start codon recognition"	"7"	"0"	"582.7"	"383.0"	"443.0"	"407.8"	"386.8"	"515.1"	"767.0"	"696.0"	"633.9"	"819.5"	"1165.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15185"	"Prostaglandin E synthase 3 OS=Homo sapiens OX=9606 GN=PTGES3 PE=1 SV=1"	"42"	"7"	"13"	"7"	"160"	"18.7"	"4.54"	"2887.09"	"19.50"	"7"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf04969"	"10728"	"ENSG00000110958"	"PTGES3"	"A8K7D0; B4DHP2; B4DP11; B4DP21; hsa:10728; Q15185; Q8WU70"	"Aryl hydrocarbon receptor pathway; Glucocorticoid receptor pathway; Nuclear receptors meta-pathway"	"Potential therapeutics for SARS; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Aryl hydrocarbon receptor signalling; Estrogen-dependent gene expression; Synthesis of Prostaglandins (PG) and Thromboxanes (TX); HSF1 activation; Attenuation phase"	"11"	"0"	"1408.8"	"829.8"	"1151.6"	"1041.6"	"1082.1"	"1120.8"	"2343.8"	"1868.4"	"1365.3"	"1713.8"	"2044.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P34896"	"Serine hydroxymethyltransferase, cytosolic OS=Homo sapiens OX=9606 GN=SHMT1 PE=1 SV=1"	"6"	"2"	"10"	"1"	"483"	"53.0"	"7.71"	"1930.92"	"19.48"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00464"	"6470"	"ENSG00000176974; ENSG00000284320"	"SHMT1"	"B4DPM9; D3DXD0; hsa:6470; P34896; Q96HY0; Q9UMD1; Q9UMD2"	"Glycine metabolism; Folate metabolism; One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways; Clear cell renal cell carcinoma pathways; Male infertility; Neuroinflammation and glutamatergic signaling; Metabolic Epileptic Disorders; Smith-Magenis and Potocki-Lupski syndrome copy number variation"	"Metabolism of folate and pterines; Carnitine synthesis"	"11"	"0"	"30.4"	"16.0"	"32.6"	"23.0"	"23.8"	"20.2"	"39.6"	"40.8"	"31.8"	"48.8"	"67.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62913"	"60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2"	"30"	"5"	"12"	"5"	"178"	"20.2"	"9.60"	"2150.14"	"19.42"	"4"	"4"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00281, Pf00673"	"6135"	"ENSG00000142676"	"RPL11"	"hsa:6135; P25121; P39026; P62913; Q8TDH2; Q9Y674"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"879.6"	"521.5"	"688.1"	"609.1"	"638.7"	"684.3"	"2547.1"	"2205.6"	"1386.7"	"2283.9"	"2885.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NYL9"	"Tropomodulin-3 OS=Homo sapiens OX=9606 GN=TMOD3 PE=1 SV=1"	"18"	"5"	"10"	"4"	"352"	"39.6"	"5.19"	"2014.30"	"19.34"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton"	"cytoskeletal activity"	"Pf03250"	"29766"	"ENSG00000138594"	"TMOD3"	"B2R6G7; hsa:29766; Q9NT43; Q9NYL9; Q9NZR0"	"VEGFA-VEGFR2 signaling"	"RND3 GTPase cycle; Striated Muscle Contraction; RHOBTB2 GTPase cycle"	"4"	"1"	"361.7"	"206.8"	"292.7"	"289.7"	"313.4"	"324.5"	"730.9"	"698.2"	"555.9"	"838.8"	"1073.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09972"	"Fructose-bisphosphate aldolase C OS=Homo sapiens OX=9606 GN=ALDOC PE=1 SV=2"	"14"	"7"	"13"	"1"	"364"	"39.4"	"6.87"	"2268.59"	"19.32"	"6"	"5"	"other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00274"	"230"	"ENSG00000109107"	"ALDOC"	"B2R5R3; hsa:230; P09972; Q3SYL3; Q6FH94; Q6P0L5"	"Clear cell renal cell carcinoma pathways; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"Neutrophil degranulation; Glycolysis; Gluconeogenesis"	"6"	"0"	"12.2"	"9.1"	"8.3"	"13.3"	"15.9"	"16.0"	"23.4"	"21.5"	"18.2"	"28.1"	"36.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBS4"	"DnaJ homolog subfamily B member 11 OS=Homo sapiens OX=9606 GN=DNAJB11 PE=1 SV=1"	"20"	"5"	"10"	"5"	"358"	"40.5"	"6.18"	"2045.57"	"19.28"	"4"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00226, Pf01556"	"51726"	"ENSG00000090520"	"DNAJB11"	"hsa:51726; Q542Y5; Q542Y9; Q6IAQ8; Q96JC6; Q9UBS4"	"Photodynamic therapy-induced unfolded protein response"	"XBP1(S) activates chaperone genes"	"2"	"0"	"542.4"	"381.8"	"621.1"	"589.1"	"571.8"	"636.7"	"531.1"	"482.9"	"377.4"	"626.1"	"960.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P258"	"Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2"	"16"	"8"	"15"	"8"	"522"	"56.0"	"8.78"	"2895.51"	"19.24"	"8"	"6"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00415"	"55920"	"ENSG00000179051; ENSG00000281540"	"RCC2"	"hsa:55920; Q8IVL9; Q9BSN6; Q9NPV8; Q9P258"	""	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"6"	"0"	"432.4"	"275.4"	"374.1"	"348.8"	"396.5"	"400.6"	"3551.9"	"2945.9"	"1411.7"	"1508.5"	"1956.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95433"	"Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1"	"23"	"7"	"12"	"7"	"338"	"38.3"	"5.53"	"1494.66"	"19.21"	"5"	"7"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi"	"other molecular function"	"Pf08327, Pf09229"	"10598"	"ENSG00000100591"	"AHSA1"	"B2R9L2; B4DUR9; hsa:10598; O95433; Q96IL6; Q9P060"	"T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection"	""	"1"	"0"	"1099.8"	"782.9"	"1212.3"	"962.3"	"1054.3"	"1030.5"	"1281.7"	"1296.7"	"1019.4"	"1458.4"	"2063.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NC96"	"Adaptin ear-binding coat-associated protein 1 OS=Homo sapiens OX=9606 GN=NECAP1 PE=1 SV=2"	"18"	"5"	"12"	"5"	"275"	"29.7"	"6.80"	"2075.00"	"19.16"	"4"	"5"	"transport"	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf07933"	"25977"	"ENSG00000089818"	"NECAP1"	"hsa:25977; Q2NL73; Q5XG95; Q6NWY6; Q8N153; Q8NC96; Q8NCB0; Q9BU52; Q9Y407"	""	"Cargo recognition for clathrin-mediated endocytosis; Golgi Associated Vesicle Biogenesis"	"3"	"0"	"172.9"	"107.7"	"157.9"	"174.6"	"195.1"	"203.2"	"626.8"	"1730.1"	"2705.0"	"5494.6"	"8244.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P83916"	"Chromobox protein homolog 1 OS=Homo sapiens OX=9606 GN=CBX1 PE=1 SV=1"	"29"	"4"	"10"	"3"	"185"	"21.4"	"4.93"	"2361.44"	"19.13"	"4"	"3"	"cell organization and biogenesis;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00385, Pf01393"	"10951"	"ENSG00000108468"	"CBX1"	"hsa:10951; P23197; P83916"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"HCMV Early Events"	"2"	"0"	"273.6"	"162.8"	"253.8"	"216.6"	"221.6"	"245.4"	"456.6"	"405.4"	"296.5"	"467.3"	"632.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P33240"	"Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1"	"15"	"6"	"11"	"6"	"577"	"60.9"	"6.83"	"1850.60"	"19.13"	"5"	"6"	"other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf14304, Pf14327"	"1478"	"ENSG00000101811"	"CSTF2"	"hsa:1478; P33240; Q5H951; Q6LA74; Q8N502"	"mRNA processing"	"tRNA processing in the nucleus; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"6"	"0"	"431.4"	"304.8"	"364.6"	"338.1"	"405.8"	"432.5"	"823.5"	"732.4"	"464.1"	"840.2"	"1144.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26196"	"Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2"	"14"	"7"	"13"	"6"	"483"	"54.4"	"8.66"	"2850.69"	"19.12"	"6"	"5"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"1656"	"ENSG00000110367"	"DDX6"	"hsa:1656; P26196; Q5D048"	""	"mRNA decay by 5' to 3' exoribonuclease"	"1"	"1"	"334.5"	"230.5"	"322.5"	"345.5"	"311.9"	"357.4"	"1237.4"	"1209.9"	"817.8"	"1338.0"	"1852.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13995"	"Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD2 PE=1 SV=2"	"16"	"6"	"14"	"6"	"350"	"37.9"	"8.73"	"2264.90"	"19.11"	"6"	"6"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00763, Pf02882"	"10797"	"ENSG00000065911"	"MTHFD2"	"hsa:10797; P13995; Q53G90; Q53GV5; Q53S36; Q7Z650"	"Folate metabolism; One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways"	"Metabolism of folate and pterines"	"4"	"0"	"786.0"	"460.0"	"626.7"	"666.9"	"706.4"	"768.4"	"1420.6"	"1436.3"	"1206.9"	"1522.5"	"1829.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13868"	"Exosome complex component RRP4 OS=Homo sapiens OX=9606 GN=EXOSC2 PE=1 SV=2"	"16"	"4"	"10"	"4"	"293"	"32.8"	"7.50"	"2117.59"	"19.10"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf14382, Pf15985"	"23404"	"ENSG00000130713"	"EXOSC2"	"A3KFL3; A3KFL4; B4DKK6; hsa:23404; Q13868; Q9NUY4"	"Ciliary landscape"	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	"7"	"0"	"223.4"	"156.2"	"243.4"	"195.7"	"208.3"	"242.6"	"485.6"	"475.8"	"355.6"	"577.7"	"831.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P16104"	"Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2"	"27"	"3"	"10"	"1"	"143"	"15.1"	"10.74"	"1195.87"	"19.10"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125, Pf16211"	"3014"	"ENSG00000188486"	"H2AX"	"hsa:3014; P16104; Q4ZGJ7; Q6IAS5"	"miRNA regulation of DNA damage response; miRNAs involved in DNA damage response; Proteasome degradation; ATM signaling in development and disease ; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; DNA repair pathways, full network; 5q35 copy number variation; DNA damage response"	"RUNX1 regulates transcription of genes involved in differentiation of HSCs; RMTs methylate histone arginines; Assembly of the ORC complex at the origin of replication; Amyloid fiber formation; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Oxidative Stress Induced Senescence; Senescence-Associated Secretory Phenotype (SASP); Processing of DNA double-strand break ends; Meiotic synapsis; Transcriptional regulation by small RNAs; Deposition of new CENPA-containing nucleosomes at the centromere; B-WICH complex positively regulates rRNA expression; Formation of the beta-catenin:TCF transactivating complex; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Pre-NOTCH Transcription and Translation; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; G2/M DNA damage checkpoint; RNA Polymerase I Promoter Escape; Meiotic recombination; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Packaging Of Telomere Ends; Condensation of Prophase Chromosomes; DNA Damage/Telomere Stress Induced Senescence; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; Nonhomologous End-Joining (NHEJ); RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	"46"	"0"	"19.1"	"16.6"	"23.4"	"18.3"	"25.4"	"29.0"	"112.7"	"102.7"	"75.9"	"117.2"	"111.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14978"	"Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2"	"10"	"8"	"13"	"8"	"699"	"73.6"	"9.47"	"2039.84"	"19.06"	"6"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05022"	"9221"	"ENSG00000166197"	"NOLC1"	"hsa:9221; Q14978; Q15030; Q5VV70; Q9BUV3"	""	""	"0"	"0"	"828.2"	"469.6"	"666.7"	"671.7"	"777.8"	"892.9"	"4596.9"	"3422.2"	"2099.9"	"2599.2"	"3665.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P40222"	"Alpha-taxilin OS=Homo sapiens OX=9606 GN=TXLNA PE=1 SV=3"	"18"	"7"	"12"	"6"	"546"	"61.9"	"6.52"	"2456.57"	"19.02"	"7"	"5"	"transport;other biological processes"	"non-structural extracellular;cytosol;other cell component"	"other molecular function"	"Pf09728"	"200081"	"ENSG00000084652"	"TXLNA"	"D3DPP6; hsa:200081; P40222; Q5TFJ6; Q66K62; Q86T54; Q86T85; Q86T86; Q86Y86; Q86YW3; Q8N2Y3"	""	"Other interleukin signaling"	"1"	"1"	"81.7"	"50.5"	"79.8"	"68.4"	"75.2"	"82.8"	"400.0"	"402.9"	"289.6"	"521.1"	"832.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P21127"	"Cyclin-dependent kinase 11B OS=Homo sapiens OX=9606 GN=CDK11B PE=1 SV=4"	"7"	"6"	"13"	"6"	"795"	"92.6"	"5.54"	"1907.82"	"19.01"	"5"	"6"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"984"	"ENSG00000248333"	"CDK11B"	"B7ZVY7; hsa:984; J3KTL7; J3QR29; J3QR44; O95265; P21127; Q12817; Q12818; Q12819; Q12820; Q12822; Q8N530; Q9NZS5; Q9UBJ0; Q9UBQ1; Q9UBR0; Q9UNY2; Q9UP57; Q9UP58; Q9UP59"	"1p36 copy number variation syndrome"	"Recruitment of mitotic centrosome proteins and complexes"	"2"	"0"	"316.5"	"199.7"	"312.3"	"253.4"	"294.5"	"336.7"	"749.1"	"676.7"	"467.1"	"805.4"	"1105.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14498"	"RNA-binding protein 39 OS=Homo sapiens OX=9606 GN=RBM39 PE=1 SV=2"	"9"	"5"	"13"	"5"	"530"	"59.3"	"10.10"	"1882.31"	"18.96"	"4"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00076, Pf15519"	"9584"	"ENSG00000131051"	"RBM39"	"A2RRD3; A5D8W2; B0BLV3; E1P5S0; E1P5S1; hsa:9584; Q14498; Q14499"	"VEGFA-VEGFR2 signaling; mRNA processing"	"mRNA Splicing - Major Pathway"	"3"	"0"	"583.3"	"399.8"	"477.4"	"485.3"	"495.2"	"582.4"	"909.1"	"782.8"	"572.0"	"1068.2"	"1336.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26358"	"DNA (cytosine-5)-methyltransferase 1 OS=Homo sapiens OX=9606 GN=DNMT1 PE=1 SV=2"	"6"	"7"	"12"	"7"	"1616"	"183.1"	"7.75"	"2191.27"	"18.96"	"6"	"6"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00145, Pf01426, Pf02008, Pf06464, Pf12047"	"1786"	"ENSG00000130816"	"DNMT1"	"A0AV63; B7ZLW6; hsa:1786; P26358; Q9UHG5; Q9ULA2; Q9UMZ6"	"Trans-sulfuration pathway; One-carbon metabolism; Retinoblastoma gene in cancer; Hematopoietic stem cell gene regulation by GABP alpha/beta complex; MTHFR deficiency"	"SUMOylation of DNA methylation proteins; NoRC negatively regulates rRNA expression; PRC2 methylates histones and DNA; Defective pyroptosis; DNA methylation"	"10"	"0"	"108.3"	"69.9"	"98.7"	"115.6"	"104.0"	"124.0"	"435.4"	"403.4"	"272.8"	"461.5"	"588.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30050"	"60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1"	"42"	"6"	"13"	"6"	"165"	"17.8"	"9.42"	"2601.83"	"18.95"	"6"	"5"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00298, Pf03946"	"6136"	"ENSG00000197958"	"RPL12"	"hsa:6136; P30050; Q5VVV2; Q6PB27"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"821.3"	"481.6"	"631.8"	"541.8"	"640.3"	"619.3"	"2408.9"	"2083.0"	"1357.4"	"2165.7"	"2728.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y697"	"Cysteine desulfurase, mitochondrial OS=Homo sapiens OX=9606 GN=NFS1 PE=1 SV=3"	"12"	"4"	"9"	"4"	"457"	"50.2"	"8.31"	"1968.93"	"18.90"	"3"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf00266"	"9054"	"ENSG00000244005"	"NFS1"	"B3KMA5; B4DXK9; E1P5R8; F5GYK5; hsa:9054; Q6P0L8; Q9NTZ5; Q9Y481; Q9Y697"	"Iron-sulfur cluster biogenesis"	""	"1"	"0"	"131.5"	"70.2"	"103.1"	"139.7"	"97.8"	"145.5"	"224.4"	"256.6"	"227.6"	"403.4"	"578.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09496"	"Clathrin light chain A OS=Homo sapiens OX=9606 GN=CLTA PE=1 SV=1"	"23"	"7"	"14"	"7"	"248"	"27.1"	"4.51"	"2101.66"	"18.89"	"7"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01086"	"1211"	"ENSG00000122705"	"CLTA"	"A8K4W3; B4DIN1; F5H6N3; hsa:1211; P09496; Q2XPN5; Q53XZ1"	"Synaptic vesicle pathway; Ebola virus infection in host; Fragile X syndrome"	"MHC class II antigen presentation; Recycling pathway of L1; Lysosome Vesicle Biogenesis; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; LDL clearance; Retrograde neurotrophin signalling; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation; Entry of Influenza Virion into Host Cell via Endocytosis; Formation of annular gap junctions"	"17"	"0"	"1578.4"	"1117.8"	"1477.5"	"1461.4"	"1548.5"	"1655.5"	"2202.5"	"2018.1"	"1450.2"	"2160.1"	"2869.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P016"	"Thymocyte nuclear protein 1 OS=Homo sapiens OX=9606 GN=THYN1 PE=1 SV=1"	"36"	"7"	"13"	"7"	"225"	"25.7"	"9.25"	"2495.97"	"18.88"	"7"	"6"	""	""	""	"Pf01878"	"29087"	"ENSG00000151500"	"THYN1"	"hsa:29087; Q567Q2; Q9H3L4; Q9HC20; Q9P016"	""	""	"0"	"0"	"208.1"	"151.8"	"209.5"	"253.8"	"232.7"	"282.3"	"968.4"	"909.1"	"639.1"	"992.0"	"1388.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P013"	"Spliceosome-associated protein CWC15 homolog OS=Homo sapiens OX=9606 GN=CWC15 PE=1 SV=2"	"27"	"5"	"9"	"5"	"229"	"26.6"	"5.71"	"1373.12"	"18.87"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity"	"Pf04889"	"51503"	"ENSG00000150316"	"CWC15"	"B2RC17; hsa:51503; Q05BV9; Q05DM1; Q9P013; Q9UI29"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"665.1"	"290.2"	"447.6"	"460.2"	"436.8"	"469.8"	"1186.3"	"969.3"	"702.6"	"1048.2"	"1604.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NQ29"	"Putative RNA-binding protein Luc7-like 1 OS=Homo sapiens OX=9606 GN=LUC7L PE=1 SV=1"	"12"	"5"	"11"	"2"	"371"	"43.7"	"9.92"	"1770.12"	"18.86"	"4"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03194"	"55692"	"ENSG00000007392"	"LUC7L"	"B8ZZ13; hsa:55692; Q96S32; Q9NPH4; Q9NQ29"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"151.0"	"113.4"	"123.5"	"118.7"	"141.9"	"148.2"	"385.1"	"375.2"	"262.5"	"410.4"	"475.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRP8"	"Partner of Y14 and mago OS=Homo sapiens OX=9606 GN=PYM1 PE=1 SV=1"	"30"	"4"	"10"	"4"	"204"	"22.6"	"9.45"	"1725.73"	"18.79"	"4"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity"	"Pf09282"	"84305"	"ENSG00000170473"	"PYM1"	"B6ZDM5; hsa:84305; Q8IXJ8; Q8N8E7; Q9BRP8"	"TAR syndrome"	""	"1"	"0"	"159.0"	"111.0"	"139.2"	"160.8"	"180.5"	"178.4"	"412.7"	"463.4"	"372.4"	"584.4"	"732.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35580"	"Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3"	"5"	"8"	"12"	"4"	"1976"	"228.9"	"5.54"	"1570.81"	"18.78"	"5"	"7"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00063, Pf00612, Pf01576, Pf02736"	"4628"	"ENSG00000133026"	"MYH10"	"B2RWP9; D3DTS1; F8VTL3; hsa:4628; P35580; Q12989; Q149N3; Q149N4; Q16087; Q4LE45; Q6PK16; Q9BWG0"	"Regulation of actin cytoskeleton"	"EPHA-mediated growth cone collapse; RHO GTPases activate PAKs; RHO GTPases activate CIT; Sema4D induced cell migration and growth-cone collapse; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs"	"7"	"1"	"167.5"	"115.6"	"168.8"	"144.8"	"185.8"	"197.7"	"375.3"	"345.4"	"265.9"	"440.7"	"583.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55196"	"Afadin OS=Homo sapiens OX=9606 GN=AFDN PE=1 SV=3"	"4"	"4"	"8"	"4"	"1824"	"206.7"	"6.47"	"1219.69"	"18.78"	"3"	"4"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00498, Pf00595, Pf00788, Pf01843"	"4301"	"ENSG00000130396"	"AFDN"	"hsa:4301; O75087; O75088; O75089; P55196; Q59FP0; Q5TIG6; Q5TIG7; Q9NSN7; Q9NU92"	"VEGFA-VEGFR2 signaling; Ras signaling; 1q21.1 copy number variation syndrome"	""	"3"	"0"	"76.4"	"55.1"	"68.8"	"64.7"	"68.3"	"73.7"	"241.5"	"250.4"	"239.1"	"535.8"	"1009.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08754"	"Guanine nucleotide-binding protein G(i) subunit alpha OS=Homo sapiens OX=9606 GN=GNAI3 PE=1 SV=3"	"13"	"5"	"14"	"3"	"354"	"40.5"	"5.69"	"2055.81"	"18.75"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00503"	"2773"	"ENSG00000065135"	"GNAI3"	"hsa:2773; P08754; P17539; Q5TZX1"	"Thyroid stimulating hormone (TSH) signaling pathway; S1P receptor signal transduction; Complement system; G protein signaling pathways; Chemokine signaling pathway; Hippo signaling regulation pathways; Purinergic signaling; Calcium regulation in cardiac cells; 5q35 copy number variation; Serotonin HTR1 group and FOS pathway"	"G alpha (i) signalling events; G alpha (z) signalling events; Adenylate cyclase inhibitory pathway; ADP signalling through P2Y purinoceptor 12; Extra-nuclear estrogen signaling; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production"	"18"	"1"	"1181.5"	"674.9"	"990.7"	"636.5"	"885.5"	"807.7"	"996.0"	"1031.5"	"867.6"	"1650.2"	"2385.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12931"	"Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3"	"12"	"8"	"15"	"7"	"704"	"80.1"	"8.21"	"2484.42"	"18.73"	"7"	"7"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00183, Pf02518"	"10131"	"ENSG00000126602"	"TRAP1"	"B4DR68; D3DUC8; F5H897; hsa:10131; O43642; O75235; Q12931; Q9UHL5"	"TNF-alpha signaling pathway; Clock-controlled autophagy in bone metabolism"	"Respiratory electron transport"	"3"	"0"	"680.4"	"357.9"	"435.7"	"698.0"	"616.7"	"876.4"	"890.7"	"900.2"	"669.3"	"1026.1"	"1604.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q04760"	"Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4"	"39"	"6"	"11"	"6"	"184"	"20.8"	"5.31"	"1982.89"	"18.66"	"5"	"6"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00903"	"2739"	"ENSG00000124767"	"GLO1"	"B2R6P7; B4DDV0; hsa:2739; P78375; Q04760; Q59EL0; Q5TZW3; Q96FC0; Q96J41"	""	"Pyruvate metabolism"	"1"	"0"	"558.5"	"453.5"	"538.5"	"318.5"	"424.8"	"479.0"	"527.7"	"469.2"	"441.5"	"1007.8"	"1756.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63279"	"SUMO-conjugating enzyme UBC9 OS=Homo sapiens OX=9606 GN=UBE2I PE=1 SV=1"	"28"	"6"	"10"	"6"	"158"	"18.0"	"8.66"	"2108.67"	"18.56"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00179"	"7329"	"ENSG00000103275"	"UBE2I"	"D3DU69; hsa:7329; P50550; P63279; Q15698; Q59GX1; Q86VB3"	"Androgen receptor signaling pathway; TAR syndrome"	"SUMOylation of RNA binding proteins; Formation of Incision Complex in GG-NER; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of DNA replication proteins; Postmitotic nuclear pore complex (NPC) reformation; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; Meiotic synapsis; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; SUMOylation of intracellular receptors; Processing of DNA double-strand break ends; Vitamin D (calciferol) metabolism; SUMOylation of transcription factors; Negative regulation of activity of TFAP2 (AP-2) family transcription factors; Maturation of nucleoprotein; SUMOylation of immune response proteins; SUMOylation of nuclear envelope proteins; Maturation of nucleoprotein; SUMO is transferred from E1 to E2 (UBE2I, UBC9)"	"25"	"0"	"647.7"	"330.3"	"557.2"	"613.4"	"534.1"	"647.6"	"1136.3"	"1162.7"	"943.4"	"1831.3"	"4510.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2Z4"	"Tyrosine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=YARS2 PE=1 SV=2"	"14"	"6"	"11"	"6"	"477"	"53.2"	"8.98"	"2230.68"	"18.56"	"6"	"5"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00579"	"51067"	"ENSG00000139131"	"YARS2"	"D3DUW8; hsa:51067; Q9H817; Q9Y2Z4"	"Orexin receptor pathway"	"Mitochondrial tRNA aminoacylation"	"2"	"0"	"393.1"	"187.0"	"385.6"	"304.8"	"310.1"	"356.3"	"981.6"	"857.0"	"824.7"	"1487.5"	"2082.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BW27"	"Nuclear pore complex protein Nup85 OS=Homo sapiens OX=9606 GN=NUP85 PE=1 SV=1"	"9"	"5"	"11"	"5"	"656"	"75.0"	"5.55"	"1737.17"	"18.49"	"4"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07575"	"79902"	"ENSG00000125450"	"NUP85"	"B4DMQ3; B4DPW1; hsa:79902; Q8NDI4; Q9BW27; Q9H9U1"	""	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; HCMV Late Events; HCMV Early Events; Transcriptional regulation by small RNAs; SARS-CoV-2 activates/modulates innate and adaptive immune responses; tRNA processing in the nucleus; Viral Messenger RNA Synthesis; SUMOylation of DNA damage response and repair proteins; Rev-mediated nuclear export of HIV RNA; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); Postmitotic nuclear pore complex (NPC) reformation"	"35"	"0"	"262.5"	"196.7"	"233.9"	"247.4"	"256.3"	"305.2"	"492.3"	"483.9"	"408.1"	"632.8"	"847.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62266"	"40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3"	"36"	"4"	"10"	"4"	"143"	"15.8"	"10.49"	"1729.37"	"18.46"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00164"	"6228"	"ENSG00000186468"	"RPS23"	"hsa:6228; P39028; P62266; Q6IB08"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of the ternary complex, and subsequently, the 43S complex; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"784.8"	"499.8"	"681.1"	"497.4"	"569.4"	"531.0"	"1762.0"	"1642.0"	"1206.8"	"1694.9"	"2253.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60508"	"Pre-mRNA-processing factor 17 OS=Homo sapiens OX=9606 GN=CDC40 PE=1 SV=1"	"12"	"6"	"11"	"6"	"579"	"65.5"	"7.06"	"1826.54"	"18.45"	"5"	"6"	"RNA metabolism OR transcription;other metabolic processes;developmental processes"	"nucleus"	"nucleic acid binding activity"	"Pf00400"	"51362"	"ENSG00000168438"	"CDC40"	"B2RBC5; hsa:51362; O60508; O75471; Q5SRN0; Q9UPG1"	"mRNA processing"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway"	"5"	"0"	"187.2"	"125.2"	"165.4"	"158.2"	"182.3"	"186.8"	"720.7"	"643.5"	"460.2"	"856.7"	"1281.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96KR1"	"Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2"	"6"	"5"	"10"	"5"	"1074"	"116.9"	"9.04"	"1835.25"	"18.44"	"5"	"5"	""	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf07528, Pf12874"	"51663"	"ENSG00000056097"	"ZFR"	"B2RNR5; hsa:51663; Q05C08; Q3B7X5; Q6P5A3; Q86UA0; Q96KR1; Q9H6V4; Q9NTI1; Q9Y687"	"Exercise-induced circadian regulation"	""	"1"	"0"	"131.7"	"117.6"	"142.7"	"143.2"	"175.3"	"177.1"	"475.8"	"419.2"	"305.1"	"473.2"	"535.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NYU2"	"UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3"	"5"	"6"	"11"	"6"	"1555"	"177.1"	"5.63"	"1711.56"	"18.40"	"5"	"6"	"protein metabolism;other metabolic processes;stress response"	"ER/Golgi;other cell component"	"other molecular function"	"Pf06427, Pf18400, Pf18401, Pf18402, Pf18403, Pf18404"	"56886"	"ENSG00000136731"	"UGGT1"	"hsa:56886; Q53QP2; Q53SL3; Q8IW30; Q9H8I4; Q9NYU2"	"IL-18 signaling pathway"	"ER Quality Control Compartment (ERQC)"	"2"	"0"	"188.5"	"107.0"	"143.2"	"179.6"	"156.0"	"170.7"	"338.5"	"400.7"	"250.2"	"458.5"	"461.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16181"	"Septin-7 OS=Homo sapiens OX=9606 GN=SEPTIN7 PE=1 SV=2"	"11"	"4"	"9"	"3"	"437"	"50.6"	"8.63"	"1582.41"	"18.33"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00735"	"989"	"ENSG00000122545"	"SEPTIN7"	"hsa:989; Q16181; Q52M76; Q6NX50"	""	"MAPK6/MAPK4 signaling"	"1"	"0"	"107.2"	"53.9"	"99.2"	"90.6"	"107.2"	"105.6"	"407.9"	"363.7"	"240.3"	"563.9"	"918.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63151"	"Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R2A PE=1 SV=1"	"17"	"6"	"12"	"6"	"447"	"51.7"	"6.20"	"1886.13"	"18.32"	"6"	"6"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity"	""	"5520"	"ENSG00000221914"	"PPP2R2A"	"B2RBU8; B4E1T7; hsa:5520; P50409; P63151; Q00007"	"Wnt signaling pathway and pluripotency; PI3K-Akt signaling pathway; Glycogen synthesis and degradation"	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Cyclin D associated events in G1; Cyclin A/B1/B2 associated events during G2/M transition; Initiation of Nuclear Envelope (NE) Reformation"	"7"	"0"	"110.1"	"64.8"	"120.0"	"93.7"	"117.8"	"105.4"	"170.3"	"172.5"	"124.8"	"186.8"	"255.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11387"	"DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2"	"9"	"6"	"12"	"6"	"765"	"90.7"	"9.31"	"1412.19"	"18.31"	"4"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf01028, Pf02919, Pf14370"	"7150"	"ENSG00000198900"	"TOP1"	"A8KA78; E1P5W3; hsa:7150; O43256; P11387; Q12855; Q12856; Q15610; Q5TFY3; Q9UJN0"	"Ebola virus infection in host; 15q25 copy number variation"	"SUMOylation of DNA replication proteins"	"3"	"0"	"219.3"	"114.1"	"168.5"	"168.9"	"200.8"	"209.6"	"507.9"	"524.0"	"434.3"	"838.1"	"1348.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62906"	"60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2"	"28"	"6"	"14"	"6"	"217"	"24.8"	"9.94"	"3181.75"	"18.16"	"5"	"5"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf00687"	"4736"	"ENSG00000198755"	"RPL10A"	"B2R801; hsa:4736; P52859; P53025; P62906; Q5TZT6; Q8J013"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"656.7"	"447.5"	"524.6"	"491.1"	"558.6"	"589.5"	"2015.1"	"1897.6"	"1222.8"	"2236.5"	"2605.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75494"	"Serine/arginine-rich splicing factor 10 OS=Homo sapiens OX=9606 GN=SRSF10 PE=1 SV=1"	"14"	"5"	"10"	"5"	"262"	"31.3"	"11.27"	"2015.25"	"18.15"	"5"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"10772"	"ENSG00000188529"	"SRSF10"	"A6NFM6; A6NI42; A6NIU7; B4DJP9; hsa:10772; O60572; O75494; Q5JRH9; Q5JRI0; Q5JRI2; Q5JRI3; Q5JRI4; Q96G09; Q96P17"	"mRNA processing"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"3"	"0"	"298.4"	"231.4"	"299.4"	"247.5"	"302.6"	"295.8"	"684.6"	"615.9"	"614.2"	"1301.5"	"1459.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y376"	"Calcium-binding protein 39 OS=Homo sapiens OX=9606 GN=CAB39 PE=1 SV=1"	"16"	"7"	"13"	"7"	"341"	"39.8"	"6.89"	"1839.86"	"18.12"	"6"	"6"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;other molecular function"	"Pf08569"	"51719"	"ENSG00000135932"	"CAB39"	"A8K8L7; hsa:51719; Q9Y376"	"AMP-activated protein kinase signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Endochondral ossification; Endochondral ossification with skeletal dysplasias"	"Neutrophil degranulation; Energy dependent regulation of mTOR by LKB1-AMPK"	"6"	"0"	"115.7"	"71.3"	"109.5"	"105.7"	"111.9"	"147.5"	"345.6"	"536.6"	"572.5"	"893.3"	"1283.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q07020"	"60S ribosomal protein L18 OS=Homo sapiens OX=9606 GN=RPL18 PE=1 SV=2"	"22"	"4"	"9"	"4"	"188"	"21.6"	"11.72"	"1488.79"	"18.11"	"3"	"4"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf17135"	"6141"	"ENSG00000063177"	"RPL18"	"F8VWC5; hsa:6141; Q07020; Q8WTZ6"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"595.3"	"431.0"	"510.8"	"482.2"	"513.3"	"557.9"	"1704.9"	"1459.4"	"997.5"	"1745.0"	"2299.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61224"	"Ras-related protein Rap-1b OS=Homo sapiens OX=9606 GN=RAP1B PE=1 SV=1"	"28"	"5"	"10"	"1"	"184"	"20.8"	"5.78"	"2465.84"	"17.99"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00071"	"5908"	"ENSG00000127314"	"RAP1B"	"B2R5Z2; B4DQI8; B4DW74; B4DW94; hsa:5908; P09526; P61224; Q502X3; Q5TZR4; Q6DCA1; Q6LES0"	"Integrin-mediated cell adhesion; Thyroid stimulating hormone (TSH) signaling pathway; Androgen receptor network in prostate cancer; Corticotropin-releasing hormone signaling pathway; Common pathways underlying drug addiction; Focal adhesion; Hepatocyte growth factor receptor signaling; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Ras signaling"	"Neutrophil degranulation; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Signaling by BRAF and RAF1 fusions; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; Rap1 signalling; GRB2:SOS provides linkage to MAPK signaling for Integrins ; p130Cas linkage to MAPK signaling for integrins; MET activates RAP1 and RAC1"	"25"	"0"	"18.2"	"5.4"	"10.6"	"4.2"	"11.2"	"15.8"	"36.0"	"34.6"	"27.3"	"50.2"	"55.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16352"	"Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2"	"10"	"5"	"15"	"3"	"499"	"55.4"	"5.40"	"2612.32"	"17.98"	"5"	"4"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00038, Pf04732"	"9118"	"ENSG00000148798"	"INA"	"B1AQK0; hsa:9118; Q16352; Q9BRC5"	""	""	"0"	"0"	"330.1"	"196.0"	"252.1"	"270.1"	"292.9"	"349.4"	"347.4"	"304.5"	"231.7"	"361.7"	"503.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P47813"	"Eukaryotic translation initiation factor 1A, X-chromosomal OS=Homo sapiens OX=9606 GN=EIF1AX PE=1 SV=2"	"47"	"5"	"10"	"5"	"144"	"16.5"	"5.24"	"1985.24"	"17.94"	"4"	"4"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf01176"	"1964"	"ENSG00000173674"	"EIF1AX"	"B2R5U5; hsa:1964; P47813; Q0VGC2; Q5JPS5; Q5JPS6"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition"	"8"	"0"	"571.1"	"318.4"	"466.9"	"480.3"	"460.6"	"473.4"	"963.3"	"867.9"	"629.0"	"1010.6"	"1426.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60900"	"Proteasome subunit alpha type-6 OS=Homo sapiens OX=9606 GN=PSMA6 PE=1 SV=1"	"33"	"7"	"12"	"7"	"246"	"27.4"	"6.76"	"2092.18"	"17.93"	"6"	"6"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00227, Pf10584"	"5687"	"ENSG00000100902"	"PSMA6"	"B2R7J9; B4DQR4; B4DXJ9; hsa:5687; P34062; P60900; Q6IB60"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"ABC-family proteins mediated transport; Separation of Sister Chromatids; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"62"	"0"	"159.4"	"127.8"	"159.6"	"153.0"	"170.8"	"194.3"	"424.4"	"424.3"	"361.0"	"524.9"	"638.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2L1"	"Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2"	"8"	"6"	"11"	"6"	"958"	"108.9"	"7.14"	"2404.93"	"17.88"	"6"	"5"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00773, Pf13638, Pf17215, Pf17216, Pf17849"	"22894"	"ENSG00000083520"	"DIS3"	"A6NI21; B2RBL2; hsa:22894; Q5W0P7; Q5W0P8; Q658Z7; Q7Z481; Q8WWI2; Q9UG36; Q9Y2L1"	""	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	"6"	"0"	"483.8"	"326.9"	"480.2"	"436.8"	"505.4"	"566.1"	"933.5"	"950.5"	"707.3"	"1019.7"	"1378.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NUP9"	"Protein lin-7 homolog C OS=Homo sapiens OX=9606 GN=LIN7C PE=1 SV=1"	"25"	"6"	"13"	"5"	"197"	"21.8"	"8.43"	"1954.07"	"17.88"	"5"	"6"	"cell-cell signaling;transport;other biological processes"	"plasma membrane;other membranes;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00595, Pf02828"	"55327"	"ENSG00000148943"	"LIN7C"	"hsa:55327; Q9NUP9"	""	"Neurexins and neuroligins; Assembly and cell surface presentation of NMDA receptors; Dopamine Neurotransmitter Release Cycle"	"3"	"1"	"702.2"	"424.8"	"556.9"	"567.4"	"568.1"	"718.6"	"1303.0"	"1347.5"	"1084.5"	"1535.5"	"2082.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75934"	"Pre-mRNA-splicing factor SPF27 OS=Homo sapiens OX=9606 GN=BCAS2 PE=1 SV=1"	"21"	"4"	"8"	"4"	"225"	"26.1"	"5.66"	"1828.44"	"17.85"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"cytoskeleton;nucleus;other cell component"	""	"Pf05700"	"10286"	"ENSG00000116752"	"BCAS2"	"hsa:10286; O75934; Q6FGS0"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"209.6"	"158.4"	"243.4"	"197.2"	"195.1"	"250.9"	"652.8"	"675.4"	"478.2"	"824.2"	"1143.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62995"	"Transformer-2 protein homolog beta OS=Homo sapiens OX=9606 GN=TRA2B PE=1 SV=1"	"18"	"6"	"13"	"5"	"288"	"33.6"	"11.25"	"2180.14"	"17.81"	"6"	"5"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6434"	"ENSG00000136527"	"TRA2B"	"B4DVK2; D3DNU3; hsa:6434; O15449; P62995; Q15815; Q64283"	"mRNA processing"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle"	"5"	"0"	"280.7"	"178.2"	"226.6"	"191.9"	"224.6"	"259.3"	"509.7"	"467.9"	"652.1"	"1377.4"	"1858.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62750"	"60S ribosomal protein L23a OS=Homo sapiens OX=9606 GN=RPL23A PE=1 SV=1"	"37"	"7"	"14"	"7"	"156"	"17.7"	"10.45"	"2824.52"	"17.78"	"7"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00276, Pf03939"	"6147"	"ENSG00000198242"	"RPL23A"	"B2R5B2; hsa:6147; P29316; P39024; P62750; Q92774"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"498.3"	"336.8"	"471.6"	"389.9"	"507.6"	"472.2"	"2053.6"	"1922.4"	"1323.1"	"2159.2"	"2257.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13123"	"Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3"	"11"	"8"	"13"	"8"	"557"	"65.6"	"6.64"	"2514.39"	"17.77"	"7"	"6"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07807, Pf07808"	"3550"	"ENSG00000113141"	"IK"	"hsa:3550; Q13123; Q6IPD8"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"547.1"	"337.0"	"419.9"	"416.6"	"437.8"	"513.2"	"1469.1"	"1346.9"	"1075.6"	"1651.4"	"2264.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20962"	"Parathymosin OS=Homo sapiens OX=9606 GN=PTMS PE=1 SV=2"	"29"	"4"	"11"	"4"	"102"	"11.5"	"4.16"	"2308.34"	"17.70"	"4"	"3"	"DNA metabolism;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf03247"	"5763"	"ENSG00000159335"	"PTMS"	"hsa:5763; P20962"	"IL-18 signaling pathway"	""	"1"	"0"	"875.3"	"357.7"	"656.4"	"566.3"	"632.2"	"578.9"	"1051.2"	"907.6"	"622.2"	"870.4"	"1269.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13112"	"Chromatin assembly factor 1 subunit B OS=Homo sapiens OX=9606 GN=CHAF1B PE=1 SV=1"	"13"	"5"	"11"	"5"	"559"	"61.5"	"7.50"	"1510.59"	"17.69"	"4"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf00400, Pf15512"	"8208"	"ENSG00000159259"	"CHAF1B"	"hsa:8208; Q13112; Q99548"	""	""	"0"	"0"	"43.1"	"27.7"	"44.2"	"54.7"	"45.0"	"43.0"	"120.2"	"126.5"	"100.2"	"134.5"	"195.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15287"	"RNA-binding protein with serine-rich domain 1 OS=Homo sapiens OX=9606 GN=RNPS1 PE=1 SV=1"	"16"	"5"	"10"	"5"	"305"	"34.2"	"11.84"	"1690.24"	"17.69"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"10921"	"ENSG00000205937"	"RNPS1"	"A8K1P0; B4DDU8; B4DZU7; B7ZA17; hsa:10921; O75308; Q15287; Q32P25; Q8WY42; Q9NYG3"	"mRNA processing"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"7"	"0"	"259.4"	"182.1"	"238.2"	"190.2"	"247.5"	"264.6"	"545.2"	"475.1"	"523.3"	"1174.8"	"1506.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60828"	"Polyglutamine-binding protein 1 OS=Homo sapiens OX=9606 GN=PQBP1 PE=1 SV=1"	"23"	"4"	"7"	"4"	"265"	"30.5"	"6.33"	"1415.51"	"17.64"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	""	"10084"	"ENSG00000102103"	"PQBP1"	"C9JQA1; hsa:10084; O60828; Q4VY25; Q4VY26; Q4VY27; Q4VY29; Q4VY30; Q4VY34; Q4VY35; Q4VY36; Q4VY37; Q4VY38; Q9GZP2; Q9GZU4; Q9GZZ4"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"418.0"	"233.8"	"336.3"	"296.6"	"314.1"	"316.5"	"761.3"	"673.6"	"531.9"	"723.1"	"1010.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60660"	"Myosin light polypeptide 6 OS=Homo sapiens OX=9606 GN=MYL6 PE=1 SV=2"	"30"	"4"	"10"	"4"	"151"	"16.9"	"4.65"	"1856.93"	"17.36"	"4"	"4"	"other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	""	"4637"	"ENSG00000092841"	"MYL6"	"hsa:4637; P16475; P24572; P24573; P60660; Q12790; Q561V9; Q6IAZ0; Q6IPY5"	"Ciliary landscape"	"RHO GTPases activate CIT; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; Smooth Muscle Contraction; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; RHO GTPases activate PAKs"	"8"	"0"	"331.3"	"197.8"	"291.9"	"252.2"	"280.0"	"309.5"	"725.2"	"713.1"	"576.0"	"934.3"	"1131.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04908"	"Histone H2A type 1-B/E OS=Homo sapiens OX=9606 GN=H2AC4 PE=1 SV=2"	"27"	"3"	"11"	"1"	"130"	"14.1"	"11.05"	"1495.70"	"17.34"	"3"	"3"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125, Pf16211"	"3012; 8335"	"ENSG00000277075; ENSG00000278463"	"H2AC4; H2AC8"	"hsa:3012; hsa:8335; P04908; P28001; Q76P63"	"Proteasome degradation"	"Deposition of new CENPA-containing nucleosomes at the centromere; B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; Amyloid fiber formation; Meiotic synapsis; HCMV Late Events; UCH proteinases; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; HCMV Early Events; Transcriptional regulation by small RNAs; Formation of the beta-catenin:TCF transactivating complex; Oxidative Stress Induced Senescence; HDACs deacetylate histones; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Metalloprotease DUBs; Pre-NOTCH Transcription and Translation; Senescence-Associated Secretory Phenotype (SASP); RMTs methylate histone arginines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; HATs acetylate histones; RNA Polymerase I Promoter Escape; Meiotic recombination; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Packaging Of Telomere Ends; Condensation of Prophase Chromosomes; DNA Damage/Telomere Stress Induced Senescence; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	"42"	"2"	"882.9"	"453.3"	"652.7"	"567.7"	"661.9"	"599.4"	"3311.2"	"2846.4"	"1764.1"	"3127.2"	"3691.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01130"	"Serine/arginine-rich splicing factor 2 OS=Homo sapiens OX=9606 GN=SRSF2 PE=1 SV=4"	"15"	"3"	"9"	"3"	"221"	"25.5"	"11.85"	"1880.42"	"17.30"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00076"	"6427"	"ENSG00000161547"	"SRSF2"	"B3KWD5; B4DN89; H0YG49; hsa:6427; Q01130"	"mRNA processing"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Minor Pathway"	"7"	"0"	"477.1"	"394.7"	"438.8"	"418.1"	"427.0"	"513.9"	"1419.6"	"1101.3"	"716.0"	"827.9"	"741.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y230"	"RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3"	"13"	"6"	"12"	"6"	"463"	"51.1"	"5.64"	"1897.65"	"17.30"	"6"	"6"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06068, Pf17856"	"10856"	"ENSG00000183207"	"RUVBL2"	"B3KQ59; E7ETE5; hsa:10856; Q6FIB9; Q6PK27; Q9Y230; Q9Y361"	""	"Telomere Extension By Telomerase; HATs acetylate histones"	"2"	"0"	"457.6"	"274.6"	"356.0"	"295.7"	"373.7"	"378.4"	"598.8"	"519.3"	"374.7"	"697.8"	"873.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P0C7P4"	"Putative cytochrome b-c1 complex subunit Rieske-like protein 1 OS=Homo sapiens OX=9606 GN=UQCRFS1P1 PE=5 SV=1"	"27"	"7"	"10"	"7"	"283"	"30.8"	"8.87"	"1269.49"	"16.99"	"4"	"6"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00355, Pf02921, Pf09165"	""	""	"UQCRFS1P1"	"P0C7P4"	""	""	"0"	"0"	"1123.4"	"521.7"	"754.1"	"925.3"	"831.1"	"1016.5"	"1711.7"	"1674.2"	"1287.6"	"2059.2"	"3352.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRG1"	"Vacuolar protein-sorting-associated protein 25 OS=Homo sapiens OX=9606 GN=VPS25 PE=1 SV=1"	"34"	"5"	"11"	"5"	"176"	"20.7"	"6.34"	"2076.35"	"16.99"	"5"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf05871"	"84313"	"ENSG00000131475"	"VPS25"	"B2R581; hsa:84313; Q9BRG1"	""	"Endosomal Sorting Complex Required For Transport (ESCRT); HCMV Late Events"	"2"	"0"	"117.7"	"90.3"	"129.8"	"124.9"	"137.1"	"157.2"	"281.3"	"434.0"	"428.4"	"868.3"	"1828.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62841"	"40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2"	"23"	"2"	"8"	"2"	"145"	"17.0"	"10.39"	"1479.50"	"16.95"	"1"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00203"	"6209"	"ENSG00000115268"	"RPS15"	"A5D8V9; hsa:6209; P11174; P62841; Q3KRA1; Q9UDC2"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; SRP-dependent cotranslational protein targeting to membrane; SARS-CoV-2 modulates host translation machinery; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"297.9"	"194.0"	"266.1"	"201.3"	"256.1"	"258.0"	"920.4"	"826.3"	"573.2"	"791.3"	"1091.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQ39"	"ATP-dependent RNA helicase DDX50 OS=Homo sapiens OX=9606 GN=DDX50 PE=1 SV=1"	"8"	"5"	"9"	"3"	"737"	"82.5"	"9.17"	"1617.85"	"16.94"	"4"	"5"	""	"plasma membrane;other membranes;nucleus"	"other molecular function"	"Pf00270, Pf00271, Pf08152"	"79009"	"ENSG00000107625"	"DDX50"	"hsa:79009; Q5VX37; Q8WV76; Q9BQ39; Q9BWI8"	""	""	"0"	"0"	"78.9"	"76.5"	"81.9"	"70.0"	"88.6"	"105.0"	"174.6"	"181.1"	"123.8"	"226.3"	"238.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P32322"	"Pyrroline-5-carboxylate reductase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PYCR1 PE=1 SV=2"	"20"	"4"	"11"	"3"	"319"	"33.3"	"7.61"	"1723.70"	"16.82"	"3"	"4"	"other metabolic processes;stress response;other biological processes"	"mitochondrion"	"other molecular function"	"Pf03807, Pf14748"	"5831"	"ENSG00000183010"	"PYCR1"	"A6NFM2; B4DMU0; hsa:5831; P32322; Q6FHI4; Q96DI6; Q9HBQ4"	"Amino acid metabolism; Metabolic reprogramming in colon cancer"	"Glutamate and glutamine metabolism"	"3"	"1"	"193.5"	"125.3"	"172.9"	"141.2"	"159.9"	"166.6"	"346.8"	"307.0"	"233.4"	"382.4"	"459.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L2H7"	"Eukaryotic translation initiation factor 3 subunit M OS=Homo sapiens OX=9606 GN=EIF3M PE=1 SV=1"	"16"	"5"	"9"	"5"	"374"	"42.5"	"5.63"	"1380.97"	"16.80"	"4"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01399, Pf18005"	"10480"	"ENSG00000149100"	"EIF3M"	"A8K7X4; B4E2Q4; hsa:10480; O60735; Q2F836; Q53HL6; Q7L2H7; Q9BXW1"	""	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"6"	"0"	"115.4"	"104.6"	"180.1"	"119.6"	"163.6"	"133.2"	"263.8"	"245.1"	"169.6"	"278.7"	"369.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46783"	"40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1"	"37"	"7"	"19"	"6"	"165"	"18.9"	"10.15"	"4030.37"	"16.79"	"6"	"4"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf03501"	"6204"	"ENSG00000124614"	"RPS10"	"B2R4E3; hsa:6204; P46783; Q5TZC0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"1211.3"	"796.5"	"1059.5"	"920.3"	"1062.7"	"940.8"	"3240.5"	"3077.7"	"2465.5"	"3292.5"	"3715.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15007"	"Pre-mRNA-splicing regulator WTAP OS=Homo sapiens OX=9606 GN=WTAP PE=1 SV=2"	"12"	"3"	"8"	"3"	"396"	"44.2"	"5.19"	"1592.25"	"16.77"	"3"	"3"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf17098"	"9589"	"ENSG00000146457"	"WTAP"	"hsa:9589; Q15007; Q5TCL8; Q5TCL9; Q96T28; Q9BYJ7; Q9H4E2"	""	"Processing of Capped Intron-Containing Pre-mRNA"	"1"	"0"	"95.4"	"67.7"	"109.0"	"80.5"	"100.4"	"117.9"	"175.5"	"156.0"	"105.5"	"207.4"	"248.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23921"	"Ribonucleoside-diphosphate reductase large subunit OS=Homo sapiens OX=9606 GN=RRM1 PE=1 SV=1"	"8"	"5"	"9"	"5"	"792"	"90.0"	"7.15"	"1472.07"	"16.75"	"4"	"5"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf00317, Pf02867, Pf03477"	"6240"	"ENSG00000167325"	"RRM1"	"hsa:6240; P23921; Q9UNN2"	"Fluoropyrimidine activity; Retinoblastoma gene in cancer; Pyrimidine metabolism"	"Interconversion of nucleotide di- and triphosphates"	"4"	"0"	"317.0"	"141.0"	"215.4"	"276.6"	"257.4"	"254.5"	"495.4"	"454.3"	"308.2"	"595.7"	"1120.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46060"	"Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1"	"13"	"7"	"15"	"7"	"587"	"63.5"	"4.68"	"2538.56"	"16.67"	"7"	"5"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf07834, Pf13516"	"5905"	"ENSG00000100401"	"RANGAP1"	"hsa:5905; P46060; Q96JJ2"	"22q11.2 copy number variation syndrome; IL-18 signaling pathway"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Rev-mediated nuclear export of HIV RNA; SUMOylation of DNA replication proteins; Postmitotic nuclear pore complex (NPC) reformation; SUMOylation of nuclear envelope proteins"	"12"	"0"	"365.5"	"228.4"	"294.6"	"301.7"	"267.7"	"351.8"	"688.5"	"665.2"	"477.8"	"693.0"	"938.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52298"	"Nuclear cap-binding protein subunit 2 OS=Homo sapiens OX=9606 GN=NCBP2 PE=1 SV=1"	"31"	"5"	"9"	"5"	"156"	"18.0"	"8.21"	"1433.80"	"16.63"	"4"	"5"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"22916"	"ENSG00000114503"	"NCBP2"	"B2RE91; B4DMK7; E9PAR5; hsa:22916; P52298; Q14924; Q2TS50"	"mRNA processing; 3q29 copy number variation syndrome"	"mRNA Splicing - Major Pathway; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Abortive elongation of HIV-1 transcript in the absence of Tat; RNA Polymerase II Pre-transcription Events; RNA polymerase II transcribes snRNA genes; mRNA Capping; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Signaling by FGFR2 IIIa TM; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; snRNP Assembly; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"29"	"0"	"465.6"	"317.2"	"449.4"	"407.4"	"406.6"	"460.1"	"966.7"	"867.8"	"571.7"	"1136.3"	"1601.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NSB2"	"Keratin, type II cuticular Hb4 OS=Homo sapiens OX=9606 GN=KRT84 PE=2 SV=2"	"9"	"5"	"10"	"2"	"600"	"64.8"	"7.56"	"1374.75"	"16.58"	"4"	"5"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton"	"bone, tooth or skin structural activity;cytoskeletal activity"	"Pf00038, Pf16208"	"3890"	"ENSG00000161849"	"KRT84"	"B2RA43; hsa:3890; Q6ISB0; Q701L6; Q9NSB2"	""	"Formation of the cornified envelope"	"2"	"0"	"27.3"	"14.9"	"42.3"	"27.1"	"506.4"	"32.0"	"34.5"	"48.1"	"38.0"	"61.2"	"75.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13011"	"Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial OS=Homo sapiens OX=9606 GN=ECH1 PE=1 SV=2"	"14"	"5"	"9"	"5"	"328"	"35.8"	"8.00"	"1429.23"	"16.53"	"4"	"5"	"other metabolic processes"	"cytosol;mitochondrion;other cytoplasmic organelle"	"other molecular function"	"Pf00378"	"1891"	"ENSG00000104823; ENSG00000282853"	"ECH1"	"A8K745; hsa:1891; Q13011; Q8WVX0; Q96EZ9"	"Fatty acid biosynthesis; IL-18 signaling pathway"	"Peroxisomal protein import"	"3"	"0"	"305.2"	"198.4"	"263.2"	"247.3"	"315.6"	"267.0"	"623.9"	"722.8"	"619.6"	"1111.5"	"1902.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P32929"	"Cystathionine gamma-lyase OS=Homo sapiens OX=9606 GN=CTH PE=1 SV=3"	"13"	"4"	"10"	"4"	"405"	"44.5"	"6.70"	"1731.93"	"16.50"	"4"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf01053"	"1491"	"ENSG00000116761"	"CTH"	"B4E1R2; E9PDV0; hsa:1491; P32929; Q53FB3; Q53Y79; Q9H4W7; Q9H4W8"	"Selenium micronutrient network; Vitamin B12 metabolism; Folate metabolism; Trans-sulfuration pathway; Trans-sulfuration, one-carbon metabolism and related pathways; Amino acid metabolism; Methionine metabolism leading to sulfur amino acids and related disorders; Ferroptosis"	"Degradation of cysteine and homocysteine; Metabolism of ingested SeMet, Sec, MeSec into H2Se; Cysteine formation from homocysteine"	"11"	"0"	"97.6"	"77.2"	"113.6"	"96.7"	"105.1"	"118.8"	"205.7"	"188.1"	"138.7"	"235.0"	"299.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61964"	"WD repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=WDR5 PE=1 SV=1"	"15"	"5"	"10"	"5"	"334"	"36.6"	"8.27"	"1491.41"	"16.48"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00400"	"11091"	"ENSG00000196363"	"WDR5"	"hsa:11091; P61964; Q91VA5; Q9NWX7; Q9UGP9"	"Pleural mesothelioma; Kleefstra syndrome"	"Neddylation; Activation of anterior HOX genes in hindbrain development during early embryogenesis; PKMTs methylate histone lysines; Formation of WDR5-containing histone-modifying complexes; RMTs methylate histone arginines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; HATs acetylate histones; Cardiogenesis"	"10"	"0"	"316.2"	"182.7"	"370.1"	"292.9"	"327.6"	"306.1"	"911.1"	"905.2"	"680.3"	"1199.2"	"1678.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49207"	"60S ribosomal protein L34 OS=Homo sapiens OX=9606 GN=RPL34 PE=1 SV=3"	"29"	"5"	"14"	"5"	"117"	"13.3"	"11.47"	"2580.97"	"16.45"	"5"	"4"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01199"	"6164"	"ENSG00000109475"	"RPL34"	"hsa:6164; P49207; Q6FG66; Q9BUZ2"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"555.4"	"414.8"	"514.8"	"455.1"	"533.9"	"526.3"	"1878.4"	"1726.3"	"1233.5"	"1875.3"	"1993.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00303"	"Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1"	"15"	"5"	"12"	"5"	"357"	"37.5"	"5.45"	"1971.91"	"16.43"	"5"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01398, Pf13012"	"8665"	"ENSG00000175390"	"EIF3F"	"A8K0S2; hsa:8665; O00303; Q6IB45; Q8N978"	"Translation factors; VEGFA-VEGFR2 signaling; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"9"	"0"	"360.5"	"308.1"	"452.5"	"282.7"	"378.5"	"333.3"	"559.9"	"574.5"	"430.9"	"635.0"	"785.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92614"	"Unconventional myosin-XVIIIa OS=Homo sapiens OX=9606 GN=MYO18A PE=1 SV=3"	"4"	"5"	"10"	"5"	"2054"	"233.0"	"6.30"	"2294.87"	"16.39"	"5"	"5"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00063, Pf01576, Pf17820"	"399687"	"ENSG00000196535"	"MYO18A"	"hsa:399687; Q5H9U3; Q5QD01; Q5W9F9; Q5W9G1; Q8IXP8; Q92614"	""	"Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease; Signaling by FLT3 fusion proteins"	"3"	"0"	"65.3"	"50.9"	"65.2"	"68.3"	"68.0"	"67.4"	"142.3"	"151.1"	"107.5"	"176.4"	"221.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09234"	"U1 small nuclear ribonucleoprotein C OS=Homo sapiens OX=9606 GN=SNRPC PE=1 SV=1"	"13"	"2"	"9"	"2"	"159"	"17.4"	"9.67"	"1646.84"	"16.37"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf06220"	"6631"	"ENSG00000124562"	"SNRPC"	"hsa:6631; P09234; Q5TAL3"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"667.5"	"374.5"	"824.3"	"396.9"	"553.8"	"508.1"	"1077.8"	"936.8"	"573.6"	"1120.7"	"2116.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P81605"	"Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2"	"35"	"7"	"12"	"7"	"110"	"11.3"	"6.54"	"2471.19"	"16.37"	"6"	"5"	"protein metabolism;stress response;transport;other biological processes"	"non-structural extracellular;other membranes"	"transporter activity;other molecular function"	"Pf15291"	"117159"	"ENSG00000161634"	"DCD"	"A5JHP2; A5JHP3; hsa:117159; P58461; P81605; Q53YJ2"	""	"Antimicrobial peptides"	"1"	"0"	"1132.0"	"289.9"	"697.9"	"397.9"	"564.5"	"715.8"	"1258.3"	"9619.6"	"1059.3"	"1090.2"	"1355.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07195"	"L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2"	"19"	"6"	"11"	"6"	"334"	"36.6"	"6.05"	"2138.26"	"16.32"	"6"	"5"	"other metabolic processes"	"other membranes;cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00056, Pf02866"	"3945"	"ENSG00000111716"	"LDHB"	"hsa:3945; P07195"	"Clear cell renal cell carcinoma pathways; CCL18 signaling pathway; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"Pyruvate metabolism"	"5"	"0"	"764.5"	"490.3"	"813.9"	"403.9"	"642.2"	"592.1"	"782.7"	"572.7"	"468.9"	"983.2"	"1392.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55735"	"Protein SEC13 homolog OS=Homo sapiens OX=9606 GN=SEC13 PE=1 SV=3"	"12"	"3"	"9"	"3"	"322"	"35.5"	"5.48"	"1457.76"	"16.31"	"3"	"3"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00400"	"6396"	"ENSG00000157020"	"SEC13"	"A8MV37; B4DXJ1; hsa:6396; P55735; Q5BJF0; Q9BRM6; Q9BUG7"	"Sterol regulatory element-binding proteins (SREBP) signaling"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; SUMOylation of DNA damage response and repair proteins; Vpr-mediated nuclear import of PICs; SARS-CoV-2 activates/modulates innate and adaptive immune responses; MHC class II antigen presentation; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; RHO GTPases Activate Formins; snRNP Assembly; Regulation of HSF1-mediated heat shock response; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; SUMOylation of chromatin organization proteins; HCMV Late Events; HCMV Early Events; EML4 and NUDC in mitotic spindle formation; Amino acids regulate mTORC1; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; COPII-mediated vesicle transport; Postmitotic nuclear pore complex (NPC) reformation"	"40"	"0"	"265.8"	"186.6"	"305.3"	"347.1"	"355.2"	"304.6"	"478.1"	"414.4"	"276.4"	"523.9"	"775.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13162"	"Peroxiredoxin-4 OS=Homo sapiens OX=9606 GN=PRDX4 PE=1 SV=1"	"11"	"4"	"11"	"1"	"271"	"30.5"	"6.29"	"1554.56"	"16.28"	"3"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00578, Pf10417"	"10549"	"ENSG00000123131"	"PRDX4"	"hsa:10549; Q13162; Q6FHT3"	"Selenium micronutrient network"	"Neutrophil degranulation"	"2"	"0"	"18.7"	"17.1"	"17.2"	"18.1"	"24.3"	"18.9"	"33.5"	"34.6"	"20.3"	"36.8"	"41.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63167"	"Dynein light chain 1, cytoplasmic OS=Homo sapiens OX=9606 GN=DYNLL1 PE=1 SV=1"	"45"	"3"	"6"	"2"	"89"	"10.4"	"7.40"	"517.07"	"16.27"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01221"	"8655"	"ENSG00000088986"	"DYNLL1"	"hsa:8655; P63167; Q15701"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; Genes related to primary cilium development (based on CRISPR); 3q29 copy number variation syndrome"	"Neutrophil degranulation; HCMV Early Events; MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Separation of Sister Chromatids; Intraflagellar transport; Resolution of Sister Chromatid Cohesion; Recruitment of NuMA to mitotic centrosomes; RHO GTPases Activate Formins; Aggrephagy; EML4 and NUDC in mitotic spindle formation; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Macroautophagy; Activation of BIM and translocation to mitochondria"	"27"	"0"	"867.9"	"376.6"	"612.2"	"512.2"	"625.1"	"624.3"	"886.9"	"889.4"	"618.4"	"797.3"	"1067.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13428"	"Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3"	"4"	"6"	"11"	"6"	"1488"	"152.0"	"9.04"	"1668.92"	"16.24"	"5"	"6"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf03546"	"6949"	"ENSG00000070814"	"TCOF1"	"A0JLU0; B4E111; hsa:6949; Q13428; Q6SC72; Q7Z5W9; Q96A52; Q99408; Q99860"	""	""	"0"	"0"	"383.1"	"214.4"	"292.8"	"335.5"	"331.9"	"432.9"	"1219.6"	"915.4"	"640.9"	"827.6"	"1077.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92747"	"Actin-related protein 2/3 complex subunit 1A OS=Homo sapiens OX=9606 GN=ARPC1A PE=2 SV=2"	"16"	"4"	"7"	"3"	"370"	"41.5"	"8.18"	"1211.50"	"16.24"	"3"	"4"	"cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf00400"	"10552"	"ENSG00000241685"	"ARPC1A"	"A4D276; B4DLQ7; D6W5S1; hsa:10552; Q7Z5U8; Q86WU5; Q8IXQ0; Q92747"	"Pathogenic Escherichia coli infection"	"Clathrin-mediated endocytosis; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; EPHB-mediated forward signaling"	"6"	"1"	"109.0"	"81.4"	"122.2"	"113.2"	"111.5"	"130.3"	"292.3"	"390.7"	"375.4"	"796.6"	"1920.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKF6"	"Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1"	"10"	"6"	"12"	"6"	"684"	"77.4"	"5.60"	"1870.70"	"16.20"	"6"	"6"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00753, Pf07521, Pf10996, Pf11718"	"51692"	"ENSG00000119203"	"CPSF3"	"hsa:51692; O14769; Q53RS2; Q96F36; Q9UKF6"	"mRNA processing"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; Transport of Mature mRNA Derived from an Intronless Transcript"	"6"	"0"	"542.6"	"319.4"	"476.9"	"497.6"	"468.1"	"547.5"	"881.5"	"857.3"	"538.5"	"865.7"	"1144.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49959"	"Double-strand break repair protein MRE11 OS=Homo sapiens OX=9606 GN=MRE11 PE=1 SV=3"	"10"	"6"	"11"	"6"	"708"	"80.5"	"5.90"	"2328.47"	"16.20"	"6"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00149, Pf04152"	"4361"	"ENSG00000020922"	"MRE11"	"B3KTC7; hsa:4361; O43475; P49959"	"miRNA regulation of DNA damage response; Homologous recombination; DDX1 as a regulatory component of the Drosha microprocessor; ATM signaling in development and disease ; Breast cancer pathway; Joubert syndrome; DNA repair pathways, full network; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; Neurogenesis regulation in the olfactory epithelium; DNA damage response"	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; Meiotic recombination; DNA Damage/Telomere Stress Induced Senescence; Nonhomologous End-Joining (NHEJ); Resolution of D-loop Structures through Holliday Junction Intermediates; Regulation of TP53 Activity through Phosphorylation; Presynaptic phase of homologous DNA pairing and strand exchange; Cytosolic sensors of pathogen-associated DNA ; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; HDR through MMEJ (alt-NHEJ); Sensing of DNA Double Strand Breaks; IRF3-mediated induction of type I IFN"	"32"	"0"	"321.1"	"181.2"	"276.8"	"294.5"	"300.3"	"337.8"	"673.9"	"640.6"	"428.9"	"682.0"	"976.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62487"	"DNA-directed RNA polymerase II subunit RPB7 OS=Homo sapiens OX=9606 GN=POLR2G PE=1 SV=1"	"33"	"4"	"7"	"4"	"172"	"19.3"	"5.54"	"707.20"	"16.15"	"2"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00575, Pf03876"	"5436"	"ENSG00000168002"	"POLR2G"	"B2R5C0; hsa:5436; P52433; P62487; Q2M1Z4"	"Pyrimidine metabolism; Eukaryotic transcription initiation"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"43"	"0"	"153.5"	"99.0"	"165.1"	"110.3"	"149.4"	"125.6"	"216.3"	"208.5"	"176.2"	"250.2"	"308.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86U42"	"Polyadenylate-binding protein 2 OS=Homo sapiens OX=9606 GN=PABPN1 PE=1 SV=3"	"22"	"7"	"11"	"7"	"306"	"32.7"	"5.06"	"2057.27"	"16.15"	"6"	"5"	"RNA metabolism OR transcription;other metabolic processes;transport;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"8106"	"ENSG00000100836"	"PABPN1"	"D3DS49; hsa:8106; O43484; Q86U42"	"mRNA processing"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; Inhibition of Host mRNA Processing and RNA Silencing"	"6"	"0"	"1015.5"	"578.3"	"812.2"	"893.0"	"811.5"	"1028.0"	"1229.5"	"956.7"	"652.3"	"1379.1"	"2045.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14974"	"Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2"	"6"	"5"	"10"	"5"	"876"	"97.1"	"4.78"	"1813.05"	"16.14"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;signal transduction;other biological processes"	"non-structural extracellular;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf03810"	"3837"	"ENSG00000108424"	"KPNB1"	"B7ZAV6; D3DTT3; hsa:3837; Q14637; Q14974; Q53XN2; Q96J27"	"Sterol regulatory element-binding proteins (SREBP) signaling; 22q11.2 copy number variation syndrome"	"Neutrophil degranulation; Assembly of the ORC complex at the origin of replication; ISG15 antiviral mechanism; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Nuclear import of Rev protein; Apoptosis induced DNA fragmentation; Interferon alpha/beta signaling; Regulation of cholesterol biosynthesis by SREBP (SREBF); SARS-CoV-1 activates/modulates innate immune responses; Initiation of Nuclear Envelope (NE) Reformation; Postmitotic nuclear pore complex (NPC) reformation; Inhibition of nitric oxide production"	"15"	"0"	"676.2"	"430.4"	"525.2"	"437.6"	"542.3"	"579.0"	"876.5"	"752.9"	"574.0"	"944.2"	"1176.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09497"	"Clathrin light chain B OS=Homo sapiens OX=9606 GN=CLTB PE=1 SV=1"	"24"	"6"	"11"	"6"	"229"	"25.2"	"4.64"	"1927.26"	"16.09"	"6"	"5"	"transport"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf01086"	"1212"	"ENSG00000175416"	"CLTB"	"hsa:1212; P09497; Q53Y37; Q6FHW1"	"Ebola virus infection in host; Fragile X syndrome; 5q35 copy number variation"	"Lysosome Vesicle Biogenesis; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; Formation of annular gap junctions"	"11"	"0"	"561.5"	"360.5"	"491.7"	"513.1"	"518.7"	"581.2"	"855.9"	"759.5"	"574.9"	"882.7"	"1190.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23193"	"Transcription elongation factor A protein 1 OS=Homo sapiens OX=9606 GN=TCEA1 PE=1 SV=2"	"20"	"6"	"11"	"6"	"301"	"33.9"	"8.38"	"1942.41"	"15.99"	"6"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01096, Pf07500, Pf08711"	"6917"	"ENSG00000187735"	"TCEA1"	"A6NF25; A8K339; hsa:6917; P23193; Q15563; Q6FG87"	""	"Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	"15"	"0"	"279.9"	"166.1"	"260.6"	"343.5"	"308.9"	"362.2"	"919.7"	"849.3"	"637.1"	"1074.6"	"1775.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25788"	"Proteasome subunit alpha type-3 OS=Homo sapiens OX=9606 GN=PSMA3 PE=1 SV=2"	"15"	"4"	"9"	"4"	"255"	"28.4"	"5.33"	"1650.36"	"15.90"	"3"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00227, Pf10584"	"5684"	"ENSG00000100567"	"PSMA3"	"B2RCK6; hsa:5684; P25788; Q86U83; Q8N1D8; Q9BS70"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Cross-presentation of soluble exogenous antigens (endosomes); Regulation of ornithine decarboxylase (ODC); Somitogenesis"	"62"	"0"	"459.8"	"276.7"	"458.3"	"423.0"	"459.3"	"444.1"	"1031.7"	"919.5"	"725.4"	"1106.9"	"1541.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62993"	"Growth factor receptor-bound protein 2 OS=Homo sapiens OX=9606 GN=GRB2 PE=1 SV=1"	"23"	"5"	"10"	"5"	"217"	"25.2"	"6.32"	"1601.13"	"15.85"	"5"	"5"	"cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00017, Pf00018"	"2885"	"ENSG00000177885"	"GRB2"	"hsa:2885; P29354; P62993; Q14450; Q63057; Q63059"	"IL-5 signaling pathway; Integrin-mediated cell adhesion; Leptin signaling pathway; Prolactin signaling pathway; IL-9 signaling pathway; Pilocytic astrocytoma; Glioblastoma signaling pathways; Androgen receptor network in prostate cancer; B cell receptor signaling pathway; TNF-alpha signaling pathway; Interleukin-11 signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Alpha 6 beta 4 signaling pathway; IL-3 signaling pathway; Kit receptor signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; RAC1/PAK1/p38/MMP2 pathway; IL6 signaling pathway; Hepatitis C and hepatocellular carcinoma; BDNF-TrkB signaling; Physico-chemical features and toxicity-associated pathways; MAPK signaling pathway; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Embryonic stem cell pluripotency pathways; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; IL-4 signaling pathway; p38 MAPK signaling pathway; Endometrial cancer; PI3K-Akt signaling pathway; MAPK cascade; Ras signaling; Epithelial to mesenchymal transition in colorectal cancer; Breast cancer pathway; Thermogenesis; EGF/EGFR signaling pathway; Envelope proteins and their potential roles in EDMD physiopathology; Fragile X syndrome; Gastrin signaling pathway; Hepatitis B infection; Melanoma; Thyroid hormones production and peripheral downstream signaling effects; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; IL-2 signaling pathway; 7q11.23 copy number variation syndrome; 16p11.2 distal deletion syndrome; Modulators of TCR signaling and T cell activation; Kallmann syndrome; Pleural mesothelioma; Congenital generalized lipodystrophy; GDNF signaling; 2q13 copy number variation syndrome; A network map of Macrophage-stimulating protein (MSP) signaling; 4p16.3 copy number variation; 5q35 copy number variation; EPO receptor signaling; ErbB signaling pathway; T-cell receptor signaling pathway; DNA damage response (only ATM dependent)"	"Signaling by ALK fusions and activated point mutants; Signaling by CSF3 (G-CSF); STAT5 activation downstream of FLT3 ITD mutants; Interleukin-15 signaling"	"68"	"0"	"942.8"	"598.3"	"890.0"	"788.3"	"802.1"	"943.7"	"1244.2"	"1225.0"	"994.6"	"1606.4"	"2557.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UII2"	"ATPase inhibitor, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5IF1 PE=1 SV=1"	"25"	"5"	"12"	"5"	"106"	"12.2"	"9.35"	"1898.84"	"15.77"	"5"	"5"	"cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"mitochondrion;other cell component"	"enzyme regulator activity;other molecular function"	"Pf04568"	"93974"	"ENSG00000130770; ENSG00000285390"	"ATP5IF1"	"hsa:93974; Q5JXL8; Q6IAQ7; Q9BSL9; Q9UII2"	"Electron transport chain: OXPHOS system in mitochondria"	""	"1"	"0"	"1238.6"	"642.0"	"879.2"	"1063.8"	"989.7"	"1126.8"	"4581.9"	"4345.4"	"3156.6"	"4179.8"	"5526.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19784"	"Casein kinase II subunit alpha' OS=Homo sapiens OX=9606 GN=CSNK2A2 PE=1 SV=1"	"18"	"5"	"9"	"4"	"350"	"41.2"	"8.56"	"1441.53"	"15.75"	"4"	"5"	"cell-cell signaling;cell cycle OR cell proliferation;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1459"	"ENSG00000070770"	"CSNK2A2"	"hsa:1459; P19784"	"Alzheimer's disease and miRNA effects; Allograft rejection; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Measles virus infection; Pleural mesothelioma; Alzheimer's disease"	"Regulation of TP53 Activity through Phosphorylation; Regulation of PTEN stability and activity; KEAP1-NFE2L2 pathway; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; WNT mediated activation of DVL; Signal transduction by L1; Receptor Mediated Mitophagy; Condensation of Prometaphase Chromosomes; Synthesis of PC"	"19"	"0"	"136.2"	"95.0"	"126.3"	"115.2"	"124.3"	"133.6"	"682.2"	"673.5"	"560.9"	"842.0"	"967.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92900"	"Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2"	"6"	"5"	"9"	"5"	"1129"	"124.3"	"6.61"	"1464.46"	"15.67"	"4"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09416, Pf13086, Pf13087, Pf18141"	"5976"	"ENSG00000005007"	"UPF1"	"hsa:5976; O00239; O43343; Q86Z25; Q92842; Q92900"	"Pathophysiological roles of DUX4 in FSHD1"	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"3"	"0"	"180.7"	"123.5"	"168.6"	"188.8"	"177.1"	"219.2"	"470.0"	"456.4"	"363.2"	"520.4"	"640.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P45973"	"Chromobox protein homolog 5 OS=Homo sapiens OX=9606 GN=CBX5 PE=1 SV=1"	"27"	"4"	"10"	"3"	"191"	"22.2"	"5.86"	"2424.47"	"15.63"	"4"	"4"	"cell organization and biogenesis;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00385, Pf01393"	"23468"	"ENSG00000094916"	"CBX5"	"B2R8T9; hsa:23468; P45973"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; 22q11.2 copy number variation syndrome"	"Factors involved in megakaryocyte development and platelet production; SUMOylation of chromatin organization proteins; Transcriptional Regulation by E2F6"	"5"	"0"	"149.0"	"91.4"	"139.5"	"163.6"	"130.4"	"161.2"	"442.6"	"348.1"	"198.4"	"286.8"	"328.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EE3"	"Nucleoporin SEH1 OS=Homo sapiens OX=9606 GN=SEH1L PE=1 SV=3"	"11"	"2"	"5"	"2"	"360"	"39.6"	"8.09"	"959.18"	"15.60"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;other biological processes"	"other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00400"	"81929"	"ENSG00000085415"	"SEH1L"	"A8K5B1; hsa:81929; Q8NFU6; Q96EE3; Q96MH3; Q9C069"	""	"Amino acids regulate mTORC1"	"1"	"0"	"35.7"	"21.8"	"32.6"	"39.5"	"36.1"	"35.8"	"61.6"	"73.9"	"68.8"	"89.5"	"115.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46779"	"60S ribosomal protein L28 OS=Homo sapiens OX=9606 GN=RPL28 PE=1 SV=3"	"24"	"4"	"11"	"4"	"137"	"15.7"	"12.02"	"1770.35"	"15.59"	"3"	"4"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01778"	"6158"	"ENSG00000108107"	"RPL28"	"B2R4A6; B4DEP9; C9JB50; E9PB24; G5E9L2; hsa:6158; P46779; Q6IAY0; Q96FX1; Q9BWQ0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"917.6"	"567.7"	"832.3"	"590.9"	"734.1"	"753.0"	"2166.5"	"1876.0"	"1274.0"	"2183.1"	"3199.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96FN4"	"Copine-2 OS=Homo sapiens OX=9606 GN=CPNE2 PE=1 SV=3"	"9"	"4"	"9"	"3"	"548"	"61.2"	"6.07"	"1868.63"	"15.57"	"4"	"3"	"other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00168, Pf07002"	"221184"	"ENSG00000140848"	"CPNE2"	"hsa:221184; Q68D19; Q719H8; Q86XP9; Q96FN4"	""	""	"0"	"0"	"95.7"	"74.7"	"87.6"	"79.8"	"90.8"	"94.9"	"145.2"	"150.0"	"118.8"	"178.9"	"259.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30405"	"Peptidyl-prolyl cis-trans isomerase F, mitochondrial OS=Homo sapiens OX=9606 GN=PPIF PE=1 SV=1"	"25"	"7"	"13"	"5"	"207"	"22.0"	"9.38"	"2118.11"	"15.43"	"6"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf00160"	"10105"	"ENSG00000108179"	"PPIF"	"hsa:10105; P30405; Q2YDB7; Q5W131"	"Alzheimer's disease and miRNA effects; Alzheimer's disease"	""	"2"	"1"	"1001.6"	"512.5"	"818.6"	"689.0"	"732.4"	"800.5"	"1188.7"	"1159.5"	"831.7"	"1383.0"	"3131.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11586"	"C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=3"	"8"	"6"	"11"	"6"	"935"	"101.5"	"7.30"	"1899.08"	"15.42"	"6"	"5"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"226.4"	"150.6"	"184.3"	"155.0"	"208.2"	"206.3"	"449.2"	"448.4"	"336.7"	"508.4"	"644.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BZZ5"	"Apoptosis inhibitor 5 OS=Homo sapiens OX=9606 GN=API5 PE=1 SV=3"	"15"	"5"	"8"	"5"	"524"	"59.0"	"7.34"	"1245.20"	"15.41"	"4"	"4"	"other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf05918"	"8539"	"ENSG00000166181"	"API5"	"B4DGR0; B4DRJ2; B4E283; D3DR21; G3V1C3; hsa:8539; O15441; Q9BZZ5; Q9Y4J7"	""	""	"0"	"0"	"56.9"	"36.1"	"50.6"	"37.4"	"67.1"	"72.4"	"203.8"	"166.6"	"126.5"	"216.4"	"270.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60228"	"Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1"	"16"	"6"	"10"	"6"	"445"	"52.2"	"6.04"	"1644.69"	"15.39"	"5"	"5"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01399, Pf09440"	"3646"	"ENSG00000104408"	"EIF3E"	"hsa:3646; O43902; P60228; Q64058; Q64059; Q64252; Q6FG33; Q8WVK4"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition"	"8"	"0"	"460.4"	"299.9"	"441.4"	"345.5"	"448.4"	"453.5"	"884.2"	"818.7"	"617.3"	"842.3"	"1165.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62899"	"60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1"	"30"	"4"	"9"	"4"	"125"	"14.5"	"10.54"	"1222.66"	"15.38"	"3"	"4"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01198"	"6160"	"ENSG00000071082"	"RPL31"	"B7Z4K2; D3DVJ4; hsa:6160; P12947; P62899; Q53SQ5; Q6IRZ0; Q6LBJ6"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"459.3"	"325.2"	"423.0"	"345.9"	"481.3"	"812.2"	"1341.2"	"1181.4"	"829.7"	"1332.2"	"1631.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6NZY4"	"Zinc finger CCHC domain-containing protein 8 OS=Homo sapiens OX=9606 GN=ZCCHC8 PE=1 SV=2"	"6"	"3"	"7"	"3"	"707"	"78.5"	"4.87"	"1597.18"	"15.38"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00098, Pf04046"	"55596"	"ENSG00000033030"	"ZCCHC8"	"hsa:55596; Q6NZY4; Q7L2P6; Q8N2K5; Q96SK7; Q9NSS2; Q9NSS3"	""	""	"0"	"0"	"123.5"	"74.4"	"108.0"	"111.2"	"116.7"	"137.4"	"223.3"	"204.4"	"147.8"	"251.9"	"338.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WVV9"	"Heterogeneous nuclear ribonucleoprotein L-like OS=Homo sapiens OX=9606 GN=HNRNPLL PE=1 SV=1"	"9"	"4"	"10"	"3"	"542"	"60.0"	"7.72"	"1595.49"	"15.38"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf11835, Pf13893"	"92906"	"ENSG00000143889"	"HNRNPLL"	"hsa:92906; Q53T80; Q5JB51; Q5JB52; Q659B9; Q8IVH5; Q8IVH6; Q8WVV9; Q96HR5"	""	""	"0"	"0"	"44.8"	"26.7"	"54.1"	"53.9"	"59.2"	"53.7"	"138.5"	"127.7"	"67.8"	"69.5"	"68.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKE5"	"TRAF2 and NCK-interacting protein kinase OS=Homo sapiens OX=9606 GN=TNIK PE=1 SV=1"	"3"	"4"	"10"	"1"	"1360"	"154.8"	"7.17"	"1071.90"	"15.35"	"2"	"4"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00780"	"23043"	"ENSG00000154310"	"TNIK"	"A7E2A3; A8K4U1; D3DNQ6; hsa:23043; O60298; Q8WUY7; Q9UKD8; Q9UKD9; Q9UKE0; Q9UKE1; Q9UKE2; Q9UKE3; Q9UKE4; Q9UKE5"	"Hippo-YAP signaling; Pleural mesothelioma"	"Oxidative Stress Induced Senescence"	"3"	"0"	"89.8"	"46.7"	"72.7"	"69.7"	"82.3"	"86.3"	"168.2"	"258.3"	"212.6"	"250.1"	"347.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48739"	"Phosphatidylinositol transfer protein beta isoform OS=Homo sapiens OX=9606 GN=PITPNB PE=1 SV=2"	"22"	"7"	"10"	"7"	"271"	"31.5"	"6.87"	"1700.44"	"15.32"	"6"	"3"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;ER/Golgi;other cell component"	"transporter activity;other molecular function"	"Pf02121"	"23760"	"ENSG00000180957"	"PITPNB"	"B3KYB8; B7Z7Q0; hsa:23760; P48739; Q8N5W1"	""	"PI and PC transport between ER and Golgi membranes"	"1"	"0"	"868.8"	"381.3"	"487.6"	"717.1"	"505.0"	"755.0"	"1032.5"	"893.4"	"738.5"	"1187.1"	"1652.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96A72"	"Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1"	"41"	"5"	"9"	"5"	"148"	"17.3"	"6.39"	"1614.90"	"15.19"	"4"	"5"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf02792"	"55110"	"ENSG00000111196"	"MAGOHB"	"hsa:55110; Q96A72"	""	"Regulation of expression of SLITs and ROBOs; mRNA Splicing - Major Pathway; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	"6"	"0"	"249.2"	"194.4"	"230.4"	"186.3"	"268.0"	"248.1"	"421.1"	"356.4"	"292.7"	"725.4"	"845.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IXB1"	"DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2"	"5"	"4"	"10"	"4"	"793"	"91.0"	"7.18"	"1975.56"	"15.19"	"4"	"4"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"ER/Golgi"	"other molecular function"	"Pf00085, Pf00226"	"54431"	"ENSG00000077232"	"DNAJC10"	"hsa:54431; Q17RJ6; Q3B7W8; Q4ZG06; Q53QT7; Q6UWZ6; Q86T61; Q8IXB1; Q8NC82; Q8TD87; Q96K38; Q96K44; Q96K54; Q9NSY6"	""	""	"0"	"0"	"198.8"	"132.7"	"199.0"	"215.3"	"212.7"	"242.9"	"712.1"	"726.4"	"597.0"	"793.7"	"1091.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50914"	"60S ribosomal protein L14 OS=Homo sapiens OX=9606 GN=RPL14 PE=1 SV=4"	"31"	"8"	"11"	"8"	"215"	"23.4"	"10.93"	"1607.59"	"15.18"	"5"	"6"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01929"	"9045"	"ENSG00000188846"	"RPL14"	"hsa:9045; P50914; Q45RF0; Q53G20; Q8TBD5; Q8WUT0; Q92579; Q96GR0; Q9BSB8; Q9BW65; Q9BYF6"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"941.4"	"635.4"	"835.6"	"709.8"	"843.7"	"888.3"	"3235.3"	"2915.6"	"1951.4"	"2996.3"	"3486.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12996"	"Cleavage stimulation factor subunit 3 OS=Homo sapiens OX=9606 GN=CSTF3 PE=1 SV=1"	"10"	"6"	"12"	"6"	"717"	"82.9"	"8.12"	"2479.11"	"15.18"	"6"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf05843"	"1479"	"ENSG00000176102"	"CSTF3"	"A8K471; D3DR04; E9PB40; hsa:1479; Q12996; Q32P22; Q96FQ8; Q96QD6; Q96QK4"	"mRNA processing"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"5"	"0"	"144.0"	"83.3"	"144.9"	"132.5"	"151.1"	"172.2"	"431.3"	"386.7"	"276.9"	"472.9"	"737.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P24752"	"Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1"	"10"	"4"	"10"	"4"	"427"	"45.2"	"8.85"	"1749.73"	"15.15"	"4"	"4"	"other metabolic processes;stress response;developmental processes;other biological processes"	"mitochondrion;ER/Golgi"	"other molecular function"	"Pf00108, Pf02803"	"38"	"ENSG00000075239"	"ACAT1"	"B2R6H1; G3XAB4; hsa:38; P24752; Q96FG8"	"Fatty acid beta-oxidation; Tryptophan metabolism; SARS-CoV-2 and COVID-19 pathway"	"Branched-chain amino acid catabolism; Utilization of Ketone Bodies; Synthesis of Ketone Bodies"	"6"	"0"	"374.4"	"222.8"	"328.0"	"323.2"	"347.6"	"406.6"	"651.0"	"603.4"	"491.6"	"850.9"	"1425.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00425"	"Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2"	"7"	"3"	"8"	"2"	"579"	"63.7"	"8.87"	"1436.05"	"15.11"	"3"	"3"	"protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf00076"	"10643"	"ENSG00000136231"	"IGF2BP3"	"A0A4Z5; hsa:10643; O00425; Q63HM0; Q6MZZ2; Q86VB1"	""	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"	"1"	"0"	"60.5"	"40.7"	"59.0"	"62.8"	"70.4"	"74.1"	"106.4"	"85.7"	"59.7"	"117.9"	"148.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKK9"	"ADP-sugar pyrophosphatase OS=Homo sapiens OX=9606 GN=NUDT5 PE=1 SV=1"	"24"	"6"	"12"	"6"	"219"	"24.3"	"4.94"	"2503.57"	"15.07"	"6"	"5"	"cell organization and biogenesis;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00293"	"11164"	"ENSG00000165609"	"NUDT5"	"A8K516; hsa:11164; Q6IAG0; Q9UH49; Q9UKK9"	""	"Phosphate bond hydrolysis by NUDT proteins"	"1"	"0"	"665.8"	"416.8"	"612.3"	"521.0"	"595.0"	"524.9"	"732.6"	"654.8"	"443.6"	"797.3"	"1209.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P43490"	"Nicotinamide phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=NAMPT PE=1 SV=1"	"10"	"4"	"8"	"4"	"491"	"55.5"	"7.15"	"972.13"	"15.04"	"2"	"4"	"cell-cell signaling;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf04095, Pf18127"	"10135"	"ENSG00000105835"	"NAMPT"	"A4D0Q9; A4D0R0; hsa:10135; P43490; Q3KQV0; Q8WW95"	"Adipogenesis; NAD metabolism, sirtuins and aging; NAD+ metabolism; NAD+ biosynthetic pathways; Caloric restriction and aging; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence"	"NPAS4 regulates expression of target genes; BMAL1:CLOCK,NPAS2 activates circadian gene expression; Nicotinamide salvaging"	"9"	"0"	"363.7"	"157.5"	"223.4"	"376.0"	"319.0"	"387.2"	"529.5"	"544.3"	"400.8"	"640.3"	"847.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96BP3"	"Peptidylprolyl isomerase domain and WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=PPWD1 PE=1 SV=1"	"9"	"6"	"10"	"6"	"646"	"73.5"	"7.15"	"1297.82"	"14.96"	"4"	"6"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00160, Pf00400"	"23398"	"ENSG00000113593"	"PPWD1"	"B4DWR9; hsa:23398; Q15002; Q7KZ89; Q96BP3"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"258.9"	"197.3"	"252.3"	"207.5"	"221.0"	"252.0"	"532.0"	"516.2"	"413.5"	"644.6"	"907.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82650"	"28S ribosomal protein S22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS22 PE=1 SV=1"	"12"	"4"	"10"	"4"	"360"	"41.3"	"7.90"	"1605.22"	"14.94"	"4"	"4"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf10245"	"56945"	"ENSG00000175110"	"MRPS22"	"hsa:56945; P82650; Q9H3I1"	"Primary ovarian insufficiency"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"4"	"0"	"210.1"	"144.9"	"167.3"	"163.6"	"153.4"	"201.5"	"300.1"	"277.0"	"219.6"	"326.4"	"404.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BWS9"	"Chitinase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHID1 PE=1 SV=1"	"12"	"5"	"10"	"5"	"393"	"44.9"	"8.63"	"1756.40"	"14.91"	"5"	"5"	"other metabolic processes;stress response;other biological processes"	"non-structural extracellular;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00704"	"66005"	"ENSG00000177830"	"CHID1"	"B3KWB0; hsa:66005; Q8NBM9; Q96CZ3; Q96S93; Q96SK0; Q9BWS9; Q9BY52"	""	"Platelet degranulation"	"1"	"0"	"122.3"	"70.5"	"126.6"	"111.1"	"168.9"	"155.9"	"1675.2"	"1617.9"	"1300.4"	"2448.9"	"4541.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P10515"	"Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3"	"7"	"4"	"9"	"4"	"647"	"69.0"	"7.84"	"1394.07"	"14.89"	"3"	"4"	"other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf00198, Pf00364, Pf02817"	"1737"	"ENSG00000150768"	"DLAT"	"hsa:1737; P10515; Q16783; Q53EP3"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Neuroinflammation and glutamatergic signaling; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"Glyoxylate metabolism and glycine degradation; Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid"	"8"	"0"	"357.3"	"245.6"	"366.4"	"283.2"	"339.7"	"350.6"	"226.6"	"244.8"	"164.2"	"296.7"	"477.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49750"	"YLP motif-containing protein 1 OS=Homo sapiens OX=9606 GN=YLPM1 PE=1 SV=4"	"3"	"5"	"9"	"5"	"2146"	"241.5"	"6.55"	"1225.43"	"14.83"	"4"	"5"	"other biological processes"	"cytosol;nucleus"	""	"Pf13671"	"56252"	"ENSG00000119596"	"YLPM1"	"hsa:56252; P49750; P49752; Q96I64; Q9P1V7"	""	""	"0"	"0"	"228.5"	"129.1"	"209.2"	"208.2"	"247.6"	"236.8"	"634.5"	"613.8"	"431.6"	"656.8"	"822.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P41252"	"Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2"	"5"	"5"	"10"	"5"	"1262"	"144.4"	"6.15"	"1666.84"	"14.78"	"5"	"5"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00133, Pf08264, Pf19302"	"3376"	"ENSG00000196305"	"IARS1"	"A8KAE9; hsa:3376; P41252; Q5TCD0; Q7Z3T4; Q9H588"	"Amino acid metabolism"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"3"	"0"	"207.7"	"148.3"	"185.4"	"193.3"	"187.3"	"209.7"	"344.5"	"306.9"	"229.3"	"378.7"	"503.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25787"	"Proteasome subunit alpha type-2 OS=Homo sapiens OX=9606 GN=PSMA2 PE=1 SV=2"	"14"	"3"	"9"	"3"	"234"	"25.9"	"7.43"	"1741.01"	"14.77"	"3"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf00227, Pf10584"	"5683"	"ENSG00000106588"	"PSMA2"	"hsa:5683; P25787; Q6ICS6; Q9BU45"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"ER-Phagosome pathway; Neutrophil degranulation; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"63"	"0"	"316.0"	"176.7"	"294.3"	"245.4"	"307.2"	"273.8"	"696.4"	"634.8"	"515.8"	"792.0"	"1043.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P98179"	"RNA-binding protein 3 OS=Homo sapiens OX=9606 GN=RBM3 PE=1 SV=1"	"24"	"3"	"9"	"3"	"157"	"17.2"	"8.91"	"1571.15"	"14.77"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"translation activity"	"Pf00076"	"5935"	"ENSG00000102317"	"RBM3"	"hsa:5935; P98179"	""	""	"0"	"0"	"529.5"	"553.7"	"512.5"	"481.9"	"488.8"	"644.1"	"1328.1"	"1410.4"	"1308.4"	"1461.3"	"1365.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99873"	"Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3"	"8"	"3"	"10"	"3"	"371"	"42.4"	"5.35"	"1769.36"	"14.76"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13649"	"3276"	"ENSG00000126457"	"PRMT1"	"A0A087X1W2; B4E3C3; G5E9B6; H7C2I1; hsa:3276; Q15529; Q2VP93; Q6LEU5; Q8WUW5; Q99872; Q99873; Q99874; Q9NZ04; Q9NZ05; Q9NZ06"	"Energy metabolism; mRNA processing; Nitric oxide metabolism in cystic fibrosis; 16p11.2 distal deletion syndrome; Interferon type I signaling pathways"	"Estrogen-dependent gene expression; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Extra-nuclear estrogen signaling; RMTs methylate histone arginines; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Maturation of nucleoprotein"	"11"	"0"	"302.2"	"200.2"	"320.8"	"175.3"	"264.2"	"278.4"	"411.4"	"393.8"	"318.9"	"478.3"	"671.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15691"	"Microtubule-associated protein RP/EB family member 1 OS=Homo sapiens OX=9606 GN=MAPRE1 PE=1 SV=3"	"21"	"5"	"8"	"5"	"268"	"30.0"	"5.14"	"920.30"	"14.69"	"3"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf03271"	"22919"	"ENSG00000101367"	"MAPRE1"	"B2R6I7; E1P5M8; hsa:22919; Q15691; Q3KQS8"	"Microtubule cytoskeleton regulation"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; The role of GTSE1 in G2/M progression after G2 checkpoint; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"15"	"0"	"374.4"	"229.9"	"305.2"	"289.3"	"312.7"	"345.6"	"554.1"	"555.7"	"420.2"	"635.5"	"847.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15370"	"Elongin-B OS=Homo sapiens OX=9606 GN=ELOB PE=1 SV=1"	"42"	"5"	"9"	"5"	"118"	"13.1"	"4.88"	"1362.42"	"14.65"	"4"	"5"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00240"	"6923"	"ENSG00000103363"	"ELOB"	"B7WPD3; hsa:6923; Q15370"	"Dual hijack model of Vif in HIV infection; Type 2 papillary renal cell carcinoma; Hijack of ubiquitination by SARS-CoV-2; Modulators of TCR signaling and T cell activation"	"Inactivation of CSF3 (G-CSF) signaling; Antigen processing: Ubiquitination & Proteasome degradation; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Vif-mediated degradation of APOBEC3G; Neddylation; Regulation of expression of SLITs and ROBOs; TP53 Regulates Transcription of DNA Repair Genes; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events"	"21"	"0"	"941.6"	"471.1"	"715.6"	"767.7"	"724.8"	"728.6"	"964.0"	"925.9"	"643.9"	"1034.3"	"1639.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y606"	"tRNA pseudouridine synthase A OS=Homo sapiens OX=9606 GN=PUS1 PE=1 SV=3"	"15"	"5"	"8"	"5"	"427"	"47.4"	"8.41"	"1023.81"	"14.64"	"3"	"5"	"RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01416"	"80324"	"ENSG00000177192"	"PUS1"	"A8K877; B3KQC1; hsa:80324; Q8WYT2; Q9BU44; Q9Y606"	""	""	"0"	"0"	"63.6"	"44.3"	"64.8"	"64.7"	"65.1"	"76.8"	"130.8"	"189.1"	"129.3"	"343.8"	"589.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNX4"	"WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1"	"5"	"4"	"7"	"4"	"943"	"106.0"	"6.64"	"1012.80"	"14.64"	"3"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00400, Pf04003, Pf12894"	"10885"	"ENSG00000065183"	"WDR3"	"hsa:10885; Q9UNX4"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"74.0"	"56.1"	"77.9"	"68.3"	"93.8"	"86.9"	"217.2"	"210.9"	"201.2"	"409.0"	"585.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NVA2"	"Septin-11 OS=Homo sapiens OX=9606 GN=SEPTIN11 PE=1 SV=3"	"10"	"4"	"9"	"3"	"429"	"49.4"	"6.81"	"1355.02"	"14.61"	"4"	"4"	"cell cycle OR cell proliferation"	"cytoskeleton;other cell component"	"other molecular function"	"Pf00735"	"55752"	"ENSG00000138758"	"SEPTIN11"	"B7Z7Z6; E9KL32; hsa:55752; Q4W5G1; Q7L4N1; Q96SP1; Q9NVA2; Q9UFY9"	"22q11.2 copy number variation syndrome"	""	"1"	"1"	"99.6"	"66.8"	"102.0"	"84.9"	"107.3"	"127.3"	"429.3"	"384.5"	"295.3"	"480.7"	"846.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P84090"	"Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1"	"34"	"3"	"8"	"3"	"104"	"12.3"	"5.92"	"864.79"	"14.60"	"2"	"3"	"cell cycle OR cell proliferation;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf01133"	"2079"	"ENSG00000100632"	"ERH"	"B2R5H2; hsa:2079; P70659; P84090; Q14259"	""	""	"0"	"0"	"397.5"	"327.3"	"404.8"	"355.1"	"440.5"	"449.8"	"765.0"	"751.4"	"665.0"	"1006.2"	"1144.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15446"	"DNA-directed RNA polymerase I subunit RPA34 OS=Homo sapiens OX=9606 GN=CD3EAP PE=1 SV=1"	"9"	"3"	"6"	"3"	"510"	"55.0"	"8.51"	"1492.41"	"14.59"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;signal transduction"	"cytosol;mitochondrion;nucleus;other cell component"	""	"Pf08208"	"10849"	"ENSG00000117877"	"POLR1G"	"hsa:10849; O15446; Q32N11; Q7Z5U2; Q9UPF6"	"2q13 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"6"	"0"	"42.9"	"27.0"	"38.2"	"47.1"	"39.8"	"56.7"	"153.8"	"404.1"	"484.4"	"1023.8"	"1169.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BY77"	"Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2"	"11"	"4"	"8"	"4"	"421"	"46.1"	"9.99"	"1411.84"	"14.58"	"4"	"4"	"other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"84271"	"ENSG00000100227"	"POLDIP3"	"A8K6F8; A8K6V9; hsa:84271; Q009A7; Q5H972; Q6PGN6; Q7Z6Z0; Q9BY77; Q9NSP5; Q9NSP6"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"3"	"0"	"181.2"	"115.8"	"147.8"	"148.5"	"171.7"	"191.0"	"370.4"	"349.1"	"289.5"	"419.8"	"496.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q09161"	"Nuclear cap-binding protein subunit 1 OS=Homo sapiens OX=9606 GN=NCBP1 PE=1 SV=1"	"7"	"5"	"10"	"5"	"790"	"91.8"	"6.43"	"1703.75"	"14.51"	"5"	"5"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02854, Pf09088, Pf09090"	"4686"	"ENSG00000136937"	"NCBP1"	"B2R718; hsa:4686; Q09161; Q59G76; Q5T1V0; Q5T7X2"	"mRNA processing; 3q29 copy number variation syndrome"	"Regulation of expression of SLITs and ROBOs; mRNA Splicing - Major Pathway; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; RNA polymerase II transcribes snRNA genes; Processing of Intronless Pre-mRNAs; Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; snRNP Assembly; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Abortive elongation of HIV-1 transcript in the absence of Tat; RNA Polymerase II Pre-transcription Events; mRNA Capping; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Signaling by FGFR2 IIIa TM; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"29"	"0"	"200.9"	"119.4"	"186.2"	"152.1"	"181.4"	"187.3"	"430.0"	"400.4"	"320.4"	"553.4"	"622.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49773"	"Histidine triad nucleotide-binding protein 1 OS=Homo sapiens OX=9606 GN=HINT1 PE=1 SV=2"	"33"	"3"	"7"	"3"	"126"	"13.8"	"6.95"	"991.12"	"14.43"	"2"	"3"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf01230"	"3094"	"ENSG00000169567"	"HINT1"	"hsa:3094; P49773; Q9H5W8"	""	""	"0"	"0"	"577.4"	"454.2"	"591.9"	"449.8"	"619.5"	"503.1"	"707.1"	"649.4"	"571.8"	"748.9"	"1102.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TDN4"	"CDK5 and ABL1 enzyme substrate 1 OS=Homo sapiens OX=9606 GN=CABLES1 PE=1 SV=2"	"10"	"5"	"9"	"5"	"633"	"67.6"	"9.17"	"1571.85"	"14.37"	"4"	"5"	"cell cycle OR cell proliferation;developmental processes;other biological processes"	"cytosol;nucleus"	""	"Pf00134"	"91768"	"ENSG00000134508"	"CABLES1"	"B4DK60; hsa:91768; Q8N3Y8; Q8NA22; Q8TDN4; Q9BTG1"	""	"Factors involved in megakaryocyte development and platelet production; Cyclin E associated events during G1/S transition ; Cyclin A:Cdk2-associated events at S phase entry"	"3"	"0"	"34.4"	"17.3"	"34.4"	"34.3"	"39.7"	"41.5"	"101.2"	"165.5"	"155.6"	"242.6"	"324.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13554"	"Calcium/calmodulin-dependent protein kinase type II subunit beta OS=Homo sapiens OX=9606 GN=CAMK2B PE=1 SV=3"	"6"	"3"	"8"	"1"	"666"	"72.6"	"7.27"	"1726.78"	"14.36"	"3"	"3"	"protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00069, Pf08332"	"816"	"ENSG00000058404"	"CAMK2B"	"A4D2K0; A4D2K1; A4D2K2; A4D2K3; A4D2K4; A4D2K5; A4D2K6; hsa:816; O95437; O95438; O95599; Q13554; Q9UGH7; Q9UGH8; Q9UGH9; Q9UNX0; Q9UNX7; Q9UP00; Q9Y5N4; Q9Y6F4"	"Primary focal segmental glomerulosclerosis (FSGS); Myometrial relaxation and contraction pathways; Serotonin and anxiety; NO/cGMP/PKG mediated neuroprotection; Wnt signaling; Non-genomic actions of 1,25 dihydroxyvitamin D3; Synaptic signaling pathways associated with autism spectrum disorder; Fragile X syndrome; Disruption of postsynaptic signaling by CNV; Neuroinflammation and glutamatergic signaling; GDNF signaling; Hippocampal synaptogenesis and neurogenesis; Calcium regulation in cardiac cells; ErbB signaling pathway"	"Signaling by BRAF and RAF1 fusions; Ion transport by P-type ATPases; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; Assembly and cell surface presentation of NMDA receptors; Ion homeostasis; Interferon gamma signaling; RAF activation; Ras activation upon Ca2+ influx through NMDA receptor; Regulation of MECP2 expression and activity; Unblocking of NMDA receptors, glutamate binding and activation; Negative regulation of NMDA receptor-mediated neuronal transmission; Long-term potentiation; Trafficking of AMPA receptors; Phase 0 - rapid depolarisation; HSF1-dependent transactivation; CaMK IV-mediated phosphorylation of CREB; CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde"	"35"	"2"	"176.3"	"107.1"	"155.7"	"144.5"	"159.4"	"169.2"	"271.0"	"249.9"	"193.9"	"294.8"	"398.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q06330"	"Recombining binding protein suppressor of hairless OS=Homo sapiens OX=9606 GN=RBPJ PE=1 SV=3"	"15"	"5"	"9"	"5"	"500"	"55.6"	"7.18"	"1251.25"	"14.33"	"4"	"5"	"cell cycle OR cell proliferation;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09270, Pf09271, Pf20144"	"3516"	"ENSG00000168214"	"RBPJ"	"B4DY22; hsa:3516; Q06330; Q5XKH9; Q6P1N3"	"Neural crest differentiation; Notch signaling; Canonical and non-canonical Notch signaling; PTF1A related regulatory pathway; Epithelial to mesenchymal transition in colorectal cancer; Osteoblast differentiation and related diseases; Genetic causes of porto-sinusoidal vascular disease; Notch signaling pathway"	"Somitogenesis; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; NOTCH1 Intracellular Domain Regulates Transcription; Formation of paraxial mesoderm; Pre-NOTCH Transcription and Translation; Notch-HLH transcription pathway; NOTCH3 Intracellular Domain Regulates Transcription; Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells; NOTCH2 intracellular domain regulates transcription; NOTCH4 Intracellular Domain Regulates Transcription; RUNX3 regulates NOTCH signaling"	"20"	"0"	"117.7"	"52.7"	"123.1"	"112.3"	"176.1"	"146.1"	"383.7"	"441.5"	"432.6"	"860.6"	"1294.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60610"	"Protein diaphanous homolog 1 OS=Homo sapiens OX=9606 GN=DIAPH1 PE=1 SV=2"	"4"	"4"	"8"	"4"	"1272"	"141.3"	"5.41"	"1511.53"	"14.32"	"4"	"4"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf02181, Pf06346, Pf06367, Pf06371"	"1729"	"ENSG00000131504"	"DIAPH1"	"A6NF18; B7ZKW2; E9PEZ2; hsa:1729; O60610; Q17RN4; Q59FH8; Q9UC76"	"Microtubule cytoskeleton regulation; AGE/RAGE pathway; Focal adhesion; Type 2 papillary renal cell carcinoma; Regulation of actin cytoskeleton; G13 signaling pathway"	"RHOC GTPase cycle; RHOA GTPase cycle; RHO GTPases Activate Formins; RHOB GTPase cycle; RHOD GTPase cycle; RHOF GTPase cycle; Neutrophil degranulation; ERBB2 Regulates Cell Motility"	"14"	"0"	"78.3"	"69.1"	"115.1"	"106.1"	"106.8"	"142.2"	"143.0"	"118.9"	"90.4"	"148.5"	"221.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35221"	"Catenin alpha-1 OS=Homo sapiens OX=9606 GN=CTNNA1 PE=1 SV=1"	"9"	"8"	"14"	"8"	"906"	"100.0"	"6.29"	"2275.27"	"14.30"	"8"	"6"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01044"	"1495"	"ENSG00000044115"	"CTNNA1"	"hsa:1495; P35221; Q12795; Q8N1C0"	"Arrhythmogenic right ventricular cardiomyopathy; Apoptosis-related network due to altered Notch3 in ovarian cancer; VEGFA-VEGFR2 signaling; White fat cell differentiation; Endometrial cancer; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-Merlin signaling dysregulation; Pleural mesothelioma"	"RHO GTPases activate IQGAPs; Myogenesis; Adherens junctions interactions; VEGFR2 mediated vascular permeability; Regulation of CDH11 function; Regulation of CDH19 Expression and Function; CDH11 homotypic and heterotypic interactions"	"15"	"0"	"301.2"	"195.7"	"267.1"	"265.8"	"271.2"	"324.1"	"553.7"	"517.8"	"395.4"	"684.1"	"884.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52907"	"F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3"	"15"	"2"	"7"	"2"	"286"	"32.9"	"5.69"	"1030.63"	"14.28"	"1"	"2"	"cell organization and biogenesis"	"non-structural extracellular;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf01267"	"829"	"ENSG00000116489"	"CAPZA1"	"hsa:829; P52907; Q53FQ6; Q6FHD5"	""	"Advanced glycosylation endproduct receptor signaling; Sensory processing of sound by inner hair cells of the cochlea; MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Factors involved in megakaryocyte development and platelet production"	"8"	"0"	"35.1"	"21.2"	"41.1"	"45.2"	"40.1"	"48.9"	"100.2"	"90.7"	"74.6"	"148.7"	"138.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20042"	"Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2 PE=1 SV=2"	"14"	"4"	"8"	"4"	"333"	"38.4"	"5.80"	"1411.97"	"14.20"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01873"	"8894"	"ENSG00000125977"	"EIF2S2"	"hsa:8894; P20042; Q9BVU0; Q9UJE4"	"Translation factors; Brain-derived neurotrophic factor (BDNF) signaling pathway; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell; Primary ovarian insufficiency"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; ABC-family proteins mediated transport; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK1 (HRI) to heme deficiency; PERK regulates gene expression; Recycling of eIF2:GDP; Response of EIF2AK4 (GCN2) to amino acid deficiency"	"14"	"0"	"102.0"	"72.1"	"100.4"	"84.0"	"87.5"	"92.6"	"377.0"	"405.5"	"313.8"	"618.5"	"1044.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31150"	"Rab GDP dissociation inhibitor alpha OS=Homo sapiens OX=9606 GN=GDI1 PE=1 SV=2"	"9"	"4"	"9"	"1"	"447"	"50.6"	"5.14"	"1317.79"	"14.19"	"3"	"4"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00996"	"2664"	"ENSG00000203879"	"GDI1"	"hsa:2664; P31150; P50394; Q6FG50; Q7Z2G6; Q7Z2G9; Q7Z2H5; Q7Z2I6"	"Ciliary landscape; Airway smooth muscle cell contraction"	"RAB GEFs exchange GTP for GDP on RABs"	"3"	"0"	"39.6"	"26.7"	"53.1"	"30.4"	"32.3"	"38.2"	"62.4"	"53.9"	"38.8"	"71.2"	"87.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6PKG0"	"La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2"	"5"	"5"	"9"	"5"	"1096"	"123.4"	"8.82"	"1465.10"	"14.18"	"4"	"5"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf05383"	"23367"	"ENSG00000155506"	"LARP1"	"hsa:23367; O94836; Q6PKG0; Q8N4M2; Q8NB73; Q9UFD7"	"Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins; SARS-CoV-2 innate immunity evasion and cell-specific immune response; Network map of SARS-CoV-2 signaling pathway"	"SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"4"	"0"	"252.8"	"163.9"	"222.0"	"189.8"	"230.0"	"234.8"	"518.3"	"455.3"	"301.4"	"489.5"	"614.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02543"	"60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2"	"23"	"4"	"8"	"4"	"176"	"20.7"	"10.71"	"1469.88"	"14.18"	"4"	"4"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01775"	"6142"	"ENSG00000105640"	"RPL18A"	"hsa:6142; Q02543"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"179.8"	"123.3"	"180.5"	"154.2"	"178.8"	"192.7"	"534.9"	"490.8"	"376.9"	"607.1"	"700.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15369"	"Elongin-C OS=Homo sapiens OX=9606 GN=ELOC PE=1 SV=1"	"36"	"3"	"8"	"3"	"112"	"12.5"	"4.78"	"1463.34"	"14.17"	"3"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf03931"	"6921"	"ENSG00000154582"	"ELOC"	"E5RGD9; hsa:6921; Q15369; Q567Q6"	"Dual hijack model of Vif in HIV infection; VEGFA-VEGFR2 signaling; Type 2 papillary renal cell carcinoma; Hijack of ubiquitination by SARS-CoV-2"	"Regulation of expression of SLITs and ROBOs; Antigen processing: Ubiquitination & Proteasome degradation; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Vif-mediated degradation of APOBEC3G; Neddylation; Inactivation of CSF3 (G-CSF) signaling; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes"	"21"	"0"	"140.8"	"134.3"	"135.2"	"157.6"	"125.7"	"161.5"	"214.9"	"244.8"	"220.3"	"310.0"	"366.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q53F19"	"Nuclear cap-binding protein subunit 3 OS=Homo sapiens OX=9606 GN=NCBP3 PE=1 SV=2"	"10"	"6"	"11"	"6"	"620"	"70.5"	"5.73"	"1915.99"	"14.16"	"6"	"5"	"RNA metabolism OR transcription;other metabolic processes;stress response;transport"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf10309"	"55421"	"ENSG00000074356"	"NCBP3"	"B3KWG7; hsa:55421; Q53F19; Q7L406; Q96FK1; Q9NXZ4"	""	""	"0"	"0"	"390.3"	"259.8"	"336.3"	"323.4"	"351.7"	"421.8"	"778.2"	"766.2"	"713.8"	"1113.8"	"2067.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62857"	"40S ribosomal protein S28 OS=Homo sapiens OX=9606 GN=RPS28 PE=1 SV=1"	"36"	"3"	"10"	"3"	"69"	"7.8"	"10.70"	"1974.26"	"14.13"	"3"	"3"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01200"	"6234"	"ENSG00000233927"	"RPS28"	"hsa:6234; P25112; P62857"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"356.3"	"247.2"	"329.6"	"274.8"	"304.5"	"308.6"	"1078.4"	"1057.1"	"761.8"	"995.3"	"1040.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BZ29"	"Dedicator of cytokinesis protein 9 OS=Homo sapiens OX=9606 GN=DOCK9 PE=1 SV=2"	"3"	"4"	"8"	"4"	"2069"	"236.3"	"7.49"	"1547.96"	"14.10"	"4"	"4"	"signal transduction;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity"	"Pf00169, Pf06920, Pf11878, Pf14429, Pf20421, Pf20422"	"23348"	"ENSG00000088387"	"DOCK9"	"B3KX25; E9PFM9; hsa:23348; Q5JUD4; Q5JUD6; Q5T2Q1; Q5TAN8; Q9BZ25; Q9BZ26; Q9BZ27; Q9BZ28; Q9BZ29; Q9UPU4"	""	"Factors involved in megakaryocyte development and platelet production; CDC42 GTPase cycle; RAC1 GTPase cycle"	"3"	"0"	"22.4"	"14.5"	"31.5"	"25.7"	"29.8"	"34.0"	"74.8"	"110.5"	"187.9"	"341.8"	"299.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18077"	"60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2"	"36"	"6"	"11"	"6"	"110"	"12.5"	"11.06"	"1809.14"	"14.09"	"6"	"5"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01247"	"6165"	"ENSG00000182899"	"RPL35A"	"hsa:6165; P18077; Q08ES9; Q9BVN7"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"778.0"	"450.3"	"686.5"	"579.9"	"722.0"	"643.4"	"2284.9"	"1964.1"	"1386.4"	"2626.1"	"3262.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14868"	"Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2"	"10"	"4"	"9"	"4"	"501"	"57.1"	"6.55"	"1506.62"	"14.01"	"4"	"4"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00152, Pf01336"	"1615"	"ENSG00000115866"	"DARS1"	"A8K3J2; D3DP77; hsa:1615; P14868; Q2TNI3; Q32Q69; Q53HV4; Q53YC5; Q68CR9; Q9BW52"	"Alanine and aspartate metabolism"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"3"	"0"	"77.0"	"54.9"	"67.2"	"57.7"	"60.7"	"76.9"	"95.5"	"104.3"	"56.2"	"130.2"	"170.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"E9PAV3"	"Nascent polypeptide-associated complex subunit alpha, muscle-specific form OS=Homo sapiens OX=9606 GN=NACA PE=1 SV=1"	"2"	"3"	"8"	"3"	"2078"	"205.3"	"9.58"	"1613.51"	"14.00"	"3"	"3"	"transport"	"translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01849, Pf19026"	""	"ENSG00000196531"	"NACA"	"E9PAV3"	""	""	"0"	"0"	"181.6"	"109.6"	"189.0"	"180.1"	"170.7"	"177.8"	"577.9"	"452.9"	"269.3"	"448.3"	"420.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NDT2"	"Putative RNA-binding protein 15B OS=Homo sapiens OX=9606 GN=RBM15B PE=1 SV=3"	"5"	"3"	"8"	"2"	"890"	"97.1"	"9.85"	"1520.54"	"13.98"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf07744"	"29890"	"ENSG00000259956"	"RBM15B"	"A4QPG7; hsa:29890; Q6QE19; Q8NDT2; Q9BV96"	""	""	"0"	"0"	"19.9"	"12.8"	"23.8"	"19.6"	"31.5"	"26.1"	"77.7"	"113.7"	"150.1"	"297.2"	"447.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15181"	"Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2"	"21"	"4"	"7"	"4"	"289"	"32.6"	"5.86"	"1117.80"	"13.87"	"3"	"4"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00719"	"5464"	"ENSG00000180817"	"PPA1"	"hsa:5464; Q15181; Q2M348; Q5SQT7; Q6P7P4; Q9UQJ5; Q9Y5B1"	""	"Cytosolic tRNA aminoacylation; Pyrophosphate hydrolysis"	"2"	"0"	"232.2"	"132.1"	"198.2"	"122.0"	"179.5"	"189.0"	"248.1"	"208.1"	"187.6"	"350.0"	"773.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BS26"	"Endoplasmic reticulum resident protein 44 OS=Homo sapiens OX=9606 GN=ERP44 PE=1 SV=1"	"11"	"5"	"10"	"4"	"406"	"46.9"	"5.26"	"1440.47"	"13.84"	"5"	"5"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf00085, Pf13848"	"23071"	"ENSG00000023318"	"ERP44"	"hsa:23071; O60319; Q4VXC1; Q5VWZ7; Q6UW14; Q8WX67; Q9BS26"	""	"Neutrophil degranulation"	"1"	"1"	"383.9"	"269.4"	"361.1"	"369.0"	"363.6"	"414.2"	"562.0"	"592.3"	"596.9"	"795.1"	"1267.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96SB3"	"Neurabin-2 OS=Homo sapiens OX=9606 GN=PPP1R9B PE=1 SV=3"	"5"	"4"	"8"	"3"	"817"	"89.3"	"4.97"	"957.30"	"13.83"	"2"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;kinase activity;other molecular function"	"Pf00595, Pf17817"	"84687"	"ENSG00000108819"	"PPP1R9B"	"D3DTX6; hsa:84687; Q8TCR9; Q96SB3"	""	""	"0"	"0"	"127.4"	"69.8"	"118.2"	"117.2"	"98.9"	"132.0"	"247.6"	"244.2"	"158.1"	"233.0"	"306.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43809"	"Cleavage and polyadenylation specificity factor subunit 5 OS=Homo sapiens OX=9606 GN=NUDT21 PE=1 SV=1"	"18"	"4"	"9"	"4"	"227"	"26.2"	"8.82"	"1552.20"	"13.69"	"4"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13869"	"11051"	"ENSG00000167005"	"NUDT21"	"hsa:11051; O43809; Q6IB85; Q6NE84"	"mRNA processing"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"5"	"0"	"484.4"	"318.0"	"370.6"	"338.7"	"367.4"	"427.8"	"927.8"	"805.0"	"615.6"	"916.1"	"1177.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NI27"	"THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2"	"2"	"4"	"10"	"4"	"1593"	"182.7"	"8.44"	"1646.26"	"13.68"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf11262, Pf11732, Pf16134"	"57187"	"ENSG00000125676"	"THOC2"	"A6NM50; hsa:57187; Q5JZ12; Q6IN92; Q8NI27; Q9H8I6"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"3"	"0"	"479.4"	"346.3"	"440.8"	"404.2"	"448.5"	"516.8"	"1053.5"	"937.2"	"706.6"	"1291.2"	"1730.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5JWF2"	"Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas OS=Homo sapiens OX=9606 GN=GNAS PE=1 SV=2"	"5"	"5"	"9"	"4"	"1037"	"111.0"	"5.03"	"1145.45"	"13.67"	"4"	"5"	"cell adhesion;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00503"	"2778"	"ENSG00000087460"	"GNAS"	"A2A2S3; E1P5G3; O75684; O75685; Q5JW67; Q5JWF1; Q5JWF2; Q9NY42"	"Thyroid stimulating hormone (TSH) signaling pathway; Endothelin pathways; Corticotropin-releasing hormone signaling pathway; Common pathways underlying drug addiction; Myometrial relaxation and contraction pathways; G protein signaling pathways; Thermogenesis; Hippo signaling regulation pathways; Purinergic signaling; GPR143 in melanocytes and retinal pigment epithelium cells; Prostaglandin and leukotriene metabolism in senescence ; Primary ovarian insufficiency; Prostaglandin and leukotriene metabolism in senescence ; Calcium regulation in cardiac cells; Estrogen signaling pathway; Serotonin receptor 4/6/7 and NR3C signaling"	"G alpha (i) signalling events; G alpha (z) signalling events; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Prostacyclin signalling through prostacyclin receptor; Glucagon-type ligand receptors; Vasopressin regulates renal water homeostasis via Aquaporins; PKA activation in glucagon signalling; Hedgehog 'off' state"	"28"	"0"	"221.0"	"133.0"	"175.0"	"188.8"	"190.7"	"209.9"	"343.4"	"291.0"	"219.2"	"336.9"	"437.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55769"	"NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3"	"32"	"4"	"6"	"4"	"128"	"14.2"	"8.46"	"1124.10"	"13.66"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01248"	"4809"	"ENSG00000100138"	"SNU13"	"hsa:4809; P55769"	"mRNA processing"	"mRNA Splicing - Major Pathway; Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"4"	"0"	"146.7"	"106.7"	"138.5"	"163.4"	"144.0"	"170.8"	"372.9"	"385.1"	"378.3"	"769.1"	"1225.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62910"	"60S ribosomal protein L32 OS=Homo sapiens OX=9606 GN=RPL32 PE=1 SV=2"	"33"	"4"	"10"	"4"	"135"	"15.9"	"11.33"	"1491.97"	"13.65"	"4"	"4"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01655"	"6161"	"ENSG00000144713"	"RPL32"	"B2R4Q3; hsa:6161; P02433; P62910"	"Cytoplasmic ribosomal proteins"	"SRP-dependent cotranslational protein targeting to membrane; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"204.2"	"144.5"	"166.4"	"159.8"	"189.1"	"197.1"	"590.5"	"576.1"	"441.4"	"625.9"	"710.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13263"	"Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5"	"6"	"5"	"9"	"5"	"835"	"88.5"	"5.77"	"1395.09"	"13.60"	"4"	"5"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00628, Pf00643, Pf14634"	"10155"	"ENSG00000130726"	"TRIM28"	"hsa:10155; O00677; Q13263; Q7Z632; Q93040; Q96IM1"	"Corticotropin-releasing hormone signaling pathway; Mesodermal commitment pathway; ATM signaling in development and disease"	"HCMV Early Events; SUMOylation of transcription cofactors; Generic Transcription Pathway"	"6"	"0"	"606.6"	"387.9"	"467.4"	"435.1"	"495.3"	"636.8"	"864.5"	"734.4"	"537.5"	"962.7"	"1278.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75689"	"Arf-GAP with dual PH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ADAP1 PE=1 SV=2"	"18"	"5"	"9"	"4"	"374"	"43.4"	"8.97"	"1633.56"	"13.60"	"5"	"4"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf01412"	"11033"	"ENSG00000105963"	"ADAP1"	"A4D2Q2; B3KRZ4; B4DVA6; F6XZ68; H7C2Q4; hsa:11033; O75689"	""	"Nuclear signaling by ERBB4"	"1"	"1"	"69.9"	"50.0"	"76.4"	"91.4"	"99.9"	"111.5"	"334.5"	"303.7"	"381.1"	"988.6"	"1555.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75340"	"Programmed cell death protein 6 OS=Homo sapiens OX=9606 GN=PDCD6 PE=1 SV=1"	"26"	"3"	"7"	"3"	"191"	"21.9"	"5.40"	"958.57"	"13.59"	"2"	"3"	"cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf13202, Pf13499"	"10016"	"ENSG00000249915"	"PDCD6"	"B2RD16; E7ESR3; hsa:10016; O75340; Q2YDC2; Q5TZS0"	"Epithelial to mesenchymal transition in colorectal cancer"	""	"1"	"0"	"86.6"	"50.9"	"103.6"	"73.8"	"75.1"	"93.3"	"141.2"	"143.6"	"107.0"	"163.6"	"224.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P36954"	"DNA-directed RNA polymerase II subunit RPB9 OS=Homo sapiens OX=9606 GN=POLR2I PE=1 SV=1"	"38"	"4"	"5"	"4"	"125"	"14.5"	"5.14"	"389.58"	"13.57"	"1"	"4"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01096, Pf02150"	"5438"	"ENSG00000105258"	"POLR2I"	"B2R5J2; hsa:5438; P36954; Q6NW05"	"Pyrimidine metabolism; Eukaryotic transcription initiation"	"mRNA Splicing - Major Pathway; Transcriptional regulation by small RNAs; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Inhibition of DNA recombination at telomere; PIWI-interacting RNA (piRNA) biogenesis; Processing of Capped Intron-Containing Pre-mRNA; Viral Messenger RNA Synthesis; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; MicroRNA (miRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Signaling by FGFR2 IIIa TM"	"43"	"0"	"213.4"	"176.0"	"218.1"	"221.5"	"196.9"	"279.5"	"604.6"	"600.3"	"471.9"	"623.8"	"632.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P27797"	"Calreticulin OS=Homo sapiens OX=9606 GN=CALR PE=1 SV=1"	"18"	"6"	"8"	"6"	"417"	"48.1"	"4.44"	"1129.14"	"13.52"	"4"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;extracellular matrix;plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00262"	"811"	"ENSG00000179218"	"CALR"	"hsa:811; P27797; Q6IAT4; Q9UDG2"	"Androgen receptor signaling pathway; Complement system; Photodynamic therapy-induced unfolded protein response; VEGFA-VEGFR2 signaling; GDNF signaling; Calcium regulation in cardiac cells"	"ER-Phagosome pathway; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Scavenging by Class A Receptors; Assembly of Viral Components at the Budding Site; Scavenging by Class F Receptors; ATF6 (ATF6-alpha) activates chaperone genes; Calnexin/calreticulin cycle"	"13"	"0"	"738.4"	"400.4"	"706.2"	"478.6"	"634.7"	"616.7"	"1075.9"	"897.0"	"667.6"	"1053.9"	"1435.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12769"	"Nuclear pore complex protein Nup160 OS=Homo sapiens OX=9606 GN=NUP160 PE=1 SV=3"	"3"	"4"	"8"	"4"	"1436"	"162.0"	"5.50"	"1469.07"	"13.49"	"4"	"4"	"other metabolic processes;transport;developmental processes"	"cytosol;nucleus"	"other molecular function"	"Pf11715"	"23279"	"ENSG00000030066"	"NUP160"	"B4DYE8; B4E2J9; hsa:23279; Q08AD3; Q12769; Q7Z5X6; Q96GB3; Q9H660"	""	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; HCMV Early Events; EML4 and NUDC in mitotic spindle formation; Rev-mediated nuclear export of HIV RNA; Nuclear import of Rev protein; Postmitotic nuclear pore complex (NPC) reformation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; HCMV Late Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"35"	"0"	"221.0"	"134.4"	"197.5"	"206.9"	"216.1"	"234.0"	"392.6"	"381.0"	"252.7"	"369.2"	"436.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3U8"	"60S ribosomal protein L36 OS=Homo sapiens OX=9606 GN=RPL36 PE=1 SV=3"	"30"	"5"	"9"	"5"	"105"	"12.2"	"11.59"	"1658.04"	"13.46"	"5"	"4"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus"	"other molecular function"	"Pf01158"	"25873"	"ENSG00000130255"	"RPL36"	"B2R4Y1; D6W634; hsa:25873; Q6FIG1; Q9UQF6; Q9Y3U8"	"Cytoplasmic ribosomal proteins"	"Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"202.7"	"144.0"	"170.6"	"152.0"	"172.2"	"194.5"	"610.2"	"613.9"	"453.4"	"775.5"	"747.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H2U1"	"ATP-dependent DNA/RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2"	"6"	"5"	"10"	"5"	"1008"	"114.7"	"7.68"	"1804.18"	"13.45"	"5"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"170506"	"ENSG00000174953"	"DHX36"	"B2RB00; hsa:170506; Q70JU3; Q8IYE5; Q9H2U1; Q9P240"	"VEGFA-VEGFR2 signaling"	"DEx/H-box helicases activate type I IFN and inflammatory cytokines production"	"2"	"0"	"323.0"	"178.6"	"266.6"	"271.3"	"294.3"	"268.0"	"542.2"	"544.1"	"390.5"	"670.4"	"1000.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q05519"	"Serine/arginine-rich splicing factor 11 OS=Homo sapiens OX=9606 GN=SRSF11 PE=1 SV=1"	"12"	"5"	"10"	"5"	"484"	"53.5"	"10.52"	"1542.29"	"13.42"	"5"	"5"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00076"	"9295"	"ENSG00000116754"	"SRSF11"	"hsa:9295; Q05519; Q5T758; Q8IWE6"	""	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"5"	"0"	"357.2"	"230.8"	"283.6"	"311.8"	"314.0"	"346.1"	"673.4"	"525.4"	"335.3"	"560.8"	"807.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q07157"	"Tight junction protein ZO-1 OS=Homo sapiens OX=9606 GN=TJP1 PE=1 SV=3"	"3"	"5"	"8"	"5"	"1748"	"195.3"	"6.70"	"1419.11"	"13.40"	"4"	"4"	"cell adhesion;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00595, Pf00625, Pf00791, Pf07653"	"7082"	"ENSG00000104067; ENSG00000277401"	"TJP1"	"B4E3K1; hsa:7082; Q07157; Q2NKP3; Q4ZGJ6"	"Epithelial to mesenchymal transition in colorectal cancer; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Gastrin signaling pathway; Disruption of postsynaptic signaling by CNV; 1q21.1 copy number variation syndrome; CKAP4 signaling pathway map; 15q11q13 copy number variation"	"RUNX1 regulates expression of components of tight junctions; Signaling by Hippo; Regulation of gap junction activity; SARS-CoV-2 targets PDZ proteins in cell-cell junction; Apoptotic cleavage of cell adhesion  proteins"	"12"	"0"	"186.8"	"144.2"	"171.4"	"161.5"	"164.9"	"211.7"	"445.9"	"411.6"	"360.4"	"500.9"	"585.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13547"	"Histone deacetylase 1 OS=Homo sapiens OX=9606 GN=HDAC1 PE=1 SV=1"	"11"	"5"	"9"	"5"	"482"	"55.1"	"5.48"	"2023.02"	"13.36"	"4"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00850"	"3065"	"ENSG00000116478"	"HDAC1"	"hsa:3065; Q13547; Q92534"	"Androgen receptor signaling pathway; Energy metabolism; Cell cycle; TNF-related weak inducer of apoptosis (TWEAK) signaling pathway; Neural crest differentiation; Retinoblastoma gene in cancer; Notch signaling; Apoptosis-related network due to altered Notch3 in ovarian cancer; Initiation of transcription and translation elongation at the HIV-1 LTR; MECP2 and associated Rett syndrome; IL6 signaling pathway; Valproic acid pathway; VEGFA-VEGFR2 signaling; Ethanol effects on histone modifications; Rett syndrome causing genes; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; Ciliary landscape; Transcription co-factors SKI and SKIL protein partners; Overlap between signal transduction pathways contributing to LMNA laminopathies; Opioid receptor pathways; 15q11q13 copy number variation; Notch signaling pathway; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Potential therapeutics for SARS; Estrogen-dependent gene expression; Downregulation of SMAD2/3:SMAD4 transcriptional activity; Formation of the beta-catenin:TCF transactivating complex; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; SUMOylation of chromatin organization proteins; Regulation of PTEN gene transcription; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes; SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Deactivation of the beta-catenin transactivating complex; MECP2 regulates transcription of neuronal ligands; Factors involved in megakaryocyte development and platelet production; RNA Polymerase I Transcription Initiation; p75NTR negatively regulates cell cycle via SC1; NOTCH1 Intracellular Domain Regulates Transcription; Notch-HLH transcription pathway; Regulation of MECP2 expression and activity; STAT3 nuclear events downstream of ALK signaling; G1/S-Specific Transcription; Regulation of TP53 Activity through Acetylation; Transcription of E2F targets under negative control by DREAM complex; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1; MECP2 regulates neuronal receptors and channels; Repression of WNT target genes; Loss of MECP2 binding ability to 5mC-DNA"	"54"	"0"	"671.4"	"408.4"	"602.4"	"566.4"	"563.8"	"705.6"	"1057.1"	"939.3"	"679.1"	"1078.4"	"1550.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13825"	"Methylglutaconyl-CoA hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=AUH PE=1 SV=1"	"12"	"3"	"7"	"3"	"339"	"35.6"	"9.48"	"1075.25"	"13.34"	"2"	"3"	"other metabolic processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00378"	"549"	"ENSG00000148090"	"AUH"	"B1ALV7; B1ALV8; hsa:549; Q13825; Q8WUE4"	"Amino acid metabolism"	"Branched-chain amino acid catabolism"	"2"	"0"	"43.5"	"31.8"	"45.8"	"41.7"	"47.0"	"47.6"	"293.4"	"324.7"	"362.3"	"643.5"	"839.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19447"	"General transcription and DNA repair factor IIH helicase subunit XPB OS=Homo sapiens OX=9606 GN=ERCC3 PE=1 SV=1"	"6"	"4"	"6"	"4"	"782"	"89.2"	"7.23"	"644.64"	"13.32"	"2"	"4"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04851, Pf13625, Pf16203"	"2071"	"ENSG00000163161"	"ERCC3"	"hsa:2071; P19447; Q53QM0"	"Eukaryotic transcription initiation; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; Formation of Incision Complex in GG-NER; Dual Incision in GG-NER"	"33"	"0"	"38.3"	"27.6"	"37.5"	"41.0"	"39.2"	"48.0"	"125.2"	"226.7"	"236.0"	"443.7"	"511.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14204"	"Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5"	"1"	"5"	"9"	"5"	"4646"	"532.1"	"6.40"	"1115.26"	"13.32"	"4"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03028, Pf08385, Pf08393, Pf12774, Pf12775, Pf12777, Pf12780, Pf12781, Pf17852, Pf18198, Pf18199"	"1778"	"ENSG00000197102"	"DYNC1H1"	"B0I1R0; hsa:1778; Q14204; Q6DKQ7; Q8WU28; Q92814; Q9Y4G5"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; PAFAH1B1 copy number variation"	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Neutrophil degranulation; HCMV Early Events; Separation of Sister Chromatids; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; Recruitment of NuMA to mitotic centrosomes; RHO GTPases Activate Formins; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Aggrephagy; EML4 and NUDC in mitotic spindle formation; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"23"	"0"	"84.2"	"61.7"	"81.6"	"76.1"	"82.2"	"86.6"	"137.2"	"114.0"	"90.5"	"159.3"	"230.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61218"	"DNA-directed RNA polymerases I, II, and III subunit RPABC2 OS=Homo sapiens OX=9606 GN=POLR2F PE=1 SV=1"	"33"	"4"	"7"	"4"	"127"	"14.5"	"4.22"	"831.79"	"13.32"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01192"	"5435"	"ENSG00000100142"	"POLR2F"	"hsa:5435; P41584; P61218; Q6IAY3"	"Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"mRNA Splicing - Major Pathway; RNA polymerase II transcribes snRNA genes; Processing of Capped Intron-Containing Pre-mRNA; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; B-WICH complex positively regulates rRNA expression; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"56"	"0"	"296.2"	"154.5"	"224.3"	"228.0"	"214.6"	"285.4"	"459.6"	"535.3"	"516.5"	"788.3"	"1088.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15427"	"Splicing factor 3B subunit 4 OS=Homo sapiens OX=9606 GN=SF3B4 PE=1 SV=1"	"12"	"4"	"9"	"4"	"424"	"44.4"	"8.56"	"1696.54"	"13.27"	"4"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00076"	"10262"	"ENSG00000143368"	"SF3B4"	"hsa:10262; Q15427; Q5SZ63"	"mRNA processing; 10q22q23 copy number variation"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"4"	"0"	"284.0"	"196.1"	"266.3"	"249.0"	"285.5"	"276.5"	"703.2"	"699.1"	"467.8"	"825.4"	"952.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53680"	"AP-2 complex subunit sigma OS=Homo sapiens OX=9606 GN=AP2S1 PE=1 SV=2"	"27"	"4"	"11"	"4"	"142"	"17.0"	"6.18"	"1694.04"	"13.26"	"4"	"3"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01217"	"1175"	"ENSG00000042753"	"AP2S1"	"B2R4Z4; hsa:1175; O75977; P53680; Q6PK67"	"Synaptic vesicle pathway; VEGFA-VEGFR2 signaling; GABA receptor signaling; EGF/EGFR signaling pathway; Fragile X syndrome"	"MHC class II antigen presentation; Potential therapeutics for SARS; Recycling pathway of L1; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; LDL clearance; Nef Mediated CD4 Down-regulation; Retrograde neurotrophin signalling; Nef Mediated CD8 Down-regulation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation"	"18"	"0"	"53.3"	"37.7"	"71.9"	"75.0"	"83.2"	"72.1"	"235.9"	"429.9"	"741.8"	"1431.6"	"1898.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51858"	"Hepatoma-derived growth factor OS=Homo sapiens OX=9606 GN=HDGF PE=1 SV=1"	"22"	"4"	"7"	"4"	"240"	"26.8"	"4.73"	"1367.01"	"13.26"	"3"	"4"	"cell organization and biogenesis;signal transduction;other biological processes"	"nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00855"	"3068"	"ENSG00000143321"	"HDGF"	"B3KU21; D3DVC9; hsa:3068; P51858; Q5SZ07; Q5SZ08; Q5SZ09"	"IL-18 signaling pathway"	"XBP1(S) activates chaperone genes"	"2"	"0"	"252.3"	"155.1"	"216.8"	"162.5"	"205.7"	"217.0"	"406.0"	"337.6"	"253.1"	"409.9"	"514.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BZK7"	"F-box-like/WD repeat-containing protein TBL1XR1 OS=Homo sapiens OX=9606 GN=TBL1XR1 PE=1 SV=1"	"10"	"4"	"8"	"2"	"514"	"55.6"	"5.55"	"1457.14"	"13.26"	"4"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400, Pf08513"	"79718"	"ENSG00000177565"	"TBL1XR1"	"D3DNQ9; hsa:79718; Q14DC3; Q9BZK7; Q9H2I1; Q9H9A1"	"Rett syndrome causing genes"	"Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; NOTCH1 Intracellular Domain Regulates Transcription; HCMV Early Events; PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; Heme signaling; BMAL1:CLOCK,NPAS2 activates circadian gene expression; Transcriptional activation of mitochondrial biogenesis; HDACs deacetylate histones; Cytoprotection by HMOX1; Activation of gene expression by SREBF (SREBP); Notch-HLH transcription pathway; Loss of MECP2 binding ability to the NCoR/SMRT complex; Regulation of MECP2 expression and activity; NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux; RORA activates gene expression"	"20"	"2"	"243.2"	"141.3"	"225.1"	"222.4"	"245.3"	"269.0"	"350.7"	"327.8"	"272.9"	"390.7"	"589.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62861"	"40S ribosomal protein S30 OS=Homo sapiens OX=9606 GN=FAU PE=1 SV=1"	"19"	"2"	"10"	"2"	"59"	"6.6"	"12.15"	"1420.86"	"13.24"	"2"	"2"	"protein metabolism;other metabolic processes;stress response"	"non-structural extracellular;cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf04758"	""	"ENSCHIG00000017446; ENSJHYG00000000624; ENSLLEG00000000574"	"Fau; FAU"	"A0A452F0A8; A0A7L0YXB0; A0A8C5IE60; A0A8C5LQJ8; P0C2F0; P62860; P62863; P62864; P62866; P62867; Q05472; Q5RC12; Q8HYI8; Q920W7; Q95261"	""	""	"0"	"0"	"213.7"	"183.3"	"194.8"	"172.6"	"201.6"	"202.3"	"523.0"	"548.1"	"496.7"	"556.8"	"653.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UK45"	"U6 snRNA-associated Sm-like protein LSm7 OS=Homo sapiens OX=9606 GN=LSM7 PE=1 SV=1"	"48"	"4"	"9"	"4"	"103"	"11.6"	"5.27"	"1163.66"	"13.22"	"3"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	"51690"	"ENSG00000130332"	"LSM7"	"hsa:51690; Q9UK45"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease"	"3"	"0"	"1138.8"	"683.2"	"851.0"	"681.3"	"823.7"	"871.0"	"1828.5"	"1573.8"	"1262.2"	"2037.2"	"2743.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2W2"	"WW domain-binding protein 11 OS=Homo sapiens OX=9606 GN=WBP11 PE=1 SV=1"	"7"	"4"	"8"	"4"	"641"	"70.0"	"8.38"	"1536.87"	"13.20"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09429"	"51729"	"ENSG00000084463"	"WBP11"	"hsa:51729; Q96AY8; Q9Y2W2"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"136.3"	"106.3"	"127.0"	"113.1"	"114.6"	"148.4"	"268.5"	"239.0"	"184.8"	"338.3"	"363.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BWJ5"	"Splicing factor 3B subunit 5 OS=Homo sapiens OX=9606 GN=SF3B5 PE=1 SV=1"	"35"	"3"	"7"	"3"	"86"	"10.1"	"6.35"	"983.81"	"13.16"	"2"	"3"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf07189"	"83443"	"ENSG00000169976"	"SF3B5"	"B2R568; hsa:83443; Q7RTV1; Q9BWJ5"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"0"	"354.7"	"194.1"	"319.3"	"287.7"	"324.3"	"277.4"	"719.7"	"611.5"	"377.8"	"742.7"	"986.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UFW8"	"CGG triplet repeat-binding protein 1 OS=Homo sapiens OX=9606 GN=CGGBP1 PE=1 SV=2"	"26"	"4"	"7"	"4"	"167"	"18.8"	"8.95"	"903.83"	"13.14"	"3"	"4"	"cell organization and biogenesis;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	""	"8545"	"ENSG00000163320"	"CGGBP1"	"D3DU38; hsa:8545; O15183; Q9UFW8"	""	""	"0"	"0"	"204.8"	"127.9"	"202.3"	"176.9"	"197.8"	"222.4"	"544.7"	"470.6"	"371.6"	"568.6"	"795.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61313"	"60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2"	"21"	"4"	"9"	"4"	"204"	"24.1"	"11.62"	"1802.31"	"13.14"	"4"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00827"	"6138"	"ENSG00000174748"	"RPL15"	"hsa:6138; P39030; P41051; P61313; Q5U0C0; Q642I1; Q6IPX6; Q8WYP2; Q96C44; Q9H2E5"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"343.4"	"283.1"	"303.6"	"259.4"	"299.6"	"315.7"	"1143.6"	"1139.7"	"749.4"	"1262.9"	"1244.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NPJ3"	"Acyl-coenzyme A thioesterase 13 OS=Homo sapiens OX=9606 GN=ACOT13 PE=1 SV=1"	"25"	"3"	"7"	"3"	"140"	"15.0"	"9.14"	"1122.51"	"13.07"	"2"	"3"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;mitochondrion"	"other molecular function"	"Pf03061"	"55856"	"ENSG00000112304"	"ACOT13"	"F5H2L4; hsa:55856; O95549; Q9NPJ3"	""	"Mitochondrial Fatty Acid Beta-Oxidation"	"1"	"0"	"36.4"	"23.1"	"43.3"	"37.5"	"43.2"	"33.0"	"98.3"	"101.1"	"94.6"	"196.5"	"397.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12235"	"ADP/ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4"	"20"	"6"	"12"	"1"	"298"	"33.0"	"9.76"	"2139.94"	"13.07"	"6"	"4"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;mitochondrion"	"transporter activity"	"Pf00153"	"291"	"ENSG00000151729"	"SLC25A4"	"D3DP59; hsa:291; P12235"	"Electron transport chain: OXPHOS system in mitochondria; Alzheimer's disease and miRNA effects; Synaptic vesicle pathway; Alzheimer's disease; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane; Mitochondrial protein import; Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization"	"8"	"0"	"12.5"	"6.6"	"14.2"	"17.4"	"14.0"	"17.2"	"31.1"	"21.7"	"17.6"	"32.1"	"34.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49189"	"4-trimethylaminobutyraldehyde dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH9A1 PE=1 SV=3"	"12"	"4"	"6"	"4"	"494"	"53.8"	"5.87"	"786.58"	"13.06"	"2"	"4"	"cell organization and biogenesis;other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00171"	"223"	"ENSG00000143149"	"ALDH9A1"	"B2R6X1; B4DXY7; B9EKV4; hsa:223; P49189; Q5VV90; Q6LCL1; Q9NZT7"	"GABA receptor signaling; Fluoroacetic acid toxicity; Opioid receptor pathways"	"Carnitine synthesis"	"4"	"0"	"357.6"	"140.3"	"207.1"	"275.8"	"193.4"	"282.5"	"387.8"	"373.8"	"283.3"	"379.6"	"547.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBQ5"	"Eukaryotic translation initiation factor 3 subunit K OS=Homo sapiens OX=9606 GN=EIF3K PE=1 SV=1"	"23"	"4"	"7"	"4"	"218"	"25.0"	"4.93"	"1648.35"	"12.99"	"4"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf10075"	"27335"	"ENSG00000178982; ENSG00000282986"	"EIF3K"	"A8K0I9; B7ZAM9; hsa:27335; Q96IQ0; Q9UBQ5; Q9Y6D1"	""	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"6"	"0"	"582.8"	"319.3"	"480.7"	"419.7"	"466.7"	"443.8"	"858.7"	"859.2"	"673.3"	"938.1"	"1040.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14923"	"Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3"	"9"	"7"	"12"	"6"	"745"	"81.7"	"6.14"	"2185.37"	"12.94"	"7"	"5"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00514"	"3728"	"ENSG00000173801"	"JUP"	"hsa:3728; P14923; Q15093; Q15151; Q7L3S5; Q86W21; Q9BWC4; Q9HCX9"	"Arrhythmogenic right ventricular cardiomyopathy; Corticotropin-releasing hormone signaling pathway; Ectoderm differentiation; Ectoderm differentiation; Epithelial to mesenchymal transition in colorectal cancer; Opioid receptor pathways"	"RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RHOB GTPase cycle; Formation of the cornified envelope; RHOQ GTPase cycle; RHOJ GTPase cycle; Neutrophil degranulation; VEGFR2 mediated vascular permeability; Adherens junctions interactions; Regulation of CDH11 function; Regulation of CDH19 Expression and Function; CDH11 homotypic and heterotypic interactions; RHOH GTPase cycle"	"21"	"1"	"453.8"	"254.2"	"956.1"	"330.1"	"411.3"	"453.3"	"622.8"	"567.8"	"426.3"	"720.5"	"912.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13310"	"Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1"	"7"	"4"	"8"	"2"	"644"	"70.7"	"9.26"	"1417.73"	"12.94"	"4"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf00658"	"8761"	"ENSG00000090621"	"PABPC4"	"B1ANQ8; hsa:8761; Q13310; Q4VC03; Q6P0N3"	""	""	"0"	"0"	"170.3"	"111.1"	"140.3"	"128.4"	"163.6"	"166.2"	"330.7"	"281.2"	"232.0"	"374.5"	"438.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15226"	"NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2"	"7"	"4"	"8"	"4"	"690"	"77.6"	"8.79"	"1661.06"	"12.93"	"4"	"4"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01424, Pf01585"	"55922"	"ENSG00000186416"	"NKRF"	"G3V1N1; hsa:55922; O15226; Q4VC41; Q9UJ91"	"Pathogenesis of SARS-CoV-2 mediated by nsp9-nsp10 complex; Network map of SARS-CoV-2 signaling pathway"	""	"2"	"0"	"236.9"	"150.7"	"188.6"	"183.3"	"230.1"	"231.1"	"511.0"	"453.6"	"305.2"	"551.5"	"805.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07196"	"Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3"	"8"	"4"	"10"	"3"	"543"	"61.5"	"4.65"	"1756.96"	"12.92"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00038, Pf04732"	"4747"	"ENSG00000277586"	"NEFL"	"B9ZVN2; hsa:4747; P07196; Q16154; Q8IU72"	"Amyotrophic lateral sclerosis (ALS); Physico-chemical features and toxicity-associated pathways; NO/cGMP/PKG mediated neuroprotection; Ciliary landscape; Intracellular trafficking proteins involved in CMT neuropathy; CCL18 signaling pathway"	"Assembly and cell surface presentation of NMDA receptors; RAF/MAP kinase cascade; Ras activation upon Ca2+ influx through NMDA receptor; Unblocking of NMDA receptors, glutamate binding and activation; Negative regulation of NMDA receptor-mediated neuronal transmission; Long-term potentiation"	"12"	"0"	"180.2"	"106.4"	"138.8"	"149.9"	"174.8"	"186.7"	"198.7"	"176.5"	"143.7"	"227.3"	"296.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P15311"	"Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4"	"8"	"5"	"10"	"5"	"586"	"69.4"	"6.27"	"1533.84"	"12.91"	"5"	"5"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf00769, Pf09379, Pf09380, Pf20492"	"7430"	"ENSG00000092820"	"EZR"	"E1P5A8; hsa:7430; P15311; P23714; Q4VX75; Q96CU8; Q9NSJ4"	"Pathogenic Escherichia coli infection; AGE/RAGE pathway; VEGFA-VEGFR2 signaling; 16p11.2 proximal deletion syndrome; CCL18 signaling pathway; Regulation of actin cytoskeleton; GDNF signaling"	"Recycling pathway of L1; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Netrin-1 signaling"	"11"	"0"	"170.7"	"105.7"	"179.1"	"179.8"	"191.8"	"177.4"	"955.4"	"794.1"	"608.6"	"1295.3"	"1858.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49458"	"Signal recognition particle 9 kDa protein OS=Homo sapiens OX=9606 GN=SRP9 PE=1 SV=2"	"30"	"3"	"9"	"3"	"86"	"10.1"	"7.97"	"1270.93"	"12.90"	"2"	"3"	"transport;other biological processes"	"other membranes;cytosol;ER/Golgi;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf05486"	"6726"	"ENSG00000143742"	"SRP9"	"A8K0N0; hsa:6726; P49458; Q6NVX0; Q8WTW0"	""	"SRP-dependent cotranslational protein targeting to membrane"	"1"	"0"	"107.4"	"66.9"	"94.1"	"93.8"	"105.6"	"116.7"	"525.2"	"623.5"	"634.8"	"1583.1"	"2658.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96NB3"	"Zinc finger protein 830 OS=Homo sapiens OX=9606 GN=ZNF830 PE=1 SV=2"	"13"	"4"	"6"	"3"	"372"	"42.0"	"5.31"	"611.63"	"12.89"	"2"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf12874"	"91603"	"ENSG00000198783"	"ZNF830"	"hsa:91603; Q96F60; Q96GZ5; Q96NB3; Q9BU38"	"17q12 copy number variation syndrome"	"mRNA Splicing - Major Pathway; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	"6"	"0"	"56.7"	"40.4"	"44.8"	"65.3"	"53.4"	"71.5"	"209.2"	"175.5"	"167.3"	"210.4"	"260.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62917"	"60S ribosomal protein L8 OS=Homo sapiens OX=9606 GN=RPL8 PE=1 SV=2"	"16"	"6"	"10"	"6"	"257"	"28.0"	"11.03"	"1367.88"	"12.87"	"5"	"5"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00181, Pf03947"	"6132"	"ENSG00000161016"	"RPL8"	"A8K094; D3DWN2; hsa:6132; P25120; P62917; Q567Q7; Q969V7; Q9BWQ9"	"Cytoplasmic ribosomal proteins"	"Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"626.5"	"419.0"	"508.4"	"436.2"	"541.8"	"578.0"	"2168.9"	"1965.1"	"1389.3"	"2008.6"	"2349.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NV70"	"Exocyst complex component 1 OS=Homo sapiens OX=9606 GN=EXOC1 PE=1 SV=4"	"6"	"6"	"9"	"6"	"894"	"101.9"	"6.61"	"1372.03"	"12.84"	"4"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf09763, Pf15277"	"55763"	"ENSG00000090989"	"EXOC1"	"hsa:55763; Q504V4; Q8WUE7; Q96T15; Q9NV70; Q9NZE4"	"Ciliary landscape"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"4"	"0"	"299.5"	"177.6"	"288.2"	"259.3"	"298.9"	"300.2"	"887.1"	"1195.9"	"1184.4"	"1912.9"	"2525.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60832"	"H/ACA ribonucleoprotein complex subunit DKC1 OS=Homo sapiens OX=9606 GN=DKC1 PE=1 SV=3"	"6"	"2"	"6"	"2"	"514"	"57.6"	"9.42"	"1625.03"	"12.76"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01472, Pf01509, Pf08068, Pf16198"	"1736"	"ENSG00000130826"	"DKC1"	"F5BSB3; hsa:1736; O43845; O60832; Q96G67; Q9Y505"	""	"rRNA modification in the nucleus and cytosol; Telomere Extension By Telomerase"	"2"	"0"	"7.9"	"7.7"	"9.8"	"8.8"	"9.9"	"12.9"	"31.4"	"32.0"	"25.6"	"35.5"	"54.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKA9"	"Polypyrimidine tract-binding protein 2 OS=Homo sapiens OX=9606 GN=PTBP2 PE=1 SV=1"	"8"	"4"	"12"	"2"	"531"	"57.5"	"8.66"	"2668.53"	"12.73"	"4"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf11835, Pf13893"	"58155"	"ENSG00000117569"	"PTBP2"	"hsa:58155; Q8N0Z1; Q8N160; Q8NFB0; Q8NFB1; Q969N9; Q96Q76; Q9UKA9"	"Genes targeted by miRNAs in adipocytes; mRNA processing"	""	"2"	"0"	"190.2"	"98.0"	"130.7"	"134.2"	"129.8"	"155.5"	"324.9"	"337.6"	"278.2"	"417.2"	"582.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NWB6"	"Arginine and glutamate-rich protein 1 OS=Homo sapiens OX=9606 GN=ARGLU1 PE=1 SV=1"	"14"	"5"	"9"	"5"	"273"	"33.2"	"10.35"	"1202.02"	"12.70"	"4"	"5"	""	"cytosol;mitochondrion;nucleus"	""	"Pf15346"	"55082"	"ENSG00000134884"	"ARGLU1"	"B4E0Y3; hsa:55082; Q5T257; Q6IQ34; Q9NWB6"	""	""	"0"	"0"	"545.7"	"289.4"	"395.2"	"356.1"	"446.9"	"445.2"	"1045.7"	"971.5"	"683.5"	"1151.1"	"1509.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92890"	"Ubiquitin recognition factor in ER-associated degradation protein 1 OS=Homo sapiens OX=9606 GN=UFD1 PE=1 SV=3"	"20"	"4"	"6"	"4"	"307"	"34.5"	"6.70"	"674.70"	"12.70"	"2"	"4"	"protein metabolism;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf03152"	"7353"	"ENSG00000070010"	"UFD1"	"A8MW31; hsa:7353; Q92890; Q9Y5N0"	"22q11.2 copy number variation syndrome"	"Neddylation; Ub-specific processing proteases; KEAP1-NFE2L2 pathway; Translesion Synthesis by POLH"	"5"	"0"	"119.2"	"82.3"	"121.6"	"115.0"	"102.3"	"113.7"	"203.1"	"224.7"	"169.6"	"264.2"	"336.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62888"	"60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2"	"50"	"5"	"7"	"5"	"115"	"12.8"	"9.63"	"1329.22"	"12.68"	"3"	"4"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01248"	"6156"	"ENSG00000156482"	"RPL30"	"B2R591; hsa:6156; P04645; P62888; Q502Z6"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; SRP-dependent cotranslational protein targeting to membrane; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"207.9"	"143.5"	"199.4"	"164.9"	"190.0"	"200.0"	"531.5"	"483.2"	"352.9"	"561.8"	"786.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61160"	"Actin-related protein 2 OS=Homo sapiens OX=9606 GN=ACTR2 PE=1 SV=1"	"9"	"4"	"7"	"3"	"394"	"44.7"	"6.74"	"1037.63"	"12.65"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00022"	"10097"	"ENSG00000138071"	"ACTR2"	"B2RCP5; D6W5F4; E9PF41; hsa:10097; O15142; P61160; Q96C82"	"Physico-chemical features and toxicity-associated pathways; Embryonic stem cell pluripotency pathways"	"Clathrin-mediated endocytosis; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; EPHB-mediated forward signaling; Neutrophil degranulation"	"8"	"0"	"70.4"	"63.5"	"117.3"	"79.0"	"97.2"	"117.7"	"221.2"	"265.1"	"242.7"	"466.0"	"1010.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9C005"	"Protein dpy-30 homolog OS=Homo sapiens OX=9606 GN=DPY30 PE=1 SV=1"	"31"	"3"	"7"	"3"	"99"	"11.2"	"4.88"	"1659.90"	"12.64"	"3"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport"	"ER/Golgi;nucleus"	"other molecular function"	"Pf05186"	"84661"	"ENSG00000162961"	"DPY30"	"D6W578; hsa:84661; Q9C005"	"Kleefstra syndrome"	"Activation of anterior HOX genes in hindbrain development during early embryogenesis; PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Formation of WDR5-containing histone-modifying complexes"	"5"	"0"	"343.5"	"211.0"	"309.4"	"340.6"	"352.8"	"383.2"	"568.9"	"526.1"	"359.8"	"571.4"	"846.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3B4"	"Splicing factor 3B subunit 6 OS=Homo sapiens OX=9606 GN=SF3B6 PE=1 SV=1"	"22"	"3"	"9"	"3"	"125"	"14.6"	"9.38"	"1410.47"	"12.64"	"2"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"51639"	"ENSG00000115128"	"SF3B6"	"hsa:51639; Q53TM1; Q9Y3B4"	""	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"2"	"0"	"223.0"	"171.0"	"269.9"	"428.7"	"320.0"	"334.9"	"771.0"	"666.0"	"384.1"	"697.9"	"767.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P54819"	"Adenylate kinase 2, mitochondrial OS=Homo sapiens OX=9606 GN=AK2 PE=1 SV=2"	"25"	"4"	"7"	"4"	"239"	"26.5"	"7.81"	"1177.59"	"12.60"	"3"	"4"	"other metabolic processes"	"cytoskeleton;mitochondrion;other cell component"	"kinase activity;other molecular function"	"Pf00406, Pf05191"	"204"	"ENSG00000004455"	"AK2"	"A8K6L1; B4DHH7; B4DL64; hsa:204; P54819; Q16856; Q5EB54; Q5TIF7; Q8TCY2; Q8TCY3"	""	"Interconversion of nucleotide di- and triphosphates"	"1"	"0"	"71.1"	"48.9"	"77.3"	"66.9"	"74.8"	"99.0"	"113.0"	"102.8"	"81.5"	"154.8"	"227.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14818"	"Proteasome subunit alpha type-7 OS=Homo sapiens OX=9606 GN=PSMA7 PE=1 SV=1"	"18"	"4"	"9"	"4"	"248"	"27.9"	"8.46"	"1777.85"	"12.59"	"4"	"3"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00227, Pf10584"	"5688"	"ENSG00000101182"	"PSMA7"	"B2R515; hsa:5688; O14818; Q5JXJ2; Q9BR53; Q9H4K5; Q9UEU8"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"62"	"0"	"312.8"	"187.8"	"346.7"	"298.2"	"319.6"	"336.1"	"715.0"	"646.8"	"501.1"	"843.8"	"1169.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q06587"	"E3 ubiquitin-protein ligase RING1 OS=Homo sapiens OX=9606 GN=RING1 PE=1 SV=2"	"14"	"3"	"5"	"2"	"406"	"42.4"	"5.62"	"946.00"	"12.58"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00097, Pf16207"	"6015"	"ENSG00000204227; ENSG00000206287; ENSG00000226788; ENSG00000228520; ENSG00000231115; ENSG00000235107"	"RING1"	"A8JZZ0; hsa:6015; Q06587; Q5JP96; Q5SQW2; Q86V19"	"Pleural mesothelioma; Notch signaling pathway"	"Oxidative Stress Induced Senescence; SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6"	"11"	"0"	"72.7"	"47.9"	"55.0"	"70.8"	"53.1"	"90.6"	"121.8"	"100.9"	"77.2"	"113.0"	"163.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P10606"	"Cytochrome c oxidase subunit 5B, mitochondrial OS=Homo sapiens OX=9606 GN=COX5B PE=1 SV=2"	"34"	"4"	"9"	"4"	"129"	"13.7"	"8.81"	"1822.11"	"12.58"	"4"	"4"	"other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf01215"	"1329"	"ENSG00000135940"	"COX5B"	"hsa:1329; P10606; Q53YB7; Q96J18; Q99610"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly; 5q35 copy number variation"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"7"	"0"	"1189.3"	"619.2"	"708.6"	"718.0"	"712.0"	"899.8"	"1222.0"	"1056.8"	"842.0"	"1336.3"	"1628.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60739"	"Eukaryotic translation initiation factor 1b OS=Homo sapiens OX=9606 GN=EIF1B PE=1 SV=2"	"33"	"2"	"5"	"1"	"113"	"12.8"	"7.37"	"760.18"	"12.58"	"1"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"translational apparatus"	"translation activity;nucleic acid binding activity"	"Pf01253"	"10289"	"ENSG00000114784"	"EIF1B"	"hsa:10289; O60739; Q9UQF8"	""	""	"0"	"1"	"55.8"	"33.0"	"49.7"	"54.6"	"52.4"	"67.1"	"148.7"	"117.9"	"90.2"	"189.9"	"394.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49006"	"MARCKS-related protein OS=Homo sapiens OX=9606 GN=MARCKSL1 PE=1 SV=2"	"18"	"3"	"8"	"3"	"195"	"19.5"	"4.67"	"1338.01"	"12.54"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02063"	"65108"	"ENSG00000175130"	"MARCKSL1"	"D3DPQ0; hsa:65108; P49006; Q5TEE6; Q6NXS5"	""	""	"0"	"0"	"641.1"	"372.3"	"513.9"	"367.9"	"447.4"	"493.5"	"870.2"	"720.7"	"530.6"	"882.2"	"1307.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96GM8"	"Target of EGR1 protein 1 OS=Homo sapiens OX=9606 GN=TOE1 PE=1 SV=1"	"10"	"4"	"7"	"4"	"510"	"56.5"	"7.18"	"908.64"	"12.53"	"3"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00642, Pf04857"	"114034"	"ENSG00000132773"	"TOE1"	"B4DEM6; hsa:114034; Q6IA35; Q8IWN5; Q96GM8; Q9H846"	""	""	"0"	"0"	"289.6"	"201.6"	"292.3"	"248.2"	"278.4"	"266.2"	"560.2"	"540.3"	"355.5"	"477.2"	"579.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NWH9"	"SAFB-like transcription modulator OS=Homo sapiens OX=9606 GN=SLTM PE=1 SV=2"	"4"	"4"	"9"	"4"	"1034"	"117.1"	"7.87"	"1205.21"	"12.50"	"3"	"4"	"other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf02037"	"79811"	"ENSG00000137776"	"SLTM"	"A8K5V8; B2RTX3; hsa:79811; Q2VPK7; Q52MB3; Q658J7; Q6ZNF2; Q86TK6; Q9H7C3; Q9H8U9; Q9NWH9"	""	""	"0"	"0"	"160.6"	"101.8"	"132.0"	"112.0"	"132.4"	"141.4"	"455.9"	"444.9"	"378.0"	"677.7"	"994.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NP97"	"Dynein light chain roadblock-type 1 OS=Homo sapiens OX=9606 GN=DYNLRB1 PE=1 SV=3"	"42"	"3"	"8"	"3"	"96"	"10.9"	"7.25"	"1516.82"	"12.47"	"3"	"3"	"other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03259"	"83658"	"ENSG00000125971"	"DYNLRB1"	"B1AKR5; hsa:83658; Q5TC72; Q96IV3; Q9NP97; Q9NQM2"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; 3q29 copy number variation syndrome"	"Intraflagellar transport"	"4"	"0"	"184.2"	"121.4"	"182.9"	"161.1"	"177.7"	"197.9"	"268.4"	"266.0"	"191.9"	"311.1"	"443.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y224"	"RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1"	"30"	"5"	"9"	"5"	"244"	"28.1"	"6.65"	"1842.31"	"12.47"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf10036"	"51637"	"ENSG00000087302"	"RTRAF"	"hsa:51637; Q9Y224"	""	"tRNA processing in the nucleus"	"1"	"0"	"207.0"	"123.6"	"179.5"	"181.6"	"186.5"	"192.3"	"512.8"	"458.6"	"336.5"	"493.8"	"697.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13492"	"Phosphatidylinositol-binding clathrin assembly protein OS=Homo sapiens OX=9606 GN=PICALM PE=1 SV=2"	"6"	"3"	"6"	"3"	"652"	"70.7"	"7.90"	"1317.39"	"12.46"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf07651"	"8301"	"ENSG00000073921"	"PICALM"	"B4DTM3; E9PN05; F8VPG7; hsa:8301; O60700; Q13492; Q4LE54; Q6GMQ6; Q86XZ9"	""	"Cargo recognition for clathrin-mediated endocytosis; Golgi Associated Vesicle Biogenesis; RND3 GTPase cycle"	"4"	"0"	"112.9"	"70.0"	"92.1"	"97.9"	"119.8"	"121.7"	"303.0"	"348.3"	"449.7"	"975.9"	"1788.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42677"	"40S ribosomal protein S27 OS=Homo sapiens OX=9606 GN=RPS27 PE=1 SV=3"	"25"	"2"	"7"	"2"	"84"	"9.5"	"9.45"	"917.94"	"12.43"	"2"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01667"	"6232"	"ENSG00000177954"	"RPS27"	"hsa:6232; P42677; Q5T4L6"	"Cytoplasmic ribosomal proteins"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"25"	"0"	"435.9"	"344.4"	"402.8"	"361.4"	"359.7"	"403.4"	"679.2"	"625.4"	"480.2"	"736.0"	"984.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P45880"	"Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2"	"18"	"4"	"8"	"4"	"294"	"31.5"	"7.56"	"1326.40"	"12.38"	"4"	"4"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"other membranes;cytoskeleton;mitochondrion;other cell component"	"transporter activity;other molecular function"	"Pf01459"	"7417"	"ENSG00000165637"	"VDAC2"	"hsa:7417; P45880; Q5VWK1; Q5VWK3; Q6IB40; Q7L3J5; Q9BWK8; Q9Y5I6"	"Alzheimer's disease and miRNA effects; Ferroptosis; Alzheimer's disease"	"Ub-specific processing proteases; Mitochondrial calcium ion transport"	"5"	"0"	"471.7"	"235.4"	"328.3"	"139.9"	"290.2"	"301.5"	"328.2"	"199.3"	"165.2"	"431.1"	"576.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9C0J8"	"pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2"	"4"	"3"	"5"	"3"	"1336"	"145.8"	"9.17"	"661.02"	"12.36"	"2"	"3"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	""	"Pf00400"	"55339"	"ENSG00000136709"	"WDR33"	"hsa:55339; Q05DP8; Q53FG9; Q587J1; Q69YF7; Q6NUQ0; Q9C0J8; Q9NUL1"	""	"Transport of Mature mRNA Derived from an Intronless Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"5"	"0"	"81.4"	"48.8"	"66.2"	"77.6"	"69.9"	"80.0"	"161.0"	"147.8"	"111.3"	"179.1"	"235.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14008"	"Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3"	"2"	"4"	"7"	"4"	"2032"	"225.4"	"7.80"	"1147.28"	"12.34"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02985, Pf12348"	"9793"	"ENSG00000175216"	"CKAP5"	"hsa:9793; Q05D70; Q0VAX7; Q0VAX8; Q14008; Q14668; Q2TA89; Q6NSH4"	"4p16.3 copy number variation"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Separation of Sister Chromatids; RHO GTPases Activate Formins; Resolution of Sister Chromatid Cohesion; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"14"	"0"	"26.9"	"14.8"	"32.1"	"20.4"	"22.9"	"28.9"	"94.4"	"97.7"	"60.9"	"106.4"	"149.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02809"	"Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 OS=Homo sapiens OX=9606 GN=PLOD1 PE=1 SV=2"	"6"	"4"	"7"	"4"	"727"	"83.5"	"6.95"	"1050.13"	"12.34"	"3"	"4"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf03171"	"5351"	"ENSG00000083444"	"PLOD1"	"B4DR87; hsa:5351; Q02809; Q96AV9; Q9H132"	"Type I collagen synthesis in the context of osteogenesis imperfecta"	"Collagen biosynthesis and modifying enzymes"	"2"	"0"	"178.9"	"106.8"	"177.7"	"178.3"	"196.2"	"198.8"	"413.8"	"402.2"	"312.4"	"436.4"	"521.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P41567"	"Eukaryotic translation initiation factor 1 OS=Homo sapiens OX=9606 GN=EIF1 PE=1 SV=1"	"33"	"2"	"5"	"1"	"113"	"12.7"	"7.44"	"818.25"	"12.33"	"1"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf01253"	"10209"	"ENSG00000173812"	"EIF1"	"hsa:10209; P41567; Q9UNQ9"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	""	"2"	"0"	"38.4"	"22.9"	"32.0"	"43.2"	"35.8"	"40.5"	"94.3"	"85.4"	"59.2"	"139.2"	"321.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4E8"	"Ubiquitin carboxyl-terminal hydrolase 15 OS=Homo sapiens OX=9606 GN=USP15 PE=1 SV=3"	"4"	"4"	"8"	"4"	"981"	"112.3"	"5.22"	"1237.37"	"12.30"	"4"	"4"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00443, Pf06337, Pf14533, Pf14836"	"9958"	"ENSG00000135655"	"USP15"	"hsa:9958; Q08AL5; Q9H8G9; Q9HCA6; Q9UNP0; Q9Y4E8; Q9Y5B5"	""	"Ub-specific processing proteases; UCH proteinases; Downregulation of TGF-beta receptor signaling"	"3"	"0"	"281.1"	"152.2"	"216.1"	"287.0"	"239.0"	"318.4"	"468.3"	"484.4"	"362.6"	"543.6"	"734.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18669"	"Phosphoglycerate mutase 1 OS=Homo sapiens OX=9606 GN=PGAM1 PE=1 SV=2"	"18"	"3"	"6"	"3"	"254"	"28.8"	"7.18"	"1120.57"	"12.29"	"3"	"3"	"other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;other cell component"	"other molecular function"	"Pf00300"	"5223"	"ENSG00000171314"	"PGAM1"	"hsa:5223; P18669; Q9BWC0"	"Cori cycle; Metabolic reprogramming in colon cancer; Warburg effect modulated by deubiquitinating enzymes and their substrates; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"Neutrophil degranulation; Glycolysis; Gluconeogenesis"	"8"	"0"	"172.8"	"135.5"	"218.8"	"106.2"	"149.7"	"177.9"	"204.8"	"149.7"	"125.4"	"253.9"	"341.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92665"	"28S ribosomal protein S31, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS31 PE=1 SV=3"	"15"	"5"	"7"	"5"	"395"	"45.3"	"9.29"	"609.83"	"12.23"	"2"	"5"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf15433"	"10240"	"ENSG00000102738"	"MRPS31"	"B2RCS3; hsa:10240; Q5VYC8; Q8WTV8; Q92665"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"140.1"	"84.9"	"117.5"	"121.0"	"111.8"	"151.1"	"285.7"	"285.2"	"272.6"	"430.3"	"666.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46063"	"ATP-dependent DNA helicase Q1 OS=Homo sapiens OX=9606 GN=RECQL PE=1 SV=3"	"9"	"5"	"7"	"5"	"649"	"73.4"	"7.88"	"1032.83"	"12.23"	"3"	"4"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf16124"	"5965"	"ENSG00000004700"	"RECQL"	"A8K6G2; hsa:5965; P46063"	"Progeria-associated lipodystrophy"	""	"1"	"0"	"117.5"	"76.2"	"106.2"	"77.2"	"102.6"	"106.9"	"361.4"	"330.2"	"265.5"	"308.8"	"415.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4Z0"	"U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1"	"26"	"4"	"10"	"4"	"139"	"15.3"	"9.99"	"2009.88"	"12.10"	"4"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01423"	"25804"	"ENSG00000130520"	"LSM4"	"hsa:25804; Q9Y4Z0"	"Ciliary landscape"	"mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease"	"3"	"0"	"493.8"	"317.5"	"474.0"	"371.3"	"398.6"	"435.5"	"938.4"	"862.9"	"638.9"	"1065.4"	"1370.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20290"	"Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1"	"33"	"4"	"6"	"4"	"206"	"22.2"	"9.38"	"985.75"	"12.10"	"2"	"3"	"transport;developmental processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	""	"Pf01849"	"689"	"ENSG00000145741"	"BTF3"	"A8K510; hsa:689; P20290; Q13893; Q76M56"	"Orexin receptor pathway"	""	"1"	"0"	"331.1"	"194.7"	"263.4"	"278.0"	"283.5"	"315.3"	"952.9"	"746.6"	"483.9"	"736.4"	"781.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15344"	"E3 ubiquitin-protein ligase Midline-1 OS=Homo sapiens OX=9606 GN=MID1 PE=1 SV=1"	"8"	"5"	"8"	"5"	"667"	"75.2"	"6.80"	"1237.76"	"12.10"	"4"	"4"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00041, Pf00622, Pf00643, Pf13445, Pf13765, Pf18568"	"4281"	"ENSG00000101871"	"MID1"	"B2RCG2; hsa:4281; O15344; O75361; Q9BZX5"	""	"Interferon gamma signaling"	"1"	"0"	"134.2"	"81.8"	"134.5"	"118.7"	"132.8"	"145.4"	"354.4"	"445.9"	"394.5"	"664.7"	"885.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14136"	"Glial fibrillary acidic protein OS=Homo sapiens OX=9606 GN=GFAP PE=1 SV=1"	"8"	"3"	"6"	"1"	"432"	"49.9"	"5.52"	"394.04"	"12.09"	"1"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00038, Pf04732"	"2670"	"ENSG00000131095"	"GFAP"	"A7REI1; B2RD44; D3DX59; E9PAX3; hsa:2670; P14136; Q53H98; Q5D055; Q6ZQS3; Q7Z5J6; Q7Z5J7; Q96KS4; Q96P18; Q9UFD0"	"Neural crest differentiation; Spinal cord injury; Neuroinflammation and glutamatergic signaling"	"Chaperone Mediated Autophagy; Nuclear signaling by ERBB4"	"5"	"0"	"52.1"	"58.2"	"40.5"	"92.5"	"43.7"	"49.0"	"64.6"	"68.6"	"68.1"	"95.5"	"158.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P15531"	"Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1"	"41"	"5"	"8"	"2"	"152"	"17.1"	"6.19"	"1347.62"	"12.00"	"4"	"4"	"DNA metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"translation activity;kinase activity;other molecular function"	"Pf00334"	"4830"	"ENSG00000239672"	"NME1"	"hsa:4830; P15531; Q6FGK3; Q86XQ2; Q9UDJ6"	"Pyrimidine metabolism"	"Interconversion of nucleotide di- and triphosphates; Azathioprine ADME; Ribavirin ADME"	"4"	"2"	"411.0"	"266.3"	"402.4"	"282.2"	"341.5"	"361.7"	"526.9"	"429.3"	"326.4"	"625.4"	"1010.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00492"	"Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=HPRT1 PE=1 SV=2"	"26"	"5"	"9"	"5"	"218"	"24.6"	"6.68"	"1809.36"	"11.96"	"5"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;developmental processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00156"	"3251"	"ENSG00000165704"	"HPRT1"	"A6NHF0; B2R8M9; hsa:3251; P00492"	"Mesodermal commitment pathway"	"Azathioprine ADME; Purine salvage; Defective HPRT1 disrupts guanine and hypoxanthine salvage"	"4"	"0"	"367.4"	"275.2"	"431.6"	"271.2"	"349.3"	"375.9"	"388.1"	"304.6"	"217.2"	"427.1"	"662.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35611"	"Alpha-adducin OS=Homo sapiens OX=9606 GN=ADD1 PE=1 SV=2"	"7"	"4"	"8"	"4"	"737"	"80.9"	"5.83"	"1493.93"	"11.96"	"4"	"4"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00596"	"118"	"ENSG00000087274"	"ADD1"	"A2A3N8; A2A3P0; B4DI79; D3DVR3; D3DVR4; D3DVR5; hsa:118; P35611; Q13734; Q14729; Q16156; Q86XM2; Q9UJB6"	""	"XBP1(S) activates chaperone genes; Caspase-mediated cleavage of cytoskeletal proteins; Miscellaneous transport and binding events"	"3"	"0"	"231.8"	"155.4"	"206.4"	"226.2"	"236.6"	"276.9"	"479.1"	"483.0"	"375.3"	"538.1"	"711.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15145"	"Actin-related protein 2/3 complex subunit 3 OS=Homo sapiens OX=9606 GN=ARPC3 PE=1 SV=3"	"21"	"4"	"7"	"4"	"178"	"20.5"	"8.59"	"1107.29"	"11.94"	"3"	"4"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf04062"	"10094"	"ENSG00000111229"	"ARPC3"	"hsa:10094; O00554; O15145"	"Pathogenic Escherichia coli infection"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"6"	"0"	"114.3"	"89.2"	"148.7"	"127.4"	"164.8"	"158.9"	"474.9"	"684.0"	"682.5"	"1286.7"	"3186.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62195"	"26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1"	"11"	"4"	"8"	"4"	"406"	"45.6"	"7.55"	"1619.74"	"11.93"	"4"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00004, Pf16450, Pf17862"	"5705"	"ENSG00000087191"	"PSMC5"	"A8K3Z3; A8K763; hsa:5705; O35051; O43208; P47210; P52915; P52916; P62195"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Pregnane X receptor pathway; Nuclear receptors meta-pathway; Alzheimer's disease"	"Regulation of expression of SLITs and ROBOs; UCH proteinases; Ub-specific processing proteases; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"65"	"0"	"195.2"	"120.8"	"171.9"	"136.0"	"166.2"	"191.2"	"279.5"	"251.0"	"188.3"	"269.6"	"365.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BV38"	"WD repeat-containing protein 18 OS=Homo sapiens OX=9606 GN=WDR18 PE=1 SV=2"	"11"	"4"	"8"	"4"	"432"	"47.4"	"6.70"	"1408.06"	"11.78"	"4"	"4"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf00400, Pf14077"	"57418"	"ENSG00000065268"	"WDR18"	"hsa:57418; O60390; Q9BV38; Q9BWR2"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"179.4"	"132.3"	"212.0"	"199.4"	"221.1"	"207.2"	"336.7"	"346.1"	"268.8"	"418.7"	"505.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46087"	"Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NOP2 PE=1 SV=2"	"5"	"4"	"8"	"4"	"812"	"89.2"	"9.23"	"1272.13"	"11.75"	"4"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf01189, Pf08062, Pf17125"	"4839"	"ENSG00000111641"	"NOP2"	"A1A4Z3; B3KPD6; hsa:4839; P46087; Q05BA7; Q0P5S5; Q3KQS4; Q58F30"	"Imatinib and chronic myeloid leukemia"	"rRNA modification in the nucleus and cytosol; TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"	"3"	"0"	"196.8"	"131.8"	"169.5"	"182.5"	"194.1"	"196.0"	"815.6"	"725.5"	"527.3"	"893.5"	"1333.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15530"	"3-phosphoinositide-dependent protein kinase 1 OS=Homo sapiens OX=9606 GN=PDPK1 PE=1 SV=1"	"6"	"2"	"6"	"2"	"556"	"63.1"	"7.36"	"1312.66"	"11.74"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf14593"	"5170"	"ENSG00000140992"	"PDPK1"	"H0Y4Z0; hsa:5170; O15530; Q59EH6; Q6FI20; Q8IV52; Q9BRD5"	"MicroRNAs in cardiomyocyte hypertrophy; Integrin-mediated cell adhesion; Thyroid stimulating hormone (TSH) signaling pathway; Glioblastoma signaling pathways; B cell receptor signaling pathway; Interleukin-11 signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Cardiac hypertrophic response; Focal adhesion; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Leptin-insulin signaling overlap; PPAR signaling pathway; Endometrial cancer; PI3K-Akt signaling pathway; EGF/EGFR signaling pathway; Head and neck squamous cell carcinoma; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; Modulators of TCR signaling and T cell activation; GDNF signaling; Primary ovarian insufficiency; A network map of Macrophage-stimulating protein (MSP) signaling; ErbB signaling pathway; T-cell receptor signaling pathway; Serotonin HTR1 group and FOS pathway"	"Role of LAT2/NTAL/LAB on calcium mobilization; FCERI mediated NF-kB activation; Downstream TCR signaling; CLEC7A (Dectin-1) signaling; Constitutive Signaling by AKT1 E17K in Cancer; PIP3 activates AKT signaling; Regulation of TP53 Degradation; GPVI-mediated activation cascade; CD28 dependent PI3K/Akt signaling; G beta:gamma signalling through PI3Kgamma; RHO GTPases activate PKNs; Activation of AKT2; Integrin signaling; RSK activation; VEGFR2 mediated vascular permeability; VEGFR2 mediated cell proliferation; Estrogen-stimulated signaling through PRKCZ; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways"	"46"	"0"	"3.9"	"4.2"	"19.9"	"6.6"	"3.6"	"16.2"	"27.2"	"17.5"	"13.9"	"29.5"	"48.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P41250"	"Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3"	"8"	"4"	"6"	"3"	"739"	"83.1"	"7.03"	"570.71"	"11.72"	"2"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"non-structural extracellular;cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00458, Pf00587, Pf03129"	"2617"	"ENSG00000106105"	"GARS1"	"A0A090N8G0; B3KQA2; B4DIA0; hsa:2617; P41250; Q969Y1"	""	"Cytosolic tRNA aminoacylation; Mitochondrial tRNA aminoacylation"	"2"	"0"	"61.0"	"38.1"	"61.5"	"55.1"	"54.5"	"64.2"	"109.2"	"88.7"	"73.1"	"119.3"	"181.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7RTV0"	"PHD finger-like domain-containing protein 5A OS=Homo sapiens OX=9606 GN=PHF5A PE=1 SV=1"	"34"	"4"	"7"	"4"	"110"	"12.4"	"8.41"	"897.44"	"11.70"	"3"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03660"	"84844"	"ENSG00000100410"	"PHF5A"	"hsa:84844; Q7RTV0; Q9UH06"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"770.7"	"498.5"	"628.5"	"579.4"	"574.2"	"659.7"	"1757.3"	"1467.2"	"987.1"	"1824.2"	"2455.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NW64"	"Pre-mRNA-splicing factor RBM22 OS=Homo sapiens OX=9606 GN=RBM22 PE=1 SV=1"	"10"	"4"	"8"	"4"	"420"	"46.9"	"8.54"	"1447.99"	"11.67"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"55696"	"ENSG00000086589"	"RBM22"	"A6NDM5; B4DLI9; hsa:55696; O95607; Q9NW64"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"353.8"	"204.9"	"250.7"	"248.4"	"288.6"	"335.3"	"708.7"	"670.4"	"488.6"	"726.4"	"885.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25098"	"Beta-adrenergic receptor kinase 1 OS=Homo sapiens OX=9606 GN=GRK2 PE=1 SV=2"	"6"	"4"	"7"	"4"	"689"	"79.5"	"7.28"	"954.27"	"11.66"	"3"	"4"	"cell-cell signaling;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf00069, Pf00169, Pf00615"	"156"	"ENSG00000173020"	"GRK2"	"B0ZBE1; hsa:156; P25098; Q13837; Q6GTT3"	"Chemokine signaling pathway; Hedgehog signaling pathway; Hedgehog signaling pathway"	"G alpha (q) signalling events; Activation of SMO; G alpha (s) signalling events; Cargo recognition for clathrin-mediated endocytosis; Calmodulin induced events"	"8"	"0"	"63.3"	"46.9"	"86.5"	"75.6"	"81.9"	"91.8"	"214.7"	"218.9"	"233.8"	"417.0"	"583.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15436"	"Protein transport protein Sec23A OS=Homo sapiens OX=9606 GN=SEC23A PE=1 SV=2"	"6"	"3"	"5"	"2"	"765"	"86.1"	"7.08"	"708.82"	"11.64"	"2"	"3"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00626, Pf04810, Pf04811, Pf04815, Pf08033"	"10484"	"ENSG00000100934"	"SEC23A"	"B2R5P4; B3KXI2; hsa:10484; Q15436; Q8NE16"	"Sterol regulatory element-binding proteins (SREBP) signaling"	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC; SARS-CoV-2 activates/modulates innate and adaptive immune responses; MHC class II antigen presentation; COPII-mediated vesicle transport; Cargo concentration in the ER; Regulation of cholesterol biosynthesis by SREBP (SREBF)"	"7"	"1"	"29.1"	"19.0"	"34.4"	"34.3"	"61.1"	"38.1"	"134.1"	"149.3"	"129.8"	"191.8"	"228.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z6Z7"	"E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3"	"1"	"2"	"3"	"2"	"4374"	"481.6"	"5.22"	""	"11.64"	""	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00627, Pf00632, Pf02825, Pf06012, Pf06025, Pf14377"	"10075"	"ENSG00000086758"	"HUWE1"	"hsa:10075; O15029; Q4G2Z2; Q5H961; Q6P4D0; Q7Z6Z7; Q8NG67; Q9BUI0; Q9HCJ4; Q9NSL6; Q9P0A9"	""	"Antigen processing: Ubiquitination & Proteasome degradation; Neutrophil degranulation"	"2"	"0"	"17.3"	"11.9"	"20.6"	"22.9"	"23.7"	"27.2"	"37.7"	"41.5"	"35.5"	"49.1"	"58.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61962"	"DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1"	"15"	"4"	"7"	"4"	"342"	"38.9"	"5.52"	"1076.16"	"11.62"	"3"	"4"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00400"	"10238"	"ENSG00000136485"	"DCAF7"	"B4E039; D3DU14; hsa:10238; O15491; P61962; Q9DAE4"	"Ciliary landscape; DYRK1A involvement regarding cell proliferation in brain development"	"Neddylation; Association of TriC/CCT with target proteins during biosynthesis"	"4"	"0"	"277.6"	"186.0"	"252.6"	"229.1"	"239.2"	"266.6"	"487.1"	"476.8"	"358.1"	"529.5"	"666.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P0CG39"	"POTE ankyrin domain family member J OS=Homo sapiens OX=9606 GN=POTEJ PE=3 SV=1"	"4"	"5"	"7"	"1"	"1038"	"117.3"	"5.97"	"946.30"	"11.60"	"3"	"4"	"cell organization and biogenesis;other biological processes"	"other membranes;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00022, Pf12796, Pf14915"	"653781"	"ENSG00000222038"	"POTEJ"	"hsa:653781; P0CG39"	""	""	"0"	"0"	"10.9"	"8.5"	"8.5"	"5.9"	"2.6"	"9.0"	"18.3"	"18.9"	"16.2"	"19.7"	"15.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01469"	"Fatty acid-binding protein 5 OS=Homo sapiens OX=9606 GN=FABP5 PE=1 SV=3"	"16"	"2"	"4"	"2"	"135"	"15.2"	"7.01"	"272.05"	"11.53"	"1"	"2"	"other metabolic processes;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00061"	"2171"	"ENSG00000164687"	"FABP5"	"B2R4K0; hsa:2171; Q01469"	"PPAR signaling pathway; Fatty acid transporters"	"Neutrophil degranulation; Triglyceride catabolism; Signaling by Retinoic Acid"	"5"	"0"	"85.2"	"58.7"	"152.4"	"44.7"	"74.0"	"75.2"	"169.8"	"168.0"	"139.5"	"203.7"	"918.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96FJ2"	"Dynein light chain 2, cytoplasmic OS=Homo sapiens OX=9606 GN=DYNLL2 PE=1 SV=1"	"21"	"3"	"8"	"2"	"89"	"10.3"	"7.37"	"1211.00"	"11.51"	"3"	"3"	"other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf01221"	"140735"	"ENSG00000264364"	"DYNLL2"	"B2R5B4; hsa:140735; Q96FJ2"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; 3q29 copy number variation syndrome"	"Separation of Sister Chromatids; Aggrephagy; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; MHC class II antigen presentation; HCMV Early Events; Intraflagellar transport; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Macroautophagy; Activation of BMF and translocation to mitochondria"	"18"	"1"	"892.7"	"484.9"	"713.7"	"602.8"	"744.2"	"785.3"	"953.0"	"934.2"	"734.7"	"1040.1"	"1505.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62633"	"Cellular nucleic acid-binding protein OS=Homo sapiens OX=9606 GN=CNBP PE=1 SV=1"	"24"	"3"	"4"	"3"	"177"	"19.5"	"7.71"	"420.21"	"11.50"	"1"	"3"	"DNA metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00098"	"7555"	"ENSG00000169714"	"CNBP"	"A8K7V4; B2RAV9; B4DP17; D3DNB9; D3DNC0; D3DNC1; E9PDR7; hsa:7555; P20694; P62633; Q4JGY0; Q4JGY1; Q5QJR0; Q5U0E9; Q6PJI7; Q96NV3"	""	"SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"1"	"0"	"97.6"	"78.7"	"102.0"	"111.0"	"139.8"	"125.8"	"189.4"	"190.0"	"139.4"	"249.2"	"319.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96CT7"	"Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1"	"15"	"4"	"8"	"4"	"223"	"25.8"	"9.54"	"1347.25"	"11.39"	"4"	"4"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf06244"	"115098"	"ENSG00000007080"	"CCDC124"	"hsa:115098; Q96CT7"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"383.4"	"221.7"	"305.7"	"298.9"	"327.1"	"322.1"	"1348.3"	"1289.1"	"912.8"	"1507.4"	"2386.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13283"	"Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1"	"11"	"4"	"7"	"3"	"466"	"52.1"	"5.52"	"1233.18"	"11.31"	"4"	"3"	"cell organization and biogenesis;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00076, Pf02136"	"10146"	"ENSG00000145907"	"G3BP1"	"hsa:10146; Q13283; Q5HYE9"	""	"SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"1"	"1"	"202.7"	"140.7"	"197.4"	"208.6"	"234.4"	"298.4"	"482.1"	"458.5"	"320.2"	"495.5"	"657.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15599"	"Na(+)/H(+) exchange regulatory cofactor NHE-RF2 OS=Homo sapiens OX=9606 GN=SLC9A3R2 PE=1 SV=2"	"8"	"2"	"4"	"2"	"337"	"37.4"	"7.93"	"1157.44"	"11.29"	"2"	"2"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00595, Pf09007"	"9351"	"ENSG00000065054"	"NHERF2"	"D3DU84; D3DU85; H3BSV6; hsa:9351; O00272; O00556; Q15599; Q3KQY7"	""	""	"0"	"0"	"34.8"	"25.7"	"38.1"	"40.2"	"36.4"	"43.3"	"88.2"	"96.4"	"92.4"	"241.8"	"562.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95777"	"U6 snRNA-associated Sm-like protein LSm8 OS=Homo sapiens OX=9606 GN=LSM8 PE=1 SV=3"	"38"	"3"	"6"	"3"	"96"	"10.4"	"4.48"	"1224.54"	"11.26"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	"51691"	"ENSG00000128534"	"LSM8"	"hsa:51691; O95777"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"231.8"	"172.6"	"265.5"	"192.9"	"194.6"	"256.1"	"421.5"	"355.7"	"281.0"	"444.3"	"715.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14744"	"Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4"	"6"	"4"	"7"	"4"	"637"	"72.6"	"6.29"	"854.82"	"11.12"	"3"	"4"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05185, Pf17285, Pf17286"	"10419"	"ENSG00000100462"	"PRMT5"	"A8MTP3; A8MZ91; B4DX49; B4DY30; B5BU10; D3DS33; E2QRE7; hsa:10419; O14744; Q6IBR1; Q9UKH1"	"Transcription co-factors SKI and SKIL protein partners; Nitric oxide metabolism in cystic fibrosis"	"snRNP Assembly; RMTs methylate histone arginines; Regulation of TP53 Activity through Methylation"	"5"	"0"	"559.2"	"358.6"	"555.9"	"493.5"	"548.9"	"566.0"	"912.1"	"865.6"	"686.4"	"1002.7"	"1312.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P6C2"	"RNA demethylase ALKBH5 OS=Homo sapiens OX=9606 GN=ALKBH5 PE=1 SV=2"	"12"	"2"	"3"	"2"	"394"	"44.2"	"9.09"	"439.28"	"11.11"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;ER/Golgi;nucleus"	"other molecular function"	"Pf13532"	"54890"	"ENSG00000091542"	"ALKBH5"	"B4DVJ4; D3DXC6; hsa:54890; Q6P6C2; Q9NXD6"	"Smith-Magenis and Potocki-Lupski syndrome copy number variation"	"Reversal of alkylation damage by DNA dioxygenases"	"2"	"0"	"27.6"	"19.1"	"23.3"	"24.8"	"34.5"	"31.1"	"94.4"	"83.8"	"60.5"	"106.1"	"129.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5RKV6"	"Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1"	"17"	"3"	"5"	"3"	"272"	"28.2"	"6.28"	"558.41"	"11.07"	"2"	"3"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	""	"Pf01138"	"118460"	"ENSG00000223496"	"EXOSC6"	"hsa:118460; Q5RKV6"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	"6"	"0"	"147.4"	"96.4"	"149.7"	"133.9"	"150.7"	"163.8"	"295.6"	"278.9"	"211.2"	"334.6"	"392.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30041"	"Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3"	"18"	"4"	"9"	"4"	"224"	"25.0"	"6.38"	"1652.52"	"11.06"	"4"	"3"	"other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00578, Pf10417"	"9588"	"ENSG00000117592"	"PRDX6"	"A8JZY7; hsa:9588; P30041; P32077; Q5TAH4; Q5ZEZ8"	"Nuclear receptors meta-pathway; NRF2 pathway; VEGFA-VEGFR2 signaling"	"Neutrophil degranulation; Detoxification of Reactive Oxygen Species"	"5"	"0"	"393.6"	"271.4"	"377.1"	"236.0"	"347.9"	"351.2"	"387.5"	"310.8"	"286.6"	"469.4"	"719.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22392"	"Nucleoside diphosphate kinase B OS=Homo sapiens OX=9606 GN=NME2 PE=1 SV=1"	"29"	"4"	"7"	"1"	"152"	"17.3"	"8.41"	"1489.32"	"11.05"	"4"	"3"	"cell adhesion;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00334"	"4831; 654364"	"ENSG00000243678"	"NME2"	"A8MWA3; hsa:4831; hsa:654364; P22392; Q1WM23; Q6LCT6"	"Pyrimidine metabolism"	"Neutrophil degranulation; Azathioprine ADME; Interconversion of nucleotide di- and triphosphates; Ribavirin ADME"	"5"	"0"	"110.7"	"73.5"	"110.3"	"65.2"	"99.0"	"90.2"	"224.3"	"168.9"	"122.9"	"270.7"	"405.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O76003"	"Glutaredoxin-3 OS=Homo sapiens OX=9606 GN=GLRX3 PE=1 SV=2"	"13"	"4"	"8"	"4"	"335"	"37.4"	"5.39"	"1276.20"	"11.05"	"4"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00085, Pf00462"	"10539"	"ENSG00000108010"	"GLRX3"	"B3KMP7; B3KMQ5; D3DRG2; hsa:10539; O76003; Q5JV01; Q96CE0; Q9P1B0; Q9P1B1"	""	"Iron uptake and transport"	"1"	"0"	"168.2"	"107.0"	"179.1"	"168.0"	"169.8"	"194.6"	"251.8"	"272.2"	"185.0"	"290.8"	"362.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14635"	"G2/mitotic-specific cyclin-B1 OS=Homo sapiens OX=9606 GN=CCNB1 PE=1 SV=1"	"4"	"2"	"6"	"2"	"433"	"48.3"	"7.47"	"1388.36"	"11.04"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00134, Pf02984"	"891"	"ENSG00000134057"	"CCNB1"	"A8K066; hsa:891; P14635; Q5TZP9"	"AMP-activated protein kinase signaling; miRNA regulation of DNA damage response; Cell cycle; Retinoblastoma gene in cancer; ATM signaling pathway; G1 to S cell cycle control; GDNF signaling; DNA damage response"	"The role of GTSE1 in G2/M progression after G2 checkpoint; Resolution of Sister Chromatid Cohesion; Nuclear Pore Complex (NPC) Disassembly; Regulation of PLK1 Activity at G2/M Transition; APC/C:Cdc20 mediated degradation of Cyclin B; Phosphorylation of the APC/C; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Cyclin A/B1/B2 associated events during G2/M transition; Transcriptional regulation by RUNX2; MASTL Facilitates Mitotic Progression; E2F-enabled inhibition of pre-replication complex formation; Golgi Cisternae Pericentriolar Stack Reorganization; Condensation of Prophase Chromosomes; Initiation of Nuclear Envelope (NE) Reformation; Polo-like kinase mediated events; Condensation of Prometaphase Chromosomes; Activation of NIMA Kinases NEK9, NEK6, NEK7; G2/M DNA replication checkpoint; Depolymerization of the Nuclear Lamina; Phosphorylation of Emi1"	"31"	"0"	"111.2"	"66.4"	"89.3"	"90.1"	"113.3"	"122.0"	"543.9"	"519.7"	"359.6"	"514.0"	"634.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99615"	"DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2"	"9"	"5"	"8"	"5"	"494"	"56.4"	"6.96"	"1284.70"	"10.99"	"4"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00226, Pf13181, Pf13414, Pf13432"	"7266"	"ENSG00000168259"	"DNAJC7"	"hsa:7266; Q7Z784; Q99615"	"Constitutive androstane receptor pathway; Pregnane X receptor pathway; Nuclear receptors meta-pathway"	"Regulation of HSF1-mediated heat shock response"	"4"	"0"	"200.0"	"126.3"	"204.2"	"284.5"	"243.4"	"384.4"	"884.4"	"908.5"	"619.0"	"672.4"	"744.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00231"	"26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3"	"13"	"4"	"7"	"4"	"422"	"47.4"	"6.48"	"1025.69"	"10.98"	"3"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf01399, Pf18055, Pf18503"	"5717"	"ENSG00000108671"	"PSMD11"	"A8K3I7; E1P663; hsa:5717; O00231; O00495; Q53FT5"	"Proteasome degradation; Parkin-ubiquitin proteasomal system pathway; VEGFA-VEGFR2 signaling"	"Separation of Sister Chromatids; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"63"	"0"	"172.8"	"131.5"	"166.2"	"148.4"	"155.0"	"173.6"	"268.2"	"257.6"	"209.3"	"354.0"	"445.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00629"	"Importin subunit alpha-3 OS=Homo sapiens OX=9606 GN=KPNA4 PE=1 SV=1"	"11"	"4"	"6"	"1"	"521"	"57.9"	"4.96"	"1112.24"	"10.92"	"3"	"3"	"cell-cell signaling;other metabolic processes;transport"	"other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf01749, Pf16186"	"3840"	"ENSG00000186432"	"KPNA4"	"A8K4S6; D3DNM2; hsa:3840; O00190; O00629"	"Leptin signaling pathway"	"ISG15 antiviral mechanism; NS1 Mediated Effects on Host Pathways"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99460"	"26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PSMD1 PE=1 SV=2"	"4"	"3"	"6"	"3"	"953"	"105.8"	"5.39"	"1384.58"	"10.86"	"3"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01851, Pf13646, Pf18004"	"5707"	"ENSG00000173692"	"PSMD1"	"B8ZZH9; hsa:5707; Q24JU0; Q53TI2; Q6GMU5; Q6P2P4; Q6PJM7; Q6PKG9; Q86VU1; Q8IV79; Q99460"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A; MAPK6/MAPK4 signaling; The role of GTSE1 in G2/M progression after G2 checkpoint; Neutrophil degranulation; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"64"	"0"	"89.1"	"58.9"	"84.6"	"99.8"	"82.5"	"100.6"	"174.5"	"157.4"	"125.7"	"201.5"	"214.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14654"	"Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1"	"5"	"5"	"7"	"5"	"1257"	"133.7"	"8.44"	"797.57"	"10.82"	"3"	"4"	"signal transduction"	"plasma membrane;other membranes;cytosol"	"signal transduction activity or receptor binding;other molecular function"	"Pf02174"	"8471"	"ENSG00000133124"	"IRS4"	"hsa:8471; O14654"	"Alzheimer's disease and miRNA effects; Adipogenesis; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Leptin-insulin signaling overlap; Insulin signaling; Alzheimer's disease"	"IRS-related events triggered by IGF1R"	"8"	"0"	"182.6"	"136.0"	"163.1"	"174.9"	"194.5"	"200.0"	"454.4"	"421.4"	"396.8"	"544.8"	"663.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49321"	"Nuclear autoantigenic sperm protein OS=Homo sapiens OX=9606 GN=NASP PE=1 SV=2"	"4"	"4"	"7"	"4"	"788"	"85.2"	"4.30"	"986.76"	"10.81"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf10516"	"4678"	"ENSG00000132780"	"NASP"	"A8K6H2; B4DQP3; D3DQ07; F5H3J2; hsa:4678; P49321; Q53GW5; Q5T622; Q5T625; Q96A69; Q9BTW2"	""	""	"0"	"0"	"638.7"	"403.7"	"512.4"	"443.2"	"479.6"	"576.8"	"898.1"	"806.6"	"608.4"	"967.4"	"1372.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09622"	"Dihydrolipoyl dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=DLD PE=1 SV=2"	"6"	"3"	"8"	"3"	"509"	"54.1"	"7.85"	"1313.55"	"10.81"	"3"	"3"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytoskeleton;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf02852, Pf07992"	"1738"	"ENSG00000091140"	"DLD"	"B2R5X0; B4DHG0; B4DT69; hsa:1738; P09622; Q14131; Q14167; Q59EV8; Q8WTS4"	"Fatty acid beta-oxidation; TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Tryptophan metabolism; 7q11.23 copy number variation syndrome; Neuroinflammation and glutamatergic signaling; Glycolysis and gluconeogenesis; 10q11.21q11.23 copy number variation syndrome; Metabolic Epileptic Disorders; TCA cycle (aka Krebs or citric acid cycle)"	"Lysine catabolism; Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid; Citric acid cycle (TCA cycle); Branched-chain amino acid catabolism; Glycine degradation"	"18"	"0"	"457.8"	"254.2"	"456.6"	"443.3"	"419.0"	"512.8"	"1154.1"	"1200.8"	"799.1"	"1269.0"	"1819.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95299"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFA10 PE=1 SV=1"	"10"	"3"	"6"	"3"	"355"	"40.7"	"8.48"	"1375.38"	"10.78"	"3"	"3"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion;other cell component"	"transporter activity"	"Pf01712"	"4705"	"ENSG00000130414"	"NDUFA10"	"hsa:4705; O95299; Q8WXC9"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; 2q37 copy number variation syndrome; Oxidative phosphorylation"	"Complex I biogenesis"	"6"	"0"	"128.4"	"93.5"	"119.0"	"119.8"	"130.7"	"132.9"	"275.6"	"261.8"	"186.7"	"292.3"	"307.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35244"	"Replication protein A 14 kDa subunit OS=Homo sapiens OX=9606 GN=RPA3 PE=1 SV=1"	"37"	"3"	"6"	"3"	"121"	"13.6"	"5.08"	"1190.35"	"10.78"	"3"	"3"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf08661"	"6119"	"ENSG00000106399"	"RPA3"	"hsa:6119; P35244; Q549U6"	"Retinoblastoma gene in cancer; G1 to S cell cycle control; DNA replication; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"HSF1 activation; Fanconi Anemia Pathway; Regulation of HSF1-mediated heat shock response; Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Meiotic recombination; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Removal of the Flap Intermediate; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"36"	"0"	"37.3"	"37.1"	"42.7"	"41.9"	"46.2"	"47.1"	"83.8"	"79.1"	"58.0"	"97.3"	"123.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNE7"	"E3 ubiquitin-protein ligase CHIP OS=Homo sapiens OX=9606 GN=STUB1 PE=1 SV=2"	"18"	"6"	"10"	"6"	"303"	"34.8"	"5.87"	"1963.48"	"10.77"	"6"	"4"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf04564, Pf12895, Pf18391"	"10273"	"ENSG00000103266"	"STUB1"	"A2IDB9; hsa:10273; O60526; Q969U2; Q9HBT1; Q9UNE7"	"Androgen receptor signaling pathway; Parkin-ubiquitin proteasomal system pathway"	"Antigen processing: Ubiquitination & Proteasome degradation; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Regulation of TNFR1 signaling; Regulation of necroptotic cell death; Downregulation of ERBB2 signaling; Downregulation of TGF-beta receptor signaling"	"10"	"0"	"221.4"	"127.4"	"192.1"	"200.4"	"183.5"	"235.6"	"748.6"	"724.5"	"533.3"	"663.6"	"700.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13555"	"Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens OX=9606 GN=CAMK2G PE=1 SV=4"	"8"	"3"	"6"	"1"	"558"	"62.6"	"7.83"	"1259.21"	"10.74"	"3"	"3"	"cell-cell signaling;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf08332"	"818"	"ENSG00000148660"	"CAMK2G"	"A0A0A0MS52; A0A0A0MT11; hsa:818; O00561; O15378; Q13279; Q13282; Q13555; Q13556; Q5SQZ3; Q5SQZ4; Q5SWX4; Q7KYX5; Q8N4I3; Q8NIA4"	"Energy metabolism; Myometrial relaxation and contraction pathways; NO/cGMP/PKG mediated neuroprotection; Splicing factor NOVA regulated synaptic proteins; Wnt signaling; Non-genomic actions of 1,25 dihydroxyvitamin D3; Disruption of postsynaptic signaling by CNV; Neuroinflammation and glutamatergic signaling; Calcium regulation in cardiac cells; ErbB signaling pathway"	"Assembly and cell surface presentation of NMDA receptors; Ion homeostasis; Ion transport by P-type ATPases; Signaling by BRAF and RAF1 fusions; Interferon gamma signaling; RAF activation; Ras activation upon Ca2+ influx through NMDA receptor; Regulation of MECP2 expression and activity; Unblocking of NMDA receptors, glutamate binding and activation; Negative regulation of NMDA receptor-mediated neuronal transmission; Long-term potentiation; Trafficking of AMPA receptors; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; Phase 0 - rapid depolarisation; HSF1-dependent transactivation; CaMK IV-mediated phosphorylation of CREB; CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde"	"31"	"0"	"11.4"	"9.5"	"9.6"	"12.2"	"14.9"	"8.8"	"16.1"	"19.4"	"13.7"	"21.3"	"27.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94842"	"TOX high mobility group box family member 4 OS=Homo sapiens OX=9606 GN=TOX4 PE=1 SV=1"	"6"	"3"	"6"	"3"	"621"	"66.2"	"5.06"	"1015.18"	"10.73"	"3"	"3"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00505"	"9878"	"ENSG00000092203"	"TOX4"	"B4DPY8; B4DSM0; E7EV69; hsa:9878; O94842"	""	""	"0"	"0"	"57.2"	"37.8"	"49.6"	"45.2"	"50.4"	"51.8"	"103.8"	"104.0"	"78.7"	"137.2"	"187.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15355"	"Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1"	"8"	"4"	"8"	"4"	"546"	"59.2"	"4.36"	"1229.83"	"10.72"	"4"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf00481"	"5496"	"ENSG00000115241"	"PPM1G"	"hsa:5496; O15355"	"VEGFA-VEGFR2 signaling; mRNA processing"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4Y9"	"U6 snRNA-associated Sm-like protein LSm5 OS=Homo sapiens OX=9606 GN=LSM5 PE=1 SV=3"	"25"	"1"	"2"	"1"	"91"	"9.9"	"4.54"	""	"10.70"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01423"	"23658"	"ENSG00000106355"	"LSM5"	"hsa:23658; Q9Y4Y9"	""	"mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease"	"2"	"0"	"27.1"	"15.5"	"30.2"	"22.9"	"27.6"	"31.2"	"45.4"	"42.5"	"31.2"	"65.9"	"74.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBU8"	"Mortality factor 4-like protein 1 OS=Homo sapiens OX=9606 GN=MORF4L1 PE=1 SV=2"	"10"	"3"	"6"	"3"	"362"	"41.4"	"9.28"	"1371.70"	"10.65"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf05712, Pf11717"	"10933"	"ENSG00000185787"	"MORF4L1"	"B4DKN6; B7Z6R1; D3DW88; hsa:10933; O95899; Q5QTS1; Q6NVX8; Q86YT7; Q9HBP6; Q9NSW5; Q9UBU8"	"Pathways affected in adenoid cystic carcinoma"	"HATs acetylate histones"	"2"	"0"	"74.9"	"39.1"	"60.2"	"61.5"	"71.7"	"72.9"	"425.5"	"387.3"	"328.7"	"512.4"	"519.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11233"	"Ras-related protein Ral-A OS=Homo sapiens OX=9606 GN=RALA PE=1 SV=1"	"11"	"2"	"6"	"2"	"206"	"23.6"	"7.11"	"1108.76"	"10.63"	"2"	"2"	"cell cycle OR cell proliferation;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00071"	"5898"	"ENSG00000006451"	"RALA"	"A4D1W3; hsa:5898; P11233"	"RalA downstream regulated genes; Chromosomal and microsatellite instability in colorectal cancer ; Ras signaling; Pancreatic adenocarcinoma pathway; EGF/EGFR signaling pathway"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; p38MAPK events"	"8"	"0"	"95.6"	"61.6"	"70.0"	"59.4"	"72.1"	"86.0"	"161.1"	"152.0"	"101.3"	"199.5"	"236.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13427"	"Peptidyl-prolyl cis-trans isomerase G OS=Homo sapiens OX=9606 GN=PPIG PE=1 SV=2"	"6"	"4"	"8"	"4"	"754"	"88.6"	"10.29"	"1147.32"	"10.62"	"4"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00160"	"9360"	"ENSG00000138398"	"PPIG"	"D3DPC5; D3DPC6; hsa:9360; O00706; Q13427; Q53R40; Q53SN4; Q96DG9"	""	"mRNA Splicing - Major Pathway; SARS-CoV-1 activates/modulates innate immune responses"	"2"	"0"	"226.9"	"162.2"	"193.7"	"156.0"	"205.2"	"228.6"	"583.1"	"478.9"	"363.9"	"647.1"	"845.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86UP2"	"Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1"	"5"	"6"	"9"	"6"	"1357"	"156.2"	"5.64"	"1923.35"	"10.62"	"6"	"3"	"transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi"	"cytoskeletal activity"	"Pf05104"	"3895"	"ENSG00000126777"	"KTN1"	"B4DZ88; hsa:3895; Q13999; Q14707; Q15387; Q17RZ5; Q5GGW3; Q86UP2; Q86W57"	"Glucocorticoid receptor pathway; Nuclear receptors meta-pathway"	"RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RND2 GTPase cycle; RHOG GTPase cycle; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; RND3 GTPase cycle; RHO GTPases activate KTN1"	"11"	"0"	"157.5"	"95.4"	"120.4"	"121.3"	"119.0"	"144.4"	"293.6"	"246.2"	"167.7"	"323.9"	"433.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43715"	"TP53-regulated inhibitor of apoptosis 1 OS=Homo sapiens OX=9606 GN=TRIAP1 PE=1 SV=1"	"39"	"3"	"6"	"3"	"76"	"8.8"	"5.48"	"1281.28"	"10.61"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf05254"	"51499"	"ENSG00000170855"	"TRIAP1"	"B2R4Z7; hsa:51499; O43715; Q5RKS5; Q6LCA7"	"5q35 copy number variation"	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"	"2"	"0"	"224.4"	"127.2"	"182.8"	"193.7"	"152.5"	"284.5"	"364.0"	"311.4"	"283.7"	"437.3"	"627.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBL3"	"Set1/Ash2 histone methyltransferase complex subunit ASH2 OS=Homo sapiens OX=9606 GN=ASH2L PE=1 SV=1"	"7"	"3"	"5"	"3"	"628"	"68.7"	"5.69"	"815.18"	"10.61"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00622"	"9070"	"ENSG00000129691"	"ASH2L"	"A8K7C3; D3DSW9; hsa:9070; O60659; O60660; Q96B62; Q9UBL3"	"Kleefstra syndrome"	"Deactivation of the beta-catenin transactivating complex; PKMTs methylate histone lysines; Formation of WDR5-containing histone-modifying complexes; Formation of the beta-catenin:TCF transactivating complex; Activation of anterior HOX genes in hindbrain development during early embryogenesis; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"	"7"	"0"	"42.5"	"37.7"	"47.7"	"63.4"	"42.8"	"52.4"	"141.4"	"129.2"	"77.8"	"146.6"	"172.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y277"	"Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1"	"17"	"4"	"6"	"3"	"283"	"30.6"	"8.66"	"743.55"	"10.60"	"2"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf01459"	"7419"	"ENSG00000078668"	"VDAC3"	"hsa:7419; Q9UIS0; Q9Y277"	"Alzheimer's disease and miRNA effects; Ferroptosis; Hepatitis B infection; Alzheimer's disease"	"Ub-specific processing proteases; Mitochondrial calcium ion transport"	"6"	"1"	"106.2"	"68.1"	"106.8"	"57.1"	"86.0"	"83.7"	"109.0"	"81.7"	"50.7"	"137.5"	"184.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63272"	"Transcription elongation factor SPT4 OS=Homo sapiens OX=9606 GN=SUPT4H1 PE=1 SV=1"	"31"	"2"	"5"	"2"	"117"	"13.2"	"8.06"	"728.55"	"10.60"	"1"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf06093"	"6827"	"ENSG00000213246"	"SUPT4H1"	"B2R4X8; D3DTZ4; hsa:6827; P63272; Q16550; Q62387; Q6ZP89"	"Initiation of transcription and translation elongation at the HIV-1 LTR"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes"	"16"	"0"	"94.4"	"70.5"	"85.5"	"104.2"	"86.7"	"96.4"	"190.6"	"193.7"	"141.1"	"191.6"	"195.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60568"	"Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 OS=Homo sapiens OX=9606 GN=PLOD3 PE=1 SV=1"	"6"	"3"	"5"	"3"	"738"	"84.7"	"6.05"	"922.74"	"10.56"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"non-structural extracellular;extracellular matrix;other membranes;ER/Golgi"	"other molecular function"	"Pf03171"	"8985"	"ENSG00000106397"	"PLOD3"	"B2R6W6; hsa:8985; O60568; Q540C3"	"VEGFA-VEGFR2 signaling; IL-18 signaling pathway"	"Collagen biosynthesis and modifying enzymes"	"3"	"0"	"103.9"	"80.0"	"107.9"	"98.9"	"101.7"	"106.5"	"188.7"	"171.5"	"134.3"	"213.9"	"294.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NR31"	"GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1"	"19"	"3"	"5"	"3"	"198"	"22.4"	"6.68"	"635.20"	"10.53"	"2"	"3"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00025"	"56681"	"ENSG00000079332"	"SAR1A"	"B4DQ19; hsa:56681; Q9NR31"	"Sterol regulatory element-binding proteins (SREBP) signaling"	""	"1"	"0"	"36.2"	"21.7"	"32.4"	"33.7"	"28.1"	"38.0"	"53.3"	"49.1"	"34.6"	"61.2"	"86.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20674"	"Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2"	"31"	"4"	"8"	"4"	"150"	"16.8"	"6.79"	"1322.64"	"10.52"	"4"	"4"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf02284"	"9377"	"ENSG00000178741"	"COX5A"	"hsa:9377; P20674; P30045; Q8TB65"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly; 5q35 copy number variation; Arachidonate epoxygenase / epoxide hydrolase"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"8"	"0"	"438.8"	"306.2"	"301.2"	"241.1"	"279.8"	"339.4"	"447.2"	"339.0"	"232.1"	"475.0"	"571.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P0C0S5"	"Histone H2A.Z OS=Homo sapiens OX=9606 GN=H2AZ1 PE=1 SV=2"	"20"	"2"	"7"	"1"	"128"	"13.5"	"10.58"	"1010.78"	"10.47"	"2"	"2"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125, Pf16211"	"3015"	"ENSG00000164032"	"H2AZ1"	"B2RD56; hsa:3015; P0C0S5; P17317; Q6I9U0"	"Proteasome degradation; Retinoblastoma gene in cancer; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma"	"Amyloid fiber formation"	"4"	"0"	"12.3"	"7.3"	"14.0"	"8.4"	"11.1"	"13.5"	"25.9"	"22.6"	"10.0"	"33.1"	"36.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60885"	"Bromodomain-containing protein 4 OS=Homo sapiens OX=9606 GN=BRD4 PE=1 SV=2"	"3"	"3"	"6"	"3"	"1362"	"152.1"	"9.19"	"1055.84"	"10.46"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00439, Pf17035, Pf17105"	"23476"	"ENSG00000141867"	"BRD4"	"hsa:23476; O60433; O60885; Q4G0X8; Q86YS8; Q96PD3"	"VEGFA-VEGFR2 signaling; 7q11.23 copy number variation syndrome"	"Potential therapeutics for SARS"	"3"	"0"	"71.4"	"50.5"	"64.3"	"71.6"	"83.5"	"75.7"	"231.3"	"238.0"	"154.2"	"204.7"	"290.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35914"	"Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Homo sapiens OX=9606 GN=HMGCL PE=1 SV=2"	"14"	"4"	"6"	"4"	"325"	"34.3"	"8.54"	"754.71"	"10.45"	"2"	"4"	"cell organization and biogenesis;other metabolic processes"	"cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00682"	"3155"	"ENSG00000117305"	"HMGCL"	"B4DUP4; B7UCC6; D3Y5K7; hsa:3155; P35914; Q6IBC0; Q96FP8"	"Amino acid metabolism"	"Peroxisomal protein import; Synthesis of Ketone Bodies"	"3"	"0"	"130.9"	"86.8"	"135.3"	"131.6"	"137.0"	"146.6"	"182.0"	"184.3"	"159.9"	"213.6"	"296.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P27694"	"Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2"	"9"	"6"	"10"	"6"	"616"	"68.1"	"7.21"	"1800.64"	"10.44"	"5"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01336, Pf04057, Pf08646, Pf16900"	"6117"	"ENSG00000132383"	"RPA1"	"A8K0Y9; hsa:6117; P27694; Q59ES9"	"Homologous recombination; Retinoblastoma gene in cancer; ATR signaling; G1 to S cell cycle control; DNA replication; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"SUMOylation of DNA damage response and repair proteins; Regulation of HSF1-mediated heat shock response; Fanconi Anemia Pathway; Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Meiotic recombination; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; HSF1 activation; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Removal of the Flap Intermediate; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"39"	"0"	"848.4"	"548.9"	"792.6"	"726.2"	"742.1"	"801.6"	"1228.5"	"1129.8"	"752.6"	"1259.9"	"1758.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6UXN9"	"WD repeat-containing protein 82 OS=Homo sapiens OX=9606 GN=WDR82 PE=1 SV=1"	"16"	"6"	"9"	"6"	"313"	"35.1"	"7.69"	"1413.65"	"10.41"	"5"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00400"	"80335"	"ENSG00000164091"	"WDR82"	"A8K5R5; hsa:80335; Q6UXN9; Q8TEB2"	""	"Formation of WDR5-containing histone-modifying complexes"	"1"	"0"	"686.5"	"480.8"	"590.4"	"454.8"	"638.6"	"591.5"	"880.7"	"862.4"	"692.5"	"1052.6"	"1523.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15514"	"DNA-directed RNA polymerase II subunit RPB4 OS=Homo sapiens OX=9606 GN=POLR2D PE=1 SV=1"	"23"	"2"	"3"	"2"	"142"	"16.3"	"4.79"	"454.96"	"10.39"	"1"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf03874"	"5433"	"ENSG00000144231"	"POLR2D"	"hsa:5433; O15514; Q52LT4"	"Pyrimidine metabolism"	"Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; mRNA Splicing - Major Pathway; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"42"	"0"	"140.2"	"86.2"	"135.4"	"134.8"	"117.0"	"130.6"	"305.6"	"281.4"	"173.0"	"300.1"	"352.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q32P28"	"Prolyl 3-hydroxylase 1 OS=Homo sapiens OX=9606 GN=P3H1 PE=1 SV=2"	"7"	"4"	"9"	"4"	"736"	"83.3"	"5.14"	"1618.77"	"10.38"	"4"	"3"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf13640"	"64175"	"ENSG00000117385"	"P3H1"	"hsa:64175; Q32P28; Q7KZR4; Q96BR8; Q96SK8; Q96SL5; Q96SN3; Q9H6K3; Q9HC86; Q9HC87"	"Type I collagen synthesis in the context of osteogenesis imperfecta"	"Collagen biosynthesis and modifying enzymes"	"2"	"0"	"297.6"	"181.9"	"282.1"	"245.1"	"248.3"	"293.9"	"385.7"	"407.1"	"317.6"	"476.5"	"646.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BTT0"	"Acidic leucine-rich nuclear phosphoprotein 32 family member E OS=Homo sapiens OX=9606 GN=ANP32E PE=1 SV=1"	"16"	"3"	"6"	"3"	"268"	"30.7"	"3.85"	"1191.74"	"10.38"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf14580"	"81611"	"ENSG00000143401"	"ANP32E"	"B4E0I6; E9PEA6; hsa:81611; Q5TB18; Q5TB20; Q8N1S4; Q8WWW9; Q9BTT0"	""	""	"0"	"0"	"121.4"	"82.4"	"112.1"	"88.2"	"116.7"	"121.6"	"226.3"	"199.1"	"130.1"	"258.4"	"317.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P37802"	"Transgelin-2 OS=Homo sapiens OX=9606 GN=TAGLN2 PE=1 SV=3"	"26"	"4"	"7"	"4"	"199"	"22.4"	"8.25"	"1590.66"	"10.32"	"4"	"3"	"cell organization and biogenesis;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton"	"cytoskeletal activity"	"Pf00307, Pf00402"	"8407"	"ENSG00000158710"	"TAGLN2"	"E9KL39; hsa:8407; P37802; Q5JRQ6; Q5JRQ7; Q6FGI1; Q9BUH5; Q9H4P0"	""	"Platelet degranulation"	"1"	"0"	"126.6"	"97.9"	"158.4"	"81.3"	"128.9"	"148.8"	"173.8"	"124.1"	"105.8"	"210.6"	"285.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WXH0"	"Nesprin-2 OS=Homo sapiens OX=9606 GN=SYNE2 PE=1 SV=3"	"1"	"4"	"7"	"3"	"6885"	"795.9"	"5.36"	"1065.09"	"10.30"	"3"	"4"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00435, Pf10541"	"23224"	"ENSG00000054654"	"SYNE2"	"B4DND7; B4DPR6; hsa:23224; I6XXQ5; Q540G1; Q86YP9; Q8N1S3; Q8NF49; Q8TER7; Q8WWW3; Q8WWW4; Q8WWW5; Q8WXH0; Q8WXH1; Q9NU50; Q9UFQ4; Q9Y2L4; Q9Y4R1"	"Ovarian infertility; Rett syndrome causing genes; Envelope proteins and their potential roles in EDMD physiopathology"	"Meiotic synapsis"	"4"	"0"	"90.9"	"67.1"	"72.3"	"80.2"	"91.5"	"105.8"	"187.0"	"182.0"	"120.1"	"199.9"	"290.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WXA9"	"Splicing regulatory glutamine/lysine-rich protein 1 OS=Homo sapiens OX=9606 GN=SREK1 PE=1 SV=1"	"7"	"2"	"3"	"2"	"508"	"59.3"	"10.39"	"332.89"	"10.28"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf00076"	"140890"	"ENSG00000153914"	"SREK1"	"A4FTW3; hsa:140890; Q2M1J0; Q86X37; Q8WXA9"	"mRNA processing"	""	"1"	"0"	"49.7"	"28.1"	"46.3"	"54.1"	"54.4"	"48.5"	"133.1"	"107.5"	"68.9"	"146.3"	"236.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62847"	"40S ribosomal protein S24 OS=Homo sapiens OX=9606 GN=RPS24 PE=1 SV=1"	"17"	"2"	"6"	"2"	"133"	"15.4"	"10.78"	"1333.44"	"10.27"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01282"	"6229"	"ENSG00000138326"	"RPS24"	"E7EPK6; hsa:6229; P16632; P62847; Q5T0P7; Q5T0P8; Q7Z3D1"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"187.5"	"145.9"	"217.8"	"163.3"	"191.7"	"184.7"	"348.0"	"295.1"	"209.3"	"371.9"	"600.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15511"	"Actin-related protein 2/3 complex subunit 5 OS=Homo sapiens OX=9606 GN=ARPC5 PE=1 SV=3"	"17"	"2"	"6"	"2"	"151"	"16.3"	"5.67"	"1163.52"	"10.25"	"2"	"2"	"cell organization and biogenesis;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf04699"	"10092"	"ENSG00000162704"	"ARPC5"	"A6NEC4; hsa:10092; O15511; Q6PG42"	"Pathogenic Escherichia coli infection; Regulation of actin cytoskeleton"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Neutrophil degranulation; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"8"	"0"	"135.5"	"93.0"	"123.0"	"122.4"	"132.2"	"156.0"	"251.2"	"322.6"	"302.2"	"533.0"	"1204.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62829"	"60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1"	"31"	"4"	"7"	"4"	"140"	"14.9"	"10.51"	"1402.73"	"10.21"	"4"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00238"	"9349"	"ENSG00000125691"	"RPL23"	"hsa:9349; P23131; P24048; P62829; Q29246; Q3SWV7; Q6P5S1"	"Cytoplasmic ribosomal proteins; 17q12 copy number variation syndrome"	"Regulation of expression of SLITs and ROBOs; SRP-dependent cotranslational protein targeting to membrane; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"552.7"	"347.7"	"484.5"	"419.5"	"477.3"	"470.1"	"1347.7"	"1160.8"	"792.0"	"1366.8"	"1847.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61254"	"60S ribosomal protein L26 OS=Homo sapiens OX=9606 GN=RPL26 PE=1 SV=1"	"27"	"5"	"10"	"5"	"145"	"17.2"	"10.55"	"1841.47"	"10.19"	"5"	"3"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00467, Pf16906"	"6154"	"ENSG00000161970"	"RPL26"	"B2R4F0; D3DTR8; hsa:6154; P61254; Q02877; Q6IPY2"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Peptide chain elongation; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"409.4"	"287.2"	"360.9"	"297.5"	"368.6"	"403.1"	"1340.9"	"1277.1"	"832.4"	"1435.6"	"1639.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15291"	"Retinoblastoma-binding protein 5 OS=Homo sapiens OX=9606 GN=RBBP5 PE=1 SV=2"	"8"	"3"	"5"	"3"	"538"	"59.1"	"5.10"	"561.51"	"10.18"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00400"	"5929"	"ENSG00000117222"	"RBBP5"	"A8K272; hsa:5929; Q15291; Q7Z6D8; Q8NDZ7"	"Kleefstra syndrome"	"Neddylation; Formation of WDR5-containing histone-modifying complexes; Formation of the beta-catenin:TCF transactivating complex; Deactivation of the beta-catenin transactivating complex; Activation of anterior HOX genes in hindbrain development during early embryogenesis; PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"	"8"	"0"	"92.8"	"59.8"	"98.4"	"70.7"	"84.6"	"80.0"	"184.2"	"155.2"	"127.6"	"186.2"	"273.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P80723"	"Brain acid soluble protein 1 OS=Homo sapiens OX=9606 GN=BASP1 PE=1 SV=2"	"32"	"5"	"10"	"5"	"227"	"22.7"	"4.63"	"3469.23"	"10.18"	"4"	"3"	"developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05466"	"10409"	"ENSG00000176788"	"BASP1"	"B4DJA8; D3DTD5; hsa:10409; O43596; P80723; Q5U0S0; Q9BWA5"	""	"RHOF GTPase cycle"	"1"	"0"	"529.3"	"302.9"	"557.5"	"296.8"	"510.0"	"340.5"	"621.7"	"545.9"	"416.4"	"626.5"	"1227.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15143"	"Actin-related protein 2/3 complex subunit 1B OS=Homo sapiens OX=9606 GN=ARPC1B PE=1 SV=3"	"8"	"2"	"5"	"1"	"372"	"40.9"	"8.35"	"621.70"	"10.14"	"1"	"2"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400"	"10095"	"ENSG00000130429"	"ARPC1B"	"hsa:10095; O15143; Q9BU00"	"Pathogenic Escherichia coli infection; Microglia pathogen phagocytosis pathway"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; EPHB-mediated forward signaling"	"6"	"0"	"32.2"	"22.1"	"43.3"	"32.9"	"40.3"	"44.3"	"109.5"	"133.0"	"102.3"	"208.0"	"401.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49327"	"Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3"	"2"	"4"	"7"	"4"	"2511"	"273.3"	"6.44"	"903.75"	"10.13"	"3"	"4"	"other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00107, Pf00109, Pf00550, Pf00698, Pf00975, Pf02801, Pf08242, Pf08659, Pf14765, Pf16197"	"2194"	"ENSG00000169710"	"FASN"	"hsa:2194; P49327; Q13479; Q16702; Q4LE83; Q6P4U5; Q6SS02; Q969R1; Q96C68; Q96IT0"	"AMP-activated protein kinase signaling; Sterol regulatory element-binding proteins (SREBP) signaling; SREBF and miR33 in cholesterol and lipid homeostasis; Liver X receptor pathway; Nuclear receptors meta-pathway; Fatty acid biosynthesis; Angiopoietin-like protein 8 regulatory pathway; Lipid metabolism pathway; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Omega-9 fatty acid synthesis; FOXA2 pathway"	"ChREBP activates metabolic gene expression; Activation of gene expression by SREBF (SREBP); Fatty acyl-CoA biosynthesis; NR1H2 & NR1H3 regulate gene expression linked to lipogenesis; Vitamin B5 (pantothenate) metabolism"	"18"	"0"	"73.4"	"44.4"	"81.5"	"50.1"	"68.3"	"64.5"	"97.3"	"82.7"	"72.4"	"111.7"	"130.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P16949"	"Stathmin OS=Homo sapiens OX=9606 GN=STMN1 PE=1 SV=3"	"28"	"4"	"7"	"4"	"149"	"17.3"	"5.97"	"1370.90"	"10.10"	"4"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00836"	"3925"	"ENSG00000117632"	"STMN1"	"A2A2D1; B2R4E7; B7Z8N4; D3DPJ5; hsa:3925; P16949"	"Microtubule cytoskeleton regulation; Retinoblastoma gene in cancer; RAC1/PAK1/p38/MMP2 pathway; MAPK signaling pathway; EGF/EGFR signaling pathway; IL-18 signaling pathway"	"Nuclear signaling by ERBB4"	"7"	"0"	"635.6"	"338.2"	"488.6"	"439.0"	"446.5"	"523.5"	"787.6"	"699.7"	"589.7"	"825.8"	"1205.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14444"	"Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2"	"3"	"2"	"6"	"2"	"709"	"78.3"	"5.25"	"896.98"	"10.05"	"2"	"2"	"cell organization and biogenesis;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf12287, Pf18293"	"4076"	"ENSG00000135387"	"CAPRIN1"	"A6NMY7; D3DR06; hsa:4076; Q14444; Q15074; Q6IMN4; Q6IMN7; Q9BV09"	""	""	"0"	"0"	"103.2"	"61.3"	"95.4"	"85.0"	"103.5"	"107.9"	"160.1"	"158.3"	"109.6"	"200.7"	"276.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96RF0"	"Sorting nexin-18 OS=Homo sapiens OX=9606 GN=SNX18 PE=1 SV=2"	"7"	"3"	"4"	"3"	"628"	"68.9"	"5.68"	"249.60"	"10.04"	"1"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00787, Pf10456, Pf14604"	"112574"	"ENSG00000178996"	"SNX18"	"B4E2B3; H7BXX3; hsa:112574; Q05BB3; Q0VG02; Q96RF0"	""	"Clathrin-mediated endocytosis"	"1"	"0"	"121.2"	"57.2"	"92.8"	"122.9"	"105.6"	"122.4"	"484.1"	"903.8"	"837.1"	"1600.2"	"2353.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43148"	"mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1"	"10"	"5"	"9"	"5"	"476"	"54.8"	"6.61"	"1513.37"	"9.99"	"5"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03291"	"8731"	"ENSG00000101654"	"RNMT"	"B0YJ90; D3DUJ5; hsa:8731; O43148; O94996; Q9UIJ9"	"mRNA processing; 15q25 copy number variation"	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE"	"5"	"0"	"243.2"	"126.6"	"160.9"	"229.6"	"181.3"	"238.2"	"423.8"	"398.1"	"260.3"	"398.4"	"587.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15294"	"UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3"	"3"	"3"	"5"	"3"	"1046"	"116.9"	"6.70"	"566.93"	"9.97"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00515, Pf13181, Pf13414, Pf13424, Pf13844"	"8473"	"ENSG00000147162"	"OGT"	"hsa:8473; O15294; Q7Z3K0; Q8WWM8; Q96CC1; Q9UG57"	"Ectoderm differentiation; Ectoderm differentiation; Pleural mesothelioma"	"UCH proteinases; Formation of WDR5-containing histone-modifying complexes; Regulation of necroptotic cell death; HATs acetylate histones"	"8"	"0"	"73.9"	"48.3"	"69.6"	"74.7"	"68.0"	"76.9"	"97.0"	"105.4"	"76.4"	"102.7"	"117.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O96000"	"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 OS=Homo sapiens OX=9606 GN=NDUFB10 PE=1 SV=3"	"20"	"3"	"6"	"3"	"172"	"20.8"	"8.48"	"998.51"	"9.87"	"3"	"3"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf10249"	"4716"	"ENSG00000140990"	"NDUFB10"	"hsa:4716; O96000; Q96II6"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Modulators of TCR signaling and T cell activation; Oxidative phosphorylation"	"Complex I biogenesis"	"6"	"0"	"126.7"	"105.7"	"125.1"	"96.5"	"117.6"	"134.3"	"223.4"	"216.3"	"148.7"	"252.8"	"308.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9GZS3"	"WD repeat-containing protein 61 OS=Homo sapiens OX=9606 GN=WDR61 PE=1 SV=1"	"15"	"3"	"6"	"3"	"305"	"33.6"	"5.47"	"996.22"	"9.86"	"3"	"3"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00400"	"80349"	"ENSG00000140395"	"SKIC8"	"D3DW84; hsa:80349; Q6IA22; Q7Z4X4; Q9GZS3"	""	"Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events; E3 ubiquitin ligases ubiquitinate target proteins; mRNA decay by 3' to 5' exoribonuclease"	"5"	"0"	"58.4"	"41.0"	"64.6"	"51.4"	"56.4"	"68.6"	"131.5"	"143.5"	"111.1"	"183.3"	"252.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P21796"	"Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2"	"17"	"4"	"6"	"3"	"283"	"30.8"	"8.54"	"1167.00"	"9.84"	"3"	"3"	"cell-cell signaling;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"transporter activity;other molecular function"	"Pf01459"	"7416"	"ENSG00000213585"	"VDAC1"	"B3KVK4; D3DQ93; hsa:7416; P21796; Q5FVE7; Q9UIQ5; Q9UPL0"	"Alzheimer's disease and miRNA effects; Alzheimer's disease; Arsenic metabolism and reactive oxygen species generation; Cholesterol metabolism; Fatty Acids and Lipoproteins Transport in Hepatocytes"	"Ub-specific processing proteases; Pyruvate metabolism; Mitochondrial protein import; PINK1-PRKN Mediated Mitophagy; Mitochondrial calcium ion transport"	"10"	"0"	"168.4"	"91.3"	"137.1"	"77.7"	"112.5"	"154.1"	"176.6"	"121.2"	"88.9"	"230.5"	"293.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P28070"	"Proteasome subunit beta type-4 OS=Homo sapiens OX=9606 GN=PSMB4 PE=1 SV=4"	"13"	"2"	"4"	"2"	"264"	"29.2"	"5.97"	"372.04"	"9.84"	"1"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00227"	"5692"	"ENSG00000159377"	"PSMB4"	"B2R9L3; hsa:5692; P28070; P31148; Q5SZS5; Q6IBI4; Q969L6"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Separation of Sister Chromatids; Ub-specific processing proteases; ABC-family proteins mediated transport; Defective CFTR causes cystic fibrosis; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; MAPK6/MAPK4 signaling; UCH proteinases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"62"	"0"	"55.4"	"33.3"	"51.8"	"52.7"	"53.0"	"51.3"	"113.9"	"96.9"	"76.8"	"131.7"	"161.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HCD5"	"Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2"	"7"	"3"	"6"	"3"	"579"	"65.5"	"9.60"	"1061.82"	"9.79"	"3"	"3"	"signal transduction;other biological processes"	"cytoskeleton;nucleus"	"other molecular function"	""	"57727"	"ENSG00000124160"	"NCOA5"	"B2RTV9; E1P5R0; hsa:57727; Q6HA99; Q9H1F2; Q9H2T2; Q9H4Y9; Q9HCD5"	""	""	"0"	"0"	"103.9"	"70.6"	"86.1"	"104.2"	"104.7"	"110.0"	"207.7"	"196.9"	"141.8"	"209.7"	"247.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43395"	"U4/U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2"	"6"	"4"	"7"	"4"	"683"	"77.5"	"9.50"	"1228.10"	"9.79"	"4"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf01480, Pf06544, Pf08572"	"9129"	"ENSG00000117360"	"PRPF3"	"B4DSY9; hsa:9129; O43395; O43446; Q5VT54"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"302.5"	"194.2"	"233.0"	"222.8"	"255.7"	"257.1"	"561.4"	"547.3"	"407.0"	"641.5"	"856.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UIL1"	"Short coiled-coil protein OS=Homo sapiens OX=9606 GN=SCOC PE=1 SV=2"	"11"	"1"	"4"	"1"	"159"	"18.0"	"8.85"	"1010.01"	"9.78"	"1"	"1"	"other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus"	""	"Pf10224"	"60592"	"ENSG00000153130"	"SCOC"	"B7WPH7; D3DNY7; E9PB65; hsa:60592; Q6P5T9; Q7L2Y0; Q7Z4P2; Q96JY9; Q9BZB2; Q9UIL1"	""	"Retrograde transport at the Trans-Golgi-Network"	"1"	"0"	"15.8"	"12.0"	"12.0"	"15.2"	"18.4"	"11.8"	"27.7"	"26.2"	"23.7"	"33.4"	"40.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75822"	"Eukaryotic translation initiation factor 3 subunit J OS=Homo sapiens OX=9606 GN=EIF3J PE=1 SV=2"	"15"	"4"	"7"	"4"	"258"	"29.0"	"4.83"	"1288.02"	"9.75"	"4"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf08597"	"8669"	"ENSG00000104131"	"EIF3J"	"B4DUI3; F5H425; hsa:8669; O75822; Q9BUD2; Q9H8Q2; Q9UI65"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"8"	"0"	"398.7"	"274.6"	"412.2"	"363.6"	"379.8"	"414.6"	"1040.0"	"978.2"	"661.1"	"1052.6"	"1573.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46778"	"60S ribosomal protein L21 OS=Homo sapiens OX=9606 GN=RPL21 PE=1 SV=2"	"21"	"3"	"7"	"3"	"160"	"18.6"	"10.49"	"1336.11"	"9.73"	"3"	"2"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;other cell component"	"other molecular function"	"Pf01157"	"6144"	"ENSG00000122026"	"RPL21"	"hsa:6144; P46778; Q16699"	"Cytoplasmic ribosomal proteins"	"SRP-dependent cotranslational protein targeting to membrane; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"471.5"	"281.5"	"393.4"	"286.0"	"390.3"	"370.1"	"1624.3"	"1396.7"	"945.6"	"1554.1"	"1917.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q52LJ0"	"Protein FAM98B OS=Homo sapiens OX=9606 GN=FAM98B PE=1 SV=2"	"9"	"3"	"8"	"3"	"433"	"45.5"	"8.69"	"1101.66"	"9.72"	"3"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf10239"	"283742"	"ENSG00000171262"	"FAM98B"	"A8MUW5; hsa:283742; Q52LJ0; Q8N935"	""	"tRNA processing in the nucleus"	"1"	"0"	"203.9"	"131.1"	"192.8"	"161.7"	"204.5"	"196.0"	"523.4"	"412.6"	"250.4"	"523.3"	"772.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P17980"	"26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3"	"10"	"4"	"7"	"4"	"439"	"49.2"	"5.24"	"1360.65"	"9.70"	"4"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf16450, Pf17862"	"5702"	"ENSG00000165916"	"PSMC3"	"B2R8V1; hsa:5702; P17980; Q3B757; Q3B865; Q53HU5; Q6GPG8; Q6IBS1; Q96HD3"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"Neutrophil degranulation; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Separation of Sister Chromatids; ABC-family proteins mediated transport; Defective CFTR causes cystic fibrosis; UCH proteinases; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; The role of GTSE1 in G2/M progression after G2 checkpoint; Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; MAPK6/MAPK4 signaling; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"64"	"0"	"171.0"	"110.7"	"157.4"	"156.0"	"151.4"	"154.4"	"267.7"	"290.9"	"208.8"	"344.7"	"428.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P43034"	"Platelet-activating factor acetylhydrolase IB subunit alpha OS=Homo sapiens OX=9606 GN=PAFAH1B1 PE=1 SV=2"	"9"	"3"	"5"	"2"	"410"	"46.6"	"7.37"	"528.07"	"9.69"	"2"	"3"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf08513"	"5048"	"ENSG00000007168"	"PAFAH1B1"	"B2R7Q7; hsa:5048; P43034; Q8WZ88; Q8WZ89"	"Wnt signaling pathway and pluripotency; Ciliary landscape; Neurogenesis regulation in the olfactory epithelium; PAFAH1B1 copy number variation"	"Resolution of Sister Chromatid Cohesion; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Separation of Sister Chromatids; RHO GTPases Activate Formins; COPI-independent Golgi-to-ER retrograde traffic; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"18"	"0"	"126.3"	"72.6"	"116.4"	"107.8"	"104.6"	"109.7"	"340.5"	"317.2"	"234.4"	"337.3"	"513.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30086"	"Phosphatidylethanolamine-binding protein 1 OS=Homo sapiens OX=9606 GN=PEBP1 PE=1 SV=3"	"19"	"3"	"5"	"3"	"187"	"21.0"	"7.53"	"1294.67"	"9.67"	"3"	"2"	"other biological processes"	"cytosol"	"enzyme regulator activity;other molecular function"	"Pf01161"	"5037"	"ENSG00000089220"	"PEBP1"	"B2R4S1; hsa:5037; P30086"	"Pancreatic adenocarcinoma pathway; EGF/EGFR signaling pathway"	"Signaling by BRAF and RAF1 fusions; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; MAP2K and MAPK activation; Negative regulation of MAPK pathway; Signaling by high-kinase activity BRAF mutants"	"9"	"0"	"422.3"	"297.9"	"405.0"	"291.8"	"381.7"	"401.6"	"485.1"	"368.7"	"256.9"	"509.6"	"769.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IX01"	"SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2"	"7"	"4"	"5"	"4"	"1082"	"120.1"	"7.28"	"658.19"	"9.67"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf01585, Pf01805"	"10147"	"ENSG00000064607"	"SUGP2"	"C9JI71; hsa:10147; O15071; O60369; Q5JPH7; Q8IX01; Q8WUF7"	"mRNA processing"	""	"1"	"0"	"144.9"	"91.0"	"112.6"	"101.8"	"124.1"	"130.9"	"211.8"	"186.1"	"130.4"	"237.0"	"312.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P2E9"	"Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5"	"5"	"6"	"9"	"5"	"1410"	"152.4"	"8.60"	"1551.22"	"9.62"	"5"	"4"	"protein metabolism;other metabolic processes;transport"	"other membranes;ER/Golgi;translational apparatus"	"other molecular function"	"Pf05104"	"6238"	"ENSG00000125844"	"RRBP1"	"A0A0A0MRV0; A2A2S6; A6NCN6; hsa:6238; O75300; O75301; Q5W165; Q96SB2; Q9BWP1; Q9H476; Q9P2E9"	"Ectoderm differentiation"	"Signaling by ALK fusions and activated point mutants"	"2"	"1"	"265.5"	"149.9"	"234.5"	"211.9"	"255.6"	"231.7"	"714.1"	"598.9"	"500.5"	"756.3"	"1040.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96FV9"	"THO complex subunit 1 OS=Homo sapiens OX=9606 GN=THOC1 PE=1 SV=1"	"5"	"3"	"5"	"3"	"657"	"75.6"	"4.98"	"613.51"	"9.61"	"2"	"3"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;transport;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00531, Pf11957"	"9984"	"ENSG00000079134"	"THOC1"	"B2RBP6; hsa:9984; Q15219; Q64I72; Q64I73; Q96FV9"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"3"	"0"	"128.5"	"106.9"	"133.9"	"136.7"	"128.4"	"168.3"	"298.7"	"306.8"	"232.6"	"361.8"	"419.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04843"	"Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1"	"5"	"3"	"6"	"3"	"607"	"68.5"	"6.38"	"918.80"	"9.57"	"3"	"3"	"protein metabolism;other metabolic processes"	"other membranes;cytosol;ER/Golgi;other cell component"	""	"Pf04597"	"6184"	"ENSG00000163902"	"RPN1"	"B2R5Z0; D3DNB6; hsa:6184; P04843; Q68DT1"	"Proteasome degradation; N-glycan biosynthesis"	"SRP-dependent cotranslational protein targeting to membrane; Asparagine N-linked glycosylation; Maturation of spike protein"	"5"	"0"	"216.4"	"125.7"	"204.3"	"138.4"	"195.9"	"185.1"	"333.3"	"308.4"	"217.2"	"434.4"	"537.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P29401"	"Transketolase OS=Homo sapiens OX=9606 GN=TKT PE=1 SV=3"	"7"	"3"	"5"	"3"	"623"	"67.8"	"7.66"	"828.45"	"9.52"	"2"	"3"	"other metabolic processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf00456, Pf02779, Pf02780"	"7086"	"ENSG00000163931"	"TKT"	"A8K089; B4DE31; E7EPA7; hsa:7086; P29401; Q8TBA3; Q96HH3"	"Pentose phosphate metabolism; VEGFA-VEGFR2 signaling; Metabolic reprogramming in colon cancer; Thiamine metabolic pathways"	"NFE2L2 regulates pentose phosphate pathway genes; Pentose phosphate pathway; Insulin effects increased synthesis of Xylulose-5-Phosphate"	"7"	"0"	"109.4"	"52.7"	"98.0"	"97.6"	"115.3"	"94.1"	"278.2"	"235.7"	"165.9"	"320.3"	"471.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q05048"	"Cleavage stimulation factor subunit 1 OS=Homo sapiens OX=9606 GN=CSTF1 PE=1 SV=1"	"9"	"5"	"9"	"5"	"431"	"48.3"	"6.58"	"1333.56"	"9.52"	"5"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf00400, Pf16699"	"1477"	"ENSG00000101138"	"CSTF1"	"hsa:1477; Q05048; Q5QPD8"	"mRNA processing"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"5"	"0"	"898.6"	"462.8"	"648.6"	"778.4"	"687.8"	"856.1"	"1485.7"	"1513.0"	"1139.7"	"1552.7"	"1951.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43242"	"26S proteasome non-ATPase regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PSMD3 PE=1 SV=2"	"8"	"3"	"5"	"3"	"534"	"60.9"	"8.44"	"554.77"	"9.51"	"2"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf01399, Pf08375"	"5709"	"ENSG00000108344"	"PSMD3"	"B3KMW9; B4DT72; hsa:5709; O43242; Q96EI2; Q9BQA4"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"64"	"0"	"132.7"	"81.6"	"112.6"	"115.6"	"117.9"	"113.7"	"217.9"	"197.1"	"161.3"	"236.1"	"343.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62244"	"40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2"	"31"	"5"	"11"	"5"	"130"	"14.8"	"10.13"	"2104.22"	"9.50"	"5"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00410"	"6210"	"ENSG00000134419"	"RPS15A"	"hsa:6210; P39027; P39031; P62244; Q3MHD9; Q8C023; Q9BV24"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"985.7"	"682.8"	"991.2"	"823.1"	"840.1"	"932.3"	"1797.3"	"1653.6"	"1202.1"	"1924.1"	"2676.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35240"	"Merlin OS=Homo sapiens OX=9606 GN=NF2 PE=1 SV=1"	"4"	"2"	"5"	"2"	"595"	"69.6"	"6.47"	"789.82"	"9.49"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity"	"Pf00373, Pf00769, Pf09379, Pf09380, Pf20492"	"4771"	"ENSG00000186575"	"NF2"	"hsa:4771; O95683; P35240; Q8WUJ2; Q969N0; Q969Q3; Q96T30; Q96T31; Q96T32; Q96T33; Q9BTW3; Q9UNG9; Q9UNH3; Q9UNH4"	"Ectoderm differentiation; Ectoderm differentiation; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-YAP signaling; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; 3q29 copy number variation syndrome; Pleural mesothelioma"	"Regulation of actin dynamics for phagocytic cup formation; RHO GTPases activate PAKs"	"10"	"0"	"62.7"	"23.5"	"41.4"	"43.8"	"43.0"	"52.8"	"225.6"	"226.7"	"164.8"	"295.6"	"540.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13148"	"TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1"	"7"	"3"	"6"	"3"	"414"	"44.7"	"6.19"	"961.92"	"9.45"	"3"	"3"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf18694"	"23435"	"ENSG00000120948"	"TARDBP"	"A4GUK4; A4GUK5; A4GUK6; B2R629; B4DJ45; E2PU12; hsa:23435; Q13148; Q53H27; Q6FI92; Q96DJ0"	"MECP2 and associated Rett syndrome"	""	"1"	"0"	"568.9"	"267.1"	"456.6"	"364.2"	"454.7"	"468.3"	"633.8"	"492.9"	"292.1"	"645.2"	"1030.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P41223"	"Protein BUD31 homolog OS=Homo sapiens OX=9606 GN=BUD31 PE=1 SV=2"	"33"	"6"	"8"	"6"	"144"	"17.0"	"8.82"	"1993.44"	"9.42"	"5"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf01125"	"8896"	"ENSG00000106245"	"BUD31"	"A4D274; B7Z4S9; D6W5S6; hsa:8896; P41223; Q6IB53; Q9UDV1"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"93.6"	"57.6"	"77.5"	"89.2"	"91.9"	"94.5"	"303.6"	"311.1"	"237.4"	"403.9"	"456.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99496"	"E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1"	"10"	"3"	"6"	"2"	"336"	"37.6"	"6.84"	"1127.42"	"9.41"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf13923, Pf16207"	"6045"	"ENSG00000121481"	"RNF2"	"B2RBS7; B3KRH1; hsa:6045; Q5TEN1; Q5TEN2; Q99496"	"FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; Pleural mesothelioma"	"Oxidative Stress Induced Senescence; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6; SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"	"11"	"1"	"193.3"	"105.6"	"161.9"	"160.2"	"167.6"	"202.3"	"282.5"	"296.6"	"225.4"	"318.7"	"380.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15212"	"Prefoldin subunit 6 OS=Homo sapiens OX=9606 GN=PFDN6 PE=1 SV=1"	"25"	"3"	"6"	"3"	"129"	"14.6"	"8.88"	"912.58"	"9.41"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"other cell component"	"other molecular function"	"Pf01920"	"10471"	"ENSG00000204220; ENSG00000206283; ENSG00000224782; ENSG00000235692; ENSG00000237335"	"PFDN6"	"hsa:10471; O15212"	"Cellular proteostasis"	"Prefoldin mediated transfer of substrate  to CCT/TriC"	"2"	"0"	"96.2"	"61.0"	"94.7"	"78.4"	"77.6"	"76.3"	"166.4"	"171.5"	"166.2"	"283.0"	"397.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14168"	"MAGUK p55 subfamily member 2 OS=Homo sapiens OX=9606 GN=MPP2 PE=1 SV=3"	"7"	"3"	"6"	"2"	"576"	"64.5"	"6.77"	"1134.36"	"9.41"	"3"	"3"	"cell-cell signaling;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	""	"Pf00595, Pf00625, Pf02828, Pf07653"	"4355"	"ENSG00000108852"	"MPP2"	"B4DGE9; B4DRJ0; B7Z3G8; E7EV80; E7EV91; E7EX01; hsa:4355; Q14168; Q53ES9; Q5CZB9; Q9BQJ2"	""	""	"0"	"0"	"33.2"	"32.7"	"33.7"	"47.8"	"31.1"	"41.6"	"81.6"	"78.1"	"60.3"	"91.3"	"122.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NFW8"	"N-acylneuraminate cytidylyltransferase OS=Homo sapiens OX=9606 GN=CMAS PE=1 SV=2"	"10"	"3"	"6"	"3"	"434"	"48.3"	"7.93"	"1177.76"	"9.35"	"3"	"3"	"other metabolic processes"	"nucleus"	"other molecular function"	"Pf02348"	"55907"	"ENSG00000111726"	"CMAS"	"hsa:55907; Q8NFW8; Q96AX5; Q9NQZ0"	""	"Sialic acid metabolism"	"1"	"0"	"32.8"	"22.7"	"38.7"	"34.8"	"42.3"	"36.1"	"93.6"	"96.3"	"78.2"	"122.4"	"120.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NFY9"	"Kelch repeat and BTB domain-containing protein 8 OS=Homo sapiens OX=9606 GN=KBTBD8 PE=1 SV=2"	"7"	"4"	"6"	"4"	"601"	"68.8"	"6.29"	"979.54"	"9.34"	"3"	"3"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	""	"Pf00651, Pf01344, Pf07707"	"84541"	"ENSG00000163376"	"KBTBD8"	"B4DTW6; hsa:84541; Q8NFY9; Q96JI5"	""	"Antigen processing: Ubiquitination & Proteasome degradation; Neddylation"	"2"	"0"	"17.4"	"11.3"	"18.0"	"19.5"	"17.4"	"21.7"	"45.0"	"71.7"	"87.7"	"148.3"	"156.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NX63"	"MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1"	"12"	"3"	"6"	"3"	"227"	"26.1"	"8.28"	"1075.21"	"9.34"	"3"	"3"	"cell organization and biogenesis"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf05300"	"54927"	"ENSG00000106554"	"CHCHD3"	"hsa:54927; Q9NX63"	""	"Cristae formation; Mitochondrial protein import"	"2"	"0"	"374.9"	"237.9"	"336.9"	"197.8"	"298.1"	"329.7"	"479.8"	"321.8"	"218.9"	"560.0"	"745.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6WKZ4"	"Rab11 family-interacting protein 1 OS=Homo sapiens OX=9606 GN=RAB11FIP1 PE=1 SV=3"	"4"	"4"	"8"	"4"	"1283"	"137.1"	"5.43"	"1668.42"	"9.32"	"4"	"3"	"transport;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00168, Pf09457"	"80223"	"ENSG00000156675"	"RAB11FIP1"	"hsa:80223; J3KNP0; Q307T1; Q6AZK4; Q6WKZ2; Q6WKZ4; Q6WKZ6; Q86YV4; Q8TDL1; Q9H642"	""	""	"0"	"0"	"151.2"	"75.8"	"115.2"	"118.3"	"120.6"	"132.8"	"298.9"	"501.7"	"574.0"	"888.8"	"976.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T8P6"	"RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3"	"3"	"3"	"6"	"2"	"1007"	"113.5"	"9.16"	"1221.14"	"9.29"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf01480"	"64062"	"ENSG00000139746"	"RBM26"	"B4DZE0; hsa:64062; Q2NKM2; Q2NKQ2; Q5CZH8; Q5T8P5; Q5T8P6; Q5T8P8; Q5U5P5; Q5W0G7; Q8N3H5; Q96K92; Q96SZ3; Q9H2F8; Q9H7F9; Q9P1G7"	""	""	"0"	"1"	"124.5"	"75.3"	"97.7"	"106.2"	"107.4"	"125.1"	"265.7"	"262.0"	"183.6"	"240.8"	"306.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BVP2"	"Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2"	"10"	"4"	"5"	"4"	"549"	"62.0"	"9.16"	"926.34"	"9.29"	"3"	"2"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01926, Pf08701"	"26354"	"ENSG00000163938"	"GNL3"	"B2RDC1; hsa:26354; Q5PU80; Q96SV6; Q96SV7; Q9BVP2; Q9UJY0"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"167.6"	"118.1"	"149.9"	"139.8"	"148.5"	"161.6"	"376.2"	"361.1"	"215.7"	"389.9"	"476.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92820"	"Gamma-glutamyl hydrolase OS=Homo sapiens OX=9606 GN=GGH PE=1 SV=2"	"14"	"4"	"6"	"4"	"318"	"35.9"	"7.11"	"1182.99"	"9.26"	"3"	"3"	"other metabolic processes"	"non-structural extracellular;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf07722"	"8836"	"ENSG00000137563"	"GGH"	"hsa:8836; Q92820"	"Fluoropyrimidine activity"	"Neutrophil degranulation"	"2"	"0"	"84.5"	"61.7"	"101.4"	"83.2"	"95.7"	"101.5"	"260.8"	"428.8"	"450.0"	"774.2"	"1353.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IZP0"	"Abl interactor 1 OS=Homo sapiens OX=9606 GN=ABI1 PE=1 SV=4"	"10"	"3"	"6"	"3"	"508"	"55.0"	"7.06"	"1924.53"	"9.19"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00018, Pf07815"	"10006"	"ENSG00000136754"	"ABI1"	"A9Z1Y6; B3KX62; B4DQ58; H7BXI6; hsa:10006; O15147; O76049; O95060; Q5T2R3; Q5T2R4; Q5T2R6; Q5T2R7; Q5T2R9; Q5W070; Q5W072; Q8IZP0; Q8TB63; Q96S81; Q9NXZ9; Q9NYB8"	"EGF/EGFR signaling pathway"	"Regulation of actin dynamics for phagocytic cup formation; VEGFA-VEGFR2 Pathway; FCGR3A-mediated phagocytosis; RAC1 GTPase cycle; RHO GTPases Activate WASPs and WAVEs; RAC2 GTPase cycle; RAC3 GTPase cycle"	"8"	"0"	"121.9"	"102.1"	"144.7"	"147.4"	"149.1"	"138.3"	"273.8"	"268.0"	"229.0"	"308.0"	"368.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61289"	"Proteasome activator complex subunit 3 OS=Homo sapiens OX=9606 GN=PSME3 PE=1 SV=1"	"16"	"4"	"7"	"4"	"254"	"29.5"	"5.95"	"1540.96"	"9.19"	"4"	"3"	"cell cycle OR cell proliferation;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02251, Pf02252"	"10197"	"ENSG00000131467"	"PSME3"	"A8K9A3; hsa:10197; O35563; P61289; P97373; Q12920; Q13172; Q9BQD9"	"Proteasome degradation"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"60"	"0"	"317.7"	"117.3"	"185.6"	"238.5"	"205.3"	"282.2"	"345.6"	"423.7"	"376.9"	"658.7"	"1182.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35269"	"General transcription factor IIF subunit 1 OS=Homo sapiens OX=9606 GN=GTF2F1 PE=1 SV=2"	"7"	"4"	"7"	"4"	"517"	"58.2"	"7.49"	"1474.73"	"9.18"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf05793"	"2962"	"ENSG00000125651"	"GTF2F1"	"B2RCS0; hsa:2962; P35269; Q9BWN0"	""	"Viral Messenger RNA Synthesis; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; mRNA Splicing - Major Pathway; Estrogen-dependent gene expression; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM"	"32"	"0"	"47.4"	"25.5"	"39.1"	"45.6"	"41.9"	"35.5"	"117.6"	"115.6"	"107.7"	"222.0"	"242.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86TS9"	"39S ribosomal protein L52, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL52 PE=1 SV=2"	"15"	"2"	"4"	"2"	"123"	"13.7"	"10.26"	"894.09"	"9.17"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf18699"	"122704"	"ENSG00000172590"	"MRPL52"	"A6NMQ8; A8MXK5; A8MYI6; G3XCN9; hsa:122704; Q6NVH8; Q86TS9"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"14.4"	"12.8"	"16.1"	"17.3"	"21.9"	"19.6"	"29.9"	"32.4"	"33.6"	"36.9"	"65.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A8MWD9"	"Putative small nuclear ribonucleoprotein G-like protein 15 OS=Homo sapiens OX=9606 GN=SNRPGP15 PE=5 SV=2"	"26"	"3"	"7"	"3"	"76"	"8.5"	"8.84"	"1243.30"	"9.12"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	""	""	"SNRPGP15"	"A8MWD9"	""	""	"0"	"0"	"257.3"	"133.4"	"283.5"	"158.8"	"251.2"	"141.0"	"382.9"	"372.3"	"301.3"	"465.8"	"685.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00338"	"L-lactate dehydrogenase A chain OS=Homo sapiens OX=9606 GN=LDHA PE=1 SV=2"	"8"	"3"	"7"	"3"	"332"	"36.7"	"8.27"	"967.79"	"9.12"	"3"	"3"	"other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00056, Pf02866"	"3939"	"ENSG00000134333; ENSG00000288299"	"LDHA"	"B4DKQ2; B7Z5E3; D3DQY3; F8W819; hsa:3939; P00338; Q53G53; Q6IBM7; Q6ZNV1; Q9UDE8; Q9UDE9"	"Cori cycle; HIF1A and PPARG regulation of glycolysis; Photodynamic therapy-induced HIF-1 survival signaling; VEGFA-VEGFR2 signaling; Amino acid metabolism; Clear cell renal cell carcinoma pathways; PI3K/AKT/mTOR - vitamin D3 signaling; Metabolic reprogramming in colon cancer; Aerobic glycolysis; Glycolysis in senescence; Orexin receptor pathway; CCL18 signaling pathway; Glucose metabolism in triple-negative breast cancer cells; Warburg effect modulated by deubiquitinating enzymes and their substrates; Lactate shuttle in glial cells; Glycolysis and gluconeogenesis; A network map of Macrophage-stimulating protein (MSP) signaling; Metabolic Epileptic Disorders"	"Pyruvate metabolism"	"19"	"0"	"462.3"	"358.2"	"470.6"	"238.0"	"421.3"	"380.8"	"470.4"	"392.3"	"324.8"	"565.1"	"795.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NY12"	"H/ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1"	"13"	"3"	"6"	"3"	"217"	"22.3"	"10.92"	"880.85"	"9.11"	"3"	"3"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf04410"	"54433"	"ENSG00000109534"	"GAR1"	"hsa:54433; Q5MJQ2; Q9NY12"	""	"rRNA modification in the nucleus and cytosol; Telomere Extension By Telomerase"	"2"	"0"	"137.1"	"95.3"	"125.2"	"121.1"	"131.4"	"151.0"	"291.7"	"303.0"	"228.2"	"411.2"	"562.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IY18"	"Structural maintenance of chromosomes protein 5 OS=Homo sapiens OX=9606 GN=SMC5 PE=1 SV=2"	"6"	"5"	"6"	"5"	"1101"	"128.7"	"8.38"	"974.85"	"9.10"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463"	"23137"	"ENSG00000198887"	"SMC5"	"A6NM81; hsa:23137; O60335; Q05D92; Q5VZ60; Q8IY18; Q96SB9"	""	"SUMOylation of DNA damage response and repair proteins"	"1"	"0"	"26.4"	"12.0"	"26.3"	"21.9"	"24.6"	"25.7"	"40.6"	"43.2"	"35.4"	"56.0"	"71.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22087"	"rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2"	"10"	"3"	"6"	"3"	"321"	"33.8"	"10.18"	"923.44"	"9.07"	"3"	"3"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf01269"	"2091"	"ENSG00000105202; ENSG00000280548"	"FBL"	"B5BUE8; hsa:2091; O75259; P22087; Q6IAT5; Q9UPI6"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"114.3"	"62.5"	"76.3"	"77.6"	"86.4"	"96.4"	"240.2"	"231.2"	"202.9"	"373.7"	"487.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P40429"	"60S ribosomal protein L13a OS=Homo sapiens OX=9606 GN=RPL13A PE=1 SV=2"	"12"	"3"	"7"	"3"	"203"	"23.6"	"10.93"	"1159.78"	"9.05"	"3"	"2"	"protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00572"	"23521"	"ENSG00000142541"	"RPL13A"	"A8K505; hsa:23521; P40429"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"420.2"	"264.7"	"349.3"	"304.1"	"334.7"	"400.4"	"1420.3"	"1371.0"	"830.2"	"1497.5"	"1957.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00291"	"Huntingtin-interacting protein 1 OS=Homo sapiens OX=9606 GN=HIP1 PE=1 SV=5"	"2"	"3"	"5"	"3"	"1037"	"116.1"	"5.30"	"1078.72"	"9.04"	"3"	"2"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf01608, Pf07651, Pf16515"	"3092"	"ENSG00000127946"	"HIP1"	"B4E3I7; E7ES17; hsa:3092; O00291; O00328; Q2TB58; Q8TDL4; V5LU97"	"DYRK1A involvement regarding cell proliferation in brain development; 5q35 copy number variation"	"Clathrin-mediated endocytosis; ALK mutants bind TKIs; Signaling by ALK fusions and activated point mutants"	"5"	"0"	"44.0"	"22.5"	"29.5"	"33.8"	"27.0"	"41.8"	"64.8"	"60.3"	"42.7"	"66.0"	"99.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60907"	"F-box-like/WD repeat-containing protein TBL1X OS=Homo sapiens OX=9606 GN=TBL1X PE=1 SV=3"	"6"	"3"	"5"	"1"	"577"	"62.5"	"6.55"	"965.17"	"9.02"	"2"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400, Pf08513"	"6907"	"ENSG00000101849"	"TBL1X"	"A8K044; A8K4J7; hsa:6907; O60907; Q86UY2"	"Ectoderm differentiation; Ectoderm differentiation; Rett syndrome causing genes"	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; HCMV Early Events; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Heme signaling; BMAL1:CLOCK,NPAS2 activates circadian gene expression; Transcriptional activation of mitochondrial biogenesis; HDACs deacetylate histones; Cytoprotection by HMOX1; Activation of gene expression by SREBF (SREBP); NOTCH1 Intracellular Domain Regulates Transcription; Notch-HLH transcription pathway; Loss of MECP2 binding ability to the NCoR/SMRT complex; Regulation of MECP2 expression and activity; NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux; RORA activates gene expression"	"22"	"0"	"117.2"	"67.7"	"111.5"	"120.8"	"137.5"	"128.0"	"155.5"	"169.8"	"125.6"	"174.2"	"216.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02218"	"2-oxoglutarate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=OGDH PE=1 SV=3"	"4"	"3"	"6"	"3"	"1023"	"115.9"	"6.86"	"1040.60"	"9.01"	"3"	"3"	"protein metabolism;other metabolic processes;developmental processes"	"other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00676, Pf02779, Pf16078, Pf16870"	"4967"	"ENSG00000105953"	"OGDH"	"B4E2U9; D3DVL0; E9PBM1; hsa:4967; Q02218; Q96DD3; Q9UDX0"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Thiamine metabolic pathways; 7q11.23 copy number variation syndrome; TCA cycle (aka Krebs or citric acid cycle)"	"Glyoxylate metabolism and glycine degradation; Citric acid cycle (TCA cycle); Lysine catabolism"	"8"	"0"	"41.1"	"16.4"	"23.8"	"25.3"	"25.6"	"33.5"	"58.1"	"54.1"	"38.8"	"61.6"	"89.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NYJ1"	"Cytochrome c oxidase assembly factor 4 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=COA4 PE=1 SV=2"	"20"	"2"	"7"	"2"	"87"	"10.1"	"6.04"	"1788.48"	"8.97"	"2"	"1"	"cell organization and biogenesis"	"mitochondrion"	""	""	"51287"	"ENSG00000181924"	"COA4"	"B2RAA0; hsa:51287; Q69YU4; Q9NYJ1"	""	"Mitochondrial protein import"	"1"	"0"	"81.0"	"33.2"	"53.1"	"61.4"	"58.8"	"72.5"	"98.7"	"96.9"	"63.8"	"113.6"	"181.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16795"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFA9 PE=1 SV=2"	"8"	"2"	"4"	"2"	"377"	"42.5"	"9.80"	"960.80"	"8.96"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf01370"	"4704"	"ENSG00000139180"	"NDUFA9"	"hsa:4704; Q14076; Q16795; Q2NKX0"	"Electron transport chain: OXPHOS system in mitochondria; Ciliary landscape; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"6"	"0"	"67.8"	"52.6"	"59.4"	"53.3"	"63.9"	"70.8"	"118.6"	"94.0"	"66.9"	"138.5"	"161.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P28072"	"Proteasome subunit beta type-6 OS=Homo sapiens OX=9606 GN=PSMB6 PE=1 SV=4"	"13"	"3"	"6"	"3"	"239"	"25.3"	"4.92"	"941.79"	"8.95"	"2"	"3"	"protein metabolism;other metabolic processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00227"	"5694"	"ENSG00000142507"	"PSMB6"	"hsa:5694; P28072; Q96J55"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"62"	"0"	"273.6"	"198.2"	"290.9"	"303.2"	"263.1"	"279.2"	"759.0"	"729.0"	"621.3"	"994.5"	"1212.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HCS7"	"Pre-mRNA-splicing factor SYF1 OS=Homo sapiens OX=9606 GN=XAB2 PE=1 SV=2"	"4"	"3"	"5"	"3"	"855"	"99.9"	"6.23"	"888.89"	"8.93"	"2"	"3"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes"	"nucleus;other cell component"	""	"Pf13181"	"56949"	"ENSG00000076924"	"XAB2"	"hsa:56949; Q8TET6; Q96HB0; Q96IW0; Q9HCS7; Q9NRG6; Q9ULP3"	"Rett syndrome causing genes; Nucleotide excision repair in xeroderma pigmentosum"	"mRNA Splicing - Major Pathway; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	"7"	"0"	"110.8"	"96.0"	"129.1"	"111.0"	"153.7"	"148.8"	"245.3"	"238.2"	"162.2"	"280.3"	"312.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50991"	"T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4"	"9"	"4"	"8"	"4"	"539"	"57.9"	"7.83"	"1885.47"	"8.92"	"4"	"2"	"protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00118"	"10575"	"ENSG00000115484"	"CCT4"	"B2R6I3; B7Z8B1; F5H5W3; hsa:10575; O14870; P50991; Q53QP9; Q96C51"	"16p11.2 proximal deletion syndrome"	"Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"7"	"0"	"406.5"	"316.0"	"428.0"	"350.6"	"393.6"	"424.4"	"583.1"	"517.4"	"406.3"	"600.6"	"779.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P47755"	"F-actin-capping protein subunit alpha-2 OS=Homo sapiens OX=9606 GN=CAPZA2 PE=1 SV=3"	"19"	"3"	"6"	"3"	"286"	"32.9"	"5.85"	"951.80"	"8.91"	"3"	"3"	"cell organization and biogenesis"	"non-structural extracellular;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf01267"	"830"	"ENSG00000198898"	"CAPZA2"	"B4DG50; hsa:830; P47755"	""	"MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Sensory processing of sound by inner hair cells of the cochlea; Factors involved in megakaryocyte development and platelet production; Advanced glycosylation endproduct receptor signaling"	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62306"	"Small nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=SNRPF PE=1 SV=1"	"31"	"3"	"7"	"3"	"86"	"9.7"	"4.67"	"1141.49"	"8.91"	"3"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	"6636"	"ENSG00000139343"	"SNRPF"	"A2VCR2; B2R498; hsa:6636; P62306; Q15356; Q6IBQ1; Q6P4I0"	"mRNA processing"	"snRNP Assembly; mRNA Splicing - Major Pathway; SARS-CoV-2 modulates host translation machinery; mRNA Splicing - Minor Pathway; RNA Polymerase II Transcription Termination; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"8"	"0"	"256.2"	"166.2"	"233.1"	"165.7"	"158.0"	"262.9"	"689.5"	"673.1"	"500.8"	"854.8"	"1346.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49454"	"Centromere protein F OS=Homo sapiens OX=9606 GN=CENPF PE=1 SV=3"	"2"	"4"	"7"	"4"	"3114"	"357.3"	"5.10"	"1092.83"	"8.90"	"4"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf10473, Pf10481, Pf10490"	"1063"	"ENSG00000117724"	"CENPF"	"hsa:1063; P49454; Q13171; Q13246; Q5VVM7"	"Gastric cancer network 1; Ciliopathies"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Polo-like kinase mediated events"	"9"	"0"	"14.1"	"12.6"	"15.7"	"12.0"	"15.4"	"19.0"	"35.4"	"37.4"	"32.9"	"52.0"	"60.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86VP6"	"Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2"	"3"	"3"	"6"	"3"	"1230"	"136.3"	"5.78"	"898.71"	"8.89"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf08623"	"55832"	"ENSG00000111530"	"CAND1"	"B2RAU3; hsa:55832; O94918; Q6PIY4; Q86VP6; Q8NDJ4; Q96JZ9; Q96T19; Q9BTC4; Q9H0G2; Q9P0H7; Q9UF85"	"Endoderm differentiation"	"Neutrophil degranulation; Neddylation; Iron uptake and transport"	"4"	"0"	"44.2"	"23.9"	"49.5"	"36.7"	"44.3"	"41.4"	"96.9"	"96.0"	"87.3"	"141.5"	"194.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NTI5"	"Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens OX=9606 GN=PDS5B PE=1 SV=1"	"2"	"3"	"6"	"2"	"1447"	"164.6"	"8.47"	"999.57"	"8.89"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf20168"	"23047"	"ENSG00000083642"	"PDS5B"	"hsa:23047; Q5R3S3; Q5W0K8; Q6NSC3; Q8IXT6; Q9H5N8; Q9NTI5; Q9Y2I5; Q9Y451"	"Cohesin complex - Cornelia de Lange syndrome; 10q22q23 copy number variation"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"6"	"1"	"141.9"	"91.5"	"117.2"	"88.6"	"125.8"	"125.8"	"319.6"	"293.0"	"214.7"	"347.8"	"405.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q4G0J3"	"La-related protein 7 OS=Homo sapiens OX=9606 GN=LARP7 PE=1 SV=1"	"5"	"3"	"5"	"3"	"582"	"66.9"	"9.55"	"912.97"	"8.86"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf05383, Pf08777"	"51574"	"ENSG00000174720"	"LARP7"	"B2ZHN6; hsa:51574; Q3B7A9; Q4G0J3; Q9P1S7; Q9Y3Z8"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"138.6"	"82.6"	"120.1"	"110.6"	"117.8"	"111.6"	"230.3"	"206.2"	"118.5"	"230.6"	"329.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60953"	"Cell division control protein 42 homolog OS=Homo sapiens OX=9606 GN=CDC42 PE=1 SV=2"	"6"	"1"	"4"	"1"	"191"	"21.2"	"6.55"	"1023.22"	"8.84"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00071"	"998"	"ENSG00000070831"	"CDC42"	"hsa:998; P21181; P25763; P60953; Q7L8R5; Q9UDI2"	"Androgen receptor signaling pathway; Target of rapamycin signaling; Integrin-mediated cell adhesion; RANKL/RANK signaling pathway; Leptin signaling pathway; Microtubule cytoskeleton regulation; Metastatic brain tumor; Pathogenic Escherichia coli infection; RalA downstream regulated genes; B cell receptor signaling pathway; AGE/RAGE pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Spinal cord injury; Focal adhesion; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Oxidative damage response; p38 MAPK signaling pathway; Ebola virus infection in host; Ras signaling; Pancreatic adenocarcinoma pathway; EGF/EGFR signaling pathway; Nonalcoholic fatty liver disease; Hippo signaling regulation pathways; 22q11.2 copy number variation syndrome; Gastrin signaling pathway; Regulation of actin cytoskeleton; G13 signaling pathway; Genetic causes of porto-sinusoidal vascular disease; 13q12.12 copy number variation; T-cell receptor signaling pathway; DNA damage response (only ATM dependent)"	"RHO GTPases Activate Formins; MAPK6/MAPK4 signaling; RHO GTPases activate IQGAPs; RAC1 GTPase cycle; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; CDC42 GTPase cycle; RHOQ GTPase cycle; RHOG GTPase cycle; RHO GTPases Activate WASPs and WAVEs; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOJ GTPase cycle; RHOV GTPase cycle; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; RHOU GTPase cycle; EPHB-mediated forward signaling; DCC mediated attractive signaling; GPVI-mediated activation cascade; VEGFA-VEGFR2 Pathway; Myogenesis; Factors involved in megakaryocyte development and platelet production; G beta:gamma signalling through CDC42; EGFR downregulation; RHO GTPases activate PAKs; Inactivation of CDC42 and RAC1; CD28 dependent Vav1 pathway; RHO GTPases activate KTN1"	"61"	"0"	"516.4"	"221.1"	"344.2"	"302.2"	"357.6"	"334.5"	"466.7"	"396.6"	"282.3"	"531.7"	"878.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19525"	"Interferon-induced, double-stranded RNA-activated protein kinase OS=Homo sapiens OX=9606 GN=EIF2AK2 PE=1 SV=2"	"5"	"2"	"6"	"2"	"551"	"62.1"	"8.40"	"980.01"	"8.80"	"2"	"2"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;kinase activity;other molecular function"	"Pf00035, Pf00069"	"5610"	"ENSG00000055332"	"EIF2AK2"	"A8K3P0; D6W584; E9PC80; hsa:5610; P19525; Q52M43; Q7Z6F6; Q9UIR4"	"Translation factors; Alzheimer's disease and miRNA effects; Ebola virus infection in host; Measles virus infection; Type I interferon induction and signaling during SARS-CoV-2 infection; Host-pathogen interaction of human coronaviruses - interferon induction; Alzheimer's disease; Roles of ceramides in development of insulin resistance; Type II interferon signaling"	"ISG15 antiviral mechanism; Interferon alpha/beta signaling; Inhibition of PKR"	"12"	"0"	"40.5"	"19.9"	"41.9"	"40.1"	"36.2"	"48.0"	"135.4"	"121.2"	"98.9"	"152.6"	"176.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2S6"	"Translation machinery-associated protein 7 OS=Homo sapiens OX=9606 GN=TMA7 PE=1 SV=1"	"36"	"4"	"9"	"3"	"64"	"7.1"	"9.99"	"1983.24"	"8.78"	"4"	"2"	""	""	""	"Pf09072"	"51372"	"ENSG00000232112"	"TMA7"	"hsa:51372; Q9P052; Q9Y2S6"	""	""	"0"	"1"	"641.3"	"247.7"	"448.1"	"431.5"	"544.2"	"408.7"	"3648.8"	"3113.5"	"2535.2"	"3579.9"	"5523.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NXW9"	"Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 OS=Homo sapiens OX=9606 GN=ALKBH4 PE=1 SV=1"	"7"	"2"	"6"	"2"	"302"	"33.8"	"6.67"	"890.44"	"8.78"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"cytoskeletal activity;other molecular function"	""	"54784"	"ENSG00000160993"	"ALKBH4"	"hsa:54784; Q53H92; Q9H6A4; Q9NXW9"	""	""	"0"	"0"	"206.2"	"166.9"	"251.2"	"243.5"	"244.6"	"227.7"	"350.4"	"366.1"	"328.0"	"503.9"	"681.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O76021"	"Ribosomal L1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RSL1D1 PE=1 SV=3"	"12"	"4"	"7"	"4"	"490"	"54.9"	"10.13"	"1420.69"	"8.76"	"4"	"3"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00687"	"26156"	"ENSG00000171490"	"RSL1D1"	"B4DJ58; D3DUG7; hsa:26156; O76021; Q2M1T7; Q6PL22; Q8IWS7; Q8WUZ1; Q9HDA9; Q9Y3Z9"	""	""	"0"	"0"	"60.7"	"40.5"	"49.5"	"48.6"	"47.7"	"62.1"	"175.3"	"161.6"	"126.3"	"202.4"	"229.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P38432"	"Coilin OS=Homo sapiens OX=9606 GN=COIL PE=1 SV=1"	"7"	"4"	"7"	"4"	"576"	"62.6"	"9.07"	"1160.39"	"8.75"	"4"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf15862"	"8161"	"ENSG00000121058"	"COIL"	"B2R931; hsa:8161; P38432"	""	""	"0"	"0"	"167.0"	"98.9"	"159.9"	"142.1"	"120.4"	"162.4"	"345.3"	"331.4"	"245.8"	"385.0"	"541.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P56537"	"Eukaryotic translation initiation factor 6 OS=Homo sapiens OX=9606 GN=EIF6 PE=1 SV=1"	"10"	"2"	"4"	"2"	"245"	"26.6"	"4.68"	"235.22"	"8.75"	"1"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf01912"	"3692"	"ENSG00000242372"	"EIF6"	"B7ZBG9; hsa:3692; P56537; Q6IBN8; Q96TD5"	"Translation factors; Genetic causes of porto-sinusoidal vascular disease"	""	"2"	"0"	"200.0"	"120.9"	"174.1"	"152.6"	"173.2"	"177.5"	"548.1"	"470.9"	"353.1"	"517.9"	"744.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y266"	"Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1"	"12"	"4"	"8"	"4"	"331"	"38.2"	"5.38"	"1748.11"	"8.73"	"4"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf04969, Pf14050, Pf16273"	"10726"	"ENSG00000090273"	"NUDC"	"hsa:10726; Q5QP31; Q5QP35; Q9H0N2; Q9Y266; Q9Y2B6"	"Ciliary landscape; PAFAH1B1 copy number variation"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; RND2 GTPase cycle; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"9"	"0"	"411.6"	"219.5"	"303.7"	"307.6"	"296.6"	"331.3"	"635.7"	"536.6"	"384.9"	"605.3"	"1029.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NTK5"	"Obg-like ATPase 1 OS=Homo sapiens OX=9606 GN=OLA1 PE=1 SV=2"	"8"	"3"	"6"	"3"	"396"	"44.7"	"7.81"	"1005.43"	"8.70"	"3"	"3"	"other metabolic processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cell component"	"translation activity;other molecular function"	"Pf01926, Pf06071"	"29789"	"ENSG00000138430"	"OLA1"	"D7EHM2; hsa:29789; Q5BJD7; Q8NCI8; Q96CU1; Q96SV2; Q9NTK5; Q9P1D3; Q9UNY9; Q9Y6G4"	""	"Platelet degranulation"	"1"	"0"	"245.4"	"131.3"	"254.4"	"234.2"	"292.0"	"270.8"	"444.6"	"421.4"	"294.9"	"490.0"	"697.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14579"	"Coatomer subunit epsilon OS=Homo sapiens OX=9606 GN=COPE PE=1 SV=3"	"14"	"3"	"6"	"3"	"308"	"34.5"	"5.12"	"881.67"	"8.69"	"3"	"3"	"transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus"	"other molecular function"	"Pf04733"	"11316"	"ENSG00000105669"	"COPE"	"A6NE29; A6NKA3; hsa:11316; O14579; O76097; Q6IBB8; Q9UGP6"	""	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport"	"2"	"0"	"70.1"	"45.7"	"73.3"	"74.7"	"94.1"	"92.7"	"182.0"	"176.5"	"123.8"	"197.3"	"270.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49915"	"GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1"	"7"	"4"	"6"	"4"	"693"	"76.7"	"6.87"	"1050.12"	"8.68"	"3"	"3"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00117, Pf00958, Pf02540"	"8833"	"ENSG00000163655"	"GMPS"	"A8K639; B4DXV7; F8W720; hsa:8833; P49915"	""	"Purine ribonucleoside monophosphate biosynthesis; Azathioprine ADME"	"2"	"0"	"224.2"	"134.3"	"209.6"	"148.5"	"186.3"	"182.9"	"260.9"	"220.1"	"147.6"	"282.4"	"401.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UPT8"	"Zinc finger CCCH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=ZC3H4 PE=1 SV=3"	"5"	"4"	"6"	"4"	"1303"	"140.2"	"6.27"	"954.52"	"8.68"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00642, Pf14608, Pf18044"	"23211"	"ENSG00000130749"	"ZC3H4"	"hsa:23211; Q9UPT8; Q9Y420"	""	""	"0"	"0"	"45.9"	"44.3"	"50.1"	"41.2"	"41.6"	"56.6"	"101.8"	"86.9"	"65.8"	"94.1"	"103.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96C36"	"Pyrroline-5-carboxylate reductase 2 OS=Homo sapiens OX=9606 GN=PYCR2 PE=1 SV=1"	"15"	"3"	"6"	"2"	"320"	"33.6"	"7.77"	"997.40"	"8.66"	"3"	"3"	"other metabolic processes;stress response"	"mitochondrion"	"other molecular function"	"Pf03807, Pf14748"	"29920"	"ENSG00000143811"	"PYCR2"	"A8K798; hsa:29920; Q7Z515; Q96C36; Q9Y5J4"	"Metabolic reprogramming in colon cancer"	"Glutamate and glutamine metabolism"	"2"	"0"	"16.5"	"11.1"	"20.3"	"35.2"	"30.0"	"22.9"	"35.3"	"39.0"	"29.6"	"42.2"	"55.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H2K8"	"Serine/threonine-protein kinase TAO3 OS=Homo sapiens OX=9606 GN=TAOK3 PE=1 SV=2"	"4"	"3"	"6"	"1"	"898"	"105.3"	"7.30"	"922.14"	"8.63"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069"	"51347"	"ENSG00000135090"	"TAOK3"	"hsa:51347; Q658N1; Q8IUM4; Q9H2K8; Q9HC79; Q9NZM9; Q9UHG7"	"MAPK signaling pathway"	"RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle"	"4"	"0"	"11.8"	"5.1"	"8.9"	"6.7"	"8.7"	"7.2"	"20.3"	"33.7"	"23.9"	"39.0"	"50.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N6N3"	"UPF0690 protein C1orf52 OS=Homo sapiens OX=9606 GN=C1orf52 PE=1 SV=1"	"13"	"2"	"4"	"2"	"182"	"20.6"	"5.21"	"874.37"	"8.52"	"2"	"2"	""	"nucleus"	""	"Pf15559"	"148423"	"ENSG00000162642"	"C1orf52"	"B3KX89; hsa:148423; Q8N6N3; Q8TDK5; Q8TDK6"	""	""	"0"	"0"	"72.1"	"42.6"	"58.8"	"54.5"	"56.5"	"78.4"	"113.9"	"103.0"	"74.7"	"111.8"	"155.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P21953"	"2-oxoisovalerate dehydrogenase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=BCKDHB PE=1 SV=2"	"10"	"3"	"6"	"3"	"392"	"43.1"	"6.29"	"898.87"	"8.52"	"3"	"3"	"other metabolic processes;other biological processes"	"mitochondrion;nucleus"	"other molecular function"	"Pf02779, Pf02780"	"594"	"ENSG00000083123"	"BCKDHB"	"hsa:594; P21953; Q5T2J3; Q9BQL0"	"Primary ovarian insufficiency"	"Glyoxylate metabolism and glycine degradation; Branched-chain amino acid catabolism"	"3"	"0"	"72.8"	"62.7"	"82.5"	"85.2"	"88.2"	"88.2"	"167.6"	"155.7"	"119.5"	"171.8"	"197.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P54725"	"UV excision repair protein RAD23 homolog A OS=Homo sapiens OX=9606 GN=RAD23A PE=1 SV=1"	"6"	"3"	"7"	"1"	"363"	"39.6"	"4.58"	"1206.76"	"8.50"	"3"	"2"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00240, Pf00627, Pf09280"	"5886"	"ENSG00000179262"	"RAD23A"	"hsa:5886; K7ESE3; P54725; Q59EU8; Q5M7Z1"	"Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"Josephin domain DUBs; Formation of Incision Complex in GG-NER; DNA Damage Recognition in GG-NER"	"6"	"0"	"152.5"	"82.9"	"125.5"	"99.6"	"130.1"	"142.1"	"207.8"	"172.1"	"137.3"	"249.5"	"345.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P83876"	"Thioredoxin-like protein 4A OS=Homo sapiens OX=9606 GN=TXNL4A PE=1 SV=1"	"27"	"3"	"5"	"3"	"142"	"16.8"	"5.85"	"810.32"	"8.49"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;cytosol;nucleus"	""	"Pf02966"	"10907"	"ENSG00000141759"	"TXNL4A"	"B2RC18; hsa:10907; O14834; P83876"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"0"	"205.1"	"111.3"	"163.6"	"162.1"	"166.9"	"155.7"	"305.2"	"260.4"	"187.7"	"300.8"	"453.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95747"	"Serine/threonine-protein kinase OSR1 OS=Homo sapiens OX=9606 GN=OXSR1 PE=1 SV=1"	"8"	"3"	"4"	"3"	"527"	"58.0"	"6.43"	"429.85"	"8.49"	"1"	"3"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf12202"	"9943"	"ENSG00000172939"	"OXSR1"	"hsa:9943; O95747; Q3LR53; Q7Z501; Q9UPQ1"	""	""	"0"	"0"	"71.0"	"34.3"	"54.5"	"62.6"	"61.5"	"66.0"	"129.0"	"91.0"	"76.6"	"167.4"	"606.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15437"	"Protein transport protein Sec23B OS=Homo sapiens OX=9606 GN=SEC23B PE=1 SV=2"	"3"	"2"	"7"	"1"	"767"	"86.4"	"6.89"	"1246.05"	"8.46"	"2"	"2"	"cell organization and biogenesis;transport"	"other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00626, Pf04810, Pf04811, Pf04815, Pf08033"	"10483"	"ENSG00000101310"	"SEC23B"	"D3DW33; hsa:10483; Q15437; Q503A9; Q5W183; Q9BS15; Q9BSI2; Q9H1D7"	"Sterol regulatory element-binding proteins (SREBP) signaling"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09471"	"Guanine nucleotide-binding protein G(o) subunit alpha OS=Homo sapiens OX=9606 GN=GNAO1 PE=1 SV=4"	"12"	"3"	"6"	"1"	"354"	"40.0"	"5.53"	"1034.08"	"8.41"	"3"	"3"	"signal transduction;other biological processes"	"plasma membrane;other membranes"	"signal transduction activity or receptor binding;other molecular function"	"Pf00503"	"2775"	"ENSG00000087258"	"GNAO1"	"hsa:2775; P09471; P29777; Q8TD72; Q9UMV4"	"Thyroid stimulating hormone (TSH) signaling pathway; Corticotropin-releasing hormone signaling pathway; G protein signaling pathways; Rett syndrome causing genes; Male infertility; Purinergic signaling; Calcium regulation in cardiac cells; Serotonin HTR1 group and FOS pathway"	"Ca2+ pathway"	"9"	"0"	"5.7"	"4.8"	"5.7"	"7.0"	"1.7"	"5.4"	"14.9"	"22.2"	"18.6"	"21.7"	"25.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NEY8"	"Periphilin-1 OS=Homo sapiens OX=9606 GN=PPHLN1 PE=1 SV=2"	"5"	"3"	"6"	"3"	"458"	"52.7"	"9.11"	"938.03"	"8.39"	"2"	"2"	"cell organization and biogenesis;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	""	"Pf11488"	"51535"	"ENSG00000134283"	"PPHLN1"	"E9PAX8; hsa:51535; Q86YT2; Q8IXN3; Q8NEY8; Q8TB09; Q96NB9; Q9NXL4; Q9P0P6; Q9P0R9"	""	""	"0"	"0"	"575.2"	"345.6"	"432.2"	"458.3"	"462.7"	"559.6"	"1019.8"	"901.1"	"668.2"	"1051.6"	"1373.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P38606"	"V-type proton ATPase catalytic subunit A OS=Homo sapiens OX=9606 GN=ATP6V1A PE=1 SV=2"	"5"	"2"	"4"	"2"	"617"	"68.3"	"5.52"	"909.81"	"8.38"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00006, Pf02874, Pf16886"	"523"	"ENSG00000114573"	"ATP6V1A"	"B2RBR8; B7Z1R5; D3DN75; hsa:523; P38606; Q53YD9; Q96DY6; Q9UHY3"	"Proximal tubule transport"	"Amino acids regulate mTORC1; ROS and RNS production in phagocytes; Insulin receptor recycling; Transferrin endocytosis and recycling; Ion channel transport"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15144"	"Actin-related protein 2/3 complex subunit 2 OS=Homo sapiens OX=9606 GN=ARPC2 PE=1 SV=1"	"8"	"3"	"4"	"3"	"300"	"34.3"	"7.36"	"305.50"	"8.37"	"1"	"3"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity"	"Pf04045"	"10109"	"ENSG00000163466"	"ARPC2"	"hsa:10109; O15144; Q92801; Q9P1D4"	"Pathogenic Escherichia coli infection"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"6"	"0"	"91.0"	"69.4"	"116.1"	"91.8"	"105.7"	"124.4"	"265.8"	"305.7"	"288.6"	"611.2"	"1433.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UJZ1"	"Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2 PE=1 SV=1"	"8"	"2"	"4"	"2"	"356"	"38.5"	"7.39"	"1007.64"	"8.35"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;mitochondrion"	"signal transduction activity or receptor binding;other molecular function"	"Pf01145, Pf16200"	"30968"	"ENSG00000165283"	"STOML2"	"B4E1K7; D3DRN3; hsa:30968; O60376; Q53G29; Q96FY2; Q9P042; Q9UJZ1"	""	"Processing of SMDT1"	"1"	"0"	"71.5"	"44.5"	"74.9"	"47.2"	"62.7"	"61.3"	"97.8"	"82.0"	"63.2"	"115.9"	"169.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00341"	"Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2"	"3"	"3"	"5"	"3"	"1268"	"141.4"	"6.87"	"600.95"	"8.29"	"2"	"3"	"other metabolic processes;transport"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013"	"3069"	"ENSG00000115677"	"HDLBP"	"B4DTQ2; E7EM71; hsa:3069; Q00341; Q53QU2; Q9UCY3"	"2q37 copy number variation syndrome"	"HDL clearance"	"2"	"0"	"38.7"	"26.6"	"29.6"	"25.5"	"26.3"	"34.0"	"111.7"	"93.1"	"82.5"	"94.7"	"142.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13620"	"Cullin-4B OS=Homo sapiens OX=9606 GN=CUL4B PE=1 SV=4"	"3"	"3"	"6"	"1"	"913"	"103.9"	"7.37"	"1215.68"	"8.29"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00888, Pf10557"	"8450"	"ENSG00000158290"	"CUL4B"	"B1APK5; B3KVX4; B7Z5K8; hsa:8450; Q13620; Q6PIE4; Q6UP07; Q7Z673; Q9BY37; Q9UEB7; Q9UED7"	"Mesodermal commitment pathway; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"Neddylation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; DNA Damage Recognition in GG-NER; Dual Incision in GG-NER"	"13"	"2"	"187.3"	"103.7"	"143.0"	"142.6"	"153.4"	"164.9"	"247.6"	"216.8"	"155.0"	"273.0"	"476.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8ND56"	"Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3"	"8"	"3"	"6"	"3"	"463"	"50.5"	"9.52"	"928.36"	"8.28"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;signal transduction;other biological processes"	"cytosol;cytoskeleton;other cell component"	"nucleic acid binding activity"	"Pf09532, Pf12701"	"26065"	"ENSG00000257103; ENSG00000262860"	"LSM14A"	"B4DTG6; hsa:26065; Q76LX7; Q8ND56; Q96AR3; Q96K73; Q96SN5; Q9UFR3"	""	""	"0"	"0"	"254.9"	"125.9"	"199.5"	"232.5"	"230.8"	"230.9"	"500.4"	"445.0"	"312.6"	"506.8"	"710.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UJV9"	"Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2"	"6"	"3"	"6"	"3"	"622"	"69.8"	"6.84"	"1063.41"	"8.27"	"3"	"3"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00270, Pf00271"	"51428"	"ENSG00000183258"	"DDX41"	"B2RDC8; hsa:51428; Q96BK6; Q96K05; Q9NT96; Q9NW04; Q9UJV9"	"5q35 copy number variation"	"mRNA Splicing - Major Pathway; Regulation of innate immune responses to cytosolic DNA; IRF3-mediated induction of type I IFN"	"5"	"0"	"59.2"	"42.5"	"66.1"	"63.8"	"60.4"	"58.4"	"222.8"	"200.9"	"111.3"	"184.4"	"204.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6ZYL4"	"General transcription factor IIH subunit 5 OS=Homo sapiens OX=9606 GN=GTF2H5 PE=1 SV=1"	"41"	"2"	"3"	"2"	"71"	"8.0"	"4.65"	"424.91"	"8.27"	"1"	"2"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	""	"Pf06331"	"404672"	"ENSG00000272047"	"GTF2H5"	"hsa:404672; Q0P5V8; Q6ZYL4"	"Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"NoRC negatively regulates rRNA expression; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; Formation of Incision Complex in GG-NER; Dual Incision in GG-NER"	"32"	"0"	"32.9"	"21.4"	"37.5"	"32.1"	"32.9"	"33.7"	"74.6"	"132.3"	"136.0"	"264.9"	"353.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60231"	"Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2"	"3"	"3"	"6"	"3"	"1041"	"119.2"	"6.80"	"927.60"	"8.27"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"8449"	"ENSG00000204560; ENSG00000206486; ENSG00000226171; ENSG00000231377; ENSG00000233049; ENSG00000233418; ENSG00000233561"	"DHX16"	"hsa:8449; O60231; O60322; Q5JP45; Q969X7; Q96QC1"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"100.7"	"55.5"	"78.4"	"93.0"	"89.3"	"102.0"	"266.9"	"270.3"	"202.5"	"277.2"	"424.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14174"	"Macrophage migration inhibitory factor OS=Homo sapiens OX=9606 GN=MIF PE=1 SV=4"	"11"	"2"	"6"	"2"	"115"	"12.5"	"7.88"	"916.81"	"8.23"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01187"	"4282"	"ENSG00000240972; ENSG00000276701"	"MIF"	"A5Z1R8; B2R4S3; hsa:4282; P14174; Q2V4Y5; Q6FHV0"	"Adipogenesis; Spinal cord injury"	"Neutrophil degranulation; Cell surface interactions at the vascular wall; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"5"	"0"	"141.4"	"177.2"	"191.1"	"113.7"	"146.8"	"229.9"	"190.1"	"148.2"	"111.2"	"206.8"	"261.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75380"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS6 PE=1 SV=1"	"18"	"2"	"4"	"2"	"124"	"13.7"	"8.28"	"966.11"	"8.23"	"2"	"2"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf10276"	"4726"	"ENSG00000145494"	"NDUFS6"	"hsa:4726; O75380"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"236.1"	"171.2"	"203.6"	"165.4"	"199.6"	"222.8"	"388.5"	"337.9"	"273.7"	"468.4"	"522.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q07065"	"Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2"	"4"	"2"	"4"	"2"	"602"	"66.0"	"5.92"	"939.08"	"8.21"	"2"	"2"	""	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	""	""	"10970"	"ENSG00000136026"	"CKAP4"	"hsa:10970; Q07065; Q504S5; Q53ES6"	""	"Neutrophil degranulation; RND2 GTPase cycle; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; RND3 GTPase cycle; Surfactant metabolism"	"6"	"0"	"62.0"	"38.4"	"67.4"	"50.7"	"67.4"	"63.5"	"136.0"	"102.7"	"70.4"	"145.5"	"163.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99436"	"Proteasome subunit beta type-7 OS=Homo sapiens OX=9606 GN=PSMB7 PE=1 SV=1"	"7"	"2"	"5"	"2"	"277"	"29.9"	"7.68"	"740.12"	"8.18"	"2"	"2"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00227, Pf12465"	"5695"	"ENSG00000136930"	"PSMB7"	"B4E0P1; hsa:5695; Q5TBG6; Q96AG8; Q99436; Q9BWA7"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"ER-Phagosome pathway; Neutrophil degranulation; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"63"	"0"	"261.8"	"151.7"	"235.2"	"229.0"	"240.9"	"235.6"	"622.8"	"589.9"	"480.0"	"653.9"	"825.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HAU0"	"Pleckstrin homology domain-containing family A member 5 OS=Homo sapiens OX=9606 GN=PLEKHA5 PE=1 SV=1"	"2"	"3"	"5"	"3"	"1116"	"127.4"	"7.53"	"763.22"	"8.18"	"2"	"3"	"developmental processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00169, Pf00397"	"54477"	"ENSG00000052126"	"PLEKHA5"	"A0JP03; B4DGS1; E9PHQ3; F5H0I0; hsa:54477; Q6NSF8; Q86ST7; Q8N3K6; Q96DY9; Q9BVR4; Q9C0H7; Q9H924; Q9HAU0; Q9NVK8"	""	"Synthesis of PIPs at the plasma membrane"	"1"	"0"	"100.3"	"82.5"	"122.3"	"110.5"	"123.0"	"113.4"	"243.4"	"237.3"	"201.9"	"277.7"	"330.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P56545"	"C-terminal-binding protein 2 OS=Homo sapiens OX=9606 GN=CTBP2 PE=1 SV=1"	"7"	"3"	"6"	"2"	"445"	"48.9"	"6.95"	"978.89"	"8.15"	"3"	"3"	"cell-cell signaling;cell organization and biogenesis;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00389, Pf02826"	"1488"	"ENSG00000175029"	"CTBP2"	"A8K2X5; D3DRF5; hsa:1488; O43449; P56545; Q5SQP7; Q69YI3; Q86SV0; Q8IY44; Q9H2T8"	"Neural crest differentiation; Notch signaling; Mesodermal commitment pathway; Wnt signaling pathway and pluripotency; lncRNA in canonical Wnt signaling and colorectal cancer; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Ciliary landscape; Pleural mesothelioma"	"Repression of WNT target genes; Signaling by TCF7L2 mutants"	"11"	"1"	"346.7"	"204.1"	"356.5"	"351.2"	"387.0"	"419.2"	"590.5"	"560.0"	"377.5"	"483.7"	"580.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35606"	"Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2"	"4"	"3"	"5"	"3"	"906"	"102.4"	"5.27"	"900.82"	"8.13"	"2"	"3"	"transport"	"other membranes;cytosol;ER/Golgi"	"other molecular function"	"Pf00400, Pf04053"	"9276"	"ENSG00000184432"	"COPB2"	"B4DZI8; hsa:9276; P35606"	""	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport"	"2"	"0"	"166.1"	"104.8"	"147.0"	"153.1"	"182.0"	"176.0"	"276.7"	"293.6"	"228.6"	"346.7"	"473.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22314"	"Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3"	"3"	"3"	"6"	"3"	"1058"	"117.8"	"5.76"	"1039.74"	"8.13"	"3"	"3"	"protein metabolism;other metabolic processes;stress response"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00899, Pf09358, Pf10585, Pf16190, Pf16191"	"7317"	"ENSG00000130985"	"UBA1"	"hsa:7317; P22314; Q5JRR8; Q96E13"	"Proteasome degradation; Parkin-ubiquitin proteasomal system pathway; Parkinson's disease pathway"	"Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Antigen processing: Ubiquitination & Proteasome degradation"	"5"	"0"	"365.8"	"291.3"	"399.6"	"199.4"	"322.5"	"308.6"	"333.2"	"248.8"	"166.3"	"422.4"	"500.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UPN6"	"SR-related and CTD-associated factor 8 OS=Homo sapiens OX=9606 GN=SCAF8 PE=1 SV=1"	"3"	"3"	"6"	"1"	"1271"	"140.4"	"8.29"	"976.50"	"8.12"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf04818"	"22828"	"ENSG00000213079"	"SCAF8"	"B7Z888; hsa:22828; Q5TBU6; Q6NSK3; Q9BQN8; Q9BX43; Q9UPN6"	""	""	"0"	"0"	"18.5"	"13.0"	"13.9"	"18.2"	"18.3"	"16.9"	"36.9"	"42.5"	"31.6"	"49.1"	"65.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15942"	"Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1"	"5"	"2"	"5"	"2"	"572"	"61.2"	"6.67"	"697.58"	"8.10"	"2"	"2"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00412"	"7791"	"ENSG00000159840; ENSG00000285443"	"ZYX"	"A4D2G6; B4DQX7; hsa:7791; Q15942; Q6I9S4"	"Integrin-mediated cell adhesion; Focal adhesion"	""	"2"	"0"	"53.0"	"45.9"	"54.2"	"53.5"	"56.3"	"55.0"	"81.8"	"74.7"	"57.9"	"75.6"	"87.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P59998"	"Actin-related protein 2/3 complex subunit 4 OS=Homo sapiens OX=9606 GN=ARPC4 PE=1 SV=3"	"16"	"3"	"5"	"3"	"168"	"19.7"	"8.43"	"703.33"	"8.08"	"2"	"3"	"cell organization and biogenesis"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf05856"	"10093"	"ENSG00000241553"	"ARPC4"	"C9JWM7; E7ETI0; F6TTL5; hsa:10093; O15509; P59998; Q6P0W5; Q96QJ3"	"Pathogenic Escherichia coli infection"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"6"	"0"	"92.0"	"61.2"	"107.1"	"82.6"	"101.3"	"98.2"	"219.1"	"330.2"	"306.9"	"607.4"	"1498.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NVM6"	"DnaJ homolog subfamily C member 17 OS=Homo sapiens OX=9606 GN=DNAJC17 PE=1 SV=1"	"10"	"2"	"4"	"2"	"304"	"34.7"	"8.53"	"825.77"	"8.06"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf00226"	"55192"	"ENSG00000104129"	"DNAJC17"	"hsa:55192; Q9NVM6"	""	""	"0"	"0"	"15.6"	"9.6"	"14.2"	"14.5"	"18.8"	"13.8"	"68.9"	"72.2"	"66.6"	"118.2"	"243.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BTE3"	"Mini-chromosome maintenance complex-binding protein OS=Homo sapiens OX=9606 GN=MCMBP PE=1 SV=2"	"10"	"3"	"4"	"3"	"642"	"72.9"	"5.87"	"637.46"	"8.05"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf09739"	"79892"	"ENSG00000197771"	"MCMBP"	"B3KSP7; hsa:79892; Q6IA56; Q9BTE3; Q9BVT9; Q9H916"	""	""	"0"	"0"	"46.9"	"32.0"	"39.5"	"45.0"	"39.8"	"39.9"	"69.0"	"76.6"	"52.6"	"57.5"	"93.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99547"	"M-phase phosphoprotein 6 OS=Homo sapiens OX=9606 GN=MPHOSPH6 PE=1 SV=2"	"14"	"3"	"6"	"3"	"160"	"19.0"	"5.20"	"907.99"	"8.05"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf10175"	"10200"	"ENSG00000135698"	"MPHOSPH6"	"B2RAF0; hsa:10200; Q99547"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"314.9"	"167.9"	"347.1"	"230.5"	"266.9"	"283.9"	"656.6"	"613.8"	"432.1"	"653.8"	"893.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14257"	"Reticulocalbin-2 OS=Homo sapiens OX=9606 GN=RCN2 PE=1 SV=1"	"11"	"2"	"3"	"2"	"317"	"36.9"	"4.40"	"747.36"	"8.04"	"1"	"2"	""	"ER/Golgi;nucleus"	"other molecular function"	"Pf13202"	"5955"	"ENSG00000117906"	"RCN2"	"A8MTG6; F8WCY5; hsa:5955; Q14257; Q53XN8"	""	""	"0"	"0"	"16.4"	"9.0"	"17.2"	"17.6"	"20.1"	"20.2"	"50.7"	"51.9"	"38.6"	"57.6"	"66.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5JRX3"	"Presequence protease, mitochondrial OS=Homo sapiens OX=9606 GN=PITRM1 PE=1 SV=3"	"3"	"3"	"5"	"3"	"1037"	"117.3"	"6.92"	"667.92"	"8.02"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport"	"mitochondrion"	"enzyme regulator activity;other molecular function"	"Pf00675, Pf05193, Pf08367"	"10531"	"ENSG00000107959"	"PITRM1"	"B3KMJ6; B4E0J8; C9JSL2; E7ES23; hsa:10531; O95204; Q2M2G6; Q4VBR1; Q5JRW7; Q5JRX3; Q7L5Z7; Q9BSI6; Q9BVJ5; Q9UPP8"	""	"Mitochondrial protein import"	"1"	"0"	"70.8"	"50.3"	"80.1"	"67.3"	"60.9"	"78.7"	"107.4"	"117.0"	"117.6"	"272.1"	"988.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UEY8"	"Gamma-adducin OS=Homo sapiens OX=9606 GN=ADD3 PE=1 SV=1"	"6"	"3"	"5"	"3"	"706"	"79.1"	"6.32"	"1098.24"	"8.02"	"3"	"2"	"cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00596"	"120"	"ENSG00000148700"	"ADD3"	"D3DRA8; hsa:120; O43243; Q5VU09; Q92773; Q9UEY7; Q9UEY8"	""	"Miscellaneous transport and binding events; RHOD GTPase cycle; RHOF GTPase cycle"	"3"	"0"	"62.4"	"41.8"	"56.2"	"51.6"	"53.0"	"62.8"	"126.5"	"124.8"	"99.6"	"163.2"	"209.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55786"	"Puromycin-sensitive aminopeptidase OS=Homo sapiens OX=9606 GN=NPEPPS PE=1 SV=2"	"3"	"3"	"5"	"3"	"919"	"103.2"	"5.72"	"545.88"	"7.98"	"2"	"3"	"protein metabolism;other metabolic processes;stress response"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01433, Pf11838, Pf17900"	"9520"	"ENSG00000141279"	"NPEPPS"	"B7Z463; hsa:9520; P55786; Q6P145; Q9NP16; Q9UEM2"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	"135.1"	"104.0"	"169.2"	"106.8"	"133.5"	"145.8"	"175.1"	"160.0"	"127.7"	"197.8"	"351.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P84098"	"60S ribosomal protein L19 OS=Homo sapiens OX=9606 GN=RPL19 PE=1 SV=1"	"16"	"3"	"5"	"2"	"196"	"23.5"	"11.47"	"1070.56"	"7.93"	"3"	"2"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01280"	"6143"	"ENSG00000108298"	"RPL19"	"B2R4K2; hsa:6143; P14118; P22908; P84098; Q502Y6; Q7Z6E4"	"Cytoplasmic ribosomal proteins"	"SRP-dependent cotranslational protein targeting to membrane; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"164.3"	"123.3"	"147.8"	"130.3"	"150.7"	"150.2"	"540.6"	"510.2"	"410.6"	"558.7"	"551.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O96019"	"Actin-like protein 6A OS=Homo sapiens OX=9606 GN=ACTL6A PE=1 SV=1"	"9"	"3"	"6"	"3"	"429"	"47.4"	"5.60"	"934.57"	"7.92"	"3"	"3"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00022"	"86"	"ENSG00000136518"	"ACTL6A"	"B3KMN1; D3DNR9; hsa:86; O96019; Q8TAE5; Q9BVS8; Q9H0W6"	"Androgen receptor network in prostate cancer; Gastric cancer network 1; Tumor suppressor activity of SMARCB1; Thermogenesis; Kleefstra syndrome"	"UCH proteinases; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; RMTs methylate histone arginines; HATs acetylate histones; DNA Damage Recognition in GG-NER"	"10"	"0"	"96.4"	"47.2"	"76.2"	"42.2"	"68.4"	"76.2"	"82.4"	"65.8"	"45.3"	"91.3"	"162.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BWU0"	"Kanadaptin OS=Homo sapiens OX=9606 GN=SLC4A1AP PE=1 SV=1"	"6"	"5"	"8"	"5"	"796"	"88.8"	"5.19"	"1844.94"	"7.85"	"5"	"3"	""	"plasma membrane;other membranes;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00498"	"22950"	"ENSG00000163798"	"SLC4A1AP"	"A6NJ39; hsa:22950; Q4KMT1; Q4KMX0; Q7Z5Q9; Q9BWU0; Q9NVN2"	""	""	"0"	"0"	"248.0"	"157.2"	"248.5"	"210.4"	"242.9"	"225.6"	"547.2"	"487.6"	"333.3"	"454.7"	"628.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61163"	"Alpha-centractin OS=Homo sapiens OX=9606 GN=ACTR1A PE=1 SV=1"	"9"	"3"	"5"	"2"	"376"	"42.6"	"6.64"	"616.68"	"7.85"	"2"	"3"	"transport"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00022"	"10121"	"ENSG00000138107"	"ACTR1A"	"B2R6B0; hsa:10121; P42024; P61163"	""	"COPI-mediated anterograde transport; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; MHC class II antigen presentation; COPI-independent Golgi-to-ER retrograde traffic"	"11"	"0"	"98.6"	"66.8"	"89.2"	"89.2"	"102.5"	"106.5"	"148.4"	"142.9"	"109.1"	"177.8"	"223.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01484"	"Ankyrin-2 OS=Homo sapiens OX=9606 GN=ANK2 PE=1 SV=4"	"1"	"5"	"6"	"2"	"3957"	"433.4"	"5.14"	"853.81"	"7.80"	"3"	"3"	"cell-cell signaling;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00023, Pf00531, Pf00791, Pf12796, Pf17809"	"287"	"ENSG00000145362"	"ANK2"	"hsa:287; Q01484; Q01485; Q08AC7; Q08AC8; Q7Z3L5"	""	"Interaction between L1 and Ankyrins; COPI-mediated anterograde transport"	"2"	"0"	"55.6"	"30.0"	"48.4"	"47.9"	"55.3"	"62.2"	"131.0"	"129.6"	"108.7"	"158.2"	"225.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15651"	"High mobility group nucleosome-binding domain-containing protein 3 OS=Homo sapiens OX=9606 GN=HMGN3 PE=1 SV=2"	"27"	"2"	"4"	"2"	"99"	"10.7"	"9.66"	"527.53"	"7.77"	"2"	"2"	"cell organization and biogenesis"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01101"	"9324"	"ENSG00000118418"	"HMGN3"	"B2RD37; hsa:9324; Q15651; Q5HYD3; Q7RTT0; Q969M5; Q9BZT7"	""	""	"0"	"0"	"123.9"	"78.5"	"107.4"	"140.4"	"117.5"	"138.9"	"551.8"	"462.9"	"353.3"	"542.5"	"671.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19387"	"DNA-directed RNA polymerase II subunit RPB3 OS=Homo sapiens OX=9606 GN=POLR2C PE=1 SV=2"	"13"	"2"	"3"	"2"	"275"	"31.4"	"4.92"	"435.06"	"7.77"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01000, Pf01193"	"5432"	"ENSG00000102978"	"POLR2C"	"hsa:5432; O15161; P19387"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Primary ovarian insufficiency"	"mRNA Splicing - Major Pathway; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"44"	"0"	"62.9"	"38.5"	"57.3"	"48.1"	"46.1"	"67.0"	"150.1"	"148.0"	"110.4"	"168.6"	"218.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P29966"	"Myristoylated alanine-rich C-kinase substrate OS=Homo sapiens OX=9606 GN=MARCKS PE=1 SV=4"	"8"	"2"	"4"	"2"	"332"	"31.5"	"4.45"	"957.20"	"7.76"	"2"	"2"	"cell organization and biogenesis;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02063"	"4082"	"ENSG00000277443"	"MARCKS"	"E1P560; hsa:4082; P29966; Q2LA83; Q5TDB7"	"Brain-derived neurotrophic factor (BDNF) signaling pathway"	"Acetylcholine regulates insulin secretion"	"2"	"0"	"508.8"	"296.7"	"391.4"	"316.2"	"376.9"	"378.2"	"516.4"	"448.1"	"347.9"	"575.0"	"881.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48729"	"Casein kinase I isoform alpha OS=Homo sapiens OX=9606 GN=CSNK1A1 PE=1 SV=2"	"6"	"2"	"6"	"2"	"337"	"38.9"	"9.57"	"810.71"	"7.75"	"2"	"2"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1452"	"ENSG00000113712"	"CSNK1A1"	"D3DQG0; D3DQG1; hsa:1452; P48729; Q4JJA0; Q5U046; Q5U047; Q6FGA2; Q71TU5; Q96HD2; Q9UDK3"	"Alzheimer's disease and miRNA effects; T cell receptor and co-stimulatory signaling; Complement system; Wnt signaling pathway; Wnt/beta-catenin signaling pathway in leukemia; Regulation of Wnt / B-catenin signaling by small molecule compounds; Chromosomal and microsatellite instability in colorectal cancer ; Hedgehog signaling pathway; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Influence of laminopathies on Wnt signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies; Pleural mesothelioma; Alzheimer's disease; DYRK1A involvement regarding cell proliferation in brain development"	"Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Activation of SMO; Disassembly of the destruction complex and recruitment of AXIN to the membrane; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; APC truncation mutants have impaired AXIN binding; AXIN missense mutants destabilize the destruction complex; Truncations of AMER1 destabilize the destruction complex; Maturation of nucleoprotein"	"32"	"0"	"45.7"	"26.1"	"40.9"	"45.2"	"41.4"	"40.2"	"263.7"	"232.3"	"158.6"	"269.4"	"333.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P43686"	"26S proteasome regulatory subunit 6B OS=Homo sapiens OX=9606 GN=PSMC4 PE=1 SV=2"	"3"	"1"	"4"	"1"	"418"	"47.3"	"5.21"	"675.12"	"7.73"	"1"	"1"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf16450, Pf17862"	"5704"	"ENSG00000013275; ENSG00000281221"	"PSMC4"	"hsa:5704; P43686; Q96FV5; Q9UBM3; Q9UEX3"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"Regulation of RAS by GAPs; Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"64"	"0"	"26.5"	"26.8"	"30.1"	"27.3"	"35.3"	"36.7"	"62.3"	"53.7"	"37.9"	"59.4"	"71.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKY7"	"Protein CDV3 homolog OS=Homo sapiens OX=9606 GN=CDV3 PE=1 SV=1"	"12"	"3"	"5"	"3"	"258"	"27.3"	"6.40"	"974.77"	"7.73"	"3"	"2"	""	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf15359"	"55573"	"ENSG00000091527"	"CDV3"	"B3KUC2; hsa:55573; Q96IP9; Q9UKY7"	""	""	"0"	"0"	"210.1"	"149.0"	"195.6"	"172.6"	"197.7"	"200.3"	"304.7"	"271.3"	"240.7"	"390.5"	"547.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q53EL6"	"Programmed cell death protein 4 OS=Homo sapiens OX=9606 GN=PDCD4 PE=1 SV=2"	"7"	"2"	"4"	"2"	"469"	"51.7"	"5.21"	"838.72"	"7.73"	"2"	"2"	"developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf02847"	"27250"	"ENSG00000150593"	"PDCD4"	"B2RCV4; B5ME91; hsa:27250; O15501; Q53EL6; Q5VZS6; Q6PJI5; Q8TAR5; Q99834"	"Translation inhibitors in chronically activated PDGFRA cells; A network map of Macrophage-stimulating protein (MSP) signaling; Interferon type I signaling pathways"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"4"	"0"	"36.0"	"29.0"	"36.9"	"32.9"	"31.5"	"41.7"	"78.8"	"65.2"	"51.1"	"63.8"	"73.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25398"	"40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3"	"14"	"3"	"6"	"3"	"132"	"14.5"	"7.21"	"1078.34"	"7.73"	"3"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01248"	"6206"	"ENSG00000112306"	"RPS12"	"hsa:6206; P25398; Q76M58"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"407.6"	"299.4"	"368.5"	"259.8"	"343.4"	"322.3"	"1053.7"	"999.6"	"744.3"	"932.0"	"1073.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63220"	"40S ribosomal protein S21 OS=Homo sapiens OX=9606 GN=RPS21 PE=1 SV=1"	"31"	"3"	"7"	"3"	"83"	"9.1"	"8.50"	"1357.80"	"7.68"	"3"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01249"	"6227"	"ENSG00000171858"	"RPS21"	"hsa:6227; P35265; P63220"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"452.1"	"352.7"	"390.9"	"357.2"	"374.7"	"355.7"	"1259.7"	"1156.0"	"791.3"	"1150.4"	"1417.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRX1"	"RNA-binding protein PNO1 OS=Homo sapiens OX=9606 GN=PNO1 PE=1 SV=1"	"12"	"2"	"4"	"2"	"252"	"27.9"	"9.73"	"821.14"	"7.64"	"2"	"2"	"other biological processes"	"cytosol;nucleus;other cell component"	""	""	"56902"	"ENSG00000115946"	"PNO1"	"A8K6Q0; hsa:56902; Q53G13; Q8WVB8; Q9NRX1"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"10.9"	"11.0"	"18.4"	"17.2"	"21.0"	"15.0"	"33.6"	"24.5"	"30.2"	"44.7"	"45.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43768"	"Alpha-endosulfine OS=Homo sapiens OX=9606 GN=ENSA PE=1 SV=1"	"29"	"3"	"6"	"3"	"121"	"13.4"	"7.24"	"931.64"	"7.61"	"3"	"3"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf04667"	"2029"	"ENSG00000143420"	"ENSA"	"A8K1Z9; E9PB69; hsa:2029; O43768; Q5T5H2; Q68D48; Q6FHW0; Q6IAM4; Q6NUL2; Q6VUC6; Q6VUC7; Q6VUC8; Q6VUC9; Q6VUD0; Q6VUD1; Q9NRZ0"	""	"MASTL Facilitates Mitotic Progression"	"1"	"0"	"315.6"	"202.3"	"283.6"	"262.9"	"268.2"	"300.3"	"479.0"	"422.4"	"336.5"	"546.6"	"792.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P5R6"	"60S ribosomal protein L22-like 1 OS=Homo sapiens OX=9606 GN=RPL22L1 PE=1 SV=2"	"25"	"2"	"3"	"2"	"122"	"14.6"	"9.38"	"285.07"	"7.61"	"1"	"2"	"protein metabolism;other metabolic processes"	"translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01776"	"200916"	"ENSG00000163584"	"RPL22L1"	"hsa:200916; Q32Q77; Q6P5R6"	""	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"13"	"0"	"69.9"	"54.9"	"68.0"	"70.6"	"58.8"	"85.0"	"426.9"	"411.6"	"294.7"	"531.4"	"852.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95104"	"SR-related and CTD-associated factor 4 OS=Homo sapiens OX=9606 GN=SCAF4 PE=1 SV=3"	"2"	"3"	"6"	"1"	"1147"	"125.8"	"9.55"	"947.61"	"7.60"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf04818"	"57466"	"ENSG00000156304"	"SCAF4"	"C9JLZ0; hsa:57466; O95104; Q0P5W8; Q6P1M5; Q8N3I8; Q9UFM1; Q9ULP8"	""	""	"0"	"2"	"255.7"	"157.7"	"192.3"	"165.3"	"203.8"	"204.5"	"502.0"	"480.6"	"354.3"	"583.0"	"767.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P84101"	"Small EDRK-rich factor 2 OS=Homo sapiens OX=9606 GN=SERF2 PE=1 SV=1"	"25"	"2"	"5"	"2"	"59"	"6.9"	"10.45"	"634.04"	"7.59"	"2"	"1"	"other biological processes"	"cytosol;nucleus"	""	"Pf04419"	"10169"	"ENSG00000140264"	"SERF2"	"A6NL45; B5MCG1; B9A026; hsa:10169; O75918; O88891; P84101; Q9BZH7"	""	""	"0"	"0"	"482.0"	"218.3"	"337.8"	"331.3"	"395.2"	"312.7"	"1243.2"	"1078.1"	"807.9"	"1276.0"	"2004.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NFH5"	"Nucleoporin NUP35 OS=Homo sapiens OX=9606 GN=NUP35 PE=1 SV=1"	"12"	"3"	"5"	"3"	"326"	"34.8"	"9.09"	"1216.86"	"7.56"	"3"	"2"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf05172"	"129401"	"ENSG00000163002"	"NUP35"	"B4DP57; B4DYB4; hsa:129401; Q4ZFZ9; Q53S95; Q8NFH5; Q8TDJ1"	""	"HCMV Early Events; ISG15 antiviral mechanism; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Transport of Mature mRNA derived from an Intron-Containing Transcript; HCMV Late Events; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; Postmitotic nuclear pore complex (NPC) reformation"	"29"	"0"	"134.1"	"68.6"	"98.2"	"95.7"	"104.3"	"113.2"	"293.4"	"269.9"	"194.9"	"310.5"	"346.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60866"	"40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1"	"27"	"3"	"6"	"3"	"119"	"13.4"	"9.94"	"1467.27"	"7.55"	"3"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00338"	"6224"	"ENSG00000008988"	"RPS20"	"B2R4F4; B4DW28; hsa:6224; P17075; P60866; Q5M8S9"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"354.3"	"179.3"	"293.6"	"249.2"	"313.5"	"268.0"	"958.7"	"858.5"	"576.9"	"905.5"	"1057.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00161"	"Synaptosomal-associated protein 23 OS=Homo sapiens OX=9606 GN=SNAP23 PE=1 SV=1"	"15"	"2"	"4"	"2"	"211"	"23.3"	"5.01"	"928.54"	"7.54"	"2"	"2"	"cell-cell signaling;cell organization and biogenesis;stress response;transport"	"plasma membrane;other membranes;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00835"	"8773"	"ENSG00000092531"	"SNAP23"	"hsa:8773; O00161; O00162; Q13602; Q6IAE3"	"Insulin signaling"	"RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; ER-Phagosome pathway; Translocation of SLC2A4 (GLUT4) to the plasma membrane; RAC3 GTPase cycle; RHOB GTPase cycle; RHOJ GTPase cycle; RHOF GTPase cycle; Neutrophil degranulation; trans-Golgi Network Vesicle Budding"	"13"	"0"	"72.3"	"42.2"	"72.1"	"67.0"	"66.9"	"67.9"	"96.6"	"96.5"	"68.8"	"129.2"	"141.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5SW79"	"Centrosomal protein of 170 kDa OS=Homo sapiens OX=9606 GN=CEP170 PE=1 SV=1"	"2"	"3"	"5"	"3"	"1584"	"175.2"	"7.11"	"573.77"	"7.54"	"2"	"3"	""	"cytosol;cytoskeleton;other cell component"	""	"Pf00498, Pf15308"	"9859"	"ENSG00000143702; ENSG00000276725"	"CEP170"	"hsa:9859; O75058; Q5SW77; Q5SW78; Q5SW79; Q7LGA9; Q86W31; Q9UQ08; Q9UQ09"	"Ciliary landscape"	""	"1"	"0"	"137.4"	"80.9"	"109.6"	"115.2"	"123.1"	"141.3"	"322.0"	"338.5"	"237.0"	"366.4"	"447.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P83881"	"60S ribosomal protein L36a OS=Homo sapiens OX=9606 GN=RPL36A PE=1 SV=2"	"27"	"3"	"5"	"3"	"106"	"12.4"	"10.58"	"588.51"	"7.49"	"2"	"3"	"protein metabolism;other metabolic processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;translational apparatus"	"other molecular function"	"Pf00935"	"6173"	"ENSG00000241343"	"RPL36A"	"hsa:6173; P09896; P10661; P83881; Q08ES5; Q5J9I6"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination"	"14"	"0"	"306.1"	"225.5"	"282.2"	"234.7"	"293.3"	"273.4"	"1037.1"	"937.9"	"656.3"	"1029.8"	"1156.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43663"	"Protein regulator of cytokinesis 1 OS=Homo sapiens OX=9606 GN=PRC1 PE=1 SV=2"	"4"	"3"	"5"	"1"	"620"	"71.6"	"6.68"	"579.34"	"7.47"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03999"	"9055"	"ENSG00000198901"	"PRC1"	"A6NC44; B4DLR1; H9KV59; hsa:9055; O43663; Q9BSB6"	""	"RHO GTPases activate CIT"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49588"	"Alanine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=AARS1 PE=1 SV=2"	"2"	"2"	"6"	"2"	"968"	"106.7"	"5.53"	"806.87"	"7.46"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;mitochondrion;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01411, Pf02272, Pf07973"	"16"	"ENSG00000090861"	"AARS1"	"A6NF14; B4DR45; hsa:16; P49588; Q53GV7; Q96FA0"	"IL-18 signaling pathway"	"Cytosolic tRNA aminoacylation"	"2"	"0"	"151.7"	"105.4"	"167.6"	"102.9"	"116.6"	"204.0"	"265.7"	"198.4"	"148.3"	"304.5"	"487.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BTL3"	"RNA guanine-N7 methyltransferase activating subunit OS=Homo sapiens OX=9606 GN=RAMAC PE=1 SV=1"	"19"	"2"	"4"	"2"	"118"	"14.4"	"8.94"	"944.02"	"7.45"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf15320"	"83640"	"ENSG00000169612"	"RAMAC"	"hsa:83640; Q2M1J8; Q9BTL3"	"15q25 copy number variation"	""	"1"	"0"	"124.1"	"91.4"	"113.8"	"139.3"	"136.5"	"157.1"	"297.9"	"299.4"	"221.7"	"316.0"	"336.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22570"	"NADPH:adrenodoxin oxidoreductase, mitochondrial OS=Homo sapiens OX=9606 GN=FDXR PE=1 SV=3"	"7"	"2"	"3"	"2"	"491"	"53.8"	"8.44"	"359.72"	"7.42"	"1"	"2"	"other metabolic processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf07992"	"2232"	"ENSG00000161513"	"FDXR"	"B4DDI7; B4DHX5; B4DQQ4; B4DX24; B7Z7G2; E7EQC1; hsa:2232; P22570; Q13716; Q4PJI0; Q9BU12"	"Iron-sulfur cluster biogenesis"	"Endogenous sterols; Pregnenolone biosynthesis; Defective CYP11A1 causes AICSR; Electron transport from NADPH to Ferredoxin"	"5"	"0"	"24.8"	"23.1"	"30.9"	"39.8"	"27.4"	"39.7"	"50.9"	"61.9"	"56.4"	"78.5"	"152.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99543"	"DnaJ homolog subfamily C member 2 OS=Homo sapiens OX=9606 GN=DNAJC2 PE=1 SV=4"	"4"	"2"	"4"	"2"	"621"	"72.0"	"8.70"	"771.26"	"7.41"	"2"	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"translation activity;other molecular function"	"Pf00226, Pf00249, Pf16717"	"27000"	"ENSG00000105821"	"DNAJC2"	"A4VCI0; hsa:27000; Q99543; Q9BVX1"	""	"Regulation of HSF1-mediated heat shock response"	"1"	"0"	"43.4"	"21.0"	"30.7"	"39.4"	"35.7"	"40.9"	"124.2"	"134.1"	"114.3"	"175.9"	"267.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61024"	"Cyclin-dependent kinases regulatory subunit 1 OS=Homo sapiens OX=9606 GN=CKS1B PE=1 SV=1"	"20"	"2"	"4"	"2"	"79"	"9.7"	"8.94"	"883.51"	"7.40"	"2"	"2"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01111"	"1163"	"ENSG00000173207"	"CKS1B"	"hsa:1163; P33551; P61024"	"Small cell lung cancer"	"SCF(Skp2)-mediated degradation of p27/p21; Cyclin D associated events in G1"	"3"	"0"	"257.6"	"150.7"	"198.3"	"203.4"	"179.4"	"222.0"	"393.1"	"427.2"	"335.2"	"487.1"	"643.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49916"	"DNA ligase 3 OS=Homo sapiens OX=9606 GN=LIG3 PE=1 SV=2"	"3"	"3"	"5"	"3"	"1009"	"112.8"	"9.01"	"598.24"	"7.38"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00645, Pf01068, Pf04675, Pf04679, Pf16759"	"3980"	"ENSG00000005156"	"LIG3"	"E5KLB5; E5KLB6; hsa:3980; P49916; Q16714; Q6NVK3"	"Base excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; 17q12 copy number variation syndrome"	"Gap-filling DNA repair synthesis and ligation in TC-NER; APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway; HDR through MMEJ (alt-NHEJ); Resolution of AP sites via the single-nucleotide replacement pathway; Gap-filling DNA repair synthesis and ligation in GG-NER"	"9"	"0"	"85.0"	"45.7"	"80.8"	"58.2"	"79.2"	"77.7"	"203.0"	"198.1"	"130.3"	"237.8"	"389.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NS69"	"Mitochondrial import receptor subunit TOM22 homolog OS=Homo sapiens OX=9606 GN=TOMM22 PE=1 SV=3"	"25"	"2"	"3"	"2"	"142"	"15.5"	"4.34"	"358.92"	"7.38"	"1"	"2"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity"	"Pf04281"	"56993"	"ENSG00000100216"	"TOMM22"	"hsa:56993; Q9NS69"	""	"PINK1-PRKN Mediated Mitophagy; Mitochondrial protein import"	"2"	"0"	"61.0"	"42.8"	"74.2"	"49.2"	"51.9"	"61.9"	"85.5"	"84.3"	"68.4"	"116.3"	"128.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P15927"	"Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1"	"10"	"2"	"2"	"2"	"270"	"29.2"	"6.15"	""	"7.32"	""	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf08784"	"6118"	"ENSG00000117748"	"RPA2"	"hsa:6118; P15927; Q52II0; Q5TEI9; Q5TEJ5"	"miRNA regulation of DNA damage response; Retinoblastoma gene in cancer; G1 to S cell cycle control; DNA replication; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair; DNA damage response"	"Fanconi Anemia Pathway; Regulation of HSF1-mediated heat shock response; Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Meiotic recombination; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; HSF1 activation; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Removal of the Flap Intermediate; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"38"	"0"	"129.5"	"81.6"	"120.5"	"92.8"	"93.6"	"121.4"	"182.8"	"154.7"	"110.9"	"165.0"	"234.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00273"	"DNA fragmentation factor subunit alpha OS=Homo sapiens OX=9606 GN=DFFA PE=1 SV=1"	"15"	"4"	"6"	"4"	"331"	"36.5"	"4.79"	"1468.22"	"7.29"	"4"	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02017, Pf09033"	"1676"	"ENSG00000160049"	"DFFA"	"hsa:1676; O00273; Q5T6G5; Q5T6G6; Q96I97; Q9Y6C6"	"Apoptosis; Fas ligand pathway and stress induction of heat shock proteins; Acute viral myocarditis"	"Apoptosis induced DNA fragmentation"	"4"	"0"	"144.2"	"75.5"	"95.1"	"141.9"	"104.3"	"181.4"	"236.2"	"227.4"	"168.4"	"248.5"	"376.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20248"	"Cyclin-A2 OS=Homo sapiens OX=9606 GN=CCNA2 PE=1 SV=2"	"6"	"2"	"4"	"2"	"432"	"48.5"	"6.54"	"808.77"	"7.28"	"2"	"2"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00134, Pf02984, Pf16500"	"890"	"ENSG00000145386"	"CCNA2"	"A8K7B6; hsa:890; P20248; Q2M3U6; Q4W5P4; Q6LER8"	"AMP-activated protein kinase signaling; Cell cycle; Retinoblastoma gene in cancer; IL-18 signaling pathway"	"TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; Regulation of TP53 Degradation; SCF(Skp2)-mediated degradation of p27/p21; Regulation of TP53 Activity through Phosphorylation; G2 Phase; Telomere Extension By Telomerase; Regulation of APC/C activators between G1/S and early anaphase; Senescence-Associated Secretory Phenotype (SASP); Processing of DNA double-strand break ends; DNA Damage/Telomere Stress Induced Senescence; p53-Dependent G1 DNA Damage Response; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1; Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes"	"24"	"0"	"69.5"	"36.2"	"50.0"	"52.2"	"61.1"	"60.1"	"168.9"	"164.7"	"138.9"	"200.1"	"321.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13619"	"Cullin-4A OS=Homo sapiens OX=9606 GN=CUL4A PE=1 SV=3"	"4"	"3"	"6"	"1"	"759"	"87.6"	"8.13"	"1123.89"	"7.27"	"3"	"3"	"cell cycle OR cell proliferation;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00888, Pf10557"	"8451"	"ENSG00000139842"	"CUL4A"	"A2A2W2; hsa:8451; O75834; Q13619; Q589T6; Q5TC62; Q6UP08; Q9UP17"	"Hippo-Merlin signaling dysregulation; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; Dual Incision in GG-NER; Neddylation; Formation of TC-NER Pre-Incision Complex; DNA Damage Recognition in GG-NER"	"13"	"0"	"22.1"	"14.1"	"17.5"	"14.3"	"19.3"	"20.9"	"33.5"	"34.0"	"25.0"	"39.9"	"70.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6G9"	"Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens OX=9606 GN=DYNC1LI1 PE=1 SV=3"	"7"	"3"	"6"	"3"	"523"	"56.5"	"6.42"	"746.38"	"7.23"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf05783"	"51143"	"ENSG00000144635"	"DYNC1LI1"	"A2RRG7; hsa:51143; Q53HC8; Q53HK7; Q9Y6G9"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein"	"Separation of Sister Chromatids; MHC class II antigen presentation; Neutrophil degranulation; COPI-independent Golgi-to-ER retrograde traffic; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; HCMV Early Events; Aggrephagy; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"15"	"0"	"55.4"	"47.3"	"47.6"	"46.0"	"56.2"	"55.1"	"97.8"	"90.4"	"77.2"	"119.6"	"152.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q29RF7"	"Sister chromatid cohesion protein PDS5 homolog A OS=Homo sapiens OX=9606 GN=PDS5A PE=1 SV=1"	"3"	"3"	"5"	"2"	"1337"	"150.7"	"7.91"	"587.27"	"7.23"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	""	"Pf20168"	"23244"	"ENSG00000121892"	"PDS5A"	"hsa:23244; Q29RF7; Q2TTR5; Q68DF7; Q8N7J4; Q8NG14; Q9Y4D4"	"Cohesin complex - Cornelia de Lange syndrome; 10q22q23 copy number variation"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"6"	"0"	"74.6"	"56.8"	"65.0"	"61.0"	"59.5"	"66.9"	"160.9"	"158.2"	"117.3"	"186.3"	"323.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00151"	"PDZ and LIM domain protein 1 OS=Homo sapiens OX=9606 GN=PDLIM1 PE=1 SV=4"	"12"	"2"	"3"	"2"	"329"	"36.0"	"7.02"	"338.11"	"7.22"	"1"	"2"	"cell organization and biogenesis;stress response;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412, Pf00595, Pf15936"	"9124"	"ENSG00000107438"	"PDLIM1"	"B2RBS6; hsa:9124; O00151; Q5VZH5; Q9BPZ9"	""	""	"0"	"0"	"72.7"	"49.9"	"65.3"	"59.7"	"55.8"	"69.0"	"101.1"	"102.6"	"77.8"	"117.2"	"182.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H4G0"	"Band 4.1-like protein 1 OS=Homo sapiens OX=9606 GN=EPB41L1 PE=1 SV=2"	"4"	"3"	"5"	"3"	"881"	"98.4"	"5.62"	"1175.89"	"7.22"	"3"	"2"	"cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;cytoskeleton"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf04382, Pf05902, Pf08736, Pf09379, Pf09380"	"2036"	"ENSG00000088367"	"EPB41L1"	"hsa:2036; O15046; Q4VXM6; Q4VXM7; Q4VXM8; Q4VXN4; Q6ZT61; Q8IUU7; Q96CV5; Q96L65; Q9H4G0"	"Splicing factor NOVA regulated synaptic proteins"	"Trafficking of AMPA receptors; Neurexins and neuroligins; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea"	"5"	"0"	"29.4"	"14.5"	"18.1"	"23.7"	"21.4"	"20.3"	"57.2"	"84.3"	"130.5"	"303.4"	"453.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNZ2"	"NSFL1 cofactor p47 OS=Homo sapiens OX=9606 GN=NSFL1C PE=1 SV=2"	"8"	"2"	"3"	"2"	"370"	"40.5"	"5.10"	"313.68"	"7.22"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00789, Pf08059, Pf14555"	"55968"	"ENSG00000088833"	"NSFL1C"	"A2A2L1; B2RD74; hsa:55968; Q5JXA4; Q5JXA5; Q7Z533; Q9H102; Q9NVL9; Q9UI06; Q9UNZ2"	"Alstrom syndrome"	"RHOH GTPase cycle"	"2"	"0"	"26.0"	"15.1"	"29.2"	"30.9"	"33.3"	"26.2"	"55.9"	"47.3"	"41.6"	"72.7"	"74.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23919"	"Thymidylate kinase OS=Homo sapiens OX=9606 GN=DTYMK PE=1 SV=4"	"9"	"3"	"5"	"3"	"212"	"23.8"	"8.27"	"495.56"	"7.21"	"2"	"3"	"other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf02223"	"1841"	"ENSG00000168393"	"DTYMK"	"B7ZW70; hsa:1841; P23919; Q6FGX1; Q9BUX4"	"Pyrimidine metabolism; 2q37 copy number variation syndrome"	"Interconversion of nucleotide di- and triphosphates"	"3"	"0"	"109.1"	"66.6"	"94.3"	"103.2"	"86.9"	"108.8"	"216.3"	"218.7"	"178.3"	"249.8"	"390.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75717"	"WD repeat and HMG-box DNA-binding protein 1 OS=Homo sapiens OX=9606 GN=WDHD1 PE=1 SV=1"	"2"	"2"	"4"	"2"	"1129"	"125.9"	"5.62"	"953.35"	"7.20"	"2"	"2"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400, Pf12341, Pf12894"	"11169"	"ENSG00000198554"	"WDHD1"	"C9JW18; F6W0U7; hsa:11169; O75717"	"Mesodermal commitment pathway"	""	"1"	"0"	"25.7"	"16.7"	"28.5"	"26.1"	"31.5"	"33.3"	"73.7"	"60.9"	"51.4"	"67.2"	"100.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75718"	"Cartilage-associated protein OS=Homo sapiens OX=9606 GN=CRTAP PE=1 SV=1"	"6"	"3"	"6"	"3"	"401"	"46.5"	"5.73"	"846.03"	"7.19"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;ER/Golgi;other cell component"	""	""	"10491"	"ENSG00000170275"	"CRTAP"	"B2RBL6; hsa:10491; O75718"	"Type I collagen synthesis in the context of osteogenesis imperfecta"	"Collagen biosynthesis and modifying enzymes"	"2"	"0"	"338.9"	"241.7"	"362.7"	"326.0"	"357.9"	"424.8"	"615.9"	"604.6"	"445.9"	"688.2"	"941.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WUD4"	"Coiled-coil domain-containing protein 12 OS=Homo sapiens OX=9606 GN=CCDC12 PE=1 SV=1"	"18"	"2"	"3"	"2"	"166"	"19.2"	"7.34"	"240.71"	"7.18"	"1"	"2"	""	"nucleus"	""	"Pf08315"	"151903"	"ENSG00000160799"	"CCDC12"	"hsa:151903; Q8N8I4; Q8WUD4"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"112.3"	"78.9"	"90.2"	"82.9"	"92.9"	"133.8"	"271.2"	"269.5"	"231.7"	"325.9"	"388.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NUU7"	"ATP-dependent RNA helicase DDX19A OS=Homo sapiens OX=9606 GN=DDX19A PE=1 SV=1"	"6"	"3"	"5"	"3"	"478"	"53.9"	"6.58"	"589.81"	"7.17"	"2"	"3"	"other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"55308"	"ENSG00000168872"	"DDX19A"	"B2RPL0; B4DRZ7; hsa:55308; Q53FM0; Q9NUU7"	""	""	"0"	"0"	"40.4"	"27.7"	"41.3"	"45.1"	"54.4"	"43.1"	"147.1"	"132.1"	"110.3"	"160.1"	"227.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50579"	"Methionine aminopeptidase 2 OS=Homo sapiens OX=9606 GN=METAP2 PE=1 SV=1"	"4"	"2"	"4"	"2"	"478"	"52.9"	"5.82"	"876.75"	"7.16"	"2"	"2"	"protein metabolism;other metabolic processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00557"	"10988"	"ENSG00000111142"	"METAP2"	"B2RDI8; B4DUX5; G3XA91; hsa:10988; P50579; Q8NB11"	""	"Inactivation, recovery and regulation of the phototransduction cascade"	"1"	"0"	"9.0"	"0.0"	"9.5"	"7.2"	"11.3"	"6.4"	"21.5"	"19.9"	"13.9"	"30.2"	"53.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P28340"	"DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2"	"2"	"2"	"4"	"2"	"1107"	"123.6"	"7.03"	"766.20"	"7.11"	"2"	"2"	"DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00136, Pf03104, Pf14260"	"5424"	"ENSG00000062822"	"POLD1"	"hsa:5424; P28340; Q8NER3; Q96H98"	"Homologous recombination; Pyrimidine metabolism; DNA replication; Base excision repair; Nucleotide excision repair; DNA repair pathways, full network; Progeria-associated lipodystrophy; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Removal of the Flap Intermediate; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta); Cytosolic iron-sulfur cluster assembly; Polymerase switching on the C-strand of the telomere; Polymerase switching"	"27"	"0"	"65.6"	"38.3"	"60.6"	"73.1"	"65.1"	"89.5"	"135.6"	"187.2"	"147.6"	"188.1"	"243.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13425"	"Beta-2-syntrophin OS=Homo sapiens OX=9606 GN=SNTB2 PE=1 SV=1"	"4"	"2"	"6"	"2"	"540"	"57.9"	"8.82"	"957.62"	"7.07"	"2"	"2"	""	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00595, Pf18012"	"6645"	"ENSG00000168807"	"SNTB2"	"hsa:6645; Q13425; Q9BY09"	""	""	"0"	"0"	"81.0"	"49.6"	"48.0"	"53.9"	"62.2"	"71.8"	"135.0"	"138.4"	"100.9"	"147.0"	"149.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05386"	"60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1"	"19"	"2"	"5"	"2"	"114"	"11.5"	"4.32"	"1037.83"	"7.02"	"2"	"2"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00428"	"6176"	"ENSG00000137818"	"RPLP1"	"A6NIB2; hsa:6176; P05386"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"311.2"	"226.2"	"231.4"	"202.1"	"225.9"	"258.4"	"954.0"	"880.8"	"579.9"	"1000.3"	"1233.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42771"	"Cyclin-dependent kinase inhibitor 2A OS=Homo sapiens OX=9606 GN=CDKN2A PE=1 SV=2"	"19"	"2"	"4"	"2"	"156"	"16.5"	"5.81"	"733.73"	"6.99"	"2"	"2"	"cell cycle OR cell proliferation;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	""	"1029"	"ENSG00000147889"	"CDKN2A"	"A5X2G7; D3DRK1; G3XAG3; hsa:1029; O95440; P42771; Q15191; Q5VVJ5; Q96B52; Q9NP05"	"TP53 network; Cell cycle; Glioblastoma signaling pathways; Apoptosis; Bladder cancer; Vitamin D receptor pathway; Tumor suppressor activity of SMARCB1; Non-small cell lung cancer; Pancreatic adenocarcinoma pathway; G1 to S cell cycle control; Fragile X syndrome; Gastrin signaling pathway; Head and neck squamous cell carcinoma; Melanoma; Pleural mesothelioma; TROP2 regulatory signaling"	"Cyclin D associated events in G1; Oxidative Stress Induced Senescence; Oncogene Induced Senescence; Senescence-Associated Secretory Phenotype (SASP); Transcriptional Regulation by VENTX; Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4; Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6; Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4; Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6"	"25"	"0"	"68.3"	"41.1"	"64.6"	"62.1"	"69.1"	"72.1"	"112.8"	"122.7"	"80.5"	"137.2"	"167.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52435"	"DNA-directed RNA polymerase II subunit RPB11-a OS=Homo sapiens OX=9606 GN=POLR2J PE=1 SV=1"	"26"	"2"	"3"	"2"	"117"	"13.3"	"5.86"	"426.12"	"6.99"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13656"	"5439"	"ENSG00000005075"	"POLR2J"	"A5D6V8; hsa:5439; O43375; P52435"	"Pyrimidine metabolism; Eukaryotic transcription initiation"	"mRNA Splicing - Major Pathway; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"43"	"0"	"124.0"	"82.3"	"101.9"	"63.6"	"101.1"	"82.9"	"124.3"	"123.8"	"94.7"	"149.1"	"211.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P29590"	"Protein PML OS=Homo sapiens OX=9606 GN=PML PE=1 SV=3"	"4"	"2"	"3"	"2"	"882"	"97.5"	"6.21"	"513.98"	"6.98"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00643, Pf12126"	"5371"	"ENSG00000140464"	"PML"	"E9PBR7; hsa:5371; P29590; P29591; P29592; P29593; Q00755; Q15959; Q59FP9; Q8WUA0; Q96S41; Q9BPW2; Q9BWP7; Q9BZX6; Q9BZX7; Q9BZX8; Q9BZX9; Q9BZY0; Q9BZY2; Q9BZY3"	"miRNA regulation of DNA damage response; Wnt/beta-catenin signaling pathway in leukemia; p53 transcriptional gene network; DNA damage response"	"HCMV Early Events; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Interferon gamma signaling; Regulation of TP53 Activity through Acetylation; Regulation of PTEN localization; Regulation of RUNX1 Expression and Activity"	"11"	"0"	"71.6"	"63.6"	"74.8"	"96.3"	"80.1"	"100.8"	"158.3"	"129.5"	"112.0"	"149.7"	"186.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75152"	"Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3"	"3"	"3"	"5"	"2"	"810"	"89.1"	"8.37"	"629.04"	"6.98"	"2"	"3"	"other metabolic processes;transport"	"nucleus"	"other molecular function"	"Pf15663"	"9877"	"ENSG00000058673"	"ZC3H11A"	"hsa:9877; O75152; Q6AHY4; Q6AHY9; Q6AW79; Q6AWA1; Q6PJK4; Q86XZ7"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"3"	"0"	"62.5"	"36.6"	"57.0"	"51.6"	"47.4"	"56.8"	"104.7"	"85.2"	"72.8"	"123.5"	"156.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96QC0"	"Serine/threonine-protein phosphatase 1 regulatory subunit 10 OS=Homo sapiens OX=9606 GN=PPP1R10 PE=1 SV=1"	"3"	"3"	"5"	"3"	"940"	"99.0"	"9.17"	"496.49"	"6.96"	"2"	"3"	"transport;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00642, Pf08711"	"5514"	"ENSG00000204569; ENSG00000206489; ENSG00000227804; ENSG00000230995; ENSG00000231737; ENSG00000235291; ENSG00000238104"	"PPP1R10"	"hsa:5514; O00405; Q96QC0"	""	""	"0"	"0"	"241.2"	"131.7"	"191.6"	"185.0"	"220.4"	"234.2"	"540.5"	"481.5"	"343.7"	"594.8"	"815.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NE71"	"ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2"	"3"	"2"	"4"	"2"	"845"	"95.9"	"6.80"	"985.97"	"6.95"	"2"	"2"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00005, Pf12848"	"23"	"ENSG00000204574; ENSG00000206490; ENSG00000225989; ENSG00000231129; ENSG00000232169; ENSG00000236149; ENSG00000236342"	"ABCF1"	"A2BF75; hsa:23; O14897; Q69YP6; Q8NE71"	"IL-18 signaling pathway"	"ABC-family proteins mediated transport"	"2"	"0"	"70.4"	"41.1"	"69.8"	"69.9"	"78.3"	"69.2"	"188.2"	"178.9"	"113.5"	"214.7"	"403.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NX24"	"H/ACA ribonucleoprotein complex subunit 2 OS=Homo sapiens OX=9606 GN=NHP2 PE=1 SV=1"	"12"	"1"	"3"	"1"	"153"	"17.2"	"8.22"	"601.92"	"6.95"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf01248"	"55651"	"ENSG00000145912"	"NHP2"	"A6NKY8; hsa:55651; Q9NX24; Q9P095"	""	"rRNA modification in the nucleus and cytosol; Telomere Extension By Telomerase"	"2"	"0"	"20.3"	"10.8"	"20.0"	"23.9"	"20.8"	"23.5"	"61.8"	"72.7"	"62.4"	"99.9"	"131.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15435"	"Protein phosphatase 1 regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PPP1R7 PE=1 SV=1"	"8"	"2"	"4"	"2"	"360"	"41.5"	"4.91"	"806.93"	"6.94"	"2"	"2"	"other biological processes"	"other cell component"	"enzyme regulator activity"	"Pf14580"	"5510"	"ENSG00000115685"	"PPP1R7"	"B4DFD4; B5MCY6; hsa:5510; Q15435; Q9UQE5; Q9UQE6; Q9Y6K4"	"2q37 copy number variation syndrome"	""	"1"	"0"	"21.0"	"20.9"	"19.8"	"21.1"	"22.8"	"18.6"	"33.8"	"30.1"	"33.7"	"88.6"	"132.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86SX6"	"Glutaredoxin-related protein 5, mitochondrial OS=Homo sapiens OX=9606 GN=GLRX5 PE=1 SV=2"	"11"	"2"	"5"	"2"	"157"	"16.6"	"6.79"	"512.44"	"6.94"	"1"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00462"	"51218"	"ENSG00000182512"	"GLRX5"	"hsa:51218; Q0X088; Q3YML0; Q86SX6; Q86WY3; Q8IZ54"	"Iron-sulfur cluster biogenesis"	"Mitochondrial iron-sulfur cluster biogenesis"	"2"	"0"	"151.8"	"89.2"	"93.5"	"119.0"	"105.5"	"123.1"	"160.8"	"155.1"	"128.5"	"173.3"	"255.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96N67"	"Dedicator of cytokinesis protein 7 OS=Homo sapiens OX=9606 GN=DOCK7 PE=1 SV=4"	"1"	"2"	"4"	"2"	"2140"	"242.4"	"6.80"	"771.19"	"6.90"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"other cell component"	"enzyme regulator activity;other molecular function"	"Pf06920, Pf11878, Pf14429, Pf20421, Pf20422"	"85440"	"ENSG00000116641"	"DOCK7"	"hsa:85440; Q00M63; Q2PPY7; Q45RE8; Q45RE9; Q5T1B9; Q5T1C0; Q6ZV32; Q8TB82; Q96N67; Q96NG6; Q96NI0; Q9C092"	""	"RAC1 GTPase cycle; CDC42 GTPase cycle; Factors involved in megakaryocyte development and platelet production; MET activates RAP1 and RAC1"	"4"	"0"	"61.8"	"36.7"	"60.5"	"62.2"	"67.1"	"62.1"	"126.0"	"140.1"	"99.9"	"137.0"	"186.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94813"	"Slit homolog 2 protein OS=Homo sapiens OX=9606 GN=SLIT2 PE=1 SV=1"	"3"	"4"	"6"	"4"	"1529"	"169.8"	"7.06"	"1254.43"	"6.88"	"4"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;other membranes;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00008, Pf01462, Pf01463, Pf02210, Pf12661, Pf13855"	"9353"	"ENSG00000145147"	"SLIT2"	"A0A0A6YYB8; B7ZLR5; hsa:9353; O94813; O95710; Q17RU3; Q9Y5Q7"	"Spinal cord injury; Robo4 and VEGF signaling pathways crosstalk; Genes controlling nephrogenesis; GDNF/RET signaling axis; Development of ureteric collection system"	"Regulation of expression of SLITs and ROBOs; Netrin-1 signaling; Inactivation of CDC42 and RAC1; Activation of RAC1; Regulation of commissural axon pathfinding by SLIT and ROBO; Role of ABL in ROBO-SLIT signaling; SLIT2:ROBO1 increases RHOA activity"	"13"	"0"	"101.8"	"48.0"	"68.2"	"60.5"	"73.3"	"77.5"	"215.4"	"214.5"	"185.8"	"293.3"	"434.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01780"	"Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2"	"4"	"2"	"3"	"2"	"885"	"100.8"	"8.46"	"330.14"	"6.86"	"1"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00570, Pf01612, Pf08066"	"5394"	"ENSG00000171824"	"EXOSC10"	"B1AKQ0; B1AKQ1; hsa:5394; Q01780; Q15158"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"13.4"	"9.1"	"9.0"	"16.7"	"17.8"	"20.3"	"40.0"	"30.3"	"20.9"	"44.5"	"66.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96I51"	"RCC1-like G exchanging factor-like protein OS=Homo sapiens OX=9606 GN=RCC1L PE=1 SV=2"	"7"	"2"	"3"	"2"	"464"	"50.0"	"8.40"	"296.80"	"6.84"	"1"	"2"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"9.5"	"6.2"	"9.1"	"7.5"	"13.4"	"10.4"	"18.6"	"23.2"	"17.9"	"21.6"	"36.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61956"	"Small ubiquitin-related modifier 2 OS=Homo sapiens OX=9606 GN=SUMO2 PE=1 SV=3"	"23"	"2"	"4"	"2"	"95"	"10.9"	"5.50"	"787.63"	"6.82"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf11976"	"6613"	"ENSG00000188612"	"SUMO2"	"B2R4I2; hsa:6613; P55855; P61956; Q32Q42; Q6IPZ6; Q96HK1"	"TAR syndrome"	"Formation of Incision Complex in GG-NER; SUMOylation of DNA damage response and repair proteins; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; SUMOylation of transcription cofactors; SUMOylation of intracellular receptors; Processing of DNA double-strand break ends; Vitamin D (calciferol) metabolism; SUMOylation of transcription factors; SUMO is conjugated to E1 (UBA2:SAE1); SUMO is transferred from E1 to E2 (UBE2I, UBC9); SUMO is proteolytically processed"	"15"	"0"	"140.0"	"87.4"	"133.9"	"95.8"	"115.4"	"128.5"	"166.1"	"136.9"	"106.0"	"184.0"	"292.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16836"	"Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=HADH PE=1 SV=3"	"11"	"3"	"6"	"3"	"314"	"34.3"	"8.85"	"1302.50"	"6.81"	"3"	"1"	"other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00725, Pf02737"	"3033"	"ENSG00000138796"	"HADH"	"hsa:3033; J3KQ17; O00324; O00397; O00753; Q16836; Q4W5B4"	"Fatty acid beta-oxidation; Fatty acid biosynthesis; Mitochondrial long chain fatty acid beta-oxidation; Amino acid metabolism; IL-18 signaling pathway; Mitochondrial fatty acid oxidation disorders"	"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of butanoyl-CoA to acetyl-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA"	"11"	"0"	"75.8"	"40.3"	"74.0"	"81.7"	"71.2"	"95.7"	"266.9"	"246.8"	"166.1"	"323.2"	"596.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53041"	"Serine/threonine-protein phosphatase 5 OS=Homo sapiens OX=9606 GN=PPP5C PE=1 SV=1"	"5"	"2"	"4"	"2"	"499"	"56.8"	"6.28"	"705.44"	"6.79"	"2"	"2"	"cell cycle OR cell proliferation;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00149, Pf00515, Pf08321"	"5536"	"ENSG00000011485"	"PPP5C"	"hsa:5536; P53041; Q16722; Q53XV2"	"MAPK signaling pathway; ATM signaling in development and disease"	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Negative regulation of MAPK pathway; ESR-mediated signaling"	"5"	"0"	"34.9"	"30.3"	"31.9"	"46.6"	"45.8"	"58.3"	"87.9"	"94.8"	"91.2"	"173.8"	"309.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q68CQ4"	"Digestive organ expansion factor homolog OS=Homo sapiens OX=9606 GN=DIEXF PE=1 SV=2"	"3"	"3"	"5"	"3"	"756"	"87.0"	"5.88"	"543.66"	"6.75"	"2"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf06862"	"27042"	"ENSG00000117597"	"UTP25"	"hsa:27042; O75992; Q4VY00; Q63HL9; Q68CQ4"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63165"	"Small ubiquitin-related modifier 1 OS=Homo sapiens OX=9606 GN=SUMO1 PE=1 SV=1"	"20"	"2"	"3"	"2"	"101"	"11.6"	"5.52"	"455.66"	"6.75"	"1"	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf11976"	"7341"	"ENSG00000116030"	"SUMO1"	"A8MUS8; B2R4I5; hsa:7341; P55856; P63165; Q6FGG0; Q6NZ62; Q93068"	"Androgen receptor signaling pathway; TP53 network; Exercise-induced circadian regulation"	"SUMOylation of DNA replication proteins; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; SUMOylation of intracellular receptors; Regulation of IFNG signaling; SUMOylation of transcription factors; Postmitotic nuclear pore complex (NPC) reformation; Formation of Incision Complex in GG-NER; Negative regulation of activity of TFAP2 (AP-2) family transcription factors; Maturation of nucleoprotein; SUMOylation of immune response proteins; SUMOylation of nuclear envelope proteins; Maturation of nucleoprotein; SUMO is conjugated to E1 (UBA2:SAE1); SUMO is transferred from E1 to E2 (UBE2I, UBC9); SUMO is proteolytically processed"	"25"	"0"	"327.1"	"181.0"	"268.7"	"260.8"	"237.3"	"269.2"	"749.5"	"721.3"	"562.8"	"749.2"	"989.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13674"	"Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2"	"7"	"4"	"6"	"4"	"534"	"61.0"	"6.01"	"1411.24"	"6.75"	"4"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf08336, Pf13640"	"5033"	"ENSG00000122884"	"P4HA1"	"C9JL12; hsa:5033; P13674; Q15082; Q15083; Q5VSQ5"	"Type I collagen synthesis in the context of osteogenesis imperfecta"	"Collagen biosynthesis and modifying enzymes"	"2"	"0"	"110.2"	"70.3"	"88.7"	"108.9"	"81.7"	"119.5"	"195.3"	"203.6"	"155.4"	"198.5"	"312.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NQW7"	"Xaa-Pro aminopeptidase 1 OS=Homo sapiens OX=9606 GN=XPNPEP1 PE=1 SV=3"	"5"	"2"	"4"	"2"	"623"	"69.9"	"5.67"	"704.69"	"6.73"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00557, Pf01321, Pf16188, Pf16189"	"7511"	"ENSG00000108039"	"XPNPEP1"	"A8K071; G5E9Y2; G8JLB2; hsa:7511; O15250; Q53EX6; Q8N3Q0; Q96D23; Q9NQW7"	""	""	"0"	"0"	"45.0"	"31.4"	"48.6"	"61.0"	"44.2"	"80.5"	"146.7"	"151.6"	"98.0"	"126.9"	"174.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82933"	"28S ribosomal protein S9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS9 PE=1 SV=2"	"3"	"1"	"4"	"1"	"396"	"45.8"	"9.51"	"739.03"	"6.73"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf00380"	"64965"	"ENSG00000135972"	"MRPS9"	"hsa:64965; P82933; Q6PG40"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"63.3"	"35.7"	"46.7"	"51.1"	"39.0"	"53.9"	"111.0"	"93.2"	"79.9"	"123.1"	"135.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06730"	"Eukaryotic translation initiation factor 4E OS=Homo sapiens OX=9606 GN=EIF4E PE=1 SV=2"	"10"	"3"	"5"	"3"	"217"	"25.1"	"6.15"	"555.04"	"6.71"	"2"	"3"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01652"	"1977"	"ENSG00000151247"	"EIF4E"	"B7Z6V1; D6RCQ6; hsa:1977; P06730; Q96E95"	"Translation factors; Leptin signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Interleukin-1 (IL-1) structural pathway; Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4); Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; 4-hydroxytamoxifen, dexamethasone, and retinoic acids regulation of p27 expression; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Prader-Willi and Angelman syndrome; PI3K-Akt signaling pathway; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Head and neck squamous cell carcinoma; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; Host-pathogen interaction of human coronaviruses - MAPK signaling; Hypertrophy model; Interferon type I signaling pathways"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Deadenylation of mRNA; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; mTORC1-mediated signalling"	"31"	"0"	"301.3"	"230.3"	"335.6"	"245.6"	"312.4"	"277.5"	"415.7"	"410.8"	"305.5"	"602.5"	"1119.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y657"	"Spindlin-1 OS=Homo sapiens OX=9606 GN=SPIN1 PE=1 SV=3"	"10"	"2"	"4"	"2"	"262"	"29.6"	"6.96"	"753.38"	"6.66"	"2"	"2"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus"	"other molecular function"	"Pf02513"	"10927"	"ENSG00000106723"	"SPIN1"	"A8K0X6; B3KRQ4; hsa:10927; Q7KZJ8; Q9GZT2; Q9H0N7; Q9Y657"	""	""	"0"	"0"	"88.4"	"71.9"	"86.8"	"81.6"	"84.6"	"90.9"	"181.5"	"178.8"	"142.4"	"218.6"	"263.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P24941"	"Cyclin-dependent kinase 2 OS=Homo sapiens OX=9606 GN=CDK2 PE=1 SV=2"	"7"	"2"	"4"	"1"	"298"	"33.9"	"8.68"	"722.25"	"6.65"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1017"	"ENSG00000123374"	"CDK2"	"A8K7C6; hsa:1017; O75100; P24941"	"miRNA regulation of DNA damage response; Cell cycle; Thyroid stimulating hormone (TSH) signaling pathway; Glioblastoma signaling pathways; Oncostatin M signaling pathway; Spinal cord injury; Retinoblastoma gene in cancer; Aryl hydrocarbon receptor pathway; Vitamin D receptor pathway; PI3K-Akt signaling pathway; G1 to S cell cycle control; Measles virus infection; Small cell lung cancer; DNA replication; p53 transcriptional gene network; Pleural mesothelioma; Sphingolipid metabolism in senescence; Urotensin-II-mediated signaling pathway; ID signaling pathway; TROP2 regulatory signaling; DNA damage response"	"Senescence-Associated Secretory Phenotype (SASP); Meiotic recombination; DNA Damage/Telomere Stress Induced Senescence; Transcriptional regulation of granulopoiesis; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; SCF(Skp2)-mediated degradation of p27/p21; TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest; Regulation of TP53 Degradation; Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; G2 Phase; Cyclin D associated events in G1; Defective binding of RB1 mutants to E2F1,(E2F2, E2F3); Telomere Extension By Telomerase; Regulation of APC/C activators between G1/S and early anaphase; Factors involved in megakaryocyte development and platelet production; Processing of DNA double-strand break ends; Cyclin A/B1/B2 associated events during G2/M transition; G0 and Early G1; Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes; p53-Dependent G1 DNA Damage Response; PTK6 Regulates Cell Cycle"	"47"	"0"	"29.3"	"13.5"	"23.3"	"24.6"	"24.4"	"23.3"	"53.2"	"35.3"	"35.5"	"66.3"	"110.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P36959"	"GMP reductase 1 OS=Homo sapiens OX=9606 GN=GMPR PE=1 SV=1"	"9"	"2"	"2"	"1"	"345"	"37.4"	"7.06"	""	"6.65"	""	"2"	"other metabolic processes;stress response"	"cytosol;other cell component"	"other molecular function"	"Pf00478"	"2766"	"ENSG00000137198"	"GMPR"	"hsa:2766; P36959; Q96HQ6"	""	"Purine salvage"	"1"	"0"	"0.0"	"0.0"	"3.8"	"3.5"	"2.3"	"2.8"	"13.1"	"5.0"	"18.1"	"50.2"	"86.8"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VTL8"	"Pre-mRNA-splicing factor 38B OS=Homo sapiens OX=9606 GN=PRPF38B PE=1 SV=1"	"3"	"2"	"4"	"2"	"546"	"64.4"	"10.54"	"579.54"	"6.59"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf03371"	"55119"	"ENSG00000134186"	"PRPF38B"	"hsa:55119; Q05DD6; Q32Q58; Q5VTL8; Q5VTL9; Q6PK39; Q7Z6E2; Q86WF3; Q8IWG9; Q9NW40"	""	""	"0"	"0"	"198.4"	"139.5"	"176.8"	"129.1"	"185.3"	"197.9"	"396.0"	"360.9"	"262.1"	"576.0"	"817.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19623"	"Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1"	"8"	"2"	"4"	"2"	"302"	"33.8"	"5.49"	"665.13"	"6.57"	"2"	"2"	"other metabolic processes;other biological processes"	"cytosol"	"other molecular function"	"Pf01564, Pf17284"	"6723"	"ENSG00000116649"	"SRM"	"B1AKP9; hsa:6723; P19623; Q15511"	"Methionine de novo and salvage pathway; Amino acid metabolism"	"Metabolism of polyamines"	"3"	"0"	"118.1"	"65.4"	"69.9"	"70.8"	"70.8"	"99.0"	"120.4"	"116.3"	"108.5"	"143.3"	"217.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60981"	"Destrin OS=Homo sapiens OX=9606 GN=DSTN PE=1 SV=3"	"18"	"3"	"6"	"2"	"165"	"18.5"	"7.85"	"859.90"	"6.57"	"2"	"3"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00241"	"11034"	"ENSG00000125868"	"DSTN"	"B2R6N2; B4DYA6; hsa:11034; P18282; P60981; Q5W166; Q6IAW2"	"Androgen receptor signaling pathway"	""	"1"	"0"	"46.0"	"25.0"	"47.9"	"35.4"	"42.7"	"50.2"	"71.8"	"75.6"	"63.4"	"132.0"	"242.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15050"	"Ribosome biogenesis regulatory protein homolog OS=Homo sapiens OX=9606 GN=RRS1 PE=1 SV=2"	"7"	"2"	"3"	"2"	"365"	"41.2"	"10.70"	"408.64"	"6.53"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity"	"Pf04939"	"23212"	"ENSG00000179041"	"RRS1"	"hsa:23212; Q15050; Q9BUX8"	""	""	"0"	"0"	"48.8"	"28.3"	"45.1"	"32.3"	"43.3"	"48.4"	"125.7"	"106.5"	"72.6"	"132.3"	"143.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y520"	"Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4"	"1"	"3"	"5"	"3"	"2896"	"316.7"	"9.13"	"1048.68"	"6.52"	"3"	"2"	"cell organization and biogenesis;other biological processes"	"cytosol;other cell component"	""	"Pf07001"	"23215"	"ENSG00000117523"	"PRRC2C"	"hsa:23215; Q05DM8; Q49A39; Q6PD54; Q9H2N2; Q9HA05; Q9NSM8; Q9NXL3; Q9UF29; Q9UPQ6; Q9Y520"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"27.9"	"21.8"	"28.7"	"24.7"	"29.8"	"28.5"	"161.3"	"158.3"	"123.7"	"165.9"	"189.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12904"	"Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1 PE=1 SV=2"	"11"	"3"	"5"	"3"	"312"	"34.3"	"8.43"	"824.36"	"6.52"	"3"	"2"	"cell-cell signaling;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf01588"	"9255"	"ENSG00000164022"	"AIMP1"	"B3KTR2; B4E1S7; hsa:9255; Q12904; Q6FG28; Q96CQ9"	"Ciliary landscape"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"3"	"0"	"120.2"	"55.4"	"92.5"	"97.3"	"105.2"	"108.0"	"240.9"	"234.4"	"171.7"	"304.8"	"488.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02790"	"Peptidyl-prolyl cis-trans isomerase FKBP4 OS=Homo sapiens OX=9606 GN=FKBP4 PE=1 SV=3"	"7"	"3"	"4"	"3"	"459"	"51.8"	"5.43"	"349.68"	"6.48"	"1"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00254, Pf00515"	"2288"	"ENSG00000004478"	"FKBP4"	"D3DUQ1; hsa:2288; Q02790; Q9UCP1; Q9UCV7"	"Androgen receptor signaling pathway"	"Estrogen-dependent gene expression; Potential therapeutics for SARS; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Attenuation phase"	"6"	"0"	"66.0"	"31.1"	"90.1"	"43.1"	"59.0"	"80.2"	"79.8"	"66.2"	"44.3"	"100.9"	"214.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BW85"	"Splicing factor YJU2 OS=Homo sapiens OX=9606 GN=YJU2 PE=1 SV=1"	"11"	"4"	"5"	"4"	"323"	"37.1"	"5.92"	"1316.21"	"6.48"	"3"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf04502"	"55702"	"ENSG00000105248"	"YJU2"	"hsa:55702; O75270; Q9BW85; Q9H862; Q9NW16"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"80.8"	"41.1"	"65.0"	"92.5"	"78.6"	"99.1"	"170.6"	"167.3"	"96.7"	"169.0"	"213.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49720"	"Proteasome subunit beta type-3 OS=Homo sapiens OX=9606 GN=PSMB3 PE=1 SV=2"	"15"	"2"	"4"	"2"	"205"	"22.9"	"6.55"	"711.22"	"6.48"	"2"	"2"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf00227"	"5691"	"ENSG00000275903; ENSG00000277791"	"PSMB3"	"hsa:5691; P31147; P49720; Q0P6J7; Q96E27"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"AUF1 (hnRNP D0) binds and destabilizes mRNA; MAPK6/MAPK4 signaling; Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"62"	"0"	"42.5"	"25.4"	"62.3"	"47.9"	"52.1"	"51.3"	"98.0"	"77.4"	"64.2"	"103.1"	"126.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48444"	"Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1"	"5"	"2"	"4"	"2"	"511"	"57.2"	"6.21"	"744.62"	"6.47"	"2"	"2"	"transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi"	""	"Pf00928, Pf01217"	"372"	"ENSG00000095139"	"ARCN1"	"B4E1X2; E9PEU4; hsa:372; P48444; Q52M80"	"miR-517 relationship with ARCN1 and USP1"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport"	"3"	"0"	"155.5"	"66.2"	"88.4"	"153.7"	"106.5"	"158.6"	"310.4"	"298.6"	"242.0"	"318.1"	"485.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00487"	"26S proteasome non-ATPase regulatory subunit 14 OS=Homo sapiens OX=9606 GN=PSMD14 PE=1 SV=1"	"6"	"2"	"5"	"2"	"310"	"34.6"	"6.52"	"1016.64"	"6.46"	"2"	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01398, Pf13012"	"10213"	"ENSG00000115233"	"PSMD14"	"B3KNW2; hsa:10213; O00176; O00487"	"Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"Antigen processing: Ubiquitination & Proteasome degradation; FCERI mediated NF-kB activation; Downstream TCR signaling; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Metalloprotease DUBs"	"64"	"0"	"112.1"	"69.8"	"107.5"	"89.2"	"104.7"	"113.5"	"130.2"	"135.2"	"95.6"	"164.0"	"212.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13363"	"C-terminal-binding protein 1 OS=Homo sapiens OX=9606 GN=CTBP1 PE=1 SV=2"	"5"	"2"	"4"	"1"	"440"	"47.5"	"6.77"	"728.95"	"6.46"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00389, Pf02826"	"1487"	"ENSG00000159692"	"CTBP1"	"hsa:1487; Q13363; Q4W5N3; Q7Z2Q5"	"Notch signaling; Ectoderm differentiation; Ectoderm differentiation; Wnt signaling pathway; Pathways affected in adenoid cystic carcinoma; Wnt signaling pathway and pluripotency; lncRNA in canonical Wnt signaling and colorectal cancer; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Pleural mesothelioma"	"SUMOylation of transcription cofactors; Deactivation of the beta-catenin transactivating complex; Repression of WNT target genes; Signaling by TCF7L2 mutants"	"14"	"0"	"8.0"	"7.8"	"17.5"	"9.7"	"11.2"	"13.3"	"19.7"	"15.7"	"8.5"	"20.0"	"26.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95639"	"Cleavage and polyadenylation specificity factor subunit 4 OS=Homo sapiens OX=9606 GN=CPSF4 PE=1 SV=1"	"13"	"2"	"3"	"2"	"269"	"30.2"	"8.31"	"357.92"	"6.45"	"1"	"2"	""	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00098, Pf00642, Pf15663"	"10898"	"ENSG00000160917"	"CPSF4"	"D6W5S8; hsa:10898; O95639; Q6FGE6; Q86TF8; Q9BTW6"	"mRNA processing"	"Transport of Mature mRNA Derived from an Intronless Transcript; tRNA processing in the nucleus; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; Inhibition of Host mRNA Processing and RNA Silencing"	"8"	"0"	"15.9"	"9.9"	"11.5"	"9.8"	"11.1"	"10.3"	"24.7"	"25.0"	"15.9"	"30.9"	"42.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BWF3"	"RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1"	"7"	"2"	"4"	"2"	"364"	"40.3"	"7.08"	"776.79"	"6.44"	"2"	"2"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00098"	"5936"	"ENSG00000173933"	"RBM4"	"B3KUN0; B4E1U0; E7EQS3; hsa:5936; O02916; Q4VC48; Q6P1P2; Q8WU85; Q9BWF3"	""	"Circadian Clock"	"1"	"0"	"121.4"	"90.7"	"119.6"	"121.3"	"127.4"	"133.6"	"241.2"	"240.0"	"194.5"	"277.7"	"276.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20618"	"Proteasome subunit beta type-1 OS=Homo sapiens OX=9606 GN=PSMB1 PE=1 SV=2"	"8"	"1"	"3"	"1"	"241"	"26.5"	"8.13"	"442.01"	"6.44"	"1"	"1"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf00227"	"5689"	"ENSG00000008018"	"PSMB1"	"B5BU76; hsa:5689; P20618; Q9BWA8"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A; MAPK6/MAPK4 signaling; The role of GTSE1 in G2/M progression after G2 checkpoint; Neutrophil degranulation; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"63"	"0"	"19.8"	"12.1"	"21.4"	"19.0"	"19.5"	"27.4"	"54.9"	"42.5"	"33.9"	"51.5"	"69.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P265"	"Disco-interacting protein 2 homolog B OS=Homo sapiens OX=9606 GN=DIP2B PE=1 SV=3"	"2"	"3"	"5"	"3"	"1576"	"171.4"	"8.09"	"981.29"	"6.42"	"3"	"2"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"cytoskeletal activity"	"Pf00501, Pf06464"	"57609"	"ENSG00000066084"	"DIP2B"	"hsa:57609; Q6B011; Q8N1L5; Q8NB38; Q9P265"	""	""	"0"	"0"	"37.0"	"26.7"	"36.2"	"36.2"	"43.0"	"44.4"	"122.5"	"190.5"	"157.7"	"247.2"	"355.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16543"	"Hsp90 co-chaperone Cdc37 OS=Homo sapiens OX=9606 GN=CDC37 PE=1 SV=1"	"6"	"2"	"3"	"2"	"378"	"44.4"	"5.25"	"437.06"	"6.41"	"1"	"2"	"protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity;other molecular function"	"Pf03234, Pf08564, Pf08565"	"11140"	"ENSG00000105401"	"CDC37"	"hsa:11140; Q16543; Q53YA2"	"TNF-alpha signaling pathway; Aryl hydrocarbon receptor pathway; Aryl hydrocarbon receptor pathway; Nuclear receptors meta-pathway; Interactions between LOXL4 and oxidative stress pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway"	"RHOBTB2 GTPase cycle; Signaling by ERBB2 KD Mutants; Signaling by ERBB2 TMD/JMD mutants; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; Constitutive Signaling by EGFRvIII; Signaling by ERBB2 ECD mutants; Constitutive Signaling by Overexpressed ERBB2; Regulation of necroptotic cell death; Downregulation of ERBB2 signaling; Drug-mediated inhibition of ERBB2 signaling; Resistance of ERBB2 KD mutants to trastuzumab; Resistance of ERBB2 KD mutants to sapitinib; Resistance of ERBB2 KD mutants to tesevatinib; Resistance of ERBB2 KD mutants to neratinib; Resistance of ERBB2 KD mutants to osimertinib; Resistance of ERBB2 KD mutants to afatinib; Resistance of ERBB2 KD mutants to AEE788; Resistance of ERBB2 KD mutants to lapatinib; Drug resistance in ERBB2 TMD/JMD mutants"	"27"	"0"	"131.9"	"57.9"	"105.9"	"106.3"	"96.2"	"119.7"	"186.1"	"167.8"	"112.7"	"184.8"	"279.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VT52"	"Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1"	"2"	"2"	"4"	"2"	"1461"	"155.9"	"7.42"	"676.18"	"6.39"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf04818"	"23248"	"ENSG00000163125"	"RPRD2"	"A8K6N8; B3KPT1; B4E2Q6; hsa:23248; O75048; Q5VT51; Q5VT52; Q5VT53; Q6MZL4; Q86XD2; Q9P0D7"	""	"RNA polymerase II transcribes snRNA genes"	"1"	"0"	"59.6"	"30.4"	"45.5"	"49.3"	"56.2"	"58.7"	"94.2"	"82.2"	"54.4"	"102.5"	"133.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQG0"	"Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2"	"2"	"2"	"3"	"2"	"1328"	"148.8"	"9.28"	"239.26"	"6.38"	"1"	"2"	"cell organization and biogenesis;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04931"	"10514"	"ENSG00000132382"	"MYBBP1A"	"hsa:10514; Q86VM3; Q9BQG0; Q9BW49; Q9P0V5; Q9UF99"	"Energy metabolism; 10q11.21q11.23 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression"	"3"	"0"	"19.5"	"15.2"	"27.2"	"16.1"	"13.7"	"16.8"	"27.9"	"28.3"	"23.3"	"30.3"	"41.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14157"	"Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2"	"3"	"3"	"5"	"3"	"1087"	"114.5"	"7.11"	"973.60"	"6.34"	"3"	"2"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	""	"Pf12478"	"9898"	"ENSG00000143569"	"UBAP2L"	"B4E0U8; hsa:9898; Q14157; Q5VU75; Q5VU76; Q9BTU3; Q9UGL2; Q9UGL3; Q9UGL4; Q9UGL5"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"200.1"	"111.1"	"145.1"	"144.8"	"132.5"	"173.8"	"356.0"	"352.3"	"249.1"	"382.0"	"535.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9GZT3"	"SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1"	"16"	"2"	"5"	"2"	"109"	"12.3"	"10.24"	"855.67"	"6.33"	"2"	"1"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;mitochondrion;nucleus;other cell component"	""	"Pf00076"	"81892"	"ENSG00000119705"	"SLIRP"	"hsa:81892; J3KMY7; Q9GZT3"	""	""	"0"	"0"	"421.4"	"197.4"	"297.3"	"304.0"	"321.3"	"354.8"	"630.4"	"619.4"	"433.8"	"618.0"	"825.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55036"	"26S proteasome non-ATPase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMD4 PE=1 SV=1"	"7"	"2"	"3"	"2"	"377"	"40.7"	"4.79"	"336.33"	"6.31"	"1"	"2"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf02809, Pf13519"	"5710"	"ENSG00000159352"	"PSMD4"	"D3DV16; hsa:5710; P55036; Q5VWC5; Q9NS92"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; VEGFA-VEGFR2 signaling; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"64"	"0"	"48.8"	"19.3"	"37.6"	"32.0"	"40.5"	"47.6"	"72.9"	"68.6"	"44.9"	"78.8"	"108.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86X55"	"Histone-arginine methyltransferase CARM1 OS=Homo sapiens OX=9606 GN=CARM1 PE=1 SV=3"	"4"	"1"	"1"	"1"	"608"	"65.8"	"6.73"	""	"6.31"	""	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06325, Pf11531"	"10498"	"ENSG00000142453"	"CARM1"	"A6NN38; hsa:10498; Q86X55"	"Androgen receptor signaling pathway; Nitric oxide metabolism in cystic fibrosis"	"Estrogen-dependent gene expression; PPARA activates gene expression; RMTs methylate histone arginines; Transcriptional regulation of white adipocyte differentiation; Heme signaling; BMAL1:CLOCK,NPAS2 activates circadian gene expression; Transcriptional activation of mitochondrial biogenesis; Cytoprotection by HMOX1; Activation of gene expression by SREBF (SREBP); TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; RORA activates gene expression"	"15"	"0"	"9.8"	"9.1"	"15.4"	"11.1"	"14.0"	"16.9"	"23.4"	"26.4"	"14.4"	"23.1"	"39.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BTC0"	"Death-inducer obliterator 1 OS=Homo sapiens OX=9606 GN=DIDO1 PE=1 SV=5"	"1"	"1"	"2"	"1"	"2240"	"243.7"	"7.88"	"517.21"	"6.31"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;signal transduction"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00628, Pf07500, Pf07744"	"11083"	"ENSG00000101191"	"DIDO1"	"A8MY65; B9EH82; E1P5I1; hsa:11083; O15043; Q3ZTL7; Q3ZTL8; Q4VXS1; Q4VXS2; Q4VXV8; Q4VXV9; Q96D72; Q9BQW0; Q9BTC0; Q9BW03; Q9H4G6; Q9H4G7; Q9NTU8; Q9NUM8; Q9UFB6"	""	""	"0"	"0"	"6.1"	"5.6"	"4.4"	"5.5"	"2.6"	"3.1"	"25.3"	"29.5"	"22.3"	"26.0"	"25.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5L4"	"Mitochondrial import inner membrane translocase subunit Tim13 OS=Homo sapiens OX=9606 GN=TIMM13 PE=1 SV=1"	"12"	"1"	"4"	"1"	"95"	"10.5"	"8.18"	"607.10"	"6.29"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf02953"	"26517"	"ENSG00000099800"	"TIMM13"	"hsa:26517; P62206; Q9UHL8; Q9WTL1; Q9Y5L4"	""	"Mitochondrial protein import"	"1"	"0"	"20.0"	"16.6"	"28.9"	"21.7"	"28.1"	"25.7"	"132.8"	"134.7"	"101.2"	"240.7"	"303.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94903"	"Pyridoxal phosphate homeostasis protein OS=Homo sapiens OX=9606 GN=PLPBP PE=1 SV=1"	"8"	"2"	"4"	"2"	"275"	"30.3"	"7.50"	"661.64"	"6.26"	"2"	"2"	""	"cytosol;other cell component"	"other molecular function"	"Pf01168"	"11212"	"ENSG00000147471"	"PLPBP"	"hsa:11212; O94903; Q6FI94"	""	""	"0"	"0"	"23.0"	"20.6"	"32.1"	"27.3"	"31.8"	"27.5"	"43.2"	"37.7"	"32.1"	"115.3"	"333.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P015"	"39S ribosomal protein L15, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL15 PE=1 SV=1"	"7"	"2"	"4"	"2"	"296"	"33.4"	"10.01"	"805.02"	"6.25"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00828"	"29088"	"ENSG00000137547"	"MRPL15"	"hsa:29088; Q96Q54; Q9H0Y1; Q9P015"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"166.6"	"96.7"	"139.0"	"136.4"	"139.2"	"164.9"	"262.8"	"240.1"	"184.3"	"317.3"	"445.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P0K7"	"Ankycorbin OS=Homo sapiens OX=9606 GN=RAI14 PE=1 SV=2"	"2"	"2"	"4"	"1"	"980"	"110.0"	"6.21"	"649.90"	"6.25"	"2"	"2"	"other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf00023, Pf12796"	"26064"	"ENSG00000039560"	"RAI14"	"E9PED3; hsa:26064; Q6V1W9; Q7Z5I4; Q7Z733; Q9P0K7; Q9P2L2; Q9Y3T5"	""	""	"0"	"0"	"9.1"	"4.6"	"10.4"	"9.5"	"8.2"	"12.4"	"19.5"	"20.0"	"11.3"	"24.1"	"38.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99569"	"Plakophilin-4 OS=Homo sapiens OX=9606 GN=PKP4 PE=1 SV=2"	"3"	"2"	"4"	"2"	"1192"	"131.8"	"8.94"	"642.42"	"6.25"	"2"	"2"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00514"	"8502"	"ENSG00000144283"	"PKP4"	"hsa:8502; Q86W91; Q99569"	""	"Formation of the cornified envelope; RND2 GTPase cycle; RND1 GTPase cycle; RND3 GTPase cycle"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14406"	"Cytochrome c oxidase subunit 7A2, mitochondrial OS=Homo sapiens OX=9606 GN=COX7A2 PE=1 SV=1"	"28"	"2"	"4"	"2"	"83"	"9.4"	"9.76"	"687.65"	"6.24"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf02238"	"1347"	"ENSG00000112695"	"COX7A2"	"B2R5E1; hsa:1347; P14406; Q3MIH5; Q5TF59; Q6FGI2"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly"	""	"3"	"0"	"281.0"	"214.1"	"226.6"	"167.6"	"215.4"	"261.0"	"386.6"	"327.1"	"266.1"	"486.0"	"667.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NQT4"	"Exosome complex component RRP46 OS=Homo sapiens OX=9606 GN=EXOSC5 PE=1 SV=1"	"8"	"2"	"4"	"2"	"235"	"25.2"	"7.59"	"736.38"	"6.21"	"2"	"2"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01138, Pf03725"	"56915"	"ENSG00000077348"	"EXOSC5"	"hsa:56915; Q32Q81; Q8NG16; Q96I89; Q9NQT4"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	"6"	"0"	"147.8"	"90.3"	"151.2"	"137.3"	"138.2"	"147.5"	"297.4"	"282.4"	"195.7"	"328.8"	"483.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51398"	"28S ribosomal protein S29, mitochondrial OS=Homo sapiens OX=9606 GN=DAP3 PE=1 SV=1"	"6"	"2"	"4"	"2"	"398"	"45.5"	"8.88"	"607.26"	"6.19"	"2"	"2"	"protein metabolism;other metabolic processes;signal transduction"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf10236"	"7818"	"ENSG00000132676"	"DAP3"	"B4DP59; B4DY62; E7EM60; hsa:7818; P51398; Q13044; Q68CT7; Q96Q20"	"CKAP4 signaling pathway map"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"4"	"0"	"461.9"	"101.1"	"181.7"	"170.3"	"180.2"	"188.7"	"324.9"	"291.2"	"171.6"	"286.8"	"484.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75348"	"V-type proton ATPase subunit G 1 OS=Homo sapiens OX=9606 GN=ATP6V1G1 PE=1 SV=3"	"17"	"2"	"4"	"2"	"118"	"13.7"	"8.79"	"811.12"	"6.16"	"2"	"2"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf03179"	"9550"	"ENSG00000136888"	"ATP6V1G1"	"hsa:9550; O75348; Q6IB33"	"Osteoclast signaling; Proximal tubule transport"	"Amino acids regulate mTORC1; ROS and RNS production in phagocytes; Insulin receptor recycling; Transferrin endocytosis and recycling; Ion channel transport"	"7"	"0"	"82.8"	"36.2"	"66.4"	"72.0"	"71.8"	"72.2"	"216.6"	"212.7"	"182.7"	"241.7"	"384.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UHR5"	"SAP30-binding protein OS=Homo sapiens OX=9606 GN=SAP30BP PE=1 SV=1"	"6"	"2"	"3"	"2"	"308"	"33.9"	"4.84"	"585.27"	"6.16"	"1"	"2"	"other biological processes"	"cytoskeleton;nucleus"	""	"Pf07818"	"29115"	"ENSG00000161526"	"SAP30BP"	"B3KML7; hsa:29115; Q8N1R5; Q8TDR8; Q96D27; Q9UHR5"	""	"NoRC negatively regulates rRNA expression"	"1"	"0"	"10.1"	"7.5"	"8.2"	"10.8"	"8.6"	"13.6"	"21.9"	"28.1"	"25.1"	"25.8"	"32.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WVC0"	"RNA polymerase-associated protein LEO1 OS=Homo sapiens OX=9606 GN=LEO1 PE=1 SV=1"	"4"	"4"	"6"	"4"	"666"	"75.4"	"4.51"	"1169.23"	"6.14"	"4"	"2"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytoskeleton;nucleus"	"other molecular function"	"Pf04004"	"123169"	"ENSG00000166477"	"LEO1"	"hsa:123169; Q8WVC0; Q96N99"	"Endoderm differentiation"	"E3 ubiquitin ligases ubiquitinate target proteins; Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events; Formation of the beta-catenin:TCF transactivating complex"	"6"	"0"	"275.9"	"157.1"	"214.5"	"211.8"	"197.9"	"257.4"	"763.4"	"737.0"	"517.6"	"829.0"	"1169.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75347"	"Tubulin-specific chaperone A OS=Homo sapiens OX=9606 GN=TBCA PE=1 SV=3"	"19"	"2"	"4"	"2"	"108"	"12.8"	"5.29"	"758.19"	"6.12"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02970"	"6902"	"ENSG00000171530"	"TBCA"	"B4DT30; hsa:6902; O75347"	"VEGFA-VEGFR2 signaling"	"Post-chaperonin tubulin folding pathway"	"2"	"0"	"175.6"	"131.5"	"145.2"	"94.9"	"155.7"	"169.0"	"193.9"	"148.4"	"124.6"	"195.9"	"319.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86VN1"	"Vacuolar protein-sorting-associated protein 36 OS=Homo sapiens OX=9606 GN=VPS36 PE=1 SV=1"	"6"	"2"	"3"	"2"	"386"	"43.8"	"7.20"	"384.41"	"6.12"	"1"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport"	"other membranes;cytosol;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf04157, Pf11605"	"51028"	"ENSG00000136100"	"VPS36"	"A8K125; hsa:51028; Q3ZCV7; Q5H9S1; Q5VXB6; Q86VN1; Q9H8Z5; Q9Y3E3"	"Network map of SARS-CoV-2 signaling pathway"	"Endosomal Sorting Complex Required For Transport (ESCRT); HCMV Late Events"	"3"	"0"	"17.0"	"13.3"	"31.6"	"14.9"	"26.2"	"22.1"	"39.0"	"41.3"	"44.9"	"91.7"	"119.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NZR1"	"Tropomodulin-2 OS=Homo sapiens OX=9606 GN=TMOD2 PE=1 SV=1"	"5"	"2"	"4"	"1"	"351"	"39.6"	"5.27"	"623.89"	"6.10"	"2"	"2"	"cell-cell signaling;cell organization and biogenesis;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf03250"	"29767"	"ENSG00000128872"	"TMOD2"	"B4DEW6; hsa:29767; Q9NZR1"	""	"Striated Muscle Contraction"	"1"	"0"	"63.5"	"42.1"	"66.4"	"45.2"	"53.0"	"57.8"	"65.9"	"51.4"	"43.7"	"72.8"	"131.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96AY3"	"Peptidyl-prolyl cis-trans isomerase FKBP10 OS=Homo sapiens OX=9606 GN=FKBP10 PE=1 SV=1"	"3"	"2"	"4"	"2"	"582"	"64.2"	"5.62"	"699.10"	"6.08"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes"	"other membranes;mitochondrion;ER/Golgi"	"other molecular function"	"Pf00254, Pf13202"	"60681"	"ENSG00000141756"	"FKBP10"	"hsa:60681; Q7Z3R4; Q96AY3; Q9H3N3; Q9H6J3; Q9H6N5; Q9UF89"	"Type I collagen synthesis in the context of osteogenesis imperfecta"	""	"1"	"0"	"170.7"	"110.8"	"150.1"	"144.1"	"151.0"	"169.6"	"231.6"	"199.3"	"149.7"	"263.0"	"386.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TAD8"	"Smad nuclear-interacting protein 1 OS=Homo sapiens OX=9606 GN=SNIP1 PE=1 SV=1"	"5"	"1"	"2"	"1"	"396"	"45.8"	"9.99"	"747.14"	"6.08"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity"	"Pf00498"	"79753"	"ENSG00000163877"	"SNIP1"	"hsa:79753; Q8TAD8; Q96SP9; Q9H9T7"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"45.0"	"20.0"	"31.9"	"44.9"	"31.7"	"37.7"	"79.6"	"84.3"	"58.9"	"95.3"	"124.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q04637"	"Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4"	"2"	"3"	"5"	"3"	"1599"	"175.4"	"5.33"	"1141.98"	"6.07"	"3"	"2"	"protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02020, Pf02847, Pf02854"	"1981"	"ENSG00000114867"	"EIF4G1"	"D3DNT2; D3DNT4; D3DNT5; E9PFM1; G5E9S1; hsa:1981; O43177; O95066; Q04637; Q5HYG0; Q6ZN21; Q8N102"	"Translation factors; VEGFA-VEGFR2 signaling; Acute viral myocarditis; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Pleural mesothelioma"	"ISG15 antiviral mechanism; AUF1 (hnRNP D0) binds and destabilizes mRNA; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Deadenylation of mRNA; mTORC1-mediated signalling"	"18"	"0"	"42.5"	"32.4"	"30.1"	"27.2"	"32.6"	"36.8"	"80.8"	"62.5"	"54.6"	"82.4"	"115.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRV9"	"Heme-binding protein 1 OS=Homo sapiens OX=9606 GN=HEBP1 PE=1 SV=1"	"11"	"2"	"4"	"2"	"189"	"21.1"	"5.80"	"655.03"	"6.06"	"2"	"2"	"other biological processes"	"non-structural extracellular;other cell component"	"other molecular function"	"Pf04832"	"50865"	"ENSG00000013583"	"HEBP1"	"A8K1G2; hsa:50865; Q9NRV9; Q9Y5Z5"	""	"G alpha (i) signalling events; Formyl peptide receptors bind formyl peptides and many other ligands"	"2"	"0"	"141.1"	"70.4"	"67.1"	"116.3"	"77.8"	"116.2"	"204.8"	"234.4"	"174.3"	"248.4"	"350.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43813"	"Glutathione S-transferase LANCL1 OS=Homo sapiens OX=9606 GN=LANCL1 PE=1 SV=1"	"6"	"2"	"4"	"2"	"399"	"45.3"	"7.75"	"741.34"	"6.05"	"2"	"2"	"other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf05147"	"10314"	"ENSG00000115365"	"LANCL1"	"hsa:10314; O43813"	""	""	"0"	"0"	"63.8"	"38.1"	"65.0"	"62.3"	"53.4"	"82.9"	"227.0"	"204.1"	"171.5"	"231.9"	"253.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95347"	"Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2"	"2"	"2"	"4"	"2"	"1197"	"135.6"	"8.43"	"684.03"	"6.04"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463, Pf06470"	"10592"	"ENSG00000136824"	"SMC2"	"hsa:10592; O95347; Q6IEE0; Q9P1P2"	"Retinoblastoma gene in cancer"	"Condensation of Prophase Chromosomes; Condensation of Prometaphase Chromosomes"	"3"	"0"	"51.6"	"28.7"	"58.0"	"49.6"	"53.2"	"66.4"	"231.5"	"229.0"	"153.4"	"278.9"	"304.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TDN6"	"Ribosome biogenesis protein BRX1 homolog OS=Homo sapiens OX=9606 GN=BRIX1 PE=1 SV=2"	"7"	"2"	"4"	"2"	"353"	"41.4"	"9.92"	"607.01"	"6.03"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf04427"	"55299"	"ENSG00000113460"	"BRIX1"	"A8K0P5; hsa:55299; Q3ZTT4; Q8N453; Q8TDN6; Q96DH1"	"Gastric cancer network 2"	""	"1"	"0"	"20.1"	"15.6"	"27.4"	"13.9"	"19.6"	"24.0"	"63.0"	"56.8"	"37.2"	"71.8"	"81.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IVS2"	"Malonyl-CoA-acyl carrier protein transacylase, mitochondrial OS=Homo sapiens OX=9606 GN=MCAT PE=1 SV=2"	"6"	"2"	"3"	"2"	"390"	"42.9"	"8.72"	"369.87"	"6.02"	"1"	"2"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00698"	"27349"	"ENSG00000100294"	"MCAT"	"B0QY72; hsa:27349; O95510; O95511; Q8IVS2"	"Mitochondrial fatty acid synthesis pathway"	"Mitochondrial Fatty Acid Beta-Oxidation"	"2"	"0"	"60.6"	"38.8"	"58.8"	"61.1"	"68.1"	"73.3"	"203.4"	"175.6"	"154.7"	"270.6"	"315.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P54727"	"UV excision repair protein RAD23 homolog B OS=Homo sapiens OX=9606 GN=RAD23B PE=1 SV=1"	"6"	"3"	"5"	"1"	"409"	"43.1"	"4.84"	"991.95"	"6.02"	"3"	"2"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00240, Pf00627, Pf09280"	"5887"	"ENSG00000119318"	"RAD23B"	"B3KWK8; G5E9P0; hsa:5887; P54727; Q7Z5K8; Q8WUB0"	"Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"Josephin domain DUBs; Formation of Incision Complex in GG-NER; DNA Damage Recognition in GG-NER; N-glycan trimming in the ER and Calnexin/Calreticulin cycle"	"7"	"2"	"891.2"	"394.9"	"494.8"	"635.3"	"525.6"	"627.3"	"902.6"	"822.3"	"690.8"	"926.1"	"1349.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IXQ4"	"GPALPP motifs-containing protein 1 OS=Homo sapiens OX=9606 GN=GPALPP1 PE=1 SV=1"	"6"	"2"	"4"	"2"	"340"	"38.1"	"5.41"	"590.98"	"6.00"	"2"	"2"	""	""	""	"Pf12572"	"55425"	"ENSG00000133114"	"GPALPP1"	"A8K8X8; hsa:55425; Q05BX8; Q05D87; Q5T3Z3; Q5T3Z5; Q8IXQ4; Q9C0F9; Q9H2R0; Q9P0W6"	""	""	"0"	"0"	"107.2"	"48.6"	"88.8"	"105.6"	"114.4"	"110.4"	"328.0"	"274.7"	"191.8"	"306.0"	"440.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5Q9"	"General transcription factor 3C polypeptide 3 OS=Homo sapiens OX=9606 GN=GTF3C3 PE=1 SV=1"	"2"	"2"	"4"	"2"	"886"	"101.2"	"5.07"	"704.79"	"5.99"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13181"	"9330"	"ENSG00000119041"	"GTF3C3"	"hsa:9330; Q4ZG48; Q86XJ8; Q8WX84; Q96B44; Q9H5I8; Q9NT97; Q9Y5Q9"	""	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter"	"3"	"0"	"146.2"	"82.9"	"118.1"	"140.0"	"143.9"	"160.2"	"308.7"	"270.9"	"195.0"	"299.7"	"412.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HD33"	"39S ribosomal protein L47, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL47 PE=1 SV=2"	"7"	"2"	"4"	"2"	"250"	"29.4"	"10.37"	"637.93"	"5.96"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf06984"	"57129"	"ENSG00000136522"	"MRPL47"	"hsa:57129; Q6XRG1; Q8N5D1; Q9HD33"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"58.0"	"39.4"	"64.4"	"51.7"	"50.8"	"63.0"	"118.4"	"114.4"	"82.2"	"130.3"	"170.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96HS1"	"Serine/threonine-protein phosphatase PGAM5, mitochondrial OS=Homo sapiens OX=9606 GN=PGAM5 PE=1 SV=2"	"7"	"2"	"4"	"2"	"289"	"32.0"	"8.68"	"626.01"	"5.95"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion"	"enzyme regulator activity;other molecular function"	"Pf00300"	"192111"	"ENSG00000247077"	"PGAM5"	"A9LN06; C9IZY7; hsa:192111; Q96HS1; Q96JB0"	"NRF2-ARE regulation"	""	"1"	"0"	"203.5"	"148.7"	"200.2"	"170.3"	"196.8"	"212.2"	"374.7"	"362.4"	"266.7"	"407.8"	"509.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15075"	"Early endosome antigen 1 OS=Homo sapiens OX=9606 GN=EEA1 PE=1 SV=2"	"3"	"3"	"4"	"3"	"1411"	"162.4"	"5.68"	"765.87"	"5.94"	"2"	"2"	"cell-cell signaling;cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01363"	"8411"	"ENSG00000102189"	"EEA1"	"hsa:8411; Q14221; Q15075"	"VEGFA-VEGFR2 signaling"	"Toll Like Receptor 9 (TLR9) Cascade"	"2"	"0"	"3.8"	"2.2"	"0.0"	"3.5"	"5.5"	"4.9"	"23.2"	"29.2"	"25.9"	"33.9"	"57.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P24666"	"Low molecular weight phosphotyrosine protein phosphatase OS=Homo sapiens OX=9606 GN=ACP1 PE=1 SV=3"	"13"	"2"	"4"	"2"	"158"	"18.0"	"6.74"	"593.29"	"5.94"	"2"	"2"	"protein metabolism;other metabolic processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf01451"	"52"	"ENSG00000143727"	"ACP1"	"A8K1L9; B5MCC7; hsa:52; P24666; P24667; Q16035; Q16036; Q16725; Q3KQX8; Q53RU0"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"66.1"	"43.5"	"49.3"	"44.6"	"56.0"	"55.3"	"70.1"	"73.9"	"62.4"	"101.3"	"114.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62191"	"26S proteasome regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMC1 PE=1 SV=1"	"8"	"3"	"5"	"3"	"440"	"49.2"	"6.21"	"1226.46"	"5.93"	"3"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf16450, Pf17862"	"5700"	"ENSG00000100764"	"PSMC1"	"B4DR63; hsa:5700; P49014; P62191; Q03527; Q6IAW0; Q6NW36; Q96AZ3"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; N-glycan trimming in the ER and Calnexin/Calreticulin cycle"	"64"	"0"	"249.1"	"105.7"	"198.6"	"175.4"	"185.7"	"194.5"	"319.5"	"307.8"	"194.2"	"343.5"	"494.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P29372"	"DNA-3-methyladenine glycosylase OS=Homo sapiens OX=9606 GN=MPG PE=1 SV=3"	"8"	"2"	"4"	"2"	"298"	"32.8"	"9.57"	"597.55"	"5.93"	"2"	"2"	"DNA metabolism;other metabolic processes;stress response"	"cytosol;mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf02245"	"4350"	"ENSG00000103152"	"MPG"	"G5E9E2; hsa:4350; P29372; Q13770; Q15275; Q15961; Q5J9I4; Q96BZ6; Q96S33; Q9NNX5"	"Base excision repair; DNA repair pathways, full network"	"Recognition and association of DNA glycosylase with site containing an affected purine; Cleavage of the damaged purine; Displacement of DNA glycosylase by APEX1"	"5"	"0"	"79.9"	"46.3"	"80.0"	"71.1"	"76.4"	"80.1"	"303.0"	"264.6"	"220.3"	"321.4"	"362.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y608"	"Leucine-rich repeat flightless-interacting protein 2 OS=Homo sapiens OX=9606 GN=LRRFIP2 PE=1 SV=1"	"4"	"2"	"4"	"2"	"721"	"82.1"	"6.95"	"612.94"	"5.92"	"2"	"2"	"cell-cell signaling;signal transduction;other biological processes"	""	"other molecular function"	"Pf09738"	"9209"	"ENSG00000093167"	"LRRFIP2"	"A8K649; A8MXR0; B4DY63; hsa:9209; Q68CV3; Q9NXH5; Q9Y608"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49790"	"Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2"	"1"	"2"	"3"	"2"	"1475"	"153.8"	"8.73"	"401.43"	"5.92"	"1"	"2"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00641, Pf08604, Pf10599"	"9972"	"ENSG00000124789"	"NUP153"	"B4DIK2; E7EPX5; F6QR24; hsa:9972; P49790; Q4LE47; Q5T9I7; Q7Z743"	""	"Nuclear import of Rev protein; HCMV Late Events; HCMV Early Events; Transcriptional regulation by small RNAs; SUMOylation of DNA replication proteins; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"28"	"0"	"101.3"	"62.2"	"103.4"	"103.2"	"95.7"	"96.3"	"196.7"	"191.8"	"139.4"	"202.5"	"243.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P587"	"Acylpyruvase FAHD1, mitochondrial OS=Homo sapiens OX=9606 GN=FAHD1 PE=1 SV=2"	"10"	"2"	"4"	"2"	"224"	"24.8"	"7.39"	"671.23"	"5.91"	"2"	"2"	"other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf01557"	"81889"	"ENSG00000180185"	"FAHD1"	"B1AK40; B1AK41; hsa:81889; Q6FIC7; Q6P587; Q96RY1; Q9H0N6"	""	"Citric acid cycle (TCA cycle)"	"1"	"0"	"54.0"	"30.2"	"54.1"	"50.2"	"54.8"	"56.2"	"116.9"	"98.7"	"80.0"	"147.5"	"219.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H5V9"	"UPF0428 protein CXorf56 OS=Homo sapiens OX=9606 GN=CXorf56 PE=1 SV=1"	"17"	"4"	"6"	"4"	"222"	"25.6"	"8.73"	"1085.91"	"5.91"	"4"	"2"	"cell organization and biogenesis;transport"	"cytoskeleton;nucleus;other cell component"	""	""	"63932"	"ENSG00000018610"	"STEEP1"	"A8MPX7; B4DQN2; D3DWH9; F5GWL7; hsa:63932; O43351; Q9H5V9"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"197.5"	"114.1"	"159.1"	"171.0"	"161.6"	"179.5"	"609.9"	"556.6"	"392.2"	"605.3"	"792.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07947"	"Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3"	"4"	"2"	"3"	"1"	"543"	"60.8"	"6.74"	"467.01"	"5.88"	"1"	"2"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf00017, Pf00018, Pf07714"	"7525"	"ENSG00000176105"	"YES1"	"A6NLB3; D3DUH1; hsa:7525; P07947"	"Thymic stromal lymphopoietin (TSLP) signaling pathway; Interleukin-11 signaling pathway; NRF2-ARE regulation; Gastrin signaling pathway; GDNF signaling"	"FCGR activation; FCGR3A-mediated IL10 synthesis; FCGR3A-mediated phagocytosis; Regulation of signaling by CBL; EPHB-mediated forward signaling; Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants; Regulation of KIT signaling; Signaling by ERBB2; EPH-ephrin mediated repulsion of cells; EPHA-mediated growth cone collapse; Signaling by CSF1 (M-CSF) in myeloid cells; RUNX2 regulates osteoblast differentiation; CD28 co-stimulation; PECAM1 interactions; CTLA4 inhibitory signaling"	"22"	"1"	"183.4"	"106.2"	"133.1"	"152.8"	"151.8"	"159.5"	"224.8"	"232.2"	"181.0"	"262.5"	"313.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2D5"	"A-kinase anchor protein 2 OS=Homo sapiens OX=9606 GN=AKAP2 PE=1 SV=3"	"3"	"2"	"4"	"2"	"859"	"94.6"	"5.11"	"818.81"	"5.86"	"2"	"2"	""	""	""	"Pf15304"	"445815"	""	"AKAP2"	"B1ALX9; B2RTU4; B3KQ00; B4DTZ2; B7ZW07; B9EJB5; Q9UG26; Q9Y2D5"	""	""	"0"	"0"	"23.4"	"13.0"	"24.0"	"21.8"	"17.0"	"23.5"	"60.6"	"53.6"	"40.6"	"70.9"	"87.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H857"	"5'-nucleotidase domain-containing protein 2 OS=Homo sapiens OX=9606 GN=NT5DC2 PE=1 SV=1"	"5"	"2"	"3"	"2"	"520"	"60.7"	"6.77"	"308.42"	"5.83"	"1"	"2"	""	""	"other molecular function"	"Pf05761"	"64943"	"ENSG00000168268"	"NT5DC2"	"C9JTZ6; E9PAL9; hsa:64943; O95888; Q96C80; Q9H857; Q9H9Z8"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H0G5"	"Nuclear speckle splicing regulatory protein 1 OS=Homo sapiens OX=9606 GN=NSRP1 PE=1 SV=1"	"3"	"2"	"4"	"2"	"558"	"66.4"	"8.84"	"754.94"	"5.82"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf09745, Pf20427"	"84081"	"ENSG00000126653"	"NSRP1"	"hsa:84081; Q6FI71; Q9H0G5"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"127.3"	"60.4"	"72.1"	"98.9"	"87.8"	"98.8"	"256.6"	"227.5"	"180.6"	"287.7"	"413.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5B9"	"FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1"	"2"	"2"	"4"	"2"	"1047"	"119.8"	"5.66"	"631.88"	"5.80"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus"	"other molecular function"	"Pf00557, Pf08512, Pf08644, Pf14826"	"11198"	"ENSG00000092201"	"SUPT16H"	"hsa:11198; Q6GMT8; Q6P2F1; Q6PJM1; Q9NRX0; Q9Y5B9"	""	"Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; Regulation of TP53 Activity through Phosphorylation"	"12"	"0"	"14.3"	"11.6"	"18.1"	"11.6"	"18.6"	"14.6"	"58.3"	"56.8"	"35.3"	"65.1"	"84.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13769"	"THO complex subunit 5 homolog OS=Homo sapiens OX=9606 GN=THOC5 PE=1 SV=2"	"4"	"2"	"4"	"2"	"683"	"78.5"	"6.87"	"591.41"	"5.80"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf09766"	"8563"	"ENSG00000100296"	"THOC5"	"hsa:8563; O60839; Q13769; Q9UPZ5"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Signaling by CSF1 (M-CSF) in myeloid cells"	"4"	"0"	"81.9"	"63.3"	"96.9"	"83.8"	"93.6"	"113.4"	"178.2"	"172.6"	"119.4"	"203.2"	"250.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00743"	"Serine/threonine-protein phosphatase 6 catalytic subunit OS=Homo sapiens OX=9606 GN=PPP6C PE=1 SV=1"	"7"	"2"	"4"	"2"	"305"	"35.1"	"5.69"	"638.13"	"5.80"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00149"	"5537"	"ENSG00000119414"	"PPP6C"	"B2R5V6; B7Z2W9; B7Z5K9; hsa:5537; O00743; Q5U0A2; Q9UIC9"	""	"Telomere Extension By Telomerase; COPII-mediated vesicle transport"	"2"	"0"	"78.7"	"39.9"	"71.4"	"56.7"	"71.2"	"62.8"	"120.1"	"110.1"	"89.9"	"123.8"	"153.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NAV1"	"Pre-mRNA-splicing factor 38A OS=Homo sapiens OX=9606 GN=PRPF38A PE=1 SV=1"	"4"	"1"	"2"	"1"	"312"	"37.5"	"9.96"	"568.52"	"5.79"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf03371, Pf12871"	"84950"	"ENSG00000134748"	"PRPF38A"	"hsa:84950; Q8NAV1; Q96JW1; Q9BVZ8"	"MECP2 and associated Rett syndrome"	"mRNA Splicing - Major Pathway"	"2"	"0"	"9.7"	"6.0"	"6.8"	"10.5"	"11.9"	"12.2"	"22.0"	"18.8"	"20.3"	"28.3"	"36.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62875"	"DNA-directed RNA polymerases I, II, and III subunit RPABC5 OS=Homo sapiens OX=9606 GN=POLR2L PE=1 SV=1"	"30"	"2"	"4"	"2"	"67"	"7.6"	"7.77"	"729.52"	"5.79"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01194"	"5441"	"ENSG00000177700"	"POLR2L"	"hsa:5441; P52436; P62875; Q6FHX3"	"Pyrimidine metabolism; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; B-WICH complex positively regulates rRNA expression; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; mRNA Splicing - Major Pathway; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"56"	"0"	"46.5"	"39.2"	"54.5"	"53.3"	"50.4"	"55.6"	"115.7"	"164.0"	"152.0"	"279.4"	"342.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00299"	"Chloride intracellular channel protein 1 OS=Homo sapiens OX=9606 GN=CLIC1 PE=1 SV=4"	"11"	"2"	"4"	"2"	"241"	"26.9"	"5.17"	"614.15"	"5.78"	"2"	"2"	"transport;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;mitochondrion;nucleus;other cell component"	"transporter activity"	"Pf13409, Pf13410"	"1192"	"ENSG00000206394; ENSG00000213719; ENSG00000223639; ENSG00000226248; ENSG00000226417; ENSG00000226651; ENSG00000230685"	"CLIC1"	"hsa:1192; O00299; Q15089; Q502X1"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"74.1"	"51.0"	"61.5"	"67.9"	"66.3"	"61.9"	"107.8"	"97.4"	"75.4"	"119.8"	"178.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49411"	"Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2"	"7"	"3"	"5"	"3"	"452"	"49.5"	"7.61"	"1164.86"	"5.77"	"3"	"2"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"437.3"	"288.5"	"338.4"	"378.5"	"421.5"	"470.0"	"687.7"	"682.6"	"527.0"	"781.3"	"1070.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00403"	"Cytochrome c oxidase subunit 2 OS=Homo sapiens OX=9606 GN=MT-CO2 PE=1 SV=1"	"18"	"3"	"4"	"3"	"227"	"25.5"	"4.82"	"607.43"	"5.77"	"2"	"2"	"other metabolic processes;stress response;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00116, Pf02790"	"4513"	"ENSG00000198712"	"MT-CO2"	"hsa:4513; P00403; Q37526"	"Electron transport chain: OXPHOS system in mitochondria; Endothelin pathways; EGF/EGFR signaling pathway; Nonalcoholic fatty liver disease; Neuroinflammation; Mitochondrial complex IV assembly; CCL18 signaling pathway; 5q35 copy number variation"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"11"	"0"	"81.7"	"69.7"	"84.3"	"51.0"	"76.6"	"74.6"	"110.5"	"98.0"	"86.4"	"167.6"	"172.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14696"	"LRP chaperone MESD OS=Homo sapiens OX=9606 GN=MESD PE=1 SV=2"	"9"	"2"	"4"	"2"	"234"	"26.1"	"7.78"	"676.71"	"5.76"	"2"	"2"	"cell-cell signaling;protein metabolism;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi"	"signal transduction activity or receptor binding;other molecular function"	"Pf10185"	"23184"	"ENSG00000117899"	"MESD"	"B4DW84; D3DW96; hsa:23184; Q14696; Q969U1"	""	""	"0"	"0"	"101.1"	"44.7"	"69.4"	"72.6"	"83.4"	"76.4"	"132.6"	"119.8"	"101.3"	"157.7"	"240.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N488"	"RING1 and YY1-binding protein OS=Homo sapiens OX=9606 GN=RYBP PE=1 SV=2"	"12"	"2"	"3"	"2"	"228"	"24.8"	"9.63"	"309.59"	"5.75"	"1"	"2"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00641, Pf17219"	"23429"	"ENSG00000163602; ENSG00000281766"	"RYBP"	"hsa:23429; Q8N488; Q9P2W5; Q9UMW4"	""	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Transcriptional Regulation by E2F6"	"2"	"0"	"99.0"	"54.3"	"95.3"	"120.5"	"118.7"	"116.5"	"315.0"	"260.7"	"153.3"	"268.4"	"389.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61970"	"Nuclear transport factor 2 OS=Homo sapiens OX=9606 GN=NUTF2 PE=1 SV=1"	"24"	"3"	"5"	"3"	"127"	"14.5"	"5.38"	"977.50"	"5.73"	"3"	"2"	"transport;other biological processes"	"other membranes;cytosol;nucleus"	"other molecular function"	"Pf02136"	"10204"	"ENSG00000102898"	"NUTF2"	"B2R4G7; hsa:10204; P13662; P61970; Q6IB67"	""	""	"0"	"0"	"295.2"	"224.3"	"356.4"	"163.8"	"248.3"	"301.5"	"328.1"	"238.4"	"196.5"	"411.0"	"544.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H0C8"	"Integrin-linked kinase-associated serine/threonine phosphatase 2C OS=Homo sapiens OX=9606 GN=ILKAP PE=1 SV=1"	"5"	"2"	"4"	"2"	"392"	"42.9"	"7.09"	"674.58"	"5.72"	"2"	"2"	"protein metabolism;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00481"	"80895"	"ENSG00000132323"	"ILKAP"	"B3KM39; hsa:80895; Q9H0C8"	"2q37 copy number variation syndrome"	""	"1"	"0"	"66.8"	"52.0"	"62.4"	"71.0"	"66.7"	"87.2"	"222.9"	"215.9"	"174.8"	"222.2"	"325.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IVD9"	"NudC domain-containing protein 3 OS=Homo sapiens OX=9606 GN=NUDCD3 PE=1 SV=3"	"6"	"2"	"3"	"2"	"361"	"40.8"	"5.25"	"307.31"	"5.72"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;other cell component"	"other molecular function"	"Pf04969, Pf14050"	"23386"	"ENSG00000015676"	"NUDCD3"	"hsa:23386; Q8IVD9; Q9BTI3; Q9H7W9; Q9UPT4"	""	""	"0"	"0"	"109.3"	"58.3"	"75.8"	"107.3"	"88.5"	"119.1"	"166.5"	"157.5"	"103.7"	"178.1"	"224.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7RTN6"	"STE20-related kinase adapter protein alpha OS=Homo sapiens OX=9606 GN=STRADA PE=1 SV=1"	"7"	"2"	"4"	"2"	"431"	"48.3"	"6.48"	"556.64"	"5.71"	"2"	"2"	"cell cycle OR cell proliferation;transport;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00069"	"92335"	"ENSG00000266173"	"STRADA"	"B4DDE3; B4DW17; hsa:92335; J3KTC9; Q5JPI2; Q7RTN6; Q7Z4K9; Q8NC31; Q8NCF1; Q9H272"	"AMP-activated protein kinase signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway"	"Energy dependent regulation of mTOR by LKB1-AMPK"	"3"	"0"	"15.8"	"15.3"	"23.3"	"14.8"	"23.5"	"21.1"	"46.4"	"57.2"	"44.2"	"62.2"	"88.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14160"	"Protein scribble homolog OS=Homo sapiens OX=9606 GN=SCRIB PE=1 SV=4"	"2"	"3"	"5"	"3"	"1630"	"174.8"	"5.07"	"1083.03"	"5.69"	"3"	"2"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"56.0"	"32.6"	"44.2"	"40.4"	"48.0"	"46.3"	"75.4"	"83.7"	"60.6"	"90.4"	"107.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96DV4"	"39S ribosomal protein L38, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL38 PE=1 SV=2"	"2"	"1"	"4"	"1"	"380"	"44.6"	"7.53"	"551.15"	"5.67"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	""	"Pf01161"	"64978"	"ENSG00000204316"	"MRPL38"	"B3KN96; hsa:64978; Q96DV4; Q96Q66; Q9P0B9"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"102.8"	"55.5"	"120.2"	"102.1"	"116.7"	"106.5"	"171.5"	"157.1"	"112.0"	"212.0"	"256.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05198"	"Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3"	"5"	"2"	"4"	"2"	"315"	"36.1"	"5.08"	"603.15"	"5.65"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf00575, Pf07541"	"1965"	"ENSG00000134001"	"EIF2S1"	"hsa:1965; P05198"	"Translation factors; Alzheimer's disease and miRNA effects; Brain-derived neurotrophic factor (BDNF) signaling pathway; Ebola virus infection in host; Nonalcoholic fatty liver disease; Measles virus infection; Unfolded protein response; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell; Alzheimer's disease"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; ABC-family proteins mediated transport; Response of EIF2AK1 (HRI) to heme deficiency; PERK regulates gene expression; Recycling of eIF2:GDP; Response of EIF2AK4 (GCN2) to amino acid deficiency"	"19"	"0"	"65.1"	"55.3"	"65.2"	"60.1"	"75.7"	"86.6"	"234.5"	"228.0"	"170.7"	"375.9"	"786.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P58546"	"Myotrophin OS=Homo sapiens OX=9606 GN=MTPN PE=1 SV=2"	"6"	"1"	"4"	"1"	"118"	"12.9"	"5.52"	"570.74"	"5.65"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity"	"Pf12796"	"136319"	"ENSG00000105887"	"MTPN"	"hsa:136319; P58546"	""	""	"0"	"0"	"159.3"	"106.0"	"170.5"	"120.1"	"146.5"	"175.7"	"226.8"	"191.4"	"182.0"	"262.6"	"448.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6I9Y2"	"THO complex subunit 7 homolog OS=Homo sapiens OX=9606 GN=THOC7 PE=1 SV=3"	"8"	"2"	"4"	"2"	"204"	"23.7"	"5.67"	"729.03"	"5.64"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf05615"	"80145"	"ENSG00000163634"	"THOC7"	"hsa:80145; Q6I9Y2; Q6P1L3; Q8WUF2; Q9H5H0"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"3"	"0"	"237.8"	"129.1"	"215.6"	"199.6"	"236.0"	"230.4"	"503.7"	"419.7"	"278.1"	"490.4"	"715.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L4I2"	"Arginine/serine-rich coiled-coil protein 2 OS=Homo sapiens OX=9606 GN=RSRC2 PE=1 SV=1"	"5"	"2"	"4"	"2"	"434"	"50.5"	"11.33"	"666.67"	"5.64"	"2"	"2"	""	""	""	"Pf15477"	"65117"	"ENSG00000111011"	"RSRC2"	"hsa:65117; Q6N040; Q6NW16; Q7L4I2; Q9H864"	""	""	"0"	"0"	"132.4"	"81.1"	"117.6"	"117.6"	"119.0"	"132.8"	"277.3"	"280.5"	"190.0"	"304.1"	"407.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P78332"	"RNA-binding protein 6 OS=Homo sapiens OX=9606 GN=RBM6 PE=1 SV=5"	"2"	"2"	"4"	"2"	"1123"	"128.6"	"6.32"	"635.28"	"5.63"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf01585, Pf17780"	"10180"	"ENSG00000004534"	"RBM6"	"B4E0G6; hsa:10180; O60549; O75524; P78332; Q86SS3"	""	""	"0"	"0"	"179.6"	"105.9"	"127.6"	"143.8"	"124.7"	"157.0"	"321.5"	"311.3"	"286.1"	"357.0"	"412.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKX7"	"Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2"	"8"	"3"	"4"	"3"	"468"	"50.1"	"7.06"	"692.78"	"5.61"	"2"	"2"	"transport"	"other membranes;nucleus"	""	"Pf00638, Pf08911"	"10762"	"ENSG00000093000"	"NUP50"	"B1AHA4; B2RB15; hsa:10762; O75644; Q8N6V5; Q9NPM9; Q9NPR6; Q9P1K5; Q9UKX7"	""	"Vpr-mediated nuclear import of PICs; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Regulation of HSF1-mediated heat shock response; HCMV Late Events; HCMV Early Events; Transcriptional regulation by small RNAs; SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Transport of Mature mRNA Derived from an Intronless Transcript; tRNA processing in the nucleus; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; snRNP Assembly; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"	"28"	"0"	"89.4"	"44.2"	"83.4"	"78.6"	"84.2"	"94.9"	"142.7"	"160.4"	"116.8"	"196.3"	"287.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49591"	"Serine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=SARS1 PE=1 SV=3"	"6"	"3"	"5"	"3"	"514"	"58.7"	"6.43"	"889.42"	"5.60"	"3"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00587, Pf02403"	"6301"	"ENSG00000031698"	"SARS1"	"B2R6Y9; hsa:6301; P49591; Q5T5C8; Q9NSE3"	"VEGFA-VEGFR2 signaling"	"Cytosolic tRNA aminoacylation; Selenocysteine synthesis"	"3"	"0"	"129.2"	"89.6"	"115.1"	"102.6"	"99.1"	"131.2"	"201.5"	"174.3"	"129.7"	"239.4"	"347.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3C6"	"Peptidyl-prolyl cis-trans isomerase-like 1 OS=Homo sapiens OX=9606 GN=PPIL1 PE=1 SV=1"	"11"	"2"	"4"	"2"	"166"	"18.2"	"7.99"	"699.38"	"5.58"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"nucleus"	"other molecular function"	"Pf00160"	"51645"	"ENSG00000137168"	"PPIL1"	"hsa:51645; O15001; Q5TDC9; Q9Y3C6"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"351.0"	"208.3"	"298.4"	"221.2"	"266.4"	"271.3"	"570.6"	"522.0"	"421.6"	"696.4"	"913.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15388"	"Mitochondrial import receptor subunit TOM20 homolog OS=Homo sapiens OX=9606 GN=TOMM20 PE=1 SV=1"	"14"	"2"	"3"	"2"	"145"	"16.3"	"8.60"	"311.76"	"5.58"	"1"	"2"	"cell organization and biogenesis;transport"	"other membranes;cytoskeleton;mitochondrion;other cell component"	"transporter activity;other molecular function"	"Pf02064"	"9804"	"ENSG00000173726"	"TOMM20"	"A8K195; hsa:9804; Q15388; Q498B3; Q6IBT4"	""	"Ub-specific processing proteases; Mitochondrial protein import; PINK1-PRKN Mediated Mitophagy"	"3"	"0"	"174.4"	"77.0"	"114.8"	"81.9"	"124.2"	"135.6"	"232.0"	"213.5"	"153.9"	"384.0"	"934.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NTJ3"	"Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2"	"1"	"2"	"3"	"2"	"1288"	"147.1"	"6.79"	"374.72"	"5.57"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463, Pf06470"	"10051"	"ENSG00000113810"	"SMC4"	"A6NLT9; D3DNL8; hsa:10051; O95752; Q8NDL4; Q9NTJ3; Q9UNT9"	"Ciliary landscape"	"Condensation of Prophase Chromosomes; Condensation of Prometaphase Chromosomes"	"3"	"0"	"80.0"	"43.5"	"81.1"	"80.2"	"94.6"	"77.5"	"316.4"	"271.2"	"173.1"	"296.9"	"367.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35998"	"26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3"	"5"	"2"	"4"	"2"	"433"	"48.6"	"5.95"	"525.27"	"5.57"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf17862"	"5701"	"ENSG00000161057"	"PSMC2"	"A4D0Q1; B7Z5E2; hsa:5701; P35998; Q3LIA5; Q9UDI3"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"Neutrophil degranulation; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Separation of Sister Chromatids; ABC-family proteins mediated transport; Defective CFTR causes cystic fibrosis; UCH proteinases; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; The role of GTSE1 in G2/M progression after G2 checkpoint; Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; MAPK6/MAPK4 signaling; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"64"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00139"	"Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3"	"3"	"2"	"3"	"2"	"706"	"79.9"	"6.68"	"306.87"	"5.57"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225"	"3796"	"ENSG00000068796"	"KIF2A"	"A5YM42; A5YM54; B4DY54; D3DW97; E9PB70; hsa:3796; O00139; Q7Z5I3; Q8N5Q7"	""	"COPI-dependent Golgi-to-ER retrograde traffic; Separation of Sister Chromatids; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Kinesins; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"9"	"0"	"83.7"	"66.2"	"74.3"	"67.6"	"81.0"	"73.6"	"201.7"	"188.5"	"115.0"	"204.8"	"290.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99733"	"Nucleosome assembly protein 1-like 4 OS=Homo sapiens OX=9606 GN=NAP1L4 PE=1 SV=1"	"8"	"4"	"6"	"3"	"375"	"42.8"	"4.69"	"1180.59"	"5.55"	"4"	"2"	"cell organization and biogenesis"	"nucleus;other cell component"	"other molecular function"	"Pf00956"	"4676"	"ENSG00000205531; ENSG00000273562"	"NAP1L4"	"B2R6J4; F5HFY4; hsa:4676; Q99733"	""	""	"0"	"0"	"43.0"	"22.4"	"35.7"	"35.0"	"36.6"	"35.4"	"99.0"	"91.5"	"75.8"	"105.6"	"108.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96F07"	"Cytoplasmic FMR1-interacting protein 2 OS=Homo sapiens OX=9606 GN=CYFIP2 PE=1 SV=2"	"2"	"2"	"4"	"2"	"1278"	"148.3"	"7.31"	"664.00"	"5.53"	"2"	"2"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf05994, Pf07159"	"26999"	"ENSG00000055163"	"CYFIP2"	"A6NLT2; D3DQJ3; hsa:26999; Q53EN5; Q96F07; Q9NTK4; Q9ULQ2; Q9UN29"	"Fragile X syndrome; Regulation of actin cytoskeleton"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RAC1 GTPase cycle; RHO GTPases Activate WASPs and WAVEs; VEGFA-VEGFR2 Pathway"	"7"	"0"	"18.6"	"16.6"	"18.8"	"24.1"	"26.5"	"22.9"	"111.9"	"92.2"	"57.3"	"116.9"	"208.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75521"	"Enoyl-CoA delta isomerase 2, mitochondrial OS=Homo sapiens OX=9606 GN=ECI2 PE=1 SV=4"	"4"	"2"	"4"	"2"	"394"	"43.6"	"9.00"	"551.72"	"5.50"	"2"	"2"	"other metabolic processes"	"cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00378, Pf00887"	"10455"	"ENSG00000198721"	"ECI2"	"hsa:10455; O75521; Q5JYK5; Q5JYK7; Q7L124; Q8N0X0; Q9BUE9; Q9H0T9; Q9NQH1; Q9NYH7; Q9UN55"	""	""	"0"	"0"	"152.4"	"103.5"	"144.1"	"153.6"	"170.8"	"198.0"	"371.7"	"402.4"	"376.2"	"576.5"	"885.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14684"	"Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3"	"6"	"3"	"5"	"3"	"758"	"84.4"	"9.76"	"875.02"	"5.49"	"3"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf05997"	"23076"	"ENSG00000160208"	"RRP1B"	"hsa:23076; Q14684; Q8TBZ4"	""	""	"0"	"0"	"79.7"	"54.8"	"70.0"	"60.0"	"69.6"	"74.4"	"337.7"	"311.7"	"275.0"	"332.1"	"434.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13576"	"Ras GTPase-activating-like protein IQGAP2 OS=Homo sapiens OX=9606 GN=IQGAP2 PE=1 SV=4"	"2"	"3"	"5"	"3"	"1575"	"180.5"	"5.64"	"861.90"	"5.49"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00307, Pf00612, Pf00616, Pf03836"	"10788"	"ENSG00000145703"	"IQGAP2"	"A8K4V1; B7Z8A4; hsa:10788; J3KR91; Q13576"	"Ciliary landscape; G13 signaling pathway"	"Neutrophil degranulation; RHO GTPases activate IQGAPs; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOG GTPase cycle"	"7"	"0"	"20.2"	"14.9"	"23.0"	"23.4"	"20.3"	"23.2"	"54.9"	"78.3"	"56.2"	"93.2"	"119.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q06787"	"Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1"	"4"	"2"	"4"	"1"	"632"	"71.1"	"7.42"	"555.12"	"5.48"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"cytoskeletal activity;translation activity;nucleic acid binding activity;other molecular function"	"Pf00013, Pf05641, Pf12235, Pf16098, Pf17904, Pf18336"	"2332"	"ENSG00000102081"	"FMR1"	"A6NNH4; D3DWT0; D3DWT1; D3DWT2; G8JL90; hsa:2332; Q06787; Q16578; Q5PQZ6; Q99054"	"Ovarian infertility; Serotonin and anxiety; Prader-Willi and Angelman syndrome; Fragile X syndrome; Disruption of postsynaptic signaling by CNV; 15q11.2 copy number variation syndrome; Primary ovarian insufficiency"	""	"7"	"1"	"96.4"	"72.2"	"81.8"	"98.1"	"99.1"	"123.2"	"276.8"	"261.4"	"201.7"	"259.0"	"343.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5D862"	"Filaggrin-2 OS=Homo sapiens OX=9606 GN=FLG2 PE=1 SV=1"	"1"	"2"	"4"	"2"	"2391"	"247.9"	"8.31"	"576.92"	"5.47"	"2"	"2"	"cell adhesion;other biological processes"	"non-structural extracellular;plasma membrane;other cell component"	"other molecular function"	"Pf01023"	"388698"	"ENSG00000143520"	"FLG2"	"hsa:388698; Q5D862; Q9H4U1"	""	"Neutrophil degranulation"	"1"	"0"	"14.1"	"8.2"	"81.6"	"14.4"	"12.5"	"13.4"	"27.0"	"20.3"	"13.2"	"31.3"	"35.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EI5"	"Transcription elongation factor A protein-like 4 OS=Homo sapiens OX=9606 GN=TCEAL4 PE=1 SV=2"	"9"	"2"	"4"	"2"	"215"	"24.6"	"5.20"	"635.50"	"5.47"	"2"	"2"	""	"nucleus"	""	"Pf04538"	"79921"	"ENSG00000133142"	"TCEAL4"	"hsa:79921; Q8WY12; Q96EI5; Q9H2H1; Q9H775"	""	""	"0"	"0"	"264.3"	"115.6"	"174.5"	"239.1"	"185.6"	"244.8"	"412.0"	"400.9"	"295.5"	"381.5"	"531.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96CS3"	"FAS-associated factor 2 OS=Homo sapiens OX=9606 GN=FAF2 PE=1 SV=2"	"4"	"2"	"4"	"2"	"445"	"52.6"	"5.62"	"657.27"	"5.46"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport"	"non-structural extracellular;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00789, Pf14555"	"23197"	"ENSG00000113194"	"FAF2"	"hsa:23197; O94963; Q8IUF2; Q96CS3; Q9BRP2; Q9BVM7"	"5q35 copy number variation"	"RHOA GTPase cycle; Neutrophil degranulation"	"3"	"0"	"111.9"	"68.7"	"93.8"	"74.8"	"86.6"	"114.5"	"115.4"	"105.8"	"87.5"	"150.6"	"243.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P36776"	"Lon protease homolog, mitochondrial OS=Homo sapiens OX=9606 GN=LONP1 PE=1 SV=2"	"3"	"3"	"5"	"3"	"959"	"106.4"	"6.39"	"1014.24"	"5.46"	"3"	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00004, Pf02190, Pf05362"	"9361"	"ENSG00000196365"	"LONP1"	"B3KPH8; D6W635; E5KMH8; F5GZ27; hsa:9361; P36776; P36777; Q8N8K8; Q9UQ95"	""	""	"0"	"0"	"72.6"	"48.0"	"62.3"	"66.3"	"59.0"	"101.8"	"121.4"	"125.8"	"94.8"	"144.5"	"170.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43818"	"U3 small nucleolar RNA-interacting protein 2 OS=Homo sapiens OX=9606 GN=RRP9 PE=1 SV=1"	"4"	"2"	"4"	"2"	"475"	"51.8"	"7.85"	"592.04"	"5.45"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00400"	"9136"	"ENSG00000114767"	"RRP9"	"B2R996; hsa:9136; O43818; Q8IZ30"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"160.6"	"122.5"	"156.9"	"124.6"	"157.0"	"138.6"	"337.1"	"337.9"	"269.6"	"426.2"	"473.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P36957"	"Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLST PE=1 SV=4"	"4"	"2"	"4"	"2"	"453"	"48.7"	"8.95"	"559.86"	"5.45"	"2"	"2"	"protein metabolism;other metabolic processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00198, Pf00364"	"1743"	"ENSG00000119689"	"DLST"	"B7Z5W8; E7ESY5; hsa:1743; P36957; Q7LDY7; Q9BQ32"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Metabolic reprogramming in colon cancer; 7q11.23 copy number variation syndrome; 1p36 copy number variation syndrome; 10q11.21q11.23 copy number variation syndrome; TCA cycle (aka Krebs or citric acid cycle)"	"Glyoxylate metabolism and glycine degradation; Lysine catabolism; Citric acid cycle (TCA cycle)"	"10"	"0"	"122.6"	"91.8"	"106.6"	"78.4"	"96.6"	"101.6"	"181.3"	"165.4"	"139.1"	"209.2"	"268.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13952"	"Nuclear transcription factor Y subunit gamma OS=Homo sapiens OX=9606 GN=NFYC PE=1 SV=3"	"7"	"3"	"5"	"3"	"458"	"50.3"	"6.10"	"837.29"	"5.44"	"3"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125"	"4802"	"ENSG00000066136"	"NFYC"	"B4DUS6; B4DW63; D3DPV9; F8VWM3; hsa:4802; Q13952; Q59GY4; Q5T6K8; Q5T6K9; Q5T6L1; Q5TZR6; Q92869; Q9HBX1; Q9NXB5; Q9UM67; Q9UML0; Q9UMT7"	""	"PPARA activates gene expression; Activation of gene expression by SREBF (SREBP); FOXO-mediated transcription of cell death genes; ATF4 activates genes in response to endoplasmic reticulum  stress; ATF6 (ATF6-alpha) activates chaperone genes"	"5"	"0"	"202.9"	"116.8"	"154.6"	"166.8"	"174.8"	"214.6"	"324.9"	"323.6"	"284.3"	"400.1"	"549.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BZF1"	"Oxysterol-binding protein-related protein 8 OS=Homo sapiens OX=9606 GN=OSBPL8 PE=1 SV=3"	"3"	"2"	"4"	"2"	"889"	"101.1"	"6.96"	"611.68"	"5.43"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00169, Pf01237"	"114882"	"ENSG00000091039"	"OSBPL8"	"A8K1T2; E9PE66; E9PE68; hsa:114882; Q52LQ3; Q68D75; Q8WXP8; Q9BZF1; Q9P277"	""	"Acyl chain remodelling of PS"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96DG6"	"Carboxymethylenebutenolidase homolog OS=Homo sapiens OX=9606 GN=CMBL PE=1 SV=1"	"10"	"3"	"5"	"3"	"245"	"28.0"	"7.18"	"953.92"	"5.42"	"3"	"2"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf01738"	"134147"	"ENSG00000164237"	"CMBL"	"D3DTC7; hsa:134147; Q8TED6; Q96DG6"	""	"Phase I - Functionalization of compounds"	"1"	"0"	"278.4"	"135.9"	"232.7"	"207.6"	"250.0"	"224.1"	"293.0"	"287.3"	"207.5"	"309.3"	"385.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P2I0"	"Cleavage and polyadenylation specificity factor subunit 2 OS=Homo sapiens OX=9606 GN=CPSF2 PE=1 SV=2"	"4"	"2"	"3"	"2"	"782"	"88.4"	"5.11"	"271.13"	"5.40"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf07521, Pf10996, Pf13299, Pf16661"	"53981"	"ENSG00000165934"	"CPSF2"	"B3KME1; hsa:53981; Q6NSJ1; Q9H3W7; Q9P2I0"	"mRNA processing"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; Transport of Mature mRNA Derived from an Intronless Transcript"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61353"	"60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2"	"18"	"3"	"5"	"3"	"136"	"15.8"	"10.56"	"973.17"	"5.40"	"3"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00467, Pf01777"	"6155"	"ENSG00000131469"	"RPL27"	"hsa:6155; P08526; P61353; Q4G0A9"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; SRP-dependent cotranslational protein targeting to membrane; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"332.6"	"213.7"	"254.4"	"198.5"	"272.8"	"279.4"	"1256.5"	"1082.1"	"702.4"	"1168.9"	"1361.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BUL8"	"Programmed cell death protein 10 OS=Homo sapiens OX=9606 GN=PDCD10 PE=1 SV=1"	"10"	"2"	"3"	"2"	"212"	"24.7"	"8.19"	"318.76"	"5.39"	"1"	"2"	"cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf06840"	"11235"	"ENSG00000114209"	"PDCD10"	"A8K515; D3DNN5; hsa:11235; O14811; Q9BUL8"	""	""	"0"	"0"	"93.9"	"62.9"	"84.5"	"95.1"	"77.2"	"107.7"	"326.9"	"311.1"	"226.2"	"344.9"	"398.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05091"	"Aldehyde dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH2 PE=1 SV=2"	"4"	"2"	"4"	"2"	"517"	"56.3"	"7.05"	"604.03"	"5.38"	"2"	"2"	"other metabolic processes;other biological processes"	"mitochondrion"	"other molecular function"	"Pf00171"	"217"	"ENSG00000111275"	"ALDH2"	"B4DW54; E7EUE5; hsa:217; P05091; Q03639; Q6IB13; Q6IV71"	"Fatty acid omega-oxidation; Ethanol effects on histone modifications; Tryptophan metabolism; Fluoroacetic acid toxicity"	"Smooth Muscle Contraction; Ethanol oxidation; Metabolism of serotonin"	"7"	"0"	"68.1"	"39.7"	"58.5"	"38.7"	"39.2"	"50.4"	"66.7"	"65.3"	"50.9"	"86.4"	"131.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06744"	"Glucose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=GPI PE=1 SV=4"	"4"	"3"	"5"	"3"	"558"	"63.1"	"8.32"	"880.65"	"5.38"	"3"	"2"	"other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00342"	"2821"	"ENSG00000105220"	"GPI"	"B4DG39; hsa:2821; P06744; Q9BRD3; Q9BSK5; Q9UHE6"	"Cori cycle; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; N-glycan biosynthesis; Disorders of fructose metabolism; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders; UDP-derived sugars synthesis in fibroblasts"	"TP53 Regulates Metabolic Genes; Glycolysis; Gluconeogenesis; Neutrophil degranulation"	"13"	"0"	"327.0"	"201.8"	"460.0"	"210.0"	"327.5"	"268.7"	"321.3"	"412.1"	"291.0"	"437.6"	"806.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49757"	"Protein numb homolog OS=Homo sapiens OX=9606 GN=NUMB PE=1 SV=2"	"2"	"1"	"3"	"1"	"651"	"70.8"	"8.51"	"343.07"	"5.38"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00640, Pf06311"	"8650"	"ENSG00000133961"	"NUMB"	"B1P2N5; B1P2N6; B1P2N7; B1P2N8; B1P2N9; B4E2B1; hsa:8650; P49757; Q6NUQ7; Q86SY1; Q8WW73; Q9UBG1; Q9UEQ4; Q9UKE8; Q9UKE9; Q9UKF0; Q9UQJ4"	"Notch signaling; VEGFA-VEGFR2 signaling; Head and neck squamous cell carcinoma; Neurogenesis regulation in the olfactory epithelium; TROP2 regulatory signaling; Notch signaling pathway"	"Recycling pathway of L1; Degradation of GLI1 by the proteasome; Hedgehog 'on' state; Activated NOTCH1 Transmits Signal to the Nucleus"	"10"	"0"	"40.9"	"22.7"	"42.2"	"35.7"	"35.4"	"42.5"	"88.9"	"121.2"	"110.5"	"163.6"	"204.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99590"	"Protein SCAF11 OS=Homo sapiens OX=9606 GN=SCAF11 PE=1 SV=2"	"1"	"2"	"3"	"2"	"1463"	"164.6"	"8.41"	"448.41"	"5.36"	"1"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	""	"9169"	"ENSG00000139218"	"SCAF11"	"A6NEU9; A6NLW5; hsa:9169; Q8IW59; Q99590"	"Apoptosis"	""	"1"	"0"	"157.7"	"84.3"	"114.3"	"121.7"	"126.8"	"163.7"	"553.4"	"538.6"	"453.9"	"880.1"	"1542.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRZ9"	"Lymphoid-specific helicase OS=Homo sapiens OX=9606 GN=HELLS PE=1 SV=1"	"3"	"3"	"4"	"3"	"838"	"97.0"	"7.93"	"627.28"	"5.36"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00176, Pf00271"	"3070"	"ENSG00000119969"	"HELLS"	"B2RB41; hsa:3070; Q3LID1; Q6I7N7; Q76H76; Q76H77; Q76H78; Q76H79; Q76H80; Q76H81; Q7Z397; Q7Z5X2; Q8N6P4; Q9H4P5; Q9NRZ9"	"Apoptosis; Apoptosis-related network due to altered Notch3 in ovarian cancer"	""	"2"	"0"	"287.3"	"141.2"	"208.2"	"229.3"	"210.6"	"261.9"	"657.4"	"609.3"	"437.9"	"709.6"	"988.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z3B4"	"Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2"	"3"	"1"	"2"	"1"	"507"	"55.4"	"7.02"	"522.18"	"5.35"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;nucleus"	"other molecular function"	"Pf13874, Pf18437"	"53371"	"ENSG00000138750"	"NUP54"	"B2RCK7; B4DT35; hsa:53371; Q7Z3B4; Q96EA7; Q9NVL5; Q9P0I1"	""	"HCMV Early Events; SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; ISG15 antiviral mechanism; NS1 Mediated Effects on Host Pathways; Transport of Mature mRNA derived from an Intron-Containing Transcript; SARS-CoV-2 activates/modulates innate and adaptive immune responses; HCMV Late Events; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; Postmitotic nuclear pore complex (NPC) reformation"	"29"	"0"	"22.5"	"14.1"	"15.4"	"12.8"	"15.3"	"16.9"	"25.3"	"25.4"	"24.6"	"35.3"	"53.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96SB8"	"Structural maintenance of chromosomes protein 6 OS=Homo sapiens OX=9606 GN=SMC6 PE=1 SV=2"	"2"	"2"	"4"	"2"	"1091"	"126.2"	"6.99"	"805.83"	"5.34"	"2"	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463"	"79677"	"ENSG00000163029"	"SMC6"	"A8K8Q6; D6W518; hsa:79677; Q05BV4; Q96SB8; Q9H0X3; Q9H6M0"	""	"SUMOylation of DNA damage response and repair proteins"	"1"	"0"	"7.6"	"13.4"	"16.3"	"14.9"	"15.9"	"16.4"	"74.7"	"63.9"	"38.0"	"66.4"	"83.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46940"	"Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1"	"1"	"2"	"3"	"2"	"1657"	"189.1"	"6.48"	"315.50"	"5.34"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00307, Pf00612, Pf00616, Pf03836"	"8826"	"ENSG00000140575"	"IQGAP1"	"A7MBM3; hsa:8826; P46940"	"VEGFA-VEGFR2 signaling; Ebola virus infection in host; Ciliary landscape; EGF/EGFR signaling pathway; Regulation of actin cytoskeleton; G13 signaling pathway"	"Signaling by BRAF and RAF1 fusions; RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHO GTPases activate IQGAPs; RAC2 GTPase cycle; RHOV GTPase cycle; Neutrophil degranulation; RHOU GTPase cycle; Nephrin family interactions; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants"	"25"	"0"	"74.2"	"46.9"	"78.7"	"52.6"	"70.6"	"72.0"	"137.6"	"123.4"	"106.6"	"179.2"	"276.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14874"	"[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial OS=Homo sapiens OX=9606 GN=BCKDK PE=1 SV=2"	"5"	"2"	"4"	"2"	"412"	"46.3"	"8.82"	"724.69"	"5.32"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"mitochondrion"	"kinase activity;other molecular function"	"Pf02518, Pf10436"	"10295"	"ENSG00000103507"	"BCKDK"	"A8MY43; hsa:10295; O14874; Q6FGL4; Q96G95; Q96IN5"	"Thiamine metabolic pathways"	"Branched-chain amino acid catabolism"	"2"	"0"	"22.8"	"18.5"	"20.1"	"18.1"	"16.9"	"21.6"	"133.9"	"110.8"	"93.0"	"112.0"	"164.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51452"	"Dual specificity protein phosphatase 3 OS=Homo sapiens OX=9606 GN=DUSP3 PE=1 SV=1"	"14"	"2"	"4"	"2"	"185"	"20.5"	"7.80"	"612.55"	"5.32"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00782"	"1845"	"ENSG00000108861"	"DUSP3"	"D3DX45; hsa:1845; P51452; Q5U0J1; Q8IYJ9"	"MAPK signaling pathway; Fragile X syndrome"	"ERKs are inactivated"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9ULP9"	"TBC1 domain family member 24 OS=Homo sapiens OX=9606 GN=TBC1D24 PE=1 SV=2"	"4"	"2"	"3"	"2"	"559"	"62.9"	"7.36"	"340.41"	"5.26"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;other cell component"	"enzyme regulator activity"	"Pf00566, Pf07534"	"57465"	"ENSG00000162065"	"TBC1D24"	"A0JNW3; B9A6M6; hsa:57465; Q2KJ08; Q9ULP9"	""	"TBC/RABGAPs"	"1"	"0"	"21.9"	"17.2"	"25.0"	"24.2"	"37.5"	"33.1"	"40.1"	"58.7"	"66.5"	"195.1"	"362.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T9A4"	"ATPase family AAA domain-containing protein 3B OS=Homo sapiens OX=9606 GN=ATAD3B PE=1 SV=1"	"3"	"2"	"3"	"2"	"648"	"72.5"	"9.20"	"295.77"	"5.25"	"1"	"2"	"cell organization and biogenesis"	"plasma membrane;other membranes;mitochondrion"	"other molecular function"	"Pf00004, Pf12037"	"83858"	"ENSG00000160072"	"ATAD3B"	"A8K3H1; hsa:83858; Q5T9A4; Q6ZRB5; Q9BUK4; Q9ULE7"	"1p36 copy number variation syndrome"	"Neutrophil degranulation"	"2"	"0"	"201.7"	"109.1"	"145.2"	"122.3"	"148.5"	"146.9"	"335.9"	"274.7"	"247.2"	"345.0"	"434.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P28331"	"NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS1 PE=1 SV=3"	"3"	"2"	"4"	"2"	"727"	"79.4"	"6.23"	"530.91"	"5.25"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00384, Pf09326, Pf10588, Pf13510"	"4719"	"ENSG00000023228; ENSG00000283447"	"NDUFS1"	"B4DIN9; B4DJA0; B4DPG1; B4DUC1; E7ENF3; hsa:4719; P28331; Q53TR8; Q8N1C4; Q8TCC9"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"62.7"	"50.0"	"51.9"	"40.9"	"51.9"	"52.0"	"86.3"	"64.3"	"49.9"	"88.7"	"127.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96PY5"	"Formin-like protein 2 OS=Homo sapiens OX=9606 GN=FMNL2 PE=1 SV=3"	"2"	"2"	"4"	"2"	"1086"	"123.2"	"7.40"	"658.71"	"5.25"	"2"	"2"	"cell organization and biogenesis;other biological processes"	"cytosol"	"cytoskeletal activity;other molecular function"	"Pf02181, Pf06367, Pf06371"	"114793"	"ENSG00000157827"	"FMNL2"	"B2RZH5; hsa:114793; Q14CC9; Q4ZG52; Q8N3E0; Q96PY5"	"Epithelial to mesenchymal transition in colorectal cancer"	"RHOC GTPase cycle; CDC42 GTPase cycle; RHO GTPases Activate Formins"	"4"	"0"	"34.7"	"14.5"	"28.4"	"20.6"	"31.5"	"19.7"	"69.9"	"57.1"	"33.2"	"69.6"	"108.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15504"	"Nucleoporin NUP42 OS=Homo sapiens OX=9606 GN=NUP42 PE=1 SV=1"	"9"	"3"	"5"	"3"	"423"	"44.8"	"9.19"	"820.47"	"5.25"	"3"	"2"	"transport"	"other membranes;cytosol;nucleus"	"other molecular function"	""	"11097"	"ENSG00000136243"	"NUP42"	"A4D143; B4DP42; hsa:11097; O15504; Q49AE7; Q9BS49"	""	"HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"28"	"0"	"71.7"	"43.0"	"66.7"	"73.9"	"77.0"	"82.6"	"171.7"	"169.4"	"130.9"	"161.2"	"203.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96J02"	"E3 ubiquitin-protein ligase Itchy homolog OS=Homo sapiens OX=9606 GN=ITCH PE=1 SV=2"	"3"	"2"	"3"	"1"	"903"	"102.7"	"6.30"	"365.22"	"5.24"	"1"	"2"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00168, Pf00397, Pf00632"	"83737"	"ENSG00000078747"	"ITCH"	"A6NEW4; B4E234; E1P5P3; F5H217; hsa:83737; O43584; Q5QP37; Q5TEL0; Q96F66; Q96J02; Q9BY75; Q9H451; Q9H4U5"	"VEGFA-VEGFR2 signaling; EGF/EGFR signaling pathway; Nonalcoholic fatty liver disease; 10q11.21q11.23 copy number variation syndrome; Notch signaling pathway"	"Antigen processing: Ubiquitination & Proteasome degradation; Degradation of GLI1 by the proteasome; Hedgehog 'on' state; RUNX1 regulates transcription of genes involved in differentiation of HSCs; SARS-CoV-1 activates/modulates innate immune responses; Negative regulators of DDX58/IFIH1 signaling; Activated NOTCH1 Transmits Signal to the Nucleus; Regulation of necroptotic cell death; NOD1/2 Signaling Pathway; Downregulation of ERBB4 signaling"	"15"	"0"	"43.2"	"23.3"	"40.6"	"46.4"	"40.0"	"48.0"	"74.9"	"73.5"	"51.6"	"91.8"	"133.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NS86"	"LanC-like protein 2 OS=Homo sapiens OX=9606 GN=LANCL2 PE=1 SV=1"	"4"	"2"	"3"	"2"	"450"	"50.8"	"7.43"	"282.58"	"5.24"	"1"	"2"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"other molecular function"	"Pf05147"	"55915"	"ENSG00000132434"	"LANCL2"	"B2R8D4; hsa:55915; Q6NSL4; Q8TCQ3; Q9BSR1; Q9NS86"	""	""	"0"	"0"	"91.4"	"62.4"	"90.4"	"90.6"	"94.7"	"118.5"	"211.6"	"239.3"	"211.8"	"294.1"	"352.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51397"	"Death-associated protein 1 OS=Homo sapiens OX=9606 GN=DAP PE=1 SV=3"	"25"	"1"	"1"	"1"	"102"	"11.2"	"9.32"	""	"5.22"	""	"1"	"other metabolic processes;stress response;signal transduction;other biological processes"	""	"other molecular function"	"Pf15228"	"1611"	"ENSG00000112977"	"DAP"	"hsa:1611; P51397; Q6FGC3; Q9BUC9"	""	""	"0"	"0"	"20.9"	"10.2"	"21.6"	"17.2"	"23.8"	"22.4"	"45.9"	"39.3"	"26.8"	"49.3"	"66.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62873"	"Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 OS=Homo sapiens OX=9606 GN=GNB1 PE=1 SV=3"	"5"	"1"	"2"	"1"	"340"	"37.4"	"6.00"	"448.49"	"5.22"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00400"	"2782"	"ENSG00000078369"	"GNB1"	"B1AJZ7; hsa:2782; P04697; P04901; P62873; Q1RMY8"	"Nicotine effect on dopaminergic neurons; Thyroid stimulating hormone (TSH) signaling pathway; Corticotropin-releasing hormone signaling pathway; Myometrial relaxation and contraction pathways; G protein signaling pathways; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Ras signaling; 1p36 copy number variation syndrome; Calcium regulation in cardiac cells; Estrogen signaling pathway"	"G alpha (q) signalling events; Thrombin signalling through proteinase activated receptors (PARs); G alpha (12/13) signalling events; Olfactory Signaling Pathway; G alpha (i) signalling events; G alpha (z) signalling events; Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1); ADP signalling through P2Y purinoceptor 12; Extra-nuclear estrogen signaling; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; Sensory perception of sweet, bitter, and umami (glutamate) taste; Activation of G protein gated Potassium channels; G-protein activation; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; G beta:gamma signalling through PI3Kgamma; Prostacyclin signalling through prostacyclin receptor; Adrenaline,noradrenaline inhibits insulin secretion; Ca2+ pathway; G beta:gamma signalling through PLC beta; ADP signalling through P2Y purinoceptor 1; Glucagon-type ligand receptors; Thromboxane signalling through TP receptor; Vasopressin regulates renal water homeostasis via Aquaporins; Presynaptic function of Kainate receptors; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; G beta:gamma signalling through BTK; G beta:gamma signalling through CDC42; Inhibition  of voltage gated Ca2+ channels via Gbeta/gamma subunits; Inactivation, recovery and regulation of the phototransduction cascade; Glucagon signaling in metabolic regulation; Activation of the phototransduction cascade"	"45"	"0"	"74.0"	"56.0"	"68.2"	"38.4"	"60.3"	"56.5"	"88.7"	"78.2"	"62.3"	"119.1"	"126.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96RL1"	"BRCA1-A complex subunit RAP80 OS=Homo sapiens OX=9606 GN=UIMC1 PE=1 SV=2"	"4"	"2"	"4"	"2"	"719"	"79.7"	"5.45"	"583.12"	"5.22"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf18282"	"51720"	"ENSG00000087206"	"UIMC1"	"A8MSA1; B3KMZ1; B4E3N2; hsa:51720; Q5XKQ1; Q7Z3W7; Q8N5B9; Q96RL1; Q9BZR1; Q9BZR5; Q9UHX7"	"5q35 copy number variation"	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; Nonhomologous End-Joining (NHEJ); Metalloprotease DUBs"	"6"	"0"	"44.8"	"18.1"	"30.6"	"45.6"	"39.2"	"48.1"	"228.8"	"209.9"	"145.0"	"182.6"	"213.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P36542"	"ATP synthase subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1C PE=1 SV=1"	"9"	"3"	"4"	"3"	"298"	"33.0"	"9.22"	"490.72"	"5.22"	"2"	"1"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf00231"	"509"	"ENSG00000165629"	"ATP5F1C"	"A8KA31; hsa:509; P36542; Q5VYP3; Q6I9V2; Q96AS8"	"Electron transport chain: OXPHOS system in mitochondria"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"3"	"0"	"207.1"	"134.2"	"165.3"	"126.5"	"160.9"	"176.3"	"238.6"	"260.0"	"195.2"	"326.2"	"406.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IXM2"	"Chromatin complexes subunit BAP18 OS=Homo sapiens OX=9606 GN=BAP18 PE=1 SV=1"	"8"	"1"	"2"	"1"	"172"	"17.9"	"7.33"	"374.67"	"5.21"	"1"	"1"	"cell organization and biogenesis"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	""	"124944"	"ENSG00000258315"	"BAP18"	"B4DIV3; C9J4G0; E9PB29; hsa:124944; Q8IXM2"	""	""	"0"	"0"	"64.2"	"39.6"	"52.0"	"46.4"	"55.6"	"53.1"	"83.9"	"80.3"	"52.3"	"96.4"	"150.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P28288"	"ATP-binding cassette sub-family D member 3 OS=Homo sapiens OX=9606 GN=ABCD3 PE=1 SV=1"	"4"	"2"	"4"	"2"	"659"	"75.4"	"9.36"	"703.21"	"5.21"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00005, Pf06472"	"5825"	"ENSG00000117528"	"ABCD3"	"D3DT46; hsa:5825; P28288; Q15271; Q6NUN5; Q96DA3; Q9H529"	"Nuclear receptors in lipid metabolism and toxicity; Fragile X syndrome"	"RHOA GTPase cycle; RHOC GTPase cycle; Class I peroxisomal membrane protein import; ABC transporters in lipid homeostasis"	"6"	"0"	"118.9"	"69.0"	"77.0"	"65.4"	"83.2"	"92.3"	"158.1"	"116.1"	"107.6"	"179.6"	"232.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TAT6"	"Nuclear protein localization protein 4 homolog OS=Homo sapiens OX=9606 GN=NPLOC4 PE=1 SV=3"	"3"	"1"	"2"	"1"	"608"	"68.1"	"6.38"	"550.00"	"5.21"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf05020, Pf05021, Pf11543"	"55666"	"ENSG00000182446"	"NPLOC4"	"hsa:55666; Q8N3J1; Q8TAT6; Q9H8V2; Q9H964; Q9NWR5; Q9P229"	""	"Neddylation; KEAP1-NFE2L2 pathway; Translesion Synthesis by POLH"	"3"	"0"	"53.1"	"37.0"	"46.5"	"44.1"	"45.8"	"58.5"	"84.8"	"91.0"	"70.9"	"94.2"	"101.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IV48"	"3'-5' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=ERI1 PE=1 SV=3"	"2"	"1"	"4"	"1"	"349"	"40.0"	"6.70"	"593.75"	"5.18"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00929, Pf02037"	"90459"	"ENSG00000104626"	"ERI1"	"A8K4U7; hsa:90459; Q8IV48; Q9NSX3"	"exRNA mechanism of action and biogenesis; 8p23.1 copy number variation syndrome; 4p16.3 copy number variation"	"Major pathway of rRNA processing in the nucleolus and cytosol"	"4"	"0"	"21.6"	"28.5"	"28.2"	"29.8"	"33.2"	"36.8"	"115.6"	"108.5"	"116.5"	"249.8"	"405.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H6S0"	"3'-5' RNA helicase YTHDC2 OS=Homo sapiens OX=9606 GN=YTHDC2 PE=1 SV=2"	"1"	"2"	"4"	"2"	"1430"	"160.1"	"8.40"	"535.51"	"5.18"	"2"	"2"	"cell cycle OR cell proliferation;other biological processes"	"ER/Golgi;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf01424, Pf04146, Pf04408, Pf07717"	"64848"	"ENSG00000047188"	"YTHDC2"	"B2RP66; hsa:64848; Q9H6S0"	""	""	"0"	"0"	"11.8"	"4.0"	"9.6"	"5.4"	"4.0"	"9.8"	"15.0"	"16.0"	"11.4"	"16.5"	"25.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H6R4"	"Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2"	"2"	"2"	"4"	"2"	"1146"	"127.5"	"7.64"	"611.68"	"5.18"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"mitochondrion;nucleus;other cell component"	""	"Pf03813, Pf17403, Pf17404, Pf17405, Pf17406, Pf17407"	"65083"	"ENSG00000165271"	"NOL6"	"hsa:65083; Q5T5M3; Q5T5M4; Q7L4G6; Q8N6I0; Q8TEY9; Q8TEZ0; Q8TEZ1; Q9H675; Q9H6R4"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"48.7"	"32.0"	"50.1"	"42.3"	"46.7"	"47.1"	"87.3"	"84.2"	"78.1"	"133.0"	"170.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51970"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 OS=Homo sapiens OX=9606 GN=NDUFA8 PE=1 SV=3"	"15"	"3"	"6"	"3"	"172"	"20.1"	"7.65"	"1129.41"	"5.17"	"3"	"2"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf06747"	"4702"	"ENSG00000119421"	"NDUFA8"	"B1AM93; hsa:4702; P51970; Q9Y6N0"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"640.6"	"306.5"	"389.3"	"464.6"	"437.6"	"620.1"	"1460.7"	"1345.8"	"1024.2"	"1630.1"	"2442.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13861"	"cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2"	"5"	"2"	"3"	"2"	"404"	"45.5"	"5.07"	"250.95"	"5.15"	"1"	"2"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00027, Pf02197"	"5576"	"ENSG00000114302"	"PRKAR2A"	"hsa:5576; P13861; Q16823; Q9BUB1"	"Myometrial relaxation and contraction pathways; G protein signaling pathways; Lipid metabolism pathway; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; GDNF signaling; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"GPER1 signaling; FCGR3A-mediated IL10 synthesis; ADORA2B mediated anti-inflammatory cytokines production; Factors involved in megakaryocyte development and platelet production; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Vasopressin regulates renal water homeostasis via Aquaporins; PKA activation; PKA activation in glucagon signalling; Hedgehog 'off' state; DARPP-32 events; CREB1 phosphorylation through the activation of Adenylate Cyclase; ROBO receptors bind AKAP5"	"20"	"0"	"44.3"	"22.7"	"20.9"	"26.1"	"26.5"	"41.6"	"42.9"	"34.0"	"30.4"	"59.0"	"95.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30048"	"Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3"	"11"	"3"	"5"	"3"	"256"	"27.7"	"7.78"	"875.64"	"5.13"	"3"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00578, Pf10417"	"10935"	"ENSG00000165672"	"PRDX3"	"B2R7Z0; D3DRC9; E9PH29; hsa:10935; P30048; P35690; Q0D2H1; Q13776; Q5T5V2; Q96HK4"	"Selenium micronutrient network"	"Detoxification of Reactive Oxygen Species"	"2"	"0"	"483.6"	"215.0"	"305.8"	"239.5"	"247.1"	"343.9"	"396.9"	"334.9"	"246.5"	"438.2"	"830.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16643"	"Drebrin OS=Homo sapiens OX=9606 GN=DBN1 PE=1 SV=4"	"1"	"1"	"4"	"1"	"649"	"71.4"	"4.45"	"675.94"	"5.12"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00241"	"1627"	"ENSG00000113758"	"DBN1"	"A8MV58; B2RBG0; hsa:1627; Q16643; Q9UFZ5"	"5q35 copy number variation"	"RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle; RHOH GTPase cycle; RHOD GTPase cycle"	"5"	"0"	"407.4"	"221.3"	"328.2"	"303.5"	"332.7"	"351.7"	"530.7"	"400.4"	"239.0"	"588.1"	"1098.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43678"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 OS=Homo sapiens OX=9606 GN=NDUFA2 PE=1 SV=3"	"21"	"1"	"1"	"1"	"99"	"10.9"	"9.57"	""	"5.12"	""	"1"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes"	"other membranes;mitochondrion"	"transporter activity"	"Pf05047"	"4695"	"ENSG00000131495"	"NDUFA2"	"D6RJD6; hsa:4695; O43678; Q6IAY8"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"13.6"	"14.0"	"18.2"	"14.9"	"7.0"	"18.7"	"28.4"	"27.3"	"19.4"	"33.6"	"39.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P28074"	"Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3"	"5"	"1"	"2"	"1"	"263"	"28.5"	"6.92"	"604.60"	"5.12"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00227"	"5693"	"ENSG00000100804"	"PSMB5"	"B2R4N9; B4DUM9; D3DS43; E9PAV2; hsa:5693; P28074; Q16242; Q6PEW2; Q7Z3B5; Q86T01; Q9TNN9"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Regulation of expression of SLITs and ROBOs; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; SCF(Skp2)-mediated degradation of p27/p21; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"62"	"0"	"10.8"	"14.2"	"19.7"	"13.6"	"15.1"	"14.6"	"32.2"	"32.0"	"17.3"	"31.2"	"43.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52756"	"RNA-binding protein 5 OS=Homo sapiens OX=9606 GN=RBM5 PE=1 SV=2"	"2"	"2"	"4"	"1"	"815"	"92.1"	"6.28"	"657.03"	"5.12"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00641, Pf01585, Pf17780"	"10181"	"ENSG00000003756"	"RBM5"	"B2RA45; B4DM16; B4DMF9; B4DZ63; hsa:10181; P52756; Q93021; Q9BU14; Q9HDA6; Q9UKY8; Q9UL24"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"25.2"	"18.8"	"22.2"	"23.7"	"24.0"	"26.6"	"46.5"	"37.9"	"30.5"	"56.6"	"71.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43920"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 OS=Homo sapiens OX=9606 GN=NDUFS5 PE=1 SV=3"	"19"	"2"	"3"	"2"	"106"	"12.5"	"9.14"	"785.68"	"5.11"	"2"	"1"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf10200"	"4725"	"ENSG00000168653"	"NDUFS5"	"hsa:4725; O43920"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"85.5"	"51.4"	"54.6"	"64.5"	"62.0"	"67.8"	"442.2"	"474.5"	"372.0"	"455.1"	"373.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07919"	"Cytochrome b-c1 complex subunit 6, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRH PE=1 SV=2"	"34"	"3"	"6"	"3"	"91"	"10.7"	"4.44"	"1053.95"	"5.11"	"3"	"2"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf02320"	"7388"	"ENSG00000173660"	"UQCRH"	"B2R4V9; D3DQ18; hsa:7388; P07919; Q5TDF6; Q6LDB8; Q9BQ91"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex III assembly"	"Respiratory electron transport"	"4"	"0"	"662.1"	"459.1"	"577.8"	"600.3"	"641.0"	"668.3"	"1021.8"	"911.2"	"726.5"	"1026.5"	"1352.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63218"	"Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 OS=Homo sapiens OX=9606 GN=GNG5 PE=1 SV=3"	"24"	"2"	"3"	"2"	"68"	"7.3"	"9.85"	"373.72"	"5.09"	"1"	"2"	"signal transduction"	"plasma membrane;other membranes"	"other molecular function"	"Pf00631"	"2787"	"ENSG00000174021"	"GNG5"	"B2R5A0; hsa:2787; P30670; P63218; Q5VX54; Q61015"	"Myometrial relaxation and contraction pathways; G protein signaling pathways; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Ras signaling; Calcium regulation in cardiac cells"	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; G alpha (12/13) signalling events; G alpha (q) signalling events; G alpha (i) signalling events; G alpha (z) signalling events; ADP signalling through P2Y purinoceptor 12; Extra-nuclear estrogen signaling; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; Thrombin signalling through proteinase activated receptors (PARs); Activation of G protein gated Potassium channels; G-protein activation; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; G beta:gamma signalling through PI3Kgamma; Prostacyclin signalling through prostacyclin receptor; Adrenaline,noradrenaline inhibits insulin secretion; Ca2+ pathway; G beta:gamma signalling through PLC beta; ADP signalling through P2Y purinoceptor 1; Glucagon-type ligand receptors; Thromboxane signalling through TP receptor; Vasopressin regulates renal water homeostasis via Aquaporins; Presynaptic function of Kainate receptors; G beta:gamma signalling through BTK; G beta:gamma signalling through CDC42; Inhibition  of voltage gated Ca2+ channels via Gbeta/gamma subunits; Glucagon signaling in metabolic regulation"	"35"	"0"	"440.0"	"260.7"	"355.2"	"209.5"	"337.3"	"316.4"	"390.1"	"311.2"	"239.7"	"504.3"	"635.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P29992"	"Guanine nucleotide-binding protein subunit alpha-11 OS=Homo sapiens OX=9606 GN=GNA11 PE=1 SV=2"	"6"	"2"	"3"	"2"	"359"	"42.1"	"5.69"	"307.28"	"5.08"	"1"	"2"	"cell-cell signaling;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00503"	"2767"	"ENSG00000088256"	"GNA11"	"hsa:2767; O15109; P29992; Q14350; Q6IB00"	"Corticotropin-releasing hormone signaling pathway; G protein signaling pathways; GPR40 pathway; Hippo signaling regulation pathways; PKC-gamma calcium signaling pathway in ataxia; Orexin receptor pathway; Calcium regulation in cardiac cells"	"G alpha (q) signalling events; Thrombin signalling through proteinase activated receptors (PARs); G-protein activation; ADP signalling through P2Y purinoceptor 1; Thromboxane signalling through TP receptor; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion; PLC beta mediated events; Acetylcholine regulates insulin secretion"	"16"	"0"	"62.9"	"44.1"	"53.3"	"42.1"	"57.8"	"70.1"	"91.5"	"81.6"	"57.3"	"111.5"	"131.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9ULC4"	"Malignant T-cell-amplified sequence 1 OS=Homo sapiens OX=9606 GN=MCTS1 PE=1 SV=1"	"17"	"2"	"4"	"2"	"181"	"20.5"	"8.82"	"514.73"	"5.08"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"other cell component"	"nucleic acid binding activity"	"Pf01472, Pf17832"	"28985"	"ENSG00000232119; ENSG00000288295"	"MCTS1"	"B4DGY2; hsa:28985; Q502X6; Q9ULC4"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92979"	"Ribosomal RNA small subunit methyltransferase NEP1 OS=Homo sapiens OX=9606 GN=EMG1 PE=1 SV=4"	"8"	"2"	"4"	"2"	"244"	"26.7"	"9.17"	"636.17"	"5.08"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03587"	"10436"	"ENSG00000126749"	"EMG1"	"hsa:10436; O00675; O00726; Q92979"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"70.2"	"38.4"	"72.5"	"64.7"	"74.3"	"84.1"	"178.2"	"176.2"	"128.3"	"218.7"	"317.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75608"	"Acyl-protein thioesterase 1 OS=Homo sapiens OX=9606 GN=LYPLA1 PE=1 SV=1"	"7"	"2"	"4"	"2"	"230"	"24.7"	"6.77"	"620.85"	"5.07"	"2"	"2"	"protein metabolism;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf02230"	"10434"	"ENSG00000120992"	"LYPLA1"	"hsa:10434; O43202; O75608; Q9UQF9"	""	"RAS processing; eNOS activation"	"2"	"0"	"413.4"	"172.0"	"255.6"	"265.0"	"270.9"	"351.8"	"368.2"	"340.8"	"274.3"	"367.8"	"590.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49841"	"Glycogen synthase kinase-3 beta OS=Homo sapiens OX=9606 GN=GSK3B PE=1 SV=2"	"5"	"1"	"1"	"1"	"420"	"46.7"	"8.78"	""	"5.07"	""	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00069"	"2932"	"ENSG00000082701"	"GSK3B"	"D3DN89; hsa:2932; P49841; Q9BWH3; Q9UL47"	"IL-5 signaling pathway; Androgen receptor signaling pathway; Energy metabolism; MicroRNAs in cardiomyocyte hypertrophy; Cell cycle; Leptin signaling pathway; TNF-related weak inducer of apoptosis (TWEAK) signaling pathway; Prolactin signaling pathway; Microtubule cytoskeleton regulation; IL-7 signaling pathway; Alzheimer's disease and miRNA effects; Neural crest differentiation; IL-17 signaling pathway; B cell receptor signaling pathway; Corticotropin-releasing hormone signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Cardiac progenitor differentiation; T cell receptor and co-stimulatory signaling; Cardiac hypertrophic response; Focal adhesion; Copper homeostasis; Melatonin metabolism and effects; Wnt signaling pathway; IL6 signaling pathway; Wnt/beta-catenin signaling pathway in leukemia; Regulation of Wnt / B-catenin signaling by small molecule compounds; Physico-chemical features and toxicity-associated pathways; PI3K-AKT-mTOR signaling pathway and therapeutic opportunities in prostate cancer; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; Regulation of apoptosis by parathyroid hormone-related protein; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Chemokine signaling pathway; Embryonic stem cell pluripotency pathways; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Wnt signaling pathway and pluripotency; PI3K/AKT/mTOR - vitamin D3 signaling; Endometrial cancer; PI3K-Akt signaling pathway; Chromosomal and microsatellite instability in colorectal cancer ; Epithelial to mesenchymal transition in colorectal cancer; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; Acute viral myocarditis; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; NRF2-ARE regulation; Nonalcoholic fatty liver disease; Synaptic signaling pathways associated with autism spectrum disorder; Gastrin signaling pathway; Thyroid hormones production and peripheral downstream signaling effects; IL-18 signaling pathway; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; Influence of laminopathies on Wnt signaling; MAP3K1 role in promoting and blocking gonadal determination; Overlap between signal transduction pathways contributing to LMNA laminopathies; Glycogen synthesis and degradation; Pleural mesothelioma; CCL18 signaling pathway; Alzheimer's disease; GDNF signaling; DYRK1A involvement regarding cell proliferation in brain development; Neurogenesis regulation in the olfactory epithelium; Sildenafil treatment; A network map of Macrophage-stimulating protein (MSP) signaling; Notch signaling pathway; ErbB signaling pathway; DNA damage response (only ATM dependent)"	"Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Ubiquitin-dependent degradation of Cyclin D; Regulation of RUNX2 expression and activity; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Regulation of HSF1-mediated heat shock response; Constitutive Signaling by AKT1 E17K in Cancer; B-WICH complex positively regulates rRNA expression; CRMPs in Sema3A signaling; Disassembly of the destruction complex and recruitment of AXIN to the membrane; AKT phosphorylates targets in the cytosol; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; APC truncation mutants have impaired AXIN binding; AXIN missense mutants destabilize the destruction complex; Truncations of AMER1 destabilize the destruction complex; Maturation of nucleoprotein; Maturation of nucleoprotein"	"93"	"0"	"5.7"	"3.1"	"7.0"	"4.1"	"8.3"	"6.6"	"29.1"	"29.6"	"22.5"	"32.0"	"30.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6X4"	"Soluble lamin-associated protein of 75 kDa OS=Homo sapiens OX=9606 GN=FAM169A PE=1 SV=2"	"4"	"2"	"4"	"2"	"670"	"74.9"	"4.60"	"696.90"	"5.07"	"2"	"2"	""	"other membranes;nucleus"	""	""	"26049"	"ENSG00000198780"	"FAM169A"	"A8K1T9; hsa:26049; Q6MZT0; Q9H989; Q9Y6X4"	""	"RHOF GTPase cycle"	"1"	"0"	"40.4"	"23.6"	"49.4"	"37.9"	"31.9"	"44.2"	"47.8"	"50.3"	"39.4"	"53.3"	"89.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31151"	"Protein S100-A7 OS=Homo sapiens OX=9606 GN=S100A7 PE=1 SV=4"	"22"	"2"	"4"	"2"	"101"	"11.5"	"6.77"	"777.13"	"5.07"	"2"	"2"	"stress response;developmental processes;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01023"	"6278"	"ENSG00000143556"	"S100A7"	"hsa:6278; P31151; Q5SY67; Q6FGE3; Q9H1E2"	""	"Neutrophil degranulation; Metal sequestration by antimicrobial proteins"	"2"	"0"	"37.2"	"23.3"	"45.4"	"33.5"	"39.4"	"30.5"	"153.0"	"140.7"	"116.5"	"168.8"	"205.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75874"	"Isocitrate dehydrogenase [NADP] cytoplasmic OS=Homo sapiens OX=9606 GN=IDH1 PE=1 SV=2"	"8"	"3"	"5"	"3"	"414"	"46.6"	"7.01"	"995.22"	"5.06"	"3"	"2"	"other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00180"	"3417"	"ENSG00000138413"	"IDH1"	"hsa:3417; O75874; Q567U4; Q6FHQ6; Q7Z3V0; Q93090; Q9NTJ9; Q9UKW8"	"Glutathione metabolism; TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism"	"Neutrophil degranulation; Peroxisomal protein import; Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate; NADPH regeneration; NFE2L2 regulating TCA cycle genes"	"8"	"0"	"75.4"	"47.4"	"82.4"	"69.8"	"86.1"	"79.0"	"121.4"	"108.9"	"80.7"	"130.5"	"161.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z2W4"	"Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3"	"2"	"2"	"3"	"2"	"902"	"101.4"	"8.40"	"236.32"	"5.06"	"1"	"2"	"stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00644, Pf02825, Pf18606, Pf18633"	"56829"	"ENSG00000105939"	"ZC3HAV1"	"A4D1R2; A4D1S4; hsa:56829; Q7Z2W4; Q8IW57; Q8TAJ3; Q96N79; Q9H8R9; Q9P0Y7"	""	"Signaling by BRAF and RAF1 fusions"	"1"	"0"	"23.3"	"11.9"	"14.3"	"13.2"	"19.1"	"11.5"	"46.2"	"41.4"	"40.5"	"38.7"	"51.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P17480"	"Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1"	"2"	"1"	"2"	"1"	"764"	"89.4"	"5.81"	"557.43"	"5.05"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00505, Pf09011, Pf14887"	"7343"	"ENSG00000108312"	"UBTF"	"A8K6R8; hsa:7343; P17480"	"Ectoderm differentiation"	"NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; RNA Polymerase I Promoter Opening"	"6"	"0"	"10.9"	"6.4"	"8.2"	"13.5"	"9.6"	"13.3"	"95.9"	"101.3"	"110.1"	"227.8"	"309.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7RTP6"	"[F-actin]-monooxygenase MICAL3 OS=Homo sapiens OX=9606 GN=MICAL3 PE=1 SV=2"	"1"	"2"	"2"	"2"	"2002"	"224.2"	"5.55"	""	"5.05"	""	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00412, Pf01494, Pf12130"	"57553"	"ENSG00000243156"	"MICAL3"	"B2RXJ5; E9PEF0; hsa:57553; O94909; Q5U4P4; Q6ICK4; Q7RTP6; Q96DF2; Q9P2I3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96HP4"	"Oxidoreductase NAD-binding domain-containing protein 1 OS=Homo sapiens OX=9606 GN=OXNAD1 PE=1 SV=1"	"10"	"2"	"3"	"2"	"312"	"34.8"	"8.37"	"375.16"	"5.04"	"1"	"2"	""	""	"other molecular function"	"Pf00175"	"92106"	"ENSG00000154814"	"OXNAD1"	"hsa:92106; Q2HYC7; Q59FA4; Q96HP4"	""	""	"0"	"0"	"8.6"	"5.0"	"8.3"	"7.2"	"10.5"	"7.5"	"12.9"	"13.2"	"11.7"	"25.9"	"41.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99575"	"Ribonucleases P/MRP protein subunit POP1 OS=Homo sapiens OX=9606 GN=POP1 PE=1 SV=2"	"3"	"3"	"4"	"3"	"1024"	"114.6"	"9.22"	"606.97"	"5.04"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06978, Pf08170"	"10940"	"ENSG00000104356"	"POP1"	"A8K5W9; hsa:10940; Q15037; Q99575"	""	"tRNA processing in the nucleus"	"1"	"0"	"315.9"	"79.1"	"280.5"	"275.4"	"356.8"	"193.4"	"468.9"	"289.4"	"148.2"	"340.1"	"761.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRY2"	"SOSS complex subunit C OS=Homo sapiens OX=9606 GN=INIP PE=1 SV=1"	"9"	"1"	"3"	"1"	"104"	"11.4"	"9.25"	"371.94"	"5.03"	"1"	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	""	"Pf15925"	"58493"	"ENSG00000148153"	"INIP"	"hsa:58493; Q5VWJ7; Q96E04; Q9NRY2; Q9P090"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5V0"	"Zinc finger protein 706 OS=Homo sapiens OX=9606 GN=ZNF706 PE=1 SV=1"	"24"	"2"	"3"	"2"	"76"	"8.5"	"10.01"	"273.51"	"5.03"	"1"	"2"	"other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf04419, Pf12874"	"51123"	"ENSG00000120963"	"ZNF706"	"A8K362; hsa:51123; Q9Y5V0"	""	"Generic Transcription Pathway"	"1"	"0"	"236.1"	"146.0"	"211.5"	"229.2"	"247.5"	"219.4"	"986.3"	"839.2"	"648.4"	"1242.6"	"2005.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5J9"	"Mitochondrial import inner membrane translocase subunit Tim8 B OS=Homo sapiens OX=9606 GN=TIMM8B PE=1 SV=1"	"13"	"1"	"4"	"1"	"83"	"9.3"	"5.12"	"626.58"	"5.02"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf02953"	"26521"	"ENSG00000150779"	"TIMM8B"	"B0YJA5; hsa:26521; Q3KQS9; Q9UN04; Q9Y5J9"	""	"Mitochondrial protein import"	"1"	"0"	"29.5"	"23.3"	"24.4"	"27.8"	"24.7"	"26.3"	"73.2"	"66.1"	"63.3"	"92.1"	"215.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NFJ9"	"Bardet-Biedl syndrome 1 protein OS=Homo sapiens OX=9606 GN=BBS1 PE=1 SV=1"	"3"	"1"	"2"	"1"	"593"	"65.0"	"7.93"	"577.80"	"5.01"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf14779"	"582"	"ENSG00000174483"	"BBS1"	"hsa:582; Q32MM9; Q32MN0; Q8NFJ9; Q96SN4"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies; Bardet-Biedl syndrome"	"BBSome-mediated cargo-targeting to cilium"	"6"	"0"	"7.6"	"6.0"	"9.9"	"10.8"	"12.9"	"10.3"	"15.4"	"27.7"	"19.8"	"55.8"	"71.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04632"	"Calpain small subunit 1 OS=Homo sapiens OX=9606 GN=CAPNS1 PE=1 SV=1"	"14"	"3"	"5"	"3"	"268"	"28.3"	"5.20"	"539.47"	"5.01"	"2"	"3"	"protein metabolism;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	""	"826"	"ENSG00000126247"	"CAPNS1"	"A8K0P1; hsa:826; P04632; Q8WTX3; Q96EW0"	"Integrin-mediated cell adhesion"	"Degradation of the extracellular matrix; Formation of the cornified envelope; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"	"4"	"0"	"234.1"	"129.6"	"246.2"	"191.6"	"210.1"	"254.4"	"351.8"	"329.6"	"236.5"	"360.7"	"544.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96M86"	"Dynein heavy chain domain-containing protein 1 OS=Homo sapiens OX=9606 GN=DNHD1 PE=2 SV=2"	"0"	"2"	"2"	"1"	"4753"	"533.3"	"6.71"	""	"5.00"	""	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton"	"cytoskeletal activity;other molecular function"	"Pf03028, Pf08393, Pf12774, Pf12775, Pf12777, Pf12780, Pf17852, Pf18199"	"144132"	"ENSG00000179532"	"DNHD1"	"hsa:144132; Q2NKK8; Q6UWI9; Q8NAA2; Q8TEE6; Q96M86; Q9NSZ9"	""	""	"0"	"0"	"71.8"	"39.3"	"70.0"	"64.5"	"73.5"	"71.0"	"150.3"	"119.0"	"71.0"	"147.2"	"205.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25789"	"Proteasome subunit alpha type-4 OS=Homo sapiens OX=9606 GN=PSMA4 PE=1 SV=1"	"7"	"2"	"4"	"2"	"261"	"29.5"	"7.72"	"624.58"	"4.97"	"2"	"2"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf00227, Pf10584"	"5685"	"ENSG00000041357"	"PSMA4"	"D3DW86; hsa:5685; P25789; Q53XP2; Q567Q5; Q8TBD1"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Exercise-induced circadian regulation; Alzheimer's disease"	"MAPK6/MAPK4 signaling; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"63"	"0"	"171.8"	"90.3"	"133.8"	"126.9"	"147.6"	"168.5"	"290.2"	"251.3"	"191.7"	"361.5"	"587.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P16220"	"Cyclic AMP-responsive element-binding protein 1 OS=Homo sapiens OX=9606 GN=CREB1 PE=1 SV=2"	"5"	"2"	"3"	"2"	"341"	"36.7"	"5.57"	"309.51"	"4.96"	"1"	"2"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00170, Pf02173"	"100351999; 100477711; 100586647; 100675162; 100974672; 101010524; 101356881; 101383024; 101608568; 101964691; 102141699; 102246867; 102428529; 102531048; 102748542; 103217717; 103744440; 104680220; 105468005; 105517357; 105549382; 105580103; 105864304; 106967098; 108540349; 109691946; 1385; 459901; 607922; 708717"	"ENSAMEG00000015152; ENSCAFG00000013510; ENSCAFG00030010510; ENSCAFG00040025786; ENSCAFG00845022020; ENSCANG00000030079; ENSCATG00000037133; ENSCCNG00000003127; ENSCSAG00000010111; ENSFCAG00000008220; ENSGGOG00000024394; ENSJJAG00000013846; ENSLAFG00000013257; ENSLCNG00005016477; ENSMFAG00000039629; ENSMICG00000009731; ENSMLEG00000033904; ENSMLUG00000016119; ENSMMMG00000014914; ENSMMUG00000022601; ENSMNEG00000030274; ENSNGAG00000018967; ENSNLEG00000007124; ENSOCUG00000005427; ENSPANG00000009083; ENSPLOG00000007090; ENSPPAG00000042817; ENSPPYG00000013115; ENSPTIG00000011848; ENSPTRG00000043959; ENSRBIG00000040701; ENSRFEG00010020193; ENSRROG00000035316; ENSSDAG00000020160; ENSSSCG00005034714; ENSSSCG00015008370; ENSSSCG00025020324; ENSSSCG00030035186; ENSSSCG00035079382; ENSSSCG00040036512; ENSSSCG00045023175; ENSSSCG00050037141; ENSSSCG00055008554; ENSSSCG00060058264; ENSSSCG00065052126; ENSSSCG00070020566; ENSSSUG00005001816; ENSSTOG00000016482; ENSSVLG00005003093; ENSTGEG00000004249; ENSUAMG00000018783; ENSUMAG00000022656; ENSUPAG00010007984; ENSVVUG00000011892"	"Creb1; CREB1; LOC101356881"	"A0A024R401; A0A096MS95; A0A0D9RCK8; A0A286ZWB0; A0A2I2YCF6; A0A2J8N5U5; A0A2J8WUF2; A0A2K5I9K2; A0A2K5MQP0; A0A2K5X536; A0A2K5X539; A0A2K5YUX5; A0A2K6BKD0; A0A2K6MDT5; A0A2K6Q2B5; A0A2R9CPF8; A0A2U3WAS2; A0A2U3XPQ5; A0A2Y9R2V7; A0A384BST9; A0A3Q7QRU5; A0A3Q7SQX8; A0A452RWS8; A0A4X1V0B9; A0A5E4AFY5; A0A5N4E668; A0A667HEB5; A0A671G6M8; A0A673T0V2; A0A6D2VSK7; A0A6D2WEQ2; A0A6G1BFF3; A0A6I9IA29; A0A6J1YUG6; A0A6J2CMJ0; A0A6J2LK21; A0A6P6GX89; A0A7J7WGC8; A0A7J7XTS6; A0A7J8FQY6; A0A811ZBK8; A0A8B7V7Z4; A0A8B8T0S6; A0A8C0N7M6; A0A8C5KHE0; A0A8C5V357; A0A8C6EUY0; A0A8C6RKM3; A0A8C8WVH7; A0A8C9JRV6; A0A8C9Q947; A0A8D2AN63; A0A8D2EE05; A0A8D2H908; A0A8I3S2U7; A0A8J8XE04; A0A8J8XJ71; A0A8M1M6Z7; aju:106967098; aml:100477711; cang:105517357; caty:105580103; ccan:109691946; cfa:607922; cfr:102508765; csab:103217717; D2H8G8; F7AUB4; G1PTV7; G1R662; G1SNW9; G3TAZ1; G7N8R8; H2P8F2; H2R2Y2; I3MRM5; lav:100675162; lww:102748542; M3W964; mcc:708717; mcf:102141699; mleu:105549382; mlf:102428529; mmur:105864304; myb:102246867; ngi:103744440; ocu:100351999; oro:101383024; pdic:114495167; ptr:459901; Q5U0J5; rbb:108540349; rro:104680220; S7N6N9; tmu:101356881; umr:103659802; vpc:102531048; vvp:112922611; zca:113919503"	"IL-2 signaling pathway; EGFR1 signaling pathway; Adipogenesis; Androgen receptor signaling pathway; p38 MAPK signaling pathway; G1 to S cell cycle control; Androgen receptor signaling pathway; miRNA regulation of DNA damage response; Energy metabolism; miRNAs involved in DNA damage response; Folate-alcohol and cancer pathway hypotheses; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Follicle stimulating hormone (FSH) signaling pathway; B cell receptor signaling pathway; Interleukin-11 signaling pathway; Corticotropin-releasing hormone signaling pathway; Adipogenesis; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; ATM signaling pathway; Myometrial relaxation and contraction pathways; VEGFA-VEGFR2 signaling; Mitochondrial gene expression; p38 MAPK signaling pathway; EGF/EGFR signaling pathway; G1 to S cell cycle control; Gastrin signaling pathway; CAMKK2 pathway; Galanin receptor pathway; Neuroinflammation and glutamatergic signaling; GDNF signaling; Interferon type I signaling pathways; T-cell receptor signaling pathway; Sudden infant death syndrome (SIDS) susceptibility pathways; DNA damage response; Estrogen signaling pathway; Serotonin HTR1 group and FOS pathway; Serotonin receptor 4/6/7 and NR3C signaling; EGFR1 signaling pathway; Adipogenesis; Androgen receptor signaling pathway; p38 MAPK signaling pathway; G1 to S cell cycle control"	"NCAM signaling for neurite out-growth; CREB phosphorylation; CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling; Gastrin-CREB signalling pathway via PKC and MAPK; NGF-stimulated transcription"	"49"	"0"	"256.9"	"140.9"	"215.5"	"253.8"	"242.2"	"296.9"	"558.8"	"498.8"	"321.6"	"551.0"	"950.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P57076"	"Cilia- and flagella-associated protein 298 OS=Homo sapiens OX=9606 GN=CFAP298 PE=1 SV=1"	"6"	"2"	"4"	"2"	"290"	"33.2"	"7.44"	"544.76"	"4.95"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	""	"Pf11069"	"56683"	"ENSG00000159079"	"CFAP298"	"hsa:56683; P57076; Q53FH0"	"Ciliopathies"	""	"1"	"0"	"150.5"	"80.5"	"90.1"	"135.1"	"102.8"	"158.3"	"328.3"	"316.0"	"257.1"	"419.0"	"571.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y296"	"Trafficking protein particle complex subunit 4 OS=Homo sapiens OX=9606 GN=TRAPPC4 PE=1 SV=1"	"9"	"2"	"4"	"2"	"219"	"24.3"	"6.21"	"575.51"	"4.95"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf04099"	"51399"	"ENSG00000196655; ENSG00000280495"	"TRAPPC4"	"A8K3A5; B4DME1; hsa:51399; Q9Y296"	""	"RAB GEFs exchange GTP for GDP on RABs; COPII-mediated vesicle transport; Syndecan interactions"	"3"	"0"	"46.7"	"40.2"	"54.6"	"54.6"	"68.1"	"66.5"	"68.5"	"66.4"	"61.9"	"85.9"	"109.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15019"	"Septin-2 OS=Homo sapiens OX=9606 GN=SEPTIN2 PE=1 SV=1"	"4"	"2"	"4"	"2"	"361"	"41.5"	"6.60"	"676.15"	"4.95"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00735"	"4735"	"ENSG00000168385"	"SEPTIN2"	"B4DGE8; hsa:4735; Q14132; Q15019; Q53QU3; Q8IUK9; Q96CB0"	"2q37 copy number variation syndrome"	"Anchoring of the basal body to the plasma membrane"	"2"	"0"	"109.4"	"59.8"	"90.4"	"103.5"	"92.5"	"121.3"	"440.4"	"433.9"	"317.1"	"524.3"	"814.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BU76"	"Multiple myeloma tumor-associated protein 2 OS=Homo sapiens OX=9606 GN=MMTAG2 PE=1 SV=1"	"5"	"1"	"2"	"1"	"263"	"29.4"	"10.02"	"546.85"	"4.94"	"1"	"1"	""	"non-structural extracellular;other cell component"	""	"Pf10159"	"79169"	"ENSG00000143793"	"MMTAG2"	"hsa:79169; Q6P5Y0; Q6ZTZ6; Q6ZWA6; Q8IZH3; Q9BU76"	""	"Neutrophil degranulation"	"1"	"0"	"24.0"	"20.6"	"25.5"	"28.2"	"24.8"	"33.6"	"72.6"	"62.3"	"49.5"	"79.8"	"88.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TEA8"	"D-aminoacyl-tRNA deacylase 1 OS=Homo sapiens OX=9606 GN=DTD1 PE=1 SV=2"	"8"	"1"	"2"	"1"	"209"	"23.4"	"8.24"	"449.16"	"4.92"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02580"	"92675"	"ENSG00000125821"	"DTD1"	"A8K5X5; D3DW37; hsa:92675; Q496D1; Q5W184; Q8TEA8; Q8WXU8; Q9BW67; Q9H464; Q9H474"	""	""	"0"	"0"	"5.2"	"6.3"	"4.7"	"5.3"	"3.7"	"6.2"	"16.6"	"17.6"	"20.1"	"30.8"	"58.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14562"	"ATP-dependent RNA helicase DHX8 OS=Homo sapiens OX=9606 GN=DHX8 PE=1 SV=1"	"3"	"3"	"4"	"3"	"1220"	"139.2"	"8.32"	"478.66"	"4.92"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00271, Pf00575, Pf04408, Pf07717"	"1659"	"ENSG00000067596"	"DHX8"	"hsa:1659; Q14562"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"13.6"	"8.1"	"15.1"	"16.6"	"16.3"	"16.5"	"35.2"	"34.2"	"30.6"	"44.3"	"48.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2S7"	"Polymerase delta-interacting protein 2 OS=Homo sapiens OX=9606 GN=POLDIP2 PE=1 SV=1"	"6"	"2"	"4"	"2"	"368"	"42.0"	"8.63"	"661.83"	"4.90"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytoskeleton;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity"	"Pf04379, Pf08755"	"26073"	"ENSG00000004142"	"POLDIP2"	"B2R846; hsa:26073; Q96JE4; Q9Y2S7"	""	""	"0"	"0"	"72.0"	"40.0"	"48.4"	"57.8"	"55.3"	"68.9"	"86.7"	"84.5"	"73.0"	"96.7"	"142.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H814"	"Phosphorylated adapter RNA export protein OS=Homo sapiens OX=9606 GN=PHAX PE=1 SV=1"	"5"	"2"	"4"	"2"	"394"	"44.4"	"5.40"	"575.48"	"4.90"	"2"	"2"	"transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf10258"	"51808"	"ENSG00000164902"	"PHAX"	"hsa:51808; Q9H814; Q9H8W1"	""	"RNA polymerase II transcribes snRNA genes; snRNP Assembly"	"2"	"0"	"13.7"	"8.5"	"14.8"	"10.5"	"12.4"	"13.7"	"27.1"	"29.5"	"18.0"	"19.6"	"27.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25208"	"Nuclear transcription factor Y subunit beta OS=Homo sapiens OX=9606 GN=NFYB PE=1 SV=2"	"8"	"1"	"2"	"1"	"207"	"22.8"	"4.59"	"481.25"	"4.88"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00808"	"4801"	"ENSG00000120837"	"NFYB"	"A8K7B9; hsa:4801; P25208; Q96IY8"	""	"PPARA activates gene expression; Activation of gene expression by SREBF (SREBP); FOXO-mediated transcription of cell death genes; ATF4 activates genes in response to endoplasmic reticulum  stress; ATF6 (ATF6-alpha) activates chaperone genes"	"5"	"0"	"30.3"	"23.6"	"25.6"	"35.8"	"24.6"	"40.7"	"70.4"	"69.8"	"54.4"	"79.1"	"83.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75694"	"Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1"	"2"	"3"	"5"	"3"	"1391"	"155.1"	"6.16"	"785.30"	"4.87"	"3"	"2"	"cell-cell signaling;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;nucleus"	"other molecular function"	"Pf03177, Pf08801"	"9631"	"ENSG00000113569"	"NUP155"	"hsa:9631; O75694; Q9UBE9; Q9UFL5"	""	"HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Postmitotic nuclear pore complex (NPC) reformation"	"29"	"0"	"303.6"	"177.3"	"264.4"	"246.2"	"245.4"	"299.9"	"368.6"	"334.9"	"265.0"	"371.6"	"500.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5SRE5"	"Nucleoporin NUP188 homolog OS=Homo sapiens OX=9606 GN=NUP188 PE=1 SV=1"	"2"	"2"	"4"	"2"	"1749"	"195.9"	"6.73"	"530.38"	"4.86"	"2"	"2"	"transport"	"cytosol;nucleus"	"other molecular function"	"Pf10487"	"23511"	"ENSG00000095319"	"NUP188"	"hsa:23511; Q14675; Q2TA87; Q5SRE5; Q7Z3K8; Q8IWF1"	""	"Vpr-mediated nuclear import of PICs; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Regulation of HSF1-mediated heat shock response; HCMV Late Events; HCMV Early Events; Transcriptional regulation by small RNAs; SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Transport of Mature mRNA Derived from an Intronless Transcript; tRNA processing in the nucleus; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; snRNP Assembly; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); Postmitotic nuclear pore complex (NPC) reformation"	"29"	"0"	"19.8"	"13.2"	"17.2"	"17.9"	"13.8"	"18.8"	"30.0"	"29.2"	"29.1"	"35.0"	"48.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NZZ3"	"Charged multivesicular body protein 5 OS=Homo sapiens OX=9606 GN=CHMP5 PE=1 SV=1"	"6"	"2"	"4"	"2"	"219"	"24.6"	"4.83"	"575.43"	"4.86"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	""	"Pf03357"	"51510"	"ENSG00000086065"	"CHMP5"	"B2RD95; B4DIR6; hsa:51510; Q5VXW2; Q96AV2; Q9HB68; Q9NYS4; Q9NZZ3; Q9Y323"	"Ferroptosis"	"Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT)"	"3"	"0"	"406.3"	"191.9"	"311.0"	"332.3"	"238.8"	"366.8"	"522.4"	"442.2"	"319.4"	"503.4"	"859.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P56192"	"Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2"	"4"	"2"	"3"	"2"	"900"	"101.1"	"6.16"	"276.71"	"4.86"	"1"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00043, Pf00458, Pf09334, Pf18485, Pf19303"	"4141"	"ENSG00000166986"	"MARS1"	"B3KVK7; hsa:4141; P56192; Q14895; Q53H14; Q96A15; Q96BZ0; Q9NSE0"	""	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P43246"	"DNA mismatch repair protein Msh2 OS=Homo sapiens OX=9606 GN=MSH2 PE=1 SV=1"	"3"	"1"	"1"	"1"	"934"	"104.7"	"5.77"	""	"4.85"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00488, Pf01624, Pf05188, Pf05190, Pf05192"	"4436"	"ENSG00000095002"	"MSH2"	"B4E2Z2; hsa:4436; O75488; P43246"	"RAC1/PAK1/p38/MMP2 pathway; Chromosomal and microsatellite instability in colorectal cancer ; Ciliary landscape; DNA repair pathways, full network; p53 transcriptional gene network; DNA mismatch repair"	"TP53 Regulates Transcription of DNA Repair Genes; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta); Defective Mismatch Repair Associated With MSH3; Defective Mismatch Repair Associated With MSH2; Defective Mismatch Repair Associated With MSH6"	"12"	"0"	"16.4"	"12.8"	"19.8"	"20.9"	"31.2"	"26.8"	"35.6"	"37.4"	"23.4"	"40.6"	"59.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBB9"	"Tuftelin-interacting protein 11 OS=Homo sapiens OX=9606 GN=TFIP11 PE=1 SV=1"	"3"	"2"	"4"	"2"	"837"	"96.8"	"5.67"	"578.26"	"4.83"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"extracellular matrix;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01585, Pf07842, Pf12457"	"24144"	"ENSG00000100109"	"TFIP11"	"hsa:24144; O95908; Q20WL0; Q5H8V8; Q9UBB9; Q9UGV7; Q9Y2Q8"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"13.9"	"14.1"	"19.1"	"17.6"	"19.3"	"15.4"	"34.5"	"32.6"	"19.1"	"45.6"	"52.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P02768"	"Serum albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2"	"7"	"3"	"4"	"3"	"609"	"69.3"	"6.28"	"1500.13"	"4.83"	"3"	"1"	"stress response;other biological processes"	"non-structural extracellular;ER/Golgi;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00273"	"213"	"ENSG00000163631"	"ALB"	"E7ESS9; hsa:213; O95574; P02768; P04277; Q13140; Q645G4; Q68DN5; Q6UXK4; Q86YG0; Q8IUK7; Q9P157; Q9P1I7; Q9UHS3; Q9UJZ0"	"Selenium micronutrient network; Vitamin B12 metabolism; Folate metabolism; Complement system; VEGFA-VEGFR2 signaling"	"Scavenging of heme from plasma; Platelet degranulation ; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Cytoprotection by HMOX1; Aspirin ADME; Ciprofloxacin ADME; Recycling of bile acids and salts; Prednisone ADME; Heme degradation; HDL remodeling; Heme biosynthesis"	"17"	"0"	"19.0"	"14.9"	"29.9"	"15.7"	"21.3"	"17.9"	"146.7"	"141.7"	"132.7"	"191.7"	"175.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16537"	"Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform OS=Homo sapiens OX=9606 GN=PPP2R5E PE=1 SV=1"	"3"	"1"	"2"	"1"	"467"	"54.7"	"6.95"	"539.41"	"4.82"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction"	"cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf01603"	"5529"	"ENSG00000154001"	"PPP2R5E"	"A4FU37; B7ZAW5; B7ZKK8; B7ZKK9; hsa:5529; J3KQN6; Q16537; Q52LW4"	"Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Wnt signaling pathway and pluripotency; PI3K-Akt signaling pathway; Glycogen synthesis and degradation; Cohesin complex - Cornelia de Lange syndrome; DNA damage response (only ATM dependent)"	"Resolution of Sister Chromatid Cohesion; CTLA4 inhibitory signaling; Separation of Sister Chromatids; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Negative regulation of MAPK pathway; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Disassembly of the destruction complex and recruitment of AXIN to the membrane; RAF activation; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; APC truncation mutants have impaired AXIN binding; AXIN missense mutants destabilize the destruction complex; Truncations of AMER1 destabilize the destruction complex; Platelet sensitization by LDL"	"28"	"0"	"26.9"	"13.8"	"22.7"	"23.7"	"17.9"	"23.7"	"51.7"	"35.3"	"18.9"	"54.2"	"68.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75306"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2"	"4"	"1"	"2"	"1"	"463"	"52.5"	"7.55"	"388.42"	"4.80"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;mitochondrion;nucleus"	"transporter activity;other molecular function"	"Pf00346"	"4720"	"ENSG00000158864"	"NDUFS2"	"D3DVG7; hsa:4720; J3KPM7; O75306; Q5VTW0; Q969P3; Q9UEV3"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"14.1"	"15.3"	"20.0"	"21.3"	"22.0"	"23.7"	"39.3"	"30.7"	"24.1"	"33.7"	"48.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WW12"	"PEST proteolytic signal-containing nuclear protein OS=Homo sapiens OX=9606 GN=PCNP PE=1 SV=2"	"10"	"2"	"4"	"2"	"178"	"18.9"	"7.49"	"574.39"	"4.80"	"2"	"2"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes"	"nucleus"	""	"Pf15473"	"57092"	"ENSG00000081154"	"PCNP"	"B2RBE7; D3DN52; hsa:57092; Q53GF3; Q6AI44; Q8WW12; Q96CU3; Q9NS81"	""	""	"0"	"0"	"51.9"	"24.3"	"36.1"	"26.8"	"35.6"	"38.6"	"71.2"	"68.7"	"56.6"	"71.7"	"110.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75940"	"Survival of motor neuron-related-splicing factor 30 OS=Homo sapiens OX=9606 GN=SMNDC1 PE=1 SV=1"	"13"	"3"	"5"	"3"	"238"	"26.7"	"7.24"	"897.74"	"4.80"	"3"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf06003"	"10285"	"ENSG00000119953"	"SMNDC1"	"B2RA27; D3DRB1; hsa:10285; O75940; Q5T3K6"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"244.9"	"123.7"	"208.1"	"220.6"	"230.1"	"243.2"	"849.4"	"780.0"	"515.1"	"815.0"	"1431.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52701"	"DNA mismatch repair protein Msh6 OS=Homo sapiens OX=9606 GN=MSH6 PE=1 SV=2"	"2"	"3"	"5"	"3"	"1360"	"152.7"	"6.90"	"764.91"	"4.79"	"3"	"2"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00488, Pf00855, Pf01624, Pf05188, Pf05190, Pf05192"	"2956"	"ENSG00000116062"	"MSH6"	"B4DF41; B4E3I4; F5H2F9; hsa:2956; O43706; O43917; P52701; Q8TCX4; Q9BTB5"	"Glioblastoma signaling pathways; Retinoblastoma gene in cancer; Chromosomal and microsatellite instability in colorectal cancer ; DNA repair pathways, full network; DNA mismatch repair"	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Defective Mismatch Repair Associated With MSH2; Defective Mismatch Repair Associated With MSH6"	"8"	"0"	"206.1"	"129.1"	"154.1"	"155.8"	"190.8"	"202.2"	"431.4"	"385.2"	"294.9"	"446.2"	"597.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z7K0"	"COX assembly mitochondrial protein homolog OS=Homo sapiens OX=9606 GN=CMC1 PE=1 SV=1"	"16"	"1"	"1"	"1"	"106"	"12.5"	"8.63"	""	"4.79"	""	"1"	""	"mitochondrion"	"other molecular function"	"Pf08583"	"152100"	"ENSG00000187118"	"CMC1"	"hsa:152100; Q68DJ7; Q7Z7K0"	"Mitochondrial complex IV assembly"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9ULR0"	"Pre-mRNA-splicing factor ISY1 homolog OS=Homo sapiens OX=9606 GN=ISY1 PE=1 SV=3"	"7"	"1"	"2"	"1"	"285"	"33.0"	"5.17"	"500.92"	"4.76"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf06246"	"100534599; 57461"	"ENSG00000240682"	"ISY1"	"hsa:100534599; hsa:57461; Q96IL2; Q9BT05; Q9ULR0"	""	"mRNA Splicing - Major Pathway; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NPF8"	"Arf-GAP with dual PH domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ADAP2 PE=1 SV=1"	"4"	"2"	"4"	"1"	"381"	"44.3"	"9.36"	"576.11"	"4.74"	"2"	"2"	"developmental processes;other biological processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf01412"	"55803"	"ENSG00000184060"	"ADAP2"	"hsa:55803; Q8N4Q6; Q96SD5; Q9NPF8"	"TYROBP causal network in microglia"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2Q9"	"28S ribosomal protein S28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS28 PE=1 SV=1"	"10"	"2"	"4"	"2"	"187"	"20.8"	"9.10"	"633.74"	"4.74"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	""	"Pf10246"	"28957"	"ENSG00000147586"	"MRPS28"	"B2RDZ7; hsa:28957; Q96Q21; Q9Y2Q9"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"65.5"	"43.6"	"62.6"	"61.0"	"49.0"	"58.6"	"113.4"	"102.0"	"73.7"	"94.8"	"129.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26640"	"Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS1 PE=1 SV=4"	"2"	"3"	"5"	"3"	"1264"	"140.4"	"7.59"	"1206.26"	"4.74"	"3"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol"	"other molecular function"	"Pf00043, Pf00133, Pf08264"	"7407"	"ENSG00000096171; ENSG00000204394; ENSG00000224264; ENSG00000226589; ENSG00000231116"	"VARS1"	"B0V1N1; B4DZ61; hsa:7407; P26640; Q5JQ90; Q96E77; Q9UQM2"	"Amino acid metabolism"	"Cytosolic tRNA aminoacylation"	"2"	"0"	"63.7"	"38.3"	"45.9"	"64.2"	"55.3"	"72.6"	"86.1"	"76.0"	"59.8"	"79.4"	"135.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07339"	"Cathepsin D OS=Homo sapiens OX=9606 GN=CTSD PE=1 SV=1"	"2"	"1"	"4"	"1"	"412"	"44.5"	"6.54"	"759.68"	"4.73"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"other membranes;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00026, Pf07966"	"1509"	"ENSG00000117984"	"CTSD"	"hsa:1509; P07339; Q6IB57"	"Prolactin signaling pathway; 8p23.1 copy number variation syndrome"	"MHC class II antigen presentation; Collagen degradation; Neutrophil degranulation; Estrogen-dependent gene expression; Insulin receptor recycling; Metabolism of Angiotensinogen to Angiotensins"	"8"	"0"	"32.6"	"16.6"	"47.0"	"30.3"	"30.2"	"35.1"	"48.0"	"37.2"	"36.7"	"58.2"	"69.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96MU7"	"YTH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=YTHDC1 PE=1 SV=3"	"2"	"2"	"3"	"2"	"727"	"84.6"	"6.23"	"334.43"	"4.72"	"1"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;nucleus"	"nucleic acid binding activity"	"Pf04146"	"91746"	"ENSG00000083896; ENSG00000275272"	"YTHDC1"	"hsa:91746; Q4W5Q3; Q7Z622; Q8TF35; Q96MU7"	""	""	"0"	"0"	"352.6"	"215.6"	"302.3"	"278.9"	"315.9"	"306.1"	"701.3"	"579.0"	"423.7"	"686.7"	"960.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6W5"	"Wiskott-Aldrich syndrome protein family member 2 OS=Homo sapiens OX=9606 GN=WASF2 PE=1 SV=3"	"3"	"1"	"4"	"1"	"498"	"54.3"	"5.53"	"528.49"	"4.72"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02205"	"10163"	"ENSG00000158195"	"WASF2"	"B4DZN0; hsa:10163; O60794; Q9UDY7; Q9Y6W5"	"Regulation of actin cytoskeleton"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RAC1 GTPase cycle; RHO GTPases Activate WASPs and WAVEs; VEGFA-VEGFR2 Pathway; RAC2 GTPase cycle; RAC3 GTPase cycle"	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HCC0"	"Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC2 PE=1 SV=1"	"8"	"5"	"6"	"5"	"563"	"61.3"	"7.68"	"1528.86"	"4.71"	"4"	"2"	"other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf01039"	"64087"	"ENSG00000131844"	"MCCC2"	"A6NIY9; hsa:64087; Q96C27; Q9HCC0; Q9Y4L7"	""	"Biotin transport and metabolism; Branched-chain amino acid catabolism; Defective HLCS causes multiple carboxylase deficiency"	"3"	"0"	"160.2"	"172.5"	"222.1"	"167.6"	"194.3"	"176.3"	"304.4"	"304.8"	"253.1"	"421.2"	"649.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NUQ3"	"Gamma-taxilin OS=Homo sapiens OX=9606 GN=TXLNG PE=1 SV=2"	"5"	"3"	"5"	"2"	"528"	"60.5"	"7.52"	"861.07"	"4.71"	"3"	"2"	"cell cycle OR cell proliferation;other biological processes"	"other membranes;cytosol;nucleus"	"other molecular function"	"Pf09728"	"55787"	"ENSG00000086712"	"TXLNG"	"hsa:55787; Q2KQ75; Q5JNZ7; Q9NUQ3; Q9P0X1"	""	""	"0"	"0"	"25.1"	"18.8"	"25.1"	"27.4"	"30.4"	"31.8"	"157.3"	"162.6"	"140.6"	"220.8"	"372.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60783"	"28S ribosomal protein S14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS14 PE=1 SV=1"	"12"	"1"	"2"	"1"	"128"	"15.1"	"11.41"	"425.31"	"4.70"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf00253"	"63931"	"ENSG00000120333"	"MRPS14"	"hsa:63931; O60783; Q5R358"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"22.5"	"14.8"	"26.2"	"24.3"	"19.6"	"26.2"	"43.0"	"40.1"	"34.7"	"52.1"	"62.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H977"	"WD repeat-containing protein 54 OS=Homo sapiens OX=9606 GN=WDR54 PE=1 SV=1"	"4"	"1"	"2"	"1"	"334"	"35.9"	"6.20"	""	"4.67"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"other molecular function"	""	"84058"	"ENSG00000005448"	"WDR54"	"B9A049; D6W5I3; hsa:84058; Q53H85; Q86V45; Q9H977"	""	""	"0"	"0"	"154.5"	"39.1"	"139.5"	"98.3"	"103.7"	"88.8"	"291.0"	"171.1"	"55.8"	"199.1"	"666.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14573"	"Inositol 1,4,5-trisphosphate receptor type 3 OS=Homo sapiens OX=9606 GN=ITPR3 PE=1 SV=2"	"1"	"3"	"5"	"1"	"2671"	"303.9"	"6.48"	"818.98"	"4.66"	"3"	"2"	"transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00520, Pf01365, Pf02815, Pf08454, Pf08709"	"3710"	"ENSG00000096433"	"ITPR3"	"hsa:3710; Q14573; Q14649; Q5TAQ2"	"Alzheimer's disease and miRNA effects; Myometrial relaxation and contraction pathways; MFAP5-mediated ovarian cancer cell motility and invasiveness; GPR40 pathway; Vitamin D-sensitive calcium signaling in depression; Airway smooth muscle cell contraction; Pleural mesothelioma; Alzheimer's disease; GDNF signaling; Calcium regulation in cardiac cells"	"Ion homeostasis; Role of phospholipids in phagocytosis; FCERI mediated Ca+2 mobilization; FCGR3A-mediated IL10 synthesis; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Sensory perception of sweet, bitter, and umami (glutamate) taste; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Ca2+ pathway; VEGFR2 mediated cell proliferation; Elevation of cytosolic Ca2+ levels; PLC beta mediated events; DAG and IP3 signaling; CLEC7A (Dectin-1) induces NFAT activation; Effects of PIP2 hydrolysis"	"25"	"0"	"7.3"	"7.4"	"9.9"	"8.4"	"11.2"	"8.7"	"16.0"	"13.8"	"10.1"	"15.4"	"16.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EY5"	"Multivesicular body subunit 12A OS=Homo sapiens OX=9606 GN=MVB12A PE=1 SV=1"	"7"	"1"	"2"	"1"	"273"	"28.8"	"8.91"	"494.98"	"4.65"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf10240"	"93343"	"ENSG00000141971"	"MVB12A"	"hsa:93343; Q96EY5; Q96I18"	"7q11.23 copy number variation syndrome"	"Budding and maturation of HIV virion; Membrane binding and targetting of GAG proteins; Endosomal Sorting Complex Required For Transport (ESCRT); Late endosomal microautophagy; HCMV Late Events"	"6"	"0"	"20.7"	"15.9"	"19.6"	"19.4"	"21.9"	"23.8"	"42.8"	"52.7"	"48.5"	"96.6"	"120.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96FF9"	"Sororin OS=Homo sapiens OX=9606 GN=CDCA5 PE=1 SV=1"	"3"	"1"	"4"	"1"	"252"	"27.6"	"9.61"	"575.90"	"4.65"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf09666"	"113130"	"ENSG00000146670"	"CDCA5"	"A8K625; hsa:113130; Q96FF9"	""	"Resolution of Sister Chromatid Cohesion; Separation of Sister Chromatids; Establishment of Sister Chromatid Cohesion"	"3"	"0"	"159.3"	"82.3"	"101.8"	"138.8"	"115.0"	"145.2"	"495.3"	"507.5"	"340.4"	"466.5"	"622.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5EBL8"	"PDZ domain-containing protein 11 OS=Homo sapiens OX=9606 GN=PDZD11 PE=1 SV=2"	"11"	"2"	"4"	"1"	"140"	"16.1"	"7.21"	"495.81"	"4.64"	"2"	"2"	"cell-cell signaling;cell organization and biogenesis;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;other cell component"	""	"Pf00595"	"51248"	"ENSG00000120509"	"PDZD11"	"D3DVU3; hsa:51248; Q5EBL8; Q6UWE1; Q9P0Q1"	""	"Ion transport by P-type ATPases; Ion influx/efflux at host-pathogen interface; Transport of vitamins, nucleosides, and related molecules; Biotin transport and metabolism; Vitamin B5 (pantothenate) metabolism"	"5"	"0"	"6.6"	"6.2"	"5.0"	"4.9"	"9.0"	"5.6"	"11.6"	"15.4"	"10.9"	"13.1"	"23.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UL18"	"Protein argonaute-1 OS=Homo sapiens OX=9606 GN=AGO1 PE=1 SV=3"	"3"	"2"	"3"	"2"	"857"	"97.2"	"9.16"	"250.38"	"4.62"	"1"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02170, Pf02171, Pf08699, Pf16486, Pf16487, Pf16488"	"26523"	"ENSG00000092847"	"AGO1"	"hsa:26523; Q5TA57; Q6P4S0; Q9UL18"	"Modulators of TCR signaling and T cell activation"	"Transcriptional regulation by small RNAs; NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux; Oxidative Stress Induced Senescence; MAPK6/MAPK4 signaling; Estrogen-dependent gene expression; Pre-NOTCH Transcription and Translation; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; TP53 Regulates Metabolic Genes; Oncogene Induced Senescence; Transcriptional Regulation by VENTX; Ca2+ pathway; Regulation of MECP2 expression and activity; MicroRNA (miRNA) biogenesis; Small interfering RNA (siRNA) biogenesis; Regulation of RUNX1 Expression and Activity; Regulation of CDH11 mRNA translation by microRNAs; Regulation of NPAS4 mRNA translation; Post-transcriptional silencing by small RNAs; Competing endogenous RNAs (ceRNAs) regulate PTEN translation"	"22"	"0"	"28.0"	"17.2"	"26.3"	"24.7"	"30.4"	"29.6"	"80.4"	"74.8"	"69.8"	"91.3"	"101.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35222"	"Catenin beta-1 OS=Homo sapiens OX=9606 GN=CTNNB1 PE=1 SV=1"	"3"	"3"	"5"	"2"	"781"	"85.4"	"5.86"	"810.80"	"4.59"	"3"	"2"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00514"	"1499"	"ENSG00000168036"	"CTNNB1"	"A8K1L7; hsa:1499; P35222; Q8NEW9; Q8NI94; Q9H391"	"Androgen receptor signaling pathway; MicroRNAs in cardiomyocyte hypertrophy; Heart development; TNF-related weak inducer of apoptosis (TWEAK) signaling pathway; Alzheimer's disease and miRNA effects; Neural crest differentiation; Arrhythmogenic right ventricular cardiomyopathy; Pathogenic Escherichia coli infection; Corticotropin-releasing hormone signaling pathway; Adipogenesis; Gastric cancer network 2; Brain-derived neurotrophic factor (BDNF) signaling pathway; Primary focal segmental glomerulosclerosis (FSGS); Endoderm differentiation; Ectoderm differentiation; Extracellular vesicle-mediated signaling in recipient cells; Focal adhesion; Ectoderm differentiation; RAC1/PAK1/p38/MMP2 pathway; Wnt signaling pathway; Regulation of Wnt / B-catenin signaling by small molecule compounds; Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Embryonic stem cell pluripotency pathways; H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity; OSX and miRNAs in tooth development; Wnt signaling pathway and pluripotency; PTF1A related regulatory pathway; Wnt signaling in kidney disease; Endometrial cancer; Chromosomal and microsatellite instability in colorectal cancer ; Epithelial to mesenchymal transition in colorectal cancer; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Ciliary landscape; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; Gastrin signaling pathway; Head and neck squamous cell carcinoma; Thyroid hormones production and peripheral downstream signaling effects; IL-18 signaling pathway; Osteoblast differentiation and related diseases; TGF-beta receptor signaling in skeletal dysplasias; Genes controlling nephrogenesis; GDNF/RET signaling axis; Mammalian disorder of sexual development; Influence of laminopathies on Wnt signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies; 1q21.1 copy number variation syndrome; 7q11.23 copy number variation syndrome; Development of ureteric collection system; Pleural mesothelioma; Alzheimer's disease; Urotensin-II-mediated signaling pathway; Markers of kidney cell lineage; TROP2 regulatory signaling; 8p23.1 copy number variation syndrome; A network map of Macrophage-stimulating protein (MSP) signaling; TGF-beta receptor signaling; Sudden infant death syndrome (SIDS) susceptibility pathways; DNA damage response (only ATM dependent)"	"Somitogenesis; Deactivation of the beta-catenin transactivating complex; InlA-mediated entry of Listeria monocytogenes into host cells; RHO GTPases activate IQGAPs; Formation of paraxial mesoderm; Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1); Formation of axial mesoderm; Myogenesis; Transcriptional Regulation by VENTX; Ca2+ pathway; Disassembly of the destruction complex and recruitment of AXIN to the membrane; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; Cardiogenesis; Germ layer formation at gastrulation; Formation of definitive endoderm; VEGFR2 mediated vascular permeability; Adherens junctions interactions; Regulation of CDH11 function; Regulation of CDH19 Expression and Function; CDH11 homotypic and heterotypic interactions; Binding of TCF/LEF:CTNNB1 to target gene promoters; RUNX3 regulates WNT signaling; Apoptotic cleavage of cell adhesion  proteins; LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production"	"96"	"0"	"55.7"	"32.0"	"51.8"	"36.0"	"47.7"	"49.0"	"59.9"	"66.6"	"35.9"	"78.7"	"92.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94905"	"Erlin-2 OS=Homo sapiens OX=9606 GN=ERLIN2 PE=1 SV=1"	"5"	"2"	"3"	"2"	"339"	"37.8"	"5.62"	"315.17"	"4.59"	"1"	"2"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf01145"	"11160"	"ENSG00000147475"	"ERLIN2"	"A0JLQ1; A8K5S9; B4DM38; D3DSW0; hsa:11160; O94905; Q6NW21; Q86VS6; Q86W49"	""	"ABC-family proteins mediated transport; Defective CFTR causes cystic fibrosis; Signaling by FGFR1 in disease; Signaling by plasma membrane FGFR1 fusions"	"4"	"0"	"171.2"	"105.0"	"139.6"	"116.7"	"159.4"	"154.6"	"195.7"	"174.5"	"124.9"	"242.1"	"325.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62312"	"U6 snRNA-associated Sm-like protein LSm6 OS=Homo sapiens OX=9606 GN=LSM6 PE=1 SV=1"	"29"	"3"	"5"	"3"	"80"	"9.1"	"9.58"	"816.50"	"4.59"	"3"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01423"	"11157"	"ENSG00000164167"	"LSM6"	"hsa:11157; P62312; Q4W5J5; Q9Y4Y8"	""	"mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease"	"2"	"0"	"437.1"	"292.5"	"395.5"	"250.2"	"328.9"	"344.7"	"674.2"	"637.0"	"530.6"	"830.5"	"974.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNP9"	"Peptidyl-prolyl cis-trans isomerase E OS=Homo sapiens OX=9606 GN=PPIE PE=1 SV=1"	"8"	"3"	"4"	"2"	"301"	"33.4"	"5.60"	"766.32"	"4.59"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00160"	"10450"	"ENSG00000084072"	"PPIE"	"B2R971; hsa:10450; O43634; O43635; Q32Q72; Q3S611; Q5TGA0; Q5TGA2; Q5TGA3; Q9UIZ5; Q9UNP9"	""	"mRNA Splicing - Major Pathway; Neutrophil degranulation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	"6"	"0"	"93.3"	"56.0"	"89.1"	"79.7"	"94.1"	"99.5"	"189.9"	"165.8"	"123.0"	"204.6"	"237.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22033"	"Methylmalonyl-CoA mutase, mitochondrial OS=Homo sapiens OX=9606 GN=MMUT PE=1 SV=4"	"3"	"2"	"3"	"2"	"750"	"83.1"	"6.93"	"236.28"	"4.57"	"1"	"2"	"other metabolic processes;developmental processes;other biological processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf01642, Pf02310"	"4594"	"ENSG00000146085"	"MMUT"	"A8K953; hsa:4594; P22033; Q5SYZ3; Q96B11; Q9UD64"	"Vitamin B12 metabolism; Amino acid metabolism"	"Propionyl-CoA catabolism; Defective MMAA causes MMA, cblA type; Defective MUT causes MMAM; Cobalamin (Cbl) metabolism"	"6"	"0"	"12.5"	"3.4"	"13.2"	"15.3"	"14.2"	"17.6"	"27.9"	"27.4"	"24.4"	"44.0"	"75.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WUA2"	"Peptidyl-prolyl cis-trans isomerase-like 4 OS=Homo sapiens OX=9606 GN=PPIL4 PE=1 SV=1"	"4"	"1"	"1"	"1"	"492"	"57.2"	"5.92"	""	"4.55"	""	"1"	"protein metabolism;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00076, Pf00160"	"85313"	"ENSG00000131013"	"PPIL4"	"B2RD34; hsa:85313; Q7Z3Q5; Q8WUA2"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"24.4"	"17.3"	"26.0"	"24.2"	"18.3"	"23.4"	"64.6"	"57.3"	"45.1"	"70.1"	"94.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HCG8"	"Pre-mRNA-splicing factor CWC22 homolog OS=Homo sapiens OX=9606 GN=CWC22 PE=1 SV=3"	"2"	"1"	"3"	"1"	"908"	"105.4"	"7.03"	"288.79"	"4.55"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity"	"Pf02847"	"57703"	"ENSG00000163510"	"CWC22"	"hsa:57703; Q05DC2; Q4G135; Q52LF0; Q6PEX2; Q7Z6I0; Q9H5L3; Q9H6Q6; Q9HCG8"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P17812"	"CTP synthase 1 OS=Homo sapiens OX=9606 GN=CTPS1 PE=1 SV=2"	"3"	"2"	"3"	"2"	"591"	"66.6"	"6.46"	"375.62"	"4.54"	"1"	"2"	"cell cycle OR cell proliferation;other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00117, Pf06418"	"1503"	"ENSG00000171793"	"CTPS1"	"B4DR64; D3DPW1; hsa:1503; P17812; Q5VW67; Q96GK6"	"Pyrimidine metabolism"	"Interconversion of nucleotide di- and triphosphates"	"2"	"0"	"49.9"	"31.5"	"50.0"	"51.5"	"49.1"	"54.1"	"99.9"	"72.5"	"59.8"	"124.2"	"123.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WWK9"	"Cytoskeleton-associated protein 2 OS=Homo sapiens OX=9606 GN=CKAP2 PE=1 SV=1"	"4"	"4"	"6"	"4"	"683"	"76.9"	"9.41"	"1145.70"	"4.53"	"4"	"2"	"cell cycle OR cell proliferation;other biological processes"	"cytoskeleton;other cell component"	""	"Pf15297"	"26586"	"ENSG00000136108"	"CKAP2"	"A2BDE0; A5YM58; B4DR35; E9PD90; hsa:26586; Q3KRA5; Q5VXB4; Q8IWV5; Q8IWV6; Q8WWK9; Q96FH9; Q9H012; Q9H0D0; Q9H988; Q9HC49; Q9NVG4"	""	""	"0"	"0"	"163.5"	"85.7"	"112.7"	"114.2"	"125.6"	"124.1"	"725.2"	"638.3"	"500.6"	"747.6"	"971.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14561"	"Acyl carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFAB1 PE=1 SV=3"	"9"	"1"	"2"	"1"	"156"	"17.4"	"4.93"	"463.43"	"4.53"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"other membranes;cytosol;mitochondrion;nucleus"	"translation activity;other molecular function"	"Pf00550"	"4706"	"ENSG00000004779"	"NDUFAB1"	"B2R4M1; hsa:4706; O14561; Q9UNV1"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Glyoxylate metabolism and glycine degradation; Mitochondrial Fatty Acid Beta-Oxidation; Complex I biogenesis"	"7"	"0"	"64.8"	"31.7"	"33.3"	"42.3"	"27.2"	"51.0"	"68.6"	"72.6"	"53.2"	"114.6"	"186.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62879"	"Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 OS=Homo sapiens OX=9606 GN=GNB2 PE=1 SV=3"	"5"	"1"	"2"	"1"	"340"	"37.3"	"6.00"	"402.42"	"4.52"	"1"	"1"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00400"	"2783"	"ENSG00000172354"	"GNB2"	"B3KPU1; hsa:2783; P11016; P54312; P62879"	"Corticotropin-releasing hormone signaling pathway; Myometrial relaxation and contraction pathways; G protein signaling pathways; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Ras signaling; Calcium regulation in cardiac cells"	"G alpha (12/13) signalling events; G alpha (q) signalling events; G alpha (i) signalling events; G alpha (z) signalling events; ADP signalling through P2Y purinoceptor 12; Extra-nuclear estrogen signaling; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; Thrombin signalling through proteinase activated receptors (PARs); Activation of G protein gated Potassium channels; G-protein activation; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; G beta:gamma signalling through PI3Kgamma; Prostacyclin signalling through prostacyclin receptor; Adrenaline,noradrenaline inhibits insulin secretion; Ca2+ pathway; G beta:gamma signalling through PLC beta; ADP signalling through P2Y purinoceptor 1; Glucagon-type ligand receptors; Thromboxane signalling through TP receptor; Vasopressin regulates renal water homeostasis via Aquaporins; Presynaptic function of Kainate receptors; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; G beta:gamma signalling through BTK; G beta:gamma signalling through CDC42; Inhibition  of voltage gated Ca2+ channels via Gbeta/gamma subunits; Glucagon signaling in metabolic regulation"	"36"	"0"	"36.8"	"25.1"	"36.6"	"23.8"	"30.5"	"28.4"	"40.4"	"36.4"	"38.4"	"69.3"	"70.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19404"	"NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV2 PE=1 SV=2"	"10"	"2"	"3"	"2"	"249"	"27.4"	"8.06"	"272.97"	"4.51"	"1"	"2"	"other metabolic processes;transport;developmental processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf01257"	"4729"	"ENSG00000178127"	"NDUFV2"	"hsa:4729; P19404; Q9BV41"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HB21"	"Pleckstrin homology domain-containing family A member 1 OS=Homo sapiens OX=9606 GN=PLEKHA1 PE=1 SV=2"	"5"	"2"	"4"	"2"	"404"	"45.5"	"8.56"	"540.09"	"4.50"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00169"	"59338"	"ENSG00000107679"	"PLEKHA1"	"B3KQ55; D3DRE2; hsa:59338; Q9BVK0; Q9HB21"	""	"Synthesis of PIPs at the plasma membrane"	"1"	"0"	"4.8"	"4.1"	"10.8"	"10.8"	"9.4"	"9.4"	"20.4"	"20.0"	"31.0"	"51.2"	"88.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6E0"	"Serine/threonine-protein kinase 24 OS=Homo sapiens OX=9606 GN=STK24 PE=1 SV=1"	"2"	"1"	"4"	"1"	"443"	"49.3"	"5.69"	"489.57"	"4.50"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"8428"	"ENSG00000102572"	"STK24"	"hsa:8428; O14840; Q5JV92; Q9Y6E0"	""	"Apoptotic cleavage of cellular proteins"	"2"	"0"	"98.0"	"58.3"	"105.4"	"96.3"	"89.4"	"102.2"	"409.3"	"409.4"	"275.4"	"398.0"	"501.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61927"	"60S ribosomal protein L37 OS=Homo sapiens OX=9606 GN=RPL37 PE=1 SV=2"	"20"	"3"	"5"	"3"	"97"	"11.1"	"11.74"	"768.31"	"4.50"	"3"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf01907"	"6167"	"ENSG00000145592"	"RPL37"	"B2R4H2; hsa:6167; P02403; P61927; Q6IBB4; Q99883"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"738.3"	"437.0"	"692.3"	"479.3"	"591.5"	"555.3"	"2550.4"	"2159.3"	"1477.3"	"2434.1"	"2809.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O76094"	"Signal recognition particle subunit SRP72 OS=Homo sapiens OX=9606 GN=SRP72 PE=1 SV=3"	"3"	"2"	"3"	"2"	"671"	"74.6"	"9.26"	"260.21"	"4.50"	"1"	"2"	"transport"	"cytosol;ER/Golgi;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf08492, Pf13181, Pf17004"	"6731"	"ENSG00000174780"	"SRP72"	"G5E9Z8; hsa:6731; O76094; Q7Z3C0"	""	"SRP-dependent cotranslational protein targeting to membrane"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q08378"	"Golgin subfamily A member 3 OS=Homo sapiens OX=9606 GN=GOLGA3 PE=1 SV=2"	"1"	"2"	"3"	"1"	"1498"	"167.3"	"5.44"	"250.34"	"4.49"	"1"	"2"	""	"other membranes;cytosol;ER/Golgi;nucleus"	""	""	"2802"	"ENSG00000090615"	"GOLGA3"	"A5PKX6; hsa:2802; O43241; Q08378; Q6P9C7; Q86XW3; Q8TDA9; Q8WZA3"	""	"RND2 GTPase cycle"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IWX8"	"Calcium homeostasis endoplasmic reticulum protein OS=Homo sapiens OX=9606 GN=CHERP PE=1 SV=3"	"2"	"3"	"5"	"3"	"916"	"103.6"	"9.04"	"791.16"	"4.47"	"3"	"2"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf01585, Pf01805, Pf04818"	"10523"	"ENSG00000085872"	"CHERP"	"hsa:10523; O00302; Q4G0Y5; Q8IWX8; Q8WU30; Q99492"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"481.3"	"335.4"	"408.3"	"417.2"	"463.1"	"476.5"	"717.3"	"658.2"	"465.5"	"777.1"	"930.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6B6"	"GTP-binding protein SAR1b OS=Homo sapiens OX=9606 GN=SAR1B PE=1 SV=1"	"9"	"2"	"3"	"1"	"198"	"22.4"	"6.11"	"233.33"	"4.46"	"1"	"2"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;ER/Golgi"	"other molecular function"	"Pf00025"	"51128"	"ENSG00000152700"	"SAR1B"	"D3DQA4; hsa:51128; Q567T4; Q9Y6B6"	"Sterol regulatory element-binding proteins (SREBP) signaling; Cholesterol metabolism; Enterocyte cholesterol metabolism"	"MHC class II antigen presentation; SARS-CoV-2 activates/modulates innate and adaptive immune responses; COPII-mediated vesicle transport; Cargo concentration in the ER; Regulation of cholesterol biosynthesis by SREBP (SREBF); Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Chylomicron assembly"	"10"	"0"	"73.7"	"39.8"	"64.6"	"52.7"	"63.7"	"70.0"	"87.2"	"100.3"	"89.0"	"130.1"	"218.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H3G5"	"Probable serine carboxypeptidase CPVL OS=Homo sapiens OX=9606 GN=CPVL PE=1 SV=2"	"4"	"2"	"3"	"2"	"476"	"54.1"	"5.62"	"263.07"	"4.46"	"1"	"2"	"protein metabolism"	""	"other molecular function"	"Pf00450"	"54504"	"ENSG00000106066"	"CPVL"	"A4D1A4; hsa:54504; Q6UX20; Q8NBL7; Q96AR7; Q9H3G5; Q9HB41"	""	""	"0"	"0"	"32.3"	"24.8"	"31.5"	"28.5"	"33.7"	"40.7"	"74.6"	"71.3"	"61.4"	"90.6"	"127.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96E11"	"Ribosome-recycling factor, mitochondrial OS=Homo sapiens OX=9606 GN=MRRF PE=1 SV=1"	"8"	"1"	"1"	"1"	"262"	"29.3"	"9.79"	""	"4.46"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"mitochondrion"	"translation activity"	"Pf01765"	"92399"	"ENSG00000148187"	"MRRF"	"A8K6D8; A8K6Z4; B7Z4X5; B7Z6P7; hsa:92399; Q5RKT1; Q5T7T0; Q5T7T1; Q5T7T2; Q5T7T3; Q5T7T4; Q5T7T5; Q96E11"	""	"Mitochondrial translation termination"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y333"	"U6 snRNA-associated Sm-like protein LSm2 OS=Homo sapiens OX=9606 GN=LSM2 PE=1 SV=1"	"22"	"3"	"5"	"3"	"95"	"10.8"	"6.52"	"901.00"	"4.45"	"3"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01423"	"57819"	"ENSG00000172850; ENSG00000204392; ENSG00000224979; ENSG00000225998; ENSG00000231502; ENSG00000236826"	"LSM2"	"hsa:57819; Q6FGG1; Q9Y333"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease"	"3"	"0"	"624.6"	"385.0"	"503.0"	"354.5"	"423.6"	"446.7"	"1010.4"	"882.5"	"682.7"	"1148.5"	"1686.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00918"	"Carbonic anhydrase 2 OS=Homo sapiens OX=9606 GN=CA2 PE=1 SV=2"	"6"	"1"	"2"	"1"	"260"	"29.2"	"7.40"	"507.26"	"4.45"	"1"	"1"	"transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00194"	"760"	"ENSG00000104267"	"CA2"	"B2R7G8; hsa:760; P00918; Q6FI12; Q96ET9"	"Proximal tubule transport"	"Reversible hydration of carbon dioxide; Erythrocytes take up carbon dioxide and release oxygen; Erythrocytes take up oxygen and release carbon dioxide"	"4"	"0"	"38.9"	"18.3"	"35.4"	"22.9"	"33.7"	"31.1"	"35.3"	"22.0"	"27.0"	"42.8"	"64.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UFG5"	"UPF0449 protein C19orf25 OS=Homo sapiens OX=9606 GN=C19orf25 PE=1 SV=2"	"25"	"2"	"3"	"2"	"118"	"12.9"	"5.07"	"897.30"	"4.45"	"2"	"1"	""	""	""	"Pf15136"	"148223"	"ENSG00000119559"	"C19orf25"	"B3KQN6; hsa:148223; Q8N9R7; Q8WV94; Q9UFG5"	""	""	"0"	"0"	"98.1"	"71.6"	"117.2"	"83.6"	"101.5"	"100.0"	"162.9"	"164.3"	"138.6"	"189.5"	"224.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62333"	"26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1"	"4"	"1"	"2"	"1"	"389"	"44.1"	"7.49"	"527.13"	"4.45"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf16450, Pf17862"	"5706"	"ENSG00000100519"	"PSMC6"	"B2R975; hsa:5706; P49719; P62333; Q6IBU3; Q92524"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"Regulation of expression of SLITs and ROBOs; The role of GTSE1 in G2/M progression after G2 checkpoint; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; SARS-CoV-1 targets host intracellular signalling and regulatory pathways"	"65"	"0"	"80.3"	"49.8"	"59.6"	"62.5"	"78.2"	"66.0"	"118.3"	"117.9"	"84.7"	"134.2"	"167.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NVM9"	"Integrator complex subunit 13 OS=Homo sapiens OX=9606 GN=INTS13 PE=1 SV=2"	"7"	"3"	"3"	"3"	"706"	"80.2"	"6.70"	"396.25"	"4.45"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf10221"	"55726"	"ENSG00000064102"	"INTS13"	"B4DNK1; hsa:55726; Q86WE2; Q96HM2; Q9BTX2; Q9NTB6; Q9NVM5; Q9NVM9"	"1p36 copy number variation syndrome"	"RNA polymerase II transcribes snRNA genes"	"2"	"0"	"30.8"	"16.2"	"19.5"	"28.3"	"30.5"	"35.2"	"56.2"	"58.6"	"44.0"	"49.3"	"58.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14156"	"Protein EFR3 homolog A OS=Homo sapiens OX=9606 GN=EFR3A PE=1 SV=2"	"3"	"2"	"2"	"2"	"821"	"92.9"	"6.70"	""	"4.45"	""	"2"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol"	""	""	"23167"	"ENSG00000132294"	"EFR3A"	"A7MD19; hsa:23167; Q14156; Q2VPK2; Q63HL7; Q68DX1; Q6IQ18"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62273"	"40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2"	"11"	"1"	"2"	"1"	"56"	"6.7"	"10.13"	""	"4.44"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00253"	"6235"	"ENSG00000213741"	"RPS29"	"A8MZ73; hsa:6235; P30054; P62273"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"683.1"	"297.3"	"299.0"	"222.1"	"285.6"	"327.1"	"1151.2"	"1039.2"	"726.1"	"1213.5"	"1946.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P10155"	"60 kDa SS-A/Ro ribonucleoprotein OS=Homo sapiens OX=9606 GN=RO60 PE=1 SV=2"	"3"	"1"	"2"	"1"	"538"	"60.6"	"8.03"	"573.42"	"4.42"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05731"	"6738"	"ENSG00000116747"	"RO60"	"B2RBB9; hsa:6738; P10155; Q5LJ98; Q5LJ99; Q5LJA0; Q86WL3; Q86WL4; Q92787; Q9H1W6"	""	""	"0"	"0"	"70.6"	"59.0"	"102.3"	"84.2"	"102.3"	"98.8"	"149.6"	"133.3"	"90.0"	"150.3"	"193.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UGN5"	"Poly [ADP-ribose] polymerase 2 OS=Homo sapiens OX=9606 GN=PARP2 PE=1 SV=2"	"4"	"1"	"1"	"1"	"583"	"66.2"	"8.88"	""	"4.42"	""	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00644, Pf02877, Pf05406"	"10038"	"ENSG00000129484"	"PARP2"	"hsa:10038; Q8TEU4; Q9NUV2; Q9UGN5; Q9UMR4; Q9Y6C8"	"NAD+ biosynthetic pathways; Base excision repair; Peroxiredoxin 2 induced ovarian failure; DNA repair pathways, full network"	"Formation of Incision Complex in GG-NER; DNA Damage Recognition in GG-NER; Dual Incision in GG-NER; HDR through MMEJ (alt-NHEJ); POLB-Dependent Long Patch Base Excision Repair"	"9"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15796"	"Mothers against decapentaplegic homolog 2 OS=Homo sapiens OX=9606 GN=SMAD2 PE=1 SV=1"	"5"	"1"	"1"	"1"	"467"	"52.3"	"6.58"	""	"4.41"	""	"1"	"cell-cell signaling;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf03165, Pf03166"	"4087"	"ENSG00000175387"	"SMAD2"	"hsa:4087; Q15796"	"Cell cycle; AGE/RAGE pathway; Endoderm differentiation; Mesodermal commitment pathway; Extracellular vesicle-mediated signaling in recipient cells; Mesodermal commitment pathway; Hypothesized pathways in pathogenesis of cardiovascular disease; Tgif disruption of Shh signaling; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition; Canonical and non-canonical TGF-B signaling; Chromosomal and microsatellite instability in colorectal cancer ; Epithelial to mesenchymal transition in colorectal cancer; Pancreatic adenocarcinoma pathway; Neovascularisation processes; Envelope proteins and their potential roles in EDMD physiopathology; Hippo signaling regulation pathways; Hepatitis B infection; TGF-beta receptor signaling in skeletal dysplasias; Regucalcin in proximal tubule epithelial kidney cells; Overlap between signal transduction pathways contributing to LMNA laminopathies; LDLRAD4 and what we know about it; Neuroinflammation and glutamatergic signaling; CCL18 signaling pathway; Progeria-associated lipodystrophy; Th17 cell differentiation pathway; GDNF signaling; Inflammatory bowel disease signaling; A network map of Macrophage-stimulating protein (MSP) signaling; TGF-beta receptor signaling"	"Ub-specific processing proteases; SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Downregulation of TGF-beta receptor signaling; Downregulation of SMAD2/3:SMAD4 transcriptional activity; Formation of axial mesoderm; FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes; Signaling by NODAL; FOXO-mediated transcription of cell cycle genes; Germ layer formation at gastrulation; Formation of definitive endoderm; Transcriptional regulation of pluripotent stem cells; Signaling by Activin; SMAD2/3 Phosphorylation Motif Mutants in Cancer; TGFBR1 KD Mutants in Cancer; SMAD4 MH2 Domain Mutants in Cancer; SMAD2/3 MH2 Domain Mutants in Cancer"	"47"	"0"	"8.2"	"6.7"	"14.4"	"14.7"	"9.9"	"14.5"	"24.6"	"30.3"	"37.7"	"67.1"	"92.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13098"	"COP9 signalosome complex subunit 1 OS=Homo sapiens OX=9606 GN=GPS1 PE=1 SV=4"	"4"	"1"	"2"	"1"	"491"	"55.5"	"6.74"	"535.19"	"4.41"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf01399, Pf10602"	"2873"	"ENSG00000169727"	"GPS1"	"hsa:2873; Q13098; Q8NA10; Q9BWL1"	""	"Neddylation; Cargo recognition for clathrin-mediated endocytosis; Formation of TC-NER Pre-Incision Complex; RHOBTB1 GTPase cycle; DNA Damage Recognition in GG-NER"	"5"	"0"	"12.5"	"9.2"	"17.2"	"17.2"	"11.2"	"19.2"	"28.7"	"26.6"	"17.3"	"28.7"	"34.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WUQ7"	"Cactin OS=Homo sapiens OX=9606 GN=CACTIN PE=1 SV=3"	"3"	"1"	"2"	"1"	"758"	"88.6"	"9.14"	"440.04"	"4.40"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf09732, Pf10312"	"58509"	"ENSG00000105298"	"CACTIN"	"A6NNA9; A9UL12; hsa:58509; O75229; Q7LE08; Q8WUQ7; Q9BTA6; Q9Y5A4"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"11.0"	"11.3"	"15.1"	"13.4"	"18.6"	"18.6"	"23.9"	"25.2"	"21.0"	"28.1"	"37.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92878"	"DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1"	"1"	"2"	"4"	"2"	"1312"	"153.8"	"6.89"	"356.66"	"4.40"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04423, Pf13476, Pf13558"	"10111"	"ENSG00000113522"	"RAD50"	"B9EGF5; hsa:10111; O43254; Q6GMT7; Q6P5X3; Q92878; Q9UP86"	"miRNA regulation of DNA damage response; Homologous recombination; DDX1 as a regulatory component of the Drosha microprocessor; ATM signaling in development and disease ; Breast cancer pathway; Joubert syndrome; DNA repair pathways, full network; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; DNA damage response"	"Sensing of DNA Double Strand Breaks; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Resolution of D-loop Structures through Holliday Junction Intermediates; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; Meiotic recombination; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; DNA Damage/Telomere Stress Induced Senescence; Nonhomologous End-Joining (NHEJ); HDR through MMEJ (alt-NHEJ)"	"29"	"0"	"318.7"	"171.4"	"261.4"	"246.6"	"294.6"	"220.6"	"436.8"	"407.4"	"333.0"	"428.7"	"548.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86XH1"	"Dynein regulatory complex protein 11 OS=Homo sapiens OX=9606 GN=IQCA1 PE=2 SV=1"	"1"	"1"	"3"	"1"	"822"	"95.3"	"9.47"	"249.64"	"4.39"	"1"	"1"	"cell organization and biogenesis"	"cytoskeleton;other cell component"	"other molecular function"	"Pf00004"	"79781"	"ENSG00000132321"	"IQCA1"	"B4DFH9; E7EWQ0; hsa:79781; Q4G164; Q53R37; Q53RV3; Q86XH1; Q96NS7; Q9H680"	"2q37 copy number variation syndrome"	""	"1"	"0"	"125.1"	"92.0"	"109.5"	"117.7"	"124.7"	"136.0"	"263.4"	"236.8"	"226.6"	"334.9"	"475.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99959"	"Plakophilin-2 OS=Homo sapiens OX=9606 GN=PKP2 PE=1 SV=2"	"2"	"2"	"3"	"2"	"881"	"97.4"	"9.33"	"683.07"	"4.36"	"2"	"1"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00514"	"5318"	"ENSG00000057294"	"PKP2"	"A0AV37; B8QFA1; B8QGS6; B8QGS7; D3DUW9; hsa:5318; Q4VC01; Q99959; Q99960"	"Arrhythmogenic right ventricular cardiomyopathy; Epithelial to mesenchymal transition in colorectal cancer"	"Formation of the cornified envelope"	"4"	"0"	"95.6"	"68.8"	"81.7"	"74.4"	"93.1"	"79.0"	"106.4"	"96.9"	"91.8"	"113.0"	"177.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92552"	"28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3"	"10"	"4"	"5"	"4"	"414"	"47.6"	"6.18"	"962.31"	"4.36"	"3"	"2"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf10037"	"23107"	"ENSG00000113048"	"MRPS27"	"B4DRT2; hsa:23107; Q6P1S1; Q92552"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"134.9"	"76.6"	"114.4"	"97.3"	"107.1"	"121.9"	"204.2"	"168.7"	"127.6"	"195.5"	"250.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BPW8"	"Protein NipSnap homolog 1 OS=Homo sapiens OX=9606 GN=NIPSNAP1 PE=1 SV=1"	"7"	"2"	"3"	"2"	"284"	"33.3"	"9.31"	"234.71"	"4.35"	"1"	"2"	"other biological processes"	"plasma membrane;other membranes;mitochondrion"	"other molecular function"	"Pf07978"	"8508"	"ENSG00000184117"	"NIPSNAP1"	"B2RAY3; hsa:8508; O43800; Q9BPW8"	""	""	"0"	"0"	"46.0"	"30.9"	"42.3"	"38.3"	"43.1"	"53.1"	"139.4"	"136.2"	"105.5"	"136.1"	"144.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IUH3"	"RNA-binding protein 45 OS=Homo sapiens OX=9606 GN=RBM45 PE=1 SV=1"	"3"	"2"	"4"	"2"	"476"	"53.5"	"7.17"	"527.25"	"4.34"	"2"	"2"	"developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"129831"	"ENSG00000155636"	"RBM45"	"hsa:129831; Q6NYL0; Q8IUH3; Q8NFC9"	""	""	"0"	"0"	"142.5"	"79.9"	"100.7"	"107.7"	"109.3"	"133.4"	"364.7"	"355.4"	"254.9"	"334.5"	"436.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94826"	"Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1"	"3"	"2"	"3"	"2"	"608"	"67.4"	"7.12"	"727.62"	"4.33"	"2"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00515, Pf13181"	"9868"	"ENSG00000154174"	"TOMM70"	"D3DN48; hsa:9868; O94826"	"Mitochondrial immune response to SARS-CoV-2; SARS-CoV-2 B.1.1.7 variant antagonises innate immune activation; SARS-CoV-2 mitochondrial chronic oxidative stress and endothelial dysfunction"	"Ub-specific processing proteases; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Mitochondrial protein import; DDX58/IFIH1-mediated induction of interferon-alpha/beta; SARS-CoV-1 activates/modulates innate immune responses; PINK1-PRKN Mediated Mitophagy"	"9"	"0"	"88.1"	"43.0"	"75.6"	"83.9"	"89.2"	"98.2"	"175.5"	"165.9"	"116.1"	"212.5"	"289.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBW8"	"COP9 signalosome complex subunit 7a OS=Homo sapiens OX=9606 GN=COPS7A PE=1 SV=1"	"5"	"1"	"2"	"1"	"275"	"30.3"	"8.22"	"411.73"	"4.29"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf01399, Pf18392"	"50813"	"ENSG00000111652"	"COPS7A"	"A8K9A6; hsa:50813; Q9NVX3; Q9UBW8; Q9UJW4"	"Ciliary landscape"	"Cargo recognition for clathrin-mediated endocytosis; Neddylation; Formation of TC-NER Pre-Incision Complex; DNA Damage Recognition in GG-NER"	"5"	"0"	"10.3"	"10.9"	"13.3"	"12.2"	"15.6"	"18.2"	"19.0"	"20.2"	"15.4"	"24.1"	"34.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96QZ7"	"Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 OS=Homo sapiens OX=9606 GN=MAGI1 PE=1 SV=3"	"1"	"1"	"2"	"1"	"1491"	"164.5"	"7.58"	"377.12"	"4.27"	"1"	"1"	"cell adhesion;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00397, Pf00595, Pf00625, Pf16663, Pf16666"	"9223"	"ENSG00000151276; ENSG00000282956"	"MAGI1"	"A8K188; hsa:9223; O00309; O43863; O75085; Q96QZ7; Q96QZ8; Q96QZ9"	"Pathways affected in adenoid cystic carcinoma"	""	"1"	"0"	"11.8"	"7.6"	"12.8"	"5.5"	"7.7"	"12.6"	"21.0"	"18.0"	"11.8"	"21.3"	"34.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14571"	"Inositol 1,4,5-trisphosphate receptor type 2 OS=Homo sapiens OX=9606 GN=ITPR2 PE=1 SV=2"	"1"	"4"	"6"	"2"	"2701"	"307.9"	"6.43"	"1050.55"	"4.27"	"4"	"2"	"stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00520, Pf01365, Pf02815, Pf08454, Pf08709"	"3709"	"ENSG00000123104"	"ITPR2"	"hsa:3709; O94773; Q14571"	"Alzheimer's disease and miRNA effects; Myometrial relaxation and contraction pathways; Vitamin D-sensitive calcium signaling in depression; Thyroid hormones production and peripheral downstream signaling effects; Alzheimer's disease; GDNF signaling; Calcium regulation in cardiac cells"	"Role of phospholipids in phagocytosis; FCERI mediated Ca+2 mobilization; FCGR3A-mediated IL10 synthesis; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Ion homeostasis; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Ca2+ pathway; VEGFR2 mediated cell proliferation; Elevation of cytosolic Ca2+ levels; PLC beta mediated events; DAG and IP3 signaling; CLEC7A (Dectin-1) induces NFAT activation; Effects of PIP2 hydrolysis"	"21"	"2"	"455.6"	"261.4"	"338.1"	"254.7"	"364.1"	"305.4"	"1084.7"	"1025.8"	"727.3"	"1173.2"	"1627.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P56159"	"GDNF family receptor alpha-1 OS=Homo sapiens OX=9606 GN=GFRA1 PE=1 SV=2"	"6"	"1"	"1"	"1"	"465"	"51.4"	"7.91"	""	"4.24"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf02351"	"2674"	"ENSG00000151892"	"GFRA1"	"A8KA21; hsa:2674; O15507; O43912; P56159"	"Exercise-induced circadian regulation; GDNF/RET signaling axis; Development of ureteric collection system; GDNF signaling"	"NCAM1 interactions; RET signaling; RAF/MAP kinase cascade"	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94776"	"Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"668"	"75.0"	"9.66"	"461.62"	"4.24"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00320, Pf01426, Pf01448, Pf17226"	"9219"	"ENSG00000149480"	"MTA2"	"hsa:9219; O94776; Q68DB1; Q9UQB5"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"Potential therapeutics for SARS; Regulation of PTEN gene transcription; HDACs deacetylate histones; RNA Polymerase I Transcription Initiation; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of TP53 Activity through Acetylation"	"7"	"0"	"59.1"	"30.4"	"54.8"	"61.6"	"52.3"	"62.6"	"91.0"	"86.7"	"63.0"	"104.1"	"136.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q3SYG4"	"Protein PTHB1 OS=Homo sapiens OX=9606 GN=BBS9 PE=1 SV=1"	"2"	"1"	"2"	"1"	"887"	"99.2"	"5.55"	"420.69"	"4.23"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	""	"Pf14727, Pf14728"	"27241"	"ENSG00000122507"	"BBS9"	"E9PDC9; hsa:27241; P78514; Q3SYG4; Q7KYS6; Q7KYS7; Q8N570; Q99844; Q99854; Q9Y699; Q9Y6A0"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies; Bardet-Biedl syndrome"	"BBSome-mediated cargo-targeting to cilium"	"6"	"0"	"11.1"	"7.2"	"11.9"	"14.2"	"13.7"	"13.8"	"26.0"	"39.0"	"55.7"	"105.3"	"140.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95785"	"Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2"	"1"	"1"	"2"	"1"	"1651"	"178.6"	"6.86"	"575.76"	"4.23"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	""	"58525"	"ENSG00000011451"	"WIZ"	"B3KVH1; B7ZM82; hsa:58525; M0QY21; O95785; Q4G0E0; Q6P6B0; Q6ZN24; Q7LDY6; Q7LDZ1; Q96IG5; Q96SQ6; Q9BUR8; Q9NPT1"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13416"	"Origin recognition complex subunit 2 OS=Homo sapiens OX=9606 GN=ORC2 PE=1 SV=2"	"2"	"2"	"3"	"2"	"577"	"65.9"	"6.51"	"266.45"	"4.22"	"1"	"2"	"DNA metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity"	"Pf04084"	"4999"	"ENSG00000115942"	"ORC2"	"hsa:4999; Q13204; Q13416; Q53TX5"	"Cell cycle; G1 to S cell cycle control; DNA replication"	"Activation of the pre-replicative complex; Orc1 removal from chromatin; Activation of ATR in response to replication stress; E2F-enabled inhibition of pre-replication complex formation; Assembly of the ORC complex at the origin of replication; CDC6 association with the ORC:origin complex"	"10"	"0"	"198.7"	"127.9"	"199.1"	"156.2"	"216.2"	"192.7"	"435.9"	"406.7"	"282.5"	"421.8"	"603.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BTD8"	"RNA-binding protein 42 OS=Homo sapiens OX=9606 GN=RBM42 PE=1 SV=1"	"4"	"2"	"4"	"2"	"480"	"50.4"	"9.63"	"500.74"	"4.21"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"79171"	"ENSG00000126254"	"RBM42"	"hsa:79171; O00320; Q8N5R7; Q9BTD8; Q9BU66"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"115.8"	"73.3"	"89.1"	"89.3"	"115.8"	"112.7"	"220.7"	"199.4"	"128.1"	"242.9"	"291.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13889"	"General transcription factor IIH subunit 3 OS=Homo sapiens OX=9606 GN=GTF2H3 PE=1 SV=2"	"6"	"1"	"2"	"1"	"308"	"34.4"	"7.02"	"416.71"	"4.21"	"1"	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf03850"	"2967"	"ENSG00000111358"	"GTF2H3"	"B2R819; B4DNZ6; hsa:2967; Q13889; Q7L0G0; Q96AT7"	"Eukaryotic transcription initiation; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"RNA Polymerase II Pre-transcription Events; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; TP53 Regulates Transcription of DNA Repair Genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Dual Incision in GG-NER"	"33"	"0"	"4.7"	"4.1"	"4.9"	"4.0"	"3.7"	"3.9"	"10.3"	"36.2"	"37.0"	"54.7"	"60.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UHV9"	"Prefoldin subunit 2 OS=Homo sapiens OX=9606 GN=PFDN2 PE=1 SV=1"	"8"	"1"	"2"	"1"	"154"	"16.6"	"6.58"	"318.16"	"4.21"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01920"	"5202"	"ENSG00000143256"	"PFDN2"	"hsa:5202; Q9P0P7; Q9UHV9; Q9UN05"	"Cellular proteostasis"	"Prefoldin mediated transfer of substrate  to CCT/TriC"	"2"	"0"	"48.4"	"27.1"	"41.6"	"41.2"	"35.9"	"43.8"	"81.3"	"73.7"	"55.7"	"83.1"	"122.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75489"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS3 PE=1 SV=1"	"11"	"2"	"3"	"2"	"264"	"30.2"	"7.50"	"1041.39"	"4.21"	"2"	"1"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion;nucleus"	"transporter activity;other molecular function"	"Pf00329"	"4722"	"ENSG00000213619; ENSG00000285387"	"NDUFS3"	"B2R9J1; B4DFM8; hsa:4722; O75489; Q9UNQ8"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"RHOG GTPase cycle; Complex I biogenesis"	"6"	"0"	"65.9"	"51.8"	"76.3"	"50.0"	"70.1"	"72.7"	"121.9"	"111.5"	"81.1"	"146.7"	"169.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92759"	"General transcription factor IIH subunit 4 OS=Homo sapiens OX=9606 GN=GTF2H4 PE=1 SV=1"	"3"	"1"	"3"	"1"	"462"	"52.2"	"9.04"	"278.03"	"4.19"	"1"	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03849, Pf18307"	"2968"	"ENSG00000213780; ENSG00000221974; ENSG00000226384; ENSG00000233149; ENSG00000234370; ENSG00000236895"	"GTF2H4"	"B4DTJ5; hsa:2968; Q76KU4; Q92759"	"Eukaryotic transcription initiation; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"NoRC negatively regulates rRNA expression; RNA Polymerase I Promoter Escape; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Dual Incision in GG-NER; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Transcription Termination"	"33"	"0"	"18.9"	"14.5"	"24.7"	"23.1"	"19.4"	"24.0"	"36.0"	"45.4"	"41.9"	"74.3"	"101.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EV2"	"RNA-binding protein 33 OS=Homo sapiens OX=9606 GN=RBM33 PE=1 SV=3"	"2"	"1"	"2"	"1"	"1170"	"129.9"	"6.93"	"606.15"	"4.19"	"1"	"1"	""	""	""	""	"155435"	"ENSG00000184863"	"RBM33"	"A4D244; B5MC24; hsa:155435; Q52LF5; Q75LN9; Q75ML5; Q96EV2; Q9NSV0"	""	""	"0"	"0"	"20.5"	"10.3"	"14.8"	"19.5"	"22.0"	"22.4"	"81.2"	"74.3"	"48.1"	"85.5"	"100.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75792"	"Ribonuclease H2 subunit A OS=Homo sapiens OX=9606 GN=RNASEH2A PE=1 SV=2"	"5"	"1"	"2"	"1"	"299"	"33.4"	"5.25"	"398.85"	"4.18"	"1"	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01351"	"10535"	"ENSG00000104889"	"RNASEH2A"	"B2RCY1; hsa:10535; O75792; Q96F11"	""	""	"0"	"0"	"7.9"	"3.9"	"8.9"	"5.4"	"8.6"	"8.8"	"17.3"	"14.8"	"12.3"	"21.9"	"22.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q05682"	"Caldesmon OS=Homo sapiens OX=9606 GN=CALD1 PE=1 SV=3"	"2"	"2"	"4"	"2"	"793"	"93.2"	"5.66"	"584.73"	"4.18"	"2"	"2"	"cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton"	"cytoskeletal activity;other molecular function"	"Pf02029"	"800"	"ENSG00000122786"	"CALD1"	"A8K0X1; hsa:800; Q05682; Q13978; Q13979; Q14741; Q14742; Q9UD91"	"Myometrial relaxation and contraction pathways"	"Smooth Muscle Contraction"	"2"	"0"	"71.5"	"36.5"	"60.1"	"57.4"	"65.0"	"59.1"	"208.9"	"181.9"	"130.6"	"221.3"	"312.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BUR4"	"Telomerase Cajal body protein 1 OS=Homo sapiens OX=9606 GN=WRAP53 PE=1 SV=1"	"3"	"1"	"2"	"1"	"548"	"59.3"	"4.58"	"417.64"	"4.16"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400"	"55135"	"ENSG00000141499"	"WRAP53"	"B3KPR9; D3DTQ4; hsa:55135; Q08ET9; Q9BUR4; Q9NW09"	""	"Association of TriC/CCT with target proteins during biosynthesis; Telomere Extension By Telomerase"	"2"	"0"	"27.8"	"23.3"	"35.3"	"32.2"	"37.5"	"34.9"	"60.4"	"56.8"	"53.6"	"71.9"	"95.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13526"	"Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 OS=Homo sapiens OX=9606 GN=PIN1 PE=1 SV=1"	"9"	"1"	"2"	"1"	"163"	"18.2"	"8.82"	"414.30"	"4.16"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00397, Pf00639"	"5300"	"ENSG00000127445"	"PIN1"	"A8K4V9; hsa:5300; Q13526; Q53X75"	"Novel intracellular components of RIG-I-like receptor pathway"	"ISG15 antiviral mechanism; RHO GTPases Activate NADPH Oxidases; Regulation of TP53 Activity through Phosphorylation; Negative regulators of DDX58/IFIH1 signaling; PI5P Regulates TP53 Acetylation"	"6"	"0"	"25.6"	"11.6"	"23.9"	"26.8"	"18.2"	"24.3"	"43.6"	"33.9"	"20.1"	"48.6"	"74.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5UIP0"	"Telomere-associated protein RIF1 OS=Homo sapiens OX=9606 GN=RIF1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"2472"	"274.3"	"5.52"	"505.17"	"4.14"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	""	"Pf12231"	"55183"	"ENSG00000080345"	"RIF1"	"A6NC27; C9JBR1; hsa:55183; Q5H9R3; Q5UIP0; Q5UIP2; Q66YK6; Q6PRU2; Q8TE94; Q99772; Q9H830; Q9H9B9; Q9NVP5; Q9Y4R4"	"ATM signaling in development and disease ; 10q11.21q11.23 copy number variation syndrome"	"Nonhomologous End-Joining (NHEJ)"	"3"	"0"	"22.3"	"15.7"	"17.7"	"14.9"	"21.5"	"23.4"	"37.5"	"33.6"	"27.2"	"44.7"	"62.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H2H8"	"Peptidyl-prolyl cis-trans isomerase-like 3 OS=Homo sapiens OX=9606 GN=PPIL3 PE=1 SV=1"	"8"	"1"	"2"	"1"	"161"	"18.1"	"6.79"	"377.22"	"4.14"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00160"	"53938"	"ENSG00000240344"	"PPIL3"	"hsa:53938; Q86WF9; Q96IA9; Q9BXZ1; Q9H2H8"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"28.5"	"14.7"	"20.6"	"16.6"	"19.9"	"23.5"	"55.0"	"59.0"	"44.3"	"67.5"	"120.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25440"	"Bromodomain-containing protein 2 OS=Homo sapiens OX=9606 GN=BRD2 PE=1 SV=2"	"2"	"1"	"2"	"1"	"801"	"88.0"	"9.09"	"402.89"	"4.13"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00439, Pf17035"	"6046"	"ENSG00000204256; ENSG00000215077; ENSG00000234507; ENSG00000234704; ENSG00000235307"	"BRD2"	"A2AAU0; B0S7P0; B1AZT1; hsa:6046; O00699; O00700; P25440; Q15310; Q5STC9; Q63HQ9; Q658Y7; Q6P3U2; Q969U4"	""	"RUNX3 regulates p14-ARF"	"1"	"0"	"4.7"	"4.3"	"4.7"	"6.5"	"4.2"	"8.0"	"9.1"	"13.5"	"10.4"	"25.7"	"45.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60341"	"Lysine-specific histone demethylase 1A OS=Homo sapiens OX=9606 GN=KDM1A PE=1 SV=2"	"2"	"1"	"2"	"1"	"852"	"92.8"	"6.52"	"455.70"	"4.11"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01593, Pf04433"	"23028"	"ENSG00000004487"	"KDM1A"	"A8MWP9; hsa:23028; O60341; Q5TH94; Q5TH95; Q86VT7; Q8IXK4; Q8NDP6; Q8TAZ3; Q96AW4"	"Androgen receptor signaling pathway; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; Thermogenesis; Vitamin D-sensitive calcium signaling in depression; Thyroid hormones production and peripheral downstream signaling effects; Neurogenesis regulation in the olfactory epithelium"	"Estrogen-dependent gene expression; Potential therapeutics for SARS; Regulation of PTEN gene transcription; HDACs deacetylate histones; Factors involved in megakaryocyte development and platelet production; HDMs demethylate histones; NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3"	"14"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P01040"	"Cystatin-A OS=Homo sapiens OX=9606 GN=CSTA PE=1 SV=1"	"12"	"1"	"2"	"1"	"98"	"11.0"	"5.50"	"376.44"	"4.10"	"1"	"1"	"cell adhesion;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;plasma membrane;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00031"	"1475"	"ENSG00000121552"	"CSTA"	"hsa:1475; P01040; Q6IB90"	"8p23.1 copy number variation syndrome"	"Formation of the cornified envelope"	"2"	"0"	"54.8"	"35.7"	"145.8"	"36.3"	"61.7"	"45.4"	"154.0"	"132.9"	"96.9"	"157.5"	"213.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13084"	"39S ribosomal protein L28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL28 PE=1 SV=4"	"11"	"2"	"2"	"2"	"256"	"30.1"	"8.29"	"252.87"	"4.10"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;cytosol;mitochondrion;translational apparatus"	"other molecular function"	"Pf00830"	"10573"	"ENSG00000086504"	"MRPL28"	"B2RCM4; D3DU46; hsa:10573; Q13084; Q4TT39; Q96S26; Q9BQD8; Q9BR04"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"66.4"	"43.3"	"43.1"	"40.6"	"46.0"	"57.1"	"112.1"	"97.6"	"69.1"	"105.8"	"157.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60510"	"Serine/threonine-protein phosphatase 4 catalytic subunit OS=Homo sapiens OX=9606 GN=PPP4C PE=1 SV=1"	"4"	"1"	"2"	"1"	"307"	"35.1"	"5.06"	"347.08"	"4.09"	"1"	"1"	"DNA metabolism;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00149"	"5531"	"ENSG00000149923"	"PPP4C"	"hsa:5531; P33172; P60510"	"16p11.2 proximal deletion syndrome"	"Processing of DNA double-strand break ends"	"2"	"0"	"5.3"	"7.7"	"9.5"	"8.9"	"6.7"	"8.6"	"16.1"	"18.8"	"18.3"	"22.1"	"28.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UDY4"	"DnaJ homolog subfamily B member 4 OS=Homo sapiens OX=9606 GN=DNAJB4 PE=1 SV=1"	"5"	"1"	"2"	"1"	"337"	"37.8"	"8.50"	"326.98"	"4.06"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	"other molecular function"	"Pf00226, Pf01556"	"11080"	"ENSG00000162616"	"DNAJB4"	"B2R824; hsa:11080; Q13431; Q9UDY4"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"4.4"	"0.0"	"4.4"	"4.1"	"7.0"	"4.3"	"47.9"	"52.1"	"31.2"	"51.6"	"50.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95166"	"Gamma-aminobutyric acid receptor-associated protein OS=Homo sapiens OX=9606 GN=GABARAP PE=1 SV=1"	"25"	"2"	"3"	"2"	"117"	"13.9"	"8.79"	"700.23"	"4.04"	"2"	"1"	"cell-cell signaling;cell organization and biogenesis;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf02991"	"11337"	"ENSG00000170296"	"GABARAP"	"hsa:11337; O95166"	"2q37 copy number variation syndrome"	"Macroautophagy; TBC/RABGAPs"	"3"	"0"	"94.0"	"48.2"	"71.2"	"54.2"	"70.2"	"89.0"	"146.3"	"157.2"	"134.3"	"210.1"	"501.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96BZ8"	"Leukocyte receptor cluster member 1 OS=Homo sapiens OX=9606 GN=LENG1 PE=1 SV=1"	"6"	"1"	"2"	"1"	"264"	"30.5"	"9.69"	"425.44"	"4.00"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"14.7"	"10.0"	"10.9"	"10.8"	"19.5"	"14.3"	"44.5"	"33.2"	"30.3"	"45.0"	"51.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H2P0"	"Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1"	"3"	"3"	"4"	"3"	"1102"	"123.5"	"7.34"	"939.13"	"3.97"	"3"	"1"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00046, Pf19627"	"23394"	"ENSG00000101126"	"ADNP"	"E1P5Y2; hsa:23394; O94881; Q5BKU2; Q9H2P0; Q9UG34"	""	""	"0"	"0"	"265.3"	"153.8"	"240.2"	"230.4"	"244.5"	"296.3"	"478.3"	"441.2"	"310.9"	"471.6"	"641.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04181"	"Ornithine aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OAT PE=1 SV=1"	"4"	"1"	"2"	"1"	"439"	"48.5"	"7.03"	"518.52"	"3.96"	"1"	"1"	"other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00202"	"4942"	"ENSG00000065154"	"OAT"	"D3DRF0; hsa:4942; P04181; Q16068; Q16069; Q68CS0; Q6IAV9; Q9UD03"	"Amino acid metabolism; 22q11.2 copy number variation syndrome; Creatine pathway"	"Glutamate and glutamine metabolism"	"4"	"0"	"46.0"	"43.4"	"87.1"	"29.5"	"49.9"	"44.8"	"43.8"	"40.0"	"23.0"	"49.8"	"66.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BYG3"	"MKI67 FHA domain-interacting nucleolar phosphoprotein OS=Homo sapiens OX=9606 GN=NIFK PE=1 SV=1"	"6"	"1"	"2"	"1"	"293"	"34.2"	"9.88"	"394.36"	"3.96"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf12196"	"84365"	"ENSG00000155438"	"NIFK"	"A8K788; hsa:84365; Q8TB66; Q96ED4; Q9BYG3"	""	""	"0"	"0"	"3.9"	"7.8"	"9.4"	"6.4"	"5.6"	"8.2"	"18.6"	"11.9"	"12.4"	"22.1"	"28.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62877"	"E3 ubiquitin-protein ligase RBX1 OS=Homo sapiens OX=9606 GN=RBX1 PE=1 SV=1"	"13"	"1"	"2"	"1"	"108"	"12.3"	"6.96"	"440.36"	"3.95"	"1"	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf12678"	"9978"	"ENSG00000100387"	"RBX1"	"B2RDY1; hsa:9978; P62877; Q8N6Z8; Q9D1S2; Q9WUK9; Q9Y254"	"Cell cycle; Dual hijack model of Vif in HIV infection; Type 2 papillary renal cell carcinoma; NRF2-ARE regulation; Hippo-Merlin signaling dysregulation; 22q11.2 copy number variation syndrome; Nucleotide excision repair; Hijack of ubiquitination by SARS-CoV-2; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; 1p36 copy number variation syndrome"	"Potential therapeutics for SARS; Nuclear events stimulated by ALK signaling in cancer; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; Dual Incision in GG-NER; Antigen processing: Ubiquitination & Proteasome degradation; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Degradation of DVL; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; Orc1 removal from chromatin; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Regulation of BACH1 activity; NOTCH1 Intracellular Domain Regulates Transcription; Formation of TC-NER Pre-Incision Complex; Prolactin receptor signaling; DNA Damage Recognition in GG-NER; Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling"	"46"	"0"	"118.1"	"76.2"	"102.2"	"126.3"	"109.8"	"102.2"	"199.0"	"190.1"	"143.0"	"257.9"	"439.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6M9"	"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 OS=Homo sapiens OX=9606 GN=NDUFB9 PE=1 SV=3"	"12"	"2"	"3"	"2"	"179"	"21.8"	"8.38"	"734.90"	"3.94"	"2"	"1"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity"	"Pf05347"	"4715"	"ENSG00000147684"	"NDUFB9"	"B2R8M6; hsa:4715; Q9UQE8; Q9Y6M9"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial immune response to SARS-CoV-2; Oxidative phosphorylation"	"Complex I biogenesis"	"6"	"0"	"175.5"	"95.0"	"147.8"	"116.5"	"140.3"	"133.2"	"237.2"	"186.1"	"139.5"	"273.9"	"356.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96H20"	"Vacuolar-sorting protein SNF8 OS=Homo sapiens OX=9606 GN=SNF8 PE=1 SV=1"	"3"	"1"	"1"	"1"	"258"	"28.8"	"6.65"	""	"3.94"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf04157"	"11267"	"ENSG00000159210"	"SNF8"	"hsa:11267; Q8IXY3; Q96H20; Q9UN50"	""	"HCMV Late Events; Endosomal Sorting Complex Required For Transport (ESCRT)"	"2"	"0"	"20.7"	"15.8"	"18.6"	"21.6"	"20.4"	"24.5"	"51.8"	"106.9"	"134.3"	"253.4"	"572.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75909"	"Cyclin-K OS=Homo sapiens OX=9606 GN=CCNK PE=1 SV=2"	"3"	"1"	"2"	"1"	"580"	"64.2"	"8.41"	"394.90"	"3.93"	"1"	"1"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00134"	"8812"	"ENSG00000090061"	"CCNK"	"hsa:8812; O75909; Q59FT6; Q86U16; Q96B63; Q9NNY9"	"Male infertility"	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes"	"10"	"0"	"26.8"	"13.9"	"19.3"	"17.8"	"18.8"	"16.3"	"45.7"	"43.7"	"28.9"	"61.4"	"96.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NEF9"	"Serum response factor-binding protein 1 OS=Homo sapiens OX=9606 GN=SRFBP1 PE=1 SV=1"	"3"	"1"	"2"	"1"	"429"	"48.6"	"9.58"	"407.07"	"3.93"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf09073"	"153443"	"ENSG00000151304"	"SRFBP1"	"hsa:153443; Q5QFI2; Q8NEF9; Q96AH4; Q96DK2"	""	""	"0"	"0"	"8.2"	"5.5"	"4.5"	"8.0"	"10.4"	"7.9"	"59.8"	"39.0"	"36.5"	"50.8"	"60.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P78346"	"Ribonuclease P protein subunit p30 OS=Homo sapiens OX=9606 GN=RPP30 PE=1 SV=1"	"5"	"1"	"2"	"1"	"268"	"29.3"	"8.91"	"382.78"	"3.92"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01876"	"10556"	"ENSG00000148688"	"RPP30"	"B2R799; E9PB02; hsa:10556; P78346"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; tRNA processing in the nucleus"	"2"	"0"	"24.1"	"12.4"	"18.9"	"16.5"	"20.3"	"18.5"	"44.0"	"46.2"	"35.2"	"62.5"	"86.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IYB8"	"ATP-dependent RNA helicase SUPV3L1, mitochondrial OS=Homo sapiens OX=9606 GN=SUPV3L1 PE=1 SV=1"	"2"	"1"	"2"	"1"	"786"	"87.9"	"7.99"	"418.92"	"3.92"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cytoplasmic organelle"	"nucleic acid binding activity;other molecular function"	"Pf00271, Pf12513, Pf18114, Pf18147"	"6832"	"ENSG00000156502"	"SUPV3L1"	"A8K301; hsa:6832; O43630; Q8IYB8"	""	""	"0"	"0"	"14.0"	"8.6"	"16.1"	"13.4"	"14.9"	"17.1"	"43.2"	"53.2"	"40.5"	"60.5"	"72.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NYB0"	"Telomeric repeat-binding factor 2-interacting protein 1 OS=Homo sapiens OX=9606 GN=TERF2IP PE=1 SV=1"	"5"	"1"	"2"	"1"	"399"	"44.2"	"4.73"	"388.19"	"3.92"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf08914, Pf11626, Pf16589"	"54386"	"ENSG00000166848"	"TERF2IP"	"B4DQN4; hsa:54386; Q4W4Y2; Q8WYZ3; Q9NWR2; Q9NYB0"	"Splicing factor NOVA regulated synaptic proteins; SARS-CoV-2 mitochondrial chronic oxidative stress and endothelial dysfunction"	"Meiotic synapsis; Telomere Extension By Telomerase; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; Packaging Of Telomere Ends; DNA Damage/Telomere Stress Induced Senescence; Polymerase switching on the C-strand of the telomere; Telomere C-strand synthesis initiation; Removal of the Flap Intermediate from the C-strand"	"16"	"0"	"21.6"	"7.7"	"18.9"	"23.1"	"21.8"	"21.4"	"49.7"	"43.5"	"29.6"	"52.0"	"64.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WVM8"	"Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4"	"2"	"1"	"2"	"1"	"642"	"72.3"	"6.27"	"365.75"	"3.89"	"1"	"1"	"stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi"	"other molecular function"	"Pf00995"	"23256"	"ENSG00000092108"	"SCFD1"	"A8K2Z5; B7Z4U7; B7Z594; hsa:23256; O60754; O94990; Q7Z529; Q8WVM8; Q9BZI3; Q9UNL3; Q9Y6A8"	""	"RHOA GTPase cycle; COPII-mediated vesicle transport"	"2"	"0"	"34.0"	"17.2"	"29.1"	"23.1"	"27.7"	"22.0"	"37.9"	"37.5"	"32.0"	"55.6"	"60.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12694"	"2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=BCKDHA PE=1 SV=2"	"3"	"1"	"2"	"1"	"445"	"50.4"	"8.27"	"451.87"	"3.89"	"1"	"1"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00676"	"593"	"ENSG00000248098"	"BCKDHA"	"B4DP47; E7EW46; hsa:593; P12694; Q16034; Q16472"	"Lipid metabolism pathway"	"Glyoxylate metabolism and glycine degradation; Branched-chain amino acid catabolism"	"3"	"0"	"85.5"	"69.7"	"92.3"	"80.9"	"97.7"	"73.5"	"125.3"	"136.0"	"109.2"	"136.3"	"129.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07108"	"Acyl-CoA-binding protein OS=Homo sapiens OX=9606 GN=DBI PE=1 SV=2"	"23"	"1"	"2"	"1"	"87"	"10.0"	"6.57"	"557.43"	"3.88"	"1"	"1"	"other metabolic processes;other biological processes"	"ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00887"	"1622"	"ENSG00000155368"	"DBI"	"B8ZWD2; B8ZWD6; B8ZWD7; hsa:1622; P07108; P08869; Q4VWZ6; Q53SQ7; Q6IB48; Q9UCI8"	"Sterol regulatory element-binding proteins (SREBP) signaling; PPAR-alpha pathway; Nuclear receptors meta-pathway; PPAR signaling pathway; Fatty acid transporters"	"Mitochondrial Fatty Acid Beta-Oxidation"	"6"	"0"	"24.5"	"17.9"	"35.7"	"11.4"	"27.9"	"30.8"	"54.6"	"38.7"	"36.1"	"59.5"	"74.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N5M1"	"ATP synthase mitochondrial F1 complex assembly factor 2 OS=Homo sapiens OX=9606 GN=ATPAF2 PE=1 SV=1"	"8"	"1"	"1"	"1"	"289"	"32.8"	"7.09"	""	"3.85"	""	"1"	"cell organization and biogenesis"	"cytosol;mitochondrion;nucleus"	""	"Pf07542"	"91647"	"ENSG00000171953"	"ATPAF2"	"A6NDE5; A8K2J2; hsa:91647; Q6XYC7; Q8N5M1"	"7q11.23 copy number variation syndrome; Smith-Magenis and Potocki-Lupski syndrome copy number variation"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16540"	"39S ribosomal protein L23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL23 PE=1 SV=1"	"14"	"1"	"1"	"1"	"153"	"17.8"	"9.69"	""	"3.84"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00276"	"6150"	"ENSG00000214026; ENSG00000288141"	"MRPL23"	"A8MT29; hsa:6150; Q16540; Q96Q71"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"19.9"	"10.9"	"21.8"	"20.7"	"16.1"	"25.8"	"37.0"	"21.5"	"16.0"	"32.7"	"54.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60645"	"Exocyst complex component 3 OS=Homo sapiens OX=9606 GN=EXOC3 PE=1 SV=3"	"2"	"1"	"2"	"1"	"745"	"85.5"	"6.29"	"475.56"	"3.84"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf06046"	"11336"	"ENSG00000180104"	"EXOC3"	"hsa:11336; O60645; Q6P2E8; Q8TEN6; Q8WUW0; Q96DI4"	"Ciliary landscape"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"4"	"0"	"16.8"	"15.7"	"24.8"	"22.1"	"24.3"	"25.3"	"42.6"	"48.7"	"58.2"	"102.1"	"129.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96GC5"	"39S ribosomal protein L48, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL48 PE=1 SV=2"	"5"	"1"	"2"	"1"	"212"	"23.9"	"8.98"	"425.12"	"3.83"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	""	"Pf00338"	"51642"	"ENSG00000175581"	"MRPL48"	"B4DN34; hsa:51642; Q49AK7; Q4U2Q4; Q96GC5; Q9P091; Q9Y5J0"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"24.1"	"14.1"	"19.7"	"21.2"	"14.8"	"20.7"	"51.0"	"45.0"	"31.1"	"53.4"	"74.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N3E9"	"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 OS=Homo sapiens OX=9606 GN=PLCD3 PE=1 SV=3"	"3"	"1"	"1"	"1"	"789"	"89.2"	"6.98"	""	"3.82"	""	"1"	"other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	"other molecular function"	"Pf00168, Pf00387, Pf00388, Pf14788"	"113026"	"ENSG00000161714"	"PLCD3"	"hsa:113026; Q8N3E9; Q8TEC1; Q8TF37; Q96FL6"	"GPR40 pathway; Resistin as a regulator of inflammation"	"Synthesis of IP3 and IP4 in the cytosol"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NR12"	"PDZ and LIM domain protein 7 OS=Homo sapiens OX=9606 GN=PDLIM7 PE=1 SV=1"	"3"	"1"	"2"	"1"	"457"	"49.8"	"8.41"	"399.04"	"3.82"	"1"	"1"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412, Pf00595"	"9260"	"ENSG00000196923"	"PDLIM7"	"hsa:9260; Q14250; Q5XG82; Q6NVZ5; Q96C91; Q9BXB8; Q9BXB9; Q9NR12"	"Ebstein-Barr virus LMP1 signaling; GDNF signaling; 5q35 copy number variation"	"RET signaling"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92733"	"Proline-rich protein PRCC OS=Homo sapiens OX=9606 GN=PRCC PE=1 SV=1"	"5"	"2"	"3"	"2"	"491"	"52.4"	"5.10"	"662.12"	"3.81"	"2"	"1"	"cell cycle OR cell proliferation;other biological processes"	"nucleus"	""	"Pf10253"	"5546"	"ENSG00000143294"	"PRCC"	"A8K1F7; hsa:5546; O00665; O00724; Q5SZ06; Q92733"	"Type 2 papillary renal cell carcinoma; IL-18 signaling pathway"	"mRNA Splicing - Major Pathway"	"3"	"0"	"183.0"	"88.8"	"145.0"	"156.3"	"143.5"	"177.4"	"475.8"	"406.2"	"305.3"	"444.8"	"625.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30533"	"Alpha-2-macroglobulin receptor-associated protein OS=Homo sapiens OX=9606 GN=LRPAP1 PE=1 SV=1"	"4"	"1"	"2"	"1"	"357"	"41.4"	"8.78"	"356.28"	"3.80"	"1"	"1"	"transport;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf06400, Pf06401"	"4043"	"ENSG00000163956"	"LRPAP1"	"D3DVR9; hsa:4043; P30533; Q2M310; Q53HQ3; Q53HS6"	"Cholesterol metabolism"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48556"	"26S proteasome non-ATPase regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMD8 PE=1 SV=2"	"4"	"1"	"2"	"1"	"350"	"39.6"	"9.70"	"424.89"	"3.78"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf10075"	"5714"	"ENSG00000099341"	"PSMD8"	"B4DX18; hsa:5714; P48556; Q6P1L7"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"Regulation of PTEN stability and activity; FCERI mediated NF-kB activation; Downstream TCR signaling; Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Regulation of expression of SLITs and ROBOs; Degradation of beta-catenin by the destruction complex; Ub-specific processing proteases; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"64"	"0"	"19.3"	"13.4"	"16.7"	"14.5"	"20.4"	"18.4"	"31.7"	"37.7"	"25.4"	"33.9"	"55.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61077"	"Ubiquitin-conjugating enzyme E2 D3 OS=Homo sapiens OX=9606 GN=UBE2D3 PE=1 SV=1"	"16"	"1"	"1"	"1"	"147"	"16.7"	"7.80"	""	"3.78"	""	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00179"	"7323"	"ENSG00000109332"	"UBE2D3"	"A6NJ93; A6NJB1; A6NM99; hsa:7323; P47986; P61077; Q6IB88; Q6NXS4; Q8N924"	"Proteasome degradation"	"Antigen processing: Ubiquitination & Proteasome degradation; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Neddylation; E3 ubiquitin ligases ubiquitinate target proteins; Peroxisomal protein import; IKK complex recruitment mediated by RIP1; Signaling by BMP; Inactivation of CSF3 (G-CSF) signaling; TICAM1, RIP1-mediated IKK complex recruitment; Regulation of TNFR1 signaling; Negative regulators of DDX58/IFIH1 signaling; Downregulation of SMAD2/3:SMAD4 transcriptional activity"	"13"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9C0K7"	"STE20-related kinase adapter protein beta OS=Homo sapiens OX=9606 GN=STRADB PE=1 SV=1"	"5"	"1"	"1"	"1"	"418"	"47.0"	"7.01"	""	"3.77"	""	"1"	"cell cycle OR cell proliferation;stress response;transport;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00069"	"55437"	"ENSG00000082146"	"STRADB"	"hsa:55437; Q5BKY7; Q9C0K7; Q9P1L0"	"AMP-activated protein kinase signaling; mir-124 predicted interactions with cell cycle and differentiation"	"Energy dependent regulation of mTOR by LKB1-AMPK"	"3"	"0"	"4.7"	"0.0"	"7.1"	"7.9"	"0.0"	"6.8"	"10.8"	"12.8"	"14.0"	"23.7"	"27.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60604"	"Ubiquitin-conjugating enzyme E2 G2 OS=Homo sapiens OX=9606 GN=UBE2G2 PE=1 SV=1"	"15"	"1"	"1"	"1"	"165"	"18.6"	"4.70"	""	"3.77"	""	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf00179"	"7327"	"ENSG00000184787"	"UBE2G2"	"A6NMQ7; A8K3L4; D3DSL7; hsa:7327; P56554; P60604"	"Parkin-ubiquitin proteasomal system pathway; Parkinson's disease pathway"	"Antigen processing: Ubiquitination & Proteasome degradation; Synthesis of active ubiquitin: roles of E1 and E2 enzymes"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60684"	"Importin subunit alpha-7 OS=Homo sapiens OX=9606 GN=KPNA6 PE=1 SV=1"	"5"	"3"	"4"	"3"	"536"	"60.0"	"4.98"	"920.01"	"3.76"	"3"	"1"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf01749, Pf16186"	"23633"	"ENSG00000025800"	"KPNA6"	"B2RDC7; D3DPP5; hsa:23633; O60684; Q5VVU3"	""	"Assembly of the ORC complex at the origin of replication"	"1"	"0"	"189.5"	"108.6"	"177.1"	"170.4"	"180.8"	"181.3"	"377.3"	"386.2"	"311.0"	"422.7"	"492.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H2W6"	"39S ribosomal protein L46, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL46 PE=1 SV=1"	"8"	"2"	"3"	"2"	"279"	"31.7"	"7.05"	"631.66"	"3.75"	"2"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf11788"	"26589"	"ENSG00000259494"	"MRPL46"	"B2RD75; hsa:26589; Q9H2W6; Q9HBU8"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"203.0"	"109.6"	"163.3"	"200.9"	"195.6"	"205.8"	"402.5"	"366.5"	"250.4"	"402.0"	"566.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRT2"	"Ubiquinol-cytochrome-c reductase complex assembly factor 2 OS=Homo sapiens OX=9606 GN=UQCC2 PE=1 SV=1"	"15"	"2"	"3"	"2"	"126"	"14.9"	"7.37"	"580.19"	"3.75"	"2"	"1"	"cell organization and biogenesis;other biological processes"	"other membranes;mitochondrion;nucleus"	""	"Pf20180"	"84300"	"ENSG00000137288"	"UQCC2"	"B2R4I0; hsa:84300; Q9BRT2"	"Mitochondrial complex III assembly"	""	"1"	"0"	"100.1"	"37.6"	"65.8"	"66.2"	"82.8"	"82.5"	"199.3"	"223.2"	"177.4"	"283.0"	"439.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H0W8"	"Protein SMG9 OS=Homo sapiens OX=9606 GN=SMG9 PE=1 SV=1"	"3"	"1"	"2"	"1"	"520"	"57.6"	"7.01"	"354.95"	"3.75"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes"	"cytosol"	"other molecular function"	"Pf10220"	"56006"	"ENSG00000105771"	"SMG9"	"hsa:56006; O60429; Q9H0W8; Q9H9A9"	""	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62891"	"60S ribosomal protein L39 OS=Homo sapiens OX=9606 GN=RPL39 PE=1 SV=2"	"20"	"1"	"2"	"1"	"51"	"6.4"	"12.56"	"400.58"	"3.74"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"non-structural extracellular;cytosol;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00832"	"6170"	"ENSG00000198918"	"RPL39"	"hsa:6170; P02404; P39025; P62891; Q9BYF2"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"34.3"	"27.3"	"39.2"	"29.2"	"35.0"	"34.7"	"134.8"	"120.1"	"76.8"	"138.7"	"143.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96DE5"	"Anaphase-promoting complex subunit 16 OS=Homo sapiens OX=9606 GN=ANAPC16 PE=1 SV=1"	"14"	"1"	"2"	"1"	"110"	"11.7"	"4.97"	"375.29"	"3.71"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf17256"	"119504"	"ENSG00000166295"	"ANAPC16"	"hsa:119504; Q96DE5"	""	"APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Separation of Sister Chromatids; CDK-mediated phosphorylation and removal of Cdc6; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Senescence-Associated Secretory Phenotype (SASP); Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of Cyclin B; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; Regulation of APC/C activators between G1/S and early anaphase; Phosphorylation of the APC/C; APC-Cdc20 mediated degradation of Nek2A; Transcriptional Regulation by VENTX; Aberrant regulation of mitotic exit in cancer due to RB1 defects"	"17"	"0"	"27.6"	"11.9"	"30.7"	"29.8"	"34.2"	"35.5"	"57.2"	"56.5"	"31.9"	"67.6"	"91.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2A7"	"Nck-associated protein 1 OS=Homo sapiens OX=9606 GN=NCKAP1 PE=1 SV=1"	"2"	"2"	"3"	"2"	"1128"	"128.7"	"6.62"	"585.65"	"3.66"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	""	"Pf09735"	"10787"	"ENSG00000061676"	"NCKAP1"	"hsa:10787; O60329; Q53QN5; Q53S94; Q53Y35; Q9Y2A7"	"Exercise-induced circadian regulation; Regulation of actin cytoskeleton"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RAC1 GTPase cycle; RHO GTPases Activate WASPs and WAVEs; RAC2 GTPase cycle; RAC3 GTPase cycle; VEGFA-VEGFR2 Pathway"	"9"	"0"	"67.0"	"45.7"	"68.4"	"66.6"	"66.4"	"72.5"	"308.2"	"337.5"	"270.6"	"424.1"	"527.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P47914"	"60S ribosomal protein L29 OS=Homo sapiens OX=9606 GN=RPL29 PE=1 SV=2"	"9"	"1"	"2"	"1"	"159"	"17.7"	"11.66"	"483.69"	"3.65"	"1"	"1"	"protein metabolism;other metabolic processes;developmental processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01779"	"6159"	"ENSG00000162244"	"RPL29"	"A8K0H3; B2R4M8; hsa:6159; P47914; Q6IPY3"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"58.2"	"38.5"	"39.7"	"44.0"	"52.9"	"46.3"	"188.4"	"177.9"	"139.8"	"194.4"	"208.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96SK2"	"Transmembrane protein 209 OS=Homo sapiens OX=9606 GN=TMEM209 PE=1 SV=2"	"4"	"1"	"1"	"1"	"561"	"62.9"	"8.63"	""	"3.63"	""	"1"	""	"other membranes"	""	"Pf09786"	"84928"	"ENSG00000146842"	"TMEM209"	"A4D1L1; hsa:84928; Q49A50; Q6PF00; Q8NCH3; Q96SK2; Q96SL6"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y314"	"Nitric oxide synthase-interacting protein OS=Homo sapiens OX=9606 GN=NOSIP PE=1 SV=1"	"5"	"1"	"2"	"1"	"301"	"33.2"	"8.82"	"341.14"	"3.63"	"1"	"1"	"other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf15906"	"51070"	"ENSG00000142546"	"NOSIP"	"hsa:51070; Q96FD2; Q9Y314"	""	"NOSIP mediated eNOS trafficking"	"1"	"0"	"52.9"	"29.8"	"37.7"	"52.5"	"54.0"	"44.9"	"159.5"	"148.5"	"126.4"	"180.1"	"224.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5Q8"	"General transcription factor 3C polypeptide 5 OS=Homo sapiens OX=9606 GN=GTF3C5 PE=1 SV=2"	"4"	"1"	"2"	"1"	"519"	"59.5"	"6.90"	"417.55"	"3.62"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09734, Pf17682"	"9328"	"ENSG00000148308"	"GTF3C5"	"A6NI44; A6NJB9; hsa:9328; Q5T7U2; Q5T7U3; Q8N2U7; Q8N857; Q96GD9; Q9H4P2; Q9Y5Q8"	""	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter"	"3"	"0"	"12.2"	"9.1"	"13.9"	"14.9"	"13.8"	"15.6"	"27.9"	"20.9"	"18.2"	"39.0"	"49.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UHR4"	"Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 OS=Homo sapiens OX=9606 GN=BAIAP2L1 PE=1 SV=2"	"4"	"1"	"1"	"1"	"511"	"56.8"	"8.68"	""	"3.60"	""	"1"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"cytoskeletal activity;other molecular function"	"Pf08397, Pf14604"	"55971"	"ENSG00000006453"	"BAIAP2L1"	"A4D268; hsa:55971; Q75L21; Q75L22; Q96CV4; Q9H5F5; Q9UHR4; Q9Y2M8"	""	"RHOF GTPase cycle; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle"	"4"	"0"	"17.4"	"11.8"	"17.5"	"14.2"	"18.1"	"16.8"	"37.3"	"31.2"	"29.9"	"49.3"	"64.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N5N7"	"39S ribosomal protein L50, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL50 PE=1 SV=2"	"13"	"1"	"2"	"1"	"158"	"18.3"	"7.88"	"356.29"	"3.59"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;cytosol;mitochondrion;translational apparatus"	""	"Pf10501"	"54534"	"ENSG00000136897"	"MRPL50"	"B7Z358; hsa:54534; Q5T7E0; Q8N5N7; Q9NX15"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BXC9"	"Bardet-Biedl syndrome 2 protein OS=Homo sapiens OX=9606 GN=BBS2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"721"	"79.8"	"6.15"	"469.77"	"3.59"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"8.6"	"7.5"	"9.9"	"10.8"	"11.2"	"11.9"	"25.2"	"36.8"	"44.4"	"68.9"	"91.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9GZT9"	"Egl nine homolog 1 OS=Homo sapiens OX=9606 GN=EGLN1 PE=1 SV=1"	"3"	"1"	"2"	"1"	"426"	"46.0"	"8.53"	"421.42"	"3.58"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01753, Pf13640"	"54583"	"ENSG00000135766"	"EGLN1"	"hsa:54583; Q8N3M8; Q9BZS8; Q9BZT0; Q9GZT9"	"Photodynamic therapy-induced HIF-1 survival signaling; Type 2 papillary renal cell carcinoma; Markers of kidney cell lineage"	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"	"4"	"0"	"24.2"	"18.8"	"24.2"	"21.6"	"24.0"	"23.3"	"64.0"	"62.7"	"44.9"	"68.6"	"94.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N3C0"	"Activating signal cointegrator 1 complex subunit 3 OS=Homo sapiens OX=9606 GN=ASCC3 PE=1 SV=3"	"1"	"1"	"2"	"1"	"2202"	"251.3"	"7.09"	"345.15"	"3.58"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271, Pf02889"	"10973"	"ENSG00000112249"	"ASCC3"	"E7EW23; hsa:10973; O43738; Q4G1A0; Q5VTN2; Q8N3C0; Q9H1I9; Q9H5A2; Q9NTR0"	"Mesodermal commitment pathway; VEGFA-VEGFR2 signaling"	"ALKBH3 mediated reversal of alkylation damage"	"3"	"0"	"13.3"	"6.1"	"25.9"	"16.0"	"18.7"	"15.4"	"22.1"	"27.2"	"17.8"	"32.9"	"39.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12959"	"Disks large homolog 1 OS=Homo sapiens OX=9606 GN=DLG1 PE=1 SV=2"	"1"	"1"	"1"	"1"	"904"	"100.4"	"5.76"	""	"3.57"	""	"1"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"extracellular matrix;plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00018, Pf00595, Pf00625, Pf09058, Pf10600, Pf10608"	"1739"	"ENSG00000075711"	"DLG1"	"A5YKK7; B4DGU1; B4DGZ8; B7ZMM0; B9EIQ5; D3DXB8; D3DXB9; E7EWL7; E9PG21; hsa:1739; Q12958; Q12959"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; Disruption of postsynaptic signaling by CNV; 3q29 copy number variation syndrome"	"Assembly and cell surface presentation of NMDA receptors; RAF/MAP kinase cascade; Ras activation upon Ca2+ influx through NMDA receptor; Unblocking of NMDA receptors, glutamate binding and activation; Synaptic adhesion-like molecules; Negative regulation of NMDA receptor-mediated neuronal transmission; Long-term potentiation; Trafficking of AMPA receptors; NrCAM interactions; Activation of Ca-permeable Kainate Receptor"	"14"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P34947"	"G protein-coupled receptor kinase 5 OS=Homo sapiens OX=9606 GN=GRK5 PE=1 SV=1"	"2"	"1"	"2"	"1"	"590"	"67.7"	"8.10"	"299.45"	"3.57"	"1"	"1"	"cell-cell signaling;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00615"	"2869"	"ENSG00000198873"	"GRK5"	"D3DRD0; hsa:2869; P34947; Q5T059"	"Myometrial relaxation and contraction pathways; Chemokine signaling pathway; Comprehensive IL-17A signaling; Calcium regulation in cardiac cells"	"G alpha (q) signalling events; G alpha (s) signalling events"	"6"	"0"	"12.8"	"5.8"	"14.2"	"14.2"	"11.2"	"14.8"	"45.6"	"55.1"	"53.1"	"117.1"	"154.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04792"	"Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2"	"8"	"1"	"1"	"1"	"205"	"22.8"	"6.40"	""	"3.56"	""	"1"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00011"	"3315"	"ENSG00000106211"	"HSPB1"	"B2R4N8; hsa:3315; P04792; Q6FI47; Q96C20; Q96EI7; Q9UC31; Q9UC34; Q9UC35; Q9UC36"	"Apoptosis-related network due to altered Notch3 in ovarian cancer; Fas ligand pathway and stress induction of heat shock proteins; MAPK signaling pathway; ATM signaling in development and disease ; VEGFA-VEGFR2 signaling; p38 MAPK signaling pathway; Extracellular vesicles in the crosstalk of cardiac cells; Ferroptosis; IL-18 signaling pathway; Intracellular trafficking proteins involved in CMT neuropathy; GDNF signaling; A network map of Macrophage-stimulating protein (MSP) signaling"	"AUF1 (hnRNP D0) binds and destabilizes mRNA; MAPK6/MAPK4 signaling; Extra-nuclear estrogen signaling; VEGFA-VEGFR2 Pathway"	"16"	"0"	"11.2"	"7.4"	"8.8"	"7.8"	"4.5"	"9.8"	"14.6"	"11.2"	"21.3"	"10.9"	"399.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49674"	"Casein kinase I isoform epsilon OS=Homo sapiens OX=9606 GN=CSNK1E PE=1 SV=1"	"6"	"2"	"4"	"2"	"416"	"47.3"	"9.66"	"1283.02"	"3.56"	"2"	"1"	"cell-cell signaling;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"102800317; 1454"	"ENSG00000213923"	"CSNK1E"	"hsa:102800317; hsa:1454; P49674"	"Alzheimer's disease and miRNA effects; Melatonin metabolism and effects; Wnt signaling pathway; Wnt signaling pathway and pluripotency; Hedgehog signaling pathway; lncRNA in canonical Wnt signaling and colorectal cancer; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Pleural mesothelioma; Alzheimer's disease"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Circadian Clock; Major pathway of rRNA processing in the nucleolus and cytosol; WNT mediated activation of DVL"	"20"	"0"	"20.1"	"14.0"	"30.6"	"19.0"	"21.1"	"28.3"	"58.5"	"51.2"	"42.4"	"71.2"	"87.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63173"	"60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2"	"23"	"2"	"3"	"1"	"70"	"8.2"	"10.10"	"688.71"	"3.56"	"2"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01781"	"6169"	"ENSG00000172809"	"RPL38"	"B2R5A8; hsa:6169; P23411; P63173"	"Mesodermal commitment pathway; Mesodermal commitment pathway; Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"16"	"0"	"68.9"	"41.2"	"59.4"	"66.6"	"63.2"	"58.7"	"259.7"	"245.2"	"173.9"	"370.3"	"419.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31025"	"Lipocalin-1 OS=Homo sapiens OX=9606 GN=LCN1 PE=1 SV=1"	"6"	"1"	"2"	"1"	"176"	"19.2"	"5.58"	"363.12"	"3.55"	"1"	"1"	"protein metabolism;other biological processes"	"non-structural extracellular"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00061"	"3933"	"ENSG00000160349"	"LCN1"	"hsa:3933; P31025; Q5T8A1"	""	"Transport of fatty acids"	"1"	"0"	"53.6"	"38.1"	"44.2"	"42.9"	"45.7"	"53.2"	"104.1"	"114.7"	"78.3"	"105.9"	"116.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43670"	"BUB3-interacting and GLEBS motif-containing protein ZNF207 OS=Homo sapiens OX=9606 GN=ZNF207 PE=1 SV=1"	"3"	"1"	"2"	"1"	"478"	"50.7"	"9.10"	"483.75"	"3.53"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	""	"7756"	"ENSG00000010244"	"ZNF207"	"A8K6Y6; E1P660; E1P661; E1P662; hsa:7756; O43670; Q53XS9; Q96HW5; Q9BUQ7"	""	""	"0"	"0"	"45.7"	"31.4"	"45.7"	"34.1"	"47.2"	"44.4"	"99.8"	"105.3"	"79.7"	"107.1"	"147.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30085"	"UMP-CMP kinase OS=Homo sapiens OX=9606 GN=CMPK1 PE=1 SV=3"	"6"	"1"	"2"	"1"	"196"	"22.2"	"5.57"	"304.59"	"3.52"	"1"	"1"	"other metabolic processes"	"cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00406"	"51727"	"ENSG00000162368"	"CMPK1"	"B2R6S5; B4DPU7; E9PGI8; hsa:51727; P30085; Q53GB7; Q5SVZ0; Q96C07; Q9UBQ8; Q9UIA2"	"Pyrimidine metabolism"	"Interconversion of nucleotide di- and triphosphates"	"2"	"0"	"9.7"	"9.0"	"11.9"	"8.6"	"15.0"	"13.8"	"17.7"	"22.6"	"18.4"	"26.7"	"35.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NY61"	"Protein AATF OS=Homo sapiens OX=9606 GN=AATF PE=1 SV=1"	"3"	"1"	"2"	"1"	"560"	"63.1"	"4.94"	"362.77"	"3.52"	"1"	"1"	"cell adhesion;stress response;developmental processes;other biological processes"	"ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf08164, Pf13339"	"26574"	"ENSG00000275700; ENSG00000276072"	"AATF"	"A6NCJ6; B3KQ26; hsa:26574; Q9NY61; Q9P0A4; Q9UNX5"	"17q12 copy number variation syndrome"	"NRAGE signals death through JNK"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96GA3"	"Protein LTV1 homolog OS=Homo sapiens OX=9606 GN=LTV1 PE=1 SV=1"	"3"	"1"	"2"	"1"	"475"	"54.8"	"4.91"	"398.45"	"3.51"	"1"	"1"	"transport;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf04180"	"84946"	"ENSG00000135521"	"LTV1"	"hsa:84946; Q96GA3; Q96JX8"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"25.9"	"28.0"	"33.1"	"44.6"	"27.5"	"46.2"	"80.6"	"58.4"	"40.9"	"62.5"	"71.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96IZ7"	"Serine/Arginine-related protein 53 OS=Homo sapiens OX=9606 GN=RSRC1 PE=1 SV=1"	"5"	"1"	"2"	"1"	"334"	"38.7"	"11.08"	"343.62"	"3.50"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	""	""	"51319"	"ENSG00000174891"	"RSRC1"	"A8K2R9; hsa:51319; Q96IZ7; Q96QK2; Q9NZE5"	""	""	"0"	"0"	"7.2"	"8.0"	"7.5"	"5.6"	"5.7"	"8.6"	"18.3"	"19.1"	"11.6"	"25.1"	"28.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQ15"	"SOSS complex subunit B1 OS=Homo sapiens OX=9606 GN=NABP2 PE=1 SV=1"	"6"	"1"	"2"	"1"	"211"	"22.3"	"9.06"	"497.29"	"3.50"	"1"	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01336"	"79035"	"ENSG00000139579"	"NABP2"	"A6NDF8; hsa:79035; Q6XYC8; Q9BQ15"	"Mesodermal commitment pathway"	"RNA polymerase II transcribes snRNA genes"	"2"	"0"	"15.9"	"10.6"	"20.3"	"26.3"	"18.8"	"20.2"	"34.0"	"29.4"	"20.2"	"26.6"	"44.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12931"	"Proto-oncogene tyrosine-protein kinase Src OS=Homo sapiens OX=9606 GN=SRC PE=1 SV=3"	"5"	"2"	"3"	"1"	"536"	"59.8"	"7.42"	"855.02"	"3.49"	"2"	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;kinase activity;other molecular function"	"Pf00017, Pf00018, Pf07714"	"6714"	"ENSG00000197122"	"SRC"	"E1P5V4; hsa:6714; P12931; Q76P87; Q86VB9; Q9H5A8"	"Androgen receptor signaling pathway; Angiogenesis; Integrin-mediated cell adhesion; RANKL/RANK signaling pathway; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Follicle stimulating hormone (FSH) signaling pathway; Prolactin signaling pathway; Microtubule cytoskeleton regulation; Thymic stromal lymphopoietin (TSLP) signaling pathway; Glioblastoma signaling pathways; AGE/RAGE pathway; Interleukin-11 signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Alpha 6 beta 4 signaling pathway; Aryl hydrocarbon receptor pathway; Bladder cancer; IL-3 signaling pathway; Aryl hydrocarbon receptor pathway; Pregnane X receptor pathway; Nuclear receptors meta-pathway; Kit receptor signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; RAC1/PAK1/p38/MMP2 pathway; Amplification and expansion of oncogenic pathways as metastatic traits; Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Robo4 and VEGF signaling pathways crosstalk; Fibrin complement receptor 3 signaling pathway; Acute viral myocarditis; NRF2-ARE regulation; EGF/EGFR signaling pathway; Relationship between inflammation, COX-2 and EGFR; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Fragile X syndrome; Gastrin signaling pathway; Hepatitis B infection; Thyroid hormones production and peripheral downstream signaling effects; Netrin-UNC5B signaling pathway; EGFR tyrosine kinase inhibitor resistance; Pleural mesothelioma; CCL18 signaling pathway; GDNF signaling; TROP2 regulatory signaling; A network map of Macrophage-stimulating protein (MSP) signaling; 5q35 copy number variation; EPO receptor signaling; Notch signaling pathway; ErbB signaling pathway"	"Regulation of RUNX3 expression and activity; G alpha (i) signalling events; Extra-nuclear estrogen signaling; GPER1 signaling; PIP3 activates AKT signaling; Signaling by BRAF and RAF1 fusions; RHOU GTPase cycle; Constitutive Signaling by Aberrant PI3K in Cancer; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; DCC mediated attractive signaling; Downstream signal transduction; Signaling by ERBB2; Nuclear signaling by ERBB4; RAF activation; GAB1 signalosome; MET activates PTK2 signaling; Signaling by CSF1 (M-CSF) in myeloid cells; RUNX2 regulates osteoblast differentiation; Long-term potentiation; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; InlA-mediated entry of Listeria monocytogenes into host cells; Regulation of commissural axon pathfinding by SLIT and ROBO; Netrin mediated repulsion signals; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; GRB2:SOS provides linkage to MAPK signaling for Integrins ; p130Cas linkage to MAPK signaling for integrins; Activated NTRK2 signals through FYN; Downregulation of ERBB4 signaling; Regulation of RUNX1 Expression and Activity; Activated NTRK3 signals through PI3K"	"87"	"0"	"40.9"	"27.1"	"37.5"	"33.9"	"30.3"	"39.7"	"59.7"	"57.7"	"42.3"	"63.4"	"77.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00390"	"Glutathione reductase, mitochondrial OS=Homo sapiens OX=9606 GN=GSR PE=1 SV=2"	"2"	"1"	"2"	"1"	"522"	"56.2"	"8.50"	"275.20"	"3.49"	"1"	"1"	"other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion"	"other molecular function"	"Pf00070, Pf02852"	"2936"	"ENSG00000104687"	"GSR"	"C8KIL8; C8KIL9; C8KIM0; D3DSV3; hsa:2936; P00390; Q7Z5C9; Q9NP63"	"Glutathione metabolism; Selenium micronutrient network; Trans-sulfuration, one-carbon metabolism and related pathways; Nuclear receptors meta-pathway; NRF2 pathway; Amino acid metabolism; Oxidative stress response; Vitamin D-sensitive calcium signaling in depression; Sulfation biotransformation reaction; Metapathway biotransformation Phase I and II"	""	"10"	"0"	"21.3"	"15.8"	"32.3"	"22.6"	"23.1"	"18.7"	"22.6"	"22.8"	"16.3"	"30.9"	"52.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HAV0"	"Guanine nucleotide-binding protein subunit beta-4 OS=Homo sapiens OX=9606 GN=GNB4 PE=1 SV=3"	"5"	"1"	"2"	"1"	"340"	"37.5"	"6.00"	"349.43"	"3.47"	"1"	"1"	"signal transduction"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00400"	"59345"	"ENSG00000114450"	"GNB4"	"B3KMH5; D3DNR8; hsa:59345; Q9HAV0"	"Myometrial relaxation and contraction pathways; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Ras signaling; Calcium regulation in cardiac cells"	"G alpha (i) signalling events; G alpha (z) signalling events; ADP signalling through P2Y purinoceptor 12; Extra-nuclear estrogen signaling; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; G alpha (12/13) signalling events; G alpha (q) signalling events; Thrombin signalling through proteinase activated receptors (PARs); Activation of G protein gated Potassium channels; G-protein activation; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; G beta:gamma signalling through PI3Kgamma; Prostacyclin signalling through prostacyclin receptor; Adrenaline,noradrenaline inhibits insulin secretion; Ca2+ pathway; G beta:gamma signalling through PLC beta; ADP signalling through P2Y purinoceptor 1; Glucagon-type ligand receptors; Thromboxane signalling through TP receptor; Vasopressin regulates renal water homeostasis via Aquaporins; Presynaptic function of Kainate receptors; G beta:gamma signalling through BTK; G beta:gamma signalling through CDC42; Inhibition  of voltage gated Ca2+ channels via Gbeta/gamma subunits; Glucagon signaling in metabolic regulation"	"34"	"0"	"22.5"	"15.6"	"21.2"	"22.2"	"19.3"	"21.4"	"41.4"	"48.0"	"39.4"	"57.2"	"116.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14669"	"E3 ubiquitin-protein ligase TRIP12 OS=Homo sapiens OX=9606 GN=TRIP12 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1992"	"220.3"	"8.48"	"342.25"	"3.46"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00632"	"9320"	"ENSG00000153827"	"TRIP12"	"D4HL82; hsa:9320; Q14669; Q14CA3; Q14CF1; Q15644; Q53R87; Q53TE7"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	"12.6"	"9.2"	"14.8"	"14.7"	"16.0"	"16.7"	"28.3"	"25.6"	"19.3"	"39.0"	"53.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82932"	"28S ribosomal protein S6, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS6 PE=1 SV=3"	"10"	"1"	"2"	"1"	"125"	"14.2"	"9.26"	"396.20"	"3.45"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf01250"	"64968"	"ENSG00000243927"	"MRPS6"	"B2R573; hsa:64968; P82932; Q96Q64; Q9BSK8; Q9BW89"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"44.9"	"25.4"	"55.1"	"27.6"	"38.1"	"53.4"	"70.4"	"59.4"	"51.1"	"76.8"	"117.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NCW5"	"NAD(P)H-hydrate epimerase OS=Homo sapiens OX=9606 GN=NAXE PE=1 SV=2"	"6"	"1"	"2"	"1"	"288"	"31.7"	"7.66"	"255.77"	"3.45"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"non-structural extracellular;mitochondrion;other cell component"	"other molecular function"	"Pf03853"	"128240"	"ENSG00000163382"	"NAXE"	"B4DGY3; hsa:128240; Q496C6; Q5T3I2; Q8NCW5"	""	"Nicotinamide salvaging"	"1"	"0"	"17.7"	"11.3"	"17.3"	"15.0"	"15.3"	"21.1"	"28.2"	"29.4"	"21.5"	"37.5"	"39.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6M4"	"Casein kinase I isoform gamma-3 OS=Homo sapiens OX=9606 GN=CSNK1G3 PE=1 SV=2"	"3"	"1"	"2"	"1"	"447"	"51.4"	"9.22"	"308.84"	"3.45"	"1"	"1"	"cell-cell signaling;protein metabolism;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf12605"	"1456"	"ENSG00000151292"	"CSNK1G3"	"A8K040; B4DSH2; B7Z9Q4; E7EVD0; hsa:1456; Q86WZ7; Q9Y6M3; Q9Y6M4"	"Hedgehog signaling pathway"	""	"1"	"0"	"9.1"	"5.7"	"9.5"	"13.8"	"9.1"	"7.0"	"22.9"	"21.3"	"16.1"	"32.3"	"44.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07948"	"Tyrosine-protein kinase Lyn OS=Homo sapiens OX=9606 GN=LYN PE=1 SV=3"	"2"	"1"	"2"	"1"	"512"	"58.5"	"7.11"	"296.44"	"3.44"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;kinase activity;other molecular function"	"Pf00017, Pf00018, Pf07714"	"4067"	"ENSG00000254087"	"LYN"	"A0AVQ5; hsa:4067; P07948"	"IL-5 signaling pathway; RANKL/RANK signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; B cell receptor signaling pathway; IL-3 signaling pathway; Kit receptor signaling pathway; Chemokine signaling pathway; Microglia pathogen phagocytosis pathway; GDNF signaling"	"FCGR activation; FCGR3A-mediated IL10 synthesis; FCGR3A-mediated phagocytosis; Regulation of signaling by CBL; EPHB-mediated forward signaling; Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants; Regulation of KIT signaling; EPH-ephrin mediated repulsion of cells; EPHA-mediated growth cone collapse; Signaling by CSF1 (M-CSF) in myeloid cells; CD28 co-stimulation; PECAM1 interactions; CTLA4 inhibitory signaling; Role of LAT2/NTAL/LAB on calcium mobilization; FCERI mediated MAPK activation; FCERI mediated Ca+2 mobilization; FCERI mediated NF-kB activation; CD22 mediated BCR regulation; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Erythropoietin activates Phosphoinositide-3-kinase (PI3K); GPVI-mediated activation cascade; Cyclin D associated events in G1; Growth hormone receptor signaling; Inactivation of CSF3 (G-CSF) signaling; Erythropoietin activates Phospholipase C gamma (PLCG); Erythropoietin activates STAT5; Erythropoietin activates RAS; Platelet Adhesion to exposed collagen; CD209 (DC-SIGN) signaling; Dectin-2 family"	"45"	"0"	"45.4"	"32.5"	"46.7"	"36.7"	"46.6"	"44.1"	"76.2"	"66.8"	"39.0"	"96.5"	"122.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53999"	"Activated RNA polymerase II transcriptional coactivator p15 OS=Homo sapiens OX=9606 GN=SUB1 PE=1 SV=3"	"10"	"1"	"2"	"1"	"127"	"14.4"	"9.60"	"368.08"	"3.44"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02229"	"10923"	"ENSG00000113387"	"SUB1"	"hsa:10923; P53999; Q96L29"	""	""	"0"	"0"	"13.0"	"12.6"	"13.2"	"20.2"	"12.7"	"17.2"	"97.6"	"80.2"	"55.0"	"78.7"	"84.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q2TAA2"	"Isoamyl acetate-hydrolyzing esterase 1 homolog OS=Homo sapiens OX=9606 GN=IAH1 PE=1 SV=1"	"15"	"2"	"2"	"2"	"248"	"27.6"	"5.30"	"284.78"	"3.40"	"1"	"1"	"other metabolic processes"	""	"other molecular function"	"Pf13472"	"285148"	"ENSG00000134330"	"IAH1"	"B4DMV3; hsa:285148; Q2TAA2"	""	""	"0"	"0"	"12.3"	"13.8"	"23.4"	"20.4"	"25.7"	"14.2"	"28.3"	"32.3"	"24.1"	"35.9"	"39.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96B26"	"Exosome complex component RRP43 OS=Homo sapiens OX=9606 GN=EXOSC8 PE=1 SV=1"	"6"	"1"	"2"	"1"	"276"	"30.0"	"5.30"	"261.22"	"3.39"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01138, Pf03725"	"11340"	"ENSG00000120699"	"EXOSC8"	"hsa:11340; O43480; Q5TBA5; Q96B26"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	"6"	"0"	"18.6"	"15.0"	"20.6"	"15.6"	"14.9"	"28.0"	"35.8"	"39.0"	"33.7"	"49.7"	"55.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63098"	"Calcineurin subunit B type 1 OS=Homo sapiens OX=9606 GN=PPP3R1 PE=1 SV=2"	"7"	"1"	"2"	"1"	"170"	"19.3"	"4.81"	"306.33"	"3.38"	"1"	"1"	"protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf13499"	"5534"	"ENSG00000221823"	"PPP3R1"	"B2RC10; B5MDU4; hsa:5534; P06705; P15117; P63098; Q08044; Q53SL0"	"Energy metabolism; Transcription factors regulate miRNAs related to cardiac hypertrophy; Alzheimer's disease and miRNA effects; Initiation of transcription and translation elongation at the HIV-1 LTR; MAPK signaling pathway; Wnt signaling; Vitamin D in inflammatory diseases; Regucalcin in proximal tubule epithelial kidney cells; Alzheimer's disease"	"FCERI mediated Ca+2 mobilization; Ca2+ pathway; CLEC7A (Dectin-1) induces NFAT activation; Calcineurin activates NFAT; DARPP-32 events; Activation of BAD and translocation to mitochondria"	"15"	"0"	"18.3"	"13.2"	"19.9"	"14.0"	"15.5"	"23.7"	"29.5"	"23.0"	"20.7"	"29.2"	"51.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBC2"	"Epidermal growth factor receptor substrate 15-like 1 OS=Homo sapiens OX=9606 GN=EPS15L1 PE=1 SV=1"	"3"	"1"	"1"	"1"	"864"	"94.2"	"5.11"	""	"3.36"	""	"1"	"transport"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf12763"	"58513"	"ENSG00000127527"	"EPS15L1"	"A2RRF3; A5PL29; B4DKA3; hsa:58513; Q9UBC2"	"EGF/EGFR signaling pathway"	"Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation"	"4"	"0"	"4.8"	"4.2"	"5.0"	"10.7"	"8.2"	"8.7"	"19.0"	"18.9"	"12.3"	"24.7"	"28.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P2N5"	"RNA-binding protein 27 OS=Homo sapiens OX=9606 GN=RBM27 PE=1 SV=2"	"2"	"2"	"3"	"1"	"1060"	"118.6"	"9.19"	"794.50"	"3.33"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf00076, Pf00642, Pf01480"	"54439"	"ENSG00000091009"	"RBM27"	"hsa:54439; Q8IYW9; Q9P2N5"	""	""	"0"	"0"	"29.4"	"17.0"	"22.1"	"18.7"	"28.8"	"25.6"	"57.6"	"65.9"	"55.2"	"74.9"	"118.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P37198"	"Nuclear pore glycoprotein p62 OS=Homo sapiens OX=9606 GN=NUP62 PE=1 SV=3"	"3"	"1"	"2"	"1"	"522"	"53.2"	"5.31"	"309.31"	"3.32"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"other membranes;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf05064"	"23636"	"ENSG00000213024"	"NUP62"	"B3KWU5; hsa:23636; P37198; Q503A4; Q6GTM2; Q96C43; Q9NSL1"	"7q11.23 copy number variation syndrome"	"Regulation of HSF1-mediated heat shock response; Nuclear Pore Complex (NPC) Disassembly; HCMV Early Events; Transport of Mature mRNA derived from an Intron-Containing Transcript; HCMV Late Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Postmitotic nuclear pore complex (NPC) reformation"	"30"	"0"	"18.0"	"13.8"	"18.2"	"13.6"	"16.0"	"22.0"	"38.5"	"32.7"	"27.5"	"37.0"	"57.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRW3"	"DNA dC->dU-editing enzyme APOBEC-3C OS=Homo sapiens OX=9606 GN=APOBEC3C PE=1 SV=2"	"12"	"2"	"2"	"2"	"190"	"22.8"	"7.59"	"235.93"	"3.32"	"1"	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf18782"	"27350"	"ENSG00000244509"	"APOBEC3C"	"B2R884; hsa:27350; Q5JZ92; Q7Z2N7; Q96F12; Q9NRW3"	""	"Formation of the Editosome"	"2"	"0"	"40.5"	"24.0"	"44.6"	"24.1"	"46.3"	"30.3"	"88.5"	"83.0"	"51.7"	"78.3"	"94.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92734"	"Protein TFG OS=Homo sapiens OX=9606 GN=TFG PE=1 SV=2"	"4"	"1"	"2"	"1"	"400"	"43.4"	"5.10"	"444.56"	"3.31"	"1"	"1"	"cell organization and biogenesis;transport"	"cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00564"	"10342"	"ENSG00000114354"	"TFG"	"D3DN49; G5E9V1; hsa:10342; K0J5S8; K0J6K2; Q15656; Q92734; Q969I2"	""	"Signaling by ALK fusions and activated point mutants; COPII-mediated vesicle transport"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q12789"	"General transcription factor 3C polypeptide 1 OS=Homo sapiens OX=9606 GN=GTF3C1 PE=1 SV=4"	"1"	"2"	"3"	"2"	"2109"	"238.7"	"7.30"	"618.19"	"3.31"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04182"	"2975"	"ENSG00000077235"	"GTF3C1"	"B2RP21; hsa:2975; Q12789; Q12838; Q6DKN9; Q9Y4W9"	""	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter"	"3"	"0"	"20.4"	"10.4"	"12.5"	"22.8"	"19.7"	"25.6"	"57.6"	"57.9"	"39.4"	"66.3"	"77.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9GZN1"	"Actin-related protein 6 OS=Homo sapiens OX=9606 GN=ACTR6 PE=1 SV=1"	"3"	"1"	"2"	"1"	"396"	"45.8"	"5.03"	"306.13"	"3.31"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00022"	"64431"	"ENSG00000075089"	"ACTR6"	"B3KW37; B4DLG9; hsa:64431; Q53GH2; Q9BY39; Q9GZN1; Q9H8H6"	""	""	"0"	"0"	"20.2"	"14.7"	"28.3"	"17.8"	"21.9"	"20.1"	"24.0"	"20.9"	"20.0"	"24.3"	"59.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKV8"	"Protein argonaute-2 OS=Homo sapiens OX=9606 GN=AGO2 PE=1 SV=3"	"2"	"1"	"2"	"1"	"859"	"97.1"	"9.19"	"403.21"	"3.30"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02170, Pf02171, Pf08699, Pf16486, Pf16487, Pf16488"	"27161"	"ENSG00000123908"	"AGO2"	"hsa:27161; Q8TCZ5; Q8WV58; Q96ID1; Q9UKV8"	"exRNA mechanism of action and biogenesis; Fragile X syndrome; Male infertility; Influence of laminopathies on Wnt signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies"	"Transcriptional regulation by small RNAs; MAPK6/MAPK4 signaling; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; TP53 Regulates Metabolic Genes; Pre-NOTCH Transcription and Translation; Ca2+ pathway; Regulation of MECP2 expression and activity; NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux; Small interfering RNA (siRNA) biogenesis; Regulation of RUNX1 Expression and Activity; Regulation of CDH11 mRNA translation by microRNAs; Regulation of NPAS4 mRNA translation; Post-transcriptional silencing by small RNAs; Competing endogenous RNAs (ceRNAs) regulate PTEN translation"	"22"	"0"	"19.2"	"13.9"	"16.8"	"16.3"	"22.7"	"20.8"	"58.1"	"64.6"	"45.4"	"87.4"	"96.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43181"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS4 PE=1 SV=1"	"5"	"1"	"2"	"1"	"175"	"20.1"	"10.30"	"399.51"	"3.29"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;mitochondrion"	"transporter activity"	"Pf04800"	"4724"	"ENSG00000164258"	"NDUFS4"	"hsa:4724; O43181; Q9BS69"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"171.8"	"88.3"	"118.5"	"110.8"	"127.7"	"136.1"	"278.0"	"243.1"	"172.5"	"343.4"	"540.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13200"	"26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3"	"1"	"1"	"2"	"1"	"908"	"100.1"	"5.20"	"356.97"	"3.29"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf01851, Pf17781, Pf18051"	"5708"	"ENSG00000175166"	"PSMD2"	"B4DX07; B4DXY1; E7EW34; E9PCS3; hsa:5708; Q12932; Q13200; Q15321; Q53XQ4; Q96I12"	"Proteasome degradation; Alzheimer's disease and miRNA effects; TNF-alpha signaling pathway; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"ER-Phagosome pathway; Neutrophil degranulation; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"65"	"0"	"128.3"	"67.5"	"114.5"	"94.7"	"105.8"	"119.1"	"173.2"	"170.8"	"134.6"	"213.5"	"237.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13137"	"Calcium-binding and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=CALCOCO2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"446"	"52.2"	"5.02"	"272.95"	"3.27"	"1"	"1"	"other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf17751"	"10241"	"ENSG00000136436"	"CALCOCO2"	"B2RBT0; B4DDC4; B4DDT4; B4DP36; B4E0C0; E7ENK0; E7ETP5; E9PBE5; hsa:10241; Q13137; Q53FQ5; Q53HB5; Q6IBN9; Q9BTF7"	""	""	"0"	"0"	"22.5"	"12.4"	"21.4"	"21.6"	"26.7"	"21.8"	"43.3"	"41.6"	"27.6"	"51.1"	"56.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6PJT7"	"Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1"	"1"	"1"	"2"	"1"	"736"	"82.8"	"7.31"	"282.13"	"3.27"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf14608"	"79882"	"ENSG00000100722"	"ZC3H14"	"A8MY46; B4DXU8; B4DZW7; B4E2H4; G3V5R4; hsa:79882; Q6MZU4; Q6PJ32; Q6PJT7; Q6PUI6; Q6PUI8; Q86TQ5; Q86TW0; Q86TW1; Q8NCT6; Q8NCZ3; Q8TDE2; Q9HAC9; Q9Y5A0"	""	""	"0"	"0"	"10.4"	"3.3"	"11.5"	"8.0"	"10.8"	"15.3"	"17.8"	"14.2"	"13.4"	"22.3"	"36.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13685"	"Angio-associated migratory cell protein OS=Homo sapiens OX=9606 GN=AAMP PE=1 SV=2"	"3"	"1"	"1"	"1"	"434"	"46.7"	"4.42"	""	"3.26"	""	"1"	"developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00400"	"14"	"ENSG00000127837"	"AAMP"	"hsa:14; Q13685; Q8WUJ9; Q96H92"	"Nucleotide-binding oligomerization domain (NOD) pathway"	"NOD1/2 Signaling Pathway; Thromboxane signalling through TP receptor; Signaling by EGFR; Signaling by VEGF"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16527"	"Cysteine and glycine-rich protein 2 OS=Homo sapiens OX=9606 GN=CSRP2 PE=1 SV=3"	"7"	"1"	"2"	"1"	"193"	"20.9"	"8.62"	"336.59"	"3.26"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412"	"1466"	"ENSG00000175183"	"CSRP2"	"hsa:1466; Q16527; Q93030"	"Mesodermal commitment pathway; VEGFA-VEGFR2 signaling; H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity"	""	"3"	"0"	"16.6"	"19.8"	"18.3"	"17.9"	"17.4"	"19.0"	"50.0"	"50.7"	"39.5"	"56.8"	"67.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HDC5"	"Junctophilin-1 OS=Homo sapiens OX=9606 GN=JPH1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"661"	"71.6"	"9.32"	"319.25"	"3.24"	"1"	"1"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus"	"other molecular function"	"Pf02493"	"56704"	"ENSG00000104369"	"JPH1"	"B2RTZ0; hsa:56704; Q9HDC5"	""	""	"0"	"0"	"6.6"	"4.4"	"7.1"	"4.1"	"8.0"	"6.6"	"14.0"	"16.2"	"11.5"	"25.4"	"35.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z4G4"	"tRNA (guanine(10)-N2)-methyltransferase homolog OS=Homo sapiens OX=9606 GN=TRMT11 PE=1 SV=1"	"3"	"1"	"2"	"1"	"463"	"53.4"	"7.78"	"406.89"	"3.24"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01170"	"60487"	"ENSG00000066651"	"TRMT11"	"E1P570; hsa:60487; Q5JY11; Q6PGQ5; Q7Z4G4; Q9HC13"	""	"tRNA modification in the nucleus and cytosol"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96MG7"	"Non-structural maintenance of chromosomes element 3 homolog OS=Homo sapiens OX=9606 GN=NSMCE3 PE=1 SV=1"	"6"	"2"	"3"	"2"	"304"	"34.3"	"9.28"	"616.50"	"3.24"	"2"	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf01454"	"56160"	"ENSG00000185115; ENSG00000282130"	"NSMCE3"	"hsa:56160; Q8IW16; Q8TEI6; Q96MG7; Q9H214"	"15q11q13 copy number variation"	"SUMOylation of DNA damage response and repair proteins"	"2"	"0"	"44.8"	"31.0"	"33.7"	"32.2"	"59.0"	"42.1"	"125.0"	"125.6"	"103.3"	"161.5"	"190.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9ULX6"	"A-kinase anchor protein 8-like OS=Homo sapiens OX=9606 GN=AKAP8L PE=1 SV=4"	"4"	"2"	"3"	"2"	"646"	"71.6"	"5.05"	"582.38"	"3.22"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04988"	"26993"	"ENSG00000011243"	"AKAP8L"	"B4DJ74; B5BU90; hsa:26993; O94792; Q96J58; Q9NRQ0; Q9UGM0; Q9ULX6"	""	"Formation of WDR5-containing histone-modifying complexes"	"1"	"0"	"32.4"	"24.2"	"31.9"	"32.5"	"28.0"	"43.8"	"44.7"	"46.1"	"37.9"	"64.3"	"92.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15020"	"Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1"	"1"	"1"	"2"	"1"	"963"	"109.9"	"5.57"	"271.51"	"3.21"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00076, Pf05391, Pf16605"	"9733"	"ENSG00000075856"	"SART3"	"A8K2E4; B7ZKM0; hsa:9733; Q15020; Q2M2H0; Q58F06; Q8IUS1; Q96J95"	""	""	"0"	"0"	"19.0"	"20.9"	"22.1"	"26.4"	"20.7"	"30.2"	"58.1"	"56.0"	"36.4"	"51.1"	"77.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96K21"	"Abscission/NoCut checkpoint regulator OS=Homo sapiens OX=9606 GN=ZFYVE19 PE=1 SV=3"	"3"	"1"	"2"	"1"	"471"	"51.5"	"5.73"	"349.96"	"3.21"	"1"	"1"	"cell cycle OR cell proliferation;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"other molecular function"	"Pf01363"	"84936"	"ENSG00000166140"	"ZFYVE19"	"B3KVB2; C9JNF4; H3BUF9; hsa:84936; Q86WC2; Q8WU96; Q96K21"	""	""	"0"	"0"	"50.7"	"27.7"	"34.2"	"47.2"	"34.6"	"42.3"	"97.9"	"83.7"	"63.4"	"94.3"	"102.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53985"	"Monocarboxylate transporter 1 OS=Homo sapiens OX=9606 GN=SLC16A1 PE=1 SV=3"	"2"	"1"	"2"	"1"	"500"	"53.9"	"8.66"	"361.76"	"3.20"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"transporter activity;other molecular function"	"Pf07690"	"6566"	"ENSG00000155380; ENSG00000281917"	"SLC16A1"	"hsa:6566; P53985; Q49A45; Q5T8R6; Q9NSJ9"	"Photodynamic therapy-induced HIF-1 survival signaling; Fragile X syndrome; Glucose metabolism in triple-negative breast cancer cells"	"Pyruvate metabolism; Aspirin ADME; Basigin interactions; Proton-coupled monocarboxylate transport; Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT)"	"8"	"0"	"15.2"	"10.8"	"11.1"	"5.9"	"12.9"	"9.7"	"28.8"	"25.3"	"23.2"	"27.0"	"29.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q69YN2"	"CWF19-like protein 1 OS=Homo sapiens OX=9606 GN=CWF19L1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"538"	"60.6"	"7.24"	"289.29"	"3.20"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"enzyme regulator activity"	"Pf04676, Pf04677"	"55280"	"ENSG00000095485"	"CWF19L1"	"B4DHX1; D3DR66; hsa:55280; Q5W0I3; Q69YN2; Q96HC3; Q9H865; Q9NV13"	""	""	"0"	"0"	"10.1"	"10.9"	"21.0"	"17.7"	"16.0"	"18.1"	"32.8"	"35.1"	"26.1"	"46.4"	"67.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31689"	"DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2"	"6"	"3"	"4"	"3"	"397"	"44.8"	"7.08"	"824.87"	"3.19"	"3"	"1"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00226, Pf00684, Pf01556"	"3301"	"ENSG00000086061"	"DNAJA1"	"hsa:3301; P31689; Q5T7Q0; Q86TL9"	"VEGFA-VEGFR2 signaling; Exercise-induced circadian regulation"	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand"	"3"	"0"	"326.8"	"179.2"	"251.6"	"210.5"	"247.8"	"281.9"	"497.7"	"466.4"	"367.5"	"601.0"	"980.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NQ50"	"39S ribosomal protein L40, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL40 PE=1 SV=1"	"7"	"1"	"2"	"1"	"206"	"24.5"	"9.63"	"601.47"	"3.19"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	""	"Pf09812"	"64976"	"ENSG00000185608"	"MRPL40"	"B3KVZ7; hsa:64976; O95134; Q9NQ50"	"22q11.2 copy number variation syndrome"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00170"	"AH receptor-interacting protein OS=Homo sapiens OX=9606 GN=AIP PE=1 SV=2"	"6"	"1"	"2"	"1"	"330"	"37.6"	"6.29"	"412.39"	"3.19"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"8.4"	"4.7"	"7.5"	"6.2"	"6.8"	"14.4"	"16.2"	"15.1"	"16.1"	"16.4"	"22.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99714"	"3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3"	"5"	"1"	"2"	"1"	"261"	"26.9"	"7.78"	"368.53"	"3.18"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00106"	"3028"	"ENSG00000072506"	"HSD17B10"	"hsa:3028; Q5H927; Q6IBS9; Q8TCV9; Q96HD5; Q99714"	"Alzheimer's disease and miRNA effects; Valproic acid pathway; Alzheimer's disease"	"Branched-chain amino acid catabolism; tRNA processing in the mitochondrion; tRNA modification in the mitochondrion; rRNA processing in the mitochondrion"	"7"	"0"	"27.6"	"20.0"	"31.9"	"26.7"	"28.5"	"26.1"	"47.6"	"43.3"	"39.5"	"52.0"	"83.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09211"	"Glutathione S-transferase P OS=Homo sapiens OX=9606 GN=GSTP1 PE=1 SV=2"	"5"	"1"	"2"	"1"	"210"	"23.3"	"5.64"	"255.33"	"3.17"	"1"	"1"	"cell cycle OR cell proliferation;other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;cytosol;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02798, Pf14497"	"2950"	"ENSG00000084207"	"GSTP1"	"hsa:2950; O00460; P09211; Q15690; Q5TZY3"	"Nuclear receptors meta-pathway; NRF2 pathway; Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling; Exercise-induced circadian regulation; Arachidonate epoxygenase / epoxide hydrolase; Metapathway biotransformation Phase I and II"	"Neutrophil degranulation; Paracetamol ADME; Detoxification of Reactive Oxygen Species; Glutathione conjugation"	"10"	"0"	"42.1"	"35.9"	"61.2"	"43.6"	"49.9"	"50.1"	"72.9"	"73.2"	"54.3"	"99.9"	"126.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16864"	"V-type proton ATPase subunit F OS=Homo sapiens OX=9606 GN=ATP6V1F PE=1 SV=2"	"10"	"1"	"2"	"1"	"119"	"13.4"	"5.52"	"471.18"	"3.16"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle"	"transporter activity"	"Pf01990"	"9296"	"ENSG00000128524"	"ATP6V1F"	"C9J2K4; hsa:9296; Q16864; Q6IBA8"	"Proximal tubule transport"	"Amino acids regulate mTORC1; ROS and RNS production in phagocytes; Insulin receptor recycling; Transferrin endocytosis and recycling; Ion channel transport"	"6"	"0"	"28.2"	"23.9"	"22.3"	"29.0"	"32.9"	"33.6"	"54.7"	"56.0"	"49.1"	"70.8"	"86.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51572"	"B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3"	"4"	"1"	"2"	"1"	"246"	"28.0"	"8.44"	"357.25"	"3.16"	"1"	"1"	"cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf05529, Pf18035"	"10134"	"ENSG00000185825"	"BCAP31"	"B3KQ79; D3DWV5; hsa:10134; P51572; Q13836; Q96CF0"	""	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC; RHOA GTPase cycle; Apoptotic cleavage of cellular proteins"	"4"	"0"	"87.9"	"49.8"	"63.1"	"61.6"	"89.1"	"79.7"	"147.2"	"131.1"	"90.5"	"148.1"	"230.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IWC1"	"MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2"	"2"	"1"	"2"	"1"	"876"	"98.4"	"9.32"	"529.51"	"3.15"	"1"	"1"	"cell organization and biogenesis"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf05672"	"79649"	"ENSG00000129680"	"MAP7D3"	"A2A2J0; A6NCZ7; A6NHR4; B4DWD2; H7BY77; hsa:79649; Q5JXI5; Q5JXI6; Q6P2S1; Q8IWC1; Q9H9M8"	""	""	"0"	"0"	"25.4"	"17.6"	"24.2"	"34.4"	"34.7"	"31.1"	"85.8"	"77.5"	"68.2"	"101.1"	"124.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15164"	"Transcription intermediary factor 1-alpha OS=Homo sapiens OX=9606 GN=TRIM24 PE=1 SV=3"	"2"	"1"	"2"	"1"	"1050"	"116.8"	"7.11"	"456.22"	"3.13"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;kinase activity;other molecular function"	"Pf00439, Pf00628, Pf00643"	"8805"	"ENSG00000122779"	"TRIM24"	"A4D1R7; A4D1R8; hsa:8805; O15164; O95854"	""	"Signaling by BRAF and RAF1 fusions; Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease"	"3"	"0"	"9.6"	"10.9"	"8.5"	"11.0"	"9.1"	"12.1"	"21.8"	"14.4"	"9.6"	"15.8"	"13.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62310"	"U6 snRNA-associated Sm-like protein LSm3 OS=Homo sapiens OX=9606 GN=LSM3 PE=1 SV=2"	"20"	"2"	"3"	"2"	"102"	"11.8"	"4.70"	"608.48"	"3.13"	"2"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	"27258"	"ENSG00000170860"	"LSM3"	"hsa:27258; P62310; Q6IAH0; Q9Y4Z1"	""	"mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease"	"2"	"0"	"151.8"	"95.3"	"150.3"	"127.7"	"135.3"	"128.1"	"321.4"	"277.0"	"218.5"	"360.2"	"408.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14331"	"Protein FRG1 OS=Homo sapiens OX=9606 GN=FRG1 PE=1 SV=1"	"5"	"1"	"2"	"1"	"258"	"29.2"	"9.01"	"437.28"	"3.12"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus"	"cytoskeletal activity"	"Pf06229"	"2483"	"ENSG00000109536; ENSG00000275145; ENSG00000283153; ENSG00000283630"	"FRG1"	"A8K775; hsa:2483; Q14331"	""	""	"0"	"0"	"49.6"	"27.7"	"53.5"	"35.0"	"47.0"	"37.5"	"101.6"	"113.2"	"123.2"	"221.8"	"326.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19022"	"Cadherin-2 OS=Homo sapiens OX=9606 GN=CDH2 PE=1 SV=4"	"2"	"1"	"2"	"1"	"906"	"99.7"	"4.81"	"238.44"	"3.11"	"1"	"1"	"cell adhesion;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00028, Pf01049, Pf08758"	"1000"	"ENSG00000170558"	"CDH2"	"A8MWK3; B0YIY6; hsa:1000; P19022; Q14923; Q8N173"	"Neural crest differentiation; Arrhythmogenic right ventricular cardiomyopathy; Brain-derived neurotrophic factor (BDNF) signaling pathway; Primary focal segmental glomerulosclerosis (FSGS); Splicing factor NOVA regulated synaptic proteins; Epithelial to mesenchymal transition in colorectal cancer; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; Pleural mesothelioma; CCL18 signaling pathway; GDNF signaling; A network map of Macrophage-stimulating protein (MSP) signaling"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Myogenesis; Adherens junctions interactions"	"16"	"0"	"13.2"	"12.8"	"14.4"	"20.9"	"14.6"	"21.4"	"38.8"	"39.6"	"37.5"	"59.0"	"76.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95456"	"Proteasome assembly chaperone 1 OS=Homo sapiens OX=9606 GN=PSMG1 PE=1 SV=1"	"7"	"1"	"1"	"1"	"288"	"32.8"	"7.17"	""	"3.10"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf16094"	"8624"	"ENSG00000183527"	"PSMG1"	"B5BUN2; hsa:8624; O95456; Q6FHA3; Q6FHD3; Q6S713"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30049"	"ATP synthase subunit delta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1D PE=1 SV=2"	"5"	"1"	"2"	"1"	"168"	"17.5"	"5.49"	"395.30"	"3.10"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity"	"Pf02823"	"513"	"ENSG00000099624"	"ATP5F1D"	"D6W5Y3; hsa:513; P30049; Q6FG90"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"5"	"0"	"310.6"	"125.1"	"157.0"	"224.6"	"166.1"	"250.1"	"347.2"	"334.3"	"215.7"	"395.4"	"537.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BPX5"	"Actin-related protein 2/3 complex subunit 5-like protein OS=Homo sapiens OX=9606 GN=ARPC5L PE=1 SV=1"	"8"	"1"	"2"	"1"	"153"	"16.9"	"6.60"	"431.21"	"3.10"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf04699"	"81873"	"ENSG00000136950"	"ARPC5L"	"hsa:81873; Q7Z523; Q9BPX5"	"Pathogenic Escherichia coli infection; VEGFA-VEGFR2 signaling"	""	"2"	"0"	"26.7"	"13.8"	"23.7"	"27.5"	"24.2"	"31.4"	"59.7"	"85.4"	"86.2"	"148.8"	"329.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BV20"	"Methylthioribose-1-phosphate isomerase OS=Homo sapiens OX=9606 GN=MRI1 PE=1 SV=1"	"4"	"1"	"2"	"1"	"369"	"39.1"	"6.30"	"341.25"	"3.09"	"1"	"1"	"other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01008"	"84245"	"ENSG00000037757"	"MRI1"	"hsa:84245; Q8NDC9; Q9BV20"	"Methionine de novo and salvage pathway"	"Methionine salvage pathway"	"2"	"0"	"11.1"	"3.2"	"13.3"	"9.2"	"13.1"	"9.9"	"16.3"	"12.7"	"6.3"	"16.0"	"25.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95168"	"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 OS=Homo sapiens OX=9606 GN=NDUFB4 PE=1 SV=3"	"8"	"1"	"2"	"1"	"129"	"15.2"	"9.85"	"321.88"	"3.09"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;transport"	"other membranes;mitochondrion;nucleus"	"transporter activity"	"Pf07225"	"4710"	"ENSG00000065518"	"NDUFB4"	"B2RUY3; B9EJC7; hsa:4710; O95168"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"109.4"	"84.6"	"85.3"	"68.7"	"90.0"	"94.9"	"134.3"	"145.8"	"121.3"	"232.2"	"364.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12800"	"Alpha-globin transcription factor CP2 OS=Homo sapiens OX=9606 GN=TFCP2 PE=1 SV=2"	"2"	"1"	"2"	"1"	"502"	"57.2"	"5.80"	"358.09"	"3.09"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04516, Pf18016"	"7024"	"ENSG00000135457"	"TFCP2"	"A8K5E9; hsa:7024; Q12800; Q12801; Q9UD75; Q9UD77"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"22.8"	"14.1"	"21.0"	"19.4"	"24.2"	"23.7"	"37.5"	"39.5"	"26.6"	"39.2"	"63.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16658"	"Fascin OS=Homo sapiens OX=9606 GN=FSCN1 PE=1 SV=3"	"3"	"1"	"2"	"1"	"493"	"54.5"	"7.24"	"273.22"	"3.09"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf06268"	"6624"	"ENSG00000075618"	"FSCN1"	"A6NI89; B2RE97; hsa:6624; Q16658; Q96IC5; Q96IH1; Q9BRF1"	"VEGFA-VEGFR2 signaling; Urotensin-II-mediated signaling pathway"	"Interleukin-4 and Interleukin-13 signaling"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6A4"	"Cilia- and flagella-associated protein 20 OS=Homo sapiens OX=9606 GN=CFAP20 PE=1 SV=1"	"6"	"1"	"1"	"1"	"193"	"22.8"	"9.76"	""	"3.09"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	""	"Pf05018"	"29105"	"ENSG00000070761"	"CFAP20"	"hsa:29105; Q9Y6A4"	""	""	"0"	"0"	"47.9"	"27.1"	"35.2"	"35.5"	"44.4"	"48.3"	"123.0"	"113.3"	"87.0"	"176.6"	"242.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16698"	"2,4-dienoyl-CoA reductase, mitochondrial OS=Homo sapiens OX=9606 GN=DECR1 PE=1 SV=1"	"6"	"2"	"3"	"2"	"335"	"36.0"	"9.28"	"702.40"	"3.09"	"2"	"1"	"other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf13561"	"1666"	"ENSG00000104325"	"DECR1"	"B7Z6B8; hsa:1666; Q16698; Q2M304; Q93085"	"Fatty acid beta-oxidation; Fatty acid biosynthesis; VEGFA-VEGFR2 signaling"	"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids"	"4"	"0"	"100.5"	"71.7"	"94.5"	"87.1"	"93.5"	"93.9"	"564.4"	"540.3"	"358.5"	"548.8"	"717.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75487"	"Glypican-4 OS=Homo sapiens OX=9606 GN=GPC4 PE=1 SV=4"	"2"	"1"	"2"	"1"	"556"	"62.4"	"6.68"	"343.79"	"3.09"	"1"	"1"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;signal transduction;other biological processes"	"extracellular matrix;plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf01153"	"2239"	"ENSG00000076716"	"GPC4"	"B2R6J7; B4E2C0; hsa:2239; O75487; Q6ZMA6; Q96L43; Q9NU08; Q9UJN1; Q9UPD9"	"Wnt signaling"	"A tetrasaccharide linker sequence is required for GAG synthesis; HS-GAG biosynthesis; HS-GAG degradation; Defective B4GALT7 causes EDS, progeroid type; Defective B3GAT3 causes JDSSDHD; Defective EXT2 causes exostoses 2; Defective EXT1 causes exostoses 1, TRPS2 and CHDS; Defective B3GALT6 causes EDSP2 and SEMDJL1; Attachment and Entry; Retinoid metabolism and transport"	"11"	"0"	"121.1"	"81.1"	"88.1"	"95.2"	"90.5"	"122.9"	"320.2"	"282.0"	"233.7"	"314.9"	"361.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IWF6"	"Protein DENND6A OS=Homo sapiens OX=9606 GN=DENND6A PE=1 SV=1"	"2"	"1"	"2"	"1"	"608"	"69.5"	"8.27"	"362.05"	"3.09"	"1"	"1"	"other biological processes"	"cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity"	"Pf08616, Pf09794"	"201627"	"ENSG00000174839"	"DENND6A"	"hsa:201627; Q7Z5T4; Q8IWF6; Q8N235; Q8TEG8"	""	"RAB GEFs exchange GTP for GDP on RABs"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61586"	"Transforming protein RhoA OS=Homo sapiens OX=9606 GN=RHOA PE=1 SV=1"	"5"	"1"	"2"	"1"	"193"	"21.8"	"6.10"	"328.83"	"3.08"	"1"	"1"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00071"	"387"	"ENSG00000067560"	"RHOA"	"hsa:387; P06749; P61586; Q53HM4; Q5U024; Q9UDJ0; Q9UEJ4"	"Androgen receptor signaling pathway; Physiological and pathological hypertrophy of the heart; MicroRNAs in cardiomyocyte hypertrophy; Leptin signaling pathway; Pathogenic Escherichia coli infection; AGE/RAGE pathway; Corticotropin-releasing hormone signaling pathway; Spinal cord injury; Alpha 6 beta 4 signaling pathway; Focal adhesion; G protein signaling pathways; Wnt signaling pathway; Hypothetical craniofacial development pathway; Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Wnt signaling pathway and pluripotency; Fibrin complement receptor 3 signaling pathway; Wnt signaling in kidney disease; Chromosomal and microsatellite instability in colorectal cancer ; Ebola virus infection in host; Ras signaling; Pancreatic adenocarcinoma pathway; Wnt signaling; Envelope proteins and their potential roles in EDMD physiopathology; Hippo signaling regulation pathways; Leukocyte-intrinsic Hippo pathway functions; Neural crest cell migration during development; Neural crest cell migration in cancer; Joubert syndrome; Gastrin signaling pathway; Netrin-UNC5B signaling pathway; mBDNF and proBDNF regulation of GABA neurotransmission; MAP3K1 role in promoting and blocking gonadal determination; Airway smooth muscle cell contraction; RAS and bradykinin pathways in COVID-19; Regulation of actin cytoskeleton; GDNF signaling; PtdIns(4,5)P2 in cytokinesis pathway; 2q11.2 copy number variation syndrome; 2q21.1 copy number variation syndrome; G13 signaling pathway; 13q12.12 copy number variation; DNA damage response (only ATM dependent); Serotonin HTR1 group and FOS pathway"	"RHOC GTPase cycle; RHOA GTPase cycle; G alpha (12/13) signalling events; RHO GTPases Activate Formins; Neutrophil degranulation; EPHB-mediated forward signaling; GPVI-mediated activation cascade; PI3K/AKT activation; VEGFA-VEGFR2 Pathway; ERBB2 Regulates Cell Motility; RHO GTPases activate CIT; G beta:gamma signalling through PI3Kgamma; PCP/CE pathway; RHO GTPases Activate Rhotekin and Rhophilins; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; Sema4D mediated inhibition of cell attachment and migration; Ovarian tumor domain proteases; SLIT2:ROBO1 increases RHOA activity; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases; TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition); Axonal growth stimulation; Axonal growth inhibition (RHOA activation); RHO GTPases activate KTN1"	"70"	"0"	"120.2"	"40.8"	"60.2"	"42.1"	"60.2"	"55.7"	"107.3"	"91.5"	"71.1"	"122.2"	"196.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UJX2"	"Cell division cycle protein 23 homolog OS=Homo sapiens OX=9606 GN=CDC23 PE=1 SV=3"	"2"	"1"	"2"	"1"	"597"	"68.8"	"7.02"	"345.47"	"3.07"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf04049"	"8697"	"ENSG00000094880"	"CDC23"	"A8K6E5; B4E3A2; B7WP05; D3DQB7; hsa:8697; O75433; Q53FN2; Q9BS73; Q9UJX2"	"Cell cycle"	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Separation of Sister Chromatids; Inactivation of APC/C via direct inhibition of the APC/C complex; APC-Cdc20 mediated degradation of Nek2A; Senescence-Associated Secretory Phenotype (SASP); Antigen processing: Ubiquitination & Proteasome degradation; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; CDK-mediated phosphorylation and removal of Cdc6; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Regulation of APC/C activators between G1/S and early anaphase; APC/C:Cdc20 mediated degradation of Cyclin B; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; Phosphorylation of the APC/C; Transcriptional Regulation by VENTX; Aberrant regulation of mitotic exit in cancer due to RB1 defects"	"19"	"0"	"19.2"	"14.1"	"19.2"	"15.6"	"18.5"	"21.3"	"45.3"	"30.4"	"27.7"	"47.5"	"56.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92793"	"CREB-binding protein OS=Homo sapiens OX=9606 GN=CREBBP PE=1 SV=3"	"1"	"1"	"2"	"1"	"2442"	"265.2"	"8.53"	"305.58"	"3.07"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00439, Pf00569, Pf02135, Pf02172, Pf06001, Pf08214, Pf09030"	"1387"	"ENSG00000005339"	"CREBBP"	"D3DUC9; hsa:1387; O00147; Q16376; Q4LE28; Q92793"	"Androgen receptor signaling pathway; Angiogenesis; TNF-alpha signaling pathway; Notch signaling; Initiation of transcription and translation elongation at the HIV-1 LTR; IL6 signaling pathway; Pathways affected in adenoid cystic carcinoma; Hematopoietic stem cell gene regulation by GABP alpha/beta complex; VEGFA-VEGFR2 signaling; Wnt signaling pathway and pluripotency; Clear cell renal cell carcinoma pathways; Ebola virus infection in host; Type 2 papillary renal cell carcinoma; Ciliary landscape; Hepatitis B infection; Male infertility; TGF-beta receptor signaling in skeletal dysplasias; Overlap between signal transduction pathways contributing to LMNA laminopathies; 15q13.3 copy number variation syndrome; Urotensin-II-mediated signaling pathway; 15q11q13 copy number variation; TGF-beta receptor signaling; Sudden infant death syndrome (SIDS) susceptibility pathways"	"SARS-CoV-2 activates/modulates innate and adaptive immune responses; SUMOylation of transcription cofactors; Formation of paraxial mesoderm; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Pre-NOTCH Transcription and Translation; NOTCH1 Intracellular Domain Regulates Transcription; Notch-HLH transcription pathway; NOTCH3 Intracellular Domain Regulates Transcription; Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells; NOTCH4 Intracellular Domain Regulates Transcription; RUNX3 regulates NOTCH signaling; Estrogen-dependent gene expression; Attenuation phase; Activation of the TFAP2 (AP-2) family of transcription factors; PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; NPAS4 regulates expression of target genes; Heme signaling; Formation of the beta-catenin:TCF transactivating complex; BMAL1:CLOCK,NPAS2 activates circadian gene expression; Transcriptional activation of mitochondrial biogenesis; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Cytoprotection by HMOX1; Activation of gene expression by SREBF (SREBP); NFE2L2 regulating anti-oxidant/detoxification enzymes; HATs acetylate histones; TP53 Regulates Transcription of Genes Involved in Cytochrome C Release; Nuclear events mediated by NFE2L2; NFE2L2 regulates pentose phosphate pathway genes; FOXO-mediated transcription of cell death genes; Regulation of FOXO transcriptional activity by acetylation; RORA activates gene expression; CD209 (DC-SIGN) signaling; TRAF3-dependent IRF activation pathway; TRAF6 mediated IRF7 activation; Regulation of gene expression by Hypoxia-inducible Factor; RUNX1 regulates transcription of genes involved in differentiation of myeloid cells; LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production"	"64"	"0"	"9.8"	"6.8"	"10.0"	"12.6"	"12.2"	"14.0"	"17.8"	"25.6"	"15.7"	"28.1"	"40.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P27824"	"Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2"	"4"	"2"	"3"	"2"	"592"	"67.5"	"4.60"	"717.00"	"3.06"	"2"	"1"	"protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;translational apparatus;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00262"	"821"	"ENSG00000127022; ENSG00000283777"	"CANX"	"B2R5V8; B4DGP8; B4E2T8; D3DWQ3; D6R9K3; hsa:821; P27824"	"15q11q13 copy number variation"	"Maturation of spike protein; MHC class II antigen presentation; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Interleukin-35 Signalling; Interleukin-27 signaling; Assembly of Viral Components at the Budding Site; Calnexin/calreticulin cycle; Maturation of spike protein"	"9"	"0"	"384.9"	"200.8"	"220.0"	"163.4"	"247.9"	"245.9"	"353.4"	"246.2"	"146.8"	"355.7"	"463.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96J01"	"THO complex subunit 3 OS=Homo sapiens OX=9606 GN=THOC3 PE=1 SV=1"	"3"	"1"	"2"	"1"	"351"	"38.7"	"6.09"	"429.93"	"3.06"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00400, Pf08662, Pf12894"	"84321"	"ENSG00000051596"	"THOC3"	"hsa:84321; Q6NZ53; Q96J01"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"3"	"0"	"82.9"	"52.6"	"79.5"	"71.5"	"78.2"	"77.3"	"164.5"	"129.6"	"88.9"	"179.9"	"262.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q08J23"	"RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2"	"3"	"1"	"2"	"1"	"767"	"86.4"	"6.77"	"312.42"	"3.05"	"1"	"1"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytoskeleton;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01189"	"54888"	"ENSG00000037474"	"NSUN2"	"A8K529; B2RNR4; B3KP09; B4DQW2; G3V1R4; hsa:54888; Q08J23; Q9BVN4; Q9H858; Q9NXD9"	""	"tRNA modification in the nucleus and cytosol"	"1"	"0"	"6.0"	"4.9"	"6.0"	"7.8"	"7.0"	"7.2"	"23.4"	"13.2"	"14.0"	"18.9"	"20.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IYB5"	"Stromal membrane-associated protein 1 OS=Homo sapiens OX=9606 GN=SMAP1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"467"	"50.4"	"8.75"	"304.39"	"3.05"	"1"	"1"	"other biological processes"	"plasma membrane;other membranes;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01412"	"60682"	"ENSG00000112305"	"SMAP1"	"hsa:60682; Q53H70; Q5SYQ2; Q6PK24; Q8IYB5; Q8NDH4; Q96L38; Q96L39; Q9H8X4"	""	""	"0"	"0"	"6.2"	"0.0"	"7.5"	"5.6"	"8.2"	"6.2"	"20.5"	"21.2"	"14.2"	"29.5"	"33.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P41208"	"Centrin-2 OS=Homo sapiens OX=9606 GN=CETN2 PE=1 SV=1"	"12"	"2"	"3"	"2"	"172"	"19.7"	"5.00"	"659.90"	"3.05"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;transport;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf13499"	"1069"	"ENSG00000147400"	"CETN2"	"B2R4T4; hsa:1069; P41208; Q53XW1"	"Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; SUMOylation of DNA damage response and repair proteins; Formation of Incision Complex in GG-NER; DNA Damage Recognition in GG-NER"	"13"	"0"	"133.0"	"71.8"	"119.1"	"120.2"	"107.0"	"145.6"	"280.3"	"388.4"	"233.0"	"373.3"	"551.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30046"	"D-dopachrome decarboxylase OS=Homo sapiens OX=9606 GN=DDT PE=1 SV=3"	"9"	"1"	"1"	"1"	"118"	"12.7"	"7.30"	""	"3.05"	""	"1"	"other metabolic processes;other biological processes"	"non-structural extracellular;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01187"	"1652"	"ENSG00000099977; ENSG00000275003"	"DDT"	"B7Z522; hsa:1652; O00774; O60787; P30046; Q13534"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HD47"	"Ran guanine nucleotide release factor OS=Homo sapiens OX=9606 GN=RANGRF PE=1 SV=1"	"7"	"1"	"2"	"1"	"186"	"20.4"	"4.94"	"318.50"	"3.04"	"1"	"1"	"transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf04603"	"29098"	"ENSG00000108961"	"RANGRF"	"D3DTR6; hsa:29098; Q68DI3; Q9BR68; Q9HD47; Q9HD48; Q9NRU9; Q9P001; Q9P0P2"	""	"Phase 0 - rapid depolarisation"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P54136"	"Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2"	"4"	"1"	"1"	"1"	"660"	"75.3"	"6.68"	""	"3.04"	""	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00750, Pf03485, Pf05746"	"5917"	"ENSG00000113643"	"RARS1"	"B2RBS9; hsa:5917; P54136; Q53GY4; Q9BWA1"	"Amino acid metabolism"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"3"	"0"	"15.7"	"6.5"	"17.4"	"16.8"	"13.8"	"14.1"	"23.7"	"19.3"	"19.8"	"26.1"	"46.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14639"	"Actin-binding LIM protein 1 OS=Homo sapiens OX=9606 GN=ABLIM1 PE=1 SV=3"	"1"	"1"	"2"	"1"	"778"	"87.6"	"8.59"	"279.22"	"3.04"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412, Pf02209, Pf16182"	"3983"	"ENSG00000099204"	"ABLIM1"	"A6NI16; A6NJ06; A8MXA9; B3KVH2; hsa:3983; O14639; Q15039; Q5JVV1; Q5JVV2; Q5T6N2; Q5T6N3; Q5T6N5; Q68CQ9; Q9BUP1"	"Male infertility"	"DCC mediated attractive signaling"	"2"	"0"	"13.2"	"11.1"	"13.6"	"13.1"	"18.1"	"18.7"	"33.3"	"30.0"	"25.0"	"34.8"	"45.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48634"	"Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3"	"2"	"3"	"4"	"3"	"2157"	"228.7"	"9.45"	"1411.37"	"3.03"	"3"	"1"	"other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	""	"Pf07001"	"7916"	"ENSG00000204469; ENSG00000206427; ENSG00000225164; ENSG00000225748; ENSG00000226618; ENSG00000231370; ENSG00000231825"	"PRRC2A"	"B0UX77; B0UZE9; B0UZL3; hsa:7916; O95875; P48634; Q05BK4; Q4LE37; Q5SQ29; Q5SQ30; Q5ST84; Q5STX6; Q5STX7; Q68DW9; Q6P9P7; Q6PIN1; Q8MGQ9; Q96QC6"	""	""	"0"	"0"	"49.2"	"23.8"	"40.1"	"45.4"	"41.2"	"53.5"	"142.5"	"141.6"	"105.8"	"138.2"	"169.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P41227"	"N-alpha-acetyltransferase 10 OS=Homo sapiens OX=9606 GN=NAA10 PE=1 SV=1"	"6"	"1"	"2"	"1"	"235"	"26.4"	"5.64"	"441.03"	"3.02"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00583"	"8260"	"ENSG00000102030"	"NAA10"	"A6NM98; hsa:8260; P41227"	""	""	"0"	"0"	"12.7"	"2.8"	"8.9"	"10.6"	"12.8"	"13.8"	"44.1"	"35.1"	"35.8"	"47.2"	"79.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5JSH3"	"WD repeat-containing protein 44 OS=Homo sapiens OX=9606 GN=WDR44 PE=1 SV=1"	"1"	"1"	"2"	"1"	"913"	"101.3"	"5.45"	"301.83"	"3.02"	"1"	"1"	""	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf00400"	"54521"	"ENSG00000131725"	"WDR44"	"B4DSE9; F8W913; hsa:54521; Q0JS52; Q0JTF3; Q5JSH2; Q5JSH3; Q6ZSC1; Q7Z365; Q7Z3P6; Q8NAU8; Q8NHU5; Q9NUV4"	"Ectoderm differentiation"	""	"1"	"0"	"2.5"	"0.0"	"0.0"	"5.0"	"4.5"	"4.2"	"15.3"	"22.5"	"32.6"	"37.7"	"56.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14320"	"Protein FAM50A OS=Homo sapiens OX=9606 GN=FAM50A PE=1 SV=2"	"3"	"1"	"2"	"1"	"339"	"40.2"	"6.83"	"359.53"	"3.02"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf04921"	"9130"	"ENSG00000071859"	"FAM50A"	"A8KAQ4; B2R997; hsa:9130; Q14320; Q5HY37; Q6PJH5"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"88.6"	"59.3"	"75.8"	"70.8"	"74.3"	"101.7"	"160.8"	"134.6"	"122.7"	"179.1"	"241.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3B9"	"RRP15-like protein OS=Homo sapiens OX=9606 GN=RRP15 PE=1 SV=2"	"4"	"1"	"2"	"1"	"282"	"31.5"	"5.52"	"399.19"	"3.02"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"other cell component"	""	"Pf07890"	"51018"	"ENSG00000067533"	"RRP15"	"hsa:51018; Q9Y3B9"	""	""	"0"	"0"	"8.8"	"7.4"	"8.4"	"10.3"	"8.7"	"12.0"	"25.2"	"21.0"	"19.6"	"32.0"	"42.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L2E3"	"ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1194"	"133.9"	"8.78"	"293.84"	"3.01"	"1"	"1"	"cell organization and biogenesis;developmental processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"22907"	"ENSG00000132153"	"DHX30"	"A8K5F1; hsa:22907; O94965; Q7L2E3; Q7Z753; Q96CH4; Q9NUQ0"	""	""	"0"	"0"	"31.2"	"23.6"	"42.1"	"33.7"	"35.2"	"44.2"	"76.8"	"70.4"	"59.2"	"87.7"	"108.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P10644"	"cAMP-dependent protein kinase type I-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR1A PE=1 SV=1"	"5"	"1"	"2"	"1"	"381"	"43.0"	"5.35"	"379.68"	"3.01"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00027, Pf02197"	"5573"	"ENSG00000108946"	"PRKAR1A"	"hsa:5573; K7ER48; P10644; Q567S7"	"Mesodermal commitment pathway; Myometrial relaxation and contraction pathways; Mesodermal commitment pathway; G protein signaling pathways; Cannabinoid receptor signaling; Lipid metabolism pathway; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; Fragile X syndrome; Cardiomyocyte signaling pathways converging on Titin; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Hedgehog 'off' state; FCGR3A-mediated IL10 synthesis; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; ALK mutants bind TKIs; Signaling by ALK fusions and activated point mutants; Factors involved in megakaryocyte development and platelet production; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Vasopressin regulates renal water homeostasis via Aquaporins; PKA activation; PKA activation in glucagon signalling; DARPP-32 events; CREB1 phosphorylation through the activation of Adenylate Cyclase"	"25"	"0"	"23.0"	"13.3"	"15.3"	"28.0"	"21.4"	"26.9"	"54.4"	"48.4"	"31.0"	"59.6"	"71.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04637"	"Cellular tumor antigen p53 OS=Homo sapiens OX=9606 GN=TP53 PE=1 SV=4"	"4"	"2"	"3"	"2"	"393"	"43.6"	"6.79"	"621.13"	"3.01"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00870, Pf07710, Pf08563, Pf18521"	"7157"	"ENSG00000141510"	"TP53"	"hsa:7157; P04637; Q15086; Q15087; Q15088; Q16535; Q16807; Q16808; Q16809; Q16810; Q16811; Q16848; Q2XN98; Q3LRW1; Q3LRW2; Q3LRW3; Q3LRW4; Q3LRW5; Q86UG1; Q8J016; Q99659; Q9BTM4; Q9HAQ8; Q9NP68; Q9NPJ2; Q9NZD0; Q9UBI2; Q9UQ61"	"AMP-activated protein kinase signaling; miRNA regulation of DNA damage response; miRNAs involved in DNA damage response; Fluoropyrimidine activity; TP53 network; Folate metabolism; Apoptosis modulation and signaling; Cell cycle; Metastatic brain tumor; Glioblastoma signaling pathways; Gastric cancer network 2; Oncostatin M signaling pathway; Spinal cord injury; Retinoblastoma gene in cancer; Amyotrophic lateral sclerosis (ALS); ATM signaling pathway; Apoptosis; Mammary gland development pathway - Involution (Stage 4 of 4); Bladder cancer; Copper homeostasis; RAC1/PAK1/p38/MMP2 pathway; Photodynamic therapy-induced HIF-1 survival signaling; Hepatitis C and hepatocellular carcinoma; Pathways affected in adenoid cystic carcinoma; lncRNA-mediated mechanisms of therapeutic resistance; MAPK signaling pathway; miRNA regulation of p53 pathway in prostate cancer; Wnt signaling pathway and pluripotency; Endometrial cancer; PI3K-Akt signaling pathway; Caloric restriction and aging; Chromosomal and microsatellite instability in colorectal cancer ; Epithelial to mesenchymal transition in colorectal cancer; Non-small cell lung cancer; Breast cancer pathway; Pancreatic adenocarcinoma pathway; Ultraconserved region 339 modulation of tumor suppressor microRNAs in cancer; Ferroptosis; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; MicroRNA network associated with chronic lymphocytic leukemia; G1 to S cell cycle control; Measles virus infection; 22q11.2 copy number variation syndrome; Small cell lung cancer; Head and neck squamous cell carcinoma; Melanoma; Thyroid hormones production and peripheral downstream signaling effects; Netrin-UNC5B signaling pathway; IL-18 signaling pathway; Unfolded protein response; 16p11.2 proximal deletion syndrome; Pentose phosphate pathway in senescent cells; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Glycolysis in senescence; TCA cycle in senescence; Pleural mesothelioma; Lipid metabolism in senescent cells; DYRK1A involvement regarding cell proliferation in brain development; 2q37 copy number variation syndrome; Autophagy in pancreatic ductal adenocarcinoma; 11p11.2 copy number variation syndrome ; A network map of Macrophage-stimulating protein (MSP) signaling; ErbB signaling pathway; DNA damage response; DNA damage response (only ATM dependent)"	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; TP53 Regulates Transcription of DNA Repair Genes; Regulation of PTEN gene transcription; Factors involved in megakaryocyte development and platelet production; TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest; Autodegradation of the E3 ubiquitin ligase COP1; Ub-specific processing proteases; The role of GTSE1 in G2/M progression after G2 checkpoint; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain; Regulation of TP53 Degradation; TP53 Regulates Transcription of Death Receptors and Ligands; Oxidative Stress Induced Senescence; Regulation of TP53 Activity through Phosphorylation; TP53 Regulates Metabolic Genes; Association of TriC/CCT with target proteins during biosynthesis; Interleukin-4 and Interleukin-13 signaling; Pre-NOTCH Transcription and Translation; Oncogene Induced Senescence; Transcriptional Regulation by VENTX; TP53 Regulates Transcription of Caspase Activators and Caspases; Regulation of TP53 Activity through Methylation; G2/M DNA damage checkpoint; Regulation of NF-kappa B signaling; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Activation of PUMA and translocation to mitochondria; TP53 Regulates Transcription of Genes Involved in Cytochrome C Release; TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain; Regulation of TP53 Activity through Association with Co-factors; Ovarian tumor domain proteases; Pyroptosis; SUMOylation of transcription factors; Regulation of TP53 Expression; RUNX3 regulates CDKN1A transcription; Activation of NOXA and translocation to mitochondria; Formation of Senescence-Associated Heterochromatin Foci (SAHF); PI5P Regulates TP53 Acetylation; Transcriptional  activation of  cell cycle inhibitor p21 ; Loss of function of TP53 in cancer due to loss of tetramerization ability"	"107"	"0"	"293.9"	"158.1"	"222.3"	"217.2"	"206.8"	"253.3"	"640.8"	"560.0"	"405.4"	"546.5"	"604.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EY1"	"DnaJ homolog subfamily A member 3, mitochondrial OS=Homo sapiens OX=9606 GN=DNAJA3 PE=1 SV=2"	"3"	"1"	"2"	"1"	"480"	"52.5"	"9.26"	"249.71"	"3.00"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00226, Pf00684, Pf01556"	"9093"	"ENSG00000103423; ENSG00000276726"	"DNAJA3"	"B2RAJ5; B4DI33; E7ES32; hsa:9093; O75472; Q8WUJ6; Q8WXJ3; Q96D76; Q96EY1; Q96IV1; Q9NYH8"	""	""	"0"	"0"	"26.2"	"10.7"	"29.5"	"26.4"	"25.9"	"31.8"	"50.4"	"55.8"	"33.9"	"57.5"	"77.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15118"	"[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial OS=Homo sapiens OX=9606 GN=PDK1 PE=1 SV=1"	"3"	"1"	"2"	"1"	"436"	"49.2"	"8.81"	"265.98"	"3.00"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"mitochondrion"	"kinase activity;other molecular function"	"Pf02518, Pf10436"	"5163"	"ENSG00000152256"	"PDK1"	"B2R6T1; B7Z937; D3DPD8; E9PD65; hsa:5163; Q15118; Q308M4"	"T cell receptor and co-stimulatory signaling; PI3K-AKT-mTOR signaling pathway and therapeutic opportunities in prostate cancer; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; Non-small cell lung cancer; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Aspirin and miRNAs; PKC-gamma calcium signaling pathway in ataxia; Kisspeptin/kisspeptin receptor system in the ovary; TCA cycle in senescence; Pleural mesothelioma; Orexin receptor pathway; Resolvin E1 and resolvin D1 signaling pathways promoting inflammation resolution; Glucose metabolism in triple-negative breast cancer cells; EPO receptor signaling; DNA damage response (only ATM dependent)"	"Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid"	"19"	"0"	"14.0"	"12.1"	"20.0"	"21.9"	"16.8"	"16.8"	"53.0"	"59.9"	"41.9"	"70.0"	"92.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IZ83"	"Aldehyde dehydrogenase family 16 member A1 OS=Homo sapiens OX=9606 GN=ALDH16A1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"802"	"85.1"	"6.79"	"324.99"	"2.99"	"1"	"1"	""	""	"other molecular function"	"Pf00171"	"126133"	"ENSG00000161618"	"ALDH16A1"	"B4DLQ1; C9JBH6; hsa:126133; Q86YF0; Q8IYL4; Q8IZ83; Q8TEI8"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49721"	"Proteasome subunit beta type-2 OS=Homo sapiens OX=9606 GN=PSMB2 PE=1 SV=1"	"8"	"2"	"3"	"2"	"201"	"22.8"	"7.02"	"505.32"	"2.99"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00227"	"5690"	"ENSG00000126067"	"PSMB2"	"D3DPS0; hsa:5690; P31145; P49721; Q9BWZ9"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Separation of Sister Chromatids; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"62"	"0"	"339.7"	"218.1"	"359.5"	"351.4"	"362.4"	"375.7"	"845.9"	"735.2"	"521.2"	"892.3"	"1249.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IUF8"	"Ribosomal oxygenase 2 OS=Homo sapiens OX=9606 GN=RIOX2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"465"	"52.8"	"6.70"	"343.28"	"2.98"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf08007, Pf20514"	"84864"	"ENSG00000170854"	"RIOX2"	"D3DN35; hsa:84864; Q6AHW4; Q6SKS0; Q8IU69; Q8IUF6; Q8IUF7; Q8IUF8; Q96C17; Q96KB0"	""	"HDMs demethylate histones"	"1"	"0"	"22.9"	"16.5"	"18.5"	"21.3"	"17.8"	"26.3"	"122.9"	"132.0"	"86.4"	"132.5"	"151.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95619"	"YEATS domain-containing protein 4 OS=Homo sapiens OX=9606 GN=YEATS4 PE=1 SV=1"	"4"	"1"	"2"	"1"	"227"	"26.5"	"8.41"	"373.18"	"2.98"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03366"	"8089"	"ENSG00000127337"	"YEATS4"	"hsa:8089; O95619; Q9NQD0"	""	"HATs acetylate histones; Activation of the TFAP2 (AP-2) family of transcription factors"	"2"	"0"	"45.3"	"19.6"	"46.2"	"43.1"	"40.7"	"47.0"	"84.7"	"74.6"	"45.7"	"93.9"	"168.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P0CG22"	"Putative dehydrogenase/reductase SDR family member 4-like 1 OS=Homo sapiens OX=9606 GN=DHRS4L1 PE=5 SV=1"	"3"	"1"	"2"	"1"	"281"	"30.6"	"9.77"	"311.83"	"2.98"	"1"	"1"	"other metabolic processes"	"other cytoplasmic organelle"	"other molecular function"	"Pf13561"	""	""	"DHRS4L1"	"P0CG22"	""	""	"0"	"0"	"91.7"	"58.9"	"118.6"	"94.0"	"110.5"	"103.9"	"182.0"	"172.7"	"128.3"	"237.9"	"312.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NPA8"	"Transcription and mRNA export factor ENY2 OS=Homo sapiens OX=9606 GN=ENY2 PE=1 SV=1"	"7"	"1"	"2"	"1"	"101"	"11.5"	"9.33"	"244.30"	"2.98"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf10163"	"56943"	"ENSG00000120533"	"ENY2"	"B2RE52; G3V117; hsa:56943; Q9NPA8"	""	"HATs acetylate histones"	"1"	"0"	"84.6"	"50.9"	"82.7"	"86.2"	"72.1"	"97.8"	"182.2"	"169.1"	"125.0"	"248.1"	"361.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15058"	"Kinesin-like protein KIF14 OS=Homo sapiens OX=9606 GN=KIF14 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1648"	"186.4"	"7.91"	"334.33"	"2.98"	"1"	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225, Pf00498, Pf16183"	"9928"	"ENSG00000118193"	"KIF14"	"hsa:9928; Q14CI8; Q15058; Q4G0A5; Q5T1W3"	""	"RND2 GTPase cycle; RND1 GTPase cycle; RHO GTPases activate CIT"	"3"	"0"	"12.3"	"7.4"	"18.5"	"20.3"	"15.2"	"19.3"	"37.7"	"51.2"	"55.2"	"87.7"	"116.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96GQ7"	"Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2"	"3"	"2"	"3"	"2"	"796"	"89.8"	"9.28"	"516.26"	"2.97"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271"	"55661"	""	"DDX27"	"A0AVB6; B7ZLY1; hsa:55661; Q5VXM7; Q8WYG4; Q969N7; Q96F57; Q96GQ7; Q96L97; Q9BWY9; Q9BXF0; Q9H990; Q9NWU3; Q9P0C2; Q9UGD6"	""	""	"0"	"0"	"8.5"	"6.7"	"7.3"	"7.8"	"4.0"	"8.6"	"23.1"	"25.3"	"17.3"	"19.2"	"23.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H7B2"	"Ribosome production factor 2 homolog OS=Homo sapiens OX=9606 GN=RPF2 PE=1 SV=2"	"6"	"1"	"2"	"1"	"306"	"35.6"	"9.99"	"283.87"	"2.97"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf04427"	"84154"	"ENSG00000197498"	"RPF2"	"hsa:84154; Q5VXN1; Q8N4A1; Q9H7B2"	""	""	"0"	"0"	"9.4"	"8.6"	"8.3"	"11.2"	"9.1"	"12.5"	"33.1"	"25.8"	"19.3"	"30.3"	"35.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EV8"	"Dysbindin OS=Homo sapiens OX=9606 GN=DTNBP1 PE=1 SV=1"	"5"	"1"	"2"	"1"	"351"	"39.5"	"4.67"	"440.06"	"2.97"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	""	"Pf04440"	"84062"	"ENSG00000047579"	"DTNBP1"	"A8K3V3; hsa:84062; Q5THY3; Q5THY4; Q96EV8; Q96NV2; Q9H0U2; Q9H3J5"	"Alstrom syndrome"	"Golgi Associated Vesicle Biogenesis"	"2"	"0"	"16.2"	"8.2"	"9.1"	"9.7"	"10.2"	"16.0"	"24.6"	"22.0"	"20.9"	"23.5"	"27.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6NYC1"	"Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 OS=Homo sapiens OX=9606 GN=JMJD6 PE=1 SV=1"	"3"	"1"	"2"	"1"	"403"	"46.4"	"8.69"	"306.85"	"2.96"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02373"	"23210"	"ENSG00000070495"	"JMJD6"	"B3KMN8; B4DGX1; hsa:23210; Q6NYC1; Q86VY0; Q8IUM5; Q9Y4E2"	""	"HDMs demethylate histones"	"1"	"0"	"7.5"	"8.4"	"11.6"	"14.4"	"16.2"	"15.4"	"95.1"	"76.2"	"37.3"	"56.0"	"49.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60613"	"Selenoprotein F OS=Homo sapiens OX=9606 GN=SELENOF PE=1 SV=4"	"8"	"1"	"2"	"1"	"165"	"18.1"	"5.03"	"306.53"	"2.96"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"ER/Golgi"	"other molecular function"	"Pf08806"	"9403"	"ENSG00000183291"	"SELENOF"	"A0A0B4J1S4; hsa:9403; O60613; Q4GZG7; Q8WU00; Q9BS64; Q9GZW0; Q9NR01"	"Selenium metabolism / selenoproteins; Selenium micronutrient network"	""	"2"	"0"	"14.6"	"11.1"	"15.3"	"16.1"	"13.2"	"15.5"	"31.8"	"31.4"	"21.6"	"35.4"	"47.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14578"	"Citron Rho-interacting kinase OS=Homo sapiens OX=9606 GN=CIT PE=1 SV=2"	"1"	"1"	"2"	"1"	"2027"	"231.3"	"6.57"	"271.31"	"2.96"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf00169, Pf00780"	"11113"	"ENSG00000122966"	"CIT"	"hsa:11113; O14578; Q2M5E1; Q6XUH8; Q86UQ9; Q9UPZ7"	"Pleural mesothelioma; G13 signaling pathway"	"RHOC GTPase cycle; RHOA GTPase cycle; RAC1 GTPase cycle; RHOB GTPase cycle; RHO GTPases activate CIT"	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NYR9"	"NF-kappa-B inhibitor-interacting Ras-like protein 2 OS=Homo sapiens OX=9606 GN=NKIRAS2 PE=1 SV=1"	"6"	"1"	"2"	"1"	"191"	"21.5"	"8.05"	"362.65"	"2.96"	"1"	"1"	"stress response;developmental processes;signal transduction;other biological processes"	"other cell component"	"other molecular function"	"Pf00071"	"28511"	"ENSG00000168256"	"NKIRAS2"	"A6NCZ5; B3KNN0; B4DNM3; hsa:28511; Q6PK52; Q96KC7; Q9NSX1; Q9NYR9"	""	"RIP-mediated NFkB activation via ZBP1; TAK1-dependent IKK and NF-kappa-B activation  ; TRAF6 mediated NF-kB activation"	"3"	"0"	"8.0"	"3.2"	"7.9"	"4.4"	"6.5"	"7.6"	"17.2"	"17.7"	"14.9"	"36.4"	"34.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94913"	"Pre-mRNA cleavage complex 2 protein Pcf11 OS=Homo sapiens OX=9606 GN=PCF11 PE=1 SV=3"	"1"	"1"	"1"	"1"	"1555"	"172.9"	"8.48"	""	"2.96"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04818"	"51585"	"ENSG00000165494"	"PCF11"	"A6H8W7; hsa:51585; O43671; O94913; Q6P0X8"	""	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; RNA polymerase II transcribes snRNA genes; Processing of Intronless Pre-mRNAs"	"5"	"0"	"14.1"	"13.4"	"28.1"	"26.8"	"21.4"	"17.2"	"40.3"	"41.7"	"36.8"	"48.9"	"73.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14980"	"Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1071"	"123.3"	"6.06"	"382.76"	"2.95"	"1"	"1"	"other metabolic processes;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03810, Pf08389, Pf08767, Pf18777, Pf18784, Pf18787"	"7514"	"ENSG00000082898"	"XPO1"	"A6NL14; A8K1K5; D6W5E2; hsa:7514; O14980; Q63HP8; Q68CP3; Q99433"	"eIF5A regulation in response to inhibition of the nuclear export system; 22q11.2 copy number variation syndrome"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; MAPK6/MAPK4 signaling; Deactivation of the beta-catenin transactivating complex; NPAS4 regulates expression of target genes; Rev-mediated nuclear export of HIV RNA; NEP/NS2 Interacts with the Cellular Export Machinery; Heme signaling; Estrogen-dependent nuclear events downstream of ESR-membrane signaling; Downregulation of TGF-beta receptor signaling; HuR (ELAVL1) binds and stabilizes mRNA; Cyclin A/B1/B2 associated events during G2/M transition"	"18"	"0"	"14.4"	"18.3"	"14.4"	"13.0"	"18.4"	"18.7"	"21.2"	"19.6"	"12.9"	"33.6"	"34.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00541"	"Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1"	"2"	"1"	"2"	"1"	"588"	"68.0"	"7.33"	"312.14"	"2.94"	"1"	"1"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf06732, Pf16589"	"23481"	"ENSG00000100029"	"PES1"	"hsa:23481; O00541; Q6IC29"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"20.0"	"9.6"	"17.7"	"18.4"	"23.1"	"15.8"	"55.8"	"50.3"	"40.6"	"62.0"	"80.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14147"	"Probable ATP-dependent RNA helicase DHX34 OS=Homo sapiens OX=9606 GN=DHX34 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1143"	"128.0"	"7.56"	"305.84"	"2.94"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	""	"other molecular function"	"Pf00271, Pf04408, Pf07717"	"9704"	"ENSG00000134815"	"DHX34"	"B4DMY8; hsa:9704; Q14147"	""	""	"0"	"0"	"42.1"	"25.8"	"41.1"	"37.8"	"34.7"	"51.4"	"97.5"	"85.4"	"65.3"	"107.3"	"144.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00441"	"Superoxide dismutase [Cu-Zn] OS=Homo sapiens OX=9606 GN=SOD1 PE=1 SV=2"	"6"	"1"	"2"	"1"	"154"	"15.9"	"6.13"	"260.53"	"2.94"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"non-structural extracellular;cytosol;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00080"	"6647"	"ENSG00000142168"	"SOD1"	"A6NHJ0; D3DSE4; hsa:6647; P00441; Q16669; Q16711; Q16838; Q16839; Q16840; Q6NR85"	"Selenium micronutrient network; Vitamin B12 metabolism; Folate metabolism; AGE/RAGE pathway; Dopamine metabolism; Amyotrophic lateral sclerosis (ALS); Trans-sulfuration, one-carbon metabolism and related pathways; Copper homeostasis; Physico-chemical features and toxicity-associated pathways; Oxidative stress response; Extracellular vesicles in the crosstalk of cardiac cells; Arsenic metabolism and reactive oxygen species generation"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Platelet degranulation ; Detoxification of Reactive Oxygen Species"	"15"	"0"	"21.3"	"17.4"	"25.1"	"22.1"	"26.2"	"32.1"	"64.0"	"62.8"	"38.9"	"64.5"	"88.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9GZN8"	"UPF0687 protein C20orf27 OS=Homo sapiens OX=9606 GN=C20orf27 PE=1 SV=3"	"8"	"1"	"2"	"1"	"174"	"19.3"	"6.84"	"246.43"	"2.94"	"1"	"1"	"other metabolic processes;other biological processes"	"non-structural extracellular"	"other molecular function"	"Pf15006"	"54976"	"ENSG00000101220"	"ADISSP"	"A8K4J0; D3DVX8; hsa:54976; Q5JX81; Q9GZN8; Q9NWX3"	""	""	"0"	"0"	"55.9"	"32.1"	"51.5"	"37.7"	"37.4"	"49.8"	"63.0"	"57.3"	"39.8"	"75.4"	"134.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14936"	"Peripheral plasma membrane protein CASK OS=Homo sapiens OX=9606 GN=CASK PE=1 SV=3"	"1"	"1"	"2"	"1"	"926"	"105.1"	"6.43"	"312.41"	"2.93"	"1"	"1"	"cell adhesion;protein metabolism;other metabolic processes;transport;other biological processes"	"extracellular matrix;plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf00018, Pf00069, Pf00595, Pf00625, Pf02828"	"8573"	"ENSG00000147044"	"CASK"	"A6NES1; B7ZKY0; hsa:8573; O14936; O43215; Q17RI4; Q59HA0; Q5VT16; Q5VT17; Q5VT18; Q5VT19; Q66T42; Q9BYH6; Q9NYB2; Q9NYB3"	"Parkin-ubiquitin proteasomal system pathway; Splicing factor NOVA regulated synaptic proteins"	"Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Assembly and cell surface presentation of NMDA receptors; Nephrin family interactions; Neurexins and neuroligins; Dopamine Neurotransmitter Release Cycle; Syndecan interactions"	"9"	"0"	"34.2"	"19.7"	"33.2"	"25.0"	"30.7"	"35.1"	"53.6"	"49.6"	"39.9"	"70.4"	"86.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q0ZGT2"	"Nexilin OS=Homo sapiens OX=9606 GN=NEXN PE=1 SV=1"	"1"	"1"	"2"	"1"	"675"	"80.6"	"5.33"	"277.63"	"2.93"	"1"	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf07679"	"91624"	"ENSG00000162614"	"NEXN"	"A0PJ84; B4DPZ7; hsa:91624; Q0D2H2; Q0ZGT2; Q14CC2; Q14CC3; Q16081; Q7Z2X0; Q96DL0; Q9Y2V1"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"85.1"	"62.2"	"96.1"	"93.8"	"108.6"	"93.5"	"165.9"	"166.6"	"139.4"	"168.5"	"226.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96MF7"	"E3 SUMO-protein ligase NSE2 OS=Homo sapiens OX=9606 GN=NSMCE2 PE=1 SV=2"	"4"	"1"	"2"	"1"	"247"	"27.9"	"7.74"	"367.63"	"2.93"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf11789"	"286053"	"ENSG00000156831"	"NSMCE2"	"hsa:286053; Q8N549; Q96MF7"	""	"SUMOylation of DNA damage response and repair proteins"	"1"	"0"	"19.5"	"14.9"	"20.5"	"15.0"	"15.4"	"20.2"	"68.2"	"72.7"	"56.6"	"75.3"	"84.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30040"	"Endoplasmic reticulum resident protein 29 OS=Homo sapiens OX=9606 GN=ERP29 PE=1 SV=4"	"4"	"1"	"2"	"1"	"261"	"29.0"	"7.31"	"322.46"	"2.93"	"1"	"1"	"protein metabolism;other metabolic processes;transport;other biological processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf07749, Pf07912"	"10961"	"ENSG00000089248"	"ERP29"	"C9J183; hsa:10961; P30040; Q3MJC3; Q6FHT4"	""	""	"0"	"0"	"33.7"	"31.1"	"40.4"	"25.1"	"32.7"	"40.0"	"66.7"	"59.6"	"48.7"	"83.4"	"115.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IWI9"	"MAX gene-associated protein OS=Homo sapiens OX=9606 GN=MGA PE=1 SV=4"	"0"	"1"	"2"	"1"	"3065"	"336.0"	"6.90"	"325.61"	"2.93"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00010, Pf00907, Pf16059"	"23269"	"ENSG00000174197"	"MGA"	"B9EGR5; E7ENI0; F5H7K2; hsa:23269; Q8IWI9; Q9H8R3; Q9H9N7; Q9UG69; Q9Y4E9"	"Pathways affected in adenoid cystic carcinoma"	"Transcriptional Regulation by E2F6"	"2"	"0"	"15.7"	"10.7"	"12.0"	"14.8"	"18.5"	"17.3"	"34.4"	"36.9"	"29.7"	"39.7"	"64.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75531"	"Barrier-to-autointegration factor OS=Homo sapiens OX=9606 GN=BANF1 PE=1 SV=1"	"13"	"1"	"2"	"1"	"89"	"10.1"	"6.09"	"379.23"	"2.92"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02961"	"8815"	"ENSG00000175334"	"BANF1"	"hsa:8815; O60558; O75531; Q6FGG7"	"Envelope proteins and their potential roles in EDMD physiopathology; Familial partial lipodystrophy; Progeria-associated lipodystrophy"	"Vpr-mediated nuclear import of PICs; 2-LTR circle formation; Integration of viral DNA into host genomic DNA; Autointegration results in viral DNA circles; APOBEC3G mediated resistance to HIV-1 infection; Nuclear Envelope Breakdown; Initiation of Nuclear Envelope (NE) Reformation"	"11"	"0"	"36.4"	"27.8"	"34.4"	"28.0"	"42.5"	"46.5"	"72.4"	"72.6"	"76.6"	"136.1"	"155.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6UB99"	"Ankyrin repeat domain-containing protein 11 OS=Homo sapiens OX=9606 GN=ANKRD11 PE=1 SV=3"	"0"	"1"	"2"	"1"	"2663"	"297.7"	"7.11"	"281.92"	"2.91"	"1"	"1"	"developmental processes;other biological processes"	"cytosol;nucleus"	""	"Pf12796"	"29123"	"ENSG00000167522"	"ANKRD11"	"hsa:29123; Q6NTG1; Q6QMF8; Q6UB99"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6IN85"	"Serine/threonine-protein phosphatase 4 regulatory subunit 3A OS=Homo sapiens OX=9606 GN=PPP4R3A PE=1 SV=1"	"1"	"1"	"2"	"1"	"833"	"95.3"	"4.94"	"276.45"	"2.91"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity"	"Pf04802"	"55671"	"ENSG00000100796"	"PPP4R3A"	"hsa:55671; Q69YK6; Q6IN85; Q86U23; Q86YI7; Q8IVG1; Q9H3F1; Q9H7U8; Q9NV01; Q9NWP1"	"16p11.2 proximal deletion syndrome"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NBL1"	"Protein O-glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=POGLUT1 PE=1 SV=1"	"3"	"1"	"2"	"1"	"392"	"46.2"	"8.72"	"274.34"	"2.90"	"1"	"1"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf05686"	"56983"	"ENSG00000163389"	"POGLUT1"	"B2RD13; hsa:56983; Q53GJ4; Q8N2T1; Q8NBL1"	""	"Pre-NOTCH Processing in the Endoplasmic Reticulum"	"1"	"0"	"7.0"	"8.5"	"7.6"	"7.3"	"5.2"	"11.5"	"24.8"	"23.2"	"16.5"	"41.1"	"65.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16718"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 OS=Homo sapiens OX=9606 GN=NDUFA5 PE=1 SV=3"	"9"	"1"	"1"	"1"	"116"	"13.5"	"5.99"	""	"2.90"	""	"1"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf04716"	"4698"	"ENSG00000128609"	"NDUFA5"	"B2RD98; hsa:4698; Q16718; Q5H9R2; Q6IRX7"	"Electron transport chain: OXPHOS system in mitochondria; Ciliary landscape; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis; RHOG GTPase cycle"	"7"	"0"	"29.8"	"14.0"	"30.3"	"24.7"	"27.7"	"29.7"	"58.2"	"42.4"	"33.9"	"68.2"	"72.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04844"	"Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Homo sapiens OX=9606 GN=RPN2 PE=1 SV=3"	"3"	"1"	"2"	"1"	"631"	"69.2"	"5.69"	"367.13"	"2.89"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;ER/Golgi;nucleus;other cytoplasmic organelle"	"translation activity"	"Pf05817"	"6185"	"ENSG00000118705"	"RPN2"	"hsa:6185; P04844; Q5JYR6; Q6IBA5; Q96E21; Q9BUQ3; Q9UBE1"	"Proteasome degradation; N-glycan biosynthesis"	"SRP-dependent cotranslational protein targeting to membrane; Asparagine N-linked glycosylation; Maturation of spike protein"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BYD3"	"39S ribosomal protein L4, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL4 PE=1 SV=1"	"9"	"2"	"3"	"2"	"311"	"34.9"	"9.72"	"607.37"	"2.89"	"2"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00573"	"51073"	"ENSG00000105364"	"MRPL4"	"A6NNV7; hsa:51073; Q9BW07; Q9BYD3; Q9H4N2; Q9Y317"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"68.9"	"38.9"	"77.9"	"52.5"	"74.1"	"72.6"	"97.4"	"97.2"	"68.4"	"100.2"	"154.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05204"	"Non-histone chromosomal protein HMG-17 OS=Homo sapiens OX=9606 GN=HMGN2 PE=1 SV=3"	"24"	"2"	"3"	"2"	"90"	"9.4"	"9.99"	"578.90"	"2.89"	"2"	"1"	"cell organization and biogenesis;stress response;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01101"	"3151"	"ENSG00000198830"	"HMGN2"	"hsa:3151; P05204; Q0VGD5; Q6FGI5; Q96C64"	""	""	"0"	"0"	"47.5"	"19.0"	"36.4"	"93.6"	"46.5"	"54.2"	"485.2"	"340.1"	"218.8"	"354.0"	"343.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L9L4"	"MOB kinase activator 1B OS=Homo sapiens OX=9606 GN=MOB1B PE=1 SV=3"	"5"	"1"	"2"	"1"	"216"	"25.1"	"6.73"	"350.70"	"2.88"	"1"	"1"	"signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf03637"	"92597"	"ENSG00000173542"	"MOB1B"	"B2R8U6; B4DRY3; hsa:92597; Q7L9L4; Q8IY23"	"Pleural mesothelioma"	"Signaling by Hippo"	"2"	"0"	"23.9"	"9.4"	"19.6"	"17.7"	"17.2"	"17.8"	"25.6"	"25.2"	"21.1"	"32.8"	"64.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6PI98"	"INO80 complex subunit C OS=Homo sapiens OX=9606 GN=INO80C PE=1 SV=1"	"6"	"1"	"2"	"1"	"192"	"20.6"	"10.02"	"314.65"	"2.87"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus"	""	"Pf08265"	"125476"	"ENSG00000153391"	"INO80C"	"B4DUI4; E9PCS7; hsa:125476; Q6PI98; Q86WR1; Q8N994"	""	"UCH proteinases; DNA Damage Recognition in GG-NER"	"2"	"0"	"35.8"	"20.5"	"29.9"	"25.3"	"32.3"	"46.1"	"63.2"	"51.1"	"32.8"	"60.5"	"85.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NYV4"	"Cyclin-dependent kinase 12 OS=Homo sapiens OX=9606 GN=CDK12 PE=1 SV=2"	"1"	"1"	"1"	"1"	"1490"	"164.1"	"9.44"	""	"2.87"	""	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"51755"	"ENSG00000167258"	"CDK12"	"A7E2B2; B4DYX4; B9EIQ6; hsa:51755; O94978; Q9NYV4"	"17q12 copy number variation syndrome"	"TP53 Regulates Transcription of DNA Repair Genes"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31949"	"Protein S100-A11 OS=Homo sapiens OX=9606 GN=S100A11 PE=1 SV=2"	"10"	"1"	"2"	"1"	"105"	"11.7"	"7.12"	"299.81"	"2.87"	"1"	"1"	"signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00036, Pf01023"	"6282"	"ENSG00000163191"	"S100A11"	"hsa:6282; P31949; Q5VTK0"	""	"Neutrophil degranulation"	"1"	"0"	"14.4"	"12.7"	"33.9"	"13.5"	"21.1"	"20.7"	"23.2"	"25.8"	"17.3"	"32.2"	"29.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y617"	"Phosphoserine aminotransferase OS=Homo sapiens OX=9606 GN=PSAT1 PE=1 SV=2"	"3"	"1"	"2"	"1"	"370"	"40.4"	"7.66"	"249.83"	"2.86"	"1"	"1"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00266"	"29968"	"ENSG00000135069"	"PSAT1"	"hsa:29968; Q5T7G5; Q5T7G6; Q96AW2; Q9BQ12; Q9Y617"	"Trans-sulfuration, one-carbon metabolism and related pathways; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Male infertility; Neuroinflammation and glutamatergic signaling; Amino acid metabolism in triple-negative breast cancer cells"	"Serine biosynthesis"	"7"	"0"	"32.3"	"20.5"	"33.0"	"15.1"	"28.8"	"23.6"	"41.8"	"25.9"	"20.2"	"43.5"	"50.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NR33"	"DNA polymerase epsilon subunit 4 OS=Homo sapiens OX=9606 GN=POLE4 PE=1 SV=2"	"9"	"1"	"1"	"1"	"117"	"12.2"	"4.92"	""	"2.86"	""	"1"	"DNA metabolism;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00808"	"56655"	"ENSG00000115350"	"POLE4"	"hsa:56655; Q53TR2; Q9NR33"	"Pyrimidine metabolism; Base excision repair; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Activation of the pre-replicative complex; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; DNA replication initiation; Gap-filling DNA repair synthesis and ligation in GG-NER"	"16"	"0"	"17.3"	"9.0"	"8.9"	"9.5"	"11.1"	"13.4"	"24.4"	"25.7"	"27.3"	"46.8"	"65.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00401"	"Neural Wiskott-Aldrich syndrome protein OS=Homo sapiens OX=9606 GN=WASL PE=1 SV=2"	"2"	"1"	"2"	"1"	"505"	"54.8"	"7.93"	"367.48"	"2.86"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity"	"Pf00568, Pf00786, Pf02205"	"8976"	"ENSG00000106299"	"WASL"	"A1JUI9; hsa:8976; O00401; Q7Z746"	"Pathogenic Escherichia coli infection; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; Chemokine signaling pathway; G13 signaling pathway"	"Clathrin-mediated endocytosis; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHO GTPases Activate WASPs and WAVEs; RHOJ GTPase cycle; RHOV GTPase cycle; NOSTRIN mediated eNOS trafficking; Nephrin family interactions; EPHB-mediated forward signaling; DCC mediated attractive signaling"	"17"	"0"	"51.3"	"31.6"	"43.7"	"39.2"	"34.9"	"55.9"	"117.3"	"125.4"	"142.2"	"217.9"	"345.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5JSZ5"	"Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2"	"1"	"1"	"1"	"1"	"2229"	"242.8"	"8.34"	""	"2.85"	""	"1"	"other biological processes"	""	""	"Pf07001"	"84726"	"ENSG00000288701"	"PRRC2B"	"hsa:84726; O60270; Q5JSZ5; Q5JSZ7; Q66VZ2; Q68CR0; Q96EI9; Q9H683"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95861"	"3'(2'),5'-bisphosphate nucleotidase 1 OS=Homo sapiens OX=9606 GN=BPNT1 PE=1 SV=1"	"7"	"1"	"1"	"1"	"308"	"33.4"	"5.69"	""	"2.85"	""	"1"	"other metabolic processes;developmental processes"	"cytosol"	"other molecular function"	"Pf00459"	"10380"	"ENSG00000162813"	"BPNT1"	"A8K7C8; B4DPS5; B4DUS9; D3DTA9; hsa:10380; O95861; Q8WVL5; Q9UGJ3"	""	"Cytosolic sulfonation of small molecules"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82930"	"28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2"	"4"	"1"	"2"	"1"	"218"	"25.6"	"9.98"	"336.21"	"2.84"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf16053"	"65993"	"ENSG00000074071"	"MRPS34"	"hsa:65993; P82930; Q9BVI7"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"146.0"	"98.5"	"120.5"	"110.0"	"129.5"	"135.5"	"214.6"	"203.5"	"152.4"	"227.3"	"289.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UQR0"	"Sex comb on midleg-like protein 2 OS=Homo sapiens OX=9606 GN=SCML2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"700"	"77.2"	"8.54"	"276.20"	"2.84"	"1"	"1"	"other biological processes"	"nucleus"	""	"Pf00536, Pf02820, Pf12140, Pf17208"	"10389"	"ENSG00000102098"	"SCML2"	"hsa:10389; Q5JXE6; Q86U98; Q8IWD0; Q8NDP2; Q9UGC5; Q9UQR0"	""	""	"0"	"0"	"7.9"	"3.1"	"5.1"	"3.7"	"8.2"	"8.5"	"13.9"	"15.7"	"11.8"	"20.6"	"19.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30044"	"Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4"	"4"	"1"	"2"	"1"	"214"	"22.1"	"8.70"	"367.71"	"2.84"	"1"	"1"	"other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf08534"	"25824"	"ENSG00000126432"	"PRDX5"	"A6NC19; A6NG06; B7ZLJ4; B7ZVW3; hsa:25824; P30044; Q14CK0; Q6IAF2; Q9UBU5; Q9UJU4; Q9UKX4"	"Selenium micronutrient network"	""	"1"	"0"	"165.3"	"100.9"	"126.3"	"98.5"	"125.2"	"131.1"	"156.9"	"132.3"	"104.1"	"167.9"	"258.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UIG0"	"Tyrosine-protein kinase BAZ1B OS=Homo sapiens OX=9606 GN=BAZ1B PE=1 SV=2"	"1"	"1"	"2"	"1"	"1483"	"170.8"	"8.48"	"303.21"	"2.84"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00439, Pf00628, Pf10537, Pf15612, Pf15613"	"9031"	"ENSG00000009954"	"BAZ1B"	"B9EGK3; D3DXE9; hsa:9031; O95039; O95247; O95277; Q6P1K4; Q86UJ6; Q9UIG0"	"IL-18 signaling pathway; 7q11.23 copy number variation syndrome; 10q11.21q11.23 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"	"5"	"0"	"6.1"	"7.1"	"9.2"	"6.2"	"7.5"	"11.5"	"22.5"	"24.2"	"14.0"	"27.6"	"28.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50402"	"Emerin OS=Homo sapiens OX=9606 GN=EMD PE=1 SV=1"	"5"	"1"	"2"	"1"	"254"	"29.0"	"5.50"	"371.30"	"2.84"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity"	"Pf03020"	"2010"	"ENSG00000102119"	"EMD"	"hsa:2010; P50402; Q6FI02"	"Arrhythmogenic right ventricular cardiomyopathy; Envelope proteins and their potential roles in EDMD physiopathology; Influence of laminopathies on Wnt signaling"	"Initiation of Nuclear Envelope (NE) Reformation; Depolymerization of the Nuclear Lamina; RHOG GTPase cycle; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOD GTPase cycle; Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"	"12"	"0"	"93.4"	"73.0"	"70.1"	"67.7"	"71.9"	"81.5"	"98.5"	"102.5"	"63.2"	"113.1"	"151.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WWM7"	"Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2"	"1"	"1"	"2"	"1"	"1075"	"113.3"	"8.59"	"287.68"	"2.84"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf06741, Pf07145, Pf14438"	"11273"	"ENSG00000168488"	"ATXN2L"	"A8K1R6; B9EGM2; E9PAR9; hsa:11273; O95135; Q63ZY4; Q6NVJ8; Q6PJW6; Q8IU61; Q8IU95; Q8WWM3; Q8WWM4; Q8WWM5; Q8WWM6; Q8WWM7; Q99703"	"16p11.2 distal deletion syndrome"	""	"1"	"0"	"31.9"	"28.0"	"27.1"	"22.0"	"28.2"	"40.2"	"73.4"	"75.6"	"57.7"	"78.8"	"75.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14773"	"Tripeptidyl-peptidase 1 OS=Homo sapiens OX=9606 GN=TPP1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"563"	"61.2"	"6.48"	"405.05"	"2.83"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00082, Pf09286"	"1200"	"ENSG00000166340"	"TPP1"	"hsa:1200; O14773; Q53HT1; Q5JAK6; Q6UX56; Q71JP6; Q96C37"	"VEGFA-VEGFR2 signaling"	"XBP1(S) activates chaperone genes"	"2"	"0"	"21.5"	"21.6"	"24.8"	"21.0"	"23.8"	"25.6"	"42.5"	"48.1"	"37.2"	"54.3"	"68.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95336"	"6-phosphogluconolactonase OS=Homo sapiens OX=9606 GN=PGLS PE=1 SV=2"	"3"	"1"	"2"	"1"	"258"	"27.5"	"6.05"	"239.70"	"2.83"	"1"	"1"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf01182"	"25796"	"ENSG00000130313"	"PGLS"	"hsa:25796; O95336"	"Pentose phosphate metabolism"	"Pentose phosphate pathway"	"2"	"0"	"72.8"	"44.7"	"71.1"	"58.1"	"84.1"	"75.0"	"95.6"	"94.3"	"69.1"	"120.4"	"143.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96KP4"	"Cytosolic non-specific dipeptidase OS=Homo sapiens OX=9606 GN=CNDP2 PE=1 SV=2"	"4"	"1"	"2"	"1"	"475"	"52.8"	"5.97"	"398.99"	"2.83"	"1"	"1"	"protein metabolism"	"cytosol;nucleus"	"other molecular function"	"Pf01546, Pf07687"	"55748"	"ENSG00000133313"	"CNDP2"	"B3KUG4; hsa:55748; Q8WY59; Q96KP4; Q9BQ94; Q9NVB4; V9HWE5"	""	"Glutathione synthesis and recycling; Paracetamol ADME"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02880"	"DNA topoisomerase 2-beta OS=Homo sapiens OX=9606 GN=TOP2B PE=1 SV=3"	"1"	"1"	"2"	"1"	"1626"	"183.2"	"8.00"	"290.20"	"2.82"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00204, Pf00521, Pf01751, Pf02518, Pf08070, Pf16898"	"7155"	"ENSG00000077097"	"TOP2B"	"hsa:7155; Q02880; Q13600; Q9UMG8; Q9UQP8"	""	"SUMOylation of DNA replication proteins"	"1"	"0"	"21.8"	"16.7"	"22.5"	"18.4"	"22.6"	"23.8"	"76.8"	"66.9"	"43.9"	"84.3"	"107.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08243"	"Asparagine synthetase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=ASNS PE=1 SV=4"	"2"	"1"	"2"	"1"	"561"	"64.3"	"6.86"	"304.69"	"2.82"	"1"	"1"	"other metabolic processes;stress response;other biological processes"	"cytosol"	"other molecular function"	"Pf00733, Pf13537"	"440"	"ENSG00000070669"	"ASNS"	"A4D1I8; B4DXZ1; B7ZAA9; D6W5R3; E9PCI3; E9PCX6; hsa:440; P08184; P08243; Q15666; Q549T9; Q96HD0"	"Photodynamic therapy-induced unfolded protein response; Amino acid metabolism"	"Aspartate and asparagine metabolism; Response of EIF2AK1 (HRI) to heme deficiency; ATF4 activates genes in response to endoplasmic reticulum  stress; Response of EIF2AK4 (GCN2) to amino acid deficiency"	"6"	"0"	"68.4"	"65.5"	"75.6"	"64.3"	"80.9"	"79.2"	"108.4"	"99.5"	"82.3"	"114.6"	"161.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6PRD1"	"Probable G-protein coupled receptor 179 OS=Homo sapiens OX=9606 GN=GPR179 PE=1 SV=2"	"1"	"1"	"1"	"1"	"2367"	"257.2"	"5.71"	""	"2.82"	""	"1"	"signal transduction;other biological processes"	"plasma membrane;other membranes"	"other molecular function"	"Pf00003"	"440435"	"ENSG00000276469"	"GPR179"	"hsa:440435; Q6PRD1"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z478"	"ATP-dependent RNA helicase DHX29 OS=Homo sapiens OX=9606 GN=DHX29 PE=1 SV=2"	"2"	"2"	"3"	"2"	"1369"	"155.1"	"8.09"	"669.25"	"2.81"	"2"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"54505"	"ENSG00000067248"	"DHX29"	"hsa:54505; O75549; Q63HN0; Q63HN3; Q7Z478; Q8IWW2; Q8N3A1; Q9UMH2"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"21.7"	"15.4"	"20.4"	"18.5"	"24.2"	"20.6"	"79.7"	"69.7"	"65.9"	"87.2"	"115.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NR56"	"Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"388"	"41.8"	"8.90"	"333.10"	"2.81"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00642, Pf14608"	"4154"	"ENSG00000152601"	"MBNL1"	"E9PBW7; hsa:4154; O43311; O43797; Q86UV8; Q86UV9; Q96P92; Q96RE3; Q9NR56"	"Adipogenesis"	""	"1"	"0"	"37.1"	"18.7"	"34.0"	"31.7"	"35.2"	"47.9"	"66.3"	"58.4"	"46.7"	"72.4"	"85.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P16278"	"Beta-galactosidase OS=Homo sapiens OX=9606 GN=GLB1 PE=1 SV=2"	"3"	"2"	"3"	"2"	"677"	"76.0"	"6.57"	"613.77"	"2.81"	"2"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01301, Pf13364"	"2720"	"ENSG00000170266"	"GLB1"	"B2R7H8; B7Z6B0; hsa:2720; P16278; P16279"	"Ectoderm differentiation; Degradation pathway of sphingolipids, including diseases; Ciliary landscape; Glycosaminoglycan degradation; Sphingolipid metabolism in senescence"	"Neutrophil degranulation; Glycosphingolipid metabolism; HS-GAG degradation; Sialic acid metabolism; Keratan sulfate degradation; Defective NEU1 causes sialidosis; MPS IV - Morquio syndrome B"	"12"	"0"	"23.5"	"18.5"	"14.8"	"14.6"	"19.8"	"16.8"	"21.0"	"23.8"	"18.3"	"26.5"	"33.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WUB8"	"PHD finger protein 10 OS=Homo sapiens OX=9606 GN=PHF10 PE=1 SV=3"	"2"	"1"	"2"	"1"	"498"	"56.0"	"6.62"	"337.78"	"2.81"	"1"	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00628"	"55274"	"ENSG00000130024"	"PHF10"	"hsa:55274; Q2YDA3; Q53HG8; Q8WUB8; Q9BXD2; Q9NV26"	""	""	"0"	"0"	"16.0"	"5.7"	"6.2"	"12.9"	"10.6"	"13.1"	"19.8"	"19.3"	"9.2"	"18.5"	"28.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13155"	"Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 OS=Homo sapiens OX=9606 GN=AIMP2 PE=1 SV=2"	"4"	"1"	"2"	"1"	"320"	"35.3"	"8.22"	"315.48"	"2.80"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf14497, Pf16780, Pf18569"	"7965"	"ENSG00000106305"	"AIMP2"	"F8W950; hsa:7965; Q13155; Q75MR1; Q96CZ5; Q9P1L2"	"Osteoclast signaling; Transcriptional activation by NRF2 in response to phytochemicals; NRF2-ARE regulation"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IVL6"	"Prolyl 3-hydroxylase 3 OS=Homo sapiens OX=9606 GN=P3H3 PE=1 SV=1"	"3"	"1"	"2"	"1"	"736"	"81.8"	"6.32"	"272.62"	"2.80"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf13640"	"10536"	"ENSG00000110811"	"P3H3"	"hsa:10536; Q13512; Q15740; Q66K32; Q6NX61; Q7L2T1; Q8IVL6"	""	"Collagen biosynthesis and modifying enzymes"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00193"	"Small acidic protein OS=Homo sapiens OX=9606 GN=SMAP PE=1 SV=1"	"4"	"1"	"2"	"1"	"183"	"20.3"	"4.72"	"243.39"	"2.80"	"1"	"1"	""	""	""	"Pf15477"	"10944"	"ENSG00000110696"	"SMAP"	"B2RD28; hsa:10944; O00193"	""	""	"0"	"0"	"149.4"	"77.7"	"110.9"	"118.8"	"129.4"	"546.4"	"294.7"	"218.9"	"160.4"	"250.2"	"330.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92796"	"Disks large homolog 3 OS=Homo sapiens OX=9606 GN=DLG3 PE=1 SV=2"	"1"	"1"	"2"	"1"	"817"	"90.3"	"7.03"	"330.47"	"2.80"	"1"	"1"	"cell-cell signaling;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00018, Pf00595, Pf00625, Pf10600"	"1741"	"ENSG00000082458"	"DLG3"	"B4E0H1; D3DVU5; hsa:1741; Q5JUW6; Q5JUW7; Q92796; Q9ULI8"	""	"Assembly and cell surface presentation of NMDA receptors; RAF/MAP kinase cascade; Ras activation upon Ca2+ influx through NMDA receptor; Unblocking of NMDA receptors, glutamate binding and activation; Negative regulation of NMDA receptor-mediated neuronal transmission; Long-term potentiation; Neurexins and neuroligins; Synaptic adhesion-like molecules; NrCAM interactions; Activation of Ca-permeable Kainate Receptor"	"10"	"0"	"15.7"	"10.5"	"11.5"	"10.4"	"11.1"	"15.1"	"19.2"	"19.3"	"22.0"	"24.8"	"28.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRJ7"	"Tudor-interacting repair regulator protein OS=Homo sapiens OX=9606 GN=NUDT16L1 PE=1 SV=1"	"5"	"1"	"2"	"1"	"211"	"23.3"	"8.91"	"347.26"	"2.79"	"1"	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity"	""	"84309"	"ENSG00000168101"	"NUDT16L1"	"hsa:84309; Q8NAI2; Q9BRJ7"	""	""	"0"	"0"	"5.8"	"5.4"	"5.2"	"5.9"	"5.1"	"7.9"	"15.2"	"21.4"	"16.5"	"13.8"	"23.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15014"	"Mortality factor 4-like protein 2 OS=Homo sapiens OX=9606 GN=MORF4L2 PE=1 SV=1"	"3"	"1"	"2"	"1"	"288"	"32.3"	"9.72"	"305.61"	"2.79"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	""	"Pf05712"	"9643"	"ENSG00000123562"	"MORF4L2"	"B3KP92; D3DXA5; hsa:9643; Q15014; Q567V0; Q8J026"	""	"HATs acetylate histones"	"1"	"0"	"45.3"	"24.8"	"42.0"	"45.9"	"41.2"	"44.2"	"117.9"	"109.1"	"88.0"	"133.7"	"191.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09669"	"Cytochrome c oxidase subunit 6C OS=Homo sapiens OX=9606 GN=COX6C PE=1 SV=2"	"11"	"1"	"2"	"1"	"75"	"8.8"	"10.39"	"306.55"	"2.79"	"1"	"1"	"other metabolic processes"	"other membranes;mitochondrion"	""	"Pf02937"	"1345"	"ENSG00000164919"	"COX6C"	"B2R4D7; hsa:1345; P09669"	"Electron transport chain: OXPHOS system in mitochondria; Ciliary landscape; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly; 5q35 copy number variation"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"8"	"0"	"384.4"	"220.9"	"179.8"	"110.8"	"193.2"	"257.8"	"296.9"	"158.8"	"104.5"	"352.3"	"408.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75530"	"Polycomb protein EED OS=Homo sapiens OX=9606 GN=EED PE=1 SV=2"	"2"	"1"	"2"	"1"	"441"	"50.2"	"7.03"	"273.75"	"2.79"	"1"	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00400"	"8726"	"ENSG00000074266"	"EED"	"A8K7V5; hsa:8726; O00149; O75530; Q6NTH2; Q7LDA5; Q7LDG8; Q86VV2; Q9UNY7"	"Histone modifications; Interactome of polycomb repressive complex 2 (PRC2) ; Tumor suppressor activity of SMARCB1; Epithelial to mesenchymal transition in colorectal cancer; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; Pleural mesothelioma; 5q35 copy number variation"	"HCMV Early Events; Oxidative Stress Induced Senescence; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6; Activation of anterior HOX genes in hindbrain development during early embryogenesis; PKMTs methylate histone lysines; PRC2 methylates histones and DNA; Defective pyroptosis"	"15"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96JB5"	"CDK5 regulatory subunit-associated protein 3 OS=Homo sapiens OX=9606 GN=CDK5RAP3 PE=1 SV=2"	"3"	"2"	"3"	"1"	"506"	"56.9"	"4.75"	"483.35"	"2.79"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf05600"	"80279"	"ENSG00000108465"	"CDK5RAP3"	"B7Z6N4; D3DTU1; D3DTU2; F5H3I5; hsa:80279; Q53FA2; Q96JB5; Q9H3F8; Q9H8G0; Q9HBR9"	""	""	"0"	"0"	"14.4"	"11.2"	"15.3"	"13.6"	"12.8"	"18.0"	"34.5"	"30.3"	"26.8"	"40.7"	"52.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99426"	"Tubulin-folding cofactor B OS=Homo sapiens OX=9606 GN=TBCB PE=1 SV=2"	"3"	"1"	"2"	"1"	"244"	"27.3"	"5.15"	"335.97"	"2.79"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf01302, Pf14560"	"1155"	"ENSG00000105254"	"TBCB"	"hsa:1155; O00111; O00674; O14728; Q6FGY5; Q99426"	""	"Post-chaperonin tubulin folding pathway"	"1"	"0"	"87.2"	"56.4"	"81.5"	"71.1"	"70.0"	"77.5"	"102.7"	"94.4"	"69.7"	"110.8"	"181.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A6NED2"	"RCC1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RCCD1 PE=1 SV=1"	"3"	"1"	"2"	"1"	"376"	"40.1"	"5.27"	"275.81"	"2.78"	"1"	"1"	"cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf00415"	"91433"	"ENSG00000166965"	"RCCD1"	"A6NED2; B2RTP9; hsa:91433; Q29RX6"	""	""	"0"	"0"	"32.4"	"30.2"	"34.3"	"37.2"	"39.2"	"43.8"	"63.7"	"58.2"	"46.9"	"72.6"	"106.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14676"	"Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3"	"0"	"1"	"2"	"1"	"2089"	"226.5"	"5.47"	"259.55"	"2.78"	"1"	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	""	"Pf00498, Pf16770"	"9656"	"ENSG00000137337; ENSG00000206481; ENSG00000224587; ENSG00000225589; ENSG00000228575; ENSG00000231135; ENSG00000234012; ENSG00000237095"	"MDC1"	"A2AB04; A2BF04; A2RRA8; A7YY86; B0S8A2; hsa:9656; Q0EFC2; Q14676; Q2L6H7; Q2TAZ4; Q5JP55; Q5JP56; Q5ST83; Q68CQ3; Q86Z06; Q96QC2"	"ATM signaling in development and disease ; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; NIPBL role in DNA damage - Cornelia de Lange syndrome"	"TP53 Regulates Transcription of DNA Repair Genes; SUMOylation of DNA damage response and repair proteins; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; Nonhomologous End-Joining (NHEJ)"	"9"	"0"	"43.6"	"42.0"	"51.3"	"43.8"	"40.1"	"51.3"	"74.8"	"73.2"	"68.9"	"99.4"	"137.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14908"	"PDZ domain-containing protein GIPC1 OS=Homo sapiens OX=9606 GN=GIPC1 PE=1 SV=2"	"4"	"1"	"2"	"1"	"333"	"36.0"	"6.28"	"368.03"	"2.78"	"1"	"1"	"cell-cell signaling;transport;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00595"	"10755"	"ENSG00000123159"	"GIPC1"	"A8K4I3; A8MZG3; hsa:10755; O14908; Q9BTC9"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50454"	"Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2"	"5"	"1"	"1"	"1"	"418"	"46.4"	"8.69"	""	"2.76"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;other membranes;ER/Golgi"	"enzyme regulator activity;other molecular function"	"Pf00079"	"871"	"ENSG00000149257"	"SERPINH1"	"B3KVJ3; hsa:871; P29043; P50454; Q5XPB4; Q6NSJ6; Q8IY96; Q9NP88"	"Endochondral ossification; Type I collagen synthesis in the context of osteogenesis imperfecta; Endochondral ossification with skeletal dysplasias; 15q13.3 copy number variation syndrome; 15q11q13 copy number variation"	"Collagen biosynthesis and modifying enzymes"	"6"	"0"	"3.8"	"5.2"	"4.5"	"7.5"	"8.7"	"7.7"	"19.1"	"10.7"	"8.9"	"18.1"	"25.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UPQ3"	"Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=AGAP1 PE=1 SV=4"	"2"	"1"	"1"	"1"	"857"	"94.4"	"7.94"	""	"2.76"	""	"1"	"transport;other biological processes"	"other cell component"	"enzyme regulator activity;other molecular function"	"Pf00071, Pf01412, Pf12796"	"116987"	"ENSG00000157985"	"AGAP1"	"B2RTX7; hsa:116987; Q541S5; Q6P9D7; Q9NV93; Q9UPQ3"	"2q37 copy number variation syndrome"	""	"1"	"0"	"0.0"	"6.5"	"7.0"	"3.4"	"4.3"	"7.6"	"17.9"	"21.8"	"20.1"	"40.8"	"54.6"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BR76"	"Coronin-1B OS=Homo sapiens OX=9606 GN=CORO1B PE=1 SV=1"	"2"	"1"	"2"	"1"	"489"	"54.2"	"5.88"	"346.17"	"2.76"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf08953, Pf16300"	"57175"	"ENSG00000172725"	"CORO1B"	"B2RD45; hsa:57175; Q9BR76"	""	""	"0"	"0"	"26.3"	"13.5"	"26.0"	"25.7"	"29.0"	"27.2"	"54.5"	"60.3"	"39.7"	"65.0"	"98.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12846"	"Syntaxin-4 OS=Homo sapiens OX=9606 GN=STX4 PE=1 SV=2"	"4"	"1"	"2"	"1"	"297"	"34.2"	"6.28"	"248.28"	"2.76"	"1"	"1"	"cell organization and biogenesis;stress response;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00804, Pf05739"	"6810"	"ENSG00000103496"	"STX4"	"A8MXY0; hsa:6810; Q12846; Q15525; Q6FHE8"	"Insulin signaling"	"ER-Phagosome pathway; Translocation of SLC2A4 (GLUT4) to the plasma membrane; trans-Golgi Network Vesicle Budding; Disinhibition of SNARE formation; Other interleukin signaling"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UJS0"	"Calcium-binding mitochondrial carrier protein Aralar2 OS=Homo sapiens OX=9606 GN=SLC25A13 PE=1 SV=2"	"4"	"2"	"3"	"2"	"675"	"74.1"	"8.62"	"472.98"	"2.76"	"2"	"1"	"other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00153"	"10165"	"ENSG00000004864"	"SLC25A13"	"hsa:10165; O14566; O14575; Q546F9; Q9NZW1; Q9UJS0; Q9UNI7"	""	"Mitochondrial protein import; Gluconeogenesis; Aspartate and asparagine metabolism"	"3"	"0"	"29.8"	"18.9"	"29.7"	"27.6"	"33.1"	"30.7"	"59.8"	"45.1"	"34.3"	"64.4"	"75.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92995"	"Ubiquitin carboxyl-terminal hydrolase 13 OS=Homo sapiens OX=9606 GN=USP13 PE=1 SV=2"	"2"	"1"	"2"	"1"	"863"	"97.3"	"5.53"	"255.48"	"2.75"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00443, Pf00627, Pf02148, Pf17807"	"8975"	"ENSG00000058056"	"USP13"	"A8K2S3; B4DYF3; D3DNS2; hsa:8975; Q92995; Q96B25"	""	"Ub-specific processing proteases; Regulation of PTEN stability and activity"	"2"	"0"	"19.2"	"15.0"	"19.6"	"22.3"	"28.8"	"26.0"	"38.1"	"38.3"	"27.8"	"52.9"	"69.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NX58"	"Cell growth-regulating nucleolar protein OS=Homo sapiens OX=9606 GN=LYAR PE=1 SV=2"	"2"	"1"	"2"	"1"	"379"	"43.6"	"9.54"	"311.45"	"2.75"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"128.1"	"86.4"	"88.1"	"96.9"	"104.7"	"131.8"	"332.8"	"290.4"	"168.5"	"368.1"	"550.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P0U3"	"Sentrin-specific protease 1 OS=Homo sapiens OX=9606 GN=SENP1 PE=1 SV=2"	"3"	"1"	"2"	"1"	"644"	"73.4"	"8.47"	"251.00"	"2.75"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf02902"	"29843"	"ENSG00000079387"	"SENP1"	"A8K7P5; hsa:29843; Q86XC8; Q9P0U3"	""	"SUMO is proteolytically processed; RHOF GTPase cycle"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P17096"	"High mobility group protein HMG-I/HMG-Y OS=Homo sapiens OX=9606 GN=HMGA1 PE=1 SV=3"	"22"	"2"	"3"	"2"	"107"	"11.7"	"10.32"	"999.41"	"2.74"	"2"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	""	"3159"	"ENSG00000137309"	"HMGA1"	"hsa:3159; P10910; P17096; Q5T6U9; Q9UKB0"	"Adipogenesis; Pre-implantation embryo; Male infertility; 7q11.23 copy number variation syndrome; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Orexin receptor pathway"	"Vpr-mediated nuclear import of PICs; 2-LTR circle formation; Integration of viral DNA into host genomic DNA; Autointegration results in viral DNA circles; APOBEC3G mediated resistance to HIV-1 infection; Formation of Senescence-Associated Heterochromatin Foci (SAHF)"	"13"	"0"	"196.2"	"113.9"	"160.8"	"139.1"	"158.1"	"153.4"	"657.9"	"615.9"	"407.3"	"706.2"	"1111.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13616"	"Cullin-1 OS=Homo sapiens OX=9606 GN=CUL1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"776"	"89.6"	"8.00"	"261.06"	"2.74"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00888, Pf10557"	"8454"	"ENSG00000055130"	"CUL1"	"D3DWG3; hsa:8454; O60719; Q08AL6; Q13616; Q8IYW1"	"Cell cycle; TNF-alpha signaling pathway; Parkin-ubiquitin proteasomal system pathway; Apoptosis-related network due to altered Notch3 in ovarian cancer; Glucocorticoid receptor pathway; Nuclear receptors meta-pathway; Pleural mesothelioma; Notch signaling pathway"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; SCF-beta-TrCP mediated degradation of Emi1; Degradation of beta-catenin by the destruction complex; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; NIK-->noncanonical NF-kB signaling; Orc1 removal from chromatin; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Neddylation; SCF(Skp2)-mediated degradation of p27/p21; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Regulation of PLK1 Activity at G2/M Transition; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Circadian Clock; Cyclin D associated events in G1; Regulation of BACH1 activity; MAP3K8 (TPL2)-dependent MAPK1/3 activation; NOTCH1 Intracellular Domain Regulates Transcription; Prolactin receptor signaling; Iron uptake and transport; Nuclear events stimulated by ALK signaling in cancer; Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling"	"40"	"0"	"61.4"	"49.8"	"58.0"	"68.7"	"77.8"	"76.1"	"160.8"	"169.7"	"150.3"	"236.7"	"281.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35658"	"Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2"	"1"	"1"	"2"	"1"	"2090"	"213.5"	"7.47"	"282.39"	"2.74"	"1"	"1"	"cell cycle OR cell proliferation;other metabolic processes;transport;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf18617"	"8021"	"ENSG00000126883"	"NUP214"	"A6NFQ0; hsa:8021; P35658; Q15010; Q3KQZ0; Q5JUP7; Q75R47; Q86XD3"	""	"HCMV Early Events; Rev-mediated nuclear export of HIV RNA; Nuclear import of Rev protein; HCMV Late Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; HuR (ELAVL1) binds and stabilizes mRNA"	"29"	"0"	"14.8"	"7.3"	"14.1"	"12.1"	"8.7"	"11.6"	"18.7"	"17.4"	"13.9"	"18.4"	"35.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23378"	"Glycine dehydrogenase (decarboxylating), mitochondrial OS=Homo sapiens OX=9606 GN=GLDC PE=1 SV=2"	"1"	"1"	"2"	"1"	"1020"	"112.7"	"7.11"	"245.18"	"2.74"	"1"	"1"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01212, Pf02347"	"2731"	"ENSG00000178445"	"GLDC"	"hsa:2731; P23378; Q2M2F8"	"Metabolic Epileptic Disorders"	"Glycine degradation"	"2"	"0"	"11.2"	"8.1"	"14.6"	"14.5"	"14.6"	"19.0"	"24.0"	"29.1"	"23.2"	"49.4"	"75.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T7N3"	"KN motif and ankyrin repeat domain-containing protein 4 OS=Homo sapiens OX=9606 GN=KANK4 PE=1 SV=1"	"1"	"1"	"1"	"1"	"995"	"107.3"	"5.27"	""	"2.73"	""	"1"	"cell organization and biogenesis"	"cytosol;cytoskeleton;other cell component"	""	"Pf00023, Pf12075, Pf13857"	"163782"	"ENSG00000132854"	"KANK4"	"B1ALP7; hsa:163782; Q5T7N3; Q6P9A0; Q86T71; Q86VE6; Q8NAX3"	""	""	"0"	"0"	"61.1"	"50.3"	"68.6"	"67.4"	"76.4"	"72.4"	"170.6"	"137.3"	"78.6"	"154.3"	"234.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05023"	"Sodium/potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1023"	"112.8"	"5.49"	"285.25"	"2.73"	"1"	"1"	"transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cell component"	"transporter activity;other molecular function"	"Pf00122, Pf00689, Pf00690, Pf13246"	"476"	"ENSG00000163399"	"ATP1A1"	"B2RBR6; B7Z2T5; B7Z3U6; F5H3A1; hsa:476; P05023; Q16689; Q6LDM4; Q9UCN1; Q9UJ20; Q9UJ21"	"Pre-implantation embryo; Proximal tubule transport; Arsenic metabolism and reactive oxygen species generation"	"Potential therapeutics for SARS; Ion homeostasis; Ion transport by P-type ATPases"	"6"	"0"	"15.4"	"14.5"	"14.3"	"11.1"	"15.3"	"16.9"	"17.4"	"20.1"	"14.2"	"29.2"	"32.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NZQ3"	"NCK-interacting protein with SH3 domain OS=Homo sapiens OX=9606 GN=NCKIPSD PE=1 SV=1"	"2"	"1"	"2"	"1"	"722"	"78.9"	"6.38"	"259.44"	"2.73"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;cytoskeleton;nucleus"	"cytoskeletal activity;other molecular function"	"Pf00018, Pf09431"	"51517"	"ENSG00000213672"	"NCKIPSD"	"B4DFL5; hsa:51517; Q6GU34; Q6SPF3; Q8TC10; Q9NZQ3; Q9UGM8"	""	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L804"	"Rab11 family-interacting protein 2 OS=Homo sapiens OX=9606 GN=RAB11FIP2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"512"	"58.2"	"9.32"	"369.34"	"2.72"	"1"	"1"	"cell-cell signaling;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00168, Pf09457"	"22841"	"ENSG00000107560"	"RAB11FIP2"	"A6NEI4; hsa:22841; Q3I768; Q7L804; Q9Y2F0"	""	"Vasopressin regulates renal water homeostasis via Aquaporins"	"1"	"0"	"28.1"	"15.4"	"26.8"	"25.4"	"33.8"	"27.1"	"103.6"	"211.6"	"206.9"	"318.9"	"380.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60911"	"Cathepsin L2 OS=Homo sapiens OX=9606 GN=CTSV PE=1 SV=2"	"4"	"1"	"2"	"1"	"334"	"37.3"	"8.76"	"355.54"	"2.72"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;other cytoplasmic organelle"	"enzyme regulator activity;other molecular function"	"Pf00112, Pf08246"	"1515"	"ENSG00000136943"	"CTSV"	"hsa:1515; O60233; O60911; Q2TB86; Q5T1U0"	"Endochondral ossification; Endochondral ossification with skeletal dysplasias; Pancreatic cancer subtypes"	"MHC class II antigen presentation; Assembly of collagen fibrils and other multimeric structures; RUNX1 regulates transcription of genes involved in differentiation of keratinocytes; Trafficking and processing of endosomal TLR; Endosomal/Vacuolar pathway; Activation of Matrix Metalloproteinases"	"10"	"0"	"9.8"	"3.2"	"10.1"	"7.0"	"7.3"	"11.0"	"41.6"	"41.0"	"34.5"	"57.7"	"93.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNM6"	"26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2"	"2"	"1"	"2"	"1"	"376"	"42.9"	"5.81"	"345.44"	"2.72"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf01399"	"5719"	"ENSG00000185627"	"PSMD13"	"B3KT15; hsa:5719; O75831; Q53XU2; Q9UNM6; Q9UNV3"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"Antigen processing: Ubiquitination & Proteasome degradation; FCERI mediated NF-kB activation; Downstream TCR signaling; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"65"	"0"	"110.2"	"66.3"	"122.3"	"93.5"	"97.6"	"119.6"	"145.4"	"141.8"	"126.1"	"207.5"	"289.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UJ83"	"2-hydroxyacyl-CoA lyase 1 OS=Homo sapiens OX=9606 GN=HACL1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"578"	"63.7"	"7.36"	"294.54"	"2.72"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00205, Pf02775, Pf02776"	"26061"	"ENSG00000131373"	"HACL1"	"B4DWI1; B4DXI5; E9PEN4; hsa:26061; Q9BV42; Q9P0A2; Q9UJ83"	""	"Peroxisomal protein import; Alpha-oxidation of phytanate"	"2"	"0"	"23.5"	"18.2"	"22.2"	"26.0"	"26.8"	"35.8"	"63.2"	"58.5"	"55.5"	"103.7"	"190.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H7N4"	"Splicing factor, arginine/serine-rich 19 OS=Homo sapiens OX=9606 GN=SCAF1 PE=1 SV=3"	"1"	"1"	"2"	"1"	"1312"	"139.2"	"9.25"	"270.93"	"2.72"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	""	"58506"	"ENSG00000126461"	"SCAF1"	"hsa:58506; Q7Z5V7; Q8WVA1; Q9H7N4; Q9NR59"	""	""	"0"	"0"	"17.6"	"11.8"	"15.0"	"15.0"	"16.9"	"20.0"	"37.9"	"28.5"	"21.0"	"40.8"	"39.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q53H96"	"Pyrroline-5-carboxylate reductase 3 OS=Homo sapiens OX=9606 GN=PYCR3 PE=1 SV=3"	"5"	"1"	"2"	"1"	"274"	"28.6"	"7.72"	"297.02"	"2.71"	"1"	"1"	"other metabolic processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf03807, Pf14748"	"65263"	"ENSG00000104524; ENSG00000276657"	"PYCR3"	"B3KMB5; B4DVT6; H0Y6C3; hsa:65263; Q53H96; Q8N3N9; Q96HX4; Q9H896"	""	"Glutamate and glutamine metabolism"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y223"	"Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase OS=Homo sapiens OX=9606 GN=GNE PE=1 SV=1"	"2"	"1"	"2"	"1"	"722"	"79.2"	"6.80"	"310.64"	"2.71"	"1"	"1"	"cell adhesion;other metabolic processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00480, Pf02350"	"10020"	"ENSG00000159921"	"GNE"	"A6PZH2; A6PZH3; A7UNU7; B2R6E1; B7Z372; B7Z428; D3DRP7; F5H499; H0YFA7; hsa:10020; Q0VA94; Q9Y223"	""	"Sialic acid metabolism; Defective GNE causes sialuria, NK and IBM2"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H1E3"	"Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 OS=Homo sapiens OX=9606 GN=NUCKS1 PE=1 SV=1"	"4"	"1"	"2"	"1"	"243"	"27.3"	"5.08"	"301.04"	"2.70"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	""	"64710"	"ENSG00000069275"	"NUCKS1"	"hsa:64710; Q54AC0; Q5PXE7; Q9H1D6; Q9H1E3; Q9H723"	""	""	"0"	"0"	"73.0"	"44.6"	"61.6"	"60.2"	"73.0"	"70.3"	"190.4"	"156.6"	"110.0"	"162.3"	"201.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61006"	"Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1"	"9"	"2"	"3"	"2"	"207"	"23.7"	"9.07"	"690.31"	"2.70"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00071"	"4218"	"ENSG00000167461"	"RAB8A"	"B4DEK7; hsa:4218; P24407; P61006; Q6FHV5"	"Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Ciliary landscape; Joubert syndrome"	"Regulation of PLK1 Activity at G2/M Transition; Anchoring of the basal body to the plasma membrane; RAB geranylgeranylation; TBC/RABGAPs; RAB GEFs exchange GTP for GDP on RABs; Translocation of SLC2A4 (GLUT4) to the plasma membrane; VxPx cargo-targeting to cilium"	"10"	"0"	"169.7"	"118.3"	"141.9"	"99.0"	"141.1"	"147.3"	"204.8"	"165.7"	"125.7"	"246.6"	"333.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5Z4"	"Heme-binding protein 2 OS=Homo sapiens OX=9606 GN=HEBP2 PE=1 SV=1"	"6"	"1"	"2"	"1"	"205"	"22.9"	"4.63"	"273.20"	"2.70"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"non-structural extracellular;mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf04832"	"23593"	"ENSG00000051620"	"HEBP2"	"hsa:23593; Q96P57; Q9Y5Z4"	""	"Neutrophil degranulation"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51665"	"26S proteasome non-ATPase regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMD7 PE=1 SV=2"	"3"	"1"	"2"	"1"	"324"	"37.0"	"6.77"	"267.60"	"2.69"	"1"	"1"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf01398, Pf13012"	"5713"	"ENSG00000103035"	"PSMD7"	"D3DWS9; hsa:5713; P51665; Q6PKI2; Q96E97"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Neutrophil degranulation; Regulation of expression of SLITs and ROBOs; Degradation of GLI1 by the proteasome; Hedgehog 'on' state; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"65"	"0"	"14.0"	"5.9"	"13.8"	"14.0"	"14.7"	"11.4"	"18.9"	"17.5"	"13.9"	"26.2"	"35.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P29144"	"Tripeptidyl-peptidase 2 OS=Homo sapiens OX=9606 GN=TPP2 PE=1 SV=4"	"1"	"1"	"2"	"1"	"1249"	"138.3"	"6.32"	"286.76"	"2.68"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00082, Pf12580"	"7174"	"ENSG00000134900"	"TPP2"	"hsa:7174; P29144; Q5VZU8"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00233"	"26S proteasome non-ATPase regulatory subunit 9 OS=Homo sapiens OX=9606 GN=PSMD9 PE=1 SV=3"	"4"	"1"	"2"	"1"	"223"	"24.7"	"6.95"	"331.07"	"2.68"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf02163, Pf17820, Pf18265"	"5715"	"ENSG00000110801"	"PSMD9"	"B2RD35; G3V1Q6; hsa:5715; O00233; Q9BQ42"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"63"	"0"	"59.5"	"39.3"	"44.4"	"54.2"	"43.2"	"60.6"	"86.6"	"83.5"	"68.5"	"95.2"	"120.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NB78"	"Lysine-specific histone demethylase 1B OS=Homo sapiens OX=9606 GN=KDM1B PE=1 SV=3"	"1"	"1"	"2"	"1"	"822"	"92.0"	"7.87"	"258.62"	"2.68"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf01593, Pf04433, Pf07496"	"221656"	"ENSG00000165097"	"KDM1B"	"A2A2C5; A2A2C6; hsa:221656; Q5TGV3; Q6AI15; Q6ZUU4; Q8N258; Q8NB78; Q96EL7"	"Vitamin D-sensitive calcium signaling in depression"	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux; UCH proteinases; HDMs demethylate histones"	"4"	"0"	"4.8"	"6.1"	"5.4"	"3.2"	"12.2"	"9.0"	"13.1"	"12.1"	"10.1"	"18.7"	"22.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14919"	"Dr1-associated corepressor OS=Homo sapiens OX=9606 GN=DRAP1 PE=1 SV=3"	"5"	"1"	"2"	"1"	"205"	"22.3"	"5.17"	"294.41"	"2.67"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00808"	"10589"	"ENSG00000175550"	"DRAP1"	"hsa:10589; Q13448; Q14919"	""	"Signaling by NODAL; Signaling by Activin"	"2"	"0"	"28.6"	"20.8"	"24.3"	"30.5"	"31.3"	"38.4"	"61.8"	"43.0"	"37.4"	"60.6"	"74.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UGJ0"	"5'-AMP-activated protein kinase subunit gamma-2 OS=Homo sapiens OX=9606 GN=PRKAG2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"569"	"63.0"	"9.35"	"348.79"	"2.67"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00571"	"51422"	"ENSG00000106617"	"PRKAG2"	"hsa:51422; Q53Y07; Q6NUI0; Q75MP4; Q9NUZ9; Q9UDN8; Q9UGJ0; Q9ULX8"	"AMP-activated protein kinase signaling; Target of rapamycin signaling; Energy metabolism; Sterol regulatory element-binding proteins (SREBP) signaling; Ectoderm differentiation; Angiopoietin-like protein 8 regulatory pathway; Lipid metabolism pathway; Thermogenesis; Nonalcoholic fatty liver disease; Synaptic signaling pathways associated with autism spectrum disorder; Hippo signaling regulation pathways; 1q21.1 copy number variation syndrome; Autophagy; p53 transcriptional gene network; Pleural mesothelioma"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; TP53 Regulates Metabolic Genes; Activation of AMPK downstream of NMDARs; Regulation of TP53 Activity through Phosphorylation; Carnitine metabolism; Macroautophagy; Energy dependent regulation of mTOR by LKB1-AMPK; AMPK inhibits chREBP transcriptional activation activity; Activation of PPARGC1A (PGC-1alpha) by phosphorylation; Lipophagy"	"25"	"0"	"34.4"	"20.7"	"40.6"	"37.3"	"38.4"	"37.2"	"79.1"	"72.0"	"46.9"	"78.4"	"128.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43674"	"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFB5 PE=1 SV=1"	"6"	"1"	"2"	"1"	"189"	"21.7"	"9.63"	"241.21"	"2.67"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion;nucleus"	"transporter activity"	"Pf09781"	"4711"	"ENSG00000136521"	"NDUFB5"	"hsa:4711; O43674; Q561V6"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"8.9"	"6.3"	"11.7"	"7.7"	"10.5"	"8.5"	"11.1"	"10.8"	"2.8"	"12.9"	"22.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12899"	"Tripartite motif-containing protein 26 OS=Homo sapiens OX=9606 GN=TRIM26 PE=1 SV=1"	"2"	"1"	"2"	"1"	"539"	"62.1"	"5.03"	"239.37"	"2.67"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00622, Pf00643, Pf13765, Pf15227"	"7726"	"ENSG00000137313; ENSG00000226060; ENSG00000228881; ENSG00000230230; ENSG00000231002; ENSG00000231641; ENSG00000234046; ENSG00000234127"	"TRIM26"	"A6NG96; hsa:7726; Q12899; Q5SRL2"	""	"Interferon gamma signaling"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94760"	"N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 OS=Homo sapiens OX=9606 GN=DDAH1 PE=1 SV=3"	"3"	"1"	"2"	"1"	"285"	"31.1"	"5.81"	"343.63"	"2.66"	"1"	"1"	"other metabolic processes;signal transduction;other biological processes"	"cytosol"	"other molecular function"	"Pf02274"	"23576"	"ENSG00000153904"	"DDAH1"	"hsa:23576; O94760; Q5HYC8; Q86XK5"	"Mesodermal commitment pathway; Nitric oxide metabolism in cystic fibrosis"	"eNOS activation"	"3"	"0"	"34.0"	"28.8"	"37.1"	"20.1"	"28.1"	"37.0"	"46.1"	"37.3"	"27.6"	"48.7"	"70.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96FK6"	"WD repeat-containing protein 89 OS=Homo sapiens OX=9606 GN=WDR89 PE=2 SV=1"	"3"	"1"	"2"	"1"	"387"	"43.2"	"6.13"	"293.30"	"2.66"	"1"	"1"	"developmental processes"	""	""	"Pf00400"	"112840"	"ENSG00000140006"	"WDR89"	"hsa:112840; Q96FK6"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14254"	"Flotillin-2 OS=Homo sapiens OX=9606 GN=FLOT2 PE=1 SV=2"	"3"	"1"	"2"	"1"	"428"	"47.0"	"5.25"	"445.84"	"2.65"	"1"	"1"	"cell adhesion;transport;other biological processes"	"plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	""	"Pf01145"	"2319"	"ENSG00000132589"	"FLOT2"	"hsa:2319; Q14254"	"Angiopoietin-like protein 8 regulatory pathway; Insulin signaling"	"Regulation of necroptotic cell death; RND1 GTPase cycle; RND3 GTPase cycle; RHOC GTPase cycle; RHOA GTPase cycle; RHOB GTPase cycle; Synaptic adhesion-like molecules"	"10"	"0"	"73.3"	"42.2"	"41.2"	"30.9"	"48.4"	"45.4"	"53.0"	"53.2"	"36.2"	"77.9"	"79.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95391"	"Pre-mRNA-splicing factor SLU7 OS=Homo sapiens OX=9606 GN=SLU7 PE=1 SV=2"	"2"	"1"	"1"	"1"	"586"	"68.3"	"7.14"	""	"2.65"	""	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;transport"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf11708"	"10569"	"ENSG00000164609"	"SLU7"	"D3DQK2; hsa:10569; O95391; Q3LUJ0; Q3LUJ1; Q6RXQ5; Q96FM9"	""	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"4"	"0"	"12.8"	"6.0"	"6.8"	"15.8"	"10.9"	"14.9"	"19.8"	"26.6"	"22.4"	"35.6"	"32.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A3KMH1"	"von Willebrand factor A domain-containing protein 8 OS=Homo sapiens OX=9606 GN=VWA8 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1905"	"214.7"	"7.40"	"346.35"	"2.65"	"1"	"1"	""	"mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf07728"	"23078"	"ENSG00000102763"	"VWA8"	"A3KMH1; hsa:23078; O60310; Q5JTP6; Q5VW08; Q7Z6I9; Q86YC9; Q8N3E4"	""	""	"0"	"0"	"13.7"	"17.1"	"22.8"	"20.6"	"20.8"	"26.0"	"64.8"	"63.3"	"55.4"	"70.7"	"75.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35226"	"Polycomb complex protein BMI-1 OS=Homo sapiens OX=9606 GN=BMI1 PE=1 SV=2"	"7"	"3"	"4"	"3"	"326"	"36.9"	"8.63"	"770.40"	"2.65"	"3"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf13923, Pf16207"	"100532731; 648"	"ENSG00000168283"	"BMI1"	"hsa:100532731; hsa:648; P35226; Q16030; Q5T8Z3; Q96F37"	"Pleural mesothelioma; Interactions of natural killer cells in pancreatic cancer; CCL18 signaling pathway"	"SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Oxidative Stress Induced Senescence; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6"	"12"	"0"	"184.9"	"104.1"	"142.4"	"186.9"	"164.0"	"211.5"	"400.4"	"378.1"	"239.1"	"378.7"	"532.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H9J2"	"39S ribosomal protein L44, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL44 PE=1 SV=1"	"2"	"1"	"2"	"1"	"332"	"37.5"	"8.40"	"339.70"	"2.65"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"plasma membrane;other membranes;mitochondrion;translational apparatus;nucleus"	"nucleic acid binding activity;other molecular function"	""	"65080"	"ENSG00000135900"	"MRPL44"	"hsa:65080; Q53S16; Q6IA62; Q9H821; Q9H9J2"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"156.2"	"87.5"	"124.6"	"124.9"	"124.6"	"135.4"	"233.8"	"212.1"	"140.9"	"266.1"	"402.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BVJ6"	"U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1"	"3"	"2"	"3"	"2"	"771"	"87.9"	"7.87"	"508.88"	"2.64"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf04615"	"10813"	"ENSG00000156697"	"UTP14A"	"A8K7A3; A8MVQ1; B4DQ08; E9PEL7; hsa:10813; Q5JYF1; Q9BVJ6"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"9.1"	"5.0"	"7.1"	"6.0"	"5.0"	"4.4"	"19.2"	"17.4"	"14.2"	"19.4"	"39.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31944"	"Caspase-14 OS=Homo sapiens OX=9606 GN=CASP14 PE=1 SV=2"	"4"	"1"	"2"	"1"	"242"	"27.7"	"5.58"	"366.12"	"2.64"	"1"	"1"	"protein metabolism;other biological processes"	"plasma membrane;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00656"	"23581"	"ENSG00000105141"	"CASP14"	"hsa:23581; O95823; P31944; Q3SYC9"	"Vitamin D receptor pathway"	"Formation of the cornified envelope"	"2"	"0"	"38.2"	"17.2"	"65.1"	"27.8"	"33.2"	"23.3"	"82.5"	"81.8"	"61.1"	"84.2"	"96.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P21912"	"Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHB PE=1 SV=3"	"3"	"1"	"2"	"1"	"280"	"31.6"	"8.76"	"307.14"	"2.64"	"1"	"1"	"other metabolic processes"	"plasma membrane;other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf13085, Pf13534"	"6390"	"ENSG00000117118"	"SDHB"	"B2R545; hsa:6390; P21912; Q0QEY7; Q9NQ12"	"Electron transport chain: OXPHOS system in mitochondria; Metabolic reprogramming in colon cancer; Nonalcoholic fatty liver disease; Mitochondrial complex II assembly; TCA cycle (aka Krebs or citric acid cycle)"	"Respiratory electron transport; Citric acid cycle (TCA cycle)"	"7"	"0"	"103.6"	"65.6"	"74.7"	"70.5"	"75.3"	"78.1"	"141.8"	"143.6"	"127.6"	"159.5"	"164.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P0DPB5"	"Protein POLR1D, isoform 2 OS=Homo sapiens OX=9606 GN=POLR1D PE=1 SV=1"	"12"	"2"	"3"	"2"	"122"	"14.3"	"9.88"	"544.80"	"2.64"	"2"	"1"	""	"cytosol;nucleus"	""	""	"51082"	"ENSG00000186184"	"POLR1D"	"P0DPB5; Q5TBX2; Q96BR3; Q9Y2S0"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"16"	"0"	"163.8"	"74.0"	"116.5"	"120.7"	"129.3"	"128.8"	"524.6"	"491.6"	"324.0"	"550.5"	"785.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75688"	"Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1"	"2"	"1"	"2"	"1"	"479"	"52.6"	"5.05"	"340.58"	"2.64"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;cytosol;nucleus"	"other molecular function"	"Pf00481, Pf07830"	"5495"	"ENSG00000138032"	"PPM1B"	"hsa:5495; O75688; Q461Q2; Q4J6C1; Q4J6C2; Q658R4; Q96ER6; Q9HAY8"	"MAPK signaling pathway"	"ISG15 antiviral mechanism; ALK mutants bind TKIs; Signaling by ALK fusions and activated point mutants"	"4"	"0"	"44.8"	"27.1"	"32.9"	"41.2"	"35.6"	"46.2"	"65.1"	"52.4"	"42.3"	"53.5"	"79.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NP81"	"Serine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=SARS2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"518"	"58.2"	"8.13"	"290.02"	"2.63"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00587"	"54938"	"ENSG00000104835; ENSG00000283104"	"SARS2"	"A6NHW7; B4DE10; hsa:54938; Q9BVP3; Q9NP81"	""	"Mitochondrial tRNA aminoacylation"	"1"	"0"	"17.8"	"14.7"	"22.5"	"22.0"	"19.7"	"21.0"	"26.1"	"29.9"	"26.6"	"33.1"	"52.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15910"	"Histone-lysine N-methyltransferase EZH2 OS=Homo sapiens OX=9606 GN=EZH2 PE=1 SV=2"	"2"	"1"	"2"	"1"	"746"	"85.3"	"7.02"	"317.16"	"2.62"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00856, Pf11616, Pf18118, Pf18264"	"2146"	"ENSG00000106462"	"EZH2"	"B2RAQ1; B3KS30; B7Z1D6; B7Z7L6; hsa:2146; Q15755; Q15910; Q75MG3; Q92857; Q96FI6"	"Cell differentiation - expanded index; Histone modifications; Endoderm differentiation; Interactome of polycomb repressive complex 2 (PRC2) ; MECP2 and associated Rett syndrome; Tumor suppressor activity of SMARCB1; Epithelial to mesenchymal transition in colorectal cancer; lncRNA in canonical Wnt signaling and colorectal cancer; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; Pleural mesothelioma"	"HCMV Early Events; Oxidative Stress Induced Senescence; Regulation of PTEN gene transcription; Defective pyroptosis; Transcriptional Regulation by E2F6; Activation of anterior HOX genes in hindbrain development during early embryogenesis; PKMTs methylate histone lysines; PRC2 methylates histones and DNA"	"19"	"0"	"7.3"	"4.0"	"6.5"	"7.9"	"7.7"	"10.2"	"16.1"	"18.1"	"11.6"	"16.1"	"23.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09110"	"3-ketoacyl-CoA thiolase, peroxisomal OS=Homo sapiens OX=9606 GN=ACAA1 PE=1 SV=2"	"4"	"1"	"2"	"1"	"424"	"44.3"	"8.44"	"301.43"	"2.62"	"1"	"1"	"other metabolic processes"	"non-structural extracellular;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00108, Pf02803"	"30"	"ENSG00000060971"	"ACAA1"	"G5E935; hsa:30; P09110; Q96CA6"	"PPAR-alpha pathway; Nuclear receptors meta-pathway; Amino acid metabolism; PPAR signaling pathway; Eicosanoid metabolism via cyclooxygenases (COX); Eicosanoid metabolism via lipooxygenases (LOX)"	"Neutrophil degranulation; TYSND1 cleaves peroxisomal proteins; alpha-linolenic acid (ALA) metabolism; Beta-oxidation of very long chain fatty acids"	"11"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UHB9"	"Signal recognition particle subunit SRP68 OS=Homo sapiens OX=9606 GN=SRP68 PE=1 SV=2"	"1"	"1"	"2"	"1"	"627"	"70.7"	"8.56"	"272.47"	"2.62"	"1"	"1"	"transport;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf16969"	"6730"	"ENSG00000167881"	"SRP68"	"B3KUU5; B3KWY7; G3V1U4; hsa:6730; Q8NCJ4; Q8WUK2; Q9UHB9"	""	"SRP-dependent cotranslational protein targeting to membrane"	"1"	"0"	"14.6"	"8.2"	"12.9"	"8.1"	"12.9"	"14.1"	"31.1"	"30.8"	"17.8"	"24.7"	"32.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9GZZ1"	"N-alpha-acetyltransferase 50 OS=Homo sapiens OX=9606 GN=NAA50 PE=1 SV=1"	"8"	"1"	"1"	"1"	"169"	"19.4"	"8.81"	""	"2.61"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00583"	"80218"	"ENSG00000121579"	"NAA50"	"D3DN74; hsa:80218; Q68DQ1; Q9GZZ1"	"Metapathway biotransformation Phase I and II"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86W42"	"THO complex subunit 6 homolog OS=Homo sapiens OX=9606 GN=THOC6 PE=1 SV=1"	"3"	"1"	"3"	"1"	"341"	"37.5"	"7.43"	"596.61"	"2.61"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00400"	"79228"	"ENSG00000131652"	"THOC6"	"B2RA85; hsa:79228; Q86W42; Q8NBR1; Q9BTV9"	""	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"3"	"0"	"215.2"	"119.2"	"168.9"	"176.9"	"216.7"	"214.7"	"430.6"	"393.5"	"309.1"	"473.5"	"547.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12788"	"Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2"	"2"	"1"	"2"	"1"	"808"	"89.0"	"6.90"	"294.74"	"2.61"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00400, Pf08625"	"10607"	"ENSG00000183751"	"TBL3"	"hsa:10607; Q12788; Q59GD6; Q8IVB7; Q96A78"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q4G0A6"	"Probable ubiquitin carboxyl-terminal hydrolase MINDY-4 OS=Homo sapiens OX=9606 GN=MINDY4 PE=1 SV=2"	"1"	"1"	"2"	"1"	"757"	"84.3"	"6.90"	"291.28"	"2.61"	"1"	"1"	"protein metabolism;other metabolic processes"	""	"other molecular function"	"Pf13898"	"84182"	"ENSG00000106125"	"MINDY4"	"hsa:84182; Q4G0A6; Q71AZ7; Q9H6D2"	""	""	"0"	"0"	"2.9"	"3.1"	"3.1"	"3.3"	"3.3"	"4.1"	"8.4"	"10.1"	"17.0"	"40.6"	"35.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P54105"	"Methylosome subunit pICln OS=Homo sapiens OX=9606 GN=CLNS1A PE=1 SV=1"	"5"	"1"	"2"	"1"	"237"	"26.2"	"4.11"	"358.83"	"2.60"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf03517"	"1207"	"ENSG00000074201"	"CLNS1A"	"B2RCS9; hsa:1207; P54105; Q0VDK6; Q9NRD2; Q9NRD3"	""	"snRNP Assembly"	"1"	"0"	"31.4"	"25.4"	"38.0"	"37.1"	"43.2"	"40.6"	"67.5"	"67.9"	"55.2"	"66.0"	"93.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51114"	"Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3"	"4"	"2"	"3"	"1"	"621"	"69.7"	"6.15"	"835.97"	"2.60"	"2"	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf05641, Pf12235, Pf16096, Pf16097, Pf17904, Pf18336"	"8087"	"ENSG00000114416"	"FXR1"	"A8K9B8; hsa:8087; P51114; Q7Z450; Q8N6R8"	"Bile acids synthesis and enterohepatic circulation"	"Signaling by BRAF and RAF1 fusions"	"2"	"0"	"8.9"	"8.9"	"6.7"	"10.7"	"9.0"	"14.3"	"15.5"	"19.0"	"17.2"	"20.0"	"19.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14232"	"Translation initiation factor eIF-2B subunit alpha OS=Homo sapiens OX=9606 GN=EIF2B1 PE=1 SV=1"	"2"	"1"	"2"	"1"	"305"	"33.7"	"7.33"	"308.90"	"2.60"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01008"	"1967"	"ENSG00000111361"	"EIF2B1"	"A6NLY9; B4DGX0; hsa:1967; Q14232; Q3SXP4"	"Translation factors"	"Recycling of eIF2:GDP"	"2"	"0"	"57.5"	"31.1"	"32.1"	"42.4"	"38.1"	"46.6"	"64.9"	"60.4"	"50.9"	"83.1"	"120.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52815"	"39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2"	"7"	"1"	"2"	"1"	"198"	"21.3"	"8.87"	"241.04"	"2.60"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00542, Pf16320"	"6182"	"ENSG00000262814"	"MRPL12"	"hsa:6182; P52815; Q969U0; Q9HCA2; Q9UQJ3"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"18.0"	"8.4"	"9.5"	"12.5"	"15.3"	"19.4"	"26.4"	"22.3"	"17.9"	"30.3"	"27.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96FW1"	"Ubiquitin thioesterase OTUB1 OS=Homo sapiens OX=9606 GN=OTUB1 PE=1 SV=2"	"3"	"1"	"2"	"1"	"271"	"31.3"	"4.94"	"307.82"	"2.60"	"1"	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf10275"	"55611"	"ENSG00000167770"	"OTUB1"	"hsa:55611; Q32Q78; Q96FW1; Q96II3; Q9NXQ4; Q9P0B8"	""	"Ub-specific processing proteases; Ovarian tumor domain proteases"	"2"	"0"	"84.8"	"52.2"	"77.9"	"46.8"	"54.0"	"61.6"	"94.7"	"83.8"	"61.7"	"115.6"	"149.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16851"	"UTP--glucose-1-phosphate uridylyltransferase OS=Homo sapiens OX=9606 GN=UGP2 PE=1 SV=5"	"2"	"1"	"2"	"1"	"508"	"56.9"	"8.15"	"328.91"	"2.60"	"1"	"1"	"other metabolic processes;developmental processes"	"cytosol;other cell component"	"other molecular function"	"Pf01704"	"7360"	"ENSG00000169764"	"UGP2"	"hsa:7360; Q07131; Q0P6K2; Q16851; Q86Y81; Q9BU15"	"Exercise-induced circadian regulation; Glycogen synthesis and degradation; Glucuronidation"	"Glycogen synthesis; Formation of the active cofactor, UDP-glucuronate"	"5"	"0"	"48.2"	"35.5"	"54.1"	"47.0"	"59.3"	"70.9"	"90.1"	"87.4"	"73.1"	"111.1"	"140.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14258"	"E3 ubiquitin/ISG15 ligase TRIM25 OS=Homo sapiens OX=9606 GN=TRIM25 PE=1 SV=2"	"2"	"1"	"1"	"1"	"630"	"70.9"	"8.09"	""	"2.60"	""	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00622, Pf13445, Pf13765"	"7706"	"ENSG00000121060"	"TRIM25"	"hsa:7706; Q14258"	"Novel intracellular components of RIG-I-like receptor pathway; Cytosolic DNA-sensing pathway; SARS-CoV-2 innate immunity evasion and cell-specific immune response; 1p36 copy number variation syndrome"	"SARS-CoV-1 activates/modulates innate immune responses; ISG15 antiviral mechanism; Interferon gamma signaling; SARS-CoV-2 activates/modulates innate and adaptive immune responses; TRAF6 mediated NF-kB activation; NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10; Termination of translesion DNA synthesis; Negative regulators of DDX58/IFIH1 signaling; Ovarian tumor domain proteases; TRAF3-dependent IRF activation pathway; TRAF6 mediated IRF7 activation"	"16"	"0"	"6.3"	"5.2"	"7.8"	"6.0"	"9.6"	"6.7"	"22.4"	"23.3"	"15.8"	"26.0"	"31.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N0Z6"	"Tetratricopeptide repeat protein 5 OS=Homo sapiens OX=9606 GN=TTC5 PE=1 SV=2"	"2"	"1"	"2"	"1"	"440"	"48.9"	"6.48"	"343.34"	"2.59"	"1"	"1"	"DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf16669"	"91875"	"ENSG00000136319"	"TTC5"	"A8MQ18; hsa:91875; Q8N0Z6; Q96HF9"	""	"Regulation of TP53 Activity through Methylation"	"1"	"0"	"61.7"	"36.6"	"62.1"	"70.1"	"57.5"	"73.7"	"117.8"	"125.6"	"82.6"	"115.1"	"135.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BYI3"	"Hyccin OS=Homo sapiens OX=9606 GN=FAM126A PE=1 SV=2"	"2"	"1"	"2"	"1"	"521"	"57.6"	"8.16"	"255.96"	"2.59"	"1"	"1"	"other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf09790"	"84668"	"ENSG00000122591"	"HYCC1"	"A0A024RA06; A4D145; B8ZZJ1; hsa:84668; Q6N010; Q75MR4; Q7LDZ4; Q96MX1; Q96NQ6; Q9BYI3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P1U0"	"DNA-directed RNA polymerase I subunit RPA12 OS=Homo sapiens OX=9606 GN=ZNRD1 PE=1 SV=1"	"6"	"1"	"2"	"1"	"126"	"13.9"	"5.06"	"298.14"	"2.59"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01096"	"30834"	"ENSG00000066379; ENSG00000206502; ENSG00000224859; ENSG00000233795; ENSG00000235176; ENSG00000235443; ENSG00000236808; ENSG00000236949"	"POLR1H"	"hsa:30834; Q9P1U0"	"Pyrimidine metabolism; 2q13 copy number variation syndrome"	"RNA Polymerase I Transcription Initiation; B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"7"	"0"	"68.2"	"45.3"	"51.4"	"73.6"	"53.6"	"85.1"	"128.9"	"237.5"	"230.8"	"574.1"	"859.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55039"	"Developmentally-regulated GTP-binding protein 2 OS=Homo sapiens OX=9606 GN=DRG2 PE=1 SV=1"	"3"	"1"	"2"	"1"	"364"	"40.7"	"8.88"	"239.63"	"2.59"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01926, Pf02824, Pf16897"	"1819"	"ENSG00000108591"	"DRG2"	"B2R8G5; hsa:1819; P55039; Q53Y50; Q9BWB2"	"Smith-Magenis and Potocki-Lupski syndrome copy number variation"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07384"	"Calpain-1 catalytic subunit OS=Homo sapiens OX=9606 GN=CAPN1 PE=1 SV=1"	"2"	"1"	"2"	"1"	"714"	"81.8"	"5.67"	"238.49"	"2.59"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00648, Pf01067, Pf13833"	"823"	"ENSG00000014216"	"CAPN1"	"hsa:823; P07384; Q2TTR0; Q6DHV4"	"Integrin-mediated cell adhesion; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Formation of the cornified envelope; Degradation of the extracellular matrix; Neutrophil degranulation; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"	"7"	"0"	"12.6"	"7.1"	"15.0"	"10.0"	"10.8"	"16.3"	"25.1"	"24.0"	"15.0"	"26.1"	"35.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H4L7"	"SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 OS=Homo sapiens OX=9606 GN=SMARCAD1 PE=1 SV=2"	"2"	"2"	"3"	"2"	"1026"	"117.3"	"5.55"	"579.18"	"2.59"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271"	"56916"	"ENSG00000163104"	"SMARCAD1"	"B7Z799; hsa:56916; Q05D56; Q96SX1; Q9H017; Q9H4L7; Q9H860; Q9NPU9; Q9ULU7"	""	""	"0"	"0"	"122.2"	"70.8"	"93.5"	"94.1"	"87.3"	"123.4"	"202.2"	"189.4"	"171.2"	"189.6"	"262.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BVG4"	"Protein PBDC1 OS=Homo sapiens OX=9606 GN=PBDC1 PE=1 SV=1"	"5"	"1"	"2"	"1"	"233"	"26.0"	"4.79"	"339.26"	"2.59"	"1"	"1"	""	""	""	"Pf04669"	"51260"	"ENSG00000102390"	"PBDC1"	"hsa:51260; Q9BVG4"	""	""	"0"	"0"	"17.4"	"7.6"	"12.0"	"17.0"	"12.2"	"12.4"	"31.3"	"29.3"	"26.7"	"36.1"	"50.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5HYJ3"	"Protein FAM76B OS=Homo sapiens OX=9606 GN=FAM76B PE=1 SV=3"	"3"	"1"	"1"	"1"	"339"	"38.7"	"9.25"	""	"2.58"	""	"1"	""	"nucleus"	""	"Pf16046"	"143684"	"ENSG00000077458"	"FAM76B"	"B2R9C2; hsa:143684; Q5HYJ3; Q6PIU3; Q8TC53"	""	""	"0"	"0"	"6.3"	"3.7"	"6.6"	"6.8"	"6.6"	"6.5"	"23.0"	"30.1"	"25.5"	"39.3"	"46.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L5N1"	"COP9 signalosome complex subunit 6 OS=Homo sapiens OX=9606 GN=COPS6 PE=1 SV=1"	"5"	"1"	"2"	"1"	"327"	"36.1"	"5.73"	"400.18"	"2.58"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf01398, Pf13012"	"10980"	"ENSG00000168090"	"COPS6"	"A4D2A3; hsa:10980; O15387; Q7L5N1"	"Nucleotide-binding oligomerization domain (NOD) pathway; Ciliary landscape"	"Neddylation; Formation of TC-NER Pre-Incision Complex; DNA Damage Recognition in GG-NER; Cargo recognition for clathrin-mediated endocytosis"	"6"	"0"	"27.7"	"11.1"	"20.5"	"17.3"	"17.3"	"20.1"	"26.3"	"23.6"	"19.3"	"39.0"	"62.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13405"	"39S ribosomal protein L49, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL49 PE=1 SV=1"	"7"	"1"	"1"	"1"	"166"	"19.2"	"9.45"	""	"2.58"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf05046"	"740"	"ENSG00000149792"	"MRPL49"	"B2R4G6; hsa:740; Q13405"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"21.3"	"11.5"	"16.8"	"15.7"	"19.6"	"22.9"	"29.7"	"37.5"	"27.2"	"48.8"	"87.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BSG0"	"Protease-associated domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PRADC1 PE=1 SV=1"	"6"	"1"	"2"	"1"	"188"	"21.0"	"5.47"	"251.76"	"2.58"	"1"	"1"	""	"non-structural extracellular"	""	"Pf02225"	"84279"	"ENSG00000135617"	"PRADC1"	"hsa:84279; Q2Z1P2; Q9BSG0"	""	""	"0"	"0"	"16.3"	"17.9"	"27.7"	"27.2"	"27.5"	"23.4"	"28.9"	"25.6"	"16.9"	"23.9"	"31.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96F85"	"CB1 cannabinoid receptor-interacting protein 1 OS=Homo sapiens OX=9606 GN=CNRIP1 PE=1 SV=1"	"13"	"1"	"1"	"1"	"164"	"18.6"	"7.94"	""	"2.58"	""	"1"	"other biological processes"	"plasma membrane;other membranes;other cell component"	"signal transduction activity or receptor binding"	"Pf15043"	"25927"	"ENSG00000119865"	"CNRIP1"	"B2R4D0; hsa:25927; Q49AN4; Q96F85; Q9UFZ0"	""	""	"0"	"0"	"5.4"	"2.6"	"5.1"	"5.8"	"4.5"	"5.7"	"7.9"	"12.3"	"31.1"	"43.8"	"53.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61201"	"COP9 signalosome complex subunit 2 OS=Homo sapiens OX=9606 GN=COPS2 PE=1 SV=1"	"3"	"1"	"2"	"1"	"443"	"51.6"	"5.53"	"269.13"	"2.58"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01399"	"9318"	"ENSG00000166200"	"COPS2"	"hsa:9318; O88950; P61201; Q15647; Q6FGP4; Q9BY54; Q9R249; Q9UNI2; Q9UNQ5"	"Ciliary landscape"	"Formation of TC-NER Pre-Incision Complex; Neddylation; Cargo recognition for clathrin-mediated endocytosis; RHOBTB1 GTPase cycle; DNA Damage Recognition in GG-NER"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82970"	"High mobility group nucleosome-binding domain-containing protein 5 OS=Homo sapiens OX=9606 GN=HMGN5 PE=1 SV=1"	"3"	"1"	"2"	"1"	"282"	"31.5"	"4.55"	"390.40"	"2.58"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01101"	"79366"	"ENSG00000198157"	"HMGN5"	"hsa:79366; P82970; Q5JSL1"	""	""	"0"	"0"	"109.9"	"74.2"	"89.9"	"74.7"	"92.4"	"97.6"	"164.5"	"139.7"	"106.6"	"196.9"	"240.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N163"	"Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2"	"2"	"2"	"3"	"2"	"923"	"102.8"	"5.22"	"502.58"	"2.57"	"2"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytoskeleton;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf14443, Pf14444, Pf19256, Pf19257"	"57805"	"ENSG00000158941"	"CCAR2"	"A6NL03; B2RB79; D3DSR6; hsa:57805; Q6P0Q9; Q8N163; Q8N3G7; Q8N8M1; Q8TF34; Q9H9Q9; Q9HD12; Q9NT55"	"TAR syndrome"	"Regulation of HSF1-mediated heat shock response"	"2"	"0"	"83.1"	"40.0"	"57.9"	"78.9"	"69.2"	"90.6"	"91.7"	"85.2"	"60.0"	"89.6"	"116.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NI35"	"InaD-like protein OS=Homo sapiens OX=9606 GN=PATJ PE=1 SV=3"	"1"	"2"	"3"	"2"	"1801"	"196.2"	"4.94"	"521.06"	"2.57"	"2"	"1"	"cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	""	"Pf00595, Pf09045"	""	"ENSG00000132849"	"PATJ"	"O15249; O43742; O60833; Q5VUA5; Q5VUA6; Q5VUA7; Q5VUA8; Q5VUA9; Q5VUB0; Q8NI35; Q8WU78; Q9H3N9"	""	"Tight junction interactions; SARS-CoV-2 targets PDZ proteins in cell-cell junction"	"2"	"0"	"75.5"	"47.0"	"72.0"	"59.3"	"67.8"	"71.7"	"107.3"	"114.5"	"83.0"	"111.1"	"135.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96RT1"	"Erbin OS=Homo sapiens OX=9606 GN=ERBIN PE=1 SV=2"	"1"	"1"	"2"	"1"	"1412"	"158.2"	"5.50"	"265.61"	"2.57"	"1"	"1"	"cell adhesion;cell organization and biogenesis;transport;signal transduction;other biological processes"	"extracellular matrix;plasma membrane;other membranes;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity"	"Pf00595, Pf13855"	"55914"	"ENSG00000112851"	"ERBIN"	"A0AVR1; B4E3F1; B7ZLV9; E7EQW9; E9PCR8; hsa:55914; Q1RMD0; Q86W38; Q96RT1; Q9NR18; Q9NW48; Q9ULJ5"	"Nucleotide-binding oligomerization domain (NOD) pathway; Nod-like receptor (NLR) signaling pathway; Pathways affected in adenoid cystic carcinoma"	"RHOC GTPase cycle; RHOA GTPase cycle; RHOB GTPase cycle; RAC1 GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; Downregulation of ERBB2 signaling; Signaling by ERBB2 KD Mutants; Signaling by ERBB2 TMD/JMD mutants; Signaling by ERBB2 ECD mutants; Constitutive Signaling by Overexpressed ERBB2; Drug-mediated inhibition of ERBB2 signaling; Resistance of ERBB2 KD mutants to trastuzumab; Resistance of ERBB2 KD mutants to sapitinib; Resistance of ERBB2 KD mutants to tesevatinib; Resistance of ERBB2 KD mutants to neratinib; Resistance of ERBB2 KD mutants to osimertinib; Resistance of ERBB2 KD mutants to afatinib; Resistance of ERBB2 KD mutants to AEE788; Resistance of ERBB2 KD mutants to lapatinib; Drug resistance in ERBB2 TMD/JMD mutants"	"26"	"0"	"15.4"	"5.4"	"13.0"	"9.5"	"8.0"	"10.7"	"16.5"	"13.7"	"12.4"	"23.9"	"29.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBB4"	"Ataxin-10 OS=Homo sapiens OX=9606 GN=ATXN10 PE=1 SV=1"	"1"	"1"	"2"	"1"	"475"	"53.5"	"5.25"	"287.48"	"2.57"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes"	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf09759"	"25814"	"ENSG00000130638"	"ATXN10"	"A6NLC4; B4DG05; hsa:25814; O14998; O15009; Q6I9X4; Q9UBB4"	"Ciliopathies"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3D3"	"28S ribosomal protein S16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS16 PE=1 SV=1"	"9"	"1"	"1"	"1"	"137"	"15.3"	"9.50"	""	"2.57"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;cytosol;mitochondrion;translational apparatus"	"other molecular function"	"Pf00886"	"51021"	"ENSG00000182180"	"MRPS16"	"B4E032; hsa:51021; Q96Q60; Q9Y3D3"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"9.7"	"5.0"	"6.8"	"11.2"	"8.8"	"7.2"	"22.2"	"17.7"	"10.9"	"17.9"	"26.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13330"	"Metastasis-associated protein MTA1 OS=Homo sapiens OX=9606 GN=MTA1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"715"	"80.7"	"9.26"	"316.69"	"2.57"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00249, Pf00320, Pf01426, Pf01448, Pf17226"	"9112"	"ENSG00000182979"	"MTA1"	"A5PLK4; hsa:9112; Q13330; Q86SW2; Q8NFI8; Q96GI8"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; TAR syndrome"	"HDACs deacetylate histones; Potential therapeutics for SARS; Regulation of PTEN gene transcription; RNA Polymerase I Transcription Initiation; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; SUMOylation of transcription factors"	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N122"	"Regulatory-associated protein of mTOR OS=Homo sapiens OX=9606 GN=RPTOR PE=1 SV=1"	"1"	"1"	"1"	"1"	"1335"	"148.9"	"6.89"	""	"2.56"	""	"1"	"cell organization and biogenesis;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00400, Pf02985, Pf14538"	"57521"	"ENSG00000141564"	"RPTOR"	"B2RN36; C6KEF2; F5H7J5; hsa:57521; Q8N122; Q8N4V9; Q8TB32; Q9P2P3"	"AMP-activated protein kinase signaling; Target of rapamycin signaling; PI3K-AKT-mTOR signaling pathway and therapeutic opportunities in prostate cancer; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Clear cell renal cell carcinoma pathways; PI3K-Akt signaling pathway; Thermogenesis; Synaptic signaling pathways associated with autism spectrum disorder; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Head and neck squamous cell carcinoma; Thyroid hormones production and peripheral downstream signaling effects; IL-18 signaling pathway; CAMKK2 pathway; Autophagy; p53 transcriptional gene network; Pleural mesothelioma; Network map of SARS-CoV-2 signaling pathway; GDNF signaling; DYRK1A involvement regarding cell proliferation in brain development; JAK-STAT signaling in the regulation of Beta-cells; Interferon type I signaling pathways"	"Regulation of PTEN gene transcription; TP53 Regulates Metabolic Genes; mTORC1-mediated signalling; Amino acids regulate mTORC1; Macroautophagy; Energy dependent regulation of mTOR by LKB1-AMPK; HSF1-dependent transactivation"	"33"	"0"	"5.4"	"3.5"	"6.1"	"5.6"	"5.4"	"5.3"	"19.4"	"19.7"	"13.6"	"25.1"	"25.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O96008"	"Mitochondrial import receptor subunit TOM40 homolog OS=Homo sapiens OX=9606 GN=TOMM40 PE=1 SV=1"	"3"	"1"	"2"	"1"	"361"	"37.9"	"7.25"	"274.91"	"2.56"	"1"	"1"	"cell organization and biogenesis;transport"	"other membranes;cytosol;mitochondrion;other cell component"	"transporter activity"	"Pf01459"	"10452"	"ENSG00000130204"	"TOMM40"	"A0A024R0P9; hsa:10452; O96008; Q86VW4; Q8WY09; Q8WY10; Q8WY11; Q9BR95"	"IL-18 signaling pathway"	"Mitochondrial protein import; PINK1-PRKN Mediated Mitophagy"	"3"	"0"	"13.1"	"7.7"	"13.2"	"4.5"	"10.1"	"14.3"	"13.9"	"4.6"	"5.4"	"14.5"	"13.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15541"	"E3 ubiquitin-protein ligase RNF113A OS=Homo sapiens OX=9606 GN=RNF113A PE=1 SV=1"	"3"	"1"	"2"	"1"	"343"	"38.8"	"5.69"	"279.64"	"2.56"	"1"	"1"	"protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus"	"other molecular function"	"Pf00642, Pf13920"	"7737"	"ENSG00000125352"	"RNF113A"	"B2RBR7; hsa:7737; O15541"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"16.6"	"10.7"	"13.9"	"12.9"	"15.2"	"18.9"	"26.2"	"29.5"	"21.5"	"37.3"	"47.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16637"	"Survival motor neuron protein OS=Homo sapiens OX=9606 GN=SMN1 PE=1 SV=1"	"3"	"1"	"2"	"1"	"294"	"31.8"	"6.55"	"279.82"	"2.56"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06003"	"6606; 6607"	"ENSG00000172062; ENSG00000205571; ENSG00000273772; ENSG00000275349; ENSG00000277773"	"SMN1; SMN2"	"A8K0V4; hsa:6606; hsa:6607; Q13119; Q16637; Q549U5; Q96J51"	""	"snRNP Assembly; SARS-CoV-2 modulates host translation machinery"	"2"	"0"	"23.1"	"15.3"	"20.1"	"16.2"	"21.3"	"20.7"	"39.5"	"30.4"	"11.8"	"30.6"	"46.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99961"	"Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1"	"4"	"1"	"2"	"1"	"368"	"41.5"	"5.43"	"235.73"	"2.55"	"1"	"1"	"cell organization and biogenesis;transport;developmental processes;signal transduction"	"other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00018, Pf03114"	"6455"	"ENSG00000141985"	"SH3GL1"	"B4DRA1; E7EVZ4; hsa:6455; M0QZV5; Q99668; Q99961"	"Fragile X syndrome"	"Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation; Negative regulation of MET activity; InlB-mediated entry of Listeria monocytogenes into host cell"	"6"	"0"	"9.5"	"6.3"	"9.3"	"11.3"	"7.4"	"11.2"	"17.0"	"13.8"	"10.5"	"18.8"	"36.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EL3"	"39S ribosomal protein L53, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL53 PE=1 SV=1"	"13"	"1"	"2"	"1"	"112"	"12.1"	"8.76"	"436.53"	"2.55"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	""	"Pf10780"	"116540"	"ENSG00000204822"	"MRPL53"	"hsa:116540; Q96EL3"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"41.7"	"18.3"	"24.3"	"26.8"	"27.6"	"31.7"	"64.7"	"47.3"	"29.9"	"40.2"	"67.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q17R31"	"Putative deoxyribonuclease TATDN3 OS=Homo sapiens OX=9606 GN=TATDN3 PE=1 SV=1"	"7"	"1"	"2"	"1"	"274"	"30.3"	"7.15"	"293.07"	"2.54"	"1"	"1"	""	"nucleus"	"other molecular function"	"Pf01026"	"128387"	"ENSG00000203705"	"TATDN3"	"A6NGS3; B7Z1C1; B7Z978; B7ZLQ6; E9PJE5; E9PNH3; G3V151; hsa:128387; Q17R31; Q4G0L1"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TAE8"	"Growth arrest and DNA damage-inducible proteins-interacting protein 1 OS=Homo sapiens OX=9606 GN=GADD45GIP1 PE=1 SV=1"	"7"	"1"	"2"	"1"	"222"	"25.4"	"10.02"	"306.24"	"2.54"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	""	"Pf10147"	"90480"	"ENSG00000179271"	"GADD45GIP1"	"hsa:90480; Q8IVM3; Q8TAE8; Q8TE51; Q969P9; Q9BSM6"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"20.2"	"24.7"	"24.2"	"18.3"	"20.3"	"22.7"	"46.0"	"42.4"	"35.9"	"50.3"	"51.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02040"	"A-kinase anchor protein 17A OS=Homo sapiens OX=9606 GN=AKAP17A PE=1 SV=2"	"1"	"1"	"2"	"1"	"695"	"80.7"	"9.73"	"376.12"	"2.54"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus"	"other molecular function"	""	"8227"	"ENSG00000197976"	"AKAP17A"	"hsa:8227; Q02040; Q02832; Q2TB98; Q5JQ74; Q5JQ76; Q8N6U9"	""	""	"0"	"0"	"41.2"	"31.6"	"44.5"	"31.1"	"51.3"	"48.3"	"91.1"	"82.1"	"65.9"	"123.9"	"175.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86X29"	"Lipolysis-stimulated lipoprotein receptor OS=Homo sapiens OX=9606 GN=LSR PE=1 SV=4"	"2"	"1"	"1"	"1"	"649"	"71.4"	"7.97"	""	"2.54"	""	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;other cell component"	""	"Pf05624"	"51599"	"ENSG00000105699"	"LSR"	"A6NDW3; B4DKL4; E9PHD4; hsa:51599; O00112; O00426; Q6ZT80; Q86X29; Q8NBM0; Q9BT33; Q9UQL3"	""	"LDL clearance; VLDL clearance"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99504"	"Eyes absent homolog 3 OS=Homo sapiens OX=9606 GN=EYA3 PE=1 SV=3"	"2"	"1"	"2"	"1"	"573"	"62.6"	"5.21"	"397.26"	"2.54"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	""	"2140"	"ENSG00000158161"	"EYA3"	"A8K190; B4DIR7; B4DNZ7; hsa:2140; O95463; Q8IVX7; Q99504; Q99813"	""	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NFT6"	"Protein DBF4 homolog B OS=Homo sapiens OX=9606 GN=DBF4B PE=1 SV=1"	"1"	"1"	"2"	"1"	"615"	"67.2"	"8.34"	"296.46"	"2.54"	"1"	"1"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf07535"	"80174"	"ENSG00000161692"	"DBF4B"	"D3DX56; hsa:80174; Q8NFT6; Q8TEX0; Q96B19; Q9H912"	""	""	"0"	"0"	"207.9"	"111.4"	"163.5"	"103.2"	"157.0"	"156.7"	"319.5"	"265.3"	"182.4"	"332.9"	"526.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96CN9"	"GRIP and coiled-coil domain-containing protein 1 OS=Homo sapiens OX=9606 GN=GCC1 PE=1 SV=1"	"1"	"1"	"1"	"1"	"775"	"87.8"	"5.45"	""	"2.53"	""	"1"	""	"other membranes;cytosol;ER/Golgi"	"other molecular function"	"Pf01465"	"79571"	"ENSG00000179562"	"GCC1"	"hsa:79571; Q96CN9; Q9H6N7"	"Nuclear receptors meta-pathway"	"Retrograde transport at the Trans-Golgi-Network"	"2"	"0"	"103.5"	"70.5"	"85.9"	"96.7"	"95.9"	"101.1"	"188.0"	"151.2"	"101.8"	"178.5"	"281.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WVM7"	"Cohesin subunit SA-1 OS=Homo sapiens OX=9606 GN=STAG1 PE=1 SV=3"	"1"	"1"	"2"	"1"	"1258"	"144.3"	"5.59"	"258.14"	"2.53"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf08514"	"10274"	"ENSG00000118007"	"STAG1"	"hsa:10274; O00539; Q6P275; Q8WVM7"	"Cell cycle; Regulation of sister chromatid separation at the metaphase-anaphase transition; 10q22q23 copy number variation"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Meiotic synapsis; Estrogen-dependent gene expression; SUMOylation of DNA damage response and repair proteins; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"10"	"0"	"125.7"	"58.0"	"89.5"	"60.5"	"87.7"	"94.2"	"183.8"	"153.8"	"108.3"	"181.5"	"259.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A6NKF1"	"SAC3 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SAC3D1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"404"	"43.5"	"8.69"	"292.16"	"2.52"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus;other cell component"	""	"Pf03399"	""	""	"SAC3D1"	"A6NKF1; A8MX08; Q99773"	""	""	"0"	"0"	"24.2"	"14.5"	"23.1"	"19.3"	"19.5"	"20.9"	"36.3"	"23.8"	"27.0"	"24.2"	"40.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16204"	"Coiled-coil domain-containing protein 6 OS=Homo sapiens OX=9606 GN=CCDC6 PE=1 SV=2"	"2"	"1"	"2"	"1"	"474"	"53.3"	"7.34"	"235.93"	"2.52"	"1"	"1"	"cell organization and biogenesis"	"cytosol;cytoskeleton"	"cytoskeletal activity;other molecular function"	"Pf09755"	"8030"	"ENSG00000108091"	"CCDC6"	"hsa:8030; Q15250; Q16204; Q6GSG7"	"Retinoblastoma gene in cancer; Mesodermal commitment pathway; 16p11.2 proximal deletion syndrome"	""	"3"	"0"	"46.9"	"26.6"	"26.6"	"35.3"	"32.1"	"49.2"	"89.2"	"89.6"	"81.1"	"90.0"	"119.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P36915"	"Guanine nucleotide-binding protein-like 1 OS=Homo sapiens OX=9606 GN=GNL1 PE=1 SV=2"	"3"	"1"	"2"	"1"	"607"	"68.6"	"5.80"	"336.81"	"2.52"	"1"	"1"	"stress response;signal transduction;other biological processes"	"non-structural extracellular"	"other molecular function"	"Pf01926"	"2794"	"ENSG00000204590; ENSG00000206492; ENSG00000226882; ENSG00000228581; ENSG00000229470; ENSG00000232143; ENSG00000235986"	"GNL1"	"B0S838; hsa:2794; P36915; Q96CT5"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9BZF9"	"Uveal autoantigen with coiled-coil domains and ankyrin repeats OS=Homo sapiens OX=9606 GN=UACA PE=1 SV=2"	"1"	"1"	"2"	"1"	"1416"	"162.4"	"7.03"	"291.34"	"2.52"	"1"	"1"	"other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus"	"cytoskeletal activity"	"Pf12796"	"55075"	"ENSG00000137831"	"UACA"	"G3XAG2; hsa:55075; Q14DD3; Q8N3B8; Q96NH6; Q9BZF9; Q9HCL1; Q9NWC6"	""	"Regulation of the apoptosome activity; RHOH GTPase cycle"	"2"	"0"	"6.2"	"2.3"	"9.5"	"3.0"	"6.7"	"5.6"	"16.4"	"16.0"	"12.5"	"32.1"	"64.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31939"	"Bifunctional purine biosynthesis protein PURH OS=Homo sapiens OX=9606 GN=ATIC PE=1 SV=3"	"2"	"1"	"2"	"1"	"592"	"64.6"	"6.71"	"253.51"	"2.51"	"1"	"1"	"other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol"	"other molecular function"	"Pf01808, Pf02142"	"471"	"ENSG00000138363"	"ATIC"	"A8K202; E9PBU3; hsa:471; P31939; Q13856; Q53S28"	"One-carbon metabolism"	"Signaling by ALK fusions and activated point mutants; Purine ribonucleoside monophosphate biosynthesis"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NZM3"	"Intersectin-2 OS=Homo sapiens OX=9606 GN=ITSN2 PE=1 SV=3"	"1"	"1"	"2"	"1"	"1697"	"193.3"	"8.12"	"294.65"	"2.51"	"1"	"1"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00018, Pf00168, Pf00621, Pf07653, Pf12763, Pf14604, Pf16652"	"50618"	"ENSG00000198399"	"ITSN2"	"hsa:50618; O95062; Q15812; Q9HAK4; Q9NXE6; Q9NYG0; Q9NZM2; Q9NZM3; Q9ULG4"	""	"Cargo recognition for clathrin-mediated endocytosis; RHOU GTPase cycle"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"O43396"	"Thioredoxin-like protein 1 OS=Homo sapiens OX=9606 GN=TXNL1 PE=1 SV=3"	"4"	"1"	"2"	"1"	"289"	"32.2"	"4.96"	"241.04"	"2.51"	"1"	"1"	""	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00085, Pf06201"	"9352"	"ENSG00000091164"	"TXNL1"	"hsa:9352; O43396"	""	"RND2 GTPase cycle; RHOV GTPase cycle; RHOU GTPase cycle; RND3 GTPase cycle; RND1 GTPase cycle; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle"	"7"	"0"	"18.3"	"12.6"	"25.1"	"15.6"	"21.7"	"20.3"	"32.8"	"28.6"	"32.3"	"42.7"	"55.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H2U2"	"Inorganic pyrophosphatase 2, mitochondrial OS=Homo sapiens OX=9606 GN=PPA2 PE=1 SV=2"	"2"	"1"	"2"	"1"	"334"	"37.9"	"7.39"	"345.80"	"2.51"	"1"	"1"	"other metabolic processes;other biological processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf00719"	"27068"	"ENSG00000138777"	"PPA2"	"B4DLP7; F8WDN9; hsa:27068; I6L9B6; Q4W5E9; Q6PG51; Q8TBW0; Q96E55; Q9H0T0; Q9H2U2; Q9NX37; Q9P033; Q9ULX0"	""	"Mitochondrial tRNA aminoacylation; Pyrophosphate hydrolysis"	"2"	"0"	"18.5"	"8.6"	"13.5"	"11.2"	"11.7"	"16.0"	"17.6"	"16.8"	"16.4"	"25.9"	"38.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96TC7"	"Regulator of microtubule dynamics protein 3 OS=Homo sapiens OX=9606 GN=RMDN3 PE=1 SV=2"	"2"	"1"	"2"	"1"	"470"	"52.1"	"5.10"	"310.41"	"2.50"	"1"	"1"	"other biological processes"	"other membranes;cytoskeleton;mitochondrion;nucleus;other cell component"	"cytoskeletal activity"	""	"55177"	"ENSG00000137824"	"RMDN3"	"A9UMZ9; B3KRR3; hsa:55177; Q6ZWE9; Q96H23; Q96SD6; Q96TC7; Q9H6G1; Q9NVQ6"	""	""	"0"	"0"	"47.4"	"30.2"	"43.4"	"37.9"	"41.2"	"49.0"	"76.1"	"74.0"	"60.0"	"89.7"	"126.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51160"	"Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' OS=Homo sapiens OX=9606 GN=PDE6C PE=1 SV=2"	"1"	"1"	"2"	"1"	"858"	"99.1"	"5.72"	"316.29"	"2.50"	"1"	"1"	"developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes"	"other molecular function"	"Pf00233, Pf01590"	"5146"	"ENSG00000095464"	"PDE6C"	"A6NCR6; hsa:5146; P51160; Q5VY29"	"Phosphodiesterases in neuronal function"	""	"1"	"0"	"38.4"	"19.9"	"33.2"	"23.8"	"30.9"	"38.0"	"70.6"	"68.5"	"69.7"	"118.3"	"213.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z406"	"Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2"	"1"	"2"	"3"	"1"	"1995"	"227.7"	"5.60"	"599.97"	"2.50"	"2"	"1"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00063, Pf01576, Pf02736"	"79784"	"ENSG00000105357"	"MYH14"	"B0I1S2; C3TTN4; hsa:79784; Q5CZ75; Q6XYE4; Q76B62; Q7Z406; Q8WV23; Q96I22; Q9BT27; Q9BW35; Q9H882"	""	"RHO GTPases activate CIT; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; RHO GTPases activate PAKs"	"6"	"0"	"13.3"	"8.4"	"9.2"	"7.8"	"8.3"	"7.6"	"21.9"	"16.6"	"12.3"	"22.4"	"31.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82664"	"28S ribosomal protein S10, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS10 PE=1 SV=2"	"5"	"1"	"1"	"1"	"201"	"23.0"	"8.00"	""	"2.50"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	""	"Pf00338"	"55173"	"ENSG00000048544"	"MRPS10"	"B2RE89; hsa:55173; P82664; Q9H3E5; Q9NVR3"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"31.4"	"11.6"	"26.9"	"19.3"	"22.5"	"29.0"	"55.3"	"44.5"	"28.9"	"58.2"	"98.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75179"	"Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3"	"0"	"1"	"2"	"1"	"2603"	"274.1"	"6.52"	"300.81"	"2.50"	"1"	"1"	"stress response;developmental processes;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf00013, Pf12796"	"26057"	"ENSG00000132466"	"ANKRD17"	"E7EUV3; G5E964; hsa:26057; O75179; Q6PJ85; Q6PK85; Q6PKA2; Q86XI3; Q8NDR5; Q96I86; Q9H288; Q9H6J9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86W92"	"Liprin-beta-1 OS=Homo sapiens OX=9606 GN=PPFIBP1 PE=1 SV=2"	"2"	"1"	"1"	"1"	"1011"	"114.0"	"5.55"	""	"2.50"	""	"1"	"cell adhesion;cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf00536, Pf07647"	"8496"	"ENSG00000110841"	"PPFIBP1"	"hsa:8496; O75336; Q86W92; Q86X70; Q9NY03; Q9ULJ0"	""	"Signaling by ALK fusions and activated point mutants; Receptor-type tyrosine-protein phosphatases"	"2"	"0"	"26.7"	"20.7"	"27.3"	"23.6"	"26.9"	"24.6"	"87.4"	"72.3"	"57.1"	"63.8"	"83.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4X5"	"E3 ubiquitin-protein ligase ARIH1 OS=Homo sapiens OX=9606 GN=ARIH1 PE=1 SV=2"	"2"	"1"	"1"	"1"	"557"	"64.1"	"5.08"	""	"2.50"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01485, Pf19422"	"25820"	"ENSG00000166233"	"ARIH1"	"B2R6U3; hsa:25820; O76026; Q9H3T6; Q9UEN0; Q9UP39; Q9Y4X5"	""	"ISG15 antiviral mechanism"	"1"	"0"	"8.0"	"3.5"	"7.9"	"6.1"	"4.5"	"7.2"	"12.5"	"13.3"	"9.5"	"19.5"	"31.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09001"	"39S ribosomal protein L3, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL3 PE=1 SV=1"	"3"	"1"	"2"	"1"	"348"	"38.6"	"9.48"	"331.81"	"2.50"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00297"	"11222"	"ENSG00000114686"	"MRPL3"	"hsa:11222; P09001; Q6IBT2"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"27.7"	"25.8"	"27.0"	"25.4"	"29.3"	"39.7"	"43.2"	"54.0"	"34.6"	"63.2"	"80.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N5I2"	"Arrestin domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ARRDC1 PE=1 SV=1"	"3"	"1"	"2"	"1"	"433"	"46.0"	"7.02"	"286.47"	"2.49"	"1"	"1"	"protein metabolism;other metabolic processes;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00339, Pf02752"	"92714"	"ENSG00000197070"	"ARRDC1"	"hsa:92714; Q8N5I2"	""	""	"0"	"0"	"5.2"	"0.0"	"6.3"	"2.6"	"7.6"	"1.9"	"7.7"	"9.9"	"11.2"	"25.5"	"37.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95816"	"BAG family molecular chaperone regulator 2 OS=Homo sapiens OX=9606 GN=BAG2 PE=1 SV=1"	"5"	"1"	"1"	"1"	"211"	"23.8"	"6.70"	""	"2.49"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	""	"9532"	"ENSG00000112208"	"BAG2"	"B4DXE2; hsa:9532; O95816; Q08AS9; Q6FID0"	"Pleural mesothelioma"	"Regulation of HSF1-mediated heat shock response"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14880"	"Microsomal glutathione S-transferase 3 OS=Homo sapiens OX=9606 GN=MGST3 PE=1 SV=1"	"5"	"1"	"2"	"1"	"152"	"16.5"	"9.38"	"296.08"	"2.49"	"1"	"1"	"other metabolic processes;other biological processes"	"other membranes;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf01124"	"4259"	"ENSG00000143198"	"MGST3"	"B2R592; hsa:4259; O14880; Q6ICN4"	"Nuclear receptors meta-pathway; NRF2 pathway; Metapathway biotransformation Phase I and II"	"Aflatoxin activation and detoxification; Glutathione conjugation"	"5"	"0"	"243.4"	"126.6"	"177.9"	"144.3"	"182.6"	"211.8"	"260.6"	"199.4"	"115.2"	"299.7"	"393.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TER0"	"Sushi, nidogen and EGF-like domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNED1 PE=2 SV=2"	"1"	"1"	"1"	"1"	"1413"	"152.1"	"6.98"	""	"2.49"	""	"1"	"cell adhesion"	"non-structural extracellular;extracellular matrix"	"signal transduction activity or receptor binding;other molecular function"	"Pf00008, Pf00041, Pf06119, Pf12661"	"25992"	"ENSG00000162804"	"SNED1"	"B5MDC3; B7WNK6; B7WPM0; hsa:25992; Q336F4; Q336F5; Q8N369; Q8TEP7; Q8TER0"	"2q37 copy number variation syndrome"	""	"1"	"0"	"172.7"	"80.3"	"121.5"	"124.2"	"135.0"	"113.2"	"462.2"	"319.7"	"187.6"	"374.7"	"552.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6UB35"	"Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1"	"1"	"1"	"2"	"1"	"978"	"105.7"	"8.06"	"274.39"	"2.49"	"1"	"1"	"other metabolic processes;developmental processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf00763, Pf01268, Pf02882"	"25902"	"ENSG00000120254"	"MTHFD1L"	"hsa:25902; Q2TBF3; Q6UB35; Q8WVW0; Q96HG8; Q9H789; Q9UFU8"	"One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways"	"Metabolism of folate and pterines"	"3"	"0"	"56.2"	"36.7"	"55.5"	"55.7"	"61.5"	"62.5"	"124.0"	"108.1"	"77.1"	"108.4"	"142.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P28482"	"Mitogen-activated protein kinase 1 OS=Homo sapiens OX=9606 GN=MAPK1 PE=1 SV=3"	"6"	"3"	"4"	"3"	"360"	"41.4"	"6.98"	"833.47"	"2.49"	"3"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00069"	"5594"	"ENSG00000100030"	"MAPK1"	"A8CZ64; hsa:5594; P28482"	"IL-5 signaling pathway; Osteopontin signaling; Physiological and pathological hypertrophy of the heart; Angiogenesis; MicroRNAs in cardiomyocyte hypertrophy; Type II diabetes mellitus; Heart development; Integrin-mediated cell adhesion; IL-1 signaling pathway; Thyroxine (thyroid hormone) production; RANKL/RANK signaling pathway; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Follicle stimulating hormone (FSH) signaling pathway; TNF-related weak inducer of apoptosis (TWEAK) signaling pathway; Prolactin signaling pathway; IL-7 signaling pathway; Alzheimer's disease and miRNA effects; IL-17 signaling pathway; Endothelin pathways; IL-9 signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; Glioblastoma signaling pathways; Androgen receptor network in prostate cancer; B cell receptor signaling pathway; TNF-alpha signaling pathway; AGE/RAGE pathway; Interleukin-11 signaling pathway; Corticotropin-releasing hormone signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Spinal cord injury; Alpha 6 beta 4 signaling pathway; PDGF pathway; Aryl hydrocarbon receptor pathway; S1P receptor signal transduction; Ebstein-Barr virus LMP1 signaling; Common pathways underlying drug addiction; Interleukin-1 (IL-1) structural pathway; Cardiac hypertrophic response; Bladder cancer; IL-3 signaling pathway; Apoptosis-related network due to altered Notch3 in ovarian cancer; TCA cycle nutrient use and invasiveness of ovarian cancer; Kit receptor signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; MFAP5-mediated ovarian cancer cell motility and invasiveness; RAC1/PAK1/p38/MMP2 pathway; Wnt signaling pathway; IL6 signaling pathway; Hypothesized pathways in pathogenesis of cardiovascular disease; BDNF-TrkB signaling; Physico-chemical features and toxicity-associated pathways; MAPK signaling pathway; MAPK and NFkB signaling pathways inhibited by Yersinia YopJ; ERK pathway in Huntington's disease; Toll-like receptor signaling related to MyD88; TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition; 4-hydroxytamoxifen, dexamethasone, and retinoic acids regulation of p27 expression; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Chemokine signaling pathway; Embryonic stem cell pluripotency pathways; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; IL-4 signaling pathway; Prion disease pathway; Endometrial cancer; PI3K-Akt signaling pathway; Chromosomal and microsatellite instability in colorectal cancer ; Ebola virus infection in host; MAPK cascade; Ras signaling; Epithelial to mesenchymal transition in colorectal cancer; Non-small cell lung cancer; Breast cancer pathway; Pancreatic adenocarcinoma pathway; Acute viral myocarditis; Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells; Neovascularisation processes; Non-genomic actions of 1,25 dihydroxyvitamin D3; EGF/EGFR signaling pathway; Bile acids synthesis and enterohepatic circulation ; Resistin as a regulator of inflammation; Relationship between inflammation, COX-2 and EGFR; Envelope proteins and their potential roles in EDMD physiopathology; Regulatory circuits of the STAT3 signaling pathway; Synaptic signaling pathways associated with autism spectrum disorder; Fragile X syndrome; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Translation inhibitors in chronically activated PDGFRA cells; Gastrin signaling pathway; Hepatitis B infection; Melanoma; Netrin-UNC5B signaling pathway; IL-18 signaling pathway; FGFR3 signaling in chondrocyte proliferation and terminal differentiation; Osteoblast differentiation and related diseases; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; Regucalcin in proximal tubule epithelial kidney cells; Kisspeptin/kisspeptin receptor system in the ovary; MAP3K1 role in promoting and blocking gonadal determination; CAMKK2 pathway; Disruption of postsynaptic signaling by CNV; Host-pathogen interaction of human coronaviruses - MAPK signaling; IL-2 signaling pathway; RAS and bradykinin pathways in COVID-19; Angiotensin II receptor type 1 pathway; Kallmann syndrome; Neuroinflammation and glutamatergic signaling; Pleural mesothelioma; Orexin receptor pathway; CCL18 signaling pathway; Regulation of actin cytoskeleton; Sphingolipid metabolism in senescence; Alzheimer's disease; Th17 cell differentiation pathway; GDNF signaling; 2q11.2 copy number variation syndrome; 2q13 copy number variation syndrome; Hippocampal synaptogenesis and neurogenesis; Comprehensive IL-17A signaling; Genetic causes of porto-sinusoidal vascular disease; Female steroid hormones in cardiomyocyte energy metabolism; Cardiomyocyte signaling pathways converging on Titin; 8p23.1 copy number variation syndrome; IL-26 signaling pathways; A network map of Macrophage-stimulating protein (MSP) signaling; 4p16.3 copy number variation; Role of hypoxia, angiogenesis, and FGF pathway in OA chondrocyte hypertrophy; NPHP1 deletion syndrome; EPO receptor signaling; ErbB signaling pathway; T-cell receptor signaling pathway; DNA damage response (only ATM dependent); Estrogen signaling pathway; Vitamin A and carotenoid metabolism; Toll-like receptor signaling pathway"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Neutrophil degranulation; Recycling pathway of L1; FCERI mediated MAPK activation; NPAS4 regulates expression of target genes; Regulation of HSF1-mediated heat shock response; Signaling by BRAF and RAF1 fusions; Thrombin signalling through proteinase activated receptors (PARs); SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Oxidative Stress Induced Senescence; Regulation of PTEN gene transcription; Signaling by NODAL; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Interferon gamma signaling; Oncogene Induced Senescence; Senescence-Associated Secretory Phenotype (SASP); Growth hormone receptor signaling; Regulation of the apoptosome activity; Signal transduction by L1; Estrogen-dependent nuclear events downstream of ESR-membrane signaling; NCAM signaling for neurite out-growth; Downregulation of SMAD2/3:SMAD4 transcriptional activity; RUNX2 regulates osteoblast differentiation; RSK activation; Estrogen-stimulated signaling through PRKCZ; Spry regulation of FGF signaling; Suppression of apoptosis; MAPK1 (ERK2) activation; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; IFNG signaling activates MAPKs; Golgi Cisternae Pericentriolar Stack Reorganization; Signaling by Activin; Activation of the AP-1 family of transcription factors; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; Frs2-mediated activation; Signal attenuation; Gastrin-CREB signalling pathway via PKC and MAPK; Nuclear events stimulated by ALK signaling in cancer; ESR-mediated signaling; Negative feedback regulation of MAPK pathway; Advanced glycosylation endproduct receptor signaling; RHO GTPases Activate NADPH Oxidases; ERKs are inactivated; Signaling by MAP2K mutants; phospho-PLA2 pathway; Signaling by MAPK mutants"	"200"	"0"	"385.1"	"133.5"	"225.0"	"278.1"	"247.4"	"315.1"	"591.2"	"547.2"	"449.1"	"698.4"	"1128.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15120"	"[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial OS=Homo sapiens OX=9606 GN=PDK3 PE=1 SV=1"	"2"	"1"	"2"	"1"	"406"	"46.9"	"8.37"	"325.86"	"2.49"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"mitochondrion;nucleus"	"kinase activity;other molecular function"	"Pf02518, Pf10436"	"5165"	"ENSG00000067992"	"PDK3"	"B4DXG6; hsa:5165; Q15120"	""	"Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid"	"2"	"0"	"44.2"	"31.3"	"39.6"	"36.1"	"40.7"	"48.1"	"208.0"	"232.1"	"190.1"	"248.5"	"357.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96SB4"	"SRSF protein kinase 1 OS=Homo sapiens OX=9606 GN=SRPK1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"655"	"74.3"	"6.16"	"323.99"	"2.49"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"6732"	"ENSG00000096063"	"SRPK1"	"B4DS61; hsa:6732; Q12890; Q5R364; Q5R365; Q8IY12; Q96SB4"	"VEGFA-VEGFR2 signaling; mRNA processing"	"Maturation of nucleoprotein"	"3"	"0"	"17.1"	"13.7"	"23.3"	"19.0"	"27.7"	"17.0"	"56.8"	"42.6"	"29.7"	"63.3"	"69.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96T58"	"Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1"	"0"	"2"	"3"	"1"	"3664"	"402.0"	"7.64"	"586.35"	"2.49"	"2"	"1"	"signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf07744"	"23013"	"ENSG00000065526"	"SPEN"	"hsa:23013; Q96T58; Q9H9A8; Q9NWH5; Q9UQ01; Q9Y556"	"Notch signaling pathway"	"RHOBTB1 GTPase cycle"	"2"	"0"	"32.0"	"20.0"	"21.9"	"28.8"	"27.6"	"41.1"	"75.0"	"78.7"	"70.1"	"70.3"	"74.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15843"	"NEDD8 OS=Homo sapiens OX=9606 GN=NEDD8 PE=1 SV=1"	"14"	"1"	"2"	"1"	"81"	"9.1"	"8.43"	"277.58"	"2.49"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00240"	"4738"	"ENSG00000129559; ENSG00000285246"	"NEDD8"	"hsa:4738; Q15843; Q3SXN8; Q6LES6"	"EGF/EGFR signaling pathway; 2q37 copy number variation syndrome"	"UCH proteinases; Neddylation; Cargo recognition for clathrin-mediated endocytosis; Iron uptake and transport; TGF-beta receptor signaling activates SMADs"	"7"	"0"	"49.7"	"26.3"	"38.7"	"22.4"	"35.9"	"39.0"	"58.7"	"55.2"	"48.7"	"65.8"	"118.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NVA1"	"Ubiquinol-cytochrome-c reductase complex assembly factor 1 OS=Homo sapiens OX=9606 GN=UQCC1 PE=1 SV=3"	"4"	"1"	"2"	"1"	"299"	"34.6"	"8.91"	"288.10"	"2.48"	"1"	"1"	"cell organization and biogenesis"	"other membranes;mitochondrion;other cell component"	""	"Pf03981"	"55245"	"ENSG00000101019"	"UQCC1"	"B1AKV5; hsa:55245; Q0VF37; Q5T348; Q5T351; Q5T353; Q86YU3; Q86YU4; Q96H66; Q9H438; Q9H452; Q9H9K8; Q9H9R5; Q9NVA1"	"Ciliary landscape; Mitochondrial complex III assembly"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31153"	"S-adenosylmethionine synthase isoform type-2 OS=Homo sapiens OX=9606 GN=MAT2A PE=1 SV=1"	"2"	"1"	"2"	"1"	"395"	"43.6"	"6.48"	"277.99"	"2.48"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00438, Pf02772, Pf02773"	"4144"	"ENSG00000168906"	"MAT2A"	"A8K511; B4DN45; D6W5L1; hsa:4144; P31153; Q53SP5"	"Trans-sulfuration, one-carbon metabolism and related pathways; Methionine de novo and salvage pathway; Methylation pathways"	"Methylation"	"4"	"0"	"147.4"	"101.4"	"130.1"	"108.2"	"128.4"	"136.3"	"160.4"	"146.2"	"130.1"	"179.7"	"233.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q147X3"	"N-alpha-acetyltransferase 30 OS=Homo sapiens OX=9606 GN=NAA30 PE=1 SV=1"	"2"	"1"	"2"	"1"	"362"	"39.3"	"5.52"	"319.86"	"2.48"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00583"	"122830"	"ENSG00000139977"	"NAA30"	"hsa:122830; Q0IIN2; Q147X3"	"Metapathway biotransformation Phase I and II"	"Retrograde transport at the Trans-Golgi-Network"	"2"	"0"	"12.8"	"10.2"	"15.9"	"13.9"	"14.6"	"13.4"	"44.8"	"53.4"	"46.6"	"75.6"	"84.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BW92"	"Threonine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=TARS2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"718"	"81.0"	"7.30"	"311.74"	"2.48"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00587, Pf02824, Pf03129, Pf07973"	"80222"	"ENSG00000143374"	"TARS2"	"hsa:80222; Q53GW7; Q96I50; Q9BW92; Q9H9V2"	""	"Mitochondrial tRNA aminoacylation"	"1"	"0"	"10.3"	"9.0"	"22.3"	"12.7"	"15.4"	"15.1"	"19.9"	"17.5"	"19.3"	"35.0"	"38.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2R9"	"28S ribosomal protein S7, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS7 PE=1 SV=2"	"9"	"2"	"3"	"2"	"242"	"28.1"	"9.99"	"487.24"	"2.47"	"2"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00177"	"51081"	"ENSG00000125445"	"MRPS7"	"B2R9N5; hsa:51081; Q53GD6; Q9Y2R9"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"19.6"	"13.3"	"20.8"	"15.2"	"19.6"	"19.0"	"50.9"	"33.4"	"20.0"	"42.7"	"81.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15555"	"Microtubule-associated protein RP/EB family member 2 OS=Homo sapiens OX=9606 GN=MAPRE2 PE=1 SV=1"	"4"	"1"	"2"	"1"	"327"	"37.0"	"5.57"	"247.13"	"2.47"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf03271"	"10982"	"ENSG00000166974"	"MAPRE2"	"B2RE21; B3KR39; B4DJV4; B7Z2L3; E9PHR3; F5H1V8; G5E9I6; hsa:10982; Q15555; Q9UQ33"	"Ciliary landscape"	""	"1"	"0"	"10.1"	"6.8"	"12.5"	"8.3"	"12.3"	"14.5"	"23.2"	"17.0"	"13.0"	"22.3"	"34.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75554"	"WW domain-binding protein 4 OS=Homo sapiens OX=9606 GN=WBP4 PE=1 SV=1"	"3"	"1"	"2"	"1"	"376"	"42.5"	"5.57"	"300.77"	"2.47"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00397, Pf06220"	"11193"	"ENSG00000120688"	"WBP4"	"B7Z4M2; hsa:11193; O75554; Q32P29"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P47756"	"F-actin-capping protein subunit beta OS=Homo sapiens OX=9606 GN=CAPZB PE=1 SV=4"	"3"	"1"	"2"	"1"	"277"	"31.3"	"5.59"	"290.38"	"2.47"	"1"	"1"	"cell organization and biogenesis"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf01115"	"100612860; 101140941"	"ENSGGOG00000003982; ENSPPYG00000001789; ENSPTRG00000000268"	"CAPZB"	"A0A2J8KEQ9; A0A2J8T2J3; A0A6D2W7V0; A0A6D2XKL1; A0A8B6ZIG4; A0A9B0TL78; G3QN07; H2N8T0; H2R9E0"	""	""	"0"	"0"	"68.6"	"43.0"	"52.9"	"58.8"	"67.2"	"63.1"	"116.6"	"128.8"	"91.6"	"133.7"	"157.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9ULW0"	"Targeting protein for Xklp2 OS=Homo sapiens OX=9606 GN=TPX2 PE=1 SV=2"	"1"	"1"	"2"	"1"	"747"	"85.6"	"9.23"	"277.35"	"2.47"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf06886, Pf09041, Pf12214"	"22974"	"ENSG00000088325"	"TPX2"	"hsa:22974; Q96RR5; Q9H1R4; Q9NRA3; Q9UFN9; Q9UL00; Q9ULW0; Q9Y2M1"	"Gastric cancer network 1"	"Regulation of TP53 Activity through Phosphorylation; AURKA Activation by TPX2"	"3"	"0"	"26.8"	"16.9"	"28.6"	"26.8"	"32.7"	"39.0"	"64.9"	"65.1"	"43.2"	"74.5"	"110.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N9N7"	"Leucine-rich repeat-containing protein 57 OS=Homo sapiens OX=9606 GN=LRRC57 PE=1 SV=1"	"5"	"1"	"1"	"1"	"239"	"26.7"	"8.43"	""	"2.47"	""	"1"	""	"other membranes"	""	"Pf13855"	"255252"	"ENSG00000180979"	"LRRC57"	"hsa:255252; Q7Z2Z6; Q8N1T6; Q8N9N7"	""	""	"0"	"0"	"16.5"	"5.0"	"8.2"	"13.1"	"12.7"	"13.1"	"25.1"	"23.9"	"18.0"	"32.7"	"40.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75695"	"Protein XRP2 OS=Homo sapiens OX=9606 GN=RP2 PE=1 SV=4"	"3"	"1"	"2"	"1"	"350"	"39.6"	"5.12"	"292.57"	"2.47"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf07986"	"6102"	"ENSG00000102218"	"RP2"	"hsa:6102; O75695; Q86XJ7; Q9NU67"	"Joubert syndrome; Ciliopathies; Bardet-Biedl syndrome"	"Trafficking of myristoylated proteins to the cilium"	"4"	"0"	"55.2"	"32.9"	"42.3"	"37.0"	"41.4"	"47.8"	"56.6"	"59.0"	"45.9"	"72.6"	"117.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3E7"	"Charged multivesicular body protein 3 OS=Homo sapiens OX=9606 GN=CHMP3 PE=1 SV=3"	"5"	"1"	"2"	"1"	"222"	"25.1"	"5.12"	"265.66"	"2.47"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf03357"	"100526767; 51652"	"ENSG00000115561"	"CHMP3"	"A8K3W0; B4DG34; B8ZZM0; B8ZZX5; hsa:100526767; hsa:51652; Q3ZTS9; Q53S71; Q53SU5; Q9NZ51; Q9Y3E7"	""	"HCMV Late Events; Macroautophagy; Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT); Late endosomal microautophagy; Sealing of the nuclear envelope (NE) by ESCRT-III; Pyroptosis; Translation of Replicase and Assembly of the Replication Transcription Complex; Translation of Replicase and Assembly of the Replication Transcription Complex"	"9"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BTT6"	"Leucine-rich repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=LRRC1 PE=1 SV=1"	"2"	"1"	"2"	"1"	"524"	"59.2"	"5.02"	"245.71"	"2.47"	"1"	"1"	""	"other membranes;cytosol"	""	"Pf13855"	"55227"	"ENSG00000137269"	"LRRC1"	"hsa:55227; Q5TGN3; Q9BTT6; Q9HAC0; Q9NVF1"	""	"RND2 GTPase cycle"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H7Z3"	"Nuclear exosome regulator NRDE2 OS=Homo sapiens OX=9606 GN=NRDE2 PE=1 SV=3"	"1"	"1"	"2"	"1"	"1164"	"132.6"	"7.68"	"327.08"	"2.46"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus"	""	"Pf08424"	"55051"	"ENSG00000119720"	"NRDE2"	"B4DH71; hsa:55051; Q4G0A7; Q9H7Z3; Q9NWH6"	""	""	"0"	"0"	"12.8"	"9.7"	"14.9"	"19.3"	"17.8"	"15.5"	"46.0"	"54.3"	"45.9"	"67.4"	"81.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62328"	"Thymosin beta-4 OS=Homo sapiens OX=9606 GN=TMSB4X PE=1 SV=2"	"16"	"1"	"2"	"1"	"44"	"5.1"	"5.06"	"309.12"	"2.46"	"1"	"1"	"cell organization and biogenesis;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01290"	"7114"	"ENSG00000205542"	"TMSB4X"	"hsa:7114; P01253; P01254; P62328; Q546P5; Q63576; Q9UE55"	"Genes targeted by miRNAs in adipocytes; VEGFA-VEGFR2 signaling; IL-18 signaling pathway; Regulation of actin cytoskeleton"	"Platelet degranulation"	"5"	"0"	"296.6"	"163.0"	"249.6"	"141.7"	"222.4"	"255.5"	"255.4"	"165.0"	"119.0"	"251.5"	"418.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96CM8"	"Medium-chain acyl-CoA ligase ACSF2, mitochondrial OS=Homo sapiens OX=9606 GN=ACSF2 PE=1 SV=2"	"2"	"1"	"2"	"1"	"615"	"68.1"	"7.55"	"312.03"	"2.46"	"1"	"1"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00501, Pf13193"	"80221"	"ENSG00000167107"	"ACSF2"	"B4DFQ6; B4DHT5; B4DUF5; hsa:80221; Q96CM8; Q9H7G2"	"Mitochondrial long chain fatty acid beta-oxidation; Mitochondrial fatty acid oxidation disorders"	"Mitochondrial Fatty Acid Beta-Oxidation"	"3"	"0"	"10.2"	"6.6"	"9.1"	"11.2"	"12.7"	"11.0"	"18.3"	"16.0"	"8.6"	"17.2"	"27.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75962"	"Triple functional domain protein OS=Homo sapiens OX=9606 GN=TRIO PE=1 SV=2"	"0"	"1"	"2"	"1"	"3097"	"346.7"	"6.37"	"257.69"	"2.46"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00018, Pf00069, Pf00169, Pf00435, Pf00621, Pf00650, Pf07679, Pf16609"	"7204"	"ENSG00000038382"	"TRIO"	"D3DTD1; hsa:7204; O75962; Q13458; Q59EQ7; Q6PJC9; Q6ZN05; Q8IWK8"	"Microtubule cytoskeleton regulation; Neural crest cell migration during development; Neural crest cell migration in cancer"	"RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events; RHOG GTPase cycle; G alpha (q) signalling events; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOJ GTPase cycle; DCC mediated attractive signaling"	"14"	"0"	"12.1"	"6.5"	"12.7"	"12.6"	"12.4"	"14.9"	"21.7"	"28.0"	"25.5"	"41.4"	"48.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48201"	"ATP synthase F(0) complex subunit C3, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5MC3 PE=1 SV=1"	"5"	"1"	"2"	"1"	"142"	"14.7"	"9.45"	"310.16"	"2.46"	"1"	"1"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00137"	"518"	"ENSG00000154518"	"ATP5MC3"	"B2R4Z0; D3DPF0; hsa:518; P48201; Q4ZFX7"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"5"	"0"	"149.7"	"75.2"	"136.7"	"73.8"	"119.3"	"115.1"	"503.2"	"1148.6"	"547.5"	"705.2"	"1051.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08758"	"Annexin A5 OS=Homo sapiens OX=9606 GN=ANXA5 PE=1 SV=2"	"3"	"1"	"2"	"1"	"320"	"35.9"	"5.05"	"317.46"	"2.45"	"1"	"1"	"stress response;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00191"	"308"	"ENSG00000164111"	"ANXA5"	"D3DNW7; hsa:308; P08758; Q6FHB3; Q6FI16; Q8WV69; Q9UDH9"	"Apoptosis-related network due to altered Notch3 in ovarian cancer; Interactions between LOXL4 and oxidative stress pathway; Prostaglandin synthesis and regulation"	"Platelet degranulation"	"4"	"0"	"117.1"	"90.4"	"128.9"	"58.1"	"84.1"	"119.8"	"125.1"	"82.7"	"75.0"	"125.2"	"160.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9C037"	"E3 ubiquitin-protein ligase TRIM4 OS=Homo sapiens OX=9606 GN=TRIM4 PE=1 SV=2"	"2"	"1"	"2"	"1"	"500"	"57.4"	"8.10"	""	"2.45"	""	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00622, Pf00643, Pf15227"	"89122"	"ENSG00000146833"	"TRIM4"	"A4D298; hsa:89122; Q75MK1; Q96F06; Q9C036; Q9C037"	""	"SARS-CoV-2 activates/modulates innate and adaptive immune responses; Antigen processing: Ubiquitination & Proteasome degradation; Negative regulators of DDX58/IFIH1 signaling; TRAF6 mediated NF-kB activation; NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10; Ovarian tumor domain proteases; TRAF3-dependent IRF activation pathway; TRAF6 mediated IRF7 activation"	"9"	"0"	"156.5"	"73.5"	"122.8"	"70.4"	"99.6"	"84.7"	"219.6"	"221.7"	"201.4"	"408.4"	"636.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15381"	"Nuclear valosin-containing protein-like OS=Homo sapiens OX=9606 GN=NVL PE=1 SV=1"	"1"	"1"	"2"	"1"	"856"	"95.0"	"6.48"	"388.73"	"2.45"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00004, Pf16725, Pf17862"	"4931"	"ENSG00000143748"	"NVL"	"B4DMC4; B4DP98; hsa:4931; O15381; Q96EM7"	""	""	"0"	"0"	"80.2"	"50.8"	"41.8"	"59.6"	"69.8"	"69.3"	"118.8"	"89.5"	"66.1"	"104.2"	"121.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UK61"	"Protein TASOR OS=Homo sapiens OX=9606 GN=TASOR PE=1 SV=3"	"1"	"1"	"2"	"1"	"1670"	"188.9"	"5.80"	"301.03"	"2.45"	"1"	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf12509"	"23272"	"ENSG00000163946"	"TASOR"	"A1L3A4; B5ME28; hsa:23272; Q9H2F7; Q9UK61; Q9UPP7"	""	""	"0"	"0"	"47.4"	"35.3"	"51.8"	"44.0"	"47.0"	"54.2"	"86.8"	"74.1"	"54.7"	"109.7"	"139.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95983"	"Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1"	"4"	"1"	"2"	"1"	"291"	"32.8"	"5.34"	"356.70"	"2.45"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01429, Pf14048, Pf16564"	"53615"	"ENSG00000071655"	"MBD3"	"A8K4B7; D6W5Z2; hsa:53615; O95983; Q6PIL9; Q6PJZ9; Q86XF4"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"Potential therapeutics for SARS; HDACs deacetylate histones; Regulation of PTEN gene transcription; RNA Polymerase I Transcription Initiation; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of TP53 Activity through Acetylation"	"7"	"0"	"32.5"	"20.5"	"22.5"	"22.8"	"26.1"	"26.8"	"42.8"	"35.1"	"37.7"	"44.0"	"54.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q06203"	"Amidophosphoribosyltransferase OS=Homo sapiens OX=9606 GN=PPAT PE=1 SV=1"	"2"	"1"	"2"	"1"	"517"	"57.4"	"6.76"	"307.71"	"2.45"	"1"	"1"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00156, Pf13522"	"5471"	"ENSG00000128059"	"PPAT"	"hsa:5471; Q06203"	"Fluoropyrimidine activity; Metabolic reprogramming in colon cancer"	"Purine ribonucleoside monophosphate biosynthesis"	"3"	"0"	"46.0"	"28.6"	"36.9"	"46.2"	"41.2"	"40.4"	"65.6"	"66.0"	"52.2"	"80.2"	"124.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P0M9"	"39S ribosomal protein L27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL27 PE=1 SV=1"	"7"	"1"	"2"	"1"	"148"	"16.1"	"10.42"	"384.55"	"2.44"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf01016"	"51264"	"ENSG00000108826"	"MRPL27"	"B2RE14; hsa:51264; Q9P0M9"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"40.8"	"28.6"	"36.4"	"33.6"	"40.3"	"40.3"	"69.5"	"60.4"	"46.4"	"73.2"	"109.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P32238"	"Cholecystokinin receptor type A OS=Homo sapiens OX=9606 GN=CCKAR PE=1 SV=1"	"3"	"1"	"1"	"1"	"428"	"47.8"	"9.20"	""	"2.44"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	"other molecular function"	"Pf00001, Pf09193"	"886"	"ENSG00000163394"	"CCKAR"	"B2R9Z5; hsa:886; P32238"	"Peptide GPCRs; GPCRs, class A rhodopsin-like"	"G alpha (q) signalling events; Peptide ligand-binding receptors"	"4"	"0"	"38.5"	"33.6"	"43.2"	"30.9"	"44.7"	"39.4"	"88.4"	"86.8"	"75.4"	"89.9"	"101.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96C57"	"Protein CUSTOS OS=Homo sapiens OX=9606 GN=CUSTOS PE=1 SV=2"	"4"	"1"	"2"	"1"	"262"	"28.2"	"9.42"	"267.71"	"2.44"	"1"	"1"	"cell-cell signaling;signal transduction;other biological processes"	"nucleus"	""	""	"64897"	"ENSG00000157895"	"CUSTOS"	"hsa:64897; Q53HF0; Q96C57; Q9H9Z7"	""	""	"0"	"0"	"55.5"	"26.1"	"47.5"	"51.7"	"38.1"	"50.6"	"178.0"	"175.3"	"137.8"	"165.4"	"196.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75438"	"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 OS=Homo sapiens OX=9606 GN=NDUFB1 PE=1 SV=1"	"19"	"1"	"1"	"1"	"58"	"7.0"	"8.92"	""	"2.44"	""	"1"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion;nucleus"	"transporter activity"	"Pf08040"	"4707"	"ENSG00000183648"	"NDUFB1"	"A0AV68; hsa:4707; O75438"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42696"	"RNA-binding protein 34 OS=Homo sapiens OX=9606 GN=RBM34 PE=1 SV=2"	"2"	"1"	"2"	"1"	"430"	"48.5"	"10.11"	"285.15"	"2.44"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"23029"	"ENSG00000188739"	"RBM34"	"A8K8J7; hsa:23029; P42696; Q8N2Z8; Q9H5A1"	""	""	"0"	"0"	"27.9"	"20.8"	"19.0"	"25.0"	"29.1"	"30.4"	"78.3"	"81.6"	"68.0"	"111.9"	"121.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61244"	"Protein max OS=Homo sapiens OX=9606 GN=MAX PE=1 SV=1"	"9"	"2"	"3"	"2"	"160"	"18.3"	"6.30"	"527.13"	"2.44"	"2"	"1"	"cell organization and biogenesis;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00010"	"4149"	"ENSG00000125952"	"MAX"	"A6NH73; A8K265; A8K4G4; A8K824; hsa:4149; P25912; P52163; P61244; Q14803; Q96CY8"	"B cell receptor signaling pathway; Pathways affected in adenoid cystic carcinoma; MAPK signaling pathway; p38 MAPK signaling pathway; Small cell lung cancer; Pleural mesothelioma; 5q35 copy number variation"	"Transcriptional Regulation by E2F6; Cyclin E associated events during G1/S transition ; Transcription of E2F targets under negative control by DREAM complex; Cyclin A:Cdk2-associated events at S phase entry"	"11"	"0"	"390.2"	"205.4"	"341.8"	"265.8"	"269.5"	"334.9"	"729.3"	"731.0"	"535.8"	"756.3"	"984.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00013"	"55 kDa erythrocyte membrane protein OS=Homo sapiens OX=9606 GN=MPP1 PE=1 SV=2"	"3"	"1"	"2"	"1"	"466"	"52.3"	"7.37"	"293.97"	"2.43"	"1"	"1"	"other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;kinase activity"	"Pf00018, Pf00595, Pf00625"	"4354"	"ENSG00000130830"	"MPP1"	"B4DZV5; G3XAI1; hsa:4354; Q00013; Q2TSB6; Q5J7V5"	"MECP2 and associated Rett syndrome"	"Sensory processing of sound by outer hair cells of the cochlea"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L0Y3"	"tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2"	"4"	"2"	"3"	"2"	"403"	"47.3"	"9.36"	"499.29"	"2.43"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01746"	"54931"	"ENSG00000174173"	"TRMT10C"	"hsa:54931; Q7L0Y3; Q9NRG5; Q9NX54; Q9Y596"	""	"tRNA processing in the mitochondrion; tRNA modification in the mitochondrion; rRNA processing in the mitochondrion"	"3"	"0"	"44.3"	"19.8"	"34.0"	"29.1"	"34.7"	"36.6"	"103.8"	"94.8"	"67.4"	"119.9"	"176.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BVC3"	"Sister chromatid cohesion protein DCC1 OS=Homo sapiens OX=9606 GN=DSCC1 PE=1 SV=2"	"4"	"1"	"1"	"1"	"393"	"44.8"	"5.17"	""	"2.43"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf09724"	"79075"	"ENSG00000136982"	"DSCC1"	"hsa:79075; Q969N5; Q9BVC3"	"Gastric cancer network 2"	"Polymerase switching on the C-strand of the telomere"	"2"	"0"	"5.6"	"3.8"	"8.4"	"9.2"	"5.4"	"9.9"	"14.3"	"15.5"	"9.8"	"13.7"	"28.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30084"	"Enoyl-CoA hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=ECHS1 PE=1 SV=4"	"4"	"1"	"2"	"1"	"290"	"31.4"	"8.07"	"321.00"	"2.42"	"1"	"1"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00378"	"1892"	"ENSG00000127884"	"ECHS1"	"hsa:1892; O00739; P30084; Q5VWY1; Q96H54"	"Fatty acid beta-oxidation; Fatty acid biosynthesis; Ciliary landscape; Tryptophan metabolism"	"Branched-chain amino acid catabolism; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of butanoyl-CoA to acetyl-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA"	"10"	"0"	"20.9"	"13.6"	"22.8"	"23.3"	"25.2"	"26.3"	"47.2"	"42.6"	"30.7"	"59.2"	"71.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q93008"	"Probable ubiquitin carboxyl-terminal hydrolase FAF-X OS=Homo sapiens OX=9606 GN=USP9X PE=1 SV=3"	"0"	"1"	"1"	"1"	"2570"	"292.1"	"5.80"	""	"2.42"	""	"1"	"protein metabolism;other metabolic processes"	""	"other molecular function"	"Pf00443, Pf12030"	"100971796; 465582"	"ENSPPAG00000039671; ENSPTRG00000045541"	"USP9X"	"A0A2I3RAB4; A0A2J8JDU7; A0A2R9BVD0; A0A6D2WW26"	""	""	"0"	"0"	"16.7"	"8.5"	"21.5"	"19.7"	"19.8"	"18.2"	"34.1"	"39.1"	"27.9"	"34.9"	"41.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43617"	"Trafficking protein particle complex subunit 3 OS=Homo sapiens OX=9606 GN=TRAPPC3 PE=1 SV=1"	"4"	"1"	"2"	"1"	"180"	"20.3"	"4.96"	"308.27"	"2.42"	"1"	"1"	"cell organization and biogenesis;transport"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf04051"	"27095"	"ENSG00000054116"	"TRAPPC3"	"A6NDN0; B2RDN2; D3DPS2; hsa:27095; O43617"	""	"RAB GEFs exchange GTP for GDP on RABs; COPII-mediated vesicle transport"	"2"	"0"	"36.7"	"31.0"	"52.9"	"47.2"	"49.6"	"54.8"	"65.8"	"83.7"	"62.6"	"89.3"	"122.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96CP2"	"FLYWCH family member 2 OS=Homo sapiens OX=9606 GN=FLYWCH2 PE=1 SV=1"	"6"	"1"	"2"	"1"	"140"	"14.6"	"8.46"	"268.10"	"2.42"	"1"	"1"	""	""	""	"Pf15423"	"114984"	"ENSG00000162076"	"FLYWCH2"	"hsa:114984; Q96CP2"	""	""	"0"	"0"	"20.7"	"11.9"	"17.9"	"15.9"	"20.4"	"21.1"	"31.7"	"31.9"	"32.4"	"39.4"	"66.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3C4"	"EKC/KEOPS complex subunit TPRKB OS=Homo sapiens OX=9606 GN=TPRKB PE=1 SV=1"	"4"	"1"	"2"	"1"	"175"	"19.6"	"6.79"	"311.95"	"2.41"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf08617"	"51002"	"ENSG00000144034"	"TPRKB"	"D6W5H6; hsa:51002; Q8IWR6; Q8IWR7; Q9H3K4; Q9Y3C4"	""	"tRNA modification in the nucleus and cytosol"	"1"	"0"	"48.5"	"32.8"	"51.8"	"48.2"	"53.0"	"59.1"	"192.8"	"162.2"	"112.7"	"188.1"	"241.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12891"	"Hyaluronidase-2 OS=Homo sapiens OX=9606 GN=HYAL2 PE=1 SV=4"	"4"	"1"	"1"	"1"	"473"	"53.8"	"8.19"	""	"2.41"	""	"1"	"cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf01630"	"8692"	"ENSG00000068001"	"HYAL2"	"B3KRZ2; hsa:8692; O15177; Q12891; Q9BW29"	"Glycosaminoglycan degradation"	"Hyaluronan uptake and degradation"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09038"	"Fibroblast growth factor 2 OS=Homo sapiens OX=9606 GN=FGF2 PE=1 SV=3"	"3"	"1"	"2"	"1"	"288"	"30.8"	"11.18"	"253.87"	"2.41"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00167"	"2247"	"ENSG00000138685"	"FGF2"	"A4LBB8; hsa:2247; O00527; P09038; P78443; Q16443; Q5PY50; Q7KZ11; Q7KZ72; Q9UC54; Q9UCS5; Q9UCS6"	"Angiogenesis; MicroRNAs in cardiomyocyte hypertrophy; Neural crest differentiation; Cardiac progenitor differentiation; Cardiac hypertrophic response; Pluripotent stem cell differentiation pathway; MECP2 and associated Rett syndrome; Lung fibrosis; MAPK signaling pathway; Embryonic stem cell pluripotency pathways; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Endometrial cancer; PI3K-Akt signaling pathway; Breast cancer pathway; Endochondral ossification; Osteoblast differentiation and related diseases; EGFR tyrosine kinase inhibitor resistance; Endochondral ossification with skeletal dysplasias; Neuroinflammation and glutamatergic signaling; Pleural mesothelioma; CCL18 signaling pathway; Regulation of actin cytoskeleton; DYRK1A involvement regarding cell proliferation in brain development; 4p16.3 copy number variation"	"RAF/MAP kinase cascade; Signaling by FGFR1 in disease; SHC-mediated cascade:FGFR1; FRS-mediated FGFR1 signaling; SHC-mediated cascade:FGFR2; FRS-mediated FGFR2 signaling; Signaling by FGFR2 in disease; SHC-mediated cascade:FGFR3; FRS-mediated FGFR3 signaling; FRS-mediated FGFR4 signaling; SHC-mediated cascade:FGFR4; Signaling by FGFR3 in disease; PIP3 activates AKT signaling; Constitutive Signaling by Aberrant PI3K in Cancer; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; PI3K Cascade; Interleukin-4 and Interleukin-13 signaling; Syndecan interactions; Signaling by FGFR2 IIIa TM; FGFR1b ligand binding and activation; FGFR2b ligand binding and activation; Activated point mutants of FGFR2; Phospholipase C-mediated cascade: FGFR1; Phospholipase C-mediated cascade; FGFR2; PI-3K cascade:FGFR1; PI-3K cascade:FGFR2; Negative regulation of FGFR1 signaling; Negative regulation of FGFR2 signaling; FGFRL1 modulation of FGFR1 signaling; Signaling by activated point mutants of FGFR3; FGFR4 ligand binding and activation; FGFR3c ligand binding and activation; FGFR2c ligand binding and activation; Phospholipase C-mediated cascade; FGFR3; Phospholipase C-mediated cascade; FGFR4; PI-3K cascade:FGFR3; PI-3K cascade:FGFR4; Negative regulation of FGFR3 signaling; Negative regulation of FGFR4 signaling; Signaling by activated point mutants of FGFR1; FGFR1c ligand binding and activation; POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation; Formation of intermediate mesoderm"	"69"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UI30"	"Multifunctional methyltransferase subunit TRM112-like protein OS=Homo sapiens OX=9606 GN=TRMT112 PE=1 SV=1"	"6"	"1"	"1"	"1"	"125"	"14.2"	"5.26"	""	"2.41"	""	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf03966"	"51504"	"ENSG00000173113"	"TRMT112"	"B2R539; hsa:51504; J3KNG5; Q3MHC7; Q8N2Z4; Q9UI30"	""	"Eukaryotic Translation Termination; rRNA modification in the nucleus and cytosol; tRNA modification in the nucleus and cytosol; Methylation"	"4"	"0"	"80.5"	"50.5"	"73.7"	"80.3"	"73.8"	"74.6"	"157.3"	"161.6"	"120.9"	"151.9"	"202.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11274"	"Breakpoint cluster region protein OS=Homo sapiens OX=9606 GN=BCR PE=1 SV=2"	"1"	"1"	"2"	"1"	"1271"	"142.7"	"7.03"	"246.09"	"2.41"	"1"	"1"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00168, Pf00620, Pf00621, Pf09036, Pf19057"	"613"	"ENSG00000186716"	"BCR"	"hsa:613; P11274; P78501; Q12842; Q4LE80; Q6NZI3"	"Imatinib and chronic myeloid leukemia; Extrafollicular and follicular B cell activation by SARS-CoV-2"	"RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOB GTPase cycle; Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease"	"11"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95721"	"Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29 PE=1 SV=1"	"4"	"1"	"2"	"1"	"258"	"29.0"	"5.81"	"301.86"	"2.40"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	""	"9342"	"ENSG00000099940"	"SNAP29"	"hsa:9342; O95721"	"Ciliary landscape; 22q11.2 copy number variation syndrome"	"Intra-Golgi traffic; Neutrophil degranulation"	"4"	"0"	"9.0"	"4.6"	"6.1"	"5.9"	"3.9"	"7.8"	"22.9"	"18.3"	"10.8"	"21.1"	"22.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P56381"	"ATP synthase subunit epsilon, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1E PE=1 SV=2"	"16"	"1"	"2"	"1"	"51"	"5.8"	"9.92"	"292.15"	"2.40"	"1"	"1"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf04627"	"514"	"ENSG00000124172"	"ATP5F1E"	"B2RDD0; E1P5H6; hsa:514; P56381; Q53XU6"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"5"	"0"	"107.0"	"62.2"	"70.7"	"88.4"	"82.1"	"106.3"	"153.9"	"148.5"	"119.0"	"192.2"	"220.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q67FW5"	"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 OS=Homo sapiens OX=9606 GN=B3GNTL1 PE=2 SV=2"	"3"	"1"	"1"	"1"	"361"	"40.7"	"7.40"	""	"2.40"	""	"1"	""	""	"other molecular function"	"Pf00535"	"146712"	"ENSG00000175711; ENSG00000277033"	"B3GNTL1"	"hsa:146712; Q67FW5; Q6GV30; Q8WUT3"	""	"O-linked glycosylation of mucins"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96GI7"	"Protein FAM89A OS=Homo sapiens OX=9606 GN=FAM89A PE=1 SV=1"	"10"	"1"	"1"	"1"	"184"	"19.6"	"5.92"	""	"2.40"	""	"1"	""	""	""	""	"375061"	"ENSG00000182118"	"FAM89A"	"hsa:375061; Q96GI7"	""	""	"0"	"0"	"6.0"	"4.3"	"6.9"	"4.2"	"5.6"	"4.8"	"10.2"	"15.9"	"19.8"	"16.9"	"23.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2X3"	"Nucleolar protein 58 OS=Homo sapiens OX=9606 GN=NOP58 PE=1 SV=1"	"3"	"1"	"1"	"1"	"529"	"59.5"	"8.92"	""	"2.40"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01798, Pf08156"	"51602"	"ENSG00000055044"	"NOP58"	"hsa:51602; Q53SA4; Q6PK08; Q9P036; Q9UFN3; Q9Y2X3"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; SUMOylation of RNA binding proteins; rRNA modification in the nucleus and cytosol"	"3"	"0"	"7.3"	"4.8"	"11.8"	"11.9"	"8.6"	"8.6"	"19.1"	"9.8"	"10.3"	"16.5"	"65.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18206"	"Vinculin OS=Homo sapiens OX=9606 GN=VCL PE=1 SV=4"	"1"	"1"	"2"	"1"	"1134"	"123.7"	"5.66"	"278.98"	"2.39"	"1"	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01044"	"7414"	"ENSG00000035403"	"VCL"	"hsa:7414; P18206; Q16450; Q5SWX2; Q7Z3B8; Q8IXU7"	"Integrin-mediated cell adhesion; Primary focal segmental glomerulosclerosis (FSGS); Focal adhesion; VEGFA-VEGFR2 signaling; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Melanoma; Regulation of actin cytoskeleton"	"Neutrophil degranulation; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Platelet degranulation ; Signaling by BRAF and RAF1 fusions; Signaling by ALK fusions and activated point mutants; Smooth Muscle Contraction; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants"	"18"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WVD3"	"E3 ubiquitin-protein ligase RNF138 OS=Homo sapiens OX=9606 GN=RNF138 PE=1 SV=1"	"4"	"1"	"2"	"1"	"245"	"28.2"	"6.93"	"304.81"	"2.39"	"1"	"1"	"cell-cell signaling;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05605, Pf13923, Pf18574"	"51444"	"ENSG00000134758"	"RNF138"	"B2RE17; hsa:51444; Q8WVD3; Q9H8K2; Q9UF87; Q9UKI6"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	"26.6"	"19.0"	"33.4"	"31.4"	"38.7"	"41.3"	"79.5"	"94.2"	"105.7"	"176.4"	"161.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UER7"	"Death domain-associated protein 6 OS=Homo sapiens OX=9606 GN=DAXX PE=1 SV=2"	"3"	"1"	"2"	"1"	"740"	"81.3"	"4.87"	"284.33"	"2.39"	"1"	"1"	"cell organization and biogenesis;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf03344"	"1616"	"ENSG00000204209; ENSG00000206206; ENSG00000206279; ENSG00000227046; ENSG00000231617"	"DAXX"	"B4E1I3; F5ANJ6; F5ANJ7; F5H082; hsa:1616; O14747; O15141; O15208; Q5STK9; Q9BWI3; Q9UER7"	"Androgen receptor signaling pathway; Amyotrophic lateral sclerosis (ALS); Fas ligand pathway and stress induction of heat shock proteins; MAPK signaling pathway; p38 MAPK signaling pathway"	"HCMV Early Events; SUMOylation of transcription cofactors; Inhibition of DNA recombination at telomere; Regulation of TP53 Degradation; Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations; Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations"	"11"	"0"	"8.3"	"5.1"	"15.5"	"10.7"	"13.5"	"15.0"	"21.6"	"19.5"	"13.9"	"23.3"	"27.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BPZ3"	"Polyadenylate-binding protein-interacting protein 2 OS=Homo sapiens OX=9606 GN=PAIP2 PE=1 SV=1"	"6"	"1"	"2"	"1"	"127"	"15.0"	"4.12"	"273.41"	"2.39"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf07145"	"51247"	"ENSG00000120727"	"PAIP2"	"B2RBI1; D3DQC6; hsa:51247; Q49A06; Q9BPZ3; Q9H0Y5; Q9P0Q8"	""	""	"0"	"0"	"92.6"	"49.4"	"59.8"	"71.8"	"61.1"	"75.0"	"235.6"	"234.6"	"180.5"	"234.9"	"322.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00186"	"Syntaxin-binding protein 3 OS=Homo sapiens OX=9606 GN=STXBP3 PE=1 SV=2"	"2"	"1"	"2"	"1"	"592"	"67.7"	"7.80"	"251.05"	"2.39"	"1"	"1"	"cell adhesion;cell-cell signaling;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00995"	"6814"	"ENSG00000116266"	"STXBP3"	"A8K269; A8K5K7; hsa:6814; O00186; Q53FW1; Q86YJ3; Q9UPD7"	"Insulin signaling"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Disinhibition of SNARE formation"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06280"	"Alpha-galactosidase A OS=Homo sapiens OX=9606 GN=GLA PE=1 SV=1"	"4"	"1"	"1"	"1"	"429"	"48.7"	"5.60"	""	"2.38"	""	"1"	"other metabolic processes;other biological processes"	"non-structural extracellular;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf16499, Pf17450"	"2717"	"ENSG00000102393"	"GLA"	"hsa:2717; P06280; Q6LER7"	"Degradation pathway of sphingolipids, including diseases; Ciliary landscape"	"Neutrophil degranulation; Glycosphingolipid metabolism"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P16615"	"Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2A2 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1042"	"114.7"	"5.34"	"294.82"	"2.38"	"1"	"1"	"cell adhesion;cell organization and biogenesis;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"transporter activity;other molecular function"	"Pf00122, Pf00689, Pf00690, Pf08282, Pf13246"	"488"	"ENSG00000174437"	"ATP2A2"	"A6NDN7; B4DF05; hsa:488; P16614; P16615; Q86VJ2"	"Alzheimer's disease and miRNA effects; Arrhythmogenic right ventricular cardiomyopathy; Endothelin pathways; Myometrial relaxation and contraction pathways; Alzheimer's disease; Calcium regulation in cardiac cells"	"Ion homeostasis; Ion transport by P-type ATPases; Pre-NOTCH Processing in Golgi; Reduction of cytosolic Ca++ levels"	"10"	"0"	"23.1"	"14.9"	"24.5"	"20.0"	"23.0"	"29.0"	"40.5"	"31.9"	"21.0"	"49.4"	"65.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRX2"	"39S ribosomal protein L17, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL17 PE=1 SV=1"	"5"	"1"	"2"	"1"	"175"	"20.0"	"10.11"	"244.81"	"2.38"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf01196"	"63875"	"ENSG00000158042"	"MRPL17"	"D3DQU3; hsa:63875; Q6IAH8; Q96Q53; Q9C066; Q9NRX2"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"31.9"	"24.5"	"28.9"	"34.5"	"38.7"	"32.6"	"69.6"	"62.8"	"49.8"	"65.0"	"70.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4F1"	"FERM, ARHGEF and pleckstrin domain-containing protein 1 OS=Homo sapiens OX=9606 GN=FARP1 PE=1 SV=1"	"2"	"2"	"3"	"2"	"1045"	"118.6"	"8.15"	"563.34"	"2.38"	"2"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00169, Pf00373, Pf00621, Pf08736, Pf09379, Pf09380"	"10160"	"ENSG00000152767"	"FARP1"	"hsa:10160; Q5JVI9; Q6IQ29; Q9Y4F1"	""	"RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOF GTPase cycle"	"4"	"0"	"25.8"	"15.1"	"27.0"	"27.4"	"27.2"	"21.4"	"46.5"	"40.5"	"33.9"	"46.9"	"67.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95163"	"Elongator complex protein 1 OS=Homo sapiens OX=9606 GN=ELP1 PE=1 SV=3"	"1"	"2"	"3"	"2"	"1332"	"150.2"	"5.94"	"616.28"	"2.38"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04762"	"8518"	"ENSG00000070061"	"ELP1"	"hsa:8518; O95163; Q5JSV2; Q9H327; Q9UG87"	""	"HATs acetylate histones"	"1"	"0"	"22.5"	"14.2"	"18.8"	"14.8"	"20.3"	"17.4"	"30.7"	"26.4"	"15.9"	"33.4"	"48.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WU90"	"Zinc finger CCCH domain-containing protein 15 OS=Homo sapiens OX=9606 GN=ZC3H15 PE=1 SV=1"	"2"	"1"	"1"	"1"	"426"	"48.6"	"5.31"	""	"2.37"	""	"1"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00642, Pf16543"	"55854"	"ENSG00000065548"	"ZC3H15"	"B4DMW2; D3DPG7; hsa:55854; Q5QTQ4; Q8WU90; Q8WZ06; Q9NUZ3; Q9NZ37; Q9P079"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14839"	"Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2"	"0"	"1"	"2"	"1"	"1912"	"217.9"	"5.86"	"250.22"	"2.36"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf00385, Pf00628, Pf06461, Pf06465, Pf08073, Pf08074"	"1108"	"ENSG00000111642"	"CHD4"	"hsa:1108; Q14839; Q8IXZ5"	"Rett syndrome causing genes; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"RNA Polymerase I Transcription Initiation; Potential therapeutics for SARS; HDACs deacetylate histones; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of PTEN gene transcription; Regulation of TP53 Activity through Acetylation; NGF-stimulated transcription"	"9"	"0"	"20.5"	"15.7"	"21.3"	"24.0"	"19.6"	"33.5"	"37.1"	"37.3"	"30.0"	"43.4"	"45.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75794"	"Cell division cycle protein 123 homolog OS=Homo sapiens OX=9606 GN=CDC123 PE=1 SV=1"	"3"	"1"	"2"	"1"	"336"	"39.1"	"4.81"	"243.52"	"2.36"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"other cell component"	""	"Pf07065"	"8872"	"ENSG00000151465"	"CDC123"	"A8JZZ7; hsa:8872; O75794; Q14107; Q5T0L4; Q5T0L5; Q5T0L7; Q5T0L8; Q5T0L9"	""	""	"0"	"0"	"6.7"	"3.0"	"6.2"	"6.2"	"9.0"	"8.3"	"12.1"	"18.3"	"8.0"	"15.4"	"28.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HC38"	"Glyoxalase domain-containing protein 4 OS=Homo sapiens OX=9606 GN=GLOD4 PE=1 SV=1"	"4"	"1"	"1"	"1"	"313"	"34.8"	"5.60"	""	"2.36"	""	"1"	""	"mitochondrion"	""	""	"51031"	"ENSG00000167699"	"GLOD4"	"D3DTG9; D3DTH1; hsa:51031; Q96B89; Q9H3J8; Q9HC37; Q9HC38; Q9NVN1"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14966"	"Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1978"	"220.5"	"6.38"	"271.51"	"2.35"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf12171"	"27332"	"ENSG00000075292"	"ZNF638"	"A0A096LPH6; B5MDV1; B7ZLD1; hsa:27332; Q14966; Q53R34; Q5XJ05; Q68DP3; Q6P2H2; Q7Z3T7; Q8NF92; Q8TCA1; Q9H2G1; Q9NP37"	""	"Transcriptional regulation of white adipocyte differentiation"	"1"	"0"	"13.2"	"4.4"	"7.8"	"7.2"	"5.4"	"10.9"	"14.5"	"10.5"	"12.2"	"22.2"	"23.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P1F3"	"Costars family protein ABRACL OS=Homo sapiens OX=9606 GN=ABRACL PE=1 SV=1"	"16"	"1"	"2"	"1"	"81"	"9.1"	"6.29"	"252.24"	"2.35"	"1"	"1"	"other biological processes"	""	""	"Pf14705"	"58527"	"ENSG00000146386"	"ABRACL"	"hsa:58527; Q5SZC8; Q9P0A1; Q9P1F3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14974"	"Protein phosphatase 1 regulatory subunit 12A OS=Homo sapiens OX=9606 GN=PPP1R12A PE=1 SV=1"	"1"	"1"	"2"	"1"	"1030"	"115.2"	"5.40"	"267.65"	"2.35"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00023, Pf15898"	"4659"	"ENSG00000058272"	"PPP1R12A"	"B4DZ09; F8VWB4; hsa:4659; O14974; Q2NKL4; Q569H0; Q86WU3; Q8NFR6; Q9BYH0"	"Focal adhesion; Hippo-Merlin signaling dysregulation; Regulation of actin cytoskeleton"	"Regulation of PLK1 Activity at G2/M Transition; RHO GTPases activate CIT; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; RHO GTPases activate PAKs"	"8"	"0"	"51.4"	"24.6"	"40.1"	"49.5"	"47.6"	"51.0"	"102.2"	"94.1"	"64.8"	"91.1"	"163.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NXE8"	"Pre-mRNA-splicing factor CWC25 homolog OS=Homo sapiens OX=9606 GN=CWC25 PE=1 SV=1"	"2"	"1"	"2"	"1"	"425"	"49.6"	"10.18"	"276.75"	"2.35"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf10197, Pf12542"	"54883"	"ENSG00000273559; ENSG00000276761"	"CWC25"	"A0JLM3; hsa:54883; Q68DK5; Q9NXE8"	"17q12 copy number variation syndrome"	"mRNA Splicing - Major Pathway"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VVW2"	"GTPase-activating Rap/Ran-GAP domain-like protein 3 OS=Homo sapiens OX=9606 GN=GARNL3 PE=2 SV=2"	"1"	"1"	"1"	"1"	"1013"	"112.8"	"7.65"	""	"2.35"	""	"1"	"other biological processes"	"other cell component"	"enzyme regulator activity"	"Pf00780, Pf02145"	"84253"	"ENSG00000136895"	"GARNL3"	"B4DEP7; B7Z3Q6; hsa:84253; Q5VVW2; Q8IYU1; Q8N951; Q8ND89; Q9BQH6"	""	""	"0"	"0"	"34.2"	"27.9"	"40.5"	"36.3"	"34.5"	"33.9"	"87.7"	"100.3"	"95.9"	"180.8"	"415.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43847"	"Nardilysin OS=Homo sapiens OX=9606 GN=NRDC PE=1 SV=3"	"1"	"1"	"1"	"1"	"1151"	"131.6"	"4.98"	""	"2.35"	""	"1"	"protein metabolism;other biological processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00675, Pf05193, Pf16187"	"4898"	"ENSG00000078618"	"NRDC"	"A6NI41; hsa:4898; O15241; O15242; O43847; Q5VUL0; Q96HB2; Q9NU57"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQA1"	"Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1"	"2"	"1"	"1"	"1"	"342"	"36.7"	"5.17"	""	"2.35"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400"	"79084"	"ENSG00000116455"	"WDR77"	"B3KMW6; B4DP38; hsa:79084; Q3LID2; Q53FU2; Q6JZZ5; Q96GK4; Q9BQA1; Q9BWY3"	""	"RMTs methylate histone arginines; snRNP Assembly"	"2"	"0"	"33.3"	"26.8"	"47.9"	"28.5"	"37.5"	"34.7"	"52.0"	"51.6"	"38.0"	"48.1"	"72.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43583"	"Density-regulated protein OS=Homo sapiens OX=9606 GN=DENR PE=1 SV=2"	"4"	"1"	"2"	"1"	"198"	"22.1"	"5.30"	"242.79"	"2.35"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	""	"nucleic acid binding activity"	"Pf01253"	"8562"	"ENSG00000139726"	"DENR"	"hsa:8562; O43583; Q9H3U6; Q9UKZ0"	""	""	"0"	"0"	"84.1"	"53.0"	"71.4"	"73.6"	"70.9"	"92.4"	"307.3"	"302.1"	"244.8"	"341.4"	"512.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z4H3"	"5'-deoxynucleotidase HDDC2 OS=Homo sapiens OX=9606 GN=HDDC2 PE=1 SV=1"	"8"	"1"	"1"	"1"	"204"	"23.4"	"5.49"	""	"2.35"	""	"1"	""	""	"other molecular function"	"Pf13023"	"51020"	"ENSG00000111906"	"HDDC2"	"hsa:51020; Q5TDQ4; Q6NZ49; Q7Z4H3; Q9BTT2; Q9BV31; Q9Y3D1"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06737"	"Glycogen phosphorylase, liver form OS=Homo sapiens OX=9606 GN=PYGL PE=1 SV=4"	"1"	"1"	"2"	"1"	"847"	"97.1"	"7.17"	"239.59"	"2.34"	"1"	"1"	"other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;other cell component"	"other molecular function"	"Pf00343"	"5836"	"ENSG00000100504"	"PYGL"	"A6NDQ4; B4DUB7; F5H816; hsa:5836; O60567; O60752; O60913; P06737; Q501V9; Q641R5; Q96G82"	"TNF-alpha signaling pathway; Glycogen synthesis and degradation; Disorders of galactose metabolism"	"Neutrophil degranulation; Glycogen breakdown (glycogenolysis)"	"5"	"0"	"14.5"	"11.4"	"18.5"	"17.2"	"16.7"	"15.6"	"30.6"	"24.8"	"18.0"	"36.8"	"49.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75151"	"Lysine-specific demethylase PHF2 OS=Homo sapiens OX=9606 GN=PHF2 PE=1 SV=4"	"1"	"1"	"2"	"1"	"1096"	"120.7"	"9.17"	"288.25"	"2.34"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00628, Pf02373, Pf17811"	"5253"	"ENSG00000197724"	"PHF2"	"hsa:5253; O75151; Q4VXG0; Q8N3K2; Q9Y6N4"	""	"HDMs demethylate histones"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q969E8"	"Pre-rRNA-processing protein TSR2 homolog OS=Homo sapiens OX=9606 GN=TSR2 PE=1 SV=1"	"4"	"1"	"2"	"1"	"191"	"20.9"	"4.39"	"287.78"	"2.34"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf10273"	"90121"	"ENSG00000158526"	"TSR2"	"hsa:90121; Q969E8"	""	""	"0"	"0"	"56.5"	"37.4"	"47.2"	"39.5"	"36.5"	"54.2"	"82.7"	"78.3"	"48.4"	"84.0"	"110.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NEZ5"	"F-box only protein 22 OS=Homo sapiens OX=9606 GN=FBXO22 PE=1 SV=1"	"2"	"1"	"2"	"1"	"403"	"44.5"	"7.03"	"277.53"	"2.34"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"cytosol;cytoskeleton;nucleus"	"other molecular function"	"Pf00646, Pf10442"	"26263"	"ENSG00000167196"	"FBXO22"	"hsa:26263; Q0D2P8; Q6PIL5; Q8IXW3; Q8NEZ5; Q9H824; Q9UKC0"	""	"Antigen processing: Ubiquitination & Proteasome degradation; Neddylation"	"2"	"0"	"39.7"	"33.7"	"47.5"	"33.5"	"41.4"	"40.7"	"61.3"	"47.2"	"47.5"	"53.2"	"65.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UH65"	"Switch-associated protein 70 OS=Homo sapiens OX=9606 GN=SWAP70 PE=1 SV=1"	"2"	"1"	"2"	"1"	"585"	"69.0"	"5.87"	"342.71"	"2.34"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00169"	"23075"	"ENSG00000133789"	"SWAP70"	"D3DQV1; hsa:23075; O75135; Q7LCY6; Q9P061; Q9P0Z8; Q9UH65"	""	"RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43464"	"Serine protease HTRA2, mitochondrial OS=Homo sapiens OX=9606 GN=HTRA2 PE=1 SV=2"	"2"	"1"	"2"	"1"	"458"	"48.8"	"10.07"	"264.37"	"2.34"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf02163, Pf13365, Pf17820"	"27429"	"ENSG00000115317"	"HTRA2"	"hsa:27429; O43464; Q9HBZ4; Q9P0Y3; Q9P0Y4"	"Apoptosis modulation and signaling; Parkinson's disease pathway; Nanomaterial induced apoptosis; Ciliary landscape; Complement system in neuronal development and plasticity"	""	"5"	"0"	"44.3"	"28.7"	"37.3"	"35.3"	"34.3"	"42.7"	"58.8"	"52.0"	"42.5"	"59.0"	"92.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y512"	"Sorting and assembly machinery component 50 homolog OS=Homo sapiens OX=9606 GN=SAMM50 PE=1 SV=3"	"4"	"2"	"2"	"2"	"469"	"51.9"	"6.90"	"252.97"	"2.33"	"1"	"1"	"cell organization and biogenesis;transport"	"other membranes;mitochondrion"	""	"Pf01103"	"25813"	"ENSG00000100347"	"SAMM50"	"hsa:25813; Q53HC4; Q56VW7; Q969Y9; Q96I46; Q9NW85; Q9UQM9; Q9Y512"	""	"Mitochondrial protein import; RAC2 GTPase cycle; Cristae formation"	"3"	"0"	"286.4"	"157.3"	"243.1"	"193.3"	"260.0"	"249.3"	"386.7"	"339.4"	"225.4"	"406.4"	"552.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TEM1"	"Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3"	"1"	"1"	"2"	"1"	"1887"	"205.0"	"6.81"	"275.65"	"2.33"	"1"	"1"	"transport"	"other membranes;ER/Golgi;nucleus"	""	"Pf02368"	"23225"	"ENSG00000132182"	"NUP210"	"A6NN56; hsa:23225; O94980; Q6NXG6; Q8NBJ1; Q8TEM1; Q9H6C8; Q9UFP3"	""	"SUMOylation of DNA damage response and repair proteins; Vpr-mediated nuclear import of PICs; SARS-CoV-2 activates/modulates innate and adaptive immune responses; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; snRNP Assembly; Regulation of HSF1-mediated heat shock response; SUMOylation of chromatin organization proteins; HCMV Late Events; HCMV Early Events; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus"	"28"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H0A0"	"RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2"	"3"	"1"	"1"	"1"	"1025"	"115.7"	"8.27"	""	"2.33"	""	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05127, Pf08351, Pf13718, Pf13725"	"55226"	"ENSG00000135372"	"NAT10"	"B4DFD5; E7ESU4; E9PMN9; hsa:55226; Q86WK5; Q9C0F4; Q9H0A0; Q9HA61; Q9NVF2"	"Metapathway biotransformation Phase I and II"	"rRNA modification in the nucleus and cytosol"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P1L8"	"39S ribosomal protein L14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL14 PE=1 SV=1"	"6"	"1"	"1"	"1"	"145"	"15.9"	"10.24"	""	"2.33"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00238"	"64928"	"ENSG00000180992"	"MRPL14"	"B2R575; hsa:64928; Q6P1L8; Q96Q72"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"12.7"	"9.1"	"18.1"	"13.3"	"10.8"	"14.3"	"25.7"	"26.5"	"24.4"	"32.1"	"50.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60547"	"GDP-mannose 4,6 dehydratase OS=Homo sapiens OX=9606 GN=GMDS PE=1 SV=1"	"8"	"2"	"3"	"2"	"372"	"41.9"	"7.31"	"514.26"	"2.33"	"2"	"1"	"other metabolic processes;signal transduction"	"cytosol;other cell component"	"other molecular function"	"Pf16363"	"2762"	"ENSG00000112699"	"GMDS"	"E9PI88; hsa:2762; O60547; O75357; Q5T954; Q6FH09; Q9UGZ3; Q9UJK9"	""	"GDP-fucose biosynthesis"	"1"	"0"	"62.6"	"47.2"	"74.2"	"62.4"	"78.2"	"89.0"	"99.7"	"100.0"	"80.9"	"100.9"	"163.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13601"	"KRR1 small subunit processome component homolog OS=Homo sapiens OX=9606 GN=KRR1 PE=1 SV=4"	"5"	"2"	"3"	"2"	"381"	"43.6"	"9.77"	"859.97"	"2.33"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf17903"	"11103"	"ENSG00000111615"	"KRR1"	"A0FIK6; A0JLP0; B2R989; E7EUQ0; hsa:11103; Q13601; Q8NEA8; Q8TC37; Q96AT5"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"120.9"	"63.5"	"81.9"	"89.7"	"93.5"	"82.6"	"495.9"	"477.2"	"379.8"	"617.0"	"908.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H446"	"RWD domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RWDD1 PE=1 SV=1"	"5"	"1"	"2"	"1"	"243"	"27.9"	"4.20"	"342.52"	"2.32"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"other cell component"	""	"Pf05773"	"51389"	"ENSG00000111832"	"RWDD1"	"A8K3W2; A8MT24; hsa:51389; Q9H446; Q9Y313; Q9Y6B3"	""	""	"0"	"0"	"22.3"	"14.8"	"18.6"	"19.5"	"22.3"	"20.0"	"78.7"	"68.2"	"44.6"	"69.7"	"84.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92558"	"Wiskott-Aldrich syndrome protein family member 1 OS=Homo sapiens OX=9606 GN=WASF1 PE=1 SV=1"	"2"	"1"	"1"	"1"	"559"	"61.6"	"6.46"	""	"2.32"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02205"	"8936"	"ENSG00000112290"	"WASF1"	"E1P5F2; hsa:8936; Q5SZK7; Q92558"	"VEGFA-VEGFR2 signaling; Regulation of actin cytoskeleton"	"VEGFA-VEGFR2 Pathway; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RAC1 GTPase cycle; RHO GTPases Activate WASPs and WAVEs; RAC3 GTPase cycle"	"8"	"0"	"6.4"	"3.5"	"5.5"	"5.5"	"6.6"	"5.7"	"20.0"	"16.5"	"15.1"	"24.8"	"38.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H0S4"	"Probable ATP-dependent RNA helicase DDX47 OS=Homo sapiens OX=9606 GN=DDX47 PE=1 SV=1"	"3"	"1"	"2"	"1"	"455"	"50.6"	"9.10"	"248.18"	"2.32"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;signal transduction"	"nucleus"	"other molecular function"	"Pf00270, Pf00271"	"51202"	"ENSG00000213782"	"DDX47"	"B3KXP4; G5E955; hsa:51202; Q96GM0; Q96NV8; Q9H0S4; Q9UI98"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"6.3"	"7.0"	"5.8"	"11.6"	"10.7"	"10.5"	"16.5"	"21.8"	"15.7"	"23.0"	"16.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UN86"	"Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2"	"3"	"2"	"3"	"1"	"482"	"54.1"	"5.55"	"522.77"	"2.32"	"2"	"1"	"cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf02136"	"9908"	"ENSG00000138757"	"G3BP2"	"A8K6X1; hsa:9908; O60606; O75149; Q9UN86; Q9UPA1"	""	"SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"1"	"0"	"16.1"	"15.3"	"21.5"	"17.2"	"23.7"	"22.8"	"56.4"	"56.9"	"52.9"	"46.9"	"69.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9GZR7"	"ATP-dependent RNA helicase DDX24 OS=Homo sapiens OX=9606 GN=DDX24 PE=1 SV=1"	"1"	"1"	"2"	"1"	"859"	"96.3"	"9.06"	"297.36"	"2.31"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00270, Pf00271"	"57062"	"ENSG00000089737; ENSG00000273761"	"DDX24"	"E7EMJ4; hsa:57062; Q4V9L5; Q9GZR7"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02224"	"Centromere-associated protein E OS=Homo sapiens OX=9606 GN=CENPE PE=1 SV=2"	"0"	"1"	"1"	"1"	"2701"	"316.2"	"5.64"	""	"2.31"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225"	"1062"	"ENSG00000138778"	"CENPE"	"A6NKY9; A8K2U7; hsa:1062; Q02224; Q4LE75"	"Regulation of sister chromatid separation at the metaphase-anaphase transition"	"COPI-dependent Golgi-to-ER retrograde traffic; MHC class II antigen presentation; Kinesins; RHO GTPases Activate Formins; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"10"	"0"	"86.1"	"32.4"	"64.7"	"55.9"	"52.1"	"54.2"	"88.6"	"73.8"	"49.8"	"88.1"	"130.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NW13"	"RNA-binding protein 28 OS=Homo sapiens OX=9606 GN=RBM28 PE=1 SV=3"	"1"	"1"	"2"	"1"	"759"	"85.7"	"9.22"	"257.34"	"2.31"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf00076"	"55131"	"ENSG00000106344"	"RBM28"	"A4D100; B4DU52; E9PDD9; hsa:55131; Q53H65; Q96CV3; Q9NW13"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"10.9"	"9.2"	"9.1"	"14.7"	"10.0"	"11.8"	"36.6"	"41.8"	"30.0"	"47.2"	"53.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3C1"	"Nucleolar protein 16 OS=Homo sapiens OX=9606 GN=NOP16 PE=1 SV=2"	"19"	"2"	"2"	"2"	"178"	"21.2"	"9.94"	"384.51"	"2.31"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	""	"Pf09420"	"51491"	"ENSG00000048162"	"NOP16"	"B4DV13; D6RGD3; hsa:51491; Q05D05; Q6IAI6; Q6PIM0; Q8IXL5; Q9Y3C1"	"5q35 copy number variation"	""	"1"	"0"	"8.6"	"3.9"	"8.5"	"8.5"	"10.6"	"10.8"	"31.3"	"27.0"	"17.5"	"49.0"	"81.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5PRF9"	"Protein Smaug homolog 2 OS=Homo sapiens OX=9606 GN=SAMD4B PE=1 SV=1"	"2"	"1"	"2"	"1"	"694"	"75.4"	"6.83"	"282.81"	"2.31"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00536"	"55095"	"ENSG00000179134"	"SAMD4B"	"A5Z0M6; hsa:55095; Q5PRF9; Q6P194"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P161"	"39S ribosomal protein L54, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL54 PE=1 SV=1"	"7"	"1"	"2"	"1"	"138"	"15.8"	"9.60"	"271.93"	"2.31"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf08561"	"116541"	"ENSG00000183617"	"MRPL54"	"hsa:116541; Q6P161"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"90.5"	"60.6"	"138.0"	"86.1"	"72.6"	"101.7"	"226.0"	"227.5"	"182.2"	"274.2"	"336.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P68402"	"Platelet-activating factor acetylhydrolase IB subunit beta OS=Homo sapiens OX=9606 GN=PAFAH1B2 PE=1 SV=1"	"8"	"1"	"2"	"1"	"229"	"25.6"	"5.92"	"247.46"	"2.30"	"1"	"1"	"other metabolic processes;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf13472"	"5049"	"ENSG00000168092"	"PAFAH1B2"	"A8DPS5; A8DPS6; A8DPS7; E9PEJ5; E9PLP3; hsa:5049; O00687; P68402; Q29459; Q6IBR6"	"PAFAH1B1 copy number variation"	"Neutrophil degranulation; COPI-independent Golgi-to-ER retrograde traffic"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UQB8"	"Brain-specific angiogenesis inhibitor 1-associated protein 2 OS=Homo sapiens OX=9606 GN=BAIAP2 PE=1 SV=1"	"4"	"2"	"3"	"2"	"552"	"60.8"	"8.90"	"556.62"	"2.30"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf07653, Pf08397"	"10458"	"ENSG00000175866"	"BAIAP2"	"hsa:10458; O43858; Q53HB1; Q86WC1; Q8N5C0; Q96CR7; Q9UBR3; Q9UQ43; Q9UQB8"	"Regulation of actin cytoskeleton"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; CDC42 GTPase cycle; RAC1 GTPase cycle; RHO GTPases Activate WASPs and WAVEs; RAC3 GTPase cycle; VEGFA-VEGFR2 Pathway"	"8"	"0"	"16.6"	"11.9"	"12.3"	"15.0"	"12.0"	"20.8"	"36.6"	"50.4"	"36.0"	"73.3"	"100.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q969S3"	"Zinc finger protein 622 OS=Homo sapiens OX=9606 GN=ZNF622 PE=1 SV=1"	"2"	"1"	"1"	"1"	"477"	"54.2"	"6.15"	""	"2.30"	""	"1"	"signal transduction;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf12171, Pf12756"	"90441"	"ENSG00000173545"	"ZNF622"	"hsa:90441; Q969S3"	""	""	"0"	"0"	"6.7"	"0.0"	"2.8"	"4.2"	"5.0"	"6.6"	"24.0"	"21.4"	"18.5"	"24.6"	"25.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55199"	"RNA polymerase II elongation factor ELL OS=Homo sapiens OX=9606 GN=ELL PE=1 SV=1"	"2"	"1"	"2"	"1"	"621"	"68.2"	"9.33"	"266.22"	"2.29"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf07303, Pf10390"	"8178"	"ENSG00000105656"	"ELL"	"hsa:8178; P55199"	"Interactome of polycomb repressive complex 2 (PRC2)"	"Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; Transcription-Coupled Nucleotide Excision Repair (TC-NER)"	"14"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9NRN7"	"L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase OS=Homo sapiens OX=9606 GN=AASDHPPT PE=1 SV=2"	"7"	"2"	"3"	"2"	"309"	"35.8"	"6.80"	"287.40"	"2.29"	"1"	"2"	"protein metabolism;other metabolic processes"	"cytosol"	"other molecular function"	"Pf01648"	"60496"	"ENSG00000149313"	"AASDHPPT"	"B2R6D1; B4DDW7; hsa:60496; Q9C068; Q9NRN7; Q9P0Q3; Q9UG80; Q9Y389"	""	"Vitamin B5 (pantothenate) metabolism"	"1"	"0"	"46.7"	"31.6"	"46.9"	"43.1"	"43.4"	"50.8"	"64.3"	"57.4"	"52.4"	"108.4"	"138.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BT40"	"Inositol polyphosphate 5-phosphatase K OS=Homo sapiens OX=9606 GN=INPP5K PE=1 SV=3"	"4"	"2"	"2"	"2"	"448"	"51.1"	"6.54"	"310.54"	"2.29"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf03372, Pf17751"	"51763"	"ENSG00000132376"	"INPP5K"	"B2R6I2; B2R750; D3DTH8; hsa:51763; Q15733; Q9BT40; Q9NPJ5; Q9P2R5"	"Notch signaling; VEGFA-VEGFR2 signaling; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"Synthesis of PIPs at the plasma membrane"	"4"	"0"	"92.3"	"51.4"	"75.9"	"91.4"	"87.8"	"92.6"	"182.2"	"183.2"	"156.6"	"254.6"	"337.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BWD1"	"Acetyl-CoA acetyltransferase, cytosolic OS=Homo sapiens OX=9606 GN=ACAT2 PE=1 SV=2"	"4"	"2"	"3"	"2"	"397"	"41.3"	"6.92"	"530.31"	"2.29"	"2"	"1"	"other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00108, Pf02803"	"39"	"ENSG00000120437"	"ACAT2"	"B7Z233; E1P5B1; hsa:39; Q16146; Q5TCL7; Q8TDM4; Q9BWD1"	"Mevalonate pathway; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Cholesterol metabolism; Cholesterol biosynthesis pathway in hepatocytes; Enterocyte cholesterol metabolism"	"Cholesterol biosynthesis"	"6"	"0"	"108.7"	"56.1"	"72.4"	"62.3"	"57.9"	"69.2"	"94.2"	"75.7"	"69.6"	"108.0"	"188.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y570"	"Protein phosphatase methylesterase 1 OS=Homo sapiens OX=9606 GN=PPME1 PE=1 SV=3"	"3"	"1"	"1"	"1"	"386"	"42.3"	"5.97"	""	"2.29"	""	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes"	"nucleus"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf12697"	"51400"	"ENSG00000214517"	"PPME1"	"B3KMU6; B5MEE7; hsa:51400; J3QT22; Q8WYG8; Q9NVT5; Q9UI18; Q9Y570"	""	"Cyclin A/B1/B2 associated events during G2/M transition"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H9C1"	"Spermatogenesis-defective protein 39 homolog OS=Homo sapiens OX=9606 GN=VIPAS39 PE=1 SV=1"	"2"	"1"	"2"	"1"	"493"	"57.0"	"7.40"	"278.35"	"2.28"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf04840"	"63894"	"ENSG00000151445"	"VIPAS39"	"B4DPI6; hsa:63894; O95434; Q9H7E1; Q9H9C1; Q9H9I9"	""	""	"0"	"0"	"43.4"	"22.6"	"33.1"	"31.3"	"37.0"	"39.3"	"98.9"	"102.0"	"68.7"	"98.1"	"150.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q2KHT3"	"Protein CLEC16A OS=Homo sapiens OX=9606 GN=CLEC16A PE=1 SV=2"	"1"	"1"	"2"	"1"	"1053"	"117.6"	"5.86"	"238.01"	"2.28"	"1"	"1"	"other metabolic processes;stress response;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf09758, Pf19439"	"23274"	"ENSG00000038532"	"CLEC16A"	"hsa:23274; O15058; Q2KHT3; Q6ZTB2"	"Vitamin D receptor pathway"	""	"1"	"0"	"131.4"	"95.7"	"180.5"	"142.8"	"160.8"	"147.0"	"279.4"	"239.8"	"160.3"	"311.5"	"437.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BZJ0"	"Crooked neck-like protein 1 OS=Homo sapiens OX=9606 GN=CRNKL1 PE=1 SV=4"	"2"	"1"	"1"	"1"	"848"	"100.4"	"8.00"	""	"2.28"	""	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf02184"	"51340"	"ENSG00000101343"	"CRNKL1"	"A8K9T4; hsa:51340; Q5JY64; Q8WYI5; Q9BZI9; Q9BZJ0; Q9BZJ1; Q9BZJ2; Q9GZW7; Q9H8F8; Q9NQH5; Q9NYD8"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"n/a"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NP79"	"Vacuolar protein sorting-associated protein VTA1 homolog OS=Homo sapiens OX=9606 GN=VTA1 PE=1 SV=1"	"3"	"1"	"2"	"1"	"307"	"33.9"	"6.29"	"256.16"	"2.28"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	""	"Pf04652, Pf18097"	"51534"	"ENSG00000009844"	"VTA1"	"B4DW55; E1P594; E7ETQ7; hsa:51534; Q5TGM1; Q6IAE8; Q9H0R2; Q9H3K9; Q9NP79; Q9P0Q0"	""	"Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT)"	"2"	"0"	"62.4"	"47.6"	"55.3"	"45.8"	"63.8"	"63.7"	"83.2"	"85.7"	"51.5"	"104.4"	"117.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IXM3"	"39S ribosomal protein L41, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL41 PE=1 SV=1"	"5"	"1"	"1"	"1"	"137"	"15.4"	"9.57"	""	"2.28"	""	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus;other cell component"	"other molecular function"	"Pf09809"	"64975"	"ENSG00000182154"	"MRPL41"	"hsa:64975; Q8IXM3; Q96Q49"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"47.2"	"42.5"	"46.6"	"51.7"	"51.6"	"68.0"	"109.3"	"107.9"	"72.5"	"119.0"	"123.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q4LE39"	"AT-rich interactive domain-containing protein 4B OS=Homo sapiens OX=9606 GN=ARID4B PE=1 SV=2"	"2"	"2"	"3"	"2"	"1312"	"147.7"	"5.12"	"476.88"	"2.27"	"2"	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;mitochondrion;nucleus"	"nucleic acid binding activity"	"Pf01388, Pf08169, Pf11717"	"51742"	"ENSG00000054267"	"ARID4B"	"A1L465; hsa:51742; Q3MHV4; Q4LE39; Q5HY99; Q5T2C2; Q5T2C3; Q5T2C4; Q5T2C5; Q5T2C6; Q6P600; Q86UX1; Q86WR4; Q9H915; Q9NYU3; Q9NZB6; Q9NZG4; Q9P2W4; Q9UF62; Q9Y6E1"	"Pathways affected in adenoid cystic carcinoma"	"NoRC negatively regulates rRNA expression; Potential therapeutics for SARS; HDACs deacetylate histones"	"4"	"0"	"10.5"	"8.3"	"7.7"	"13.5"	"9.9"	"8.2"	"20.9"	"19.1"	"14.5"	"18.3"	"32.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42765"	"3-ketoacyl-CoA thiolase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAA2 PE=1 SV=2"	"2"	"1"	"2"	"1"	"397"	"41.9"	"8.09"	"270.07"	"2.27"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;transport"	"mitochondrion"	"other molecular function"	"Pf00108, Pf02803"	"10449"	"ENSG00000167315"	"ACAA2"	"hsa:10449; P42765; Q9BUT6"	"Fatty acid biosynthesis"	"Mitochondrial Fatty Acid Beta-Oxidation"	"2"	"0"	"25.1"	"17.7"	"27.1"	"20.5"	"24.4"	"24.2"	"59.3"	"54.7"	"60.1"	"130.3"	"214.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q06481"	"Amyloid-like protein 2 OS=Homo sapiens OX=9606 GN=APLP2 PE=1 SV=2"	"2"	"1"	"1"	"1"	"763"	"86.9"	"4.79"	""	"2.27"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00014, Pf02177, Pf10515, Pf12924, Pf12925"	"334"	"ENSG00000084234"	"APLP2"	"B3KXX9; H7BXI4; hsa:334; Q06481; Q13861; Q14594; Q14662; Q71U10; Q7M4L3; Q9BT36"	"Splicing factor NOVA regulated synaptic proteins"	"Platelet degranulation ; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VZE5"	"N-alpha-acetyltransferase 35, NatC auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA35 PE=1 SV=1"	"2"	"1"	"1"	"1"	"725"	"83.6"	"7.05"	""	"2.27"	""	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	""	"Pf04112"	"60560"	"ENSG00000135040"	"NAA35"	"hsa:60560; Q5VZE5; Q5VZE6; Q9H631; Q9H703"	""	"Retrograde transport at the Trans-Golgi-Network"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N9R8"	"Protein SCAI OS=Homo sapiens OX=9606 GN=SCAI PE=1 SV=2"	"2"	"1"	"2"	"1"	"606"	"70.4"	"8.60"	"259.88"	"2.26"	"1"	"1"	"other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf12070"	"286205"	"ENSG00000173611"	"SCAI"	"hsa:286205; Q3SXZ1; Q3SXZ2; Q5T163; Q8N1I4; Q8N9R8"	""	"RHO GTPases Activate Formins"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N5L8"	"Ribonuclease P protein subunit p25-like protein OS=Homo sapiens OX=9606 GN=RPP25L PE=1 SV=1"	"6"	"1"	"2"	"1"	"163"	"17.6"	"10.30"	"262.75"	"2.26"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf01918"	"138716"	"ENSG00000164967"	"RPP25L"	"D3DRM5; hsa:138716; Q8N5L8"	""	""	"0"	"0"	"24.7"	"13.8"	"21.0"	"22.4"	"18.5"	"13.9"	"56.6"	"48.9"	"26.5"	"44.9"	"61.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35613"	"Basigin OS=Homo sapiens OX=9606 GN=BSG PE=1 SV=2"	"4"	"2"	"3"	"2"	"385"	"42.2"	"5.66"	"505.59"	"2.25"	"2"	"1"	"developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf13927"	"682"	"ENSG00000172270"	"BSG"	"A6NJW1; D3YLG5; hsa:682; P35613; Q7Z796; Q8IZL7"	"Matrix metalloproteinases; VEGFA-VEGFR2 signaling; IL-18 signaling pathway"	"Degradation of the extracellular matrix; Integrin cell surface interactions; Pyruvate metabolism; Aspirin ADME; Basigin interactions; Proton-coupled monocarboxylate transport; Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT)"	"10"	"0"	"359.0"	"205.9"	"220.1"	"149.7"	"243.0"	"253.7"	"333.9"	"235.2"	"200.3"	"426.5"	"505.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N983"	"39S ribosomal protein L43, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL43 PE=1 SV=1"	"6"	"1"	"2"	"1"	"215"	"23.4"	"8.65"	"240.72"	"2.25"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf05047"	"84545"	"ENSG00000055950"	"MRPL43"	"B1AL06; B1AL07; B1AL09; B1AL10; C9J5Q3; D3DR71; hsa:84545; Q5JW06; Q7Z719; Q7Z7H6; Q86XN1; Q8N983; Q9BYC7"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P40925"	"Malate dehydrogenase, cytoplasmic OS=Homo sapiens OX=9606 GN=MDH1 PE=1 SV=4"	"4"	"2"	"2"	"2"	"334"	"36.4"	"7.36"	"255.99"	"2.24"	"1"	"1"	"other metabolic processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00056, Pf02866"	"4190"	"ENSG00000014641"	"MDH1"	"B2R5V5; B4DUN2; B7Z3I7; F5H098; hsa:4190; P40925; Q6I9V0"	"Sterol regulatory element-binding proteins (SREBP) signaling; TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Clear cell renal cell carcinoma pathways; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; TCA cycle in senescence; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"Gluconeogenesis"	"9"	"0"	"277.9"	"160.7"	"221.5"	"151.6"	"221.0"	"237.2"	"240.4"	"177.6"	"136.5"	"278.8"	"442.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3B7"	"39S ribosomal protein L11, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL11 PE=1 SV=1"	"4"	"1"	"2"	"1"	"192"	"20.7"	"9.91"	"288.40"	"2.24"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00298, Pf03946"	"65003"	"ENSG00000174547"	"MRPL11"	"A6NLT0; A8K219; hsa:65003; Q32P46; Q96Q73; Q9Y3B7"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WYQ5"	"Microprocessor complex subunit DGCR8 OS=Homo sapiens OX=9606 GN=DGCR8 PE=1 SV=1"	"1"	"1"	"1"	"1"	"773"	"86.0"	"5.95"	""	"2.24"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00035"	"54487"	"ENSG00000128191"	"DGCR8"	"B2R8G1; hsa:54487; Q6DCB2; Q6MZE9; Q6Y2L0; Q8WYQ5; Q96G39; Q96GP8; Q9H6L8; Q9H6T7; Q9NRW2"	"miRNA biogenesis; exRNA mechanism of action and biogenesis; DDX1 as a regulatory component of the Drosha microprocessor; 22q11.2 copy number variation syndrome"	"Transcriptional Regulation by MECP2; MicroRNA (miRNA) biogenesis"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75052"	"Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein OS=Homo sapiens OX=9606 GN=NOS1AP PE=1 SV=3"	"1"	"1"	"1"	"1"	"506"	"56.1"	"6.30"	""	"2.24"	""	"1"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00640"	"9722"	"ENSG00000198929"	"NOS1AP"	"B7ZLF5; hsa:9722; O43564; O75052; Q3T551; Q5VU95"	"Sudden infant death syndrome (SIDS) susceptibility pathways"	""	"1"	"0"	"14.7"	"12.1"	"18.8"	"24.6"	"25.5"	"27.2"	"43.1"	"47.5"	"56.8"	"95.4"	"93.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQ75"	"Protein CMSS1 OS=Homo sapiens OX=9606 GN=CMSS1 PE=1 SV=2"	"3"	"1"	"2"	"1"	"279"	"31.9"	"9.19"	"255.91"	"2.24"	"1"	"1"	""	""	""	"Pf14617"	"84319"	"ENSG00000184220"	"CMSS1"	"A8K5S7; B4DUM1; E9PHS3; hsa:84319; Q9BQ75"	""	""	"0"	"0"	"87.6"	"56.5"	"72.8"	"68.1"	"76.7"	"89.7"	"186.9"	"176.5"	"117.5"	"211.1"	"305.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23368"	"NAD-dependent malic enzyme, mitochondrial OS=Homo sapiens OX=9606 GN=ME2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"584"	"65.4"	"7.61"	"328.65"	"2.23"	"1"	"1"	"other metabolic processes;other biological processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf00390, Pf03949"	"4200"	"ENSG00000082212"	"ME2"	"B2R8J2; hsa:4200; P23368; Q9BWL6; Q9BYG1; Q9H4B2"	"TCA cycle in senescence"	"Citric acid cycle (TCA cycle)"	"2"	"0"	"54.0"	"40.2"	"55.3"	"49.6"	"55.9"	"62.1"	"95.6"	"103.5"	"77.6"	"140.6"	"206.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95298"	"NADH dehydrogenase [ubiquinone] 1 subunit C2 OS=Homo sapiens OX=9606 GN=NDUFC2 PE=1 SV=1"	"6"	"1"	"1"	"1"	"119"	"14.2"	"8.98"	""	"2.23"	""	"1"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;mitochondrion;other cytoplasmic organelle;other cell component"	"transporter activity"	"Pf06374"	"4718"	"ENSG00000151366"	"NDUFC2"	"E9PNU8; E9PRB2; hsa:4718; O95298; Q549M5; Q6FIH8; Q9UBJ9"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Neutrophil degranulation; Complex I biogenesis"	"6"	"0"	"138.8"	"110.7"	"107.1"	"92.5"	"125.6"	"132.7"	"205.0"	"181.0"	"137.0"	"250.7"	"290.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00257"	"E3 SUMO-protein ligase CBX4 OS=Homo sapiens OX=9606 GN=CBX4 PE=1 SV=3"	"1"	"1"	"2"	"1"	"560"	"61.3"	"9.36"	"282.96"	"2.23"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00385, Pf17218"	"8535"	"ENSG00000141582"	"CBX4"	"B1PJR7; hsa:8535; O00257; Q6TPI8; Q96C04"	""	"SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Oxidative Stress Induced Senescence; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Regulation of PTEN gene transcription"	"8"	"0"	"42.1"	"28.9"	"32.8"	"35.4"	"34.0"	"40.4"	"161.0"	"153.2"	"143.7"	"171.7"	"232.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15517"	"Corneodesmosin OS=Homo sapiens OX=9606 GN=CDSN PE=1 SV=3"	"2"	"1"	"2"	"1"	"529"	"51.5"	"8.35"	"307.01"	"2.23"	"1"	"1"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;other cell component"	"other molecular function"	""	"1041"	"ENSG00000137197; ENSG00000237114; ENSG00000237123; ENSG00000237165"	"CDSN"	"B0S7V2; B0UYZ7; hsa:1041; O43509; Q15517; Q5SQ85; Q5STD2; Q7LA70; Q7LA71; Q86Z04; Q8IZU4; Q8IZU5; Q8IZU6; Q8N5P3; Q95IF9; Q9NP52; Q9NPE0; Q9NPG5; Q9NRH4; Q9NRH5; Q9NRH6; Q9NRH7; Q9NRH8; Q9UBH8; Q9UIN6; Q9UIN7; Q9UIN8; Q9UIN9; Q9UIP0"	""	"Formation of the cornified envelope"	"1"	"0"	"39.7"	"11.6"	"71.5"	"14.7"	"12.3"	"17.0"	"22.9"	"30.7"	"22.4"	"46.5"	"40.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96DE0"	"U8 snoRNA-decapping enzyme OS=Homo sapiens OX=9606 GN=NUDT16 PE=1 SV=2"	"8"	"1"	"2"	"1"	"195"	"21.3"	"6.89"	"306.21"	"2.23"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00293"	"131870"	"ENSG00000198585"	"NUDT16"	"B4E3B4; E9PED4; F5GYJ1; hsa:131870; Q96DE0; Q96N82"	""	"Phosphate bond hydrolysis by NUDT proteins"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95239"	"Chromosome-associated kinesin KIF4A OS=Homo sapiens OX=9606 GN=KIF4A PE=1 SV=3"	"1"	"1"	"2"	"1"	"1232"	"139.8"	"6.27"	"271.14"	"2.22"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00225"	"24137"	"ENSG00000090889"	"KIF4A"	"B2R7V5; D3DVU4; hsa:24137; O95239; Q86TN3; Q86XX7; Q9NNY6; Q9NY24; Q9UMW3"	"Retinoblastoma gene in cancer"	"Recycling pathway of L1; COPI-dependent Golgi-to-ER retrograde traffic; MHC class II antigen presentation; Kinesins"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00232"	"26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3"	"2"	"1"	"1"	"1"	"456"	"52.9"	"7.65"	""	"2.22"	""	"1"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf01399, Pf18098"	"5718"	"ENSG00000197170"	"PSMD12"	"A6NP15; hsa:5718; O00232; Q53HA2; Q6P053"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"65"	"0"	"26.2"	"23.4"	"31.6"	"30.5"	"29.6"	"36.9"	"39.5"	"33.3"	"29.9"	"36.9"	"52.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T2T1"	"MAGUK p55 subfamily member 7 OS=Homo sapiens OX=9606 GN=MPP7 PE=1 SV=1"	"2"	"1"	"2"	"1"	"576"	"65.5"	"7.14"	"252.95"	"2.22"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00018, Pf00595, Pf00625, Pf02828"	"143098"	"ENSG00000150054"	"MPP7"	"B2RCC9; B4DWL9; B5MDZ3; D3DRW3; hsa:143098; Q5T2T0; Q5T2T1; Q8IY28"	""	"RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOQ GTPase cycle; RHOG GTPase cycle; RHOJ GTPase cycle"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IWA0"	"WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1"	"1"	"1"	"1"	"1"	"830"	"94.4"	"5.96"	""	"2.22"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00400"	"84128"	"ENSG00000115368"	"WDR75"	"hsa:84128; Q8IWA0; Q96J10; Q9H8U8; Q9H9U5; Q9H9V8; Q9UIX2"	""	"rRNA modification in the nucleus and cytosol; Major pathway of rRNA processing in the nucleolus and cytosol"	"2"	"0"	"16.2"	"11.1"	"23.0"	"20.9"	"18.5"	"20.1"	"35.7"	"38.2"	"29.2"	"51.7"	"65.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16560"	"U11/U12 small nuclear ribonucleoprotein 35 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP35 PE=1 SV=1"	"6"	"1"	"2"	"1"	"246"	"29.4"	"9.86"	"341.94"	"2.22"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"11066"	"ENSG00000184209"	"SNRNP35"	"A8K262; hsa:11066; Q16560; Q5XKN9"	""	"mRNA Splicing - Minor Pathway"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P16383"	"GC-rich sequence DNA-binding factor 2 OS=Homo sapiens OX=9606 GN=GCFC2 PE=1 SV=2"	"3"	"2"	"3"	"2"	"781"	"89.3"	"5.99"	"570.83"	"2.22"	"2"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity"	"Pf07842"	"6936"	"ENSG00000005436"	"GCFC2"	"A4UHQ8; A4UHQ9; hsa:6936; O95032; P16383; Q53TY0; Q6P2F2"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"31.6"	"24.0"	"34.4"	"27.6"	"29.2"	"21.9"	"71.3"	"70.0"	"55.6"	"107.3"	"191.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P1K2"	"Polyamine-modulated factor 1 OS=Homo sapiens OX=9606 GN=PMF1 PE=1 SV=2"	"6"	"1"	"1"	"1"	"205"	"23.3"	"5.49"	""	"2.22"	""	"1"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf03980"	"100527963; 11243"	"ENSG00000160783"	"PMF1"	"A8K0C5; hsa:100527963; hsa:11243; Q5TCJ8; Q5TCJ9; Q5TCK0; Q5TCK1; Q5TCK3; Q69YZ9; Q6P1K2; Q6PHR4; Q6ZVE6; Q86VJ6; Q8N4T6; Q9UBQ3"	""	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5TC63"	"Growth hormone-regulated TBC protein 1 OS=Homo sapiens OX=9606 GN=GRTP1 PE=1 SV=4"	"3"	"1"	"1"	"1"	"336"	"38.5"	"8.78"	""	"2.22"	""	"1"	"other biological processes"	""	"enzyme regulator activity"	"Pf00566"	"79774"	"ENSG00000139835"	"GRTP1"	"B9A6K2; hsa:79774; Q2M232; Q5TC63; Q5TC64; Q66K26; Q6P659; Q8N528; Q9H695"	""	""	"0"	"0"	"13.3"	"11.0"	"19.2"	"19.0"	"18.6"	"17.7"	"38.5"	"34.7"	"49.2"	"75.0"	"108.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9C093"	"Sperm flagellar protein 2 OS=Homo sapiens OX=9606 GN=SPEF2 PE=1 SV=2"	"0"	"1"	"1"	"1"	"1822"	"209.7"	"5.54"	""	"2.22"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"non-structural extracellular;cytoskeleton;ER/Golgi;other cell component"	""	"Pf00406, Pf06294"	"79925"	"ENSG00000152582"	"SPEF2"	"hsa:79925; Q2TAC9; Q96LL6; Q9C093; Q9H5C7; Q9H5Q7"	""	""	"0"	"0"	"67.5"	"30.5"	"65.5"	"55.9"	"65.5"	"61.5"	"65.9"	"77.1"	"54.8"	"79.0"	"116.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6W2J9"	"BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1"	"1"	"1"	"2"	"1"	"1755"	"192.1"	"6.48"	"247.99"	"2.21"	"1"	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf12796, Pf15808, Pf16553"	"54880"	"ENSG00000183337"	"BCOR"	"D3DWB3; D3DWB4; hsa:54880; Q29RF6; Q6P4B6; Q6W2J9; Q7Z2K7; Q8TEB4; Q96DB3; Q9H232; Q9H233; Q9HCJ7; Q9NXF2"	"Ectoderm differentiation; Pathways affected in adenoid cystic carcinoma; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma"	""	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13489"	"Ribonuclease inhibitor OS=Homo sapiens OX=9606 GN=RNH1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"461"	"49.9"	"4.82"	"388.81"	"2.21"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf13516, Pf18779"	"6050"	"ENSG00000023191; ENSG00000276230"	"RNH1"	"hsa:6050; P13489; Q8IZK8; Q96FD7; Q9BQ80; Q9UDK6"	""	""	"0"	"0"	"23.9"	"18.2"	"23.3"	"22.9"	"28.2"	"23.9"	"34.4"	"34.9"	"25.5"	"37.1"	"51.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N3R9"	"MAGUK p55 subfamily member 5 OS=Homo sapiens OX=9606 GN=MPP5 PE=1 SV=3"	"4"	"2"	"3"	"2"	"675"	"77.2"	"6.14"	"644.56"	"2.21"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf00595, Pf00625, Pf02828, Pf07653, Pf09060"	"64398"	"ENSG00000072415"	"PALS1"	"A1L380; hsa:64398; Q7Z631; Q86T98; Q8N3R9; Q8N7I5; Q9H9Q0"	"Epithelial to mesenchymal transition in colorectal cancer; Complement system in neuronal development and plasticity"	"Tight junction interactions; SARS-CoV-2 targets PDZ proteins in cell-cell junction; SARS-CoV-1 targets PDZ proteins in cell-cell junction"	"5"	"0"	"68.0"	"58.2"	"48.6"	"51.3"	"60.9"	"60.7"	"129.3"	"108.9"	"71.0"	"116.8"	"121.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UHN6"	"Cell surface hyaluronidase OS=Homo sapiens OX=9606 GN=CEMIP2 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1383"	"154.3"	"8.15"	"233.50"	"2.21"	"1"	"1"	"other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf10162, Pf15711"	"23670"	"ENSG00000135048"	"CEMIP2"	"A6H8W9; B2RTQ6; hsa:23670; Q5T838; Q5T839; Q5T840; Q5T841; Q8NBP6; Q9P2D5; Q9UHN6"	""	""	"0"	"0"	"23.8"	"12.2"	"22.6"	"13.0"	"10.6"	"10.3"	"19.5"	"17.1"	"16.2"	"21.9"	"36.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3D9"	"28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2"	"5"	"1"	"2"	"1"	"190"	"21.8"	"8.90"	"277.96"	"2.21"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf10484"	"51649"	"ENSG00000181610"	"MRPS23"	"B2R6V3; hsa:51649; Q96Q24; Q9BWH8; Q9P053; Q9Y3D9"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"92.5"	"55.0"	"81.9"	"72.5"	"88.0"	"89.7"	"214.8"	"174.5"	"122.2"	"201.9"	"262.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P032"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 OS=Homo sapiens OX=9606 GN=NDUFAF4 PE=1 SV=1"	"3"	"1"	"2"	"1"	"175"	"20.3"	"8.82"	"250.02"	"2.20"	"1"	"1"	"cell organization and biogenesis;stress response;other biological processes"	"other membranes;cytosol;mitochondrion"	"other molecular function"	"Pf06784"	"29078"	"ENSG00000123545"	"NDUFAF4"	"B2R4J5; hsa:29078; Q9P032"	""	"Complex I biogenesis"	"1"	"0"	"64.9"	"39.9"	"41.3"	"28.7"	"43.7"	"54.6"	"79.2"	"72.8"	"56.8"	"100.7"	"92.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07954"	"Fumarate hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=FH PE=1 SV=3"	"2"	"1"	"2"	"1"	"510"	"54.6"	"8.76"	"233.92"	"2.20"	"1"	"1"	"DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00206, Pf10415"	"2271"	"ENSG00000091483"	"FH"	"B1ANK7; hsa:2271; P07954"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Krebs cycle disorders; Type 2 papillary renal cell carcinoma; Metabolic reprogramming in colon cancer; TCA cycle in senescence; TCA cycle (aka Krebs or citric acid cycle)"	"Citric acid cycle (TCA cycle)"	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52747"	"Zinc finger protein 143 OS=Homo sapiens OX=9606 GN=ZNF143 PE=1 SV=2"	"2"	"1"	"1"	"1"	"638"	"68.9"	"6.05"	""	"2.20"	""	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00096"	"7702"	"ENSG00000166478"	"ZNF143"	"A8K518; B4DLY5; E7ER34; hsa:7702; O75559; P52747; Q8WUK9"	"IL-18 signaling pathway"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 3 Promoter; RNA polymerase II transcribes snRNA genes"	"4"	"0"	"48.2"	"33.7"	"41.0"	"56.7"	"48.0"	"51.7"	"84.4"	"72.3"	"47.1"	"76.9"	"128.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N4Q1"	"Mitochondrial intermembrane space import and assembly protein 40 OS=Homo sapiens OX=9606 GN=CHCHD4 PE=1 SV=1"	"4"	"1"	"1"	"1"	"142"	"16.0"	"4.31"	""	"2.20"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport"	"mitochondrion"	"other molecular function"	"Pf06747"	"131474"	"ENSG00000163528"	"CHCHD4"	"A8K3Z9; hsa:131474; Q8N4Q1; Q96AI2; Q96MY6"	""	"Mitochondrial protein import"	"1"	"0"	"243.5"	"98.2"	"134.1"	"151.2"	"126.2"	"117.6"	"229.0"	"205.6"	"162.8"	"202.8"	"293.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NHQ8"	"Ras association domain-containing protein 8 OS=Homo sapiens OX=9606 GN=RASSF8 PE=1 SV=2"	"3"	"1"	"2"	"1"	"419"	"48.3"	"6.49"	"249.01"	"2.20"	"1"	"1"	"signal transduction"	""	""	"Pf00788"	"11228"	"ENSG00000123094"	"RASSF8"	"A8K1Z0; hsa:11228; O95647; Q5SCI2; Q76KB6; Q8NHQ8"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z2W9"	"39S ribosomal protein L21, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL21 PE=1 SV=2"	"5"	"1"	"1"	"1"	"205"	"22.8"	"9.89"	""	"2.20"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00829"	"219927"	"ENSG00000197345"	"MRPL21"	"A6NKU0; C9JPR2; hsa:219927; Q7Z2W9"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75935"	"Dynactin subunit 3 OS=Homo sapiens OX=9606 GN=DCTN3 PE=1 SV=1"	"6"	"1"	"2"	"1"	"186"	"21.1"	"5.47"	"236.95"	"2.20"	"1"	"1"	"cell cycle OR cell proliferation;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07426"	"11258"	"ENSG00000137100"	"DCTN3"	"A6NII7; B2RBM5; hsa:11258; O75935; Q5T1I5; Q5T1I7; Q5T8G3; Q9BPU8"	""	"MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recruitment of NuMA to mitotic centrosomes; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"11"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P37837"	"Transaldolase OS=Homo sapiens OX=9606 GN=TALDO1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"337"	"37.5"	"6.81"	"305.85"	"2.20"	"1"	"1"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00923"	"6888"	"ENSG00000177156"	"TALDO1"	"B2R8M2; hsa:6888; O00751; P37837; Q8WV32; Q8WZ45"	"Pentose phosphate metabolism; Cori cycle; Metabolic reprogramming in colon cancer"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; NFE2L2 regulates pentose phosphate pathway genes; Pentose phosphate pathway; Insulin effects increased synthesis of Xylulose-5-Phosphate; TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P; TALDO1 deficiency: failed conversion of  Fru(6)P, E4P to SH7P, GA3P"	"9"	"0"	"112.5"	"80.3"	"122.5"	"52.2"	"90.6"	"94.9"	"125.0"	"98.9"	"85.1"	"126.8"	"170.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86XR2"	"Protein Niban 3 OS=Homo sapiens OX=9606 GN=NIBAN3 PE=1 SV=2"	"2"	"1"	"1"	"1"	"697"	"77.4"	"8.63"	""	"2.19"	""	"1"	""	""	""	""	"199786"	"ENSG00000167483"	"NIBAN3"	"B4DNU3; B4DVN7; hsa:199786; Q7Z6H6; Q86XR2; Q86XR3; Q86XR4; Q8TEQ3"	""	""	"0"	"0"	"26.9"	"26.7"	"33.5"	"26.7"	"31.7"	"29.8"	"71.0"	"67.5"	"36.5"	"77.6"	"70.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q32MZ4"	"Leucine-rich repeat flightless-interacting protein 1 OS=Homo sapiens OX=9606 GN=LRRFIP1 PE=1 SV=2"	"1"	"1"	"1"	"1"	"808"	"89.2"	"4.65"	""	"2.19"	""	"1"	"other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09738"	"9208"	"ENSG00000124831"	"LRRFIP1"	"E9PGZ2; hsa:9208; O75766; O75799; Q32MZ4; Q32MZ5; Q53T49; Q6PKG2; Q9Y607"	"IL-18 signaling pathway; 2q37 copy number variation syndrome"	"Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease; LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z4V5"	"Hepatoma-derived growth factor-related protein 2 OS=Homo sapiens OX=9606 GN=HDGFL2 PE=1 SV=1"	"2"	"1"	"1"	"1"	"671"	"74.3"	"7.49"	""	"2.19"	""	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00855, Pf11467"	"84717"	"ENSG00000167674"	"HDGFL2"	"hsa:84717; I3L080; K7EQZ6; Q7Z4V5; Q96GI5; Q9BW08"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P33316"	"Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=DUT PE=1 SV=4"	"5"	"1"	"2"	"1"	"252"	"26.5"	"9.36"	"254.82"	"2.19"	"1"	"1"	"DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;mitochondrion;nucleus"	"signal transduction activity or receptor binding;other molecular function"	"Pf00692"	"1854"	"ENSG00000128951"	"DUT"	"A8K650; B4DPR5; hsa:1854; O14785; P33316; Q16708; Q16860; Q6FHN1; Q6NSA3; Q96Q81"	"Pyrimidine metabolism"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WUM4"	"Programmed cell death 6-interacting protein OS=Homo sapiens OX=9606 GN=PDCD6IP PE=1 SV=1"	"1"	"1"	"2"	"1"	"868"	"96.0"	"6.52"	"313.02"	"2.19"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"non-structural extracellular;plasma membrane;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf03097, Pf13949"	"10015"	"ENSG00000170248"	"PDCD6IP"	"C5MQH7; E9PFU1; hsa:10015; Q6NUS1; Q8WUM4; Q9BX86; Q9NUN0; Q9P2H2; Q9UKL5"	"Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells"	"Budding and maturation of HIV virion; Regulation of necroptotic cell death; Uptake and function of anthrax toxins"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20585"	"DNA mismatch repair protein Msh3 OS=Homo sapiens OX=9606 GN=MSH3 PE=1 SV=4"	"4"	"3"	"4"	"3"	"1137"	"127.3"	"8.02"	"1061.78"	"2.19"	"3"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00488, Pf01624, Pf05188, Pf05192"	"4437"	"ENSG00000113318"	"MSH3"	"A1L480; A1L482; A6NMM6; hsa:4437; P20585; Q6PJT5; Q86UQ6; Q92867"	"Chromosomal and microsatellite instability in colorectal cancer ; DNA repair pathways, full network"	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta); Defective Mismatch Repair Associated With MSH3; Defective Mismatch Repair Associated With MSH2"	"5"	"0"	"12.9"	"9.5"	"13.1"	"12.0"	"11.2"	"16.0"	"30.9"	"23.8"	"16.3"	"20.8"	"27.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14565"	"Meiotic recombination protein DMC1/LIM15 homolog OS=Homo sapiens OX=9606 GN=DMC1 PE=1 SV=2"	"4"	"1"	"1"	"1"	"340"	"37.7"	"5.88"	""	"2.18"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf08423"	"11144"	"ENSG00000100206"	"DMC1"	"A8K9A2; B4DMW6; hsa:11144; Q08AI1; Q14565; Q99498; Q9UH11"	"Ovarian infertility; Primary ovarian insufficiency"	"Meiotic recombination"	"3"	"0"	"3.5"	"5.6"	"8.9"	"14.8"	"9.3"	"7.5"	"28.6"	"32.9"	"25.9"	"40.9"	"57.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6DD87"	"Zinc finger protein 787 OS=Homo sapiens OX=9606 GN=ZNF787 PE=1 SV=4"	"5"	"1"	"1"	"1"	"382"	"40.4"	"7.96"	""	"2.18"	""	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00096, Pf13912"	"126208"	"ENSG00000142409"	"ZNF787"	"A0A087WUD1; hsa:126208; O00455; Q6DD87"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75832"	"26S proteasome non-ATPase regulatory subunit 10 OS=Homo sapiens OX=9606 GN=PSMD10 PE=1 SV=1"	"4"	"1"	"2"	"1"	"226"	"24.4"	"6.10"	"320.75"	"2.18"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf12796"	"5716"	"ENSG00000101843"	"PSMD10"	"hsa:5716; O75832; Q5U0B2; Q8IZK9"	"Proteasome degradation; Parkin-ubiquitin proteasomal system pathway"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"61"	"0"	"41.3"	"25.3"	"39.3"	"20.7"	"40.8"	"27.4"	"37.9"	"38.0"	"32.6"	"59.3"	"92.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRA2"	"Thioredoxin domain-containing protein 17 OS=Homo sapiens OX=9606 GN=TXNDC17 PE=1 SV=1"	"7"	"1"	"2"	"1"	"123"	"13.9"	"5.52"	"368.83"	"2.18"	"1"	"1"	"signal transduction;other biological processes"	"cytosol"	"other molecular function"	"Pf06110"	"84817"	"ENSG00000129235"	"TXNDC17"	"A8K7E8; hsa:84817; Q9BRA2"	""	""	"0"	"0"	"65.4"	"52.6"	"56.5"	"39.7"	"54.6"	"70.4"	"67.6"	"45.6"	"34.3"	"71.4"	"111.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9C0C2"	"182 kDa tankyrase-1-binding protein OS=Homo sapiens OX=9606 GN=TNKS1BP1 PE=1 SV=4"	"1"	"1"	"1"	"1"	"1729"	"181.7"	"4.86"	""	"2.17"	""	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf15327"	"85456"	"ENSG00000149115"	"TNKS1BP1"	"A7E2F8; hsa:85456; Q6PJ35; Q6ZV74; Q9C0C2"	"Ciliary landscape"	"Deadenylation of mRNA; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96SU4"	"Oxysterol-binding protein-related protein 9 OS=Homo sapiens OX=9606 GN=OSBPL9 PE=1 SV=2"	"1"	"1"	"2"	"1"	"736"	"83.1"	"6.18"	"350.47"	"2.17"	"1"	"1"	"other metabolic processes;transport"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00169, Pf01237"	"114883"	"ENSG00000117859"	"OSBPL9"	"B1AKJ8; B3KPQ4; D3DQ31; hsa:114883; Q5TFC0; Q6IA67; Q86YQ3; Q8NB17; Q8TAS8; Q96SK4; Q96SU4; Q9H9X2"	""	"Synthesis of bile acids and bile salts"	"1"	"0"	"30.3"	"18.2"	"20.6"	"35.4"	"19.3"	"27.3"	"28.4"	"35.6"	"26.3"	"33.7"	"47.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TBB5"	"Kelch domain-containing protein 4 OS=Homo sapiens OX=9606 GN=KLHDC4 PE=1 SV=1"	"2"	"1"	"1"	"1"	"520"	"57.9"	"5.72"	""	"2.17"	""	"1"	""	""	""	"Pf07646, Pf13418, Pf13854, Pf13964"	"54758"	"ENSG00000104731"	"KLHDC4"	"D3DUN3; D3DUN4; D3DUN5; hsa:54758; Q8TBB5; Q96F29; Q9BVN3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60423"	"Phospholipid-transporting ATPase IK OS=Homo sapiens OX=9606 GN=ATP8B3 PE=2 SV=4"	"1"	"2"	"2"	"1"	"1300"	"146.7"	"7.90"	"255.71"	"2.17"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"transporter activity;other molecular function"	"Pf00122, Pf00702, Pf13246, Pf16209, Pf16212"	"148229"	"ENSG00000130270"	"ATP8B3"	"hsa:148229; O60423; Q7Z485; Q8IVB8; Q8N4Y8; Q96M22"	"Complement system in neuronal development and plasticity"	"Ion transport by P-type ATPases"	"2"	"0"	"22.2"	"16.6"	"27.4"	"20.4"	"24.0"	"29.1"	"39.9"	"51.8"	"29.3"	"49.4"	"63.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5SZI1"	"Low-density lipoprotein receptor class A domain-containing protein 2 OS=Homo sapiens OX=9606 GN=LDLRAD2 PE=2 SV=1"	"5"	"1"	"1"	"1"	"272"	"28.6"	"5.64"	""	"2.17"	""	"1"	""	"other membranes"	""	"Pf00057"	"401944"	"ENSG00000187942"	"LDLRAD2"	"B9EJB3; hsa:401944; Q5SZI1; Q6ZSN5"	""	""	"0"	"0"	"62.3"	"43.7"	"58.9"	"69.7"	"54.7"	"74.1"	"99.8"	"105.5"	"92.6"	"89.0"	"120.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55010"	"Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2"	"2"	"1"	"2"	"1"	"431"	"49.2"	"5.58"	"285.29"	"2.17"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf01873, Pf02020"	"1983"	"ENSG00000100664"	"EIF5"	"hsa:1983; P55010; Q53XB3; Q9H5N2; Q9UG48"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"4"	"0"	"29.9"	"21.0"	"38.3"	"35.8"	"37.0"	"37.3"	"115.0"	"118.4"	"94.7"	"146.3"	"211.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IVH8"	"Mitogen-activated protein kinase kinase kinase kinase 3 OS=Homo sapiens OX=9606 GN=MAP4K3 PE=1 SV=1"	"1"	"1"	"1"	"1"	"894"	"101.3"	"7.56"	""	"2.17"	""	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00780"	"8491"	"ENSG00000011566"	"MAP4K3"	"hsa:8491; Q6IQ39; Q8IVH7; Q8IVH8; Q9UDM5; Q9Y6R5"	"MAPK signaling pathway; Angiopoietin-like protein 8 regulatory pathway; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-YAP signaling; Insulin signaling; Pleural mesothelioma"	""	"6"	"0"	"26.7"	"19.6"	"20.4"	"20.0"	"26.0"	"27.2"	"71.4"	"138.4"	"125.2"	"146.2"	"195.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P59780"	"AP-3 complex subunit sigma-2 OS=Homo sapiens OX=9606 GN=AP3S2 PE=2 SV=1"	"3"	"1"	"1"	"1"	"193"	"22.0"	"5.22"	""	"2.17"	""	"1"	"cell organization and biogenesis;transport"	"other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf01217"	"10239"	"ENSG00000157823"	"AP3S2"	"B2R677; B4DGQ3; hsa:10239; O09077; O09149; P59780; Q53H83; Q99589"	""	""	"0"	"0"	"26.6"	"13.3"	"14.9"	"16.4"	"18.4"	"23.8"	"67.4"	"60.1"	"48.0"	"74.6"	"79.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H7L9"	"Sin3 histone deacetylase corepressor complex component SDS3 OS=Homo sapiens OX=9606 GN=SUDS3 PE=1 SV=2"	"3"	"1"	"1"	"1"	"328"	"38.1"	"5.66"	""	"2.17"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf08598"	"64426"	"ENSG00000111707"	"SUDS3"	"hsa:64426; Q4KMQ5; Q8N6H0; Q9H7L9; Q9H8D2"	""	"Ub-specific processing proteases; NoRC negatively regulates rRNA expression; HDACs deacetylate histones; Potential therapeutics for SARS"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O76013"	"Keratin, type I cuticular Ha6 OS=Homo sapiens OX=9606 GN=KRT36 PE=1 SV=1"	"3"	"2"	"3"	"1"	"467"	"52.2"	"4.94"	"520.10"	"2.16"	"2"	"1"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	"bone, tooth or skin structural activity"	"Pf00038"	"8689"	"ENSG00000126337"	"KRT36"	"hsa:8689; O76013; Q86XG4"	""	"Formation of the cornified envelope"	"2"	"0"	"70.2"	"54.5"	"63.8"	"57.2"	"492.9"	"80.0"	"112.1"	"125.6"	"113.1"	"167.9"	"225.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4A5"	"Transformation/transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3"	"0"	"2"	"3"	"1"	"3859"	"437.3"	"8.19"	"489.02"	"2.16"	"2"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00454, Pf02259, Pf20175, Pf20206"	"8295"	"ENSG00000196367"	"TRRAP"	"A4D265; hsa:8295; O75218; Q9Y4A5; Q9Y631; Q9Y6H4"	"Rett syndrome causing genes"	"Ub-specific processing proteases; HATs acetylate histones; Formation of the beta-catenin:TCF transactivating complex"	"4"	"1"	"134.0"	"57.7"	"74.1"	"55.8"	"58.6"	"63.4"	"90.4"	"76.3"	"66.6"	"84.0"	"162.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z460"	"CLIP-associating protein 1 OS=Homo sapiens OX=9606 GN=CLASP1 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1538"	"169.3"	"9.03"	"261.48"	"2.16"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02985, Pf12348"	"23332"	"ENSG00000074054"	"CLASP1"	"A2RU21; B7ZLX3; F5GWS0; hsa:23332; O75118; Q2KHQ9; Q5H9P0; Q7Z460; Q8N5B8; Q9BQT5"	"Microtubule cytoskeleton regulation; Splicing factor NOVA regulated synaptic proteins; 7q11.23 copy number variation syndrome"	"Separation of Sister Chromatids; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Role of ABL in ROBO-SLIT signaling"	"17"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q03164"	"Histone-lysine N-methyltransferase 2A OS=Homo sapiens OX=9606 GN=KMT2A PE=1 SV=5"	"0"	"1"	"1"	"1"	"3969"	"431.5"	"9.09"	""	"2.16"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00628, Pf00856, Pf02008, Pf05964, Pf05965, Pf13771"	"4297"	"ENSG00000118058"	"KMT2A"	"E9PQG7; hsa:4297; Q03164; Q13743; Q13744; Q14845; Q16364; Q59FF2; Q6UBD1; Q9HBJ3; Q9UD94; Q9UMA3"	"Histone modifications"	"RUNX1 regulates transcription of genes involved in differentiation of HSCs; Formation of WDR5-containing histone-modifying complexes; PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Transcriptional regulation of granulopoiesis"	"6"	"0"	"13.8"	"8.6"	"16.8"	"11.9"	"12.0"	"16.3"	"15.1"	"23.2"	"15.4"	"22.9"	"30.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99549"	"M-phase phosphoprotein 8 OS=Homo sapiens OX=9606 GN=MPHOSPH8 PE=1 SV=2"	"1"	"1"	"2"	"1"	"860"	"97.1"	"6.06"	"266.26"	"2.16"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00385, Pf12796"	"54737"	"ENSG00000196199"	"MPHOSPH8"	"B7Z6F9; hsa:54737; Q5JPE5; Q5JTQ0; Q86TK3; Q96MK4; Q99549; Q9BTP1"	""	""	"0"	"0"	"21.4"	"15.6"	"22.9"	"22.3"	"29.2"	"21.7"	"69.8"	"57.1"	"33.3"	"69.9"	"92.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51178"	"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 OS=Homo sapiens OX=9606 GN=PLCD1 PE=1 SV=2"	"2"	"1"	"1"	"1"	"756"	"85.6"	"6.70"	""	"2.16"	""	"1"	"other metabolic processes;transport;signal transduction"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00168, Pf00387, Pf00388, Pf09279"	"5333"	"ENSG00000187091"	"PLCD1"	"B3KR14; hsa:5333; P51178; Q86VN8"	"Myometrial relaxation and contraction pathways; GPR40 pathway; Non-genomic actions of 1,25 dihydroxyvitamin D3; Resistin as a regulator of inflammation; Orexin receptor pathway"	"Synthesis of IP3 and IP4 in the cytosol"	"6"	"0"	"18.8"	"7.2"	"134.4"	"18.3"	"14.2"	"21.5"	"37.2"	"26.2"	"22.7"	"41.4"	"40.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14493"	"Histone RNA hairpin-binding protein OS=Homo sapiens OX=9606 GN=SLBP PE=1 SV=1"	"3"	"1"	"2"	"1"	"270"	"31.3"	"7.47"	"297.73"	"2.16"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf15247"	"7884"	"ENSG00000163950"	"SLBP"	"B3KRJ5; hsa:7884; Q14493"	"8p23.1 copy number variation syndrome; 4p16.3 copy number variation"	"RNA Polymerase II Transcription Termination; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs; Transport of the SLBP Dependant Mature mRNA"	"5"	"0"	"49.7"	"36.1"	"42.5"	"41.7"	"31.3"	"50.9"	"90.2"	"84.2"	"70.6"	"87.2"	"117.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q08209"	"Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform OS=Homo sapiens OX=9606 GN=PPP3CA PE=1 SV=1"	"2"	"1"	"2"	"1"	"521"	"58.7"	"5.86"	"315.66"	"2.15"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00149"	"5530"	"ENSG00000138814"	"PPP3CA"	"A1A441; A8K3B7; A8W6Z7; A8W6Z8; B5BUA2; hsa:5530; Q08209; Q8TAW9"	"Physiological and pathological hypertrophy of the heart; Energy metabolism; MicroRNAs in cardiomyocyte hypertrophy; Alzheimer's disease and miRNA effects; Spinal cord injury; Amyotrophic lateral sclerosis (ALS); T cell receptor and co-stimulatory signaling; Cardiac hypertrophic response; Initiation of transcription and translation elongation at the HIV-1 LTR; G protein signaling pathways; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Mitochondrial gene expression; Serotonin and anxiety-related events; Serotonin and anxiety; Wnt signaling; Vitamin D in inflammatory diseases; Fragile X syndrome; Alzheimer's disease; Th17 cell differentiation pathway"	"DARPP-32 events; FCERI mediated Ca+2 mobilization; Ca2+ pathway; CLEC7A (Dectin-1) induces NFAT activation; Calcineurin activates NFAT"	"25"	"0"	"91.0"	"63.7"	"84.7"	"72.8"	"76.3"	"96.5"	"123.9"	"109.2"	"92.3"	"148.7"	"248.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRG0"	"Chromatin accessibility complex protein 1 OS=Homo sapiens OX=9606 GN=CHRAC1 PE=1 SV=1"	"6"	"1"	"1"	"1"	"131"	"14.7"	"5.10"	""	"2.15"	""	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00808"	"54108"	"ENSG00000104472"	"CHRAC1"	"hsa:54108; Q9NRG0"	"Acute viral myocarditis"	""	"1"	"0"	"14.5"	"13.8"	"18.2"	"10.6"	"19.7"	"16.4"	"22.4"	"26.0"	"21.5"	"31.9"	"40.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19838"	"Nuclear factor NF-kappa-B p105 subunit OS=Homo sapiens OX=9606 GN=NFKB1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"968"	"105.3"	"5.40"	"289.02"	"2.15"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;cytosol;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00023, Pf00531, Pf00554, Pf16179"	"4790"	"ENSG00000109320"	"NFKB1"	"A8K5Y5; B3KVE8; hsa:4790; P19838; Q68D84; Q86V43; Q8N4X7; Q9NZC0"	"Osteopontin signaling; Selenium micronutrient network; Vitamin B12 metabolism; MicroRNAs in cardiomyocyte hypertrophy; Transcription factors regulate miRNAs related to cardiac hypertrophy; Folate metabolism; IL-1 signaling pathway; RANKL/RANK signaling pathway; Leptin signaling pathway; TNF-related weak inducer of apoptosis (TWEAK) signaling pathway; Prolactin signaling pathway; Alzheimer's disease and miRNA effects; Neural crest differentiation; IL-17 signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; B cell receptor signaling pathway; TNF-alpha signaling pathway; AGE/RAGE pathway; Corticotropin-releasing hormone signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Quercetin and Nf-kB / AP-1 induced apoptosis; PDGF pathway; Apoptosis; T cell receptor and co-stimulatory signaling; Aryl hydrocarbon receptor pathway; Ebstein-Barr virus LMP1 signaling; Cardiac hypertrophic response; Apoptosis-related network due to altered Notch3 in ovarian cancer; IL1 and megakaryocytes in obesity; Myometrial relaxation and contraction pathways; Melatonin metabolism and effects; RAC1/PAK1/p38/MMP2 pathway; Initiation of transcription and translation elongation at the HIV-1 LTR; Photodynamic therapy-induced NF-kB survival signaling; NAD metabolism, sirtuins and aging; Hepatitis C and hepatocellular carcinoma; MAPK signaling pathway; Apoptosis modulation by HSP70; MAPK and NFkB signaling pathways inhibited by Yersinia YopJ; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; TLR4 signaling and tolerance; Toll-like receptor signaling related to MyD88; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; Novel intracellular components of RIG-I-like receptor pathway; MYD88 distinct input-output pathway; ATM signaling in development and disease ; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Oxidative damage response; IL-4 signaling pathway; Prion disease pathway; NO/cGMP/PKG mediated neuroprotection; Oxidative stress response; Fibrin complement receptor 3 signaling pathway; PI3K-Akt signaling pathway; Ebola virus infection in host; Ras signaling; Pancreatic adenocarcinoma pathway; miRNA role in immune response in sepsis; ncRNAs involved in STAT3 signaling in hepatocellular carcinoma; Non-genomic actions of 1,25 dihydroxyvitamin D3; Ciliary landscape; Nonalcoholic fatty liver disease; Supression of HMGB1 mediated inflammation by THBD; Altered glycosylation of MUC1 in tumor microenvironment; Resistin as a regulator of inflammation; Vitamin D in inflammatory diseases; Signal transduction through IL1R; Interactions between immune cells and microRNAs in tumor microenvironment; Canonical NF-kB pathway; Cancer immunotherapy by PD-1 blockade; Measles virus infection; Cytosolic DNA-sensing pathway; Small cell lung cancer; Gastrin signaling pathway; Hepatitis B infection; Head and neck squamous cell carcinoma; Aspirin and miRNAs; IL-18 signaling pathway; Autosomal recessive osteopetrosis pathways; FGF23 signaling in hypophosphatemic rickets and related disorders; TGF-beta receptor signaling in skeletal dysplasias; Kisspeptin/kisspeptin receptor system in the ovary; Activation of NLRP3 inflammasome by SARS-CoV-2; Host-pathogen interaction of human coronaviruses - interferon induction; 16p11.2 proximal deletion syndrome; STING pathway in Kawasaki-like disease and COVID-19; RAS and bradykinin pathways in COVID-19; Mitochondrial immune response to SARS-CoV-2; SARS-CoV-2 innate immunity evasion and cell-specific immune response; Modulators of TCR signaling and T cell activation; Neuroinflammation and glutamatergic signaling; Pleural mesothelioma; Prostaglandin signaling; Antiviral and anti-inflammatory effects of Nrf2 on SARS-CoV-2 pathway; Inclusion body myositis; Alzheimer's disease; Th17 cell differentiation pathway; Ulcerative colitis signaling; SARS-CoV-2 mitochondrial chronic oxidative stress and endothelial dysfunction; Modulation of PI3K-Akt-mTOR signaling by bioactive sphingolipids; Inflammatory bowel disease signaling; Genetic causes of porto-sinusoidal vascular disease; TROP2 regulatory signaling; Autophagy in pancreatic ductal adenocarcinoma; A network map of Macrophage-stimulating protein (MSP) signaling; Disturbed pathways in Duchenne Muscular Dystrophy; TAR syndrome; Role of hypoxia, angiogenesis, and FGF pathway in OA chondrocyte hypertrophy; 10q22q23 copy number variation; TGF-beta receptor signaling; Notch signaling pathway; T-cell receptor signaling pathway; Sudden infant death syndrome (SIDS) susceptibility pathways; Estrogen signaling pathway; Toll-like receptor signaling pathway"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Activation of NF-kappaB in B cells; Neutrophil degranulation; Transcriptional regulation of white adipocyte differentiation; HCMV Early Events; Senescence-Associated Secretory Phenotype (SASP); Transcriptional Regulation by VENTX; PKMTs methylate histone lysines; RIP-mediated NFkB activation via ZBP1; NF-kB is activated and signals survival; TAK1-dependent IKK and NF-kappa-B activation  ; IkBA variant leads to EDA-ID; MAP3K8 (TPL2)-dependent MAPK1/3 activation; TRAF6 mediated NF-kB activation; The NLRP3 inflammasome; Purinergic signaling in leishmaniasis infection; SARS-CoV-1 activates/modulates innate immune responses; CD209 (DC-SIGN) signaling; Interleukin-1 processing; CLEC7A/inflammasome pathway; Regulated proteolysis of p75NTR; DEx/H-box helicases activate type I IFN and inflammatory cytokines production"	"142"	"0"	"29.4"	"16.2"	"27.2"	"31.2"	"22.1"	"35.2"	"57.6"	"47.0"	"33.2"	"52.9"	"76.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z417"	"Nuclear fragile X mental retardation-interacting protein 2 OS=Homo sapiens OX=9606 GN=NUFIP2 PE=1 SV=1"	"2"	"2"	"2"	"2"	"695"	"76.1"	"8.70"	"247.70"	"2.14"	"1"	"1"	""	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity"	"Pf15293"	"57532"	"ENSG00000108256"	"NUFIP2"	"A1L3A6; A1L3A7; hsa:57532; Q7Z417; Q9P2M5"	""	""	"0"	"0"	"129.5"	"81.2"	"112.9"	"99.6"	"117.1"	"142.3"	"389.9"	"421.4"	"352.0"	"590.4"	"822.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRP1"	"Programmed cell death protein 2-like OS=Homo sapiens OX=9606 GN=PDCD2L PE=1 SV=1"	"3"	"1"	"2"	"1"	"358"	"39.4"	"4.86"	"288.95"	"2.14"	"1"	"1"	"cell cycle OR cell proliferation;other biological processes"	"other cell component"	""	"Pf04194"	"84306"	"ENSG00000126249"	"PDCD2L"	"hsa:84306; Q9BRP1"	""	""	"0"	"0"	"60.2"	"32.4"	"60.9"	"59.2"	"56.2"	"56.9"	"122.5"	"125.5"	"89.9"	"116.6"	"129.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UGM6"	"Tryptophan--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=WARS2 PE=1 SV=1"	"2"	"1"	"1"	"1"	"360"	"40.1"	"9.28"	""	"2.14"	""	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf00579"	"10352"	"ENSG00000116874"	"WARS2"	"B1ALR1; B2R9D4; hsa:10352; Q53FT4; Q5VUD2; Q86TQ0; Q9UGM6"	""	"Mitochondrial tRNA aminoacylation"	"1"	"0"	"96.2"	"52.6"	"81.7"	"77.9"	"77.0"	"93.2"	"269.9"	"230.3"	"156.8"	"281.6"	"463.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NY27"	"Serine/threonine-protein phosphatase 4 regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PPP4R2 PE=1 SV=3"	"1"	"1"	"2"	"1"	"417"	"46.9"	"4.54"	"254.28"	"2.14"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf09184"	"151987"	"ENSG00000163605"	"PPP4R2"	"A8K1I6; hsa:151987; Q2TAJ9; Q498B8; Q8WXX6; Q9NY27"	"16p11.2 proximal deletion syndrome"	"Processing of DNA double-strand break ends"	"2"	"0"	"175.5"	"96.9"	"163.7"	"129.4"	"169.5"	"158.7"	"241.4"	"219.4"	"174.1"	"241.9"	"353.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P43307"	"Translocon-associated protein subunit alpha OS=Homo sapiens OX=9606 GN=SSR1 PE=1 SV=3"	"3"	"1"	"2"	"1"	"286"	"32.2"	"4.49"	"284.15"	"2.14"	"1"	"1"	"transport;other biological processes"	"other membranes;ER/Golgi"	""	"Pf03896"	"6745"	"ENSG00000124783"	"SSR1"	"A8K685; hsa:6745; P43307; Q53GX2; Q53H19; Q5TAM3; Q6IB43; Q8NBH9; Q96IA2; Q9TNQ8; Q9UN49"	""	"SRP-dependent cotranslational protein targeting to membrane; XBP1(S) activates chaperone genes"	"2"	"0"	"49.9"	"29.4"	"33.5"	"40.4"	"40.3"	"45.3"	"62.3"	"61.3"	"38.0"	"77.5"	"98.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14739"	"Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2"	"1"	"1"	"2"	"1"	"615"	"70.7"	"9.36"	"270.91"	"2.14"	"1"	"1"	"other metabolic processes;other biological processes"	"other membranes;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01222, Pf09465"	"3930"	"ENSG00000143815"	"LBR"	"B2R5P3; hsa:3930; Q14739; Q14740; Q53GU7; Q59FE6"	"Gastric cancer network 2; ATM signaling in development and disease ; Envelope proteins and their potential roles in EDMD physiopathology; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Cholesterol biosynthesis with skeletal dysplasias; Cholesterol synthesis disorders; Cholesterol metabolism; Enterocyte cholesterol metabolism"	"RHOC GTPase cycle; RHOA GTPase cycle; RHOD GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; Regulation of MECP2 expression and activity; Initiation of Nuclear Envelope (NE) Reformation; Cholesterol biosynthesis"	"19"	"0"	"62.9"	"52.4"	"62.5"	"50.1"	"67.6"	"65.6"	"154.2"	"139.4"	"90.3"	"138.6"	"170.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A6NNM8"	"Tubulin polyglutamylase TTLL13P OS=Homo sapiens OX=9606 GN=TTLL13P PE=1 SV=2"	"2"	"1"	"1"	"1"	"815"	"93.6"	"8.91"	""	"2.13"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03133"	""	"ENSG00000213471"	"TTLL13"	"A6NNM8"	""	"Carboxyterminal post-translational modifications of tubulin"	"1"	"0"	"24.8"	"20.7"	"25.2"	"32.7"	"26.7"	"29.2"	"33.7"	"32.4"	"19.3"	"31.7"	"64.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07311"	"Acylphosphatase-1 OS=Homo sapiens OX=9606 GN=ACYP1 PE=1 SV=2"	"7"	"1"	"2"	"1"	"99"	"11.3"	"9.31"	"241.49"	"2.13"	"1"	"1"	"other metabolic processes"	""	"other molecular function"	"Pf00708"	"97"	"ENSG00000119640"	"ACYP1"	"A6NDV8; B2R590; hsa:97; P07311"	""	""	"0"	"0"	"124.1"	"122.3"	"177.5"	"101.1"	"143.4"	"110.0"	"159.1"	"170.3"	"127.7"	"206.7"	"347.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14324"	"Farnesyl pyrophosphate synthase OS=Homo sapiens OX=9606 GN=FDPS PE=1 SV=4"	"2"	"1"	"2"	"1"	"419"	"48.2"	"6.15"	"270.83"	"2.13"	"1"	"1"	"other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00348"	"2224"	"ENSG00000160752"	"FDPS"	"D3DV91; E9PCI9; hsa:2224; P14324; Q96G29"	"Cholesterol biosynthesis pathway; Sterol regulatory element-binding proteins (SREBP) signaling; Mevalonate pathway; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Cholesterol synthesis disorders; Cholesterol metabolism; Enterocyte cholesterol metabolism"	"Activation of gene expression by SREBF (SREBP); Cholesterol biosynthesis"	"9"	"0"	"13.9"	"10.9"	"15.6"	"8.2"	"13.5"	"11.0"	"12.9"	"7.4"	"6.5"	"16.7"	"17.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25325"	"3-mercaptopyruvate sulfurtransferase OS=Homo sapiens OX=9606 GN=MPST PE=1 SV=3"	"6"	"2"	"2"	"1"	"297"	"33.2"	"6.60"	"251.23"	"2.13"	"1"	"1"	"other metabolic processes;developmental processes;other biological processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00581"	"4357"	"ENSG00000128309"	"MPST"	"A8MZ34; B3KP52; hsa:4357; J3KPV7; O75750; P25325; Q6FHN9"	"Trans-sulfuration pathway; Amino acid metabolism"	"Degradation of cysteine and homocysteine"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q32P41"	"tRNA (guanine(37)-N1)-methyltransferase OS=Homo sapiens OX=9606 GN=TRMT5 PE=1 SV=2"	"2"	"1"	"1"	"1"	"509"	"58.2"	"8.62"	""	"2.12"	""	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"62.1"	"25.8"	"32.7"	"35.4"	"45.9"	"42.3"	"107.0"	"96.6"	"61.1"	"114.4"	"197.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BVS5"	"tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=TRMT61B PE=1 SV=2"	"3"	"1"	"2"	"1"	"477"	"52.9"	"6.62"	"239.77"	"2.12"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf08704"	"55006"	"ENSG00000171103"	"TRMT61B"	"hsa:55006; Q9BVS5; Q9H0Q9; Q9NWS7"	""	"tRNA modification in the mitochondrion"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16514"	"Transcription initiation factor TFIID subunit 12 OS=Homo sapiens OX=9606 GN=TAF12 PE=1 SV=1"	"7"	"1"	"1"	"1"	"161"	"17.9"	"7.99"	""	"2.12"	""	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03847"	"6883"	"ENSG00000120656"	"TAF12"	"D3DPM5; hsa:6883; Q15775; Q16514; Q5T077"	"Eukaryotic transcription initiation"	"HATs acetylate histones; Regulation of TP53 Activity through Phosphorylation; RNA Polymerase II Pre-transcription Events; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation"	"11"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N1G2"	"Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 OS=Homo sapiens OX=9606 GN=CMTR1 PE=1 SV=1"	"1"	"1"	"1"	"1"	"835"	"95.3"	"7.05"	""	"2.12"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01585, Pf01728"	"23070"	"ENSG00000137200"	"CMTR1"	"A8K949; hsa:23070; Q14670; Q8N1G2; Q96FJ9"	""	""	"0"	"0"	"26.6"	"17.1"	"24.4"	"25.5"	"30.1"	"23.1"	"58.1"	"55.8"	"48.6"	"72.9"	"71.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75592"	"E3 ubiquitin-protein ligase MYCBP2 OS=Homo sapiens OX=9606 GN=MYCBP2 PE=1 SV=4"	"0"	"1"	"2"	"1"	"4678"	"513.3"	"7.02"	"234.46"	"2.12"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00415, Pf03256, Pf08005, Pf08239, Pf13540, Pf13639"	"23077"	"ENSG00000005810"	"MYCBP2"	"A6NJC6; hsa:23077; O75592; Q5JSX8; Q5VZN6; Q6PIB6; Q9UQ11; Q9Y6E4"	"3q29 copy number variation syndrome"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96QK1"	"Vacuolar protein sorting-associated protein 35 OS=Homo sapiens OX=9606 GN=VPS35 PE=1 SV=2"	"1"	"1"	"2"	"1"	"796"	"91.6"	"5.49"	"240.02"	"2.11"	"1"	"1"	"cell-cell signaling;cell organization and biogenesis;transport;signal transduction;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding"	"Pf03635"	"55737"	"ENSG00000069329"	"VPS35"	"hsa:55737; Q561W2; Q96QK1; Q9H016; Q9H096; Q9H4P3; Q9H8J0; Q9NRS7; Q9NVG2; Q9NX80; Q9NZK2"	""	"WNT ligand biogenesis and trafficking"	"1"	"0"	"66.1"	"51.1"	"90.8"	"55.4"	"76.6"	"65.4"	"118.3"	"130.5"	"100.5"	"152.7"	"196.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T2D3"	"OTU domain-containing protein 3 OS=Homo sapiens OX=9606 GN=OTUD3 PE=1 SV=1"	"2"	"1"	"1"	"1"	"398"	"45.1"	"8.29"	""	"2.11"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf02338"	"23252"	"ENSG00000169914"	"OTUD3"	"hsa:23252; O75047; Q5T2D3"	""	"Ovarian tumor domain proteases; Regulation of PTEN stability and activity"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00308"	"NEDD4-like E3 ubiquitin-protein ligase WWP2 OS=Homo sapiens OX=9606 GN=WWP2 PE=1 SV=2"	"2"	"2"	"2"	"1"	"870"	"98.9"	"7.12"	"272.64"	"2.11"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00397, Pf00632"	"11060"	"ENSG00000198373"	"WWP2"	"A6NEP1; B2R706; B4DTL5; F5H213; H3BRF3; hsa:11060; I3RSG8; O00308; Q6ZTQ5; Q96CZ2; Q9BWN6"	""	"RHOQ GTPase cycle; Regulation of PTEN stability and activity; RHOJ GTPase cycle; NOTCH3 Activation and Transmission of Signal to the Nucleus; RHOU GTPase cycle"	"5"	"1"	"24.2"	"17.0"	"27.6"	"29.9"	"28.9"	"27.3"	"51.9"	"54.2"	"44.0"	"73.0"	"76.7"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92785"	"Zinc finger protein ubi-d4 OS=Homo sapiens OX=9606 GN=DPF2 PE=1 SV=2"	"3"	"1"	"1"	"1"	"391"	"44.1"	"6.33"	""	"2.11"	""	"1"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00628, Pf14051"	"5977"	"ENSG00000133884"	"DPF2"	"A8K7C9; B4DT58; hsa:5977; Q92785"	"Tumor suppressor activity of SMARCB1"	""	"1"	"0"	"45.3"	"27.9"	"44.7"	"46.5"	"41.9"	"44.8"	"78.9"	"70.3"	"53.1"	"80.3"	"105.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P36551"	"Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3"	"2"	"1"	"2"	"1"	"454"	"50.1"	"8.25"	"302.85"	"2.11"	"1"	"1"	"other metabolic processes;other biological processes"	"other membranes;cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf01218"	"1371"	"ENSG00000080819"	"CPOX"	"A8K275; B4DSD5; hsa:1371; P36551; Q14060; Q53F08; Q8IZ45; Q96AF3"	"Hemesynthesis defects and porphyrias; Heme biosynthesis"	"Heme biosynthesis"	"3"	"0"	"35.0"	"22.5"	"33.3"	"24.8"	"28.0"	"25.1"	"51.2"	"46.2"	"34.1"	"56.3"	"80.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N594"	"MPN domain-containing protein OS=Homo sapiens OX=9606 GN=MPND PE=1 SV=1"	"4"	"1"	"1"	"1"	"471"	"50.6"	"5.72"	""	"2.11"	""	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response"	"nucleus"	"other molecular function"	"Pf01398, Pf18755"	"84954"	"ENSG00000008382"	"MPND"	"hsa:84954; Q8N594; Q96SJ0; Q9Y2P1; Q9Y2P2"	""	""	"0"	"0"	"36.5"	"25.8"	"65.3"	"47.7"	"36.3"	"39.1"	"131.6"	"143.4"	"88.2"	"171.2"	"189.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12767"	"Transmembrane protein 94 OS=Homo sapiens OX=9606 GN=TMEM94 PE=1 SV=1"	"0"	"1"	"2"	"1"	"1356"	"151.1"	"6.44"	"234.99"	"2.11"	"1"	"1"	""	"other membranes"	""	""	"9772"	"ENSG00000177728"	"TMEM94"	"C9JL75; hsa:9772; O75536; Q12767; Q86XF1"	""	""	"0"	"0"	"6.0"	"7.1"	"8.5"	"5.6"	"7.1"	"5.3"	"40.4"	"121.5"	"145.0"	"225.5"	"301.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75665"	"Oral-facial-digital syndrome 1 protein OS=Homo sapiens OX=9606 GN=OFD1 PE=1 SV=1"	"1"	"1"	"1"	"1"	"1012"	"116.6"	"6.10"	""	"2.11"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf16045"	"8481"	"ENSG00000046651"	"OFD1"	"B9ZVU5; hsa:8481; O75665; O75666; Q4VAK4"	"Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Hedgehog 'off' state"	"11"	"0"	"336.8"	"251.0"	"372.0"	"258.6"	"372.7"	"374.9"	"606.2"	"513.5"	"418.6"	"598.5"	"754.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VZL5"	"Zinc finger MYM-type protein 4 OS=Homo sapiens OX=9606 GN=ZMYM4 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1548"	"172.7"	"6.84"	"266.94"	"2.10"	"1"	"1"	"cell organization and biogenesis;other biological processes"	""	"nucleic acid binding activity;other molecular function"	"Pf06467, Pf12012"	"9202"	"ENSG00000146463"	"ZMYM4"	"A0JP19; A0JP20; hsa:9202; O43308; Q5T5E1; Q5T5E2; Q5VZL5; Q7L3Q4"	""	""	"0"	"0"	"17.2"	"12.0"	"12.0"	"11.5"	"7.3"	"13.2"	"26.0"	"22.2"	"14.4"	"28.0"	"45.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11413"	"Glucose-6-phosphate 1-dehydrogenase OS=Homo sapiens OX=9606 GN=G6PD PE=1 SV=4"	"6"	"2"	"3"	"2"	"515"	"59.2"	"6.84"	"712.66"	"2.10"	"2"	"1"	"other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00479, Pf02781"	"2539"	"ENSG00000160211"	"G6PD"	"D3DWX9; hsa:2539; P11413; Q16000; Q16765; Q8IU70; Q8IU88; Q8IUA6; Q96PQ2"	"Glutathione metabolism; Pentose phosphate metabolism; Cori cycle; Vitamin D receptor pathway; Nuclear receptors meta-pathway; NRF2 pathway; ATM signaling in development and disease ; Metabolic reprogramming in colon cancer; Vitamin D-sensitive calcium signaling in depression; Pentose phosphate pathway in senescent cells; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Glycolysis in senescence; Sulfation biotransformation reaction"	"TP53 Regulates Metabolic Genes; NFE2L2 regulates pentose phosphate pathway genes; Pentose phosphate pathway"	"16"	"0"	"33.0"	"18.7"	"29.4"	"37.4"	"30.5"	"35.4"	"55.6"	"59.8"	"52.3"	"73.6"	"103.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6ZRY4"	"RNA-binding protein with multiple splicing 2 OS=Homo sapiens OX=9606 GN=RBPMS2 PE=1 SV=1"	"5"	"1"	"2"	"1"	"209"	"22.5"	"8.60"	"270.66"	"2.10"	"1"	"1"	"developmental processes;other biological processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"348093"	"ENSG00000166831"	"RBPMS2"	"A2RRG0; hsa:348093; Q6ZRY4"	""	""	"0"	"0"	"7.2"	"6.5"	"10.1"	"7.5"	"8.2"	"6.9"	"18.8"	"19.5"	"14.8"	"21.0"	"34.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NBJ5"	"Procollagen galactosyltransferase 1 OS=Homo sapiens OX=9606 GN=COLGALT1 PE=1 SV=1"	"1"	"1"	"2"	"1"	"622"	"71.6"	"7.31"	"289.67"	"2.10"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"ER/Golgi"	"other molecular function"	"Pf01755, Pf13704"	"79709"	"ENSG00000130309"	"COLGALT1"	"hsa:79709; Q8NBJ5; Q8NC64"	"Type I collagen synthesis in the context of osteogenesis imperfecta"	"Collagen biosynthesis and modifying enzymes"	"2"	"0"	"69.5"	"40.6"	"58.1"	"37.1"	"37.3"	"55.4"	"111.2"	"114.9"	"80.7"	"131.8"	"180.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NU22"	"Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2"	"0"	"1"	"2"	"1"	"5596"	"632.4"	"5.68"	"235.15"	"2.10"	"1"	"1"	"cell organization and biogenesis;transport"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07728, Pf17865, Pf17867"	"23195"	"ENSG00000112159; ENSG00000288121"	"MDN1"	"hsa:23195; O15019; Q5T794; Q9NU22"	""	""	"0"	"0"	"51.4"	"30.1"	"27.9"	"22.7"	"33.0"	"31.2"	"36.3"	"38.5"	"22.6"	"50.1"	"61.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82673"	"28S ribosomal protein S35, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS35 PE=1 SV=1"	"3"	"1"	"2"	"1"	"323"	"36.8"	"8.24"	"348.53"	"2.09"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf10213"	"60488"	"ENSG00000061794"	"MRPS35"	"hsa:60488; P82673; Q32LZ1; Q6P4C6; Q7L1M6; Q8NBP4; Q96AI0; Q9H044; Q9HC14; Q9P1R5"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T653"	"39S ribosomal protein L2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL2 PE=1 SV=2"	"4"	"1"	"2"	"1"	"305"	"33.3"	"11.30"	"283.20"	"2.09"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf00181, Pf03947"	"51069"	"ENSG00000112651"	"MRPL2"	"B2RC56; hsa:51069; Q5T653; Q8WUL1; Q96Q56; Q9Y311"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96AC1"	"Fermitin family homolog 2 OS=Homo sapiens OX=9606 GN=FERMT2 PE=1 SV=1"	"3"	"1"	"1"	"1"	"680"	"77.8"	"6.70"	""	"2.09"	""	"1"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00169, Pf00373, Pf18124"	"10979"	"ENSG00000073712"	"FERMT2"	"B5TJY2; hsa:10979; Q14840; Q86TY7; Q96AC1"	""	"RAC1 GTPase cycle; RAC3 GTPase cycle; Cell-extracellular matrix interactions"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P10619"	"Lysosomal protective protein OS=Homo sapiens OX=9606 GN=CTSA PE=1 SV=2"	"2"	"1"	"2"	"1"	"480"	"54.4"	"6.61"	"295.86"	"2.08"	"1"	"1"	"protein metabolism;transport;other biological processes"	"non-structural extracellular;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00450"	"5476"	"ENSG00000064601"	"CTSA"	"B2R798; hsa:5476; P10619; Q561W6; Q5JZH1; Q96KJ2; Q9BR08; Q9BW68"	"Ciliary landscape"	"MHC class II antigen presentation; Neutrophil degranulation; Glycosphingolipid metabolism; Sialic acid metabolism; Defective NEU1 causes sialidosis"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P38117"	"Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3"	"5"	"1"	"1"	"1"	"255"	"27.8"	"8.10"	""	"2.08"	""	"1"	"other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf01012"	"2109"	"ENSG00000105379"	"ETFB"	"A8K766; B3KNY2; hsa:2109; P38117; Q6IBH7; Q71RF6; Q9Y3S7"	""	"Respiratory electron transport; Protein methylation"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A0AVT1"	"Ubiquitin-like modifier-activating enzyme 6 OS=Homo sapiens OX=9606 GN=UBA6 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1052"	"117.9"	"6.14"	"259.78"	"2.08"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00899, Pf09358, Pf10585, Pf16190, Pf16191"	"55236"	"ENSG00000033178"	"UBA6"	"A0AVT1; A6N8M7; B2RAV3; hsa:55236; Q4W5K0; Q6UV21; Q86T78; Q86TC7; Q8N5T3; Q8N9E4; Q9H3T7; Q9NVC9"	""	"Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Antigen processing: Ubiquitination & Proteasome degradation"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22695"	"Cytochrome b-c1 complex subunit 2, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC2 PE=1 SV=3"	"2"	"1"	"2"	"1"	"453"	"48.4"	"8.63"	"234.59"	"2.08"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf00675, Pf05193"	"7385"	"ENSG00000140740"	"UQCRC2"	"B3KSN4; hsa:7385; P22695; Q9BQ05"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex III assembly"	"Respiratory electron transport"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UPW5"	"Cytosolic carboxypeptidase 1 OS=Homo sapiens OX=9606 GN=AGTPBP1 PE=1 SV=3"	"1"	"1"	"1"	"1"	"1226"	"138.4"	"6.15"	""	"2.08"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00246, Pf18027"	"23287"	"ENSG00000135049"	"AGTPBP1"	"B4DIT6; B4DRZ8; hsa:23287; Q5VV80; Q63HM7; Q658P5; Q6P9D6; Q9H8U6; Q9H9W8; Q9NVK1; Q9UPW5"	""	"Carboxyterminal post-translational modifications of tubulin"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00244"	"Copper transport protein ATOX1 OS=Homo sapiens OX=9606 GN=ATOX1 PE=1 SV=1"	"12"	"1"	"1"	"1"	"68"	"7.4"	"7.24"	""	"2.07"	""	"1"	"stress response;transport;other biological processes"	"cytosol"	"other molecular function"	"Pf00403"	"475"	"ENSG00000177556"	"ATOX1"	"A8KAJ8; D3DQI2; hsa:475; O00244; Q2M1R6; Q56AP3"	"Copper homeostasis"	"Detoxification of Reactive Oxygen Species; Ion influx/efflux at host-pathogen interface"	"3"	"0"	"18.4"	"10.4"	"23.0"	"19.1"	"34.2"	"32.1"	"39.9"	"34.4"	"19.0"	"50.3"	"51.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16763"	"Ubiquitin-conjugating enzyme E2 S OS=Homo sapiens OX=9606 GN=UBE2S PE=1 SV=2"	"7"	"1"	"2"	"1"	"222"	"23.8"	"8.38"	"249.21"	"2.07"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00179"	"27338"	"ENSG00000108106"	"UBE2S"	"hsa:27338; Q16763; Q9BTC1"	""	"Senescence-Associated Secretory Phenotype (SASP); Antigen processing: Ubiquitination & Proteasome degradation; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Separation of Sister Chromatids; CDK-mediated phosphorylation and removal of Cdc6; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of Cyclin B; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; Regulation of APC/C activators between G1/S and early anaphase; Phosphorylation of the APC/C; APC-Cdc20 mediated degradation of Nek2A; Transcriptional Regulation by VENTX; Aberrant regulation of mitotic exit in cancer due to RB1 defects"	"19"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52333"	"Tyrosine-protein kinase JAK3 OS=Homo sapiens OX=9606 GN=JAK3 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1124"	"125.0"	"7.18"	"289.47"	"2.07"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cytoplasmic organelle"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf07714, Pf17887, Pf18377, Pf18379"	"3718"	"ENSG00000105639"	"JAK3"	"hsa:3718; P52333; Q13259; Q13260; Q13611; Q8N1E8; Q99699; Q9Y6S2"	"IL-7 signaling pathway; IL-9 signaling pathway; Oncostatin M signaling pathway; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; IL-4 signaling pathway; PI3K-Akt signaling pathway; Non-small cell lung cancer; ncRNAs involved in STAT3 signaling in hepatocellular carcinoma; Measles virus infection; Hepatitis B infection; IL-2 signaling pathway"	"Potential therapeutics for SARS; RAF/MAP kinase cascade; Interleukin receptor SHC signaling; Interleukin-7 signaling; Signaling by ALK; Interleukin-4 and Interleukin-13 signaling; Interleukin-20 family signaling; Interleukin-2 signaling; Interleukin-15 signaling; Interleukin-9 signaling; Interleukin-21 signaling"	"23"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P4I2"	"WD repeat-containing protein 73 OS=Homo sapiens OX=9606 GN=WDR73 PE=1 SV=1"	"2"	"1"	"2"	"1"	"378"	"41.7"	"5.78"	"250.33"	"2.07"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton"	""	""	"84942"	"ENSG00000177082"	"WDR73"	"hsa:84942; Q6P4I2; Q96JZ1; Q9P0B7"	"Nephrotic syndrome; 15q25 copy number variation"	""	"2"	"0"	"118.2"	"64.1"	"76.3"	"100.7"	"80.1"	"93.0"	"134.0"	"144.6"	"91.2"	"128.2"	"156.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13356"	"RING-type E3 ubiquitin-protein ligase PPIL2 OS=Homo sapiens OX=9606 GN=PPIL2 PE=1 SV=1"	"3"	"2"	"2"	"2"	"520"	"58.8"	"8.78"	"236.03"	"2.07"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00160"	"23759"	"ENSG00000100023"	"PPIL2"	"hsa:23759; Q13356; Q13357; Q8TAH2; Q9BWR8"	""	"mRNA Splicing - Major Pathway; Basigin interactions"	"2"	"0"	"12.5"	"6.7"	"15.0"	"18.5"	"14.1"	"19.0"	"27.2"	"29.3"	"27.0"	"35.5"	"70.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00255"	"Menin OS=Homo sapiens OX=9606 GN=MEN1 PE=1 SV=4"	"2"	"1"	"2"	"1"	"615"	"68.0"	"6.55"	"239.61"	"2.07"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05053"	"4221"	"ENSG00000133895"	"MEN1"	"A5HBC6; A5HBC7; A5HBC8; A5HBC9; A5HBD0; A5HBD1; A5HBD2; hsa:4221; O00255; O00632; Q9BUF0; Q9BUK2"	"10q11.21q11.23 copy number variation syndrome"	"RHO GTPases activate IQGAPs; Formation of WDR5-containing histone-modifying complexes; Formation of the beta-catenin:TCF transactivating complex; SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Deactivation of the beta-catenin transactivating complex; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation"	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96FS4"	"Signal-induced proliferation-associated protein 1 OS=Homo sapiens OX=9606 GN=SIPA1 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1042"	"112.1"	"6.60"	"258.74"	"2.07"	"1"	"1"	"cell organization and biogenesis;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity"	"Pf00595, Pf02145"	"6494"	"ENSG00000213445"	"SIPA1"	"hsa:6494; O14518; O60484; O60618; Q2YD83; Q96FS4"	"MAPK cascade"	"Rap1 signalling"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46939"	"Utrophin OS=Homo sapiens OX=9606 GN=UTRN PE=1 SV=2"	"0"	"1"	"1"	"1"	"3433"	"394.2"	"5.33"	""	"2.07"	""	"1"	"cell-cell signaling;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00307, Pf00435, Pf00569, Pf09068, Pf09069"	"7402"	"ENSG00000152818"	"UTRN"	"hsa:7402; P46939; Q5SYY1; Q5SZ57; Q9UJ40"	"Primary focal segmental glomerulosclerosis (FSGS)"	"EGR2 and SOX10-mediated initiation of Schwann cell myelination"	"2"	"0"	"19.5"	"16.0"	"18.5"	"17.1"	"13.8"	"25.9"	"32.0"	"35.8"	"23.5"	"38.9"	"46.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P21333"	"Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4"	"0"	"1"	"2"	"1"	"2647"	"280.6"	"6.06"	"233.44"	"2.07"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00307, Pf00630"	"2316"	"ENSG00000196924"	"FLNA"	"E9KL45; hsa:2316; P21333; Q5HY53; Q5HY55; Q8NF52"	"Androgen receptor signaling pathway; Prolactin signaling pathway; Focal adhesion; Hypothesized pathways in pathogenesis of cardiovascular disease; MAPK signaling pathway; IL-4 signaling pathway; Ebola virus infection in host; Joubert syndrome; NPHP1 deletion syndrome"	"OAS antiviral response; Platelet degranulation ; RHO GTPases activate PAKs; GP1b-IX-V activation signalling; Cell-extracellular matrix interactions"	"14"	"0"	"73.5"	"35.1"	"60.3"	"58.5"	"62.0"	"65.8"	"127.3"	"128.4"	"75.2"	"116.2"	"190.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A6NEE1"	"Pleckstrin homology domain-containing family D member 1 OS=Homo sapiens OX=9606 GN=PLEKHD1 PE=2 SV=3"	"2"	"1"	"1"	"1"	"506"	"59.2"	"6.44"	""	"2.07"	""	"1"	""	""	""	"Pf00169"	"400224"	"ENSG00000175985"	"PLEKHD1"	"A6NEE1; B9EJC2; hsa:400224"	""	""	"0"	"0"	"91.4"	"68.2"	"98.2"	"82.9"	"96.4"	"127.9"	"174.4"	"151.5"	"103.9"	"189.9"	"213.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14517"	"Protocadherin Fat 1 OS=Homo sapiens OX=9606 GN=FAT1 PE=1 SV=2"	"0"	"1"	"2"	"1"	"4588"	"506.0"	"5.00"	"235.09"	"2.07"	"1"	"1"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00008, Pf00028, Pf02210"	"2195"	"ENSG00000083857"	"FAT1"	"hsa:2195; Q14517"	"Primary focal segmental glomerulosclerosis (FSGS); Head and neck squamous cell carcinoma"	""	"2"	"0"	"28.2"	"17.8"	"26.8"	"33.2"	"39.3"	"37.2"	"121.8"	"110.0"	"79.0"	"108.4"	"133.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N1B4"	"Vacuolar protein sorting-associated protein 52 homolog OS=Homo sapiens OX=9606 GN=VPS52 PE=1 SV=1"	"2"	"1"	"2"	"1"	"723"	"82.2"	"5.99"	"250.93"	"2.07"	"1"	"1"	"transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf04129"	"6293"	"ENSG00000206286; ENSG00000223501; ENSG00000224455; ENSG00000225590; ENSG00000228425; ENSG00000236014"	"VPS52"	"A2BF38; B0UZZ4; B4DNI9; hsa:6293; Q53GR4; Q5JPA0; Q5SQW1; Q8IUN6; Q8N1B4; Q9NPT5"	""	"Retrograde transport at the Trans-Golgi-Network"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86U38"	"Nucleolar protein 9 OS=Homo sapiens OX=9606 GN=NOP9 PE=1 SV=1"	"3"	"2"	"2"	"1"	"636"	"69.4"	"7.28"	"283.30"	"2.07"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;transport"	"nucleus;other cell component"	""	""	"161424"	"ENSG00000196943; ENSG00000285326"	"NOP9"	"A8MY76; hsa:161424; Q86U38; Q8IVF0; Q8TBS6"	""	""	"0"	"0"	"5.9"	"5.8"	"8.3"	"6.4"	"5.7"	"7.2"	"15.1"	"16.1"	"9.0"	"14.7"	"20.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95644"	"Nuclear factor of activated T-cells, cytoplasmic 1 OS=Homo sapiens OX=9606 GN=NFATC1 PE=1 SV=3"	"1"	"1"	"2"	"1"	"943"	"101.2"	"6.99"	"252.80"	"2.06"	"1"	"1"	"developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00554, Pf16179"	"4772"	"ENSG00000131196"	"NFATC1"	"B5B2M4; B5B2M5; B5B2M6; B5B2M7; B5B2M8; B5B2M9; B5B2N1; hsa:4772; O95644; Q12865; Q15793; Q2M1S3"	"Heart development; RANKL/RANK signaling pathway; Ectoderm differentiation; Initiation of transcription and translation elongation at the HIV-1 LTR; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Wnt signaling; Vitamin D in inflammatory diseases; Cancer immunotherapy by PD-1 blockade; Hepatitis B infection; Th17 cell differentiation pathway; DYRK1A involvement regarding cell proliferation in brain development; Inflammatory bowel disease signaling; Clock-controlled autophagy in bone metabolism; IL-26 signaling pathways; T-cell receptor signaling pathway"	"FCERI mediated Ca+2 mobilization; Ca2+ pathway; CLEC7A (Dectin-1) induces NFAT activation; Calcineurin activates NFAT"	"20"	"0"	"83.2"	"45.4"	"70.7"	"64.0"	"70.7"	"85.2"	"111.6"	"101.1"	"72.5"	"122.4"	"192.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HC35"	"Echinoderm microtubule-associated protein-like 4 OS=Homo sapiens OX=9606 GN=EML4 PE=1 SV=3"	"1"	"1"	"2"	"1"	"981"	"108.8"	"6.40"	"312.11"	"2.06"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf03451, Pf07714"	"27436"	"ENSG00000143924"	"EML4"	"A6H8Y6; A6P4T4; A6P4V4; B2RBK3; B2RTW7; B5MCW9; hsa:27436; Q3SWW0; Q53R29; Q53TW8; Q6PJ45; Q9HC35; Q9NV40"	"Non-small cell lung cancer"	"EML4 and NUDC in mitotic spindle formation; ALK mutants bind TKIs; Nuclear events stimulated by ALK signaling in cancer"	"5"	"0"	"29.3"	"20.5"	"23.9"	"18.3"	"23.0"	"30.8"	"65.3"	"54.6"	"44.3"	"52.9"	"72.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y490"	"Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3"	"0"	"1"	"2"	"1"	"2541"	"269.6"	"6.07"	"275.91"	"2.06"	"1"	"1"	"cell adhesion;cell organization and biogenesis;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00373, Pf01608, Pf08913, Pf09141, Pf16511"	"7094"	"ENSG00000137076"	"TLN1"	"A6NMY0; hsa:7094; Q86YD0; Q9NZQ2; Q9UHH8; Q9UPX3; Q9Y490"	"Integrin-mediated cell adhesion; Primary focal segmental glomerulosclerosis (FSGS); Focal adhesion; TROP2 regulatory signaling"	"Platelet degranulation ; Signaling by BRAF and RAF1 fusions; XBP1(S) activates chaperone genes; SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion; Smooth Muscle Contraction; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; GRB2:SOS provides linkage to MAPK signaling for Integrins ; p130Cas linkage to MAPK signaling for integrins"	"18"	"0"	"40.4"	"16.8"	"23.3"	"28.0"	"24.8"	"32.6"	"167.6"	"138.9"	"128.2"	"294.5"	"615.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NUV9"	"GTPase IMAP family member 4 OS=Homo sapiens OX=9606 GN=GIMAP4 PE=1 SV=1"	"2"	"1"	"1"	"1"	"329"	"37.5"	"7.81"	""	"2.06"	""	"1"	""	"cytosol;other cell component"	"other molecular function"	"Pf04548"	"55303"	"ENSG00000133574"	"GIMAP4"	"hsa:55303; Q9NUV9"	""	""	"0"	"0"	"20.8"	"10.3"	"18.5"	"23.9"	"24.1"	"30.9"	"172.3"	"162.7"	"157.1"	"287.4"	"473.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00536"	"Cyclin-dependent kinase 16 OS=Homo sapiens OX=9606 GN=CDK16 PE=1 SV=1"	"3"	"1"	"1"	"1"	"496"	"55.7"	"7.62"	""	"2.06"	""	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"5127"	"ENSG00000102225"	"CDK16"	"A8K280; B7Z7C8; hsa:5127; J3KN74; J3KQP7; Q00536"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13613"	"Myotubularin-related protein 1 OS=Homo sapiens OX=9606 GN=MTMR1 PE=1 SV=4"	"1"	"1"	"1"	"1"	"665"	"74.6"	"7.14"	""	"2.06"	""	"1"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf02893, Pf06602"	"8776"	"ENSG00000063601"	"MTMR1"	"A0A024RC07; hsa:8776; Q13613; Q9UBX6; Q9UEM0; Q9UQD5"	""	"RHOF GTPase cycle; Synthesis of PIPs at the plasma membrane"	"2"	"0"	"18.9"	"13.9"	"21.8"	"23.0"	"25.4"	"25.2"	"44.4"	"41.9"	"37.4"	"63.1"	"65.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86VF2"	"Immunoglobulin-like and fibronectin type III domain-containing protein 1 OS=Homo sapiens OX=9606 GN=IGFN1 PE=1 SV=2"	"1"	"1"	"1"	"1"	"1251"	"137.7"	"7.56"	""	"2.06"	""	"1"	""	"cytoskeleton;nucleus"	""	"Pf00041, Pf07679, Pf18362"	"91156"	"ENSG00000163395"	"IGFN1"	"F8WAI1; hsa:91156; Q86VF2; Q9NT72"	""	""	"0"	"0"	"294.7"	"177.6"	"267.5"	"238.0"	"214.6"	"245.7"	"489.7"	"405.7"	"259.8"	"350.3"	"521.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z2Y5"	"Nik-related protein kinase OS=Homo sapiens OX=9606 GN=NRK PE=1 SV=2"	"1"	"1"	"1"	"1"	"1582"	"178.4"	"6.33"	""	"2.06"	""	"1"	"protein metabolism;other metabolic processes"	""	"kinase activity;other molecular function"	"Pf00069, Pf00780"	"203447"	"ENSG00000123572"	"NRK"	"hsa:203447; Q32ND6; Q5H9K2; Q6ZMP2; Q7Z2Y5"	"NAD+ metabolism"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00154"	"Cytosolic acyl coenzyme A thioester hydrolase OS=Homo sapiens OX=9606 GN=ACOT7 PE=1 SV=3"	"3"	"1"	"2"	"1"	"380"	"41.8"	"8.54"	"239.13"	"2.06"	"1"	"1"	"other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf03061"	"11332"	"ENSG00000097021"	"ACOT7"	"A8K0K7; A8K232; A8K6B8; A8K837; B3KQ12; hsa:11332; O00154; O43703; Q53Y78; Q5JYL2; Q5JYL3; Q5JYL4; Q5JYL5; Q5JYL6; Q5TGR4; Q9UJM9; Q9Y539; Q9Y540"	""	"Mitochondrial Fatty Acid Beta-Oxidation"	"1"	"0"	"17.8"	"12.3"	"12.3"	"16.5"	"13.9"	"16.7"	"24.3"	"16.6"	"21.5"	"32.7"	"54.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBQ7"	"Glyoxylate reductase/hydroxypyruvate reductase OS=Homo sapiens OX=9606 GN=GRHPR PE=1 SV=1"	"3"	"1"	"2"	"1"	"328"	"35.6"	"7.39"	"260.49"	"2.06"	"1"	"1"	"other metabolic processes"	"cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00389, Pf02826"	"9380"	"ENSG00000137106"	"GRHPR"	"hsa:9380; Q5T945; Q9H3E9; Q9H636; Q9UBQ7; Q9UKX1"	""	"Glyoxylate metabolism and glycine degradation"	"1"	"0"	"34.0"	"27.3"	"39.0"	"32.2"	"33.8"	"48.5"	"64.1"	"85.9"	"80.3"	"162.1"	"213.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6KC79"	"Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2"	"0"	"1"	"1"	"1"	"2804"	"315.9"	"7.91"	""	"2.06"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf12765, Pf12830"	"25836"	"ENSG00000164190"	"NIPBL"	"hsa:25836; Q6KC79; Q6KCD6; Q6N080; Q6ZT92; Q7Z2E6; Q8N4M5; Q9Y6Y3; Q9Y6Y4"	"Cohesin complex - Cornelia de Lange syndrome; NIPBL role in DNA damage - Cornelia de Lange syndrome"	"Cohesin Loading onto Chromatin"	"3"	"0"	"5.1"	"5.1"	"6.8"	"4.6"	"5.2"	"10.3"	"19.3"	"18.2"	"13.4"	"23.7"	"29.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VSY0"	"G kinase-anchoring protein 1 OS=Homo sapiens OX=9606 GN=GKAP1 PE=1 SV=2"	"2"	"1"	"1"	"1"	"366"	"42.1"	"8.82"	""	"2.06"	""	"1"	"signal transduction;other biological processes"	"ER/Golgi"	"other molecular function"	""	"80318"	"ENSG00000165113"	"GKAP1"	"hsa:80318; Q5VSY0; Q96LI0; Q9BYI1; Q9BYI2; Q9H225"	""	""	"0"	"0"	"66.7"	"31.6"	"82.7"	"73.7"	"73.0"	"48.8"	"86.5"	"76.7"	"61.3"	"104.5"	"188.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92882"	"Osteoclast-stimulating factor 1 OS=Homo sapiens OX=9606 GN=OSTF1 PE=1 SV=2"	"6"	"1"	"2"	"1"	"214"	"23.8"	"5.68"	"352.25"	"2.05"	"1"	"1"	"signal transduction;other biological processes"	"other cell component"	"other molecular function"	"Pf00018, Pf12796"	"26578"	"ENSG00000134996"	"OSTF1"	"hsa:26578; Q5W126; Q92882; Q96IJ4"	""	"Neutrophil degranulation"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18031"	"Tyrosine-protein phosphatase non-receptor type 1 OS=Homo sapiens OX=9606 GN=PTPN1 PE=1 SV=1"	"3"	"1"	"1"	"1"	"435"	"49.9"	"6.27"	""	"2.05"	""	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"other membranes;cytosol;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00102"	"5770"	"ENSG00000196396"	"PTPN1"	"hsa:5770; P18031; Q5TGD8; Q9BQV9; Q9NQQ4"	"Leptin signaling pathway; Prolactin signaling pathway; Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4); VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Insulin signaling"	"Insulin receptor recycling; Growth hormone receptor signaling; Regulation of IFNG signaling; Regulation of IFNA/IFNB signaling; Negative regulation of MET activity; Integrin signaling; MECP2 regulates neuronal receptors and channels; PTK6 Down-Regulation"	"14"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9GZZ8"	"Extracellular glycoprotein lacritin OS=Homo sapiens OX=9606 GN=LACRT PE=1 SV=1"	"8"	"1"	"1"	"1"	"138"	"14.2"	"5.50"	""	"2.04"	""	"1"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"non-structural extracellular;other cell component"	"signal transduction activity or receptor binding;other molecular function"	""	"90070"	"ENSG00000135413"	"LACRT"	"hsa:90070; Q9GZZ8"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43598"	"2'-deoxynucleoside 5'-phosphate N-hydrolase 1 OS=Homo sapiens OX=9606 GN=DNPH1 PE=1 SV=1"	"6"	"1"	"2"	"1"	"174"	"19.1"	"5.05"	"282.66"	"2.04"	"1"	"1"	"other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf05014"	"10591"	"ENSG00000112667"	"DNPH1"	"B2LUJ9; hsa:10591; O43598"	""	"Purine catabolism"	"1"	"0"	"16.7"	"14.6"	"23.2"	"8.9"	"20.7"	"16.2"	"15.7"	"10.8"	"9.8"	"23.8"	"26.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42356"	"Phosphatidylinositol 4-kinase alpha OS=Homo sapiens OX=9606 GN=PI4KA PE=1 SV=4"	"1"	"1"	"1"	"1"	"2102"	"236.7"	"7.06"	""	"2.04"	""	"1"	"other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"kinase activity;other molecular function"	"Pf00454, Pf00613, Pf19274"	"5297"	"ENSG00000241973"	"PI4KA"	"hsa:5297; P42356; Q7Z625; Q9UPG2"	"Ectoderm differentiation; 22q11.2 copy number variation syndrome"	"Synthesis of PIPs at the Golgi membrane; Synthesis of PIPs at the ER membrane"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q09666"	"Neuroblast differentiation-associated protein AHNAK OS=Homo sapiens OX=9606 GN=AHNAK PE=1 SV=2"	"1"	"1"	"2"	"1"	"5890"	"628.7"	"6.15"	""	"2.04"	""	"1"	"other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	""	"79026"	"ENSG00000124942"	"AHNAK"	"A1A586; hsa:79026; Q09666"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15349"	"Ribosomal protein S6 kinase alpha-2 OS=Homo sapiens OX=9606 GN=RPS6KA2 PE=1 SV=2"	"3"	"1"	"1"	"1"	"733"	"83.2"	"8.68"	""	"2.04"	""	"1"	"cell-cell signaling;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00433"	"6196"	"ENSG00000071242"	"RPS6KA2"	"B3KTK9; hsa:6196; Q15349; Q15419; Q59GJ3; Q5TI68; Q96J38; Q9UJN5"	"Prolactin signaling pathway; Angiopoietin-like protein 8 regulatory pathway; Thermogenesis; EGF/EGFR signaling pathway; Translation inhibitors in chronically activated PDGFRA cells; Cytoplasmic ribosomal proteins; Insulin signaling; Host-pathogen interaction of human coronaviruses - MAPK signaling"	"Recycling pathway of L1; Senescence-Associated Secretory Phenotype (SASP); RSK activation; ERK/MAPK targets; CREB phosphorylation; Gastrin-CREB signalling pathway via PKC and MAPK"	"15"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H267"	"Vacuolar protein sorting-associated protein 33B OS=Homo sapiens OX=9606 GN=VPS33B PE=1 SV=2"	"2"	"1"	"2"	"1"	"617"	"70.5"	"6.71"	"408.21"	"0.00"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00995"	"26276"	"ENSG00000184056"	"VPS33B"	"B3KQF6; hsa:26276; Q96K14; Q9H267; Q9NRP6; Q9NSF3"	""	"Prevention of phagosomal-lysosomal fusion; SARS-CoV-2 modulates autophagy"	"2"	"0"	"4.9"	"4.9"	"7.2"	"5.7"	"8.2"	"4.9"	"14.5"	"18.2"	"6.9"	"14.3"	"21.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00461"	"Golgi integral membrane protein 4 OS=Homo sapiens OX=9606 GN=GOLIM4 PE=1 SV=1"	"2"	"1"	"2"	"1"	"696"	"81.8"	"4.77"	"276.43"	"0.00"	"1"	"1"	""	"other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	""	""	"27333"	"ENSG00000173905"	"GOLIM4"	"hsa:27333; O00461"	""	"Intra-Golgi traffic"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NVP1"	"ATP-dependent RNA helicase DDX18 OS=Homo sapiens OX=9606 GN=DDX18 PE=1 SV=2"	"4"	"2"	"2"	"2"	"670"	"75.4"	"9.50"	"259.00"	"0.00"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271, Pf13959"	"8886"	"ENSG00000088205"	"DDX18"	"hsa:8886; Q6GTZ9; Q6IAU4; Q92732; Q9BQB7; Q9NVP1"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UL51"	"Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 OS=Homo sapiens OX=9606 GN=HCN2 PE=1 SV=3"	"4"	"1"	"1"	"1"	"889"	"96.9"	"8.97"	""	"0.00"	""	"1"	"cell-cell signaling;transport;other biological processes"	"plasma membrane;other membranes;other cell component"	"transporter activity;other molecular function"	"Pf00027, Pf00520, Pf08412"	"610"	"ENSG00000099822"	"HCN2"	"hsa:610; O60742; O60743; O75267; Q9UBS2; Q9UL51"	"Genes targeted by miRNAs in adipocytes"	"HCN channels"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5TB80"	"Centrosomal protein of 162 kDa OS=Homo sapiens OX=9606 GN=CEP162 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1403"	"161.8"	"5.47"	""	"0.00"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis"	"cytosol;cytoskeleton;nucleus"	""	""	"22832"	"ENSG00000135315"	"CEP162"	"A6PVL7; A6PVL8; hsa:22832; Q5TB80; Q6P475; Q9Y2L2"	"Genes related to primary cilium development (based on CRISPR)"	"Anchoring of the basal body to the plasma membrane"	"2"	"0"	"38.8"	"12.6"	"22.0"	"29.4"	"24.3"	"28.6"	"93.6"	"79.6"	"51.7"	"101.0"	"168.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08648"	"Integrin alpha-5 OS=Homo sapiens OX=9606 GN=ITGA5 PE=1 SV=2"	"5"	"1"	"1"	"1"	"1049"	"114.5"	"5.77"	""	"0.00"	""	"1"	"cell adhesion;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01839, Pf08441"	"3678"	"ENSG00000161638"	"ITGA5"	"hsa:3678; P08648; Q96HA5"	"Integrin-mediated cell adhesion; Arrhythmogenic right ventricular cardiomyopathy; Focal adhesion; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Ebola virus infection in host; Epithelial to mesenchymal transition in colorectal cancer; CCL18 signaling pathway; GDNF signaling; TROP2 regulatory signaling"	"Cell surface interactions at the vascular wall; Integrin cell surface interactions; GPER1 signaling; Signal transduction by L1; RUNX2 regulates genes involved in cell migration; Fibronectin matrix formation; Elastic fibre formation"	"17"	"0"	"10.3"	"5.3"	"6.5"	"6.9"	"9.2"	"9.8"	"16.3"	"9.0"	"6.3"	"19.1"	"20.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25490"	"Transcriptional repressor protein YY1 OS=Homo sapiens OX=9606 GN=YY1 PE=1 SV=2"	"9"	"4"	"4"	"4"	"414"	"44.7"	"6.25"	"1129.76"	""	"4"	""	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00096"	"7528"	"ENSG00000100811"	"YY1"	"hsa:7528; P25490; Q14935"	"Sterol regulatory element-binding proteins (SREBP) signaling; Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4); Pleural mesothelioma"	"Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; UCH proteinases; DNA Damage Recognition in GG-NER; TFAP2 (AP-2) family regulates transcription of growth factors and their receptors"	"8"	"0"	"394.3"	"196.5"	"172.8"	"302.5"	"268.2"	"352.6"	"1106.6"	"1018.1"	"636.9"	"1041.1"	"1275.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P45974"	"Ubiquitin carboxyl-terminal hydrolase 5 OS=Homo sapiens OX=9606 GN=USP5 PE=1 SV=2"	"3"	"2"	"2"	"2"	"858"	"95.7"	"5.03"	"1105.44"	""	"2"	""	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf00443, Pf00627, Pf02148, Pf17807"	"8078"	"ENSG00000111667"	"USP5"	"D3DUS7; D3DUS8; hsa:8078; P45974; Q96J22"	"IL-18 signaling pathway"	"Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Ub-specific processing proteases"	"3"	"0"	"55.3"	"34.6"	"48.1"	"41.4"	"44.0"	"38.6"	"56.6"	"57.1"	"51.2"	"67.8"	"113.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P43155"	"Carnitine O-acetyltransferase OS=Homo sapiens OX=9606 GN=CRAT PE=1 SV=5"	"3"	"2"	"2"	"2"	"626"	"70.8"	"8.44"	"727.82"	""	"2"	""	"other metabolic processes"	"other membranes;cytosol;mitochondrion;ER/Golgi;other cytoplasmic organelle"	"other molecular function"	"Pf00755"	"1384"	"ENSG00000095321"	"CRAT"	"P43155; Q5T952; Q9BW16"	"Fatty acid beta-oxidation"	"Peroxisomal protein import; Beta-oxidation of pristanoyl-CoA"	"3"	"0"	"32.1"	"26.7"	"38.5"	"41.1"	"35.4"	"39.7"	"197.3"	"204.2"	"191.3"	"294.3"	"485.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99627"	"COP9 signalosome complex subunit 8 OS=Homo sapiens OX=9606 GN=COPS8 PE=1 SV=1"	"6"	"1"	"1"	"1"	"209"	"23.2"	"5.38"	"606.85"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf10075"	"10920"	"ENSG00000198612"	"COPS8"	"A8K1H6; hsa:10920; Q53QS9; Q99627"	"Ciliary landscape; 2q37 copy number variation syndrome"	"DNA Damage Recognition in GG-NER; Cargo recognition for clathrin-mediated endocytosis; Neddylation; Formation of TC-NER Pre-Incision Complex"	"6"	"0"	"52.3"	"29.9"	"46.7"	"43.7"	"40.6"	"45.5"	"71.6"	"65.2"	"47.9"	"91.0"	"114.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23258"	"Tubulin gamma-1 chain OS=Homo sapiens OX=9606 GN=TUBG1 PE=1 SV=2"	"6"	"2"	"2"	"2"	"451"	"51.1"	"6.14"	"581.13"	""	"2"	""	"cell cycle OR cell proliferation;cell organization and biogenesis"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00091, Pf03953"	"7283"	"ENSG00000131462"	"TUBG1"	"hsa:7283; P23258; Q53X79; Q9BW59"	"Alstrom syndrome"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"8"	"0"	"7.7"	"2.6"	"8.9"	"7.9"	"8.9"	"10.5"	"48.8"	"56.2"	"53.4"	"93.2"	"115.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82912"	"28S ribosomal protein S11, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS11 PE=1 SV=2"	"9"	"1"	"1"	"1"	"194"	"20.6"	"10.81"	"574.84"	""	"1"	""	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00411"	"64963"	"ENSG00000181991"	"MRPS11"	"B2RD52; hsa:64963; P82912; Q969D7; Q96GI3; Q9BYC3"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q71RC2"	"La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3"	"2"	"1"	"1"	"1"	"724"	"80.5"	"6.61"	"573.45"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity"	"Pf05383"	"113251"	"ENSG00000161813"	"LARP4"	"A8K6T1; E9PDG5; G3XAA8; G5E976; hsa:113251; Q5CZ97; Q6ZV14; Q71RC2; Q96NF9"	""	""	"0"	"0"	"14.9"	"7.2"	"13.9"	"11.3"	"10.5"	"17.4"	"25.1"	"30.1"	"19.3"	"24.3"	"19.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WVK2"	"U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP27 PE=1 SV=1"	"10"	"1"	"1"	"1"	"155"	"18.8"	"11.62"	"539.20"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf08648"	"11017"	"ENSG00000124380"	"SNRNP27"	"hsa:11017; Q15410; Q8WVK2"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"18.8"	"14.1"	"20.0"	"18.0"	"20.9"	"23.9"	"69.2"	"58.1"	"38.0"	"62.5"	"75.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60934"	"Nibrin OS=Homo sapiens OX=9606 GN=NBN PE=1 SV=1"	"2"	"1"	"1"	"1"	"754"	"84.9"	"6.90"	"535.94"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00498, Pf08599, Pf16508"	"4683"	"ENSG00000104320"	"NBN"	"B2R626; B2RNC5; hsa:4683; O60672; O60934; Q32NF7; Q53FM6; Q63HR6; Q7LDM2"	"miRNA regulation of DNA damage response; Homologous recombination; DDX1 as a regulatory component of the Drosha microprocessor; ATM signaling in development and disease ; Breast cancer pathway; DNA repair pathways, full network; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; Primary ovarian insufficiency; DNA damage response"	"Resolution of D-loop Structures through Holliday Junction Intermediates; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; Meiotic recombination; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; DNA Damage/Telomere Stress Induced Senescence; Nonhomologous End-Joining (NHEJ); HDR through MMEJ (alt-NHEJ); Sensing of DNA Double Strand Breaks"	"29"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96E29"	"Transcription termination factor 3, mitochondrial OS=Homo sapiens OX=9606 GN=MTERF3 PE=1 SV=2"	"3"	"1"	"1"	"1"	"417"	"47.9"	"8.53"	"525.33"	""	"1"	""	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;cytosol;mitochondrion"	"nucleic acid binding activity"	"Pf02536"	"51001"	"ENSG00000156469"	"MTERF3"	"B3KMG6; G3V130; hsa:51001; Q96E29; Q9Y301"	"Mitochondrial gene expression"	"PINK1-PRKN Mediated Mitophagy"	"2"	"0"	"24.4"	"13.3"	"13.4"	"28.0"	"17.6"	"26.7"	"55.0"	"50.6"	"53.3"	"58.1"	"83.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H444"	"Charged multivesicular body protein 4b OS=Homo sapiens OX=9606 GN=CHMP4B PE=1 SV=1"	"4"	"1"	"1"	"1"	"224"	"24.9"	"4.82"	"513.33"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf03357"	"128866"	"ENSG00000101421"	"CHMP4B"	"E1P5N4; hsa:128866; Q53ZD6; Q9H444"	""	"Sealing of the nuclear envelope (NE) by ESCRT-III; HCMV Late Events; Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT); Late endosomal microautophagy; Macroautophagy; Pyroptosis; Translation of Replicase and Assembly of the Replication Transcription Complex; Translation of Replicase and Assembly of the Replication Transcription Complex"	"9"	"0"	"275.6"	"123.4"	"179.8"	"167.0"	"151.1"	"196.6"	"345.8"	"294.4"	"241.6"	"363.4"	"585.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62072"	"Mitochondrial import inner membrane translocase subunit Tim10 OS=Homo sapiens OX=9606 GN=TIMM10 PE=1 SV=1"	"16"	"1"	"1"	"1"	"90"	"10.3"	"6.29"	"485.44"	""	"1"	""	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf02953"	"26519"	"ENSG00000134809"	"TIMM10"	"A8K136; hsa:26519; P62072; Q9WV99; Q9WVA0; Q9Y5J8"	""	"Mitochondrial protein import"	"1"	"0"	"12.0"	"8.7"	"19.2"	"12.4"	"16.8"	"15.6"	"24.3"	"19.6"	"11.2"	"24.0"	"34.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IZL8"	"Proline-, glutamic acid- and leucine-rich protein 1 OS=Homo sapiens OX=9606 GN=PELP1 PE=1 SV=2"	"1"	"1"	"1"	"1"	"1130"	"119.6"	"4.34"	"453.95"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf08166, Pf08167"	"27043"	"ENSG00000141456"	"PELP1"	"hsa:27043; O15450; Q5EGN3; Q6NTE6; Q8IZL8; Q96FT1; Q9BU60"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; PTK6 Expression"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P021"	"Cysteine-rich PDZ-binding protein OS=Homo sapiens OX=9606 GN=CRIPT PE=1 SV=1"	"12"	"1"	"1"	"1"	"101"	"11.2"	"9.47"	"439.69"	""	"1"	""	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf10235"	"9419"	"ENSG00000119878"	"CRIPT"	"hsa:9419; Q9P021"	""	""	"0"	"0"	"5.6"	"2.4"	"0.0"	"2.2"	"0.0"	"2.5"	"37.5"	"32.1"	"19.4"	"39.6"	"47.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63000"	"Ras-related C3 botulinum toxin substrate 1 OS=Homo sapiens OX=9606 GN=RAC1 PE=1 SV=1"	"8"	"1"	"1"	"1"	"192"	"21.4"	"8.50"	"426.91"	""	"1"	""	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00071"	"5879"	"ENSG00000136238"	"RAC1"	"hsa:5879; O95501; P15154; P63000; Q3Y4D3; Q5JAA8; Q9BTB4"	"Androgen receptor signaling pathway; Nucleotide-binding oligomerization domain (NOD) pathway; Target of rapamycin signaling; Physiological and pathological hypertrophy of the heart; MicroRNAs in cardiomyocyte hypertrophy; Integrin-mediated cell adhesion; RANKL/RANK signaling pathway; Leptin signaling pathway; TNF-related weak inducer of apoptosis (TWEAK) signaling pathway; Prolactin signaling pathway; Microtubule cytoskeleton regulation; RalA downstream regulated genes; B cell receptor signaling pathway; TNF-alpha signaling pathway; AGE/RAGE pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Spinal cord injury; Alpha 6 beta 4 signaling pathway; Amyotrophic lateral sclerosis (ALS); Cardiac hypertrophic response; Focal adhesion; RAC1/PAK1/p38/MMP2 pathway; Wnt signaling pathway; IL6 signaling pathway; Hepatitis C and hepatocellular carcinoma; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Microglia pathogen phagocytosis pathway; Robo4 and VEGF signaling pathways crosstalk; p38 MAPK signaling pathway; PI3K-Akt signaling pathway; Chromosomal and microsatellite instability in colorectal cancer ; Ebola virus infection in host; Ras signaling; Pancreatic adenocarcinoma pathway; Wnt signaling; Ciliary landscape; EGF/EGFR signaling pathway; Nonalcoholic fatty liver disease; Hippo signaling regulation pathways; Leukocyte-intrinsic Hippo pathway functions; Neural crest cell migration during development; Neural crest cell migration in cancer; Gastrin signaling pathway; Melanoma; Netrin-UNC5B signaling pathway; Insulin signaling; CAMKK2 pathway; Opioid receptor pathways; Regulation of actin cytoskeleton; GDNF signaling; 2q13 copy number variation syndrome; 2q21.1 copy number variation syndrome; 2q37 copy number variation syndrome; G13 signaling pathway; Genetic causes of porto-sinusoidal vascular disease; TROP2 regulatory signaling; 13q12.12 copy number variation; Interferon type I signaling pathways; DNA damage response (only ATM dependent); Toll-like receptor signaling pathway"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; EPHB-mediated forward signaling; Neutrophil degranulation; FCERI mediated MAPK activation; Signaling by SCF-KIT; DAP12 signaling; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases; PIP3 activates AKT signaling; Constitutive Signaling by Aberrant PI3K in Cancer; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; EPH-ephrin mediated repulsion of cells; MAPK6/MAPK4 signaling; RAC1 GTPase cycle; NRAGE signals death through JNK; Translocation of SLC2A4 (GLUT4) to the plasma membrane; RHO GTPases activate IQGAPs; RHO GTPases Activate Formins; DCC mediated attractive signaling; GPVI-mediated activation cascade; Ephrin signaling; Factors involved in megakaryocyte development and platelet production; RHO GTPases activate CIT; PCP/CE pathway; WNT5:FZD7-mediated leishmania damping; Sema3A PAK dependent Axon repulsion; SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion; Signal transduction by L1; RHO GTPases activate PKNs; RHO GTPases activate PAKs; DSCAM interactions; Azathioprine ADME; VEGFR2 mediated vascular permeability; Sema4D mediated inhibition of cell attachment and migration; Inactivation of CDC42 and RAC1; Activation of RAC1; CD28 dependent Vav1 pathway; Nef and signal transduction; RHO GTPases Activate NADPH Oxidases; NTRK2 activates RAC1; MET activates RAP1 and RAC1; Activation of RAC1 downstream of NMDARs; Activated NTRK2 signals through CDK5; RHO GTPases activate KTN1"	"108"	"0"	"12.2"	"11.3"	"11.9"	"17.0"	"17.8"	"15.4"	"30.2"	"37.4"	"22.4"	"44.6"	"55.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14192"	"Four and a half LIM domains protein 2 OS=Homo sapiens OX=9606 GN=FHL2 PE=1 SV=3"	"4"	"1"	"1"	"1"	"279"	"32.2"	"7.55"	"419.50"	""	"1"	""	"developmental processes;other biological processes"	"cytoskeleton;nucleus"	"other molecular function"	"Pf00412"	"2274"	"ENSG00000115641"	"FHL2"	"hsa:2274; Q13229; Q13644; Q14192; Q2I5I4; Q5TM15; Q9P294"	"Androgen receptor signaling pathway; RANKL/RANK signaling pathway; Ectoderm differentiation; VEGFA-VEGFR2 signaling"	"PPARA activates gene expression"	"5"	"0"	"73.4"	"60.4"	"75.6"	"61.9"	"74.4"	"68.4"	"85.5"	"86.6"	"85.5"	"100.3"	"159.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q4VC05"	"B-cell CLL/lymphoma 7 protein family member A OS=Homo sapiens OX=9606 GN=BCL7A PE=1 SV=1"	"5"	"1"	"1"	"1"	"210"	"22.8"	"5.14"	"416.63"	""	"1"	""	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	""	"Pf04714"	"605"	"ENSG00000110987; ENSG00000282873"	"BCL7A"	"B4DJN6; B7ZB21; hsa:605; Q13843; Q14CT7; Q4VC05"	""	""	"0"	"0"	"31.5"	"14.5"	"13.5"	"19.8"	"24.6"	"31.0"	"42.9"	"46.3"	"27.8"	"44.2"	"56.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UEE9"	"Craniofacial development protein 1 OS=Homo sapiens OX=9606 GN=CFDP1 PE=1 SV=1"	"4"	"1"	"1"	"1"	"299"	"33.6"	"4.81"	"415.40"	""	"1"	""	"cell adhesion;cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	""	"Pf07572"	"10428"	"ENSG00000153774"	"CFDP1"	"hsa:10428; O00393; O00404; Q9UEE9; Q9UEF0; Q9UEF1; Q9UEF8"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRF9"	"DNA polymerase epsilon subunit 3 OS=Homo sapiens OX=9606 GN=POLE3 PE=1 SV=1"	"6"	"1"	"1"	"1"	"147"	"16.8"	"4.74"	"384.19"	""	"1"	""	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00808"	"54107"	"ENSG00000148229"	"POLE3"	"hsa:54107; Q5W0U1; Q8N758; Q8NCE5; Q9NR32; Q9NRF9"	"Pyrimidine metabolism; Base excision repair; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"Activation of the pre-replicative complex; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Recognition of DNA damage by PCNA-containing replication complex; Dual Incision in GG-NER; Gap-filling DNA repair synthesis and ligation in GG-NER; PCNA-Dependent Long Patch Base Excision Repair; DNA replication initiation"	"16"	"0"	"77.8"	"23.4"	"56.8"	"54.0"	"50.1"	"59.5"	"117.8"	"85.9"	"48.7"	"98.3"	"164.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WUR7"	"UPF0235 protein C15orf40 OS=Homo sapiens OX=9606 GN=C15orf40 PE=1 SV=2"	"5"	"1"	"1"	"1"	"153"	"16.3"	"9.83"	"382.91"	""	"1"	""	""	"other cell component"	""	"Pf02594"	"123207"	"ENSG00000169609"	"C15orf40"	"A6NIC9; B2R5E7; F5GX92; F8WD31; G5EA00; hsa:123207; Q8WUR7"	"15q25 copy number variation"	""	"1"	"0"	"7.7"	"4.7"	"4.6"	"4.9"	"3.7"	"5.6"	"35.1"	"33.3"	"23.0"	"33.4"	"68.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IWZ6"	"Bardet-Biedl syndrome 7 protein OS=Homo sapiens OX=9606 GN=BBS7 PE=1 SV=2"	"1"	"1"	"1"	"1"	"715"	"80.3"	"6.05"	"380.79"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	""	"55212"	"ENSG00000138686"	"BBS7"	"hsa:55212; Q4W5P8; Q8IWZ6; Q8N581; Q9NVI4"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies; Bardet-Biedl syndrome"	"BBSome-mediated cargo-targeting to cilium"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H875"	"PRKR-interacting protein 1 OS=Homo sapiens OX=9606 GN=PRKRIP1 PE=1 SV=1"	"5"	"1"	"1"	"1"	"184"	"21.0"	"9.79"	"375.92"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf06658"	"79706"	"ENSG00000128563"	"PRKRIP1"	"B4DGM2; hsa:79706; Q8NDM6; Q96CF8; Q9H875"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"100.9"	"47.0"	"81.7"	"66.8"	"75.9"	"76.3"	"133.7"	"112.4"	"77.7"	"108.0"	"197.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92576"	"PHD finger protein 3 OS=Homo sapiens OX=9606 GN=PHF3 PE=1 SV=3"	"0"	"1"	"1"	"1"	"2039"	"229.3"	"6.96"	"369.52"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00628, Pf07500, Pf07744"	"23469"	"ENSG00000118482"	"PHF3"	"A3KFI8; hsa:23469; Q14CR5; Q5CZI1; Q5T1T6; Q92576; Q9NQ16; Q9UI45"	""	""	"0"	"0"	"42.5"	"26.5"	"43.0"	"37.5"	"47.6"	"48.7"	"91.1"	"81.3"	"57.7"	"91.5"	"127.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NX55"	"Huntingtin-interacting protein K OS=Homo sapiens OX=9606 GN=HYPK PE=1 SV=2"	"12"	"1"	"1"	"1"	"129"	"14.7"	"4.93"	"366.33"	""	"1"	""	"protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf04419, Pf19026"	"100137436; 101127706; 104002286; 104679625; 105491324; 105549422; 105588143; 108521295; 25764; 713266"	"ENSCATG00000038565; ENSGGOG00000014809; ENSMFAG00000057677; ENSMLEG00000000898; ENSMMUG00000022768; ENSMNEG00000018318; ENSPANG00000018102; ENSPPAG00000034659; ENSPTEG00000009792; ENSPTEG00000019135; ENSPTRG00000038721; ENSRBIG00000028237; ENSRROG00000039445; ENSTGEG00000007663"	"HYPK; LOC113219833"	"A0A024R5Q1; A0A1D5R5K3; A0A2I2YQJ1; A0A2J8NTT0; A0A2K5N035; A0A2K5TR12; A0A2K5XAQ0; A0A2K6AXP0; A0A2K6KBN5; A0A2K6QRU2; A0A2R9B6N1; A0A663DGD1; A0A6D2Y1W8; A0A8C9GZF6; A0A8D2ERJ4; A0A8J8XMG0; A9X1C4; F7GC11; G7MX15; G7PB77; H2Q9B3; hsa:25764; mcc:713266; mleu:105549422; mni:105491324; panu:100137436; ptr:104002286; rbb:108521295; rro:104679625"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H6R0"	"ATP-dependent RNA helicase DHX33 OS=Homo sapiens OX=9606 GN=DHX33 PE=1 SV=2"	"2"	"1"	"1"	"1"	"707"	"78.8"	"8.91"	"356.06"	""	"1"	""	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"56919"	"ENSG00000005100"	"DHX33"	"B4DHF9; hsa:56919; Q4G149; Q5CZ73; Q9H5M9; Q9H6R0"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N8S7"	"Protein enabled homolog OS=Homo sapiens OX=9606 GN=ENAH PE=1 SV=2"	"2"	"1"	"1"	"1"	"591"	"66.5"	"6.93"	"354.34"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00568, Pf08776"	"55740"	"ENSG00000154380"	"ENAH"	"D0PQI2; hsa:55740; Q502W5; Q5T5M7; Q5VTQ9; Q5VTR0; Q8N8S7; Q9NVF3; Q9UFB8"	"Regulation of actin cytoskeleton"	"Generation of second messenger molecules; Signaling by ROBO receptors"	"3"	"0"	"10.1"	"7.2"	"8.0"	"6.3"	"9.8"	"8.7"	"10.4"	"15.7"	"8.9"	"16.3"	"22.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6I4"	"Ubiquitin carboxyl-terminal hydrolase 3 OS=Homo sapiens OX=9606 GN=USP3 PE=1 SV=2"	"3"	"1"	"1"	"1"	"520"	"58.9"	"8.18"	"335.74"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf00443, Pf02148"	"9960"	"ENSG00000140455"	"USP3"	"B4DVU5; F5H1A6; hsa:9960; Q8WVD0; Q9Y6I4"	""	"Ub-specific processing proteases"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3B2"	"Exosome complex component CSL4 OS=Homo sapiens OX=9606 GN=EXOSC1 PE=1 SV=1"	"6"	"1"	"1"	"1"	"195"	"21.4"	"8.24"	"328.19"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity"	"Pf10447, Pf14382"	"51013"	"ENSG00000171311"	"EXOSC1"	"B2R9B3; hsa:51013; Q5JTH3; Q9Y3B2"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	"6"	"0"	"9.3"	"7.6"	"7.9"	"8.3"	"6.0"	"5.9"	"18.4"	"17.1"	"10.6"	"19.1"	"23.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRR8"	"G patch domain-containing protein 1 OS=Homo sapiens OX=9606 GN=GPATCH1 PE=1 SV=1"	"1"	"1"	"1"	"1"	"931"	"103.3"	"7.05"	"317.11"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf01585, Pf07713"	"55094"	"ENSG00000076650"	"GPATCH1"	"hsa:55094; Q8IZV6; Q8N3B7; Q9BRR8; Q9NW94"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"B7ZAP0"	"Rab GTPase-activating protein 1-like, isoform 10 OS=Homo sapiens OX=9606 GN=RABGAP1L PE=1 SV=1"	"4"	"1"	"1"	"1"	"253"	"29.0"	"5.33"	"314.92"	""	"1"	""	""	""	""	""	"9910"	"ENSG00000152061"	"RABGAP1L"	"B7ZAA4; B7ZAP0; hsa:9910"	""	""	"0"	"0"	"137.1"	"71.1"	"120.7"	"113.5"	"127.0"	"138.7"	"259.6"	"231.3"	"162.2"	"256.5"	"325.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q969T9"	"WW domain-binding protein 2 OS=Homo sapiens OX=9606 GN=WBP2 PE=1 SV=1"	"4"	"1"	"1"	"1"	"261"	"28.1"	"5.91"	"302.95"	""	"1"	""	"cell organization and biogenesis;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02893"	"23558"	"ENSG00000132471"	"WBP2"	"B4DFG2; hsa:23558; O95638; Q969T9"	""	""	"0"	"0"	"27.2"	"20.6"	"18.7"	"24.2"	"17.0"	"29.2"	"40.7"	"41.5"	"41.1"	"48.6"	"80.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00268"	"Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2"	"1"	"1"	"1"	"1"	"1085"	"110.0"	"9.94"	"300.74"	""	"1"	""	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf05236, Pf07531"	"6874"	"ENSG00000130699"	"TAF4"	"A6NGD9; hsa:6874; O00268; Q5TBP6; Q99721; Q9BR40; Q9BX42"	""	"RNA Polymerase II Pre-transcription Events; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; Regulation of TP53 Activity through Phosphorylation; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation"	"9"	"0"	"7.8"	"6.4"	"7.3"	"3.6"	"8.2"	"10.9"	"15.9"	"14.1"	"13.1"	"16.3"	"21.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14247"	"Src substrate cortactin OS=Homo sapiens OX=9606 GN=CTTN PE=1 SV=2"	"2"	"1"	"1"	"1"	"550"	"61.5"	"5.40"	"291.51"	""	"1"	""	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf02218, Pf14604"	"2017"	"ENSG00000085733; ENSG00000288401"	"CTTN"	"hsa:2017; Q14247; Q8N707; Q96H99"	"Pathogenic Escherichia coli infection; Hepatitis C and hepatocellular carcinoma"	"Clathrin-mediated endocytosis; RHO GTPases activate PAKs"	"4"	"0"	"294.0"	"143.9"	"219.3"	"224.3"	"189.8"	"267.3"	"465.1"	"407.5"	"346.8"	"510.4"	"735.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRG9"	"Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1"	"2"	"1"	"1"	"1"	"546"	"59.5"	"7.50"	"289.30"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus"	""	"Pf00400"	"8086"	"ENSG00000094914"	"AAAS"	"hsa:8086; Q5JB47; Q9NRG9; Q9NWI6; Q9UG19"	""	"HCMV Early Events; ISG15 antiviral mechanism; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Transport of Mature mRNA derived from an Intron-Containing Transcript; HCMV Late Events; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; RHOA GTPase cycle"	"29"	"0"	"33.8"	"26.0"	"30.9"	"22.5"	"31.3"	"34.6"	"49.5"	"34.8"	"28.5"	"52.6"	"77.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQ67"	"Glutamate-rich WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=GRWD1 PE=1 SV=1"	"2"	"1"	"1"	"1"	"446"	"49.4"	"4.92"	"287.26"	""	"1"	""	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400, Pf12265"	"83743"	"ENSG00000105447"	"GRWD1"	"A0MNN5; hsa:83743; Q8TF59; Q9BQ67"	""	""	"0"	"0"	"109.4"	"80.2"	"109.4"	"92.7"	"100.5"	"124.4"	"275.2"	"267.4"	"172.2"	"291.6"	"375.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86UE8"	"Serine/threonine-protein kinase tousled-like 2 OS=Homo sapiens OX=9606 GN=TLK2 PE=1 SV=2"	"2"	"1"	"1"	"1"	"772"	"87.6"	"8.41"	"287.26"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"11011"	"ENSG00000146872"	"TLK2"	"D3DU07; hsa:11011; Q86UE8; Q9UKI7; Q9Y4F7"	"miRNA regulation of DNA damage response; DNA damage response"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13627"	"Dual specificity tyrosine-phosphorylation-regulated kinase 1A OS=Homo sapiens OX=9606 GN=DYRK1A PE=1 SV=2"	"1"	"1"	"1"	"1"	"763"	"85.5"	"8.75"	"285.95"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00069"	"1859"	"ENSG00000157540"	"DYRK1A"	"hsa:1859; O60769; Q13627; Q92582; Q92810; Q9UNM5"	"T cell receptor and co-stimulatory signaling; DYRK1A involvement regarding cell proliferation in brain development"	"G0 and Early G1"	"3"	"0"	"54.3"	"24.1"	"45.3"	"46.6"	"42.8"	"54.0"	"173.4"	"168.0"	"129.2"	"168.5"	"234.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNF1"	"Melanoma-associated antigen D2 OS=Homo sapiens OX=9606 GN=MAGED2 PE=1 SV=2"	"1"	"1"	"1"	"1"	"606"	"64.9"	"9.32"	"285.13"	""	"1"	""	"transport;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf01454"	"10916"	"ENSG00000102316"	"MAGED2"	"A6NMX0; hsa:10916; O76058; Q5BJF3; Q8NAL6; Q9H218; Q9P0U9; Q9UM52; Q9UNF1"	""	"Platelet degranulation"	"1"	"0"	"33.7"	"24.9"	"27.5"	"31.2"	"36.0"	"38.4"	"59.9"	"54.3"	"40.4"	"66.3"	"99.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBF8"	"Phosphatidylinositol 4-kinase beta OS=Homo sapiens OX=9606 GN=PI4KB PE=1 SV=1"	"1"	"1"	"1"	"1"	"816"	"91.3"	"6.25"	"284.51"	""	"1"	""	"cell organization and biogenesis;other metabolic processes;transport;signal transduction"	"other membranes;cytosol;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00454"	"5298"	"ENSG00000143393"	"PI4KB"	"B4DGI2; hsa:5298; O15096; P78405; Q5VWB9; Q5VWC0; Q5VWC1; Q9BWR6; Q9UBF8"	""	"Synthesis of PIPs at the Golgi membrane"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13480"	"GRB2-associated-binding protein 1 OS=Homo sapiens OX=9606 GN=GAB1 PE=1 SV=2"	"2"	"1"	"1"	"1"	"694"	"76.6"	"5.96"	"282.65"	""	"1"	""	"developmental processes;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00169"	"2549"	"ENSG00000109458"	"GAB1"	"A8K152; hsa:2549; Q13480; Q4W5G2; Q6P1W2"	"Glioblastoma signaling pathways; Androgen receptor network in prostate cancer; B cell receptor signaling pathway; Alpha 6 beta 4 signaling pathway; Hepatocyte growth factor receptor signaling; IL6 signaling pathway; BDNF-TrkB signaling; VEGFA-VEGFR2 signaling; Embryonic stem cell pluripotency pathways; Ras signaling; EGF/EGFR signaling pathway; Fragile X syndrome; Head and neck squamous cell carcinoma; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; GDNF signaling; A network map of Macrophage-stimulating protein (MSP) signaling; 4p16.3 copy number variation; 5q35 copy number variation; ErbB signaling pathway"	"Signaling by ERBB2 KD Mutants; Signaling by FGFR1 in disease; Signaling by FGFR2 in disease; Signaling by FGFR3 in disease; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; Constitutive Signaling by EGFRvIII; Signaling by ERBB2 ECD mutants; Signaling by FGFR4 in disease; PIP3 activates AKT signaling; Constitutive Signaling by Aberrant PI3K in Cancer; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; RET signaling; Erythropoietin activates Phosphoinositide-3-kinase (PI3K); PI3K Cascade; PI3K events in ERBB2 signaling; GAB1 signalosome; PI-3K cascade:FGFR1; PI-3K cascade:FGFR2; PI-3K cascade:FGFR3; PI-3K cascade:FGFR4; MET activates PI3K/AKT signaling; MET activates PTPN11; MET activates RAP1 and RAC1; MET receptor recycling; Activated NTRK2 signals through PI3K"	"45"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y388"	"RNA-binding motif protein, X-linked 2 OS=Homo sapiens OX=9606 GN=RBMX2 PE=1 SV=2"	"5"	"1"	"1"	"1"	"322"	"37.3"	"9.83"	"278.38"	""	"1"	""	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"other membranes;ER/Golgi;nucleus"	""	"Pf00076"	"51634"	"ENSG00000134597"	"RBMX2"	"A8K9Z0; hsa:51634; Q5JY82; Q9Y388; Q9Y3I8"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15460"	"Prolyl 4-hydroxylase subunit alpha-2 OS=Homo sapiens OX=9606 GN=P4HA2 PE=1 SV=1"	"2"	"1"	"1"	"1"	"535"	"60.9"	"5.71"	"277.56"	""	"1"	""	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf08336, Pf13640"	"8974"	"ENSG00000072682"	"P4HA2"	"D3DQ85; D3DQ86; hsa:8974; O15460; Q8WWN0"	"VEGFA-VEGFR2 signaling; Amino acid metabolism; Type I collagen synthesis in the context of osteogenesis imperfecta"	"Collagen biosynthesis and modifying enzymes"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3A3"	"MOB-like protein phocein OS=Homo sapiens OX=9606 GN=MOB4 PE=1 SV=1"	"4"	"1"	"1"	"1"	"225"	"26.0"	"5.78"	"273.58"	""	"1"	""	""	"other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf03637"	"25843"	"ENSG00000115540"	"MOB4"	"B4DML0; hsa:25843; Q53SE0; Q7Z4Y6; Q9H2P3; Q9H5J1; Q9Y3A3; Q9Y4T8"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P2K5"	"Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3"	"2"	"1"	"1"	"1"	"600"	"64.1"	"8.75"	"267.28"	""	"1"	""	"developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"50804"	"ENSG00000104177"	"MYEF2"	"A7MCZ9; C9J921; C9K0J4; hsa:50804; Q6NUM5; Q7L388; Q7Z4B7; Q9H922; Q9NUQ1; Q9P2K5"	"Physiological and pathological hypertrophy of the heart; MicroRNAs in cardiomyocyte hypertrophy; Transcription factors regulate miRNAs related to cardiac hypertrophy; Mitochondrial gene expression"	""	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P32780"	"General transcription factor IIH subunit 1 OS=Homo sapiens OX=9606 GN=GTF2H1 PE=1 SV=1"	"1"	"1"	"1"	"1"	"548"	"62.0"	"8.66"	"264.90"	""	"1"	""	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus"	"other molecular function"	"Pf03909, Pf08567"	"2965"	"ENSG00000110768; ENSG00000288114"	"GTF2H1"	"B3KXE0; D3DQY2; hsa:2965; P32780; Q6I9Y7; Q9H5K5; Q9NQD9"	"Eukaryotic transcription initiation; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Dual Incision in GG-NER"	"33"	"0"	"32.6"	"11.3"	"34.8"	"30.1"	"36.0"	"38.7"	"159.0"	"224.5"	"290.3"	"597.5"	"904.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P39656"	"Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4"	"2"	"1"	"1"	"1"	"456"	"50.8"	"6.55"	"264.70"	""	"1"	""	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity"	"Pf03345"	"1650"	"ENSG00000244038"	"DDOST"	"B2RDQ4; B4DJE3; B4DLI2; hsa:1650; O43244; P39656; Q5VWA5; Q8NI93; Q9BUI2"	"AGE/RAGE pathway; N-glycan biosynthesis"	"Neutrophil degranulation; SRP-dependent cotranslational protein targeting to membrane; Advanced glycosylation endproduct receptor signaling; Asparagine N-linked glycosylation; Maturation of spike protein"	"7"	"0"	"22.1"	"14.3"	"15.8"	"8.6"	"17.0"	"15.6"	"27.2"	"22.2"	"14.5"	"27.6"	"45.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NX07"	"tRNA selenocysteine 1-associated protein 1 OS=Homo sapiens OX=9606 GN=TRNAU1AP PE=1 SV=1"	"2"	"1"	"1"	"1"	"287"	"32.5"	"4.74"	"259.98"	""	"1"	""	"protein metabolism;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf17654"	"54952"	"ENSG00000180098"	"TRNAU1AP"	"hsa:54952; Q86SU7; Q9NX07"	""	""	"0"	"0"	"17.6"	"10.6"	"16.1"	"16.2"	"19.5"	"18.5"	"32.6"	"29.6"	"23.0"	"28.0"	"37.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2E4"	"Disco-interacting protein 2 homolog C OS=Homo sapiens OX=9606 GN=DIP2C PE=1 SV=2"	"1"	"1"	"1"	"1"	"1556"	"170.7"	"7.39"	"259.92"	""	"1"	""	""	""	""	"Pf00501, Pf06464"	"22982"	"ENSG00000151240"	"DIP2C"	"B4DPI5; hsa:22982; Q5SS78; Q9Y2E4"	""	""	"0"	"0"	"8.2"	"4.9"	"9.5"	"10.3"	"10.2"	"11.0"	"24.5"	"23.0"	"21.4"	"34.8"	"50.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q3B7T1"	"Erythroid differentiation-related factor 1 OS=Homo sapiens OX=9606 GN=EDRF1 PE=1 SV=1"	"0"	"1"	"1"	"1"	"1238"	"138.4"	"6.33"	"259.11"	""	"1"	""	"other biological processes"	"nucleus"	""	""	"26098"	"ENSG00000107938"	"EDRF1"	"B2RC65; hsa:26098; Q3B7T1; Q3KR40; Q4G190; Q5VZQ4; Q8IZ74; Q9Y3W4"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y315"	"Deoxyribose-phosphate aldolase OS=Homo sapiens OX=9606 GN=DERA PE=1 SV=2"	"3"	"1"	"1"	"1"	"318"	"35.2"	"8.94"	"258.65"	""	"1"	""	"other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf01791"	"51071"	"ENSG00000023697"	"DERA"	"hsa:51071; Q53HN9; Q6PHW2; Q9Y315"	"Pentose phosphate pathway in senescent cells"	"Neutrophil degranulation; Pentose phosphate pathway"	"3"	"0"	"10.1"	"5.8"	"21.5"	"7.3"	"11.1"	"12.2"	"16.0"	"15.3"	"7.6"	"16.8"	"27.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P56180"	"Putative tyrosine-protein phosphatase TPTE OS=Homo sapiens OX=9606 GN=TPTE PE=1 SV=3"	"1"	"1"	"1"	"1"	"551"	"64.3"	"8.68"	"258.00"	""	"1"	""	"protein metabolism;other metabolic processes;signal transduction"	"other membranes;cytosol"	"other molecular function"	"Pf10409"	"7179"	"ENSG00000274391"	"TPTE"	"B2RAP7; C9J6D6; C9JKK8; hsa:7179; P56180; Q6XPS4; Q6XPS5; Q71JA8; Q8NCS8"	""	"Synthesis of PIPs at the Golgi membrane"	"1"	"0"	"89.4"	"55.6"	"78.2"	"79.0"	"83.0"	"77.3"	"159.3"	"154.0"	"114.0"	"157.1"	"185.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N4H5"	"Mitochondrial import receptor subunit TOM5 homolog OS=Homo sapiens OX=9606 GN=TOMM5 PE=1 SV=1"	"14"	"1"	"1"	"1"	"51"	"6.0"	"9.70"	"257.48"	""	"1"	""	"cell organization and biogenesis;transport"	"other membranes;mitochondrion"	""	"Pf10642"	"401505"	"ENSG00000175768"	"TOMM5"	"B2DG07; F6S928; hsa:401505; Q5JRT7; Q8N4H5"	""	"Mitochondrial protein import; PINK1-PRKN Mediated Mitophagy"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13217"	"DnaJ homolog subfamily C member 3 OS=Homo sapiens OX=9606 GN=DNAJC3 PE=1 SV=1"	"1"	"1"	"1"	"1"	"504"	"57.5"	"6.15"	"257.23"	""	"1"	""	"protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00226, Pf00515, Pf13181, Pf13432"	"5611"	"ENSG00000102580"	"DNAJC3"	"hsa:5611; Q13217; Q86WT9; Q8N4N2"	"Photodynamic therapy-induced unfolded protein response"	"Neutrophil degranulation; Viral mRNA Translation; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; XBP1(S) activates chaperone genes"	"6"	"0"	"10.3"	"2.5"	"3.5"	"8.2"	"5.4"	"10.8"	"36.7"	"47.9"	"34.7"	"43.1"	"74.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q969F1"	"General transcription factor 3C polypeptide 6 OS=Homo sapiens OX=9606 GN=GTF3C6 PE=1 SV=1"	"8"	"1"	"1"	"1"	"213"	"24.0"	"4.21"	"256.82"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf10419"	"112495"	"ENSG00000155115"	"GTF3C6"	"hsa:112495; Q5VXN2; Q969F1"	""	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQP7"	"Mitochondrial genome maintenance exonuclease 1 OS=Homo sapiens OX=9606 GN=MGME1 PE=1 SV=1"	"3"	"1"	"1"	"1"	"344"	"39.4"	"7.68"	"255.59"	""	"1"	""	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response"	"mitochondrion"	"other molecular function"	"Pf12705"	"92667"	"ENSG00000125871"	"MGME1"	"B2RDG5; D3DW29; hsa:92667; Q96SW3; Q9BQP7"	"Primary ovarian insufficiency"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NVT9"	"Armadillo repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=ARMC1 PE=1 SV=1"	"2"	"1"	"1"	"1"	"282"	"31.3"	"5.74"	"255.19"	""	"1"	""	"cell organization and biogenesis"	"other membranes;cytosol;mitochondrion"	"other molecular function"	"Pf00514"	"55156"	"ENSG00000104442"	"ARMC1"	"B4E2W7; hsa:55156; Q9H018; Q9H820; Q9NVT9"	""	""	"0"	"0"	"76.5"	"32.7"	"46.9"	"65.5"	"63.5"	"89.9"	"130.8"	"122.9"	"102.9"	"130.1"	"164.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61764"	"Syntaxin-binding protein 1 OS=Homo sapiens OX=9606 GN=STXBP1 PE=1 SV=1"	"1"	"1"	"1"	"1"	"594"	"67.5"	"6.96"	"255.18"	""	"1"	""	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00995"	"6812"	"ENSG00000136854"	"STXBP1"	"B1AM97; hsa:6812; P61764; Q28208; Q62759; Q64320; Q68CM6; Q96TG8"	"Synaptic vesicle pathway; Rett syndrome causing genes; EGF/EGFR signaling pathway; Insulin signaling; 15q11q13 copy number variation"	"Regulation of insulin secretion; Neurexins and neuroligins"	"7"	"0"	"46.1"	"20.6"	"31.0"	"31.7"	"29.0"	"34.3"	"64.8"	"63.0"	"52.5"	"73.5"	"132.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14929"	"Histone acetyltransferase type B catalytic subunit OS=Homo sapiens OX=9606 GN=HAT1 PE=1 SV=1"	"1"	"1"	"1"	"1"	"419"	"49.5"	"5.69"	"254.99"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf10394"	"100598934; 100970485; 102127119; 103217315; 104673520; 105548069; 105579802; 695933"	"ENSCATG00000044185; ENSCSAG00000014790; ENSMFAG00000044656; ENSMLEG00000030988; ENSMMUG00000007313; ENSNLEG00000031960; ENSPPAG00000043422; ENSPPYG00000012932; ENSPTEG00000037699; ENSPTRG00000012637; ENSRROG00000043073; ENSTGEG00000018560"	"HAT1"	"A0A0D9RQL6; A0A2I3GP06; A0A2J8PQW8; A0A2J8VQX1; A0A2K5P0H4; A0A2K5VNP4; A0A2K5YDV9; A0A2K6REU7; A0A2R9CI71; A0A663DCK2; A0A6D2WXR9; A0A8C9IWX6; A0A8D2FM88; A0A8J8XV08; A0A8J8YED4; caty:105579802; csab:103217315; F7GNR2; F7GNT9; G7N8B0; G7PKT8; H2P7T9; H2QIZ3; mcc:695933; mcf:102127119; mleu:105548069; nle:100598934; pps:100970485; rro:104673520"	""	""	"0"	"0"	"169.9"	"66.4"	"125.0"	"106.9"	"107.8"	"132.3"	"220.8"	"195.3"	"148.0"	"216.4"	"305.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H6Y2"	"WD repeat-containing protein 55 OS=Homo sapiens OX=9606 GN=WDR55 PE=1 SV=2"	"2"	"1"	"1"	"1"	"383"	"42.0"	"4.92"	"254.73"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf00400, Pf12894"	"54853"	"ENSG00000120314"	"WDR55"	"hsa:54853; Q9H6Y2; Q9NXK4"	""	""	"0"	"0"	"20.0"	"8.6"	"15.4"	"19.6"	"13.8"	"19.2"	"45.0"	"34.6"	"24.7"	"36.1"	"45.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75334"	"Liprin-alpha-2 OS=Homo sapiens OX=9606 GN=PPFIA2 PE=1 SV=2"	"1"	"1"	"1"	"1"	"1257"	"143.2"	"6.11"	"252.59"	""	"1"	""	"cell adhesion;cell organization and biogenesis;transport;other biological processes"	"cytosol;other cell component"	""	"Pf00536, Pf07647"	"8499"	"ENSG00000139220"	"PPFIA2"	"B3KVT5; B3KXA0; B7Z2A6; B7Z3U9; B7Z663; B7ZKZ5; E7ERB8; E7ETG6; F8VP68; hsa:8499; O75334; Q2M3G8"	""	"Glutamate Neurotransmitter Release Cycle; Serotonin Neurotransmitter Release Cycle; Norepinephrine Neurotransmitter Release Cycle; Dopamine Neurotransmitter Release Cycle; Acetylcholine Neurotransmitter Release Cycle; Receptor-type tyrosine-protein phosphatases"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NGY6"	"Olfactory receptor 6N2 OS=Homo sapiens OX=9606 GN=OR6N2 PE=3 SV=1"	"2"	"1"	"1"	"1"	"317"	"35.7"	"8.82"	"251.54"	""	"1"	""	"signal transduction;other biological processes"	"plasma membrane;other membranes"	"other molecular function"	"Pf13853"	"81442"	"ENSG00000188340"	"OR6N2"	"hsa:81442; Q6IFR2; Q8NGY6"	""	"Expression and translocation of olfactory receptors"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60343"	"TBC1 domain family member 4 OS=Homo sapiens OX=9606 GN=TBC1D4 PE=1 SV=2"	"0"	"1"	"1"	"1"	"1298"	"146.5"	"7.01"	"251.48"	""	"1"	""	"transport;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity"	"Pf00566, Pf00640, Pf11830"	"9882"	"ENSG00000136111"	"TBC1D4"	"A7E2X8; B4DU25; B4E235; B6ETN8; B6ETN9; hsa:9882; O60343; Q5W0B9; Q68D14"	"Ciliary landscape; Thyroid hormones production and peripheral downstream signaling effects; Insulin signaling"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"	"4"	"0"	"41.7"	"16.3"	"17.9"	"29.0"	"27.5"	"40.1"	"62.4"	"54.0"	"34.3"	"74.0"	"90.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15024"	"Exosome complex component RRP42 OS=Homo sapiens OX=9606 GN=EXOSC7 PE=1 SV=3"	"2"	"1"	"1"	"1"	"291"	"31.8"	"5.19"	"251.23"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01138, Pf03725"	"23016"	"ENSG00000075914"	"EXOSC7"	"hsa:23016; Q15024; Q96E72"	"Ciliary landscape"	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	"7"	"0"	"33.7"	"17.9"	"31.2"	"28.7"	"33.7"	"27.0"	"62.7"	"60.9"	"31.6"	"53.0"	"110.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NBU5"	"ATPase family AAA domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ATAD1 PE=1 SV=1"	"2"	"1"	"1"	"1"	"361"	"40.7"	"6.90"	"250.86"	""	"1"	""	"other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00004, Pf17862"	"84896"	"ENSG00000138138; ENSG00000283024"	"ATAD1"	"D3DR26; hsa:84896; Q6DKG1; Q6P4B9; Q8N3G1; Q8NBU5; Q8WYR9; Q969Y3"	""	"Class I peroxisomal membrane protein import"	"1"	"0"	"56.4"	"42.1"	"60.5"	"43.9"	"45.0"	"55.1"	"92.5"	"82.0"	"64.8"	"97.1"	"143.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6X9"	"ATPase MORC2 OS=Homo sapiens OX=9606 GN=MORC2 PE=1 SV=2"	"1"	"1"	"1"	"1"	"1032"	"117.8"	"8.38"	"249.82"	""	"1"	""	"cell organization and biogenesis;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf07496, Pf13589, Pf17942"	"22880"	"ENSG00000133422"	"MORC2"	"B2RNB1; hsa:22880; Q9UF28; Q9Y6V2; Q9Y6X9"	""	"Fatty acyl-CoA biosynthesis"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N6H7"	"ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1"	"1"	"1"	"1"	"1"	"521"	"56.7"	"7.99"	"249.73"	""	"1"	""	"cell organization and biogenesis;transport"	"plasma membrane;other membranes;cytosol;ER/Golgi"	"enzyme regulator activity;other molecular function"	"Pf01412"	"84364"	"ENSG00000149182"	"ARFGAP2"	"B4DX29; B7Z9M7; D3DQQ9; hsa:84364; Q3LIF2; Q8N3I1; Q8N6H7; Q96SX7"	"IL-18 signaling pathway; 5q35 copy number variation"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport; CDC42 GTPase cycle"	"5"	"0"	"29.6"	"10.2"	"18.3"	"20.4"	"17.6"	"30.9"	"57.7"	"65.5"	"44.8"	"67.1"	"108.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WZ42"	"Titin OS=Homo sapiens OX=9606 GN=TTN PE=1 SV=4"	"0"	"1"	"1"	"1"	"34350"	"3813.7"	"6.35"	"249.59"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00041, Pf00069, Pf02818, Pf07679, Pf09042, Pf18362"	"7273"	"ENSG00000155657"	"TTN"	"A6NKB1; E7EQE6; E7ET18; hsa:7273; K7ENY1; Q10465; Q10466; Q15598; Q2XUS3; Q32Q60; Q4U1Z6; Q4ZG20; Q6NSG0; Q6PDB1; Q6PJP0; Q7KYM2; Q7KYN4; Q7KYN5; Q7LDM3; Q7Z2X3; Q8TCG8; Q8WZ42; Q8WZ51; Q8WZ52; Q8WZ53; Q8WZB3; Q92761; Q92762; Q9UD97; Q9UP84; Q9Y6L9"	"Striated muscle contraction pathway; Cardiomyocyte signaling pathways converging on Titin"	"Platelet degranulation ; Striated Muscle Contraction"	"4"	"0"	"34.6"	"18.1"	"27.4"	"26.6"	"19.4"	"34.0"	"60.6"	"50.9"	"35.6"	"48.1"	"59.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14690"	"Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3"	"1"	"1"	"1"	"1"	"1871"	"208.6"	"8.87"	"249.34"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00575, Pf05843"	"22984"	"ENSG00000148843"	"PDCD11"	"hsa:22984; Q14690; Q2TA92; Q5W093; Q6P2J3; Q86VQ8; Q9H4P1"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86YB8"	"ERO1-like protein beta OS=Homo sapiens OX=9606 GN=ERO1B PE=1 SV=2"	"2"	"1"	"1"	"1"	"467"	"53.5"	"7.99"	"249.32"	""	"1"	""	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf04137"	"56605"	"ENSG00000086619"	"ERO1B"	"B4DF57; hsa:56605; Q5T1H4; Q86YB8; Q8IZ11; Q9NR62"	""	"Insulin processing"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42566"	"Epidermal growth factor receptor substrate 15 OS=Homo sapiens OX=9606 GN=EPS15 PE=1 SV=2"	"1"	"1"	"1"	"1"	"896"	"98.6"	"4.64"	"249.10"	""	"1"	""	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	""	"2060"	"ENSG00000085832"	"EPS15"	"B2R8J7; D3DPJ2; hsa:2060; P42566; Q5SRH4"	"VEGFA-VEGFR2 signaling; Ebola virus infection in host; EGF/EGFR signaling pathway"	"Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation; Negative regulation of MET activity; InlB-mediated entry of Listeria monocytogenes into host cell"	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBI6"	"Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 OS=Homo sapiens OX=9606 GN=GNG12 PE=1 SV=3"	"10"	"1"	"1"	"1"	"72"	"8.0"	"8.97"	"247.82"	""	"1"	""	"signal transduction"	"plasma membrane;other membranes"	"other molecular function"	"Pf00631"	"55970"	"ENSG00000172380"	"GNG12"	"hsa:55970; Q69YP5; Q9BRV5; Q9UBI6"	"Myometrial relaxation and contraction pathways; G protein signaling pathways; MAPK signaling pathway; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Ras signaling; Regulation of actin cytoskeleton; Calcium regulation in cardiac cells"	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Ca2+ pathway; G alpha (12/13) signalling events; G alpha (q) signalling events; G alpha (i) signalling events; G alpha (z) signalling events; ADP signalling through P2Y purinoceptor 12; Extra-nuclear estrogen signaling; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; Thrombin signalling through proteinase activated receptors (PARs); Activation of G protein gated Potassium channels; G-protein activation; G beta:gamma signalling through PI3Kgamma; Prostacyclin signalling through prostacyclin receptor; Adrenaline,noradrenaline inhibits insulin secretion; G beta:gamma signalling through PLC beta; ADP signalling through P2Y purinoceptor 1; Glucagon-type ligand receptors; Thromboxane signalling through TP receptor; Vasopressin regulates renal water homeostasis via Aquaporins; Presynaptic function of Kainate receptors; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; G beta:gamma signalling through BTK; G beta:gamma signalling through CDC42; Inhibition  of voltage gated Ca2+ channels via Gbeta/gamma subunits; Glucagon signaling in metabolic regulation"	"37"	"0"	"259.0"	"169.8"	"197.7"	"145.3"	"187.5"	"186.5"	"266.6"	"250.0"	"229.8"	"319.6"	"370.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00410"	"Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4"	"1"	"1"	"1"	"1"	"1097"	"123.6"	"4.94"	"247.00"	""	"1"	""	"transport;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02985, Pf18808, Pf18816, Pf18829"	"3843"	"ENSG00000065150"	"IPO5"	"B4DZA0; hsa:3843; O00410; O15257; Q5T578; Q86XC7"	""	"vRNP Assembly"	"1"	"0"	"16.4"	"12.5"	"20.4"	"14.3"	"17.0"	"22.5"	"25.9"	"24.4"	"14.4"	"31.4"	"43.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q08945"	"FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1"	"2"	"1"	"1"	"1"	"709"	"81.0"	"6.87"	"246.99"	""	"1"	""	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00505, Pf03531, Pf08512, Pf17292"	"6749"	"ENSG00000149136"	"SSRP1"	"hsa:6749; Q08945; Q5BJG8"	""	"Regulation of TP53 Activity through Phosphorylation; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes"	"12"	"0"	"25.1"	"16.9"	"24.2"	"25.0"	"26.7"	"30.6"	"61.7"	"73.5"	"81.5"	"118.5"	"131.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H9L3"	"Interferon-stimulated 20 kDa exonuclease-like 2 OS=Homo sapiens OX=9606 GN=ISG20L2 PE=1 SV=1"	"2"	"1"	"1"	"1"	"353"	"39.1"	"9.94"	"245.11"	""	"1"	""	"other biological processes"	"nucleus"	"other molecular function"	"Pf00929"	"81875"	"ENSG00000143319"	"ISG20L2"	"D3DVC6; hsa:81875; Q64KA2; Q9H9L3"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"5.3"	"2.8"	"8.0"	"7.7"	"5.8"	"3.7"	"36.5"	"31.8"	"32.0"	"40.2"	"66.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UQ84"	"Exonuclease 1 OS=Homo sapiens OX=9606 GN=EXO1 PE=1 SV=2"	"1"	"1"	"1"	"1"	"846"	"94.0"	"8.31"	"244.07"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00752, Pf00867"	"9156"	"ENSG00000174371"	"EXO1"	"hsa:9156; O60545; O75214; O75466; Q5T396; Q96IJ1; Q9UG38; Q9UNW0; Q9UQ84"	"DNA repair pathways, full network; DNA mismatch repair; Primary ovarian insufficiency"	"Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; Resolution of D-loop Structures through Holliday Junction Intermediates; Regulation of TP53 Activity through Phosphorylation; Presynaptic phase of homologous DNA pairing and strand exchange; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"19"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18615"	"Negative elongation factor E OS=Homo sapiens OX=9606 GN=NELFE PE=1 SV=3"	"5"	"1"	"1"	"1"	"380"	"43.2"	"9.33"	"243.91"	""	"1"	""	"other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"7936"	"ENSG00000204356; ENSG00000206268; ENSG00000206357; ENSG00000229363; ENSG00000231044; ENSG00000233801"	"NELFE"	"A2BE08; B4DUN1; B4DYX9; hsa:7936; P18615; Q5JP74; Q5JP75; Q96F56; Q9NPK2"	"Initiation of transcription and translation elongation at the HIV-1 LTR; 4p16.3 copy number variation"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes"	"16"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VTR2"	"E3 ubiquitin-protein ligase BRE1A OS=Homo sapiens OX=9606 GN=RNF20 PE=1 SV=2"	"1"	"1"	"1"	"1"	"975"	"113.6"	"5.94"	"242.99"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00097"	"56254"	"ENSG00000155827"	"RNF20"	"A7MCT5; hsa:56254; Q2TB34; Q5VTR2; Q69YL5; Q6P527; Q8N3J4; Q96JD3; Q9H9Y7; Q9HA51; Q9NUR4; Q9NWQ3; Q9NX83"	"ATM signaling in development and disease"	"RHOBTB1 GTPase cycle; E3 ubiquitin ligases ubiquitinate target proteins"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HCE1"	"Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2"	"1"	"1"	"1"	"1"	"1003"	"113.6"	"8.82"	"241.77"	""	"1"	""	"stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13087, Pf13604"	"4343"	"ENSG00000155363"	"MOV10"	"hsa:4343; Q5JR03; Q8TEF0; Q9BSY3; Q9BUJ9; Q9HCE1"	"VEGFA-VEGFR2 signaling"	"MAPK6/MAPK4 signaling; TP53 Regulates Metabolic Genes; Oxidative Stress Induced Senescence; Estrogen-dependent gene expression; Pre-NOTCH Transcription and Translation; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Oncogene Induced Senescence; Transcriptional Regulation by VENTX; Ca2+ pathway; Regulation of MECP2 expression and activity; NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux; Regulation of RUNX1 Expression and Activity; Regulation of CDH11 mRNA translation by microRNAs; Regulation of NPAS4 mRNA translation; Competing endogenous RNAs (ceRNAs) regulate PTEN translation"	"18"	"0"	"13.2"	"10.0"	"9.2"	"12.7"	"12.5"	"14.2"	"28.2"	"19.5"	"23.8"	"28.1"	"47.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IU60"	"m7GpppN-mRNA hydrolase OS=Homo sapiens OX=9606 GN=DCP2 PE=1 SV=3"	"1"	"1"	"1"	"1"	"420"	"48.4"	"8.00"	"241.11"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00293, Pf05026"	"167227"	"ENSG00000172795"	"DCP2"	"C9J778; hsa:167227; Q6P2D4; Q7Z5W5; Q8IU60; Q8NBG5"	""	"mRNA decay by 5' to 3' exoribonuclease; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"	"5"	"0"	"11.4"	"6.7"	"7.4"	"10.4"	"5.0"	"11.9"	"33.7"	"33.1"	"25.2"	"27.2"	"38.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z6R9"	"Transcription factor AP-2-delta OS=Homo sapiens OX=9606 GN=TFAP2D PE=1 SV=1"	"2"	"1"	"1"	"1"	"452"	"49.5"	"8.16"	"241.11"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03299"	"83741"	"ENSG00000008197"	"TFAP2D"	"hsa:83741; Q7Z6R9; Q8IWX0"	"Ciliary landscape"	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors; Activation of the TFAP2 (AP-2) family of transcription factors"	"3"	"0"	"73.8"	"36.2"	"164.7"	"71.3"	"55.9"	"71.1"	"153.9"	"117.2"	"89.7"	"156.4"	"169.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16555"	"Dihydropyrimidinase-related protein 2 OS=Homo sapiens OX=9606 GN=DPYSL2 PE=1 SV=1"	"2"	"1"	"1"	"1"	"572"	"62.3"	"6.38"	"241.00"	""	"1"	""	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton"	"other molecular function"	"Pf01979"	"1808"	"ENSG00000092964"	"DPYSL2"	"A8K5H2; B4DR31; D3DSS7; hsa:1808; O00424; Q16555"	"Microtubule cytoskeleton regulation; Brain-derived neurotrophic factor (BDNF) signaling pathway"	"CRMPs in Sema3A signaling; Recycling pathway of L1"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15434"	"RNA-binding motif, single-stranded-interacting protein 2 OS=Homo sapiens OX=9606 GN=RBMS2 PE=1 SV=1"	"1"	"1"	"1"	"1"	"407"	"43.9"	"9.07"	"239.14"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"5939"	"ENSG00000076067"	"RBMS2"	"hsa:5939; Q15434"	""	""	"0"	"0"	"23.3"	"9.5"	"17.6"	"15.6"	"14.9"	"24.5"	"39.5"	"39.6"	"26.7"	"42.6"	"43.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P02671"	"Fibrinogen alpha chain OS=Homo sapiens OX=9606 GN=FGA PE=1 SV=2"	"1"	"1"	"1"	"1"	"866"	"94.9"	"6.01"	"238.73"	""	"1"	""	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00147, Pf08702, Pf12160"	"2243"	"ENSG00000171560"	"FGA"	"A8K3E4; D3DP14; D3DP15; hsa:2243; P02671; Q4QQH7; Q9BX62; Q9UCH2"	"Selenium micronutrient network; Folate metabolism; Blood clotting cascade; Complement system; VEGFA-VEGFR2 signaling; Fibrin complement receptor 3 signaling pathway; COVID-19, thrombosis and anticoagulation; Network map of SARS-CoV-2 signaling pathway"	"ER-Phagosome pathway; Amyloid fiber formation; Integrin cell surface interactions; Platelet degranulation ; Signaling by BRAF and RAF1 fusions; MyD88:MAL(TIRAP) cascade initiated on plasma membrane; MyD88 deficiency (TLR2/4); IRAK4 deficiency (TLR2/4); Regulation of TLR by endogenous ligand; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; Common Pathway of Fibrin Clot Formation; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; GRB2:SOS provides linkage to MAPK signaling for Integrins ; p130Cas linkage to MAPK signaling for integrins"	"29"	"0"	"127.8"	"81.0"	"109.8"	"106.6"	"127.8"	"128.3"	"437.9"	"418.1"	"268.7"	"356.1"	"351.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H2J4"	"Phosducin-like protein 3 OS=Homo sapiens OX=9606 GN=PDCL3 PE=1 SV=1"	"5"	"1"	"1"	"1"	"239"	"27.6"	"4.84"	"238.37"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf02114"	"79031"	"ENSG00000115539"	"PDCL3"	"B2RA00; hsa:79031; Q53S68; Q9H2J4"	""	""	"0"	"0"	"15.6"	"10.1"	"19.1"	"15.3"	"12.4"	"15.5"	"24.1"	"24.2"	"27.9"	"29.5"	"52.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BZI7"	"Regulator of nonsense transcripts 3B OS=Homo sapiens OX=9606 GN=UPF3B PE=1 SV=1"	"2"	"1"	"1"	"1"	"483"	"57.7"	"9.48"	"238.22"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity"	"Pf03467"	"65109"	"ENSG00000125351"	"UPF3B"	"D3DWI3; D3DWI4; hsa:65109; Q0VAK8; Q9BZI7; Q9H1J0"	""	"mRNA Splicing - Major Pathway; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"6"	"0"	"15.2"	"11.8"	"15.4"	"17.7"	"17.8"	"20.4"	"40.5"	"34.4"	"19.6"	"42.9"	"55.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95825"	"Quinone oxidoreductase-like protein 1 OS=Homo sapiens OX=9606 GN=CRYZL1 PE=1 SV=2"	"6"	"1"	"1"	"1"	"349"	"38.7"	"5.78"	"237.87"	""	"1"	""	"other metabolic processes"	""	"other molecular function"	""	"9946"	"ENSG00000205758"	"CRYZL1"	"B2RDX1; B3KQ77; hsa:9946; O95825; Q96DY0; Q9NVY7"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14618"	"Copper chaperone for superoxide dismutase OS=Homo sapiens OX=9606 GN=CCS PE=1 SV=1"	"3"	"1"	"1"	"1"	"274"	"29.0"	"5.58"	"237.52"	""	"1"	""	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00080, Pf00403"	"9973"	"ENSG00000173992"	"CCS"	"hsa:9973; O14618; Q2M366; Q8NEV0"	"Amyotrophic lateral sclerosis (ALS); Copper homeostasis"	"Detoxification of Reactive Oxygen Species"	"3"	"0"	"45.3"	"29.8"	"53.9"	"54.5"	"48.0"	"53.8"	"94.7"	"80.7"	"46.8"	"87.9"	"166.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IXI1"	"Mitochondrial Rho GTPase 2 OS=Homo sapiens OX=9606 GN=RHOT2 PE=1 SV=2"	"2"	"1"	"1"	"1"	"618"	"68.1"	"5.86"	"237.20"	""	"1"	""	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf00071, Pf08355, Pf08356"	"89941"	"ENSG00000140983"	"RHOT2"	"A2IDC2; hsa:89941; Q8IXI1; Q8NF53; Q96C13; Q96S17; Q9BT60; Q9H7M8"	""	"RHOT2 GTPase cycle"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5B6"	"PAX3- and PAX7-binding protein 1 OS=Homo sapiens OX=9606 GN=PAXBP1 PE=1 SV=2"	"1"	"1"	"1"	"1"	"917"	"104.7"	"5.68"	"237.19"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf07842"	"94104"	"ENSG00000159086; ENSG00000263141"	"PAXBP1"	"D3DSE7; hsa:94104; Q96DU8; Q9NYQ0; Q9Y5B6"	""	""	"0"	"0"	"15.7"	"9.2"	"10.5"	"7.6"	"8.6"	"15.5"	"26.1"	"22.1"	"14.5"	"22.5"	"46.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3T9"	"Nucleolar complex protein 2 homolog OS=Homo sapiens OX=9606 GN=NOC2L PE=1 SV=4"	"2"	"1"	"1"	"1"	"749"	"84.9"	"5.62"	"237.04"	""	"1"	""	"cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf03715"	"26155"	"ENSG00000188976"	"NOC2L"	"hsa:26155; Q5SVA3; Q9BTN6; Q9Y3T9"	"1p36 copy number variation syndrome"	"Regulation of TP53 Activity through Phosphorylation"	"2"	"0"	"22.9"	"10.3"	"14.7"	"10.6"	"11.6"	"15.7"	"28.0"	"23.9"	"17.7"	"21.0"	"34.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5A9"	"YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2"	"1"	"1"	"1"	"1"	"579"	"62.3"	"8.79"	"236.24"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity"	"Pf04146"	"51441"	"ENSG00000198492"	"YTHDF2"	"A6NKG4; A8K966; B4E1G7; D3DPM8; hsa:51441; Q5VSZ9; Q8TDH0; Q9BUJ5; Q9Y5A9"	""	""	"0"	"0"	"14.0"	"9.5"	"9.5"	"13.1"	"13.1"	"10.0"	"85.7"	"80.4"	"67.1"	"86.2"	"109.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09884"	"DNA polymerase alpha catalytic subunit OS=Homo sapiens OX=9606 GN=POLA1 PE=1 SV=2"	"0"	"1"	"1"	"1"	"1462"	"165.8"	"5.85"	"235.06"	""	"1"	""	"cell cycle OR cell proliferation;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00136, Pf03104, Pf08996, Pf12254"	"5422"	"ENSG00000101868"	"POLA1"	"hsa:5422; P09884; Q86UQ7"	"Retinoblastoma gene in cancer; Pyrimidine metabolism; DNA replication"	"Activation of the pre-replicative complex; Defective pyroptosis; G1/S-Specific Transcription; Inhibition of replication initiation of damaged DNA by RB1/E2F1; Polymerase switching on the C-strand of the telomere; Telomere C-strand synthesis initiation; DNA replication initiation; Polymerase switching; Removal of the Flap Intermediate"	"13"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UH92"	"Max-like protein X OS=Homo sapiens OX=9606 GN=MLX PE=1 SV=2"	"2"	"1"	"1"	"1"	"298"	"33.3"	"8.06"	"234.92"	""	"1"	""	"other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00010"	"6945"	"ENSG00000108788"	"MLX"	"A8K2J3; B2RAV8; B2RD73; hsa:6945; Q53XM6; Q96FL2; Q9H2V0; Q9H2V1; Q9H2V2; Q9NXN3; Q9UH92"	"Nonalcoholic fatty liver disease"	"ChREBP activates metabolic gene expression"	"2"	"0"	"25.2"	"20.5"	"12.7"	"32.8"	"19.3"	"20.1"	"54.5"	"233.3"	"58.1"	"286.5"	"31.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96A65"	"Exocyst complex component 4 OS=Homo sapiens OX=9606 GN=EXOC4 PE=1 SV=1"	"1"	"1"	"1"	"1"	"974"	"110.4"	"6.49"	"234.90"	""	"1"	""	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf04048"	"60412"	"ENSG00000131558"	"EXOC4"	"E9PED2; hsa:60412; Q541U8; Q96A65; Q9C0G4; Q9H9K0; Q9P102"	"Ciliary landscape"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EK7"	"Constitutive coactivator of peroxisome proliferator-activated receptor gamma OS=Homo sapiens OX=9606 GN=FAM120B PE=1 SV=1"	"1"	"1"	"1"	"1"	"910"	"103.7"	"5.69"	"234.86"	""	"1"	""	"signal transduction;other biological processes"	"nucleus"	""	""	"84498"	"ENSG00000112584; ENSG00000275333"	"FAM120B"	"B4DL34; hsa:84498; Q86V68; Q96EK7; Q96JI9"	""	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z739"	"YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1"	"1"	"1"	"1"	"1"	"585"	"63.8"	"9.04"	"234.67"	""	"1"	""	"cell organization and biogenesis;other biological processes"	"cytosol;other cell component"	"translation activity;nucleic acid binding activity"	"Pf04146"	"253943"	"ENSG00000185728"	"YTHDF3"	"B3KXL4; hsa:253943; Q63Z37; Q659A3; Q7Z739"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T011"	"KICSTOR complex protein SZT2 OS=Homo sapiens OX=9606 GN=SZT2 PE=1 SV=3"	"0"	"1"	"1"	"1"	"3432"	"377.8"	"6.27"	"233.74"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;other biological processes"	"other membranes;other cytoplasmic organelle;other cell component"	""	""	"23334"	"ENSG00000198198"	"SZT2"	"A0PJK5; A7E2X4; hsa:23334; O75055; Q5JUY7; Q5T011; Q5T012; Q5XKC7; Q6ZNI8; Q6ZT24; Q7Z636; Q8NAY9; Q9H5H7; Q9UFQ8"	""	"Amino acids regulate mTORC1"	"1"	"0"	"32.5"	"20.8"	"25.7"	"37.4"	"31.6"	"40.8"	"66.9"	"58.5"	"45.9"	"64.3"	"84.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""