"Checked"	"Protein FDR Confidence: MS Amanda 2.0"	"Protein FDR Confidence: Sequest HT"	"Master"	"Accession"	"Description"	"Exp. q-value: MS Amanda 2.0"	"Exp. q-value: Sequest HT"	"Coverage [%]"	"# Peptides"	"# PSMs"	"# Unique Peptides"	"# AAs"	"MW [kDa]"	"calc. pI"	"Score MS Amanda 2.0: MS Amanda 2.0"	"Score Sequest HT: Sequest HT"	"# Peptides (by Search Engine): MS Amanda 2.0"	"# Peptides (by Search Engine): Sequest HT"	"Biological Process"	"Cellular Component"	"Molecular Function"	"Pfam IDs"	"Entrez Gene ID"	"Ensembl Gene ID"	"Gene Symbol"	"Gene ID"	"Reactome Pathways"	"WikiPathways"	"# Protein Pathway Groups"	"# Razor Peptides"	"Abundances (Grouped): 126"	"Abundances (Grouped): 127N"	"Abundances (Grouped): 127C"	"Abundances (Grouped): 128N"	"Abundances (Grouped): 128C"	"Abundances (Grouped): 129N"	"Abundances (Grouped): 129C"	"Abundances (Grouped): 130N"	"Abundances (Grouped): 130C"	"Abundances (Grouped): 131N"	"Abundances (Grouped): 131C"	"Abundances (Grouped) CV [%]: 126"	"Abundances (Grouped) CV [%]: 127N"	"Abundances (Grouped) CV [%]: 127C"	"Abundances (Grouped) CV [%]: 128N"	"Abundances (Grouped) CV [%]: 128C"	"Abundances (Grouped) CV [%]: 129N"	"Abundances (Grouped) CV [%]: 129C"	"Abundances (Grouped) CV [%]: 130N"	"Abundances (Grouped) CV [%]: 130C"	"Abundances (Grouped) CV [%]: 131N"	"Abundances (Grouped) CV [%]: 131C"	"Found in Sample: F7: 126, Sample"	"Found in Sample: F7: 127N, Sample"	"Found in Sample: F7: 127C, Sample"	"Found in Sample: F7: 128N, Sample"	"Found in Sample: F7: 128C, Sample"	"Found in Sample: F7: 129N, Sample"	"Found in Sample: F7: 129C, Sample"	"Found in Sample: F7: 130N, Sample"	"Found in Sample: F7: 130C, Sample"	"Found in Sample: F7: 131N, Sample"	"Found in Sample: F7: 131C, Sample"	"# Protein Groups"	"Modifications"
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13813"	"Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3"	"0.000"	""	"53"	"120"	"278"	"120"	"2472"	"284.4"	"5.35"	"41501.35"	"683.88"	"73"	"118"	"cell organization and biogenesis"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00018, Pf00435, Pf08726, Pf13499"	"6709"	"ENSG00000197694"	"SPTAN1"	"hsa:6709; Q13186; Q13813; Q15324; Q16606; Q59EF1; Q5VXV5; Q5VXV6; Q7Z6M5; Q9P0V0"	"Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Interaction between L1 and Ankyrins; RHOV GTPase cycle; RHOU GTPase cycle; Neutrophil degranulation; COPI-mediated anterograde transport; Nephrin family interactions; RAF/MAP kinase cascade; NCAM signaling for neurite out-growth; Caspase-mediated cleavage of cytoskeletal proteins"	"Fas ligand pathway and stress induction of heat shock proteins"	"12"	"0"	"9767.2"	"3841.3"	"7268.2"	"6172.9"	"7539.5"	"8204.6"	"6269.9"	"8856.5"	"8132.9"	"33421.1"	"107314.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01082"	"Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2"	"0.000"	""	"36"	"70"	"189"	"65"	"2364"	"274.4"	"5.57"	"36710.52"	"418.78"	"60"	"66"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00169, Pf00307, Pf00435"	"6711"	"ENSG00000115306"	"SPTBN1"	"B2RP63; hsa:6711; O60837; Q01082; Q16057; Q53R99; Q59ER3; Q8IX99"	"RAF/MAP kinase cascade; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; COPI-mediated anterograde transport; RHOV GTPase cycle; RHOU GTPase cycle; Nephrin family interactions; NCAM signaling for neurite out-growth; Interaction between L1 and Ankyrins; Signaling by FLT3 fusion proteins"	"Sudden infant death syndrome (SIDS) susceptibility pathways"	"11"	"5"	"5354.5"	"2189.5"	"4231.2"	"3657.0"	"4449.4"	"4934.8"	"3787.1"	"5203.8"	"4774.1"	"18477.1"	"54655.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08133"	"Annexin A6 OS=Homo sapiens OX=9606 GN=ANXA6 PE=1 SV=3"	"0.000"	""	"61"	"41"	"167"	"41"	"673"	"75.8"	"5.60"	"20974.81"	"386.94"	"32"	"40"	"cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;mitochondrion;other cytoplasmic organelle;other cell component"	"transporter activity;cytoskeletal activity;other molecular function"	"Pf00191"	"309"	"ENSG00000197043"	"ANXA6"	"B7Z8A7; D3DQH4; E9PGK1; hsa:309; P08133; Q6ZT79"	"Smooth Muscle Contraction"	"Calcium regulation in cardiac cells; Prostaglandin synthesis and regulation"	"3"	"0"	"2321.0"	"1001.1"	"2027.2"	"1592.0"	"2024.2"	"2169.8"	"1887.4"	"2828.7"	"3717.6"	"16978.8"	"88191.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23284"	"Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2"	"0.000"	""	"71"	"28"	"156"	"28"	"216"	"23.7"	"9.41"	"28424.14"	"283.66"	"25"	"26"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00160"	"5479"	"ENSG00000166794"	"PPIB"	"A8K534; hsa:5479; P23284; Q6IBH5; Q9BVK5"	"Collagen biosynthesis and modifying enzymes; SARS-CoV-1 activates/modulates innate immune responses"	"Prolactin signaling pathway; Type I collagen synthesis in the context of osteogenesis imperfecta"	"4"	"0"	"3582.4"	"2102.8"	"3426.6"	"3224.6"	"3477.6"	"4424.2"	"4816.1"	"11203.1"	"19937.8"	"51560.7"	"26017.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08670"	"Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4"	"0.000"	""	"73"	"44"	"159"	"42"	"466"	"53.6"	"5.12"	"31541.08"	"274.66"	"39"	"42"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00038, Pf04732"	"7431"	"ENSG00000026025"	"VIM"	"B0YJC2; D3DRU4; hsa:7431; P08670; Q15867; Q15868; Q15869; Q548L2; Q6LER9; Q8N850; Q96ML2; Q9NTM3"	"Aggrephagy; Late endosomal microautophagy; Interleukin-4 and Interleukin-13 signaling; Striated Muscle Contraction; RHOBTB1 GTPase cycle; Caspase-mediated cleavage of cytoskeletal proteins; Chaperone Mediated Autophagy"	"Allograft rejection; Spinal cord injury; Primary focal segmental glomerulosclerosis (FSGS); Mammary gland development pathway - Puberty (Stage 2 of 4); Apoptosis-related network due to altered Notch3 in ovarian cancer; Striated muscle contraction pathway; TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition; Ciliary landscape; Burn wound healing; CCL18 signaling pathway; TROP2 regulatory signaling; CKAP4 signaling pathway map; A network map of Macrophage-stimulating protein (MSP) signaling; T-cell receptor signaling pathway"	"21"	"2"	"12399.5"	"3759.8"	"6593.5"	"5286.3"	"7114.2"	"7611.9"	"5844.3"	"7964.6"	"6537.0"	"11157.4"	"19394.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22626"	"Heterogeneous nuclear ribonucleoproteins A2/B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2"	"0.000"	""	"82"	"25"	"122"	"23"	"353"	"37.4"	"8.95"	"19904.69"	"268.96"	"20"	"21"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"3181"	"ENSG00000122566"	"HNRNPA2B1"	"A0A024RA27; A0A024RA61; A8K064; hsa:3181; P22626; P22627; Q9UC98; Q9UDJ2"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"mRNA processing"	"4"	"3"	"14283.5"	"4170.4"	"7628.0"	"6166.9"	"7445.5"	"7943.2"	"6651.2"	"9188.8"	"7843.3"	"11836.7"	"20346.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P20700"	"Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2"	"0.000"	""	"68"	"46"	"139"	"41"	"586"	"66.4"	"5.16"	"24769.74"	"262.46"	"40"	"40"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytoskeleton;nucleus"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00038, Pf00932"	"4001"	"ENSG00000113368"	"LMNB1"	"B2R6J6; hsa:4001; P20700; Q3SYN7; Q96EI6"	"Meiotic synapsis; RHOD GTPase cycle; RHOF GTPase cycle; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models; Initiation of Nuclear Envelope (NE) Reformation; Depolymerization of the Nuclear Lamina; Breakdown of the nuclear lamina; Formation of Senescence-Associated Heterochromatin Foci (SAHF)"	"Fas ligand pathway and stress induction of heat shock proteins; Familial partial lipodystrophy; Progeria-associated lipodystrophy; Acquired partial lipodystrophy / Barraquer-Simons syndrome"	"14"	"6"	"11960.9"	"5160.9"	"9811.1"	"8053.2"	"9167.4"	"10401.7"	"7338.6"	"9548.9"	"8159.8"	"14609.4"	"22911.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q08211"	"ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4"	"0.000"	""	"38"	"42"	"131"	"42"	"1270"	"140.9"	"6.84"	"26239.67"	"246.37"	"38"	"36"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;cytoskeleton;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00035, Pf00270, Pf00271, Pf04408, Pf07717"	"1660"	"ENSG00000135829"	"DHX9"	"B2RNV4; hsa:1660; Q05CI5; Q08211; Q12803; Q32Q22; Q5VY62; Q6PD69; Q99556"	"mRNA Splicing - Major Pathway; RIP-mediated NFkB activation via ZBP1; DEx/H-box helicases activate type I IFN and inflammatory cytokines production"	"MECP2 and associated Rett syndrome; mRNA processing"	"5"	"0"	"5220.9"	"2229.3"	"4378.5"	"4022.4"	"3975.1"	"4941.5"	"3729.3"	"4876.1"	"5117.8"	"13828.7"	"27764.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61978"	"Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1"	"0.000"	""	"55"	"26"	"112"	"26"	"463"	"50.9"	"5.54"	"21068.35"	"216.82"	"21"	"25"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf08067"	"3190"	"ENSG00000165119"	"HNRNPK"	"hsa:3190; P61978; Q07244; Q15671; Q59F98; Q5T6W4; Q60577; Q6IBN1; Q922Y7; Q96J62"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA; HCMV Late Events; SUMOylation of RNA binding proteins"	"mRNA processing; lncRNA in canonical Wnt signaling and colorectal cancer"	"6"	"0"	"10502.7"	"4736.2"	"7365.3"	"6541.5"	"8050.4"	"8659.5"	"7393.8"	"9203.6"	"8227.5"	"11703.7"	"19973.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00159"	"Unconventional myosin-Ic OS=Homo sapiens OX=9606 GN=MYO1C PE=1 SV=4"	"0.000"	""	"43"	"41"	"96"	"40"	"1063"	"121.6"	"9.41"	"17626.83"	"208.23"	"35"	"38"	"cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00063, Pf00612, Pf06017"	"4641"	"ENSG00000197879"	"MYO1C"	"hsa:4641; O00159; Q4LE56; Q6NVJ7; Q86Y95"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Translocation of SLC2A4 (GLUT4) to the plasma membrane"	"VEGFA-VEGFR2 signaling; Insulin signaling; 10q11.21q11.23 copy number variation syndrome"	"8"	"1"	"1731.0"	"751.3"	"1514.4"	"1376.4"	"1593.6"	"2037.0"	"2190.2"	"4409.0"	"7397.8"	"18106.2"	"25616.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63010"	"AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1"	"0.000"	""	"38"	"37"	"115"	"21"	"937"	"104.5"	"5.38"	"20592.62"	"205.27"	"33"	"35"	"transport;developmental processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01602, Pf02883, Pf09066"	"163"	"ENSG00000006125"	"AP2B1"	"A6NJP3; hsa:163; P21851; P63010; Q7Z451; Q96J19"	"Recycling pathway of L1; MHC class II antigen presentation; Potential therapeutics for SARS; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; LDL clearance; Nef Mediated CD4 Down-regulation; Retrograde neurotrophin signalling; Nef Mediated CD8 Down-regulation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation"	"Synaptic vesicle pathway; GABA receptor signaling; EGF/EGFR signaling pathway; Fragile X syndrome; mBDNF and proBDNF regulation of GABA neurotransmission; Markers of kidney cell lineage; 17q12 copy number variation syndrome"	"20"	"21"	"2029.1"	"912.6"	"1852.2"	"1714.6"	"1859.2"	"2644.2"	"3908.7"	"11564.3"	"14662.0"	"25893.2"	"28975.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7KZF4"	"Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1"	"0.000"	""	"46"	"35"	"97"	"35"	"910"	"101.9"	"7.17"	"17450.78"	"199.55"	"29"	"34"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00565, Pf00567"	"27044"	"ENSG00000197157"	"SND1"	"hsa:27044; Q13122; Q7KZF4; Q96AG0"	"Signaling by BRAF and RAF1 fusions"	"VEGFA-VEGFR2 signaling"	"2"	"0"	"4732.6"	"2324.9"	"4109.8"	"3592.6"	"3779.8"	"4557.5"	"3616.1"	"4593.7"	"3849.2"	"9239.0"	"22077.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14683"	"Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2"	"0.000"	""	"38"	"50"	"102"	"49"	"1233"	"143.1"	"7.64"	"16211.74"	"183.36"	"39"	"45"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463, Pf06470"	"8243"	"ENSG00000072501"	"SMC1A"	"hsa:8243; O14995; Q14683; Q16351; Q2M228"	"Estrogen-dependent gene expression; Separation of Sister Chromatids; Meiotic synapsis; Resolution of Sister Chromatid Cohesion; SUMOylation of DNA damage response and repair proteins; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"miRNA regulation of DNA damage response; Cell cycle; Retinoblastoma gene in cancer; Constitutive androstane receptor pathway; Nuclear receptors meta-pathway; Pathways affected in adenoid cystic carcinoma; ATM signaling in development and disease ; mRNA processing; Regulation of sister chromatid separation at the metaphase-anaphase transition; Rett syndrome causing genes; CAMKK2 pathway; Cohesin complex - Cornelia de Lange syndrome; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; 10q22q23 copy number variation; DNA damage response"	"22"	"1"	"5237.2"	"2242.9"	"4639.8"	"4048.9"	"4598.0"	"5297.5"	"3607.6"	"5046.9"	"3998.6"	"14124.8"	"37346.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75643"	"U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2"	"0.000"	""	"25"	"49"	"105"	"49"	"2136"	"244.4"	"6.06"	"19045.23"	"174.89"	"45"	"41"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00270, Pf00271, Pf02889, Pf18149"	"23020"	"ENSG00000144028"	"SNRNP200"	"hsa:23020; O75643; O94884; Q6NZY0; Q6PX59; Q8NBE6; Q96IF2; Q9H7S0"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"2q11.2 copy number variation syndrome"	"3"	"0"	"4912.3"	"1735.4"	"3671.3"	"3306.2"	"3712.2"	"4330.0"	"3012.4"	"4151.9"	"3055.6"	"6361.7"	"15082.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P04406"	"Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3"	"0.000"	""	"64"	"20"	"65"	"20"	"335"	"36.0"	"8.46"	"10374.94"	"161.88"	"13"	"18"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00044, Pf02800"	"2597"	"ENSG00000111640"	"GAPDH"	"E7EUT4; hsa:2597; P00354; P04406; Q53X65"	"Glycolysis; Gluconeogenesis"	"Cori cycle; Alzheimer's disease and miRNA effects; HIF1A and PPARG regulation of glycolysis; VEGFA-VEGFR2 signaling; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; 7q11.23 copy number variation syndrome; Glycolysis in senescence; Alzheimer's disease; Sildenafil treatment; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders; Sudden infant death syndrome (SIDS) susceptibility pathways"	"16"	"0"	"5440.5"	"2561.2"	"4783.9"	"3940.6"	"4753.6"	"5608.5"	"3912.2"	"5086.6"	"3708.6"	"6287.5"	"12690.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95602"	"DNA-directed RNA polymerase I subunit RPA1 OS=Homo sapiens OX=9606 GN=POLR1A PE=1 SV=2"	"0.000"	""	"28"	"35"	"64"	"34"	"1720"	"194.7"	"7.03"	"10092.95"	"159.14"	"20"	"34"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00623, Pf04983, Pf04997, Pf04998, Pf05000"	"25885"	"ENSG00000068654"	"POLR1A"	"B7Z7T0; D6W5M0; hsa:25885; O95602; Q0VG05; Q9UEH0; Q9UFT9"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"Pyrimidine metabolism; Eukaryotic transcription initiation; 2q13 copy number variation syndrome"	"8"	"1"	"1075.2"	"455.7"	"993.4"	"876.9"	"1028.1"	"1125.3"	"869.9"	"2027.8"	"4497.3"	"14144.9"	"24752.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11142"	"Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1"	"0.000"	""	"55"	"32"	"90"	"26"	"646"	"70.9"	"5.52"	"16317.86"	"158.05"	"27"	"30"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00012"	"3312"	"ENSG00000109971"	"HSPA8"	"hsa:3312; P11142; Q9H3R6"	"AUF1 (hnRNP D0) binds and destabilizes mRNA; Neutrophil degranulation; mRNA Splicing - Major Pathway; Clathrin-mediated endocytosis; Late endosomal microautophagy; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Regulation of HSF1-mediated heat shock response; Lysosome Vesicle Biogenesis; Golgi Associated Vesicle Biogenesis; CHL1 interactions; Interleukin-4 and Interleukin-13 signaling; GABA synthesis, release, reuptake and degradation; Lipophagy; Chaperone Mediated Autophagy; Protein methylation; Attenuation phase"	"Parkin-ubiquitin proteasomal system pathway; MAPK signaling pathway; Exercise-induced circadian regulation; Measles virus infection; Opioid receptor pathways; Extrafollicular and follicular B cell activation by SARS-CoV-2; 1p36 copy number variation syndrome"	"24"	"7"	"6187.1"	"2793.9"	"5477.8"	"4679.7"	"5485.5"	"6202.4"	"4469.0"	"6218.2"	"4624.7"	"9132.0"	"20179.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P54577"	"Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4"	"0.000"	""	"61"	"29"	"66"	"29"	"528"	"59.1"	"7.05"	"8042.21"	"157.43"	"15"	"28"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00579, Pf01588"	"8565"	"ENSG00000134684"	"YARS1"	"B3KWK4; D3DPQ4; hsa:8565; O43276; P54577; Q53EN1"	"Cytosolic tRNA aminoacylation"	"Nephrotic syndrome"	"2"	"0"	"1858.5"	"996.2"	"1592.4"	"1378.0"	"1652.6"	"1814.2"	"1515.4"	"2004.7"	"3023.1"	"15539.5"	"33761.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92841"	"Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2"	"0.000"	""	"44"	"31"	"93"	"22"	"729"	"80.2"	"8.27"	"16679.65"	"157.21"	"29"	"30"	"RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"10521"	"ENSG00000100201"	"DDX17"	"B1AHM0; H3BLZ8; hsa:10521; Q69YT1; Q6ICD6; Q92841"	"SUMOylation of transcription cofactors"	"Novel intracellular components of RIG-I-like receptor pathway"	"2"	"10"	"6378.3"	"2147.5"	"4163.3"	"3281.5"	"3863.3"	"4411.8"	"3263.0"	"4553.0"	"4008.6"	"7223.3"	"9839.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94973"	"AP-2 complex subunit alpha-2 OS=Homo sapiens OX=9606 GN=AP2A2 PE=1 SV=2"	"0.000"	""	"35"	"29"	"83"	"21"	"939"	"103.9"	"6.96"	"14676.28"	"153.45"	"24"	"27"	"transport"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01602, Pf02296, Pf02883"	"161"	"ENSG00000183020"	"AP2A2"	"hsa:161; O75403; O94973; Q53ET1; Q96SI8"	"Neutrophil degranulation; Potential therapeutics for SARS; Recycling pathway of L1; MHC class II antigen presentation; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; LDL clearance; Nef Mediated CD4 Down-regulation; Retrograde neurotrophin signalling; Nef Mediated CD8 Down-regulation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation"	"Synaptic vesicle pathway; GABA receptor signaling; mBDNF and proBDNF regulation of GABA neurotransmission"	"17"	"7"	"1132.5"	"555.5"	"1103.2"	"1009.5"	"1135.1"	"1564.2"	"2438.0"	"8207.8"	"10740.4"	"18939.8"	"20025.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35637"	"RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1"	"0.000"	""	"28"	"18"	"65"	"15"	"526"	"53.4"	"9.36"	"11723.38"	"152.81"	"11"	"16"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00641"	"2521"	"ENSG00000089280"	"FUS"	"hsa:2521; P35637; Q9H4A8"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"MECP2 and associated Rett syndrome; mRNA processing"	"4"	"4"	"7341.3"	"3619.5"	"5265.3"	"4359.2"	"4959.5"	"5509.6"	"4440.6"	"5617.0"	"4551.1"	"6573.2"	"10264.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43491"	"Band 4.1-like protein 2 OS=Homo sapiens OX=9606 GN=EPB41L2 PE=1 SV=1"	"0.000"	""	"39"	"32"	"77"	"27"	"1005"	"112.5"	"5.44"	"14047.03"	"151.71"	"28"	"27"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf04382, Pf05902, Pf08736, Pf09379, Pf09380"	"2037"	"ENSG00000079819"	"EPB41L2"	"B4DHI8; E9PPD9; hsa:2037; O43491; Q5T4F0; Q68DV2"	"Neurexins and neuroligins"	"Splicing factor NOVA regulated synaptic proteins"	"2"	"6"	"3656.8"	"1760.7"	"3550.6"	"3083.5"	"3366.5"	"4101.2"	"3294.6"	"4523.2"	"4682.6"	"21901.8"	"25354.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12906"	"Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3"	"0.000"	""	"41"	"30"	"80"	"26"	"894"	"95.3"	"8.76"	"14251.68"	"151.36"	"25"	"28"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00035, Pf07528"	"3609"	"ENSG00000129351"	"ILF3"	"A8K6F2; G5E9M5; hsa:3609; O43409; Q12906; Q6P1X1; Q86XY7; Q99544; Q99545; Q9BZH4; Q9BZH5; Q9NQ95; Q9NQ96; Q9NQ97; Q9NQ98; Q9NQ99; Q9NQA0; Q9NQA1; Q9NQA2; Q9NRN2; Q9NRN3; Q9NRN4; Q9UMZ9; Q9UN00; Q9UN84; Q9UNA2"	"Regulation of CDH11 gene transcription"	""	"1"	"4"	"5729.3"	"1699.5"	"3521.1"	"2996.0"	"3633.6"	"4160.0"	"3133.7"	"4154.2"	"3612.5"	"5655.6"	"9567.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P04264"	"Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6"	"0.000"	""	"40"	"23"	"74"	"19"	"644"	"66.0"	"8.12"	"11490.59"	"147.60"	"20"	"23"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"bone, tooth or skin structural activity;other molecular function"	"Pf00038, Pf16208, Pf16210"	"3848"	"ENSG00000167768"	"KRT1"	"B2RA01; hsa:3848; P04264; P85925; P86104; Q14720; Q6GSJ0; Q9H298"	"Formation of the cornified envelope; Neutrophil degranulation"	"Corticotropin-releasing hormone signaling pathway"	"4"	"4"	"1486.9"	"5696.8"	"2951.3"	"927.7"	"7718.6"	"1494.8"	"1234.9"	"2088.8"	"6593.5"	"5397.7"	"10355.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95782"	"AP-2 complex subunit alpha-1 OS=Homo sapiens OX=9606 GN=AP2A1 PE=1 SV=3"	"0.000"	""	"34"	"28"	"76"	"20"	"977"	"107.5"	"7.03"	"11663.35"	"147.40"	"25"	"26"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01602, Pf02296, Pf02883"	"160"	"ENSG00000196961"	"AP2A1"	"hsa:160; O95782; Q96CI7; Q96PP6; Q96PP7; Q9H070"	"MHC class II antigen presentation; Potential therapeutics for SARS; Recycling pathway of L1; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; LDL clearance; Trafficking of GluR2-containing AMPA receptors; Nef Mediated CD4 Down-regulation; Retrograde neurotrophin signalling; Nef Mediated CD8 Down-regulation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation"	"Synaptic vesicle pathway; VEGFA-VEGFR2 signaling; GABA receptor signaling; EGF/EGFR signaling pathway; Fragile X syndrome; mBDNF and proBDNF regulation of GABA neurotransmission"	"20"	"0"	"822.9"	"389.2"	"782.2"	"681.5"	"767.1"	"1008.1"	"1274.0"	"3660.2"	"5440.4"	"8911.4"	"10746.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P2Q9"	"Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2"	"0.000"	""	"22"	"45"	"83"	"45"	"2335"	"273.4"	"8.84"	"14544.58"	"143.25"	"39"	"40"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01398, Pf08082, Pf08083, Pf08084, Pf10596, Pf10597, Pf10598, Pf12134"	"10594"	"ENSG00000174231; ENSG00000274442"	"PRPF8"	"hsa:10594; O14547; O75965; Q6P2Q9"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"mRNA processing"	"3"	"0"	"7025.1"	"2318.8"	"4969.1"	"4255.9"	"4786.3"	"5660.9"	"4048.1"	"5425.7"	"4245.3"	"8704.6"	"18974.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UQE7"	"Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2"	"0.000"	""	"32"	"39"	"78"	"39"	"1217"	"141.5"	"7.18"	"12431.14"	"141.28"	"30"	"37"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf02463, Pf06470"	"9126"	"ENSG00000108055"	"SMC3"	"A8K156; hsa:9126; O60464; Q5T482; Q9UQE7"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Estrogen-dependent gene expression; SUMOylation of DNA damage response and repair proteins; Meiotic synapsis; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"Cell cycle; Retinoblastoma gene in cancer; MECP2 and associated Rett syndrome; Prion disease pathway; Regulation of sister chromatid separation at the metaphase-anaphase transition; Cohesin complex - Cornelia de Lange syndrome; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; 10q22q23 copy number variation"	"15"	"0"	"5108.7"	"2082.8"	"4495.6"	"3858.1"	"4396.5"	"5128.6"	"3569.2"	"4944.0"	"3580.5"	"13372.6"	"36401.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96CW1"	"AP-2 complex subunit mu OS=Homo sapiens OX=9606 GN=AP2M1 PE=1 SV=2"	"0.000"	""	"50"	"22"	"76"	"22"	"435"	"49.6"	"9.54"	"14846.55"	"140.53"	"21"	"20"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00928, Pf01217"	"1173"	"ENSG00000161203"	"AP2M1"	"A6NE12; D3DNT1; hsa:1173; P20172; P53679; Q96CW1"	"Potential therapeutics for SARS; EPH-ephrin mediated repulsion of cells; Cargo recognition for clathrin-mediated endocytosis; VLDLR internalisation and degradation; Recycling pathway of L1; MHC class II antigen presentation; WNT5A-dependent internalization of FZD4; LDL clearance; Nef Mediated CD4 Down-regulation; Retrograde neurotrophin signalling; Nef Mediated CD8 Down-regulation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; Nef mediated downregulation of CD28 cell surface expression; Formation of annular gap junctions"	"Synaptic vesicle pathway; GABA receptor signaling; EGF/EGFR signaling pathway; Fragile X syndrome; GDNF signaling"	"21"	"0"	"1035.3"	"476.0"	"934.7"	"840.2"	"971.9"	"1175.3"	"1600.6"	"4574.6"	"6644.1"	"10942.5"	"11115.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P31943"	"Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4"	"0.000"	""	"43"	"16"	"66"	"7"	"449"	"49.2"	"6.30"	"11047.96"	"140.44"	"13"	"15"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08080"	"3187"	"ENSG00000169045; ENSG00000284254"	"HNRNPH1"	"B3KW86; D3DWQ2; hsa:3187; P31943; Q6IBM4"	"mRNA Splicing - Major Pathway; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA"	"MECP2 and associated Rett syndrome; mRNA processing; Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells"	"6"	"8"	"3997.7"	"1851.5"	"4187.7"	"3299.5"	"3229.1"	"3949.6"	"2875.0"	"4015.2"	"3113.4"	"5324.4"	"7162.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q03252"	"Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4"	"0.000"	""	"43"	"33"	"83"	"27"	"620"	"69.9"	"5.59"	"14362.74"	"139.07"	"31"	"30"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytoskeleton;nucleus"	"cytoskeletal activity;other molecular function"	"Pf00038, Pf00932"	"84823"	"ENSG00000176619"	"LMNB2"	"hsa:84823; O75292; Q03252; Q14734; Q96DF6"	""	"Gastric cancer network 2; Fas ligand pathway and stress induction of heat shock proteins; IL-18 signaling pathway; Familial partial lipodystrophy; Progeria-associated lipodystrophy; Acquired partial lipodystrophy / Barraquer-Simons syndrome"	"6"	"1"	"6234.4"	"2538.1"	"5249.2"	"4160.1"	"4958.9"	"5636.5"	"4093.5"	"5361.2"	"4195.6"	"8017.7"	"12230.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09874"	"Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4"	"0.000"	""	"31"	"26"	"60"	"26"	"1014"	"113.0"	"8.88"	"8737.85"	"138.92"	"14"	"25"	"cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00533, Pf00644, Pf00645, Pf02877, Pf05406, Pf08063"	"142"	"ENSG00000143799"	"PARP1"	"B1ANJ4; hsa:142; P09874; Q8IUZ9"	"SUMOylation of DNA damage response and repair proteins; Downregulation of SMAD2/3:SMAD4 transcriptional activity; HDR through MMEJ (alt-NHEJ); Formation of Incision Complex in GG-NER; DNA Damage Recognition in GG-NER; vRNA Synthesis; POLB-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER"	"Corticotropin-releasing hormone signaling pathway; Nanoparticle triggered regulated necrosis; Fas ligand pathway and stress induction of heat shock proteins; NAD metabolism, sirtuins and aging; NAD+ metabolism; NAD+ biosynthetic pathways; Breast cancer pathway; Acute viral myocarditis; Joubert syndrome; Male infertility; Base excision repair; IL-18 signaling pathway; DNA repair pathways, full network; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Progeria-associated lipodystrophy; Primary ovarian insufficiency; A network map of Macrophage-stimulating protein (MSP) signaling"	"25"	"0"	"1794.5"	"826.4"	"1412.1"	"1170.2"	"1342.5"	"1664.3"	"1286.6"	"1843.5"	"2171.3"	"9644.2"	"26007.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2J2"	"Band 4.1-like protein 3 OS=Homo sapiens OX=9606 GN=EPB41L3 PE=1 SV=2"	"0.000"	""	"24"	"26"	"62"	"20"	"1087"	"120.6"	"5.19"	"11664.14"	"127.78"	"23"	"23"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf04382, Pf05902, Pf08736, Pf09379, Pf09380"	"23136"	"ENSG00000082397"	"EPB41L3"	"B7Z4I5; F5GX05; hsa:23136; O95713; Q9BRP5; Q9Y2J2"	"Neurexins and neuroligins; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea"	"Splicing factor NOVA regulated synaptic proteins"	"4"	"1"	"1310.4"	"643.5"	"1247.3"	"1120.3"	"1209.7"	"1416.5"	"1074.4"	"1520.3"	"2545.0"	"14086.9"	"16361.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TAF3"	"WD repeat-containing protein 48 OS=Homo sapiens OX=9606 GN=WDR48 PE=1 SV=1"	"0.000"	""	"53"	"29"	"60"	"29"	"677"	"76.2"	"7.03"	"9331.56"	"127.00"	"21"	"27"	"DNA metabolism;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00400, Pf11816"	"57599"	"ENSG00000114742"	"WDR48"	"B4DM86; B4DQI2; B4DY84; hsa:57599; Q63HJ2; Q658Y1; Q8N3Z1; Q8TAF3; Q9NSK8; Q9P279"	"Ub-specific processing proteases; Recognition of DNA damage by PCNA-containing replication complex; Fanconi Anemia Pathway; Signaling by cytosolic PDGFRA and PDGFRB fusion proteins"	"DNA repair pathways, full network"	"5"	"0"	"1234.7"	"557.8"	"1084.7"	"1005.3"	"1097.7"	"1282.1"	"1216.0"	"2493.2"	"4052.6"	"12883.1"	"12272.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7KZ85"	"Transcription elongation factor SPT6 OS=Homo sapiens OX=9606 GN=SUPT6H PE=1 SV=2"	"0.000"	""	"22"	"35"	"68"	"35"	"1726"	"198.9"	"4.91"	"11703.39"	"125.48"	"28"	"29"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00575, Pf14632, Pf14633, Pf14635, Pf14639, Pf14641, Pf17674"	"6830"	"ENSG00000109111"	"SUPT6H"	"A7E2B4; hsa:6830; Q15737; Q6GMQ4; Q7KYW9; Q7KZ85; Q7LDK4; Q8N526; Q92775; Q96AH3; Q9BTH9; Q9BTI2"	"Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events"	""	"3"	"0"	"4143.1"	"1849.3"	"3662.6"	"3175.2"	"3634.3"	"4214.3"	"3170.1"	"4097.7"	"3081.9"	"5399.7"	"9344.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14866"	"Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2"	"0.000"	""	"39"	"14"	"53"	"13"	"589"	"64.1"	"8.22"	"9856.33"	"123.04"	"11"	"14"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf11835, Pf13893"	"3191"	"ENSG00000104824; ENSG00000282947"	"HNRNPL"	"A6ND69; A6NIT8; hsa:3191; P14866; Q9H3P3"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"mRNA processing; Hippocampal synaptogenesis and neurogenesis"	"4"	"2"	"5477.9"	"1657.4"	"3287.6"	"2909.7"	"3008.3"	"3425.6"	"2903.5"	"3461.9"	"3053.4"	"4541.2"	"6726.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51991"	"Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2"	"0.000"	""	"46"	"16"	"62"	"14"	"378"	"39.6"	"9.01"	"10533.91"	"122.26"	"12"	"15"	"RNA metabolism OR transcription;other metabolic processes;transport"	"nucleus;other cell component"	"transporter activity;nucleic acid binding activity"	"Pf00076"	"220988"	"ENSG00000170144"	"HNRNPA3"	"D3DPF4; hsa:220988; P51991; Q53RW7; Q6URK5"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	""	"2"	"0"	"4792.4"	"1527.8"	"2931.4"	"2492.1"	"2766.4"	"3126.9"	"2580.5"	"3210.3"	"2800.6"	"4423.1"	"6803.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07910"	"Heterogeneous nuclear ribonucleoproteins C1/C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4"	"0.000"	""	"37"	"19"	"81"	"19"	"306"	"33.7"	"5.08"	"16682.47"	"121.78"	"18"	"15"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"3183"	"ENSG00000092199"	"HNRNPC"	"D3DS19; D3DS22; hsa:3183; P07910; P22628; Q53EX2; Q59FD3; Q5FWE8; Q86SF8; Q86U45; Q96HK7; Q96HM4; Q96IY5; Q9BTS3"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA; SUMOylation of RNA binding proteins; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle"	"mRNA processing"	"6"	"0"	"8925.9"	"2772.3"	"4960.5"	"3993.2"	"4967.7"	"5431.4"	"4527.4"	"5668.6"	"5158.1"	"7335.4"	"10747.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46940"	"Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1"	"0.000"	""	"19"	"24"	"43"	"23"	"1657"	"189.1"	"6.48"	"5941.01"	"120.74"	"12"	"23"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00307, Pf00612, Pf00616, Pf03836"	"8826"	"ENSG00000140575"	"IQGAP1"	"A7MBM3; hsa:8826; P46940"	"Signaling by BRAF and RAF1 fusions; Neutrophil degranulation; RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHO GTPases activate IQGAPs; RAC2 GTPase cycle; RHOV GTPase cycle; RHOU GTPase cycle; Nephrin family interactions; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants"	"VEGFA-VEGFR2 signaling; Ebola virus infection in host; Ciliary landscape; EGF/EGFR signaling pathway; Regulation of actin cytoskeleton; G13 signaling pathway"	"25"	"1"	"561.5"	"235.6"	"505.5"	"436.8"	"504.1"	"552.1"	"425.9"	"590.0"	"745.0"	"4316.3"	"14072.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13435"	"Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2"	"0.000"	""	"25"	"20"	"60"	"20"	"895"	"100.2"	"5.67"	"11348.42"	"119.01"	"19"	"19"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf02037, Pf04037, Pf04046"	"10992"	"ENSG00000087365"	"SF3B2"	"A8K485; B4DT19; hsa:10992; Q13435; Q7L4T5; Q7Z627; Q969K1; Q96CM6; Q9BWD2"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"mRNA processing"	"3"	"0"	"3147.2"	"1246.9"	"2588.2"	"2153.2"	"2387.1"	"2915.7"	"1929.2"	"2664.2"	"2016.6"	"3540.8"	"5967.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P02545"	"Prelamin-A/C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1"	"0.000"	""	"35"	"30"	"79"	"27"	"664"	"74.1"	"7.02"	"14484.71"	"118.53"	"30"	"27"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00038, Pf00932"	"4000"	"ENSG00000160789"	"LMNA"	"B4DI32; D3DVB0; D6RAQ3; E7EUI9; hsa:4000; P02545; P02546; Q5I6Y4; Q5I6Y6; Q5TCJ2; Q5TCJ3; Q6UYC3; Q969I8; Q96JA2"	"XBP1(S) activates chaperone genes; Signaling by BRAF and RAF1 fusions"	"Arrhythmogenic right ventricular cardiomyopathy; Adipogenesis; Fas ligand pathway and stress induction of heat shock proteins; Lamin A-processing pathway; Nephrotic syndrome; Influence of laminopathies on Wnt signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies; Familial partial lipodystrophy; Progeria-associated lipodystrophy; Acquired partial lipodystrophy / Barraquer-Simons syndrome; Primary ovarian insufficiency"	"13"	"0"	"6996.3"	"3114.7"	"6145.9"	"5033.1"	"5904.9"	"7110.9"	"4800.0"	"6146.2"	"5094.1"	"9135.0"	"12345.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14103"	"Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1"	"0.000"	""	"44"	"21"	"70"	"17"	"355"	"38.4"	"7.81"	"13008.02"	"118.43"	"19"	"18"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08143"	"3184"	"ENSG00000138668"	"HNRNPD"	"A8K9J2; hsa:3184; P07029; Q01858; Q14100; Q14101; Q14102; Q14103; Q4W5A1; Q9UCE8; Q9UCE9"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"mRNA processing"	"3"	"6"	"7240.2"	"2376.9"	"4848.9"	"4052.7"	"4459.3"	"5601.5"	"4435.1"	"5778.2"	"5032.6"	"7616.2"	"9733.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P32121"	"Beta-arrestin-2 OS=Homo sapiens OX=9606 GN=ARRB2 PE=1 SV=2"	"0.000"	""	"59"	"22"	"51"	"18"	"409"	"46.1"	"7.69"	"7921.07"	"118.17"	"17"	"20"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00339, Pf02752"	"409"	"ENSG00000141480"	"ARRB2"	"B4DLW0; B5B0C0; B7WPL3; D3DTK2; H0Y688; hsa:409; P32121; Q0Z8D3; Q2PP19; Q6ICT3; Q8N7Y2; Q9UEQ6"	"Ub-specific processing proteases; Activation of SMO; Activated NOTCH1 Transmits Signal to the Nucleus; G alpha (s) signalling events; Signaling by BRAF and RAF1 fusions; Thrombin signalling through proteinase activated receptors (PARs); Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants"	"Corticotropin-releasing hormone signaling pathway; Complement system; Myometrial relaxation and contraction pathways; Wnt signaling pathway; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Hedgehog signaling pathway; Gastrin signaling pathway; Kisspeptin/kisspeptin receptor system in the ovary; GPR143 in melanocytes and retinal pigment epithelium cells; Calcium regulation in cardiac cells"	"27"	"4"	"734.3"	"319.4"	"654.2"	"650.5"	"732.5"	"1364.5"	"2487.6"	"5913.2"	"6926.6"	"10715.1"	"9322.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P12270"	"Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3"	"0.000"	""	"17"	"37"	"68"	"37"	"2363"	"267.1"	"5.02"	"13675.22"	"118.04"	"33"	"31"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"other membranes;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf07926"	"7175"	"ENSG00000047410"	"TPR"	"hsa:7175; P12270; Q15624; Q15655; Q5SWY0; Q99968"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; Signaling by ALK fusions and activated point mutants; HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	""	"29"	"0"	"5380.8"	"1766.9"	"4025.2"	"3264.5"	"3996.9"	"4500.3"	"2995.5"	"4411.6"	"3075.4"	"6652.6"	"14322.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P06748"	"Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2"	"0.000"	""	"51"	"16"	"69"	"16"	"294"	"32.6"	"4.78"	"12620.08"	"117.51"	"14"	"16"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;translation activity;nucleic acid binding activity;other molecular function"	"Pf03066, Pf16276"	"4869"	"ENSG00000181163"	"NPM1"	"A8K3N7; B5BU00; D3DQL6; hsa:4869; P06748; P08693; Q12826; Q13440; Q13441; Q14115; Q5EU94; Q5EU95; Q5EU96; Q5EU97; Q5EU98; Q5EU99; Q6V962; Q8WTW5; Q96AT6; Q96DC4; Q96EA5; Q9BYG9; Q9UDJ7"	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain; Nuclear import of Rev protein; Deposition of new CENPA-containing nucleosomes at the centromere; SUMOylation of transcription cofactors; ALK mutants bind TKIs; Nuclear events stimulated by ALK signaling in cancer; TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation; SARS-CoV-1-host interactions"	""	"9"	"0"	"8263.7"	"4564.0"	"8082.5"	"7941.6"	"7249.1"	"9026.9"	"7165.8"	"8961.1"	"6454.6"	"10972.2"	"27020.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VT25"	"Serine/threonine-protein kinase MRCK alpha OS=Homo sapiens OX=9606 GN=CDC42BPA PE=1 SV=1"	"0.000"	""	"20"	"29"	"62"	"25"	"1732"	"197.2"	"6.58"	"11013.02"	"117.48"	"24"	"24"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00130, Pf00433, Pf00780, Pf08826, Pf15796"	"8476"	"ENSG00000143776"	"CDC42BPA"	"hsa:8476; O75039; Q59GZ1; Q5H9N9; Q5T797; Q5VT25; Q5VT26; Q5VT27; Q86XX2; Q86XX3; Q99646"	"CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHOJ GTPase cycle"	"Male infertility"	"5"	"3"	"1175.7"	"459.7"	"947.3"	"805.4"	"991.3"	"1206.9"	"1571.4"	"4036.0"	"5127.2"	"13500.5"	"18561.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P0DMV9"	"Heat shock 70 kDa protein 1B OS=Homo sapiens OX=9606 GN=HSPA1B PE=1 SV=1"	"0.000"	""	"43"	"26"	"61"	"20"	"641"	"70.0"	"5.66"	"10409.07"	"116.81"	"21"	"24"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00012"	"3303; 3304"	"ENSG00000204388; ENSG00000212866; ENSG00000224501; ENSG00000231555; ENSG00000232804"	"HSPA1B"	"B4E3B6; hsa:3303; hsa:3304; P08107; P0DMV9; P19790; Q5JQI4; Q5SP17; Q9UQL9; Q9UQM0"	"Neutrophil degranulation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Regulation of HSF1-mediated heat shock response; Attenuation phase"	"Apoptosis modulation and signaling; Parkin-ubiquitin proteasomal system pathway; MAPK signaling pathway; Apoptosis modulation by HSP70; VEGFA-VEGFR2 signaling; Measles virus infection; CKAP4 signaling pathway map"	"12"	"0"	"3706.9"	"1704.5"	"3697.9"	"3282.4"	"3507.7"	"4097.7"	"2875.0"	"3824.1"	"2601.8"	"5172.5"	"10959.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q00839"	"Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6"	"0.000"	""	"32"	"28"	"63"	"27"	"825"	"90.5"	"6.00"	"12296.02"	"116.57"	"20"	"21"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00622, Pf02037, Pf13671"	"3192"	"ENSG00000153187"	"HNRNPU"	"hsa:3192; O75507; Q00839; Q8N174; Q96HY9; Q9BQ09"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"mRNA processing; lncRNA in canonical Wnt signaling and colorectal cancer"	"4"	"1"	"11591.1"	"2361.4"	"5828.3"	"4582.9"	"5593.0"	"6206.9"	"5066.3"	"6345.5"	"5377.0"	"8811.8"	"18504.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WXH0"	"Nesprin-2 OS=Homo sapiens OX=9606 GN=SYNE2 PE=1 SV=3"	"0.000"	""	"6"	"29"	"44"	"28"	"6885"	"795.9"	"5.36"	"6212.56"	"116.45"	"12"	"28"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00435, Pf10541"	"23224"	"ENSG00000054654"	"SYNE2"	"B4DND7; B4DPR6; hsa:23224; I6XXQ5; Q540G1; Q86YP9; Q8N1S3; Q8NF49; Q8TER7; Q8WWW3; Q8WWW4; Q8WWW5; Q8WXH0; Q8WXH1; Q9NU50; Q9UFQ4; Q9Y2L4; Q9Y4R1"	"Meiotic synapsis"	"Ovarian infertility; Rett syndrome causing genes; Envelope proteins and their potential roles in EDMD physiopathology"	"4"	"1"	"1014.6"	"413.4"	"814.9"	"649.9"	"802.1"	"870.6"	"711.3"	"964.0"	"1041.4"	"4622.2"	"12458.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15459"	"Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1"	"0.000"	""	"40"	"26"	"57"	"26"	"793"	"88.8"	"5.22"	"11616.30"	"113.95"	"24"	"25"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00240, Pf01805, Pf12230"	"10291"	"ENSG00000099995"	"SF3A1"	"E9PAW1; hsa:10291; Q15459"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"0"	"3591.2"	"1560.9"	"2923.5"	"2397.3"	"2724.2"	"3271.4"	"2383.7"	"3059.7"	"2360.0"	"3763.3"	"6515.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62316"	"Small nuclear ribonucleoprotein Sm D2 OS=Homo sapiens OX=9606 GN=SNRPD2 PE=1 SV=1"	"0.000"	""	"65"	"12"	"60"	"12"	"118"	"13.5"	"9.91"	"12639.88"	"111.18"	"11"	"11"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf01423"	"6633"	"ENSG00000125743"	"SNRPD2"	"A8K797; hsa:6633; J3KPM5; P43330; P62316"	"mRNA Splicing - Major Pathway; SARS-CoV-2 modulates host translation machinery; snRNP Assembly; mRNA Splicing - Minor Pathway"	"mRNA processing"	"5"	"0"	"4345.3"	"1776.7"	"3162.3"	"2918.5"	"3337.1"	"3574.9"	"2582.6"	"3379.8"	"2596.1"	"4064.3"	"6218.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00571"	"ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3"	"0.000"	""	"42"	"31"	"70"	"30"	"662"	"73.2"	"7.18"	"13109.55"	"109.19"	"28"	"25"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;translation activity;nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"1654"	"ENSG00000215301"	"DDX3X"	"A8K538; B4E3E8; hsa:1654; O00571; O15536"	"Neutrophil degranulation"	"Novel intracellular components of RIG-I-like receptor pathway; Hepatitis B infection"	"3"	"1"	"5119.6"	"1770.6"	"4550.0"	"3525.8"	"4009.6"	"4729.5"	"3259.6"	"4565.8"	"3506.2"	"6742.4"	"9867.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55072"	"Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4"	"0.000"	""	"39"	"28"	"56"	"28"	"806"	"89.3"	"5.26"	"11248.46"	"108.97"	"24"	"25"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"non-structural extracellular;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00004, Pf02359, Pf02933, Pf09336, Pf17862"	"7415"	"ENSG00000165280"	"VCP"	"B2R5T8; hsa:7415; P55072; Q0V924; Q2TAI5; Q969G7; Q9UCD5"	"Neddylation; Aggrephagy; Neutrophil degranulation; HSF1 activation; ABC-family proteins mediated transport; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Defective CFTR causes cystic fibrosis; KEAP1-NFE2L2 pathway; E3 ubiquitin ligases ubiquitinate target proteins; Attachment and Entry; Attachment and Entry; Ovarian tumor domain proteases; Josephin domain DUBs; Protein methylation; RHOH GTPase cycle; Translesion Synthesis by POLH; N-glycan trimming in the ER and Calnexin/Calreticulin cycle"	"Alstrom syndrome; Clock-controlled autophagy in bone metabolism"	"20"	"0"	"3573.8"	"1671.5"	"3376.1"	"3643.3"	"3374.5"	"4261.2"	"3661.4"	"4718.4"	"4003.5"	"6964.4"	"11694.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15393"	"Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4"	"0.000"	""	"22"	"25"	"63"	"24"	"1217"	"135.5"	"5.26"	"11235.34"	"108.48"	"23"	"23"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03178, Pf10433"	"23450"	"ENSG00000189091"	"SF3B3"	"hsa:23450; Q15393; Q6NTI8; Q96GC0; Q9BPY2; Q9UFX7; Q9UJ29"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"mRNA processing"	"3"	"1"	"5016.3"	"1860.0"	"4226.3"	"3950.9"	"3973.7"	"5080.6"	"3921.0"	"4514.3"	"3740.4"	"6479.4"	"10759.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43390"	"Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1"	"0.000"	""	"41"	"23"	"58"	"16"	"633"	"70.9"	"8.13"	"9441.58"	"107.04"	"21"	"23"	"RNA metabolism OR transcription;other metabolic processes"	"ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf18360"	"10236"	"ENSG00000125944; ENSG00000282958"	"HNRNPR"	"hsa:10236; O43390; Q2L7G6; Q5TEH1; Q9BV64; S4R3J4"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"mRNA processing"	"3"	"8"	"5254.5"	"1612.8"	"3121.0"	"2679.1"	"3183.4"	"3439.5"	"2747.9"	"3655.4"	"3313.4"	"5165.1"	"7776.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23246"	"Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2"	"0.000"	""	"26"	"21"	"65"	"20"	"707"	"76.1"	"9.44"	"12686.02"	"106.43"	"21"	"19"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08075"	"6421"	"ENSG00000116560"	"SFPQ"	"hsa:6421; P23246; P30808; Q5SZ71"	"Suppression of apoptosis; PTK6 Regulates Proteins Involved in RNA Processing"	"mRNA processing; Type 2 papillary renal cell carcinoma"	"4"	"1"	"5863.0"	"2573.0"	"5078.5"	"4271.7"	"4941.8"	"5823.0"	"4130.3"	"5378.0"	"4220.7"	"7483.2"	"10604.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P20042"	"Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2 PE=1 SV=2"	"0.000"	""	"50"	"19"	"44"	"19"	"333"	"38.4"	"5.80"	"6668.48"	"106.39"	"11"	"17"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01873"	"8894"	"ENSG00000125977"	"EIF2S2"	"hsa:8894; P20042; Q9BVU0; Q9UJE4"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; ABC-family proteins mediated transport; Response of EIF2AK1 (HRI) to heme deficiency; PERK regulates gene expression; Recycling of eIF2:GDP; Response of EIF2AK4 (GCN2) to amino acid deficiency"	"Translation factors; Brain-derived neurotrophic factor (BDNF) signaling pathway; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell; Primary ovarian insufficiency"	"14"	"0"	"779.5"	"341.7"	"684.3"	"572.2"	"692.7"	"792.3"	"632.8"	"1056.8"	"1442.8"	"14015.9"	"23830.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49407"	"Beta-arrestin-1 OS=Homo sapiens OX=9606 GN=ARRB1 PE=1 SV=2"	"0.000"	""	"45"	"21"	"53"	"17"	"418"	"47.0"	"6.20"	"10002.49"	"105.29"	"18"	"20"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00339, Pf02752"	"408"	"ENSG00000137486"	"ARRB1"	"B6V9G8; hsa:408; O75625; O75630; P49407; Q2PP20; Q9BTK8"	"Ub-specific processing proteases; Activation of SMO; Activated NOTCH1 Transmits Signal to the Nucleus; G alpha (s) signalling events; Lysosome Vesicle Biogenesis; Golgi Associated Vesicle Biogenesis; Signaling by BRAF and RAF1 fusions; Thrombin signalling through proteinase activated receptors (PARs); Cargo recognition for clathrin-mediated endocytosis; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants"	"Corticotropin-releasing hormone signaling pathway; Myometrial relaxation and contraction pathways; MAPK signaling pathway; Chemokine signaling pathway; Hedgehog signaling pathway; Gastrin signaling pathway; Kisspeptin/kisspeptin receptor system in the ovary; GPR143 in melanocytes and retinal pigment epithelium cells; Calcium regulation in cardiac cells"	"25"	"0"	"360.8"	"185.8"	"404.4"	"488.7"	"504.2"	"936.2"	"1272.1"	"2660.5"	"3145.0"	"5729.1"	"5600.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75533"	"Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3"	"0.000"	""	"20"	"23"	"62"	"23"	"1304"	"145.7"	"7.09"	"11419.96"	"103.58"	"21"	"20"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf08920"	"23451"	"ENSG00000115524"	"SF3B1"	"E9PCH3; hsa:23451; O75533"	"mRNA Splicing - Major Pathway; B-WICH complex positively regulates rRNA expression; mRNA Splicing - Minor Pathway"	"mRNA processing; 10q11.21q11.23 copy number variation syndrome"	"5"	"0"	"3110.2"	"1195.9"	"2545.3"	"2390.4"	"2532.7"	"2837.6"	"2036.0"	"2598.6"	"2036.4"	"3636.7"	"7295.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15029"	"116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1"	"0.000"	""	"33"	"25"	"48"	"24"	"972"	"109.4"	"5.00"	"9249.13"	"103.15"	"20"	"25"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf00679, Pf03144, Pf03764, Pf14492, Pf16004"	"9343"	"ENSG00000108883"	"EFTUD2"	"B4DK30; B4DMC0; D3DX58; hsa:9343; K7EJ81; Q15029; Q9BUR0"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"mRNA processing; Ciliary landscape"	"4"	"1"	"3574.4"	"1424.5"	"2633.9"	"2270.4"	"2432.7"	"2928.1"	"2174.5"	"2798.1"	"2315.0"	"4366.0"	"9323.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q10567"	"AP-1 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP1B1 PE=1 SV=2"	"0.000"	""	"29"	"28"	"69"	"12"	"949"	"104.6"	"5.06"	"13105.93"	"101.02"	"27"	"25"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"816.4"	"313.1"	"672.2"	"577.5"	"682.1"	"806.5"	"890.5"	"2663.8"	"3047.0"	"5893.9"	"7103.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52597"	"Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3"	"0.000"	""	"49"	"17"	"46"	"14"	"415"	"45.6"	"5.58"	"6201.01"	"100.93"	"13"	"15"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf08080"	"3185"	"ENSG00000169813"	"HNRNPF"	"B3KM84; hsa:3185; P52597; Q5T0N2; Q96AU2"	"mRNA Splicing - Major Pathway; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"MECP2 and associated Rett syndrome"	"5"	"3"	"3081.7"	"1511.2"	"3553.5"	"2795.8"	"2938.5"	"3603.5"	"2447.7"	"3345.7"	"2721.0"	"5091.0"	"7399.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P99999"	"Cytochrome c OS=Homo sapiens OX=9606 GN=CYCS PE=1 SV=2"	"0.000"	""	"64"	"9"	"61"	"9"	"105"	"11.7"	"9.57"	"11935.92"	"100.87"	"9"	"8"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"other membranes;cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf00034"	"54205"	"ENSG00000172115"	"CYCS"	"A4D166; B2R4I1; hsa:54205; P00001; P99999; Q6NUR2; Q6NX69; Q96BV4"	"Respiratory electron transport; Detoxification of Reactive Oxygen Species; Transcriptional activation of mitochondrial biogenesis; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1; Activation of caspases through apoptosome-mediated cleavage; SMAC (DIABLO) binds to IAPs ; SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes ; Regulation of the apoptosome activity; Release of apoptotic factors from the mitochondria; Pyroptosis"	"miRNA regulation of DNA damage response; Apoptosis modulation and signaling; Alzheimer's disease and miRNA effects; AGE/RAGE pathway; Parkinson's disease pathway; Nanomaterial induced apoptosis; Apoptosis; Fas ligand pathway and stress induction of heat shock proteins; Apoptosis modulation by HSP70; VEGFA-VEGFR2 signaling; Oxidative damage response; NO/cGMP/PKG mediated neuroprotection; Chromosomal and microsatellite instability in colorectal cancer ; Non-small cell lung cancer; Acute viral myocarditis; Nonalcoholic fatty liver disease; Measles virus infection; Small cell lung cancer; Hepatitis B infection; IL-18 signaling pathway; Pleural mesothelioma; Complement system in neuronal development and plasticity; Alzheimer's disease; DNA damage response"	"36"	"0"	"3880.4"	"2337.9"	"3689.8"	"3435.5"	"3739.8"	"4140.8"	"3667.1"	"4454.4"	"3619.2"	"5973.4"	"4746.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P38646"	"Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2"	"0.000"	""	"39"	"22"	"52"	"22"	"679"	"73.6"	"6.16"	"9197.39"	"99.88"	"19"	"21"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00012"	"3313"	"ENSG00000113013"	"HSPA9"	"B2RCM1; hsa:3313; P30036; P31932; P38646; Q1HB43; Q53H23; Q6GU03; Q9BWB7; Q9UC56"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Mitochondrial protein import; Regulation of HSF1-mediated heat shock response; Cristae formation"	"Parkin-ubiquitin proteasomal system pathway; Iron-sulfur cluster biogenesis"	"6"	"0"	"4329.4"	"2044.0"	"3785.2"	"3536.7"	"3757.8"	"4386.7"	"3211.9"	"4334.4"	"3223.5"	"6187.8"	"11920.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09651"	"Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5"	"0.000"	""	"47"	"17"	"57"	"15"	"372"	"38.7"	"9.13"	"9980.03"	"99.71"	"14"	"14"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf11627"	"3178"	"ENSG00000135486"	"HNRNPA1"	"A8K4Z8; hsa:3178; P09651; Q3MIB7; Q6PJZ7"	"mRNA Splicing - Major Pathway; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA; SARS-CoV-1-host interactions; SARS-CoV-1 modulates host translation machinery"	"mRNA processing"	"6"	"0"	"4052.8"	"1697.7"	"2607.4"	"2114.9"	"2379.9"	"2682.1"	"2274.2"	"2815.4"	"2684.7"	"4157.6"	"5371.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P04075"	"Fructose-bisphosphate aldolase A OS=Homo sapiens OX=9606 GN=ALDOA PE=1 SV=2"	"0.000"	""	"54"	"19"	"55"	"19"	"364"	"39.4"	"8.09"	"10470.52"	"99.04"	"18"	"17"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00274"	"226"	"ENSG00000149925"	"ALDOA"	"B4DXI7; hsa:226; P04075; Q6FH76; Q6FI10; Q96B15; Q9BWD9; Q9UCN2"	"Neutrophil degranulation; Glycolysis; Gluconeogenesis; Platelet degranulation"	"VEGFA-VEGFR2 signaling; Clear cell renal cell carcinoma pathways; Aerobic glycolysis; 16p11.2 proximal deletion syndrome; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders; Sudden infant death syndrome (SIDS) susceptibility pathways"	"11"	"0"	"3156.1"	"1505.4"	"2966.6"	"2752.1"	"2840.7"	"3551.9"	"2828.4"	"3297.6"	"2963.0"	"5149.9"	"8467.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86XP3"	"ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1"	"0.000"	""	"25"	"20"	"50"	"20"	"938"	"102.9"	"7.02"	"9530.69"	"98.52"	"18"	"17"	"other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"11325"	"ENSG00000198231"	"DDX42"	"A6NML1; A8KA43; hsa:11325; O75619; Q68G51; Q86XP3; Q96BK1; Q96HR7; Q9Y3V8"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	""	"2"	"0"	"2580.1"	"1414.8"	"2451.8"	"2093.6"	"2354.9"	"2773.6"	"2117.2"	"2694.7"	"2195.4"	"3462.0"	"4790.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5JSL3"	"Dedicator of cytokinesis protein 11 OS=Homo sapiens OX=9606 GN=DOCK11 PE=1 SV=2"	"0.000"	""	"15"	"26"	"69"	"25"	"2073"	"237.5"	"7.74"	"11641.53"	"97.86"	"24"	"24"	"signal transduction;other biological processes"	"cytosol"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf06920, Pf11878, Pf14429, Pf20421, Pf20422"	"139818"	"ENSG00000147251"	"DOCK11"	"A6NMF0; hsa:139818; Q5JSL3; Q66M66; Q6ZUJ5; Q86VU8; Q96MN3"	"CDC42 GTPase cycle; RAC1 GTPase cycle; Factors involved in megakaryocyte development and platelet production"	""	"3"	"1"	"805.6"	"357.9"	"808.6"	"694.2"	"770.8"	"1214.9"	"1832.5"	"4900.3"	"4743.0"	"7716.7"	"6150.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99459"	"Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2"	"0.000"	""	"27"	"16"	"40"	"16"	"802"	"92.2"	"8.18"	"5688.83"	"97.68"	"13"	"16"	"cell cycle OR cell proliferation;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf11831, Pf13921"	"988"	"ENSG00000096401"	"CDC5L"	"hsa:988; Q76N46; Q99459; Q99974"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"2011.6"	"789.1"	"1463.6"	"1245.4"	"1428.2"	"1556.9"	"1249.5"	"1541.4"	"1382.0"	"6833.0"	"20289.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UMS4"	"Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1"	"0.000"	""	"40"	"13"	"39"	"13"	"504"	"55.1"	"6.61"	"5004.27"	"97.21"	"8"	"13"	"cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00400, Pf04564, Pf08606"	"27339"	"ENSG00000110107"	"PRPF19"	"hsa:27339; Q9UMS4"	"mRNA Splicing - Major Pathway; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of TC-NER Pre-Incision Complex"	""	"5"	"0"	"1206.8"	"534.1"	"921.3"	"814.6"	"895.2"	"1050.3"	"828.8"	"1028.3"	"986.0"	"6005.7"	"18459.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94832"	"Unconventional myosin-Id OS=Homo sapiens OX=9606 GN=MYO1D PE=1 SV=2"	"0.000"	""	"28"	"24"	"51"	"24"	"1006"	"116.1"	"9.39"	"8349.66"	"96.13"	"19"	"22"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00063, Pf00612, Pf06017"	"4642"	"ENSG00000176658"	"MYO1D"	"A6H8V3; hsa:4642; O94832; Q8NHP9"	""	""	"0"	"0"	"918.1"	"409.1"	"839.5"	"716.3"	"906.2"	"969.0"	"795.0"	"1624.4"	"2455.4"	"9025.7"	"12959.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26639"	"Threonine--tRNA ligase 1, cytoplasmic OS=Homo sapiens OX=9606 GN=TARS1 PE=1 SV=3"	"0.000"	""	"38"	"22"	"40"	"22"	"723"	"83.4"	"6.67"	"4725.00"	"95.98"	"12"	"20"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol"	"nucleic acid binding activity;other molecular function"	"Pf00587, Pf02824, Pf03129, Pf07973"	"6897"	"ENSG00000113407"	"TARS1"	"A8K8I1; B4DEG8; hsa:6897; P26639; Q96FP5; Q9BWA6"	"Cytosolic tRNA aminoacylation"	""	"1"	"0"	"644.2"	"255.4"	"507.6"	"454.1"	"510.7"	"565.3"	"491.4"	"596.6"	"603.4"	"7030.1"	"20495.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15020"	"Spectrin beta chain, non-erythrocytic 2 OS=Homo sapiens OX=9606 GN=SPTBN2 PE=1 SV=3"	"0.000"	""	"13"	"24"	"45"	"19"	"2390"	"271.2"	"6.11"	"7740.43"	"94.88"	"18"	"22"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00435, Pf15410"	"6712"	"ENSG00000173898"	"SPTBN2"	"hsa:6712; O14872; O14873; O15020"	"MHC class II antigen presentation; COPI-mediated anterograde transport; RAF/MAP kinase cascade; NCAM signaling for neurite out-growth; Interaction between L1 and Ankyrins"	""	"5"	"0"	"1136.4"	"459.3"	"904.4"	"792.7"	"923.2"	"984.7"	"811.6"	"1265.5"	"1419.0"	"5434.9"	"10764.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P17844"	"Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1"	"0.000"	""	"37"	"26"	"64"	"17"	"614"	"69.1"	"8.92"	"10145.41"	"94.49"	"23"	"24"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf08061"	"1655"	"ENSG00000108654"	"DDX5"	"B4DLW8; B5BU21; D3DU32; E7ETL9; hsa:1655; O75681; P17844; Q53Y61"	"mRNA Splicing - Major Pathway; SUMOylation of transcription cofactors; Estrogen-dependent gene expression; Replication of the SARS-CoV-1 genome; Replication of the SARS-CoV-2 genome"	"Ciliary landscape"	"6"	"0"	"5701.4"	"1420.0"	"3087.4"	"2566.0"	"3060.7"	"3356.2"	"2367.6"	"3279.4"	"2483.7"	"4598.5"	"8251.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07437"	"Tubulin beta chain OS=Homo sapiens OX=9606 GN=TUBB PE=1 SV=2"	"0.000"	""	"38"	"13"	"43"	"2"	"444"	"49.6"	"4.89"	"7856.81"	"92.79"	"12"	"13"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;other biological processes"	"non-structural extracellular;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00091, Pf03953"	"203068"	"ENSG00000183311; ENSG00000196230; ENSG00000224156; ENSG00000227739; ENSG00000229684; ENSG00000232421; ENSG00000232575; ENSG00000235067"	"TUBB"	"hsa:203068; P05218; P07437; Q8WUC1; Q9CY33"	"Neutrophil degranulation; Potential therapeutics for SARS; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"Alzheimer's disease and miRNA effects; Pathogenic Escherichia coli infection; Parkin-ubiquitin proteasomal system pathway; Opioid receptor pathways; Alzheimer's disease"	"14"	"13"	"1718.4"	"732.2"	"1447.1"	"1243.5"	"1386.6"	"1589.4"	"1255.0"	"1585.9"	"1380.9"	"2523.0"	"4487.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62258"	"14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1"	"0.000"	""	"64"	"16"	"55"	"14"	"255"	"29.2"	"4.74"	"11339.12"	"92.08"	"15"	"15"	"stress response;transport;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00244"	"7531"	"ENSG00000108953; ENSG00000274474"	"YWHAE"	"B3KY71; D3DTH5; hsa:7531; P29360; P42655; P62258; Q4VJB6; Q53XZ5; Q63631; Q7M4R4"	"Regulation of HSF1-mediated heat shock response; TP53 Regulates Metabolic Genes; HSF1 activation; RAB GEFs exchange GTP for GDP on RABs; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Activation of BAD and translocation to mitochondria ; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Signaling by Hippo; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models; NADE modulates death signalling"	"Cell cycle; Myometrial relaxation and contraction pathways; VEGFA-VEGFR2 signaling; Calcium regulation in cardiac cells; 17p13.3 (YWHAE) copy number variation; Sudden infant death syndrome (SIDS) susceptibility pathways"	"26"	"4"	"4075.3"	"2003.9"	"4038.3"	"3373.4"	"3911.8"	"5070.5"	"4026.7"	"5113.2"	"3898.3"	"6577.6"	"11042.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19338"	"Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3"	"0.000"	""	"30"	"22"	"57"	"22"	"710"	"76.6"	"4.70"	"9247.12"	"91.77"	"19"	"19"	"developmental processes;other biological processes"	"plasma membrane;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"4691"	"ENSG00000115053"	"NCL"	"hsa:4691; P19338; Q53SK1; Q8NB06; Q9UCF0; Q9UDG1"	"Major pathway of rRNA processing in the nucleolus and cytosol"	"Pathogenic Escherichia coli infection; VEGFA-VEGFR2 signaling"	"3"	"0"	"6243.4"	"2900.3"	"5433.2"	"4836.9"	"5164.3"	"6326.8"	"5203.1"	"6790.1"	"4975.3"	"7996.9"	"12166.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P41091"	"Eukaryotic translation initiation factor 2 subunit 3 OS=Homo sapiens OX=9606 GN=EIF2S3 PE=1 SV=3"	"0.000"	""	"43"	"15"	"40"	"15"	"472"	"51.1"	"8.40"	"4924.27"	"91.39"	"9"	"15"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03144, Pf09173"	"1968"	"ENSG00000130741"	"EIF2S3"	"A0A024RBY4; A8K2Y2; B2R5N2; B5BTZ4; hsa:1968; P41091; Q53HK3"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; ABC-family proteins mediated transport; Response of EIF2AK1 (HRI) to heme deficiency; PERK regulates gene expression; Recycling of eIF2:GDP; Response of EIF2AK4 (GCN2) to amino acid deficiency"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"12"	"0"	"1310.5"	"391.5"	"925.3"	"753.9"	"994.3"	"1135.3"	"899.7"	"1356.4"	"1435.3"	"9875.0"	"24689.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43290"	"U4/U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1"	"0.000"	""	"36"	"25"	"47"	"25"	"800"	"90.2"	"6.13"	"8607.73"	"90.48"	"22"	"23"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	""	"Pf03343, Pf19252"	"9092"	"ENSG00000175467"	"SART1"	"A6NDN1; hsa:9092; O43290; Q53GB5"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"2495.6"	"968.7"	"2047.7"	"1724.9"	"1897.1"	"2217.5"	"1543.7"	"2206.9"	"1751.2"	"3949.3"	"7087.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P68104"	"Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1"	"0.000"	""	"41"	"15"	"48"	"7"	"462"	"50.1"	"9.01"	"6622.87"	"89.04"	"12"	"13"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;translational apparatus;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03143, Pf03144"	"1915"	"ENSG00000156508"	"EEF1A1"	"hsa:1915; P04719; P04720; P68104; Q6IQ15"	"Chaperone Mediated Autophagy; Peptide chain elongation; SARS-CoV-1 modulates host translation machinery; Neutrophil degranulation; Protein methylation; HSF1 activation"	"Translation factors; Fragile X syndrome; 2q37 copy number variation syndrome"	"10"	"11"	"5178.1"	"2452.2"	"4215.2"	"3363.3"	"3710.1"	"4370.4"	"3444.0"	"4599.1"	"4021.6"	"7973.0"	"14397.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P60891"	"Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2"	"0.000"	""	"50"	"14"	"46"	"6"	"318"	"34.8"	"6.98"	"8335.14"	"87.54"	"13"	"14"	"other metabolic processes;developmental processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf13793, Pf14572"	"5631"	"ENSG00000147224"	"PRPS1"	"B1ALA8; B2R6T7; B4DNL6; D3DUX6; hsa:5631; P09329; P60891"	"5-Phosphoribose 1-diphosphate biosynthesis"	""	"1"	"10"	"1533.8"	"993.0"	"1458.1"	"1341.7"	"1399.9"	"1731.3"	"1391.4"	"1781.4"	"2135.1"	"4587.3"	"8461.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15149"	"Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3"	"0.000"	""	"7"	"27"	"48"	"26"	"4684"	"531.5"	"5.96"	"7873.31"	"87.34"	"21"	"25"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00681, Pf03501, Pf17902, Pf18373"	"5339"	"ENSG00000178209"	"PLEC"	"hsa:5339; Q15148; Q15149; Q16640; Q6S376; Q6S377; Q6S378; Q6S379; Q6S380; Q6S381; Q6S382; Q6S383"	"Assembly of collagen fibrils and other multimeric structures; Caspase-mediated cleavage of cytoskeletal proteins; Type I hemidesmosome assembly"	"Envelope proteins and their potential roles in EDMD physiopathology"	"4"	"2"	"2550.5"	"971.7"	"1905.7"	"1626.8"	"1983.2"	"2088.2"	"1584.9"	"2217.0"	"1684.2"	"3427.4"	"5688.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15233"	"Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4"	"0.000"	""	"35"	"18"	"51"	"16"	"471"	"54.2"	"8.95"	"10723.78"	"87.31"	"17"	"17"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08075"	"4841"	"ENSG00000147140"	"NONO"	"B7Z4C2; D3DVV4; F5GYZ3; hsa:4841; O00201; P30807; Q12786; Q15233; Q9BQC5"	""	"mRNA processing"	"1"	"1"	"5303.0"	"2532.7"	"5013.7"	"4396.1"	"4754.5"	"5410.5"	"3785.9"	"4754.2"	"3574.5"	"6313.4"	"9775.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60506"	"Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2"	"0.000"	""	"36"	"19"	"46"	"12"	"623"	"69.6"	"8.59"	"7302.20"	"86.42"	"15"	"19"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf18360"	"10492"	"ENSG00000135316"	"SYNCRIP"	"E1P501; E1P502; hsa:10492; O60506; Q53H05; Q5TCG2; Q5TCG3; Q8IW78; Q8N599; Q96LC1; Q96LC2; Q9Y583"	""	""	"0"	"0"	"2346.9"	"747.1"	"1425.1"	"1142.9"	"1400.5"	"1565.0"	"1285.9"	"1616.5"	"1494.2"	"2339.0"	"3981.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P68371"	"Tubulin beta-4B chain OS=Homo sapiens OX=9606 GN=TUBB4B PE=1 SV=1"	"0.000"	""	"35"	"12"	"39"	"1"	"445"	"49.8"	"4.89"	"7031.13"	"85.75"	"11"	"12"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response"	"non-structural extracellular;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00091, Pf03953"	"10383"	"ENSG00000188229"	"TUBB4B"	"A2BFA2; hsa:10383; P05217; P68371"	"MHC class II antigen presentation; COPI-mediated anterograde transport; HCMV Early Events; Neutrophil degranulation; Formation of tubulin folding intermediates by CCT/TriC; Prefoldin mediated transfer of substrate  to CCT/TriC; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-independent Golgi-to-ER retrograde traffic; Intraflagellar transport; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Recruitment of NuMA to mitotic centrosomes; RHO GTPases Activate Formins; Aggrephagy; EML4 and NUDC in mitotic spindle formation; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Recycling pathway of L1; Translocation of SLC2A4 (GLUT4) to the plasma membrane; RHO GTPases activate IQGAPs; COPI-dependent Golgi-to-ER retrograde traffic; The role of GTSE1 in G2/M progression after G2 checkpoint; Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane; Gap junction assembly; Post-chaperonin tubulin folding pathway; Carboxyterminal post-translational modifications of tubulin; Assembly and cell surface presentation of NMDA receptors; Activation of AMPK downstream of NMDARs; Sealing of the nuclear envelope (NE) by ESCRT-III; Kinesins; Hedgehog 'off' state"	"Alzheimer's disease and miRNA effects; Pathogenic Escherichia coli infection; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"41"	"0"	"98.4"	"33.9"	"79.0"	"52.4"	"66.0"	"88.2"	"63.9"	"78.6"	"63.9"	"98.4"	"170.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13639"	"Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4"	"0.000"	""	"31"	"23"	"50"	"22"	"858"	"95.3"	"6.83"	"9848.88"	"85.04"	"22"	"20"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00009, Pf00679, Pf03144, Pf03764, Pf14492"	"1938"	"ENSG00000167658"	"EEF2"	"A0A384N6H1; B2RMP5; D6W618; hsa:1938; P13639; Q58J86"	"Neutrophil degranulation; Protein methylation; Uptake and function of diphtheria toxin; Peptide chain elongation; Synthesis of diphthamide-EEF2"	"Translation factors; AMP-activated protein kinase signaling; Brain-derived neurotrophic factor (BDNF) signaling pathway; IL-18 signaling pathway"	"9"	"0"	"2041.2"	"874.9"	"1764.3"	"1592.2"	"1736.5"	"2117.7"	"1607.2"	"1866.7"	"1491.6"	"2840.3"	"8225.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P12956"	"X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2"	"0.000"	""	"28"	"17"	"51"	"17"	"609"	"69.8"	"6.64"	"11087.23"	"84.86"	"16"	"13"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02037, Pf02735, Pf03730, Pf03731"	"2547"	"ENSG00000196419"	"XRCC6"	"B1AHC8; hsa:2547; P12956; Q6FG89; Q9UCQ2; Q9UCQ3"	"Neutrophil degranulation; Cytosolic sensors of pathogen-associated DNA ; Nonhomologous End-Joining (NHEJ); 2-LTR circle formation; IRF3-mediated induction of type I IFN"	"Non-homologous end joining; DNA repair pathways, full network; Primary ovarian insufficiency"	"8"	"0"	"2641.9"	"1220.3"	"2389.0"	"2157.4"	"2285.2"	"2782.3"	"2001.6"	"2394.7"	"1764.9"	"3186.6"	"5239.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08865"	"40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4"	"0.000"	""	"58"	"15"	"32"	"15"	"295"	"32.8"	"4.87"	"4325.03"	"84.83"	"10"	"15"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;translational apparatus;nucleus;other cell component"	"translation activity;other molecular function"	"Pf00318, Pf16122"	"3921"	"ENSG00000168028"	"RPSA"	"hsa:3921; P08865; P11085; P12030; Q16471; Q6IPD1; Q6IPD2; Q6NSD1; Q6NXQ8; Q86VC0"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"1756.4"	"804.2"	"1655.4"	"1412.4"	"1409.6"	"1870.2"	"1409.6"	"1835.1"	"1405.2"	"2060.2"	"2901.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99729"	"Heterogeneous nuclear ribonucleoprotein A/B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2"	"0.000"	""	"29"	"13"	"55"	"11"	"332"	"36.2"	"8.21"	"9002.73"	"82.90"	"12"	"11"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08143"	"3182"	"ENSG00000197451"	"HNRNPAB"	"B3KNN5; D3DWP7; hsa:3182; Q04150; Q8N7U3; Q99729; Q9BQ99"	""	"Pre-implantation embryo; mRNA processing"	"2"	"0"	"4970.7"	"1544.0"	"2989.6"	"2476.0"	"2721.6"	"3131.4"	"2463.4"	"3220.8"	"2806.2"	"3822.3"	"5176.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5JRX3"	"Presequence protease, mitochondrial OS=Homo sapiens OX=9606 GN=PITRM1 PE=1 SV=3"	"0.000"	""	"24"	"18"	"28"	"18"	"1037"	"117.3"	"6.92"	"3042.97"	"82.23"	"7"	"18"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport"	"mitochondrion"	"enzyme regulator activity;other molecular function"	"Pf00675, Pf05193, Pf08367"	"10531"	"ENSG00000107959"	"PITRM1"	"B3KMJ6; B4E0J8; C9JSL2; E7ES23; hsa:10531; O95204; Q2M2G6; Q4VBR1; Q5JRW7; Q5JRX3; Q7L5Z7; Q9BSI6; Q9BVJ5; Q9UPP8"	"Mitochondrial protein import"	""	"1"	"0"	"547.1"	"222.6"	"420.7"	"367.1"	"434.5"	"495.8"	"387.8"	"533.8"	"577.8"	"4109.2"	"15736.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08238"	"Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4"	"0.000"	""	"40"	"26"	"47"	"13"	"724"	"83.2"	"5.03"	"7248.07"	"82.17"	"21"	"24"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00183, Pf02518"	"3326"	"ENSG00000096384"	"HSP90AB1"	"B2R5P0; hsa:3326; P08238; Q5T9W7; Q9NQW0; Q9NTK6"	"The role of GTSE1 in G2/M progression after G2 checkpoint; Neutrophil degranulation; Potential therapeutics for SARS; Regulation of actin dynamics for phagocytic cup formation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Aryl hydrocarbon receptor signalling; Estrogen-dependent gene expression; Sema3A PAK dependent Axon repulsion; DDX58/IFIH1-mediated induction of interferon-alpha/beta; The NLRP3 inflammasome; Purinergic signaling in leishmaniasis infection; RHOBTB2 GTPase cycle; Chaperone Mediated Autophagy; HSF1 activation; Attenuation phase; Uptake and function of diphtheria toxin"	"Nuclear receptors meta-pathway; NRF2 pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway"	"23"	"13"	"3808.4"	"1460.6"	"2868.2"	"2338.9"	"2932.2"	"3099.8"	"2544.4"	"3215.7"	"2778.4"	"4282.6"	"7365.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P39748"	"Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1 PE=1 SV=1"	"0.000"	""	"41"	"11"	"29"	"11"	"380"	"42.6"	"8.62"	"4360.14"	"81.76"	"6"	"11"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00752, Pf00867"	"2237"	"ENSG00000168496"	"FEN1"	"hsa:2237; P39748"	"HDR through MMEJ (alt-NHEJ); Early Phase of HIV Life Cycle; POLB-Dependent Long Patch Base Excision Repair; PCNA-Dependent Long Patch Base Excision Repair; Removal of the Flap Intermediate; Removal of the Flap Intermediate from the C-strand"	"Base excision repair; DNA repair pathways, full network"	"8"	"0"	"666.9"	"297.3"	"637.7"	"501.8"	"662.5"	"786.7"	"594.2"	"1062.0"	"835.5"	"3761.9"	"13646.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92804"	"TATA-binding protein-associated factor 2N OS=Homo sapiens OX=9606 GN=TAF15 PE=1 SV=1"	"0.000"	""	"26"	"11"	"30"	"8"	"592"	"61.8"	"8.02"	"3256.61"	"81.36"	"7"	"11"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00641"	"8148"	"ENSG00000270647; ENSG00000276833"	"TAF15"	"B2R837; hsa:8148; Q86X94; Q92751; Q92804"	"Regulation of TP53 Activity through Phosphorylation; RNA Polymerase II Pre-transcription Events; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation"	"17q12 copy number variation syndrome"	"10"	"0"	"948.6"	"339.8"	"665.3"	"579.8"	"592.0"	"746.5"	"549.5"	"645.8"	"513.2"	"806.3"	"1163.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q07955"	"Serine/arginine-rich splicing factor 1 OS=Homo sapiens OX=9606 GN=SRSF1 PE=1 SV=2"	"0.000"	""	"49"	"15"	"43"	"15"	"248"	"27.7"	"10.36"	"6269.13"	"79.36"	"11"	"14"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6426"	"ENSG00000136450"	"SRSF1"	"B2R6Z7; D3DTZ3; hsa:6426; Q07955; Q13809"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Minor Pathway"	"mRNA processing"	"7"	"0"	"4596.0"	"1793.9"	"2913.8"	"2505.1"	"2801.2"	"3057.4"	"2619.5"	"3272.4"	"2990.8"	"4735.4"	"4581.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14152"	"Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1"	"0.000"	""	"20"	"26"	"51"	"26"	"1382"	"166.5"	"6.79"	"9514.26"	"79.36"	"24"	"23"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;translational apparatus;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf01399"	"8661"	"ENSG00000107581"	"EIF3A"	"B1AMV5; B4DYS1; F5H335; hsa:8661; O00653; Q14152; Q15778"	"Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"8"	"0"	"3758.8"	"1828.9"	"3285.3"	"3071.8"	"3180.6"	"3765.1"	"2725.5"	"3390.2"	"2395.2"	"3838.5"	"7212.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P60709"	"Actin, cytoplasmic 1 OS=Homo sapiens OX=9606 GN=ACTB PE=1 SV=1"	"0.000"	""	"33"	"12"	"41"	"3"	"375"	"41.7"	"5.48"	"8181.92"	"78.59"	"11"	"11"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00022"	"60"	"ENSG00000075624"	"ACTB"	"hsa:60; P02570; P60709; P70514; P99021; Q11211; Q64316; Q75MN2; Q96B34; Q96HG5"	"RHO GTPases activate IQGAPs; Translocation of SLC2A4 (GLUT4) to the plasma membrane; UCH proteinases; Clathrin-mediated endocytosis; DNA Damage Recognition in GG-NER; Signaling by BRAF and RAF1 fusions; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; Recycling pathway of L1; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; RHO GTPases Activate WASPs and WAVEs; RHO GTPases Activate Formins; RHOF GTPase cycle; B-WICH complex positively regulates rRNA expression; EPHB-mediated forward signaling; VEGFA-VEGFR2 Pathway; Factors involved in megakaryocyte development and platelet production; EPH-ephrin mediated repulsion of cells; HATs acetylate histones; Interaction between L1 and Ankyrins; Prefoldin mediated transfer of substrate  to CCT/TriC; Adherens junctions interactions; Formation of annular gap junctions; Folding of actin by CCT/TriC; Cell-extracellular matrix interactions"	"Arrhythmogenic right ventricular cardiomyopathy; Pathogenic Escherichia coli infection; Common pathways underlying drug addiction; Myometrial relaxation and contraction pathways; Focal adhesion; Fas ligand pathway and stress induction of heat shock proteins; Ebola virus infection in host; Acute viral myocarditis; Thermogenesis; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Overlap between signal transduction pathways contributing to LMNA laminopathies; Pleural mesothelioma; Regulation of actin cytoskeleton; Network map of SARS-CoV-2 signaling pathway"	"47"	"14"	"3829.0"	"1597.8"	"2206.3"	"1565.3"	"2347.0"	"2150.7"	"2214.6"	"2495.4"	"3046.0"	"4431.4"	"7875.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63104"	"14-3-3 protein zeta/delta OS=Homo sapiens OX=9606 GN=YWHAZ PE=1 SV=1"	"0.000"	""	"62"	"14"	"39"	"12"	"245"	"27.7"	"4.79"	"7272.27"	"77.79"	"12"	"14"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00244"	"7534"	"ENSG00000164924"	"YWHAZ"	"A8K1N0; B7Z465; hsa:7534; P29213; P29312; P63104; Q32P43; Q5XJ08; Q6GPI2; Q6IN74; Q6NUR9; Q6P3U9; Q86V33"	"RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Regulation of localization of FOXO transcription factors; Negative regulation of NOTCH4 signaling; Deactivation of the beta-catenin transactivating complex; Interleukin-3, Interleukin-5 and GM-CSF signaling; TP53 Regulates Metabolic Genes; NOTCH4 Activation and Transmission of Signal to the Nucleus; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; Rap1 signalling; KSRP (KHSRP) binds and destabilizes mRNA; GP1b-IX-V activation signalling; Activation of BAD and translocation to mitochondria"	"Cell cycle; Prolactin signaling pathway; Pathogenic Escherichia coli infection; Myometrial relaxation and contraction pathways; Hepatitis B infection; GDNF signaling; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"23"	"0"	"2011.4"	"897.3"	"2106.3"	"1948.3"	"2042.3"	"2520.0"	"2030.0"	"2519.2"	"1702.3"	"3046.0"	"5009.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23396"	"40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2"	"0.000"	""	"64"	"15"	"42"	"15"	"243"	"26.7"	"9.66"	"7308.33"	"77.34"	"14"	"14"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;translational apparatus;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00189, Pf07650"	"6188"	"ENSG00000149273"	"RPS3"	"B2R7N5; hsa:6188; J3KN86; P23396; Q498B5; Q8NI95"	"GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"3173.2"	"1321.3"	"2901.5"	"2724.3"	"2872.7"	"3387.7"	"2392.8"	"2922.0"	"2192.0"	"3873.2"	"7236.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HB71"	"Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2"	"0.000"	""	"60"	"12"	"30"	"12"	"228"	"26.2"	"8.25"	"4378.78"	"76.92"	"6"	"12"	"developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf04969, Pf05002, Pf09032"	"27101"	"ENSG00000116161"	"CACYBP"	"B2ZWH2; B3KSF1; hsa:27101; O60666; Q5R370; Q5R371; Q9HB71"	""	"Gastric cancer network 2"	"1"	"0"	"438.1"	"214.6"	"350.3"	"373.0"	"406.3"	"468.6"	"364.0"	"544.5"	"894.1"	"3756.8"	"9188.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26599"	"Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1"	"0.000"	""	"32"	"13"	"51"	"11"	"531"	"57.2"	"9.17"	"10230.03"	"76.60"	"10"	"11"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf11835, Pf13893"	"749887"	"ENSPPYG00000009289; ENSPTRG00000010165"	"PTBP1"	"A0A2J8IKP3; A0A2J8RA51; A0A6D2WFY9; A0A8I5YPF9; K7AXA8"	""	""	"0"	"4"	"3452.2"	"1737.2"	"3146.9"	"2605.6"	"2813.1"	"3423.7"	"2505.3"	"2842.0"	"2381.2"	"3961.1"	"7164.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P40926"	"Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3"	"0.000"	""	"54"	"15"	"43"	"15"	"338"	"35.5"	"8.68"	"7147.95"	"76.59"	"13"	"14"	"other metabolic processes"	"other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf00056, Pf02866"	"4191"	"ENSG00000146701"	"MDH2"	"A8K414; B2RE78; B4DE44; E9PDB2; hsa:4191; O43682; P40926"	"Gluconeogenesis; Citric acid cycle (TCA cycle)"	"Amino acid metabolism; Metabolic reprogramming in colon cancer; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders; TCA cycle (aka Krebs or citric acid cycle)"	"8"	"0"	"2448.5"	"1361.7"	"2414.1"	"2205.8"	"2221.7"	"2676.2"	"2161.1"	"2807.5"	"2415.2"	"4150.5"	"11190.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05455"	"Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2"	"0.000"	""	"44"	"19"	"50"	"19"	"408"	"46.8"	"7.12"	"9578.09"	"76.59"	"18"	"16"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf05383, Pf08777"	"6741"	"ENSG00000138385"	"SSB"	"hsa:6741; P05455; Q15367; Q53XJ4"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Termination"	""	"2"	"0"	"3833.2"	"1811.8"	"3766.1"	"3431.9"	"3688.9"	"4688.6"	"3736.1"	"4793.5"	"3671.4"	"7021.2"	"9702.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y450"	"HBS1-like protein OS=Homo sapiens OX=9606 GN=HBS1L PE=1 SV=1"	"0.000"	""	"35"	"18"	"34"	"18"	"684"	"75.4"	"6.61"	"5978.94"	"76.57"	"14"	"17"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03143, Pf03144, Pf08938"	"10767"	"ENSG00000112339"	"HBS1L"	"B7Z365; hsa:10767; Q4VX89; Q4VX90; Q5T7G3; Q8NDW9; Q9UPW3; Q9Y450"	"mRNA decay by 3' to 5' exoribonuclease"	""	"1"	"0"	"583.4"	"252.7"	"527.0"	"412.1"	"547.9"	"634.4"	"540.6"	"1630.2"	"2673.3"	"8209.8"	"10980.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P34897"	"Serine hydroxymethyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=SHMT2 PE=1 SV=3"	"0.000"	""	"36"	"16"	"41"	"15"	"504"	"56.0"	"8.53"	"6554.43"	"76.32"	"14"	"15"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00464"	"6472"	"ENSG00000182199"	"SHMT2"	"B7Z9F1; E7EQ19; E7EU43; hsa:6472; O00740; P34897; Q8N1A5"	"RHOG GTPase cycle; Metabolism of folate and pterines"	"Glycine metabolism; Vitamin B12 metabolism; Folate metabolism; One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Neuroinflammation and glutamatergic signaling; Metabolic Epileptic Disorders"	"11"	"3"	"2432.6"	"1205.4"	"2318.7"	"2091.7"	"2169.8"	"2636.9"	"2085.7"	"2456.9"	"2019.9"	"3065.8"	"4218.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96DI7"	"U5 small nuclear ribonucleoprotein 40 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP40 PE=1 SV=1"	"0.000"	""	"56"	"12"	"28"	"12"	"357"	"39.3"	"8.10"	"5245.68"	"75.87"	"9"	"11"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf00400"	"9410"	"ENSG00000060688"	"SNRNP40"	"B4DQJ1; hsa:9410; O75938; O95320; Q96DI7"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"mRNA processing"	"3"	"0"	"1409.7"	"605.5"	"1142.2"	"1064.8"	"1080.9"	"1340.6"	"1048.0"	"1475.3"	"1419.7"	"3334.7"	"4902.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25205"	"DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3"	"0.000"	""	"27"	"17"	"38"	"17"	"808"	"90.9"	"5.77"	"6952.48"	"75.59"	"15"	"15"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855"	"4172"	"ENSG00000112118"	"MCM3"	"B4DWW4; hsa:4172; P25205; Q92660; Q9BTR3; Q9NUE7"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"Cell cycle; Retinoblastoma gene in cancer; Ciliary landscape; G1 to S cell cycle control; DNA replication"	"11"	"0"	"1220.9"	"518.1"	"1175.6"	"963.8"	"1058.6"	"1356.4"	"1103.6"	"1510.6"	"1310.8"	"2446.3"	"4318.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P00558"	"Phosphoglycerate kinase 1 OS=Homo sapiens OX=9606 GN=PGK1 PE=1 SV=3"	"0.000"	""	"42"	"13"	"24"	"13"	"417"	"44.6"	"8.10"	"2577.18"	"75.57"	"6"	"13"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;other membranes;cytosol"	"kinase activity;other molecular function"	"Pf00162"	"5230"	"ENSG00000102144"	"PGK1"	"A8K4W6; B7Z7A9; hsa:5230; P00558; Q5J7W1; Q6IBT6; Q8NI87"	"Glycolysis; Gluconeogenesis; Manipulation of host energy metabolism"	"Cori cycle; Photodynamic therapy-induced HIF-1 survival signaling; VEGFA-VEGFR2 signaling; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; Glycolysis in senescence; Warburg effect modulated by deubiquitinating enzymes and their substrates; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"13"	"0"	"674.0"	"284.5"	"502.4"	"423.9"	"534.1"	"562.2"	"518.8"	"618.4"	"697.1"	"3373.6"	"15028.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BXP5"	"Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1"	"0.000"	""	"26"	"21"	"42"	"21"	"876"	"100.6"	"5.96"	"6473.29"	"75.25"	"17"	"20"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04959, Pf12066"	"51593"	"ENSG00000087087"	"SRRT"	"A4D2E5; A4D2E6; A6NK22; B4DJL4; B4DZA6; hsa:51593; O95808; Q32MI4; Q6NT74; Q8TDQ5; Q9BWP6; Q9BXP4; Q9BXP5; Q9Y4S4"	"mRNA Splicing - Major Pathway; RNA polymerase II transcribes snRNA genes"	""	"2"	"0"	"2516.1"	"960.5"	"2214.2"	"1857.0"	"2128.7"	"2563.8"	"1889.0"	"2509.7"	"1923.4"	"3123.7"	"4707.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05198"	"Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3"	"0.000"	""	"42"	"13"	"34"	"13"	"315"	"36.1"	"5.08"	"4953.74"	"75.10"	"9"	"13"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf00575, Pf07541"	"1965"	"ENSG00000134001"	"EIF2S1"	"hsa:1965; P05198"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; ABC-family proteins mediated transport; Response of EIF2AK1 (HRI) to heme deficiency; PERK regulates gene expression; Recycling of eIF2:GDP; Response of EIF2AK4 (GCN2) to amino acid deficiency"	"Translation factors; Alzheimer's disease and miRNA effects; Brain-derived neurotrophic factor (BDNF) signaling pathway; Ebola virus infection in host; Nonalcoholic fatty liver disease; Measles virus infection; Unfolded protein response; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell; Alzheimer's disease"	"19"	"0"	"344.2"	"144.5"	"277.8"	"219.4"	"283.6"	"308.7"	"249.0"	"426.2"	"615.1"	"5689.9"	"13133.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P0DP25"	"Calmodulin-3 OS=Homo sapiens OX=9606 GN=CALM3 PE=1 SV=1"	"0.000"	""	"47"	"9"	"38"	"9"	"149"	"16.8"	"4.22"	"6354.47"	"74.54"	"7"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;mitochondrion;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf13499"	"801; 805; 808"	"ENSG00000160014"	"CALM3"	"hsa:801; hsa:805; hsa:808; P02593; P0DP25; P62158; P70667; P99014; Q13942; Q53S29; Q61379; Q61380; Q96HK3"	""	"Physiological and pathological hypertrophy of the heart; MicroRNAs in cardiomyocyte hypertrophy; Alzheimer's disease and miRNA effects; T cell receptor and co-stimulatory signaling; Cardiac hypertrophic response; Myometrial relaxation and contraction pathways; G protein signaling pathways; Ras signaling; Melanoma; Endochondral ossification; Endochondral ossification with skeletal dysplasias; CAMKK2 pathway; Glycogen synthesis and degradation; Neuroinflammation and glutamatergic signaling; Alzheimer's disease; G13 signaling pathway; Calcium regulation in cardiac cells"	"17"	"0"	"1380.4"	"697.9"	"1330.4"	"1155.4"	"1318.8"	"1464.0"	"1389.9"	"2385.7"	"3065.8"	"8571.0"	"10245.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P68363"	"Tubulin alpha-1B chain OS=Homo sapiens OX=9606 GN=TUBA1B PE=1 SV=1"	"0.000"	""	"40"	"13"	"38"	"2"	"451"	"50.1"	"5.06"	"6516.00"	"74.39"	"11"	"13"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00091, Pf03953"	"10376"	"ENSG00000123416"	"TUBA1B"	"hsa:10376; P04687; P05209; P68363; Q27I68; Q8WU19"	"Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Recruitment of NuMA to mitotic centrosomes; Recycling pathway of L1; COPI-dependent Golgi-to-ER retrograde traffic; MHC class II antigen presentation; Kinesins; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; RHO GTPases Activate Formins; Intraflagellar transport; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane; Gap junction assembly; Resolution of Sister Chromatid Cohesion; Formation of tubulin folding intermediates by CCT/TriC; Post-chaperonin tubulin folding pathway; RHO GTPases activate IQGAPs; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Carboxyterminal post-translational modifications of tubulin; HCMV Early Events; Assembly and cell surface presentation of NMDA receptors; Activation of AMPK downstream of NMDARs; Aggrephagy; EML4 and NUDC in mitotic spindle formation; Sealing of the nuclear envelope (NE) by ESCRT-III; Hedgehog 'off' state; RHOH GTPase cycle"	"Alzheimer's disease and miRNA effects; Pathogenic Escherichia coli infection; Allograft rejection; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"35"	"13"	"2066.0"	"850.2"	"1771.3"	"1571.2"	"1685.5"	"2042.5"	"1625.7"	"1798.8"	"1612.2"	"2883.4"	"5027.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43776"	"Asparagine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=NARS1 PE=1 SV=1"	"0.000"	""	"38"	"20"	"33"	"20"	"548"	"62.9"	"6.25"	"6196.75"	"74.36"	"11"	"17"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00152, Pf01336"	"4677"	"ENSG00000134440"	"NARS1"	"B4DG16; hsa:4677; O43776; Q53GU6"	"Cytosolic tRNA aminoacylation"	"Photodynamic therapy-induced unfolded protein response"	"2"	"0"	"571.0"	"247.2"	"522.6"	"452.7"	"518.7"	"540.7"	"448.6"	"595.4"	"728.5"	"6368.7"	"15193.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60264"	"SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1"	"0.000"	""	"24"	"21"	"42"	"13"	"1052"	"121.8"	"8.09"	"6465.90"	"74.24"	"19"	"21"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf09110, Pf09111"	"8467"	"ENSG00000153147"	"SMARCA5"	"hsa:8467; O60264"	"Deposition of new CENPA-containing nucleosomes at the centromere; B-WICH complex positively regulates rRNA expression; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; NoRC negatively regulates rRNA expression"	"10q11.21q11.23 copy number variation syndrome"	"5"	"8"	"1132.8"	"464.0"	"999.0"	"847.1"	"979.8"	"1125.6"	"790.7"	"1121.7"	"876.9"	"4641.8"	"12503.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12905"	"Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2"	"0.000"	""	"53"	"12"	"34"	"12"	"390"	"43.0"	"5.26"	"5650.65"	"73.88"	"7"	"11"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf07528"	"3608"	"ENSG00000143621"	"ILF2"	"A6NDB0; B2R8G7; hsa:3608; Q12905; Q5SR10; Q5SR11; Q7L7R3; Q9BWD4; Q9P1N0"	"Neutrophil degranulation"	"B cell receptor signaling pathway"	"2"	"0"	"1413.4"	"433.9"	"912.8"	"830.3"	"901.8"	"992.0"	"794.4"	"993.1"	"853.2"	"1291.7"	"2102.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52272"	"Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3"	"0.000"	""	"26"	"15"	"38"	"15"	"730"	"77.5"	"8.70"	"6786.25"	"73.70"	"13"	"15"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf11532"	"4670"	"ENSG00000099783"	"HNRNPM"	"hsa:4670; P52272; Q15584; Q8WZ44; Q96H56; Q9BWL9; Q9Y492"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA; FGFR2 alternative splicing"	"mRNA processing"	"4"	"0"	"3207.7"	"831.6"	"1749.5"	"1491.3"	"1751.0"	"1988.3"	"1573.5"	"2011.4"	"1755.3"	"3339.5"	"6592.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22102"	"Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1"	"0.000"	""	"20"	"17"	"32"	"17"	"1010"	"107.7"	"6.70"	"4587.84"	"72.84"	"12"	"16"	"other metabolic processes;developmental processes;other biological processes"	"cytosol"	"other molecular function"	"Pf00551, Pf00586, Pf01071, Pf02769, Pf02843, Pf02844"	"2618"	"ENSG00000159131; ENSG00000262473"	"GART"	"A8K945; A8KA32; D3DSF3; D3DSF4; hsa:2618; O14659; P22102; Q52M77"	"Purine ribonucleoside monophosphate biosynthesis"	"Folate metabolism; One-carbon metabolism; Metabolic reprogramming in colon cancer"	"4"	"0"	"637.5"	"236.9"	"545.2"	"437.1"	"582.9"	"662.4"	"490.1"	"1284.1"	"2365.5"	"8807.8"	"15091.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14618"	"Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4"	"0.000"	""	"33"	"14"	"32"	"14"	"531"	"57.9"	"7.84"	"6380.30"	"72.68"	"11"	"13"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00224, Pf02887"	"5315"	"ENSG00000067225"	"PKM"	"A6NFK3; B2R5N8; B3KRY0; B4DFX8; B4DUU6; hsa:5315; P14618; P14786; Q53GK4; Q96E76; Q9BWB5; Q9UCV6; Q9UPF2"	"Neutrophil degranulation"	"Photodynamic therapy-induced HIF-1 survival signaling; Amino acid metabolism; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; Glycolysis in senescence; Glucose metabolism in triple-negative breast cancer cells; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"10"	"0"	"1931.2"	"769.0"	"1810.9"	"1517.9"	"1643.9"	"1966.2"	"1426.8"	"1906.3"	"1518.5"	"2758.2"	"4340.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P31946"	"14-3-3 protein beta/alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3"	"0.000"	""	"57"	"12"	"43"	"7"	"246"	"28.1"	"4.83"	"7337.77"	"72.29"	"12"	"12"	"transport;signal transduction;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00244"	"7529"	"ENSG00000166913"	"YWHAB"	"A8K9K2; E1P616; hsa:7529; P31946"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Signaling by BRAF and RAF1 fusions; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; Regulation of localization of FOXO transcription factors; mTORC1-mediated signalling; TP53 Regulates Metabolic Genes; Signaling by Hippo; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RAF activation; SHOC2 M1731 mutant abolishes MRAS complex function; Gain-of-function MRAS complexes activate RAF signaling; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Rap1 signalling; Negative regulation of MAPK pathway; Frs2-mediated activation; ARMS-mediated activation; Activation of BAD and translocation to mitochondria ; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"	"Cell cycle; IL-3 signaling pathway; Myometrial relaxation and contraction pathways; Hepatitis B infection; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"33"	"5"	"1939.1"	"1008.5"	"1963.4"	"1835.5"	"1875.5"	"2297.8"	"1891.5"	"2276.7"	"1796.9"	"3168.3"	"4793.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26368"	"Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4"	"0.000"	""	"24"	"10"	"32"	"10"	"475"	"53.5"	"9.09"	"5545.22"	"72.20"	"8"	"10"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"11338"	"ENSG00000063244"	"U2AF2"	"hsa:11338; P26368; Q96HC5"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"mRNA processing; Warburg effect modulated by deubiquitinating enzymes and their substrates"	"6"	"0"	"3209.3"	"1070.0"	"2236.1"	"1826.5"	"2111.4"	"2987.6"	"2786.0"	"4274.3"	"3421.2"	"4273.9"	"7277.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q71U36"	"Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1"	"0.000"	""	"37"	"12"	"36"	"1"	"451"	"50.1"	"5.06"	"6210.99"	"72.09"	"10"	"12"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00091, Pf03953"	"7846"	"ENSG00000167552"	"TUBA1A"	"A8K0B8; G3V1U9; hsa:7846; P04687; P05209; Q71U36"	"COPI-dependent Golgi-to-ER retrograde traffic; Separation of Sister Chromatids; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Kinesins; The role of GTSE1 in G2/M progression after G2 checkpoint; HCMV Early Events; Recycling pathway of L1; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recruitment of mitotic centrosome proteins and complexes; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Formation of tubulin folding intermediates by CCT/TriC; Prefoldin mediated transfer of substrate  to CCT/TriC; Hedgehog 'off' state; COPI-mediated anterograde transport; Intraflagellar transport; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane; Gap junction assembly; Post-chaperonin tubulin folding pathway; RHO GTPases activate IQGAPs; COPI-independent Golgi-to-ER retrograde traffic; Carboxyterminal post-translational modifications of tubulin; Assembly and cell surface presentation of NMDA receptors; Activation of AMPK downstream of NMDARs; Aggrephagy; Sealing of the nuclear envelope (NE) by ESCRT-III"	"Alzheimer's disease and miRNA effects; Pathogenic Escherichia coli infection; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease; PAFAH1B1 copy number variation"	"41"	"0"	"43.6"	"13.3"	"48.4"	"39.7"	"48.1"	"46.8"	"36.0"	"42.1"	"38.3"	"69.2"	"165.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62805"	"Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2"	"0.000"	""	"58"	"12"	"43"	"12"	"103"	"11.4"	"11.36"	"8241.07"	"71.97"	"11"	"10"	"cell organization and biogenesis;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf15511"	"121504; 554313; 8294; 8359; 8360; 8361; 8362; 8363; 8364; 8365; 8366; 8367; 8368; 8370"	"ENSG00000158406; ENSG00000197061; ENSG00000197238; ENSG00000197837; ENSG00000270276; ENSG00000270882; ENSG00000273542; ENSG00000274618; ENSG00000275126; ENSG00000276180; ENSG00000276966; ENSG00000277157; ENSG00000278637; ENSG00000278705"	"H4C1; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9"	"A2VCL0; hsa:121504; hsa:554313; hsa:8294; hsa:8359; hsa:8360; hsa:8361; hsa:8362; hsa:8363; hsa:8364; hsa:8365; hsa:8366; hsa:8367; hsa:8368; hsa:8370; P02304; P02305; P62805; Q6DRA9; Q6FGB8; Q6NWP7"	"Meiotic synapsis; Estrogen-dependent gene expression; HDACs deacetylate histones; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; Meiotic recombination; SUMOylation of chromatin organization proteins; HCMV Late Events; HCMV Early Events; Transcriptional regulation by small RNAs; Amyloid fiber formation; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Deposition of new CENPA-containing nucleosomes at the centromere; B-WICH complex positively regulates rRNA expression; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Formation of the beta-catenin:TCF transactivating complex; Oxidative Stress Induced Senescence; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Pre-NOTCH Transcription and Translation; Senescence-Associated Secretory Phenotype (SASP); RMTs methylate histone arginines; HDMs demethylate histones; PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; HATs acetylate histones; RNA Polymerase I Promoter Escape; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Packaging Of Telomere Ends; Condensation of Prophase Chromosomes; DNA Damage/Telomere Stress Induced Senescence; DNA methylation; Nonhomologous End-Joining (NHEJ); RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	"Gastric cancer network 1; Histone modifications; 22q11.2 copy number variation syndrome; Male infertility; Type II interferon signaling"	"50"	"0"	"2274.3"	"889.1"	"1902.1"	"1711.6"	"1757.4"	"2583.3"	"2085.3"	"2322.6"	"2183.8"	"3996.3"	"4347.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07900"	"Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5"	"0.000"	""	"28"	"21"	"43"	"8"	"732"	"84.6"	"5.02"	"6480.66"	"71.34"	"18"	"21"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"non-structural extracellular;extracellular matrix;plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00183, Pf02518"	"3320"	"ENSG00000080824"	"HSP90AA1"	"A8K500; B3KPJ9; hsa:3320; P07900; Q2PP14; Q5CAQ6; Q5CAQ7; Q9BVQ5"	"Regulation of actin dynamics for phagocytic cup formation; Interleukin-4 and Interleukin-13 signaling; Potential therapeutics for SARS; The role of GTSE1 in G2/M progression after G2 checkpoint; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recruitment of NuMA to mitotic centrosomes; Aggrephagy; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Extra-nuclear estrogen signaling; Neutrophil degranulation; vRNP Assembly; Estrogen-dependent gene expression; Regulation of necroptotic cell death; Downregulation of ERBB2 signaling; Signaling by ERBB2 KD Mutants; Signaling by ERBB2 TMD/JMD mutants; Sema3A PAK dependent Axon repulsion; DDX58/IFIH1-mediated induction of interferon-alpha/beta; PIWI-interacting RNA (piRNA) biogenesis; VEGFR2 mediated vascular permeability; RHOBTB2 GTPase cycle; Chaperone Mediated Autophagy; HSF1 activation; Attenuation phase; eNOS activation; Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; Constitutive Signaling by EGFRvIII; Signaling by ERBB2 ECD mutants; Uptake and function of diphtheria toxin; Constitutive Signaling by Overexpressed ERBB2; Scavenging by Class F Receptors; Drug-mediated inhibition of ERBB2 signaling; Resistance of ERBB2 KD mutants to trastuzumab; Resistance of ERBB2 KD mutants to sapitinib; Resistance of ERBB2 KD mutants to tesevatinib; Resistance of ERBB2 KD mutants to neratinib; Resistance of ERBB2 KD mutants to osimertinib; Resistance of ERBB2 KD mutants to afatinib; Resistance of ERBB2 KD mutants to AEE788; Resistance of ERBB2 KD mutants to lapatinib; Drug resistance in ERBB2 TMD/JMD mutants"	"Nucleotide-binding oligomerization domain (NOD) pathway; TNF-alpha signaling pathway; Corticotropin-releasing hormone signaling pathway; Aryl hydrocarbon receptor pathway; Ebstein-Barr virus LMP1 signaling; Aryl hydrocarbon receptor pathway; Constitutive androstane receptor pathway; Pregnane X receptor pathway; Glucocorticoid receptor pathway; Nuclear receptors meta-pathway; NRF2 pathway; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Th17 cell differentiation pathway"	"67"	"0"	"894.0"	"284.1"	"585.0"	"463.2"	"641.8"	"605.6"	"529.7"	"673.8"	"569.0"	"869.4"	"1558.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12874"	"Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1"	"0.000"	""	"39"	"18"	"38"	"17"	"501"	"58.8"	"5.38"	"7262.15"	"71.14"	"15"	"14"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf11931, Pf12108, Pf13297, Pf16837"	"10946"	"ENSG00000183431"	"SF3A3"	"D3DPT5; hsa:10946; Q12874; Q15460; Q5VT87"	"mRNA Splicing - Major Pathway"	"Exercise-induced circadian regulation; mRNA processing"	"3"	"1"	"3850.6"	"1441.5"	"3496.7"	"2846.2"	"3313.2"	"4077.8"	"2671.7"	"3571.1"	"2517.7"	"4861.7"	"8328.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42285"	"Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3"	"0.000"	""	"17"	"13"	"29"	"13"	"1042"	"117.7"	"6.52"	"3663.53"	"70.81"	"7"	"13"	"RNA metabolism OR transcription;other metabolic processes;stress response"	"nucleus"	"other molecular function"	"Pf00270, Pf00271, Pf08148, Pf13234"	"23517"	"ENSG00000039123"	"MTREX"	"hsa:23517; P42285; Q2M386; Q6MZZ8; Q6P170; Q8N5R0; Q8TAG2"	"Major pathway of rRNA processing in the nucleolus and cytosol; mRNA Splicing - Major Pathway"	""	"2"	"0"	"921.3"	"381.0"	"862.7"	"730.5"	"845.9"	"1000.2"	"724.2"	"946.8"	"756.5"	"2888.1"	"9553.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96N67"	"Dedicator of cytokinesis protein 7 OS=Homo sapiens OX=9606 GN=DOCK7 PE=1 SV=4"	"0.000"	""	"11"	"19"	"31"	"19"	"2140"	"242.4"	"6.80"	"4714.19"	"70.35"	"12"	"19"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"other cell component"	"enzyme regulator activity;other molecular function"	"Pf06920, Pf11878, Pf14429, Pf20421, Pf20422"	"85440"	"ENSG00000116641"	"DOCK7"	"hsa:85440; Q00M63; Q2PPY7; Q45RE8; Q45RE9; Q5T1B9; Q5T1C0; Q6ZV32; Q8TB82; Q96N67; Q96NG6; Q96NI0; Q9C092"	"RAC1 GTPase cycle; CDC42 GTPase cycle; Factors involved in megakaryocyte development and platelet production; MET activates RAP1 and RAC1"	""	"4"	"0"	"891.7"	"390.7"	"881.5"	"780.2"	"801.9"	"1023.1"	"923.1"	"1535.1"	"1320.7"	"4883.9"	"13444.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UQ80"	"Proliferation-associated protein 2G4 OS=Homo sapiens OX=9606 GN=PA2G4 PE=1 SV=3"	"0.000"	""	"40"	"17"	"45"	"17"	"394"	"43.8"	"6.55"	"8130.09"	"69.96"	"17"	"16"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00557"	"5036"	"ENSG00000170515"	"PA2G4"	"hsa:5036; O43846; Q9UM59; Q9UQ80"	"Neutrophil degranulation"	""	"1"	"0"	"2016.9"	"1081.0"	"2005.6"	"1993.5"	"2051.9"	"2605.3"	"1819.2"	"2349.3"	"1869.5"	"3760.5"	"9906.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q07666"	"KH domain-containing, RNA-binding, signal transduction-associated protein 1 OS=Homo sapiens OX=9606 GN=KHDRBS1 PE=1 SV=1"	"0.000"	""	"19"	"11"	"36"	"11"	"443"	"48.2"	"8.66"	"7826.97"	"69.92"	"8"	"9"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf16274, Pf16568"	"10657"	"ENSG00000121774"	"KHDRBS1"	"D3DPP3; hsa:10657; Q07666; Q6PJX7; Q8NB97; Q99760"	"PTK6 Regulates Proteins Involved in RNA Processing"	"Leptin signaling pathway; Primary ovarian insufficiency"	"3"	"0"	"2430.7"	"1115.9"	"1967.6"	"1692.4"	"1954.7"	"2286.8"	"1694.0"	"2264.4"	"1686.5"	"2704.9"	"4423.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2W1"	"Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2"	"0.000"	""	"24"	"20"	"41"	"19"	"955"	"108.6"	"10.15"	"6896.87"	"69.25"	"19"	"19"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf15440"	"9967"	"ENSG00000054118"	"THRAP3"	"D3DPS5; hsa:9967; Q5VTK6; Q9Y2W1"	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation"	"Interactome of polycomb repressive complex 2 (PRC2)"	"3"	"1"	"3720.3"	"1211.9"	"2337.1"	"2139.2"	"2350.0"	"2664.2"	"2421.5"	"3611.6"	"2519.3"	"3846.7"	"6356.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14979"	"Heterogeneous nuclear ribonucleoprotein D-like OS=Homo sapiens OX=9606 GN=HNRNPDL PE=1 SV=3"	"0.000"	""	"22"	"10"	"41"	"7"	"420"	"46.4"	"9.57"	"8268.36"	"68.55"	"10"	"9"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity"	"Pf00076"	"9987"	"ENSG00000152795"	"HNRNPDL"	"hsa:9987; O14979; Q6SPF2; Q7KZ74; Q7KZ75; Q96IM0; Q96S43"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	""	"1"	"0"	"1672.1"	"410.4"	"991.5"	"754.0"	"884.8"	"1084.3"	"821.5"	"1109.1"	"1053.9"	"1639.5"	"2490.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35527"	"Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3"	"0.000"	""	"21"	"11"	"29"	"10"	"623"	"62.0"	"5.24"	"4653.72"	"68.40"	"9"	"10"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	"cytoskeletal activity"	"Pf00038"	"3857"	"ENSG00000171403"	"KRT9"	"hsa:3857; O00109; P35527; Q0IJ47; Q14665"	"Formation of the cornified envelope"	""	"2"	"0"	"479.2"	"2047.2"	"621.5"	"292.7"	"3779.9"	"469.9"	"267.5"	"616.5"	"2171.9"	"3209.3"	"3506.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95248"	"Myotubularin-related protein 5 OS=Homo sapiens OX=9606 GN=SBF1 PE=1 SV=4"	"0.000"	""	"13"	"19"	"34"	"18"	"1868"	"208.3"	"6.90"	"5700.58"	"68.33"	"12"	"18"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf02141, Pf02893, Pf03456, Pf06602, Pf12335"	"6305"	"ENSG00000100241"	"SBF1"	"A0A024R4Z9; A6PVG9; G5E933; hsa:6305; O60228; O95248; Q5JXD8; Q5PPM2; Q96GR9; Q9UGB8"	"RAB GEFs exchange GTP for GDP on RABs; Synthesis of PIPs at the ER membrane"	""	"2"	"1"	"854.9"	"378.4"	"721.9"	"633.2"	"737.5"	"827.7"	"816.8"	"2405.0"	"3514.8"	"8309.4"	"12431.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08708"	"40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2"	"0.000"	""	"56"	"6"	"19"	"6"	"135"	"15.5"	"9.85"	"1417.12"	"68.20"	"3"	"6"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00833"	"6218"	"ENSG00000182774; ENSG00000278229"	"RPS17"	"B2R4U4; hsa:6218; P08708; P0CW22"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"943.3"	"494.0"	"850.4"	"773.2"	"825.9"	"1094.9"	"791.3"	"1015.3"	"789.1"	"1128.9"	"1678.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NYF8"	"Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2"	"0.000"	""	"18"	"15"	"37"	"14"	"920"	"106.1"	"9.98"	"7872.16"	"67.02"	"13"	"13"	"stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf15440"	"9774"	"ENSG00000029363"	"BCLAF1"	"A2RU75; B7ZM58; E1P586; hsa:9774; Q14673; Q86WU6; Q86WY0; Q9NYF8"	""	"Interactome of polycomb repressive complex 2 (PRC2)"	"1"	"0"	"4302.5"	"1209.3"	"2665.8"	"2311.8"	"2748.5"	"3286.8"	"3192.9"	"4631.5"	"2973.2"	"3831.1"	"6673.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08621"	"U1 small nuclear ribonucleoprotein 70 kDa OS=Homo sapiens OX=9606 GN=SNRNP70 PE=1 SV=2"	"0.000"	""	"28"	"15"	"39"	"15"	"437"	"51.5"	"9.94"	"6203.98"	"66.97"	"12"	"15"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf12220"	"6625"	"ENSG00000104852"	"SNRNP70"	"B3KUA3; hsa:6625; P08621; P78493; P78494; Q15364; Q15686; Q15687; Q15689; Q99377; Q9UE45; Q9UE46; Q9UE47; Q9UE48; Q9UFQ6"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"0"	"4254.6"	"1653.0"	"2825.4"	"2305.8"	"2668.6"	"3052.6"	"2223.2"	"2912.0"	"2460.2"	"4024.6"	"5508.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P28370"	"Probable global transcription activator SNF2L1 OS=Homo sapiens OX=9606 GN=SMARCA1 PE=1 SV=2"	"0.000"	""	"19"	"19"	"37"	"11"	"1054"	"122.5"	"8.09"	"5913.29"	"66.70"	"16"	"18"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf09110, Pf09111"	"6594"	"ENSG00000102038"	"SMARCA1"	"hsa:6594; P28370; Q5JV41; Q5JV42"	""	"Nuclear receptors meta-pathway; Rett syndrome causing genes"	"2"	"0"	"579.1"	"389.2"	"531.8"	"428.2"	"513.3"	"568.3"	"422.6"	"642.6"	"708.9"	"3989.6"	"8515.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62318"	"Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1"	"0.000"	""	"56"	"7"	"35"	"7"	"126"	"13.9"	"10.32"	"7946.70"	"66.49"	"5"	"5"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01423"	"6634"	"ENSG00000100028"	"SNRPD3"	"B4DJP7; B5BU13; hsa:6634; P43331; P62318"	"mRNA Splicing - Major Pathway; SARS-CoV-2 modulates host translation machinery; snRNP Assembly; RNA Polymerase II Transcription Termination; mRNA Splicing - Minor Pathway; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"mRNA processing"	"8"	"0"	"2564.1"	"1204.5"	"1824.1"	"1542.9"	"1769.8"	"1917.3"	"1611.2"	"1932.3"	"1746.6"	"2433.3"	"3493.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H9Y6"	"DNA-directed RNA polymerase I subunit RPA2 OS=Homo sapiens OX=9606 GN=POLR1B PE=1 SV=2"	"0.000"	""	"13"	"13"	"35"	"13"	"1135"	"128.1"	"7.83"	"5675.49"	"66.41"	"12"	"13"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00562, Pf04560, Pf04561, Pf04563, Pf04565, Pf06883"	"84172"	"ENSG00000125630"	"POLR1B"	"B7Z6Y7; B7Z823; F5GZX4; F8W898; hsa:84172; Q2TAM4; Q585T5; Q6ZRR2; Q9H9D3; Q9H9Y6"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"Pyrimidine metabolism; Eukaryotic transcription initiation; 2q13 copy number variation syndrome"	"8"	"0"	"579.1"	"281.2"	"496.6"	"428.8"	"531.1"	"576.9"	"461.6"	"978.9"	"1853.4"	"5926.9"	"10397.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P43243"	"Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2"	"0.000"	""	"22"	"19"	"41"	"19"	"847"	"94.6"	"6.25"	"7117.18"	"66.36"	"16"	"16"	"stress response;developmental processes;other biological processes"	"other membranes;nucleus"	"nucleic acid binding activity;other molecular function"	""	"9782"	"ENSG00000015479"	"MATR3"	"B7ZAV5; D3DQC3; hsa:9782; P43243; Q9UHW0; Q9UQ27"	""	""	"0"	"0"	"5369.8"	"1239.3"	"2585.9"	"2107.4"	"2676.7"	"2860.2"	"2375.8"	"2964.9"	"2584.5"	"3957.0"	"8312.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P24534"	"Elongation factor 1-beta OS=Homo sapiens OX=9606 GN=EEF1B2 PE=1 SV=3"	"0.000"	""	"71"	"14"	"37"	"11"	"225"	"24.7"	"4.67"	"7533.58"	"65.31"	"11"	"11"	"protein metabolism;other metabolic processes"	"cytosol;other cell component"	"enzyme regulator activity;nucleic acid binding activity"	"Pf00736, Pf10587"	"1933"	"ENSG00000114942; ENSG00000283391"	"EEF1B2"	"A8K795; hsa:1933; P24534; Q6IBH9"	"Eukaryotic Translation Elongation"	"Translation factors"	"2"	"4"	"3342.7"	"1570.7"	"3491.1"	"2801.5"	"3011.6"	"3796.7"	"2549.7"	"3507.9"	"2655.5"	"4544.5"	"7143.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55795"	"Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1"	"0.000"	""	"31"	"11"	"38"	"4"	"449"	"49.2"	"6.30"	"6300.51"	"64.73"	"10"	"10"	"other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00076, Pf08080"	"3188"	"ENSG00000126945"	"HNRNPH2"	"A1L400; hsa:3188; P55795; Q9HHA7"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"mRNA processing"	"3"	"0"	"305.9"	"107.0"	"281.7"	"218.1"	"239.1"	"316.1"	"217.3"	"272.3"	"260.7"	"414.2"	"616.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27695"	"DNA-(apurinic or apyrimidinic site) lyase OS=Homo sapiens OX=9606 GN=APEX1 PE=1 SV=2"	"0.000"	""	"48"	"11"	"25"	"11"	"318"	"35.5"	"8.12"	"5187.56"	"64.23"	"8"	"11"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;mitochondrion;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03372"	"328"	"ENSG00000100823"	"APEX1"	"hsa:328; P27695; Q969L5; Q99775"	"Displacement of DNA glycosylase by APEX1; POLB-Dependent Long Patch Base Excision Repair; PCNA-Dependent Long Patch Base Excision Repair; Abasic sugar-phosphate removal via the single-nucleotide replacement pathway"	"Thyroid stimulating hormone (TSH) signaling pathway; Spinal cord injury; Base excision repair; DNA repair pathways, full network"	"10"	"0"	"575.9"	"282.6"	"531.3"	"511.6"	"494.3"	"650.9"	"518.9"	"741.4"	"721.2"	"3988.7"	"8587.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NE71"	"ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2"	"0.000"	""	"17"	"11"	"26"	"11"	"845"	"95.9"	"6.80"	"4229.44"	"64.15"	"6"	"11"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00005, Pf12848"	"23"	"ENSG00000204574; ENSG00000206490; ENSG00000225989; ENSG00000231129; ENSG00000232169; ENSG00000236149; ENSG00000236342"	"ABCF1"	"A2BF75; hsa:23; O14897; Q69YP6; Q8NE71"	"ABC-family proteins mediated transport"	"IL-18 signaling pathway"	"2"	"0"	"559.8"	"267.5"	"499.2"	"453.5"	"502.2"	"588.2"	"459.3"	"781.5"	"686.8"	"3315.8"	"11321.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53582"	"Methionine aminopeptidase 1 OS=Homo sapiens OX=9606 GN=METAP1 PE=1 SV=2"	"0.000"	""	"38"	"11"	"21"	"11"	"386"	"43.2"	"7.17"	"2709.10"	"63.86"	"5"	"11"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00557, Pf15801"	"23173"	"ENSG00000164024"	"METAP1"	"B4E2E6; hsa:23173; P53582"	"Inactivation, recovery and regulation of the phototransduction cascade"	""	"1"	"0"	"411.9"	"178.8"	"380.6"	"335.7"	"360.1"	"461.4"	"338.7"	"576.9"	"829.9"	"3300.1"	"5523.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P38159"	"RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX PE=1 SV=3"	"0.000"	""	"27"	"9"	"40"	"4"	"391"	"42.3"	"10.05"	"7098.64"	"63.81"	"8"	"9"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08081"	"27316"	"ENSG00000147274"	"RBMX"	"B4E3U4; D3DWH0; E9PG86; hsa:27316; P38159; Q5JQ67; Q8N8Y7; Q969R3"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA; RND2 GTPase cycle; RND3 GTPase cycle; RND1 GTPase cycle; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle"	"mRNA processing"	"8"	"4"	"4289.3"	"1103.5"	"1920.1"	"1525.4"	"2059.8"	"1989.9"	"1693.9"	"2203.5"	"2056.1"	"3045.1"	"5033.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43795"	"Unconventional myosin-Ib OS=Homo sapiens OX=9606 GN=MYO1B PE=1 SV=3"	"0.000"	""	"14"	"13"	"22"	"12"	"1136"	"131.9"	"9.38"	"2396.38"	"63.80"	"6"	"13"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00063, Pf00612, Pf06017"	"4430"	"ENSG00000128641"	"MYO1B"	"hsa:4430; O43794; O43795; Q7Z6L5"	""	""	"0"	"0"	"639.2"	"250.3"	"493.9"	"457.6"	"527.3"	"585.3"	"448.6"	"745.5"	"776.1"	"3857.0"	"7815.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L7X3"	"Serine/threonine-protein kinase TAO1 OS=Homo sapiens OX=9606 GN=TAOK1 PE=1 SV=1"	"0.000"	""	"18"	"17"	"36"	"13"	"1001"	"116.0"	"7.65"	"6384.34"	"62.18"	"14"	"15"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;cytoskeletal activity;kinase activity;other molecular function"	"Pf00069"	"57551"	"ENSG00000160551"	"TAOK1"	"A2RUT8; B7ZLV6; hsa:57551; Q7L7X3; Q96L75; Q9H2K7; Q9H7S5; Q9P2I6"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"Microtubule cytoskeleton regulation; MAPK signaling pathway"	"8"	"3"	"799.0"	"357.4"	"766.9"	"706.4"	"799.7"	"1192.4"	"1304.8"	"2248.1"	"2284.9"	"6362.9"	"6828.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P10809"	"60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2"	"0.000"	""	"28"	"16"	"39"	"16"	"573"	"61.0"	"5.87"	"7606.08"	"61.69"	"16"	"15"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00118"	"3329"	"ENSG00000144381"	"HSPD1"	"B2R5M6; B7Z712; hsa:3329; P10809; Q38L19; Q9UCR6"	"Mitochondrial protein import; TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"	"Apoptosis-related network due to altered Notch3 in ovarian cancer; 8p23.1 copy number variation syndrome; Sudden infant death syndrome (SIDS) susceptibility pathways"	"5"	"0"	"3552.5"	"1138.9"	"2495.7"	"1849.2"	"2496.9"	"2629.5"	"2104.8"	"2601.0"	"2064.0"	"3741.8"	"7587.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q05639"	"Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1"	"0.000"	""	"35"	"11"	"32"	"3"	"463"	"50.4"	"9.03"	"4718.73"	"61.32"	"8"	"10"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03143, Pf03144"	"1917"	"ENSG00000101210"	"EEF1A2"	"B5BUF3; E1P5J1; hsa:1917; P54266; Q05639; Q0VGC7"	"Eukaryotic Translation Elongation"	"Translation factors"	"2"	"0"	"297.7"	"125.9"	"246.5"	"212.0"	"234.5"	"314.2"	"208.3"	"309.2"	"250.3"	"539.4"	"863.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14678"	"Small nuclear ribonucleoprotein-associated proteins B and B' OS=Homo sapiens OX=9606 GN=SNRPB PE=1 SV=2"	"0.000"	""	"22"	"7"	"31"	"7"	"240"	"24.6"	"11.19"	"4234.18"	"60.97"	"5"	"7"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01423"	"6628"	"ENSG00000125835"	"SNRPB"	"hsa:6628; P14678; Q15490; Q6IB35; Q9UIS5"	"snRNP Assembly; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; SARS-CoV-2 modulates host translation machinery; mRNA Splicing - Minor Pathway; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"mRNA processing"	"8"	"0"	"2870.0"	"995.8"	"1957.2"	"1607.3"	"1979.4"	"2264.1"	"1805.3"	"2333.7"	"1890.0"	"3062.1"	"4609.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P15924"	"Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3"	"0.000"	""	"7"	"21"	"37"	"21"	"2871"	"331.6"	"6.81"	"5681.68"	"60.92"	"17"	"20"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00681, Pf17902, Pf18373"	"1832"	"ENSG00000096696"	"DSP"	"B2RTT2; D7RX09; hsa:1832; O75993; P15924; Q14189; Q9UHN4"	"Neutrophil degranulation; Formation of the cornified envelope; RND3 GTPase cycle; RND1 GTPase cycle; Apoptotic cleavage of cell adhesion  proteins"	"Arrhythmogenic right ventricular cardiomyopathy; Lung fibrosis; Epithelial to mesenchymal transition in colorectal cancer"	"9"	"0"	"2779.3"	"1320.9"	"2010.5"	"1712.7"	"2287.7"	"2238.5"	"1449.2"	"2334.6"	"1836.2"	"3343.9"	"5661.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TCS8"	"Polyribonucleotide nucleotidyltransferase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PNPT1 PE=1 SV=2"	"0.000"	""	"25"	"14"	"30"	"14"	"783"	"85.9"	"7.77"	"5401.71"	"60.35"	"11"	"14"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;mitochondrion;ER/Golgi;translational apparatus;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf01138, Pf03725, Pf03726"	"87178"	"ENSG00000138035"	"PNPT1"	"hsa:87178; Q53SU0; Q68CN1; Q7Z7D1; Q8IWX1; Q8TCS8; Q96T05; Q9BRU3; Q9BVX0"	""	"Pyrimidine metabolism; miRNA degrading enzymes"	"2"	"0"	"1242.8"	"599.8"	"1171.0"	"996.0"	"1100.6"	"1283.5"	"908.2"	"1155.2"	"984.3"	"1855.4"	"3466.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09661"	"U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2"	"0.000"	""	"57"	"15"	"37"	"15"	"255"	"28.4"	"8.62"	"6981.55"	"59.94"	"13"	"12"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf14580"	"6627"	"ENSG00000131876"	"SNRPA1"	"B2R5I6; hsa:6627; P09661; Q8TBD2"	"mRNA Splicing - Major Pathway; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"mRNA processing"	"3"	"0"	"3243.7"	"1492.5"	"2548.3"	"2057.0"	"2464.9"	"2686.1"	"2161.7"	"2786.1"	"2149.9"	"3018.2"	"4530.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92499"	"ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2"	"0.000"	""	"28"	"13"	"24"	"13"	"740"	"82.4"	"7.23"	"4653.80"	"59.25"	"9"	"13"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf00622"	"1653"	"ENSG00000079785"	"DDX1"	"B4DME8; B4DPN6; hsa:1653; Q92499"	"tRNA processing in the nucleus"	"DDX1 as a regulatory component of the Drosha microprocessor; mRNA processing"	"3"	"0"	"893.5"	"342.2"	"768.4"	"652.9"	"708.8"	"875.8"	"566.5"	"860.9"	"624.3"	"1301.4"	"2408.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q00688"	"Peptidyl-prolyl cis-trans isomerase FKBP3 OS=Homo sapiens OX=9606 GN=FKBP3 PE=1 SV=1"	"0.000"	""	"41"	"12"	"32"	"12"	"224"	"25.2"	"9.28"	"6458.61"	"58.99"	"11"	"10"	""	"nucleus"	"other molecular function"	"Pf00254, Pf18410"	"2287"	"ENSG00000100442"	"FKBP3"	"B2R4Q9; hsa:2287; Q00688; Q14317"	""	""	"0"	"0"	"1207.3"	"594.0"	"1146.2"	"1079.2"	"1014.7"	"1276.2"	"958.5"	"1695.1"	"2292.1"	"10061.5"	"11594.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75937"	"DnaJ homolog subfamily C member 8 OS=Homo sapiens OX=9606 GN=DNAJC8 PE=1 SV=2"	"0.000"	""	"36"	"9"	"22"	"9"	"253"	"29.8"	"9.06"	"2880.49"	"58.60"	"6"	"9"	""	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00226"	"22826"	"ENSG00000126698; ENSG00000285317"	"DNAJC8"	"B4DUU4; D3DPM0; hsa:22826; O75937; Q6IBA4; Q8N4Z5; Q9P051; Q9P067"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"0"	"816.1"	"320.9"	"658.6"	"612.4"	"702.6"	"798.8"	"676.0"	"922.4"	"936.1"	"4046.5"	"8173.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62136"	"Serine/threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1"	"0.000"	""	"37"	"11"	"31"	"3"	"330"	"37.5"	"6.33"	"5880.87"	"58.53"	"10"	"11"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00149, Pf16891"	"5499"	"ENSG00000172531"	"PPP1CA"	"A6NNR3; B2R908; hsa:5499; P08129; P20653; P22802; P62136; Q07161"	"Triglyceride catabolism; Circadian Clock; Downregulation of TGF-beta receptor signaling; DARPP-32 events"	"Sphingolipid pathway; Nicotine effect on dopaminergic neurons; Common pathways underlying drug addiction; Focal adhesion; VEGFA-VEGFR2 signaling; Hippo-Merlin signaling dysregulation; Fragile X syndrome; Netrin-UNC5B signaling pathway; Neuroinflammation and glutamatergic signaling"	"13"	"9"	"2003.8"	"1010.8"	"1851.0"	"1674.6"	"1839.5"	"2049.8"	"1579.3"	"2181.3"	"1970.1"	"3549.0"	"4339.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5S2"	"Serine/threonine-protein kinase MRCK beta OS=Homo sapiens OX=9606 GN=CDC42BPB PE=1 SV=2"	"0.000"	""	"16"	"22"	"31"	"18"	"1711"	"194.2"	"6.37"	"4651.15"	"58.09"	"13"	"17"	"cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00130, Pf00780, Pf08826, Pf15796"	"9578"	"ENSG00000198752"	"CDC42BPB"	"A9JR72; hsa:9578; Q2L7A5; Q86TJ1; Q9ULU5; Q9Y5S2"	"CDC42 GTPase cycle; RHOQ GTPase cycle; RHOJ GTPase cycle"	"VEGFA-VEGFR2 signaling; 15q11q13 copy number variation"	"5"	"0"	"354.4"	"144.3"	"311.3"	"275.7"	"337.3"	"330.9"	"279.6"	"482.8"	"694.1"	"2657.2"	"5127.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P31942"	"Heterogeneous nuclear ribonucleoprotein H3 OS=Homo sapiens OX=9606 GN=HNRNPH3 PE=1 SV=2"	"0.000"	""	"20"	"8"	"29"	"7"	"346"	"36.9"	"6.87"	"4824.14"	"57.60"	"6"	"8"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00076"	"3189"	"ENSG00000096746"	"HNRNPH3"	"A8K682; B3KRE1; hsa:3189; P31942; Q9BSX1; Q9NP53; Q9NP96; Q9NPA7; Q9NPI4; Q9UFU4; Q9Y4J5"	""	""	"0"	"0"	"1457.7"	"316.9"	"790.5"	"550.0"	"725.3"	"775.6"	"644.8"	"793.9"	"762.4"	"1266.6"	"1881.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UHX1"	"Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1"	"0.000"	""	"27"	"15"	"29"	"15"	"559"	"59.8"	"5.29"	"4552.77"	"57.31"	"12"	"13"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"22827"	"ENSG00000179950; ENSG00000274081"	"PUF60"	"A8K8K8; hsa:22827; Q969E7; Q96D94; Q96H63; Q99628; Q9NZA0; Q9UHX1; Q9UJY7"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"2960.7"	"1100.0"	"2352.2"	"1965.3"	"2253.0"	"2685.3"	"2130.2"	"3024.8"	"2331.2"	"4068.9"	"7708.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01105"	"Protein SET OS=Homo sapiens OX=9606 GN=SET PE=1 SV=3"	"0.000"	""	"29"	"8"	"29"	"8"	"290"	"33.5"	"4.32"	"5009.68"	"57.21"	"7"	"7"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00956"	"6418"	"ENSG00000119335"	"SET"	"A5A5H4; A6NGV1; B4DUE2; hsa:6418; Q01105; Q15541; Q5VXV1; Q5VXV2; Q6FHZ5"	"HuR (ELAVL1) binds and stabilizes mRNA; Condensation of Prophase Chromosomes"	"Histone modifications; VEGFA-VEGFR2 signaling"	"4"	"0"	"2351.8"	"1285.6"	"2501.3"	"1991.2"	"2358.3"	"2876.2"	"2367.6"	"2859.9"	"2106.9"	"3017.7"	"4450.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13010"	"X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3"	"0.000"	""	"23"	"15"	"31"	"15"	"732"	"82.7"	"5.81"	"4967.95"	"57.12"	"12"	"12"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf02735, Pf03730, Pf03731, Pf08785"	"7520"	"ENSG00000079246"	"XRCC5"	"A8K3X5; hsa:7520; P13010; Q0Z7V0; Q4VBQ5; Q53HH7; Q7M4N0; Q9UCQ0; Q9UCQ1"	"Neutrophil degranulation; Cytosolic sensors of pathogen-associated DNA ; Nonhomologous End-Joining (NHEJ); 2-LTR circle formation; IRF3-mediated induction of type I IFN"	"Non-homologous end joining; Male infertility; DNA repair pathways, full network; p53 transcriptional gene network"	"9"	"0"	"1709.9"	"718.8"	"1688.3"	"1639.2"	"1650.9"	"2013.6"	"1320.8"	"1573.4"	"1005.9"	"2105.9"	"3632.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q04837"	"Single-stranded DNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SSBP1 PE=1 SV=1"	"0.000"	""	"57"	"11"	"30"	"11"	"148"	"17.2"	"9.60"	"4934.20"	"56.48"	"9"	"10"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00436"	"6742"	"ENSG00000106028; ENSG00000262771"	"SSBP1"	"hsa:6742; Q04837"	"Transcriptional activation of mitochondrial biogenesis"	""	"1"	"0"	"2472.6"	"1292.9"	"2334.9"	"2078.1"	"2180.8"	"2672.9"	"2291.7"	"2730.9"	"2332.4"	"3396.1"	"4504.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43852"	"Calumenin OS=Homo sapiens OX=9606 GN=CALU PE=1 SV=2"	"0.000"	""	"43"	"13"	"29"	"13"	"315"	"37.1"	"4.64"	"5065.47"	"55.91"	"13"	"12"	""	"non-structural extracellular;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf13833"	"813"	"ENSG00000128595"	"CALU"	"B3KPG9; D6QS48; D6QS49; D6QS50; D6QS51; D6QS52; D6QS53; D6QS54; D6QS55; D6QS56; D6QS57; D6QS58; D6QS59; F5H1Q9; F5H879; hsa:813; O43852; O60456; Q6FHB9; Q96RL3; Q9NR43"	"Platelet degranulation ; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation"	"NOTCH1 regulation of endothelial cell calcification; VEGFA-VEGFR2 signaling"	"5"	"0"	"1302.4"	"746.5"	"1513.3"	"1347.7"	"1424.9"	"1704.7"	"1168.3"	"1494.9"	"1180.6"	"2087.3"	"3620.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EK5"	"KIF-binding protein OS=Homo sapiens OX=9606 GN=KIFBP PE=1 SV=1"	"0.000"	""	"23"	"11"	"25"	"11"	"621"	"71.8"	"5.49"	"3940.01"	"55.59"	"8"	"11"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes"	"cytoskeleton;mitochondrion"	"cytoskeletal activity"	"Pf12309"	"26128"	"ENSG00000198954"	"KIFBP"	"A8K5M8; hsa:26128; Q96EK5; Q9BR89; Q9ULE1; Q9Y428"	""	""	"0"	"0"	"309.7"	"137.0"	"282.5"	"261.6"	"294.8"	"353.8"	"313.7"	"1030.4"	"2345.4"	"7128.2"	"8224.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q53GS9"	"U4/U6.U5 tri-snRNP-associated protein 2 OS=Homo sapiens OX=9606 GN=USP39 PE=1 SV=2"	"0.000"	""	"29"	"13"	"30"	"12"	"565"	"65.3"	"8.91"	"5240.45"	"55.39"	"12"	"13"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00443, Pf02148"	"10713"	"ENSG00000168883"	"USP39"	"A8K086; B3KM40; B4DHT4; D6W5L4; G5E9H0; hsa:10713; Q53GS9; Q6NX47; Q96RK9; Q9BV89; Q9H381; Q9P050; Q9Y310"	"mRNA Splicing - Major Pathway"	""	"1"	"1"	"1036.1"	"394.1"	"853.7"	"805.8"	"785.6"	"992.6"	"685.8"	"950.3"	"811.4"	"2101.6"	"3807.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60216"	"Double-strand-break repair protein rad21 homolog OS=Homo sapiens OX=9606 GN=RAD21 PE=1 SV=2"	"0.000"	""	"20"	"10"	"23"	"10"	"631"	"71.6"	"4.65"	"2978.28"	"55.15"	"6"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04824, Pf04825"	"5885"	"ENSG00000164754"	"RAD21"	"A8K0E0; hsa:5885; O60216; Q15001; Q99568"	"Meiotic synapsis; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; SUMOylation of DNA damage response and repair proteins; Estrogen-dependent gene expression; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"Cell cycle; Prion disease pathway; Regulation of sister chromatid separation at the metaphase-anaphase transition; Cohesin complex - Cornelia de Lange syndrome; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; 10q22q23 copy number variation"	"13"	"0"	"477.2"	"215.7"	"453.0"	"395.4"	"461.4"	"507.6"	"379.5"	"523.7"	"455.8"	"901.9"	"2107.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62701"	"40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2"	"0.000"	""	"44"	"13"	"38"	"13"	"263"	"29.6"	"10.15"	"6739.96"	"54.74"	"12"	"11"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00467, Pf00900, Pf01479, Pf08071, Pf16121"	"6191"	"ENSG00000198034"	"RPS4X"	"hsa:6191; P12631; P12750; P27576; P55831; P62701; Q14727; Q6IPY4"	"SRP-dependent cotranslational protein targeting to membrane; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"4147.6"	"1952.4"	"3767.2"	"3326.6"	"3353.7"	"4273.4"	"3113.6"	"3993.5"	"2744.7"	"5039.7"	"8600.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BUQ8"	"Probable ATP-dependent RNA helicase DDX23 OS=Homo sapiens OX=9606 GN=DDX23 PE=1 SV=3"	"0.000"	""	"20"	"16"	"36"	"15"	"820"	"95.5"	"9.55"	"6914.09"	"54.29"	"16"	"14"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271"	"9416"	"ENSG00000174243"	"DDX23"	"B2R600; B4DH15; hsa:9416; O43188; Q9BUQ8"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	""	"2"	"1"	"2775.0"	"1022.5"	"2053.1"	"1833.5"	"2016.3"	"2381.8"	"1617.1"	"2213.6"	"1762.9"	"3629.2"	"7435.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P78527"	"DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3"	"0.000"	""	"5"	"16"	"31"	"16"	"4128"	"468.8"	"7.12"	"5417.85"	"54.29"	"14"	"15"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00454, Pf02259, Pf02260, Pf08163, Pf19704, Pf20502"	"5591"	"ENSG00000253729"	"PRKDC"	"hsa:5591; P78527; P78528; Q13327; Q13337; Q14175; Q59H99; Q7Z611; Q96SE6; Q9UME3"	"E3 ubiquitin ligases ubiquitinate target proteins; Cytosolic sensors of pathogen-associated DNA ; Nonhomologous End-Joining (NHEJ); IRF3-mediated induction of type I IFN"	"miRNA regulation of DNA damage response; Cell cycle; Retinoblastoma gene in cancer; Fas ligand pathway and stress induction of heat shock proteins; Pathways affected in adenoid cystic carcinoma; ATM signaling in development and disease ; Non-homologous end joining; Osteoblast differentiation and related diseases; DNA repair pathways, full network; DNA damage response"	"14"	"0"	"666.4"	"252.0"	"523.7"	"432.1"	"520.8"	"547.0"	"455.7"	"748.9"	"643.7"	"1816.7"	"3613.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62081"	"40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1"	"0.000"	""	"37"	"9"	"22"	"9"	"194"	"22.1"	"10.10"	"3021.65"	"54.06"	"5"	"8"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf01251"	"6201"	"ENSG00000171863"	"RPS7"	"hsa:6201; P23821; P24818; P62081; Q57Z92; Q6IPH1"	"Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"20"	"0"	"2306.6"	"1002.1"	"1913.9"	"1661.2"	"1893.8"	"2398.4"	"1773.4"	"2279.3"	"1675.5"	"3014.7"	"4897.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13838"	"Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1"	"0.000"	""	"30"	"14"	"34"	"6"	"428"	"49.0"	"5.67"	"6090.08"	"53.77"	"14"	"13"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"7919"	"ENSG00000198563; ENSG00000215425; ENSG00000225073; ENSG00000225859; ENSG00000229496; ENSG00000230624; ENSG00000235439"	"DDX39B"	"B0S8C0; hsa:7919; O43496; Q0EFA1; Q13838; Q2L6F9; Q53GL9; Q5RJ64; Q5RJ66; Q5ST94; Q5STB4; Q5STB5; Q5STB7; Q5STB8; Q5STU4; Q5STU5; Q5STU6; Q5STU8; Q71V76"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; RHOBTB2 GTPase cycle; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	""	"5"	"7"	"2592.5"	"920.0"	"2055.8"	"1759.6"	"2158.9"	"2453.6"	"1907.7"	"2115.9"	"1989.4"	"3188.0"	"4980.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13523"	"Serine/threonine-protein kinase PRP4 homolog OS=Homo sapiens OX=9606 GN=PRPF4B PE=1 SV=3"	"0.000"	""	"14"	"14"	"33"	"13"	"1007"	"116.9"	"10.26"	"5914.72"	"53.76"	"13"	"12"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"8899"	"ENSG00000112739"	"PRPF4B"	"A8K5C9; hsa:8899; Q13523; Q5D0F6; Q5TAY8; Q8IVC3; Q8TDP2; Q96QT7; Q9UEE6"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"1"	"2305.3"	"646.3"	"1530.9"	"1320.9"	"1502.7"	"1885.9"	"1545.2"	"2403.8"	"1682.7"	"6093.6"	"9947.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61981"	"14-3-3 protein gamma OS=Homo sapiens OX=9606 GN=YWHAG PE=1 SV=2"	"0.000"	""	"47"	"11"	"34"	"6"	"247"	"28.3"	"4.89"	"5386.84"	"53.56"	"9"	"11"	"transport;signal transduction;other biological processes"	"cytosol;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00244"	"7532"	"ENSG00000170027"	"YWHAG"	"hsa:7532; O70457; P35214; P61981; Q6FH52; Q9UDP2; Q9UN99"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Regulation of localization of FOXO transcription factors; TP53 Regulates Metabolic Genes; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Activation of BAD and translocation to mitochondria"	"Cell cycle; Prolactin signaling pathway; Myometrial relaxation and contraction pathways; Disruption of postsynaptic signaling by CNV; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"21"	"0"	"477.7"	"311.9"	"446.9"	"426.3"	"425.4"	"526.4"	"462.1"	"557.4"	"563.1"	"737.8"	"1020.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43719"	"HIV Tat-specific factor 1 OS=Homo sapiens OX=9606 GN=HTATSF1 PE=1 SV=1"	"0.000"	""	"18"	"13"	"30"	"13"	"755"	"85.8"	"4.40"	"4950.83"	"53.50"	"11"	"13"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf00076"	"27336"	"ENSG00000102241"	"HTATSF1"	"D3DWG9; hsa:27336; O43719; Q59G06; Q99730"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"1690.7"	"775.2"	"1646.5"	"1461.6"	"1546.9"	"1955.7"	"1381.4"	"1813.4"	"1348.2"	"2446.0"	"4096.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94906"	"Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1"	"0.000"	""	"16"	"14"	"30"	"14"	"941"	"106.9"	"8.25"	"4989.31"	"53.49"	"13"	"13"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf06424, Pf13181"	"24148"	"ENSG00000101161"	"PRPF6"	"B2RAR5; B3KMC6; hsa:24148; O94906; O95109; Q5VXS5; Q9H3Z1; Q9H4T9; Q9H4U8; Q9NTE6"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"mRNA processing"	"3"	"0"	"1266.4"	"458.2"	"963.7"	"820.9"	"907.5"	"1048.4"	"792.9"	"1080.4"	"883.5"	"1841.3"	"3937.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96E39"	"RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1"	"0.000"	""	"24"	"8"	"34"	"3"	"390"	"42.1"	"9.89"	"6263.11"	"53.49"	"8"	"8"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf08081"	"494115"	"ENSG00000213516"	"RBMXL1"	"hsa:494115; Q96E39"	""	""	"0"	"0"	"790.4"	"172.2"	"327.9"	"259.9"	"360.5"	"371.0"	"316.7"	"438.3"	"410.9"	"837.8"	"1266.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35908"	"Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2"	"0.000"	""	"21"	"13"	"31"	"7"	"639"	"65.4"	"8.00"	"5383.71"	"53.33"	"13"	"13"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;cytosol;cytoskeleton;other cell component"	"bone, tooth or skin structural activity;cytoskeletal activity"	"Pf00038, Pf16208"	"3849"	"ENSG00000172867"	"KRT2"	"hsa:3849; P35908; Q4VAQ2"	"Formation of the cornified envelope"	""	"2"	"2"	"557.5"	"1320.8"	"778.1"	"343.4"	"1235.9"	"515.9"	"809.4"	"776.8"	"1722.2"	"1027.4"	"4559.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NC51"	"Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2"	"0.000"	""	"42"	"18"	"34"	"18"	"408"	"44.9"	"8.65"	"7804.06"	"53.02"	"15"	"12"	"cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf04774, Pf16174"	"26135"	"ENSG00000142864"	"SERBP1"	"hsa:26135; Q5VU19; Q5VU20; Q5VU22; Q8NC51; Q8WUH0; Q96SE2; Q9BTY3; Q9BUM4; Q9Y367; Q9Y4S3"	""	"Apoptosis-related network due to altered Notch3 in ovarian cancer"	"1"	"0"	"3331.8"	"1495.1"	"2987.4"	"2496.7"	"2738.2"	"3234.5"	"2255.1"	"3204.8"	"2339.6"	"4023.7"	"6045.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25705"	"ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1"	"0.000"	""	"23"	"10"	"29"	"10"	"553"	"59.7"	"9.13"	"5458.73"	"52.62"	"9"	"10"	"other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;transporter activity;other molecular function"	"Pf00006, Pf00306, Pf02874"	"498"	"ENSG00000152234"	"ATP5F1A"	"A8K092; B4DY56; hsa:498; K7ENP3; P25705; Q53XX6; Q8IXV2; Q96FB4; Q96HW2; Q96IR6; Q9BTV8"	"Mitochondrial protein import; Cristae formation; Formation of ATP by chemiosmotic coupling"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"6"	"0"	"1491.0"	"614.2"	"1032.4"	"794.0"	"1037.0"	"1071.2"	"1043.3"	"1367.8"	"1450.2"	"2834.3"	"5077.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30101"	"Protein disulfide-isomerase A3 OS=Homo sapiens OX=9606 GN=PDIA3 PE=1 SV=4"	"0.000"	""	"28"	"11"	"23"	"11"	"505"	"56.7"	"6.35"	"3586.06"	"52.33"	"9"	"10"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00085, Pf13848"	"2923"	"ENSG00000167004"	"PDIA3"	"hsa:2923; P30101; Q13453; Q14255; Q8IYF8; Q9UMU7"	"ER-Phagosome pathway; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Calnexin/calreticulin cycle"	"Prion disease pathway"	"4"	"0"	"1025.0"	"537.1"	"864.4"	"737.2"	"854.1"	"959.4"	"834.8"	"1068.9"	"1019.8"	"1603.0"	"2838.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55196"	"Afadin OS=Homo sapiens OX=9606 GN=AFDN PE=1 SV=3"	"0.000"	""	"7"	"11"	"18"	"11"	"1824"	"206.7"	"6.47"	"2525.51"	"52.22"	"4"	"11"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00498, Pf00595, Pf00788, Pf01843"	"4301"	"ENSG00000130396"	"AFDN"	"hsa:4301; O75087; O75088; O75089; P55196; Q59FP0; Q5TIG6; Q5TIG7; Q9NSN7; Q9NU92"	""	"VEGFA-VEGFR2 signaling; Ras signaling; 1q21.1 copy number variation syndrome"	"3"	"0"	"391.2"	"162.8"	"311.2"	"257.4"	"313.6"	"351.5"	"305.1"	"431.7"	"544.1"	"3303.3"	"7129.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62736"	"Actin, aortic smooth muscle OS=Homo sapiens OX=9606 GN=ACTA2 PE=1 SV=1"	"0.000"	""	"24"	"10"	"34"	"1"	"377"	"42.0"	"5.39"	"6406.98"	"51.83"	"10"	"9"	"developmental processes;other biological processes"	"extracellular matrix;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00022"	"59"	"ENSG00000107796"	"ACTA2"	"B2R8A4; hsa:59; P03996; P04108; P62736; Q6FI19"	"Smooth Muscle Contraction; NOTCH4 Intracellular Domain Regulates Transcription"	"Myometrial relaxation and contraction pathways; Striated muscle contraction pathway; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; 22q11.2 copy number variation syndrome; IL-18 signaling pathway; Regucalcin in proximal tubule epithelial kidney cells; Angiotensin II receptor type 1 pathway; Pleural mesothelioma; CCL18 signaling pathway; Urotensin-II-mediated signaling pathway; Markers of kidney cell lineage; Comprehensive IL-17A signaling; IL-26 signaling pathways; A network map of Macrophage-stimulating protein (MSP) signaling"	"16"	"0"	"134.5"	"40.7"	"93.9"	"71.0"	"91.3"	"88.8"	"79.8"	"92.6"	"84.4"	"160.7"	"289.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86YQ8"	"Copine-8 OS=Homo sapiens OX=9606 GN=CPNE8 PE=1 SV=2"	"0.000"	""	"27"	"13"	"28"	"12"	"564"	"63.1"	"5.96"	"5079.55"	"51.75"	"12"	"13"	"other biological processes"	"plasma membrane;other membranes"	"other molecular function"	"Pf00168, Pf07002"	"144402"	"ENSG00000139117"	"CPNE8"	"hsa:144402; Q2TB41; Q86VY2; Q86YQ8"	"RHOD GTPase cycle; CDC42 GTPase cycle; RHOQ GTPase cycle; RHOJ GTPase cycle"	""	"4"	"1"	"1274.8"	"617.9"	"1390.7"	"1288.1"	"1346.9"	"1690.5"	"1338.0"	"1502.6"	"1155.3"	"2324.6"	"3657.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61604"	"10 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPE1 PE=1 SV=2"	"0.000"	""	"80"	"12"	"28"	"12"	"102"	"10.9"	"8.92"	"5069.64"	"51.64"	"10"	"10"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"mitochondrion"	"other molecular function"	"Pf00166"	"3336"	"ENSG00000115541"	"HSPE1"	"hsa:3336; O95421; P61604; Q04984; Q53X54; Q9UDH0"	"RHOG GTPase cycle"	""	"1"	"0"	"638.3"	"297.2"	"503.6"	"482.4"	"582.1"	"693.8"	"730.0"	"1557.0"	"2867.1"	"6880.0"	"15286.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P36873"	"Serine/threonine-protein phosphatase PP1-gamma catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CC PE=1 SV=1"	"0.000"	""	"35"	"10"	"27"	"2"	"323"	"37.0"	"6.54"	"5043.29"	"51.57"	"9"	"10"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00149, Pf16891"	"5501"	"ENSG00000186298"	"PPP1CC"	"hsa:5501; P36873"	"Separation of Sister Chromatids; Triglyceride catabolism; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Circadian Clock; RAF activation; SHOC2 M1731 mutant abolishes MRAS complex function; Gain-of-function MRAS complexes activate RAF signaling; Downregulation of TGF-beta receptor signaling"	"Common pathways underlying drug addiction; Focal adhesion; Hippo-Merlin signaling dysregulation; Neuroinflammation and glutamatergic signaling"	"16"	"0"	"323.5"	"169.1"	"325.6"	"278.1"	"317.4"	"364.8"	"248.6"	"343.7"	"263.2"	"495.2"	"586.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P34932"	"Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4"	"0.000"	""	"22"	"18"	"32"	"15"	"840"	"94.3"	"5.19"	"5722.22"	"50.94"	"15"	"15"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport"	"non-structural extracellular;cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf00012"	"3308"	"ENSG00000170606"	"HSPA4"	"hsa:3308; O95756; P34932; Q2TAL4; Q9BUK9"	"Regulation of HSF1-mediated heat shock response"	"Parkin-ubiquitin proteasomal system pathway"	"2"	"3"	"2101.2"	"868.1"	"1875.5"	"1697.4"	"1989.4"	"2259.6"	"1738.0"	"2266.4"	"1776.6"	"3275.8"	"5427.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99613"	"Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1"	"0.000"	""	"13"	"10"	"24"	"10"	"913"	"105.3"	"5.68"	"4352.35"	"50.92"	"9"	"10"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf01399, Pf05470"	"8663"	"ENSG00000184110"	"EIF3C"	"A8K7Z0; B2RXG3; B4E1D5; H3BRV0; hsa:8663; O00215; Q99613; Q9BW98"	"Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"8"	"0"	"876.0"	"464.7"	"785.4"	"702.5"	"723.7"	"895.0"	"655.2"	"842.1"	"674.5"	"953.5"	"1885.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62140"	"Serine/threonine-protein phosphatase PP1-beta catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CB PE=1 SV=3"	"0.000"	""	"36"	"10"	"26"	"2"	"327"	"37.2"	"6.19"	"4712.50"	"50.80"	"8"	"10"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00149, Pf16891"	"5500"	"ENSG00000213639"	"PPP1CB"	"B2R5V4; D6W565; hsa:5500; P37140; P62140; Q5U087; Q6FG45"	"RAF activation; Circadian Clock; RHO GTPases activate CIT; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; Triglyceride catabolism; Regulation of PLK1 Activity at G2/M Transition; SHOC2 M1731 mutant abolishes MRAS complex function; Gain-of-function MRAS complexes activate RAF signaling; RHO GTPases activate PAKs; Downregulation of TGF-beta receptor signaling"	"Common pathways underlying drug addiction; Focal adhesion; Hippo-Merlin signaling dysregulation; 22q11.2 copy number variation syndrome; Airway smooth muscle cell contraction; Neuroinflammation and glutamatergic signaling; G13 signaling pathway"	"18"	"0"	"144.1"	"71.2"	"131.3"	"119.1"	"110.9"	"142.2"	"113.2"	"159.7"	"136.2"	"208.6"	"311.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50570"	"Dynamin-2 OS=Homo sapiens OX=9606 GN=DNM2 PE=1 SV=2"	"0.000"	""	"18"	"12"	"29"	"9"	"870"	"98.0"	"7.44"	"5015.83"	"50.73"	"11"	"12"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00169, Pf00350, Pf01031, Pf02212"	"1785"	"ENSG00000079805"	"DNM2"	"A8K1B6; E7EV30; E9PEQ4; hsa:1785; K7ESI9; P50570; Q5I0Y0; Q7Z5S3; Q9UPH4"	"Clathrin-mediated endocytosis; Recycling pathway of L1; MHC class II antigen presentation; Lysosome Vesicle Biogenesis; NGF-stimulated transcription; Golgi Associated Vesicle Biogenesis; Toll Like Receptor 4 (TLR4) Cascade; NOSTRIN mediated eNOS trafficking; Retrograde neurotrophin signalling; Formation of annular gap junctions"	"Synaptic vesicle pathway; Fragile X syndrome; Intracellular trafficking proteins involved in CMT neuropathy"	"14"	"2"	"689.1"	"318.2"	"551.9"	"471.1"	"581.6"	"698.3"	"698.0"	"1277.7"	"1256.8"	"3003.6"	"5724.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NBS9"	"Thioredoxin domain-containing protein 5 OS=Homo sapiens OX=9606 GN=TXNDC5 PE=1 SV=2"	"0.000"	""	"34"	"12"	"26"	"12"	"432"	"47.6"	"5.97"	"3495.39"	"50.69"	"8"	"11"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;ER/Golgi;other cytoplasmic organelle"	"other molecular function"	"Pf00085"	"81567"	"ENSG00000239264"	"TXNDC5"	"B2RDM2; hsa:81567; Q5TCQ0; Q8NBS9; Q8ND33; Q8TCT2; Q9BVH9"	"Neutrophil degranulation; Lysosome Vesicle Biogenesis; Golgi Associated Vesicle Biogenesis"	"VEGFA-VEGFR2 signaling"	"4"	"0"	"1634.7"	"870.4"	"1650.4"	"1710.4"	"1607.4"	"1938.0"	"1420.5"	"1914.4"	"1469.9"	"2441.2"	"3591.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P33992"	"DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5"	"0.000"	""	"20"	"14"	"28"	"14"	"734"	"82.2"	"8.37"	"4755.88"	"50.65"	"11"	"13"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855"	"4174"	"ENSG00000100297"	"MCM5"	"hsa:4174; O60785; P33992; Q14578; Q9BTJ4; Q9BWL8"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"Cell cycle; Ciliary landscape; G1 to S cell cycle control; DNA replication"	"10"	"0"	"1003.6"	"422.8"	"888.9"	"812.6"	"878.7"	"1130.2"	"950.9"	"1243.3"	"1129.7"	"1939.9"	"3844.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11908"	"Ribose-phosphate pyrophosphokinase 2 OS=Homo sapiens OX=9606 GN=PRPS2 PE=1 SV=2"	"0.000"	""	"37"	"10"	"26"	"2"	"318"	"34.7"	"6.61"	"4553.16"	"50.24"	"8"	"10"	"other metabolic processes;other biological processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf13793, Pf14572"	"5634"	"ENSG00000101911"	"PRPS2"	"hsa:5634; P11908; Q0VDH9; Q0VDI0; Q15245; Q2TAK7"	"5-Phosphoribose 1-diphosphate biosynthesis"	""	"1"	"0"	"58.9"	"19.3"	"60.3"	"50.7"	"57.3"	"69.2"	"54.1"	"68.7"	"72.5"	"215.7"	"467.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BSJ8"	"Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1"	"0.000"	""	"12"	"12"	"25"	"12"	"1104"	"122.8"	"5.83"	"4260.93"	"50.21"	"10"	"10"	"cell organization and biogenesis;transport"	"plasma membrane;other membranes;ER/Golgi"	"transporter activity;other molecular function"	"Pf00168, Pf17047"	"23344"	"ENSG00000139641"	"ESYT1"	"A0FGR7; A8K2S2; hsa:23344; O94848; Q6PJN4; Q9BSJ8; Q9H6J1; Q9H6W2; Q9Y416"	"RHOG GTPase cycle; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOD GTPase cycle; Glycosphingolipid metabolism; RHOF GTPase cycle"	""	"7"	"0"	"347.9"	"148.1"	"282.0"	"390.4"	"355.4"	"961.8"	"1251.2"	"2538.3"	"2210.9"	"4125.7"	"6643.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61247"	"40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2"	"0.000"	""	"50"	"15"	"36"	"15"	"264"	"29.9"	"9.73"	"6577.39"	"50.17"	"14"	"12"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01015"	"6189"	"ENSG00000145425"	"RPS3A"	"B2R4D4; D3DP05; hsa:6189; P33443; P49241; P61247"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"4346.5"	"1967.8"	"3906.8"	"3425.6"	"3654.3"	"4509.4"	"3121.1"	"4209.9"	"2812.5"	"5220.1"	"8410.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P47897"	"Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1"	"0.000"	""	"17"	"10"	"31"	"10"	"775"	"87.7"	"7.15"	"6521.18"	"50.16"	"10"	"10"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;mitochondrion;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00749, Pf03950, Pf04557, Pf04558"	"5859"	"ENSG00000172053"	"QARS1"	"B4DWJ2; hsa:5859; P47897"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation; Mitochondrial tRNA aminoacylation"	""	"3"	"0"	"598.0"	"270.8"	"641.4"	"540.6"	"563.1"	"652.2"	"433.3"	"606.9"	"503.7"	"1188.9"	"2765.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQ61"	"Telomerase RNA component interacting RNase OS=Homo sapiens OX=9606 GN=TRIR PE=1 SV=1"	"0.000"	""	"25"	"4"	"12"	"4"	"176"	"18.4"	"9.44"	"490.57"	"50.12"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes"	""	"nucleic acid binding activity;other molecular function"	""	"79002"	"ENSG00000123144"	"TRIR"	"hsa:79002; Q9BQ61"	""	""	"0"	"0"	"281.5"	"152.9"	"267.7"	"238.6"	"298.0"	"326.7"	"252.8"	"353.1"	"241.7"	"448.8"	"767.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q93009"	"Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2"	"0.000"	""	"12"	"10"	"26"	"10"	"1102"	"128.2"	"5.55"	"5762.76"	"50.06"	"9"	"9"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00443, Pf00917, Pf12436, Pf14533"	"7874"	"ENSG00000187555"	"USP7"	"A6NMY8; B7Z815; H0Y3G8; hsa:7874; Q93009"	"Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Ub-specific processing proteases; Regulation of TP53 Degradation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Regulation of PTEN localization"	"Nucleotide excision repair in xeroderma pigmentosum ; Warburg effect modulated by deubiquitinating enzymes and their substrates"	"10"	"0"	"796.2"	"380.8"	"828.4"	"726.8"	"761.4"	"938.7"	"656.9"	"980.6"	"718.5"	"1259.1"	"2368.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P15880"	"40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2"	"0.000"	""	"42"	"13"	"35"	"13"	"293"	"31.3"	"10.24"	"6828.76"	"49.84"	"13"	"11"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00333, Pf03719"	"6187"	"ENSG00000140988"	"RPS2"	"B2R5G0; D3DU82; hsa:6187; P15880; Q3MIB1"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol; RMTs methylate histone arginines; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Protein methylation; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"22"	"0"	"3350.7"	"1563.2"	"2821.8"	"2347.0"	"2588.9"	"3168.7"	"2502.8"	"3399.8"	"2816.2"	"5192.1"	"9445.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11021"	"Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2"	"0.000"	""	"25"	"14"	"31"	"12"	"654"	"72.3"	"5.16"	"5658.42"	"49.63"	"14"	"13"	"protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;nucleus;other cell component"	"translation activity;other molecular function"	"Pf00012"	"3309"	"ENSG00000044574"	"HSPA5"	"B0QZ61; hsa:3309; P11021; Q2EF78; Q9NPF1; Q9UK02"	"Regulation of HSF1-mediated heat shock response; Platelet degranulation ; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; ATF6B (ATF6-beta) activates chaperones; IRE1alpha activates chaperones; PERK regulates gene expression; ATF6 (ATF6-alpha) activates chaperone genes"	"Parkin-ubiquitin proteasomal system pathway; Apoptosis-related network due to altered Notch3 in ovarian cancer; Photodynamic therapy-induced unfolded protein response; Prion disease pathway; Unfolded protein response; Orexin receptor pathway"	"14"	"0"	"1731.9"	"802.2"	"1545.0"	"1292.6"	"1536.3"	"1768.9"	"1305.8"	"1748.7"	"1320.2"	"2438.2"	"4546.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18754"	"Regulator of chromosome condensation OS=Homo sapiens OX=9606 GN=RCC1 PE=1 SV=1"	"0.000"	""	"26"	"10"	"26"	"10"	"421"	"44.9"	"7.52"	"4820.84"	"48.82"	"9"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00415"	"1104"	"ENSG00000180198"	"RCC1"	"hsa:1104; P18754; Q16269; Q6NT97"	"Rev-mediated nuclear export of HIV RNA; Nuclear import of Rev protein; Postmitotic nuclear pore complex (NPC) reformation"	"22q11.2 copy number variation syndrome"	"4"	"0"	"1396.5"	"677.4"	"1408.0"	"1228.5"	"1272.9"	"1582.4"	"1192.3"	"1618.3"	"1295.9"	"2586.7"	"6420.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P24928"	"DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2"	"0.000"	""	"10"	"16"	"27"	"16"	"1970"	"217.0"	"7.37"	"4951.85"	"48.72"	"12"	"14"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00623, Pf04983, Pf04990, Pf04992, Pf04997, Pf04998, Pf05000, Pf05001"	"5430"	""	"POLR2A"	"A6NN93; B9EH88; hsa:5430; P24928; Q6NX41"	"Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; mRNA Splicing - Major Pathway; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"Pyrimidine metabolism; Eukaryotic transcription initiation; mRNA processing"	"44"	"0"	"1903.4"	"836.9"	"1721.9"	"1527.1"	"1614.4"	"1874.4"	"1428.1"	"1861.0"	"1474.4"	"2707.5"	"4875.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15371"	"Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1"	"0.000"	""	"24"	"11"	"22"	"11"	"548"	"63.9"	"6.05"	"3286.49"	"48.67"	"8"	"10"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf05091"	"8664"	"ENSG00000100353"	"EIF3D"	"A8MWD3; B2R7D4; B4DTF8; B4DVY1; hsa:8664; O15371; Q3MJD9; Q5M9Q6"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"Translation factors; VEGFA-VEGFR2 signaling; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"9"	"0"	"1083.8"	"405.2"	"970.8"	"835.2"	"884.4"	"1121.8"	"783.9"	"1001.2"	"765.5"	"1424.7"	"2616.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P68400"	"Casein kinase II subunit alpha OS=Homo sapiens OX=9606 GN=CSNK2A1 PE=1 SV=1"	"0.000"	""	"28"	"9"	"23"	"8"	"391"	"45.1"	"7.74"	"4193.19"	"48.57"	"6"	"9"	"cell-cell signaling;cell cycle OR cell proliferation;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1457"	"ENSG00000101266"	"CSNK2A1"	"B4DYS6; D3DVV8; hsa:1457; P19138; P20426; P68400; Q14013; Q5U065"	"Regulation of PTEN stability and activity; KEAP1-NFE2L2 pathway; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Regulation of TP53 Activity through Phosphorylation; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; WNT mediated activation of DVL; Signal transduction by L1; Receptor Mediated Mitophagy; Condensation of Prometaphase Chromosomes; Synthesis of PC"	"Alzheimer's disease and miRNA effects; TNF-alpha signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Translation inhibitors in chronically activated PDGFRA cells; Measles virus infection; Pleural mesothelioma; Alzheimer's disease"	"21"	"1"	"1072.1"	"514.0"	"1233.5"	"1173.8"	"1093.3"	"1455.4"	"1196.4"	"1570.5"	"1183.2"	"2382.4"	"3473.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13645"	"Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6"	"0.000"	""	"23"	"12"	"29"	"9"	"584"	"58.8"	"5.21"	"5286.90"	"48.52"	"11"	"10"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;cytosol;cytoskeleton;other cell component"	"bone, tooth or skin structural activity;other molecular function"	"Pf00038"	"3858"	"ENSG00000186395"	"KRT10"	"hsa:3858; P13645; Q14664; Q8N175"	"Formation of the cornified envelope"	""	"2"	"4"	"1089.3"	"1937.8"	"1998.8"	"898.5"	"3348.2"	"1116.0"	"1169.3"	"1752.6"	"3605.3"	"2232.6"	"9281.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62753"	"40S ribosomal protein S6 OS=Homo sapiens OX=9606 GN=RPS6 PE=1 SV=1"	"0.000"	""	"36"	"11"	"33"	"11"	"249"	"28.7"	"10.84"	"5957.18"	"48.28"	"11"	"9"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01092"	"6194"	"ENSG00000137154"	"RPS6"	"hsa:6194; P08227; P10660; P62753; Q4VBY7; Q8N6Z7"	"Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; SRP-dependent cotranslational protein targeting to membrane; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SARS-CoV-2 modulates host translation machinery; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; mTORC1-mediated signalling; Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol; Nuclear events stimulated by ALK signaling in cancer; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"IL-5 signaling pathway; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Follicle stimulating hormone (FSH) signaling pathway; Prolactin signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; Interleukin-11 signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Kit receptor signaling pathway; MECP2 and associated Rett syndrome; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Thermogenesis; Translation inhibitors in chronically activated PDGFRA cells; Gastrin signaling pathway; Head and neck squamous cell carcinoma; Thyroid hormones production and peripheral downstream signaling effects; Cytoplasmic ribosomal proteins; EGFR tyrosine kinase inhibitor resistance; IL-2 signaling pathway; Pleural mesothelioma; 2q37 copy number variation syndrome; A network map of Macrophage-stimulating protein (MSP) signaling; Interferon type I signaling pathways"	"47"	"0"	"3309.0"	"1486.1"	"3126.7"	"2850.1"	"2809.4"	"3480.9"	"2576.1"	"3464.9"	"2430.0"	"4446.9"	"6418.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9GZS1"	"DNA-directed RNA polymerase I subunit RPA49 OS=Homo sapiens OX=9606 GN=POLR1E PE=1 SV=3"	"0.000"	""	"22"	"10"	"21"	"10"	"419"	"47.2"	"8.94"	"2424.82"	"48.13"	"5"	"10"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf06870"	"64425"	"ENSG00000137054"	"POLR1E"	"hsa:64425; Q5VZT3; Q8NBA9; Q96L20; Q9GZS1"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"Pyrimidine metabolism; Eukaryotic transcription initiation; 2q13 copy number variation syndrome"	"8"	"0"	"499.3"	"213.0"	"450.9"	"383.1"	"437.3"	"507.7"	"411.7"	"977.2"	"2249.1"	"8142.6"	"11523.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62269"	"40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3"	"0.000"	""	"45"	"10"	"30"	"10"	"152"	"17.7"	"10.99"	"5555.10"	"47.62"	"9"	"9"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00416"	"6222"	"ENSG00000096150; ENSG00000223367; ENSG00000226225; ENSG00000231500; ENSG00000235650"	"RPS18"	"hsa:6222; P25232; P62269; Q5SUJ3; Q6IPF8"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"2717.4"	"1317.7"	"2490.5"	"2094.4"	"2399.2"	"2919.1"	"2157.1"	"2650.9"	"1968.6"	"2967.4"	"4646.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96P16"	"Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1"	"0.000"	""	"36"	"10"	"26"	"8"	"312"	"35.7"	"7.55"	"4735.51"	"46.97"	"8"	"9"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf04818, Pf16566"	"55197"	"ENSG00000141425"	"RPRD1A"	"A8KA42; B2RBA3; hsa:55197; Q7Z5G8; Q96FY9; Q96P16; Q9NVL4"	"RNA polymerase II transcribes snRNA genes"	""	"1"	"1"	"1471.9"	"640.2"	"1405.2"	"1155.1"	"1292.1"	"1659.5"	"1021.0"	"1451.1"	"1188.0"	"2256.8"	"3895.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q04917"	"14-3-3 protein eta OS=Homo sapiens OX=9606 GN=YWHAH PE=1 SV=4"	"0.000"	""	"28"	"7"	"25"	"4"	"246"	"28.2"	"4.84"	"3663.68"	"46.90"	"6"	"6"	"other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00244"	"7533"	"ENSG00000128245"	"YWHAH"	"hsa:7533; Q04917"	"TP53 Regulates Metabolic Genes; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Activation of BAD and translocation to mitochondria"	"Cell cycle; Myometrial relaxation and contraction pathways; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"11"	"0"	"664.5"	"327.3"	"605.4"	"518.4"	"575.2"	"717.1"	"573.0"	"819.2"	"673.3"	"1202.2"	"1963.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46109"	"Crk-like protein OS=Homo sapiens OX=9606 GN=CRKL PE=1 SV=1"	"0.000"	""	"41"	"10"	"24"	"10"	"303"	"33.8"	"6.74"	"3855.97"	"46.86"	"9"	"10"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00017, Pf00018, Pf07653"	"1399"	"ENSG00000099942"	"CRKL"	"A8KA44; D3DX35; hsa:1399; P46109"	"Regulation of signaling by CBL; Downstream signal transduction; Erythropoietin activates RAS; Frs2-mediated activation; MET activates RAP1 and RAC1; MET receptor recycling"	"Androgen receptor network in prostate cancer; B cell receptor signaling pathway; IL-3 signaling pathway; Kit receptor signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; MAPK signaling pathway; Chemokine signaling pathway; EGF/EGFR signaling pathway; 22q11.2 copy number variation syndrome; IL-2 signaling pathway; A network map of Macrophage-stimulating protein (MSP) signaling; Interferon type I signaling pathways; ErbB signaling pathway; T-cell receptor signaling pathway"	"21"	"0"	"876.2"	"403.2"	"914.2"	"808.5"	"804.2"	"1000.0"	"757.0"	"956.6"	"721.9"	"1274.3"	"1828.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01081"	"Splicing factor U2AF 35 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF1 PE=1 SV=3"	"0.000"	""	"35"	"7"	"20"	"7"	"240"	"27.9"	"8.81"	"2928.48"	"46.59"	"4"	"7"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00642"	"102724594; 7307"	"ENSG00000160201"	"U2AF1"	"hsa:102724594; hsa:7307; Q01081; Q701P4; Q71RF1"	"mRNA Splicing - Major Pathway; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"mRNA processing"	"5"	"0"	"775.4"	"276.7"	"582.1"	"520.9"	"530.4"	"833.2"	"720.4"	"1231.7"	"1016.9"	"1427.7"	"2242.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBU9"	"Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1"	"0.000"	""	"17"	"8"	"20"	"8"	"619"	"70.1"	"8.51"	"3154.61"	"46.59"	"7"	"8"	"other metabolic processes;transport"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf02136, Pf03943, Pf09162"	"10482"	"ENSG00000162231"	"NXF1"	"B4E269; hsa:10482; Q99799; Q9UBU9; Q9UQL2"	"Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"mRNA processing"	"5"	"0"	"811.8"	"362.1"	"769.8"	"672.6"	"737.2"	"880.3"	"616.0"	"774.8"	"621.6"	"1193.3"	"1711.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96PK6"	"RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2"	"0.000"	""	"21"	"13"	"31"	"13"	"669"	"69.4"	"9.67"	"5134.80"	"46.56"	"12"	"12"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00076"	"100526737; 10432"	"ENSG00000239306"	"RBM14"	"B0LM41; B3KMN4; D6RGD8; hsa:100526737; hsa:10432; O75932; Q2PYN1; Q53GV1; Q68DQ9; Q96PK5; Q96PK6"	"RUNX2 regulates bone development"	"Ciliary landscape"	"2"	"0"	"2571.1"	"1058.1"	"2084.6"	"1831.6"	"1961.0"	"2195.1"	"1646.5"	"2335.7"	"1733.5"	"3108.8"	"4430.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NSD9"	"Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3"	"0.000"	""	"25"	"13"	"25"	"13"	"589"	"66.1"	"6.84"	"4125.08"	"45.91"	"11"	"12"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03483, Pf03484, Pf17759, Pf18262"	"10056"	"ENSG00000116120"	"FARSB"	"B4DFM0; hsa:10056; O95708; Q4ZFX1; Q57ZJ5; Q9NSD9; Q9NZZ6"	"Cytosolic tRNA aminoacylation"	"VEGFA-VEGFR2 signaling; Amino acid metabolism"	"3"	"0"	"1745.7"	"724.2"	"1585.5"	"1261.1"	"1505.5"	"1788.2"	"1179.6"	"1679.4"	"1261.5"	"2331.0"	"3863.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P54136"	"Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2"	"0.000"	""	"18"	"7"	"15"	"7"	"660"	"75.3"	"6.68"	"3227.06"	"45.70"	"3"	"7"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00750, Pf03485, Pf05746"	"5917"	"ENSG00000113643"	"RARS1"	"B2RBS9; hsa:5917; P54136; Q53GY4; Q9BWA1"	"Cytosolic tRNA aminoacylation; Selenoamino acid metabolism"	"Amino acid metabolism"	"3"	"0"	"229.3"	"86.0"	"179.5"	"145.9"	"185.2"	"194.5"	"150.5"	"198.9"	"213.0"	"894.6"	"3775.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L014"	"Probable ATP-dependent RNA helicase DDX46 OS=Homo sapiens OX=9606 GN=DDX46 PE=1 SV=2"	"0.000"	""	"13"	"13"	"28"	"13"	"1031"	"117.3"	"9.29"	"5597.70"	"45.48"	"13"	"12"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"other membranes;nucleus"	"other molecular function"	"Pf00270, Pf00271"	"9879"	"ENSG00000145833"	"DDX46"	"hsa:9879; O94894; Q7L014; Q96EI0; Q9Y658"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"2302.1"	"778.8"	"1751.2"	"1436.3"	"1730.3"	"2021.6"	"1553.0"	"2186.0"	"1614.5"	"3111.4"	"7392.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35232"	"Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1"	"0.000"	""	"41"	"11"	"24"	"11"	"272"	"29.8"	"5.76"	"4430.41"	"45.45"	"9"	"11"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01145"	"5245"	"ENSG00000167085"	"PHB1"	"B4DY47; hsa:5245; P35232; Q4VBQ0"	"RAF activation; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Processing of SMDT1"	""	"5"	"0"	"1610.1"	"506.7"	"1016.2"	"796.4"	"1078.2"	"1091.3"	"878.8"	"1250.6"	"1167.0"	"2058.2"	"3853.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y606"	"tRNA pseudouridine synthase A OS=Homo sapiens OX=9606 GN=PUS1 PE=1 SV=3"	"0.000"	""	"29"	"10"	"20"	"10"	"427"	"47.4"	"8.41"	"2652.32"	"45.38"	"7"	"10"	"RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01416"	"80324"	"ENSG00000177192"	"PUS1"	"A8K877; B3KQC1; hsa:80324; Q8WYT2; Q9BU44; Q9Y606"	""	""	"0"	"0"	"281.4"	"128.7"	"242.7"	"218.3"	"261.6"	"326.0"	"263.5"	"398.5"	"600.2"	"4025.8"	"8194.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11387"	"DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2"	"0.000"	""	"16"	"10"	"28"	"10"	"765"	"90.7"	"9.31"	"4281.61"	"45.00"	"9"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf01028, Pf02919, Pf14370"	"7150"	"ENSG00000198900"	"TOP1"	"A8KA78; E1P5W3; hsa:7150; O43256; P11387; Q12855; Q12856; Q15610; Q5TFY3; Q9UJN0"	"SUMOylation of DNA replication proteins"	"Ebola virus infection in host; 15q25 copy number variation"	"3"	"0"	"624.4"	"309.0"	"557.9"	"474.3"	"496.2"	"601.3"	"455.7"	"659.4"	"765.5"	"3224.7"	"5041.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26641"	"Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3"	"0.000"	""	"21"	"12"	"32"	"12"	"437"	"50.1"	"6.67"	"5418.14"	"44.88"	"11"	"11"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity"	"Pf00043, Pf00647, Pf02798"	"1937"	"ENSG00000254772"	"EEF1G"	"B4DTG2; hsa:1937; P26641; Q6PJ62; Q6PK31; Q96CU2; Q9P196"	"Signaling by ALK fusions and activated point mutants; Eukaryotic Translation Elongation"	"Translation factors"	"3"	"0"	"2404.8"	"1111.6"	"2658.3"	"2498.3"	"2462.4"	"3237.7"	"2281.3"	"2908.1"	"2264.3"	"4062.1"	"6342.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14980"	"Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2"	"0.000"	""	"8"	"15"	"25"	"15"	"2115"	"238.1"	"5.78"	"4513.37"	"44.84"	"13"	"12"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	""	"4926"	"ENSG00000137497"	"NUMA1"	"H0YH75; hsa:4926; Q14980; Q14981; Q9BTE9"	"Recruitment of NuMA to mitotic centrosomes; Mitotic Prophase"	"Ectoderm differentiation; Ectoderm differentiation; 8p23.1 copy number variation syndrome"	"5"	"0"	"1080.3"	"374.4"	"754.5"	"632.7"	"749.6"	"783.2"	"604.5"	"806.6"	"679.8"	"1257.1"	"1933.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11171"	"Protein 4.1 OS=Homo sapiens OX=9606 GN=EPB41 PE=1 SV=4"	"0.000"	""	"15"	"13"	"27"	"11"	"864"	"97.0"	"5.58"	"4884.00"	"44.74"	"13"	"11"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf04382, Pf05902, Pf08736, Pf09379, Pf09380"	"2035"	"ENSG00000159023"	"EPB41"	"B1ALH8; B1ALH9; D3DPM9; D3DPN0; hsa:2035; P11171; P11176; Q14245; Q5TB35; Q5VXN8; Q8IXV9; Q9Y578; Q9Y579"	"Neurexins and neuroligins"	"VEGFA-VEGFR2 signaling; Splicing factor NOVA regulated synaptic proteins; IL-18 signaling pathway"	"4"	"0"	"730.9"	"325.2"	"642.5"	"597.4"	"686.9"	"818.8"	"634.3"	"1011.8"	"1366.6"	"5781.8"	"6792.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55265"	"Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4"	"0.000"	""	"11"	"11"	"27"	"11"	"1226"	"136.0"	"8.65"	"4675.63"	"44.70"	"9"	"9"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00035, Pf02137, Pf02295"	"103"	"ENSG00000160710"	"ADAR"	"B1AQQ9; B1AQR0; D3DV76; hsa:103; O15223; O43859; O43860; P55265; Q9BYM3; Q9BYM4"	"Interferon alpha/beta signaling; C6 deamination of adenosine; Formation of editosomes by ADAR proteins"	"Measles virus infection; Cytosolic DNA-sensing pathway"	"5"	"0"	"2400.2"	"636.2"	"1447.2"	"1205.2"	"1428.8"	"1616.7"	"1108.0"	"1555.1"	"1245.3"	"2197.8"	"3756.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P1J9"	"Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1"	"0.000"	""	"29"	"15"	"30"	"15"	"531"	"60.5"	"9.61"	"4543.52"	"44.51"	"13"	"15"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf05179, Pf16050"	"79577"	"ENSG00000134371"	"CDC73"	"A6NLZ8; B2RBR2; hsa:79577; Q6P1J9; Q6PK51; Q96A07; Q9H245; Q9H5L7"	"Hedgehog 'on' state; E3 ubiquitin ligases ubiquitinate target proteins; Formation of the beta-catenin:TCF transactivating complex; Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events"	"Endoderm differentiation"	"7"	"0"	"2423.7"	"1163.4"	"2286.9"	"1980.4"	"2154.2"	"2540.7"	"1866.2"	"2456.1"	"1817.7"	"3585.7"	"5991.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18124"	"60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1"	"0.000"	""	"33"	"9"	"28"	"9"	"248"	"29.2"	"10.65"	"5037.55"	"44.31"	"9"	"9"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00327, Pf08079"	"6129"	"ENSG00000147604"	"RPL7"	"A8K504; hsa:6129; P18124; Q15289; Q3KQU0; Q5I0X1; Q6IBM9"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"15"	"0"	"935.5"	"377.1"	"847.6"	"698.4"	"768.8"	"934.8"	"724.2"	"942.4"	"763.6"	"1323.8"	"1972.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q07021"	"Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1"	"0.000"	""	"32"	"6"	"21"	"6"	"282"	"31.3"	"4.84"	"3597.49"	"44.15"	"5"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;translation activity;nucleic acid binding activity;other molecular function"	"Pf02330"	"708"	"ENSG00000108561"	"C1QBP"	"hsa:708; Q07021; Q2HXR8; Q9NNY8"	"RHOC GTPase cycle; RHOA GTPase cycle; Intrinsic Pathway of Fibrin Clot Formation; Apoptotic factor-mediated response; Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function"	"Complement system; Mesodermal commitment pathway; Ebola virus infection in host"	"8"	"0"	"1018.2"	"560.6"	"1011.3"	"867.2"	"1005.5"	"1091.0"	"909.7"	"1052.1"	"937.6"	"1434.4"	"2020.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50990"	"T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4"	"0.000"	""	"18"	"9"	"22"	"9"	"548"	"59.6"	"5.60"	"4506.27"	"44.11"	"9"	"8"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00118"	"10694"	"ENSG00000156261"	"CCT8"	"A6NN54; B4DEM7; B4DQH4; hsa:10694; P50990; Q4VBP8"	"Neutrophil degranulation; Association of TriC/CCT with target proteins during biosynthesis; Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"16p11.2 proximal deletion syndrome"	"8"	"0"	"1537.9"	"631.2"	"1152.0"	"935.2"	"1126.1"	"1289.7"	"986.2"	"1267.3"	"999.0"	"2108.9"	"4917.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46013"	"Proliferation marker protein Ki-67 OS=Homo sapiens OX=9606 GN=MKI67 PE=1 SV=2"	"0.000"	""	"8"	"15"	"27"	"15"	"3256"	"358.5"	"9.45"	"5457.74"	"44.07"	"15"	"12"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00498, Pf08065, Pf15276"	"4288"	"ENSG00000148773"	"MKI67"	"hsa:4288; P46013; Q5VWH2"	""	"Primary focal segmental glomerulosclerosis (FSGS)"	"1"	"0"	"1448.5"	"611.3"	"1271.3"	"1097.2"	"1190.8"	"1336.2"	"942.5"	"1430.6"	"1125.3"	"2429.7"	"4873.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q1KMD3"	"Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1"	"0.000"	""	"18"	"11"	"21"	"11"	"747"	"85.1"	"4.91"	"2925.74"	"44.02"	"9"	"11"	""	"nucleus;other cell component"	""	"Pf00622, Pf02037, Pf13671"	"221092"	"ENSG00000214753"	"HNRNPUL2"	"hsa:221092; Q1KMD3; Q8N3B3"	""	""	"0"	"0"	"2644.8"	"725.5"	"1451.7"	"1292.9"	"1471.0"	"1654.9"	"1349.2"	"1806.8"	"1666.1"	"2346.9"	"4115.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P39687"	"Acidic leucine-rich nuclear phosphoprotein 32 family member A OS=Homo sapiens OX=9606 GN=ANP32A PE=1 SV=1"	"0.000"	""	"31"	"8"	"24"	"6"	"249"	"28.6"	"4.09"	"3705.16"	"43.69"	"6"	"7"	"transport;signal transduction;other biological processes"	"ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf14580"	"8125"	"ENSG00000140350"	"ANP32A"	"B2R6T4; hsa:8125; P39687; Q53FK4; Q5J8L8; Q7M4N6"	"HuR (ELAVL1) binds and stabilizes mRNA"	"IL-18 signaling pathway"	"2"	"3"	"2141.2"	"1453.6"	"1764.8"	"1408.2"	"1719.4"	"1986.3"	"1879.9"	"2145.2"	"2093.7"	"2404.8"	"3465.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P17987"	"T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1"	"0.000"	""	"28"	"12"	"23"	"12"	"556"	"60.3"	"6.11"	"4858.57"	"43.34"	"11"	"10"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf00118"	"6950"	"ENSG00000120438"	"TCP1"	"E1P5B2; hsa:6950; P17987; Q15556; Q5TCM3"	"Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"16p11.2 proximal deletion syndrome"	"8"	"0"	"1354.7"	"517.4"	"1109.1"	"919.7"	"1118.2"	"1231.5"	"913.8"	"1167.2"	"1001.6"	"2173.9"	"4476.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09012"	"U1 small nuclear ribonucleoprotein A OS=Homo sapiens OX=9606 GN=SNRPA PE=1 SV=3"	"0.000"	""	"23"	"6"	"28"	"4"	"282"	"31.3"	"9.83"	"4165.96"	"43.20"	"5"	"6"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6626"	"ENSG00000077312"	"SNRPA"	"hsa:6626; P09012"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"4"	"6260.1"	"1954.6"	"3733.7"	"2799.5"	"3960.2"	"4095.9"	"2868.1"	"4264.0"	"3587.5"	"5468.8"	"7562.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30876"	"DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1"	"0.000"	""	"14"	"15"	"29"	"15"	"1174"	"133.8"	"6.87"	"5999.99"	"43.15"	"15"	"12"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00562, Pf04560, Pf04561, Pf04563, Pf04565, Pf04566, Pf04567"	"5431"	"ENSG00000047315"	"POLR2B"	"A8K1A8; hsa:5431; P30876; Q8IZ61"	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; mRNA Splicing - Major Pathway; PIWI-interacting RNA (piRNA) biogenesis; mRNA Splicing - Minor Pathway; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"Pyrimidine metabolism; Eukaryotic transcription initiation"	"43"	"0"	"1632.7"	"731.4"	"1554.7"	"1338.6"	"1482.1"	"1770.4"	"1315.7"	"1614.3"	"1355.4"	"2665.6"	"4245.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5X1"	"Sorting nexin-9 OS=Homo sapiens OX=9606 GN=SNX9 PE=1 SV=1"	"0.000"	""	"17"	"10"	"24"	"10"	"595"	"66.6"	"5.58"	"4853.48"	"42.76"	"9"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf00018, Pf00787, Pf10456"	"51429"	"ENSG00000130340"	"SNX9"	"hsa:51429; Q9BSI7; Q9BVM1; Q9UJH6; Q9UP20; Q9Y5X1"	"Clathrin-mediated endocytosis; Golgi Associated Vesicle Biogenesis"	""	"2"	"0"	"404.2"	"180.6"	"382.6"	"391.4"	"418.7"	"858.2"	"1236.9"	"2664.5"	"2404.7"	"5100.9"	"5109.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q06830"	"Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1"	"0.000"	""	"48"	"10"	"28"	"9"	"199"	"22.1"	"8.13"	"4975.98"	"42.39"	"10"	"9"	"cell cycle OR cell proliferation;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00578, Pf10417"	"5052"	"ENSG00000117450"	"PRDX1"	"B5BU26; D3DPZ8; hsa:5052; P35703; Q06830; Q2V576; Q5T154; Q5T155"	"Detoxification of Reactive Oxygen Species; TP53 Regulates Metabolic Genes; NFE2L2 regulating anti-oxidant/detoxification enzymes; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"	"Androgen receptor signaling pathway; Selenium micronutrient network; Nuclear receptors meta-pathway; NRF2 pathway"	"8"	"1"	"1889.3"	"919.4"	"1409.1"	"1196.5"	"1432.7"	"1546.4"	"1387.9"	"1564.5"	"1603.4"	"2169.7"	"3619.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11586"	"C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=3"	"0.000"	""	"16"	"11"	"22"	"11"	"935"	"101.5"	"7.30"	"3743.89"	"42.17"	"10"	"11"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"887.9"	"435.2"	"811.3"	"664.6"	"750.7"	"872.5"	"615.8"	"797.7"	"666.2"	"1149.3"	"1643.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2L1"	"Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2"	"0.000"	""	"18"	"14"	"23"	"14"	"958"	"108.9"	"7.14"	"4413.85"	"41.84"	"12"	"11"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00773, Pf13638, Pf17215, Pf17216, Pf17849"	"22894"	"ENSG00000083520"	"DIS3"	"A6NI21; B2RBL2; hsa:22894; Q5W0P7; Q5W0P8; Q658Z7; Q7Z481; Q8WWI2; Q9UG36; Q9Y2L1"	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	""	"6"	"0"	"1101.3"	"502.6"	"997.4"	"811.4"	"951.7"	"1129.6"	"870.8"	"1104.2"	"884.5"	"1922.4"	"5894.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15283"	"Ras GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=RASA2 PE=1 SV=3"	"0.000"	""	"16"	"13"	"29"	"13"	"850"	"96.6"	"7.20"	"4876.63"	"41.61"	"13"	"12"	"signal transduction;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00168, Pf00169, Pf00616, Pf00779"	"5922"	"ENSG00000155903"	"RASA2"	"A8K7K1; G3V0F9; hsa:5922; O00695; Q15283; Q15284; Q92594; Q99577; Q9UEQ2"	"Regulation of RAS by GAPs"	"MAPK signaling pathway; Ebola virus infection in host; Ras signaling; Modulators of TCR signaling and T cell activation"	"5"	"0"	"663.8"	"286.3"	"601.0"	"599.3"	"589.5"	"871.6"	"1109.7"	"3276.1"	"3455.3"	"7081.2"	"6344.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63244"	"Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3"	"0.000"	""	"32"	"11"	"28"	"11"	"317"	"35.1"	"7.69"	"4149.57"	"41.53"	"11"	"11"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;cytosol;mitochondrion;translational apparatus;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;translation activity;other molecular function"	"Pf00400"	"10399"	"ENSG00000204628"	"RACK1"	"B3KTJ0; D3DWS0; hsa:10399; P25388; P63244; P99049; Q53HU2; Q5J8M6; Q5VLR4; Q6FH47"	"Regulation of TNFR1 signaling; TNFR1-induced NF-kappa-B signaling pathway; TNFR1-mediated ceramide production"	"Androgen receptor signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; VEGFA-VEGFR2 signaling; Measles virus infection; Angiotensin II receptor type 1 pathway; TROP2 regulatory signaling; Interferon type I signaling pathways"	"10"	"0"	"2107.2"	"759.0"	"1624.5"	"1367.1"	"1606.7"	"1896.1"	"1381.0"	"2055.0"	"1592.5"	"3326.9"	"6284.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15365"	"Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2"	"0.000"	""	"32"	"9"	"21"	"4"	"356"	"37.5"	"7.09"	"3991.83"	"41.46"	"8"	"9"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013"	"5093"	"ENSG00000169564"	"PCBP1"	"hsa:5093; Q13157; Q14975; Q15365"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"Ferroptosis"	"3"	"6"	"1940.3"	"740.9"	"1948.0"	"1560.7"	"1713.4"	"2025.2"	"1389.9"	"1910.6"	"1516.8"	"2863.0"	"3826.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27348"	"14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1"	"0.000"	""	"34"	"7"	"25"	"4"	"245"	"27.7"	"4.78"	"4461.83"	"41.39"	"7"	"7"	"transport;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00244"	"10971"	"ENSG00000134308"	"YWHAQ"	"D6W4Z5; hsa:10971; P27348; Q567U5; Q5TZU8; Q9UP48"	"TP53 Regulates Metabolic Genes; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Regulation of localization of FOXO transcription factors; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Activation of BAD and translocation to mitochondria"	"Cell cycle; Pathogenic Escherichia coli infection; Primary focal segmental glomerulosclerosis (FSGS); IL-3 signaling pathway; Myometrial relaxation and contraction pathways; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-YAP signaling; Leukocyte-intrinsic Hippo pathway functions; Hepatitis B infection; Opioid receptor pathways; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"20"	"0"	"414.8"	"166.3"	"392.5"	"392.8"	"369.4"	"494.8"	"357.5"	"429.0"	"292.3"	"453.5"	"782.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15366"	"Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1"	"0.000"	""	"25"	"8"	"22"	"2"	"365"	"38.6"	"6.79"	"4569.14"	"41.31"	"8"	"8"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013"	"5094"	"ENSG00000197111"	"PCBP2"	"A8K7X6; B4DXP5; F8VYL7; G3V0E8; hsa:5094; I6L8F9; Q15366; Q32Q82; Q59HD4; Q68Y55; Q6IPF4; Q6PKG5"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA; Negative regulators of DDX58/IFIH1 signaling; SARS-CoV-1 activates/modulates innate immune responses"	"mRNA processing; Ferroptosis; Modulators of TCR signaling and T cell activation"	"7"	"1"	"953.7"	"380.4"	"921.9"	"650.2"	"753.5"	"914.0"	"673.4"	"912.4"	"818.3"	"1274.4"	"1773.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P00367"	"Glutamate dehydrogenase 1, mitochondrial OS=Homo sapiens OX=9606 GN=GLUD1 PE=1 SV=2"	"0.000"	""	"20"	"11"	"20"	"11"	"558"	"61.4"	"7.80"	"2368.68"	"41.07"	"6"	"10"	"other metabolic processes;other biological processes"	"mitochondrion;ER/Golgi;other cell component"	"other molecular function"	"Pf00208, Pf02812"	"2746"	"ENSG00000148672"	"GLUD1"	"B3KV55; B4DGN5; hsa:2746; P00367; Q5TBU3"	"Transcriptional activation of mitochondrial biogenesis; Glutamate and glutamine metabolism"	"VEGFA-VEGFR2 signaling; Amino acid metabolism; Metabolic reprogramming in colon cancer; 22q11.2 copy number variation syndrome; Amino acid metabolism pathway excerpt: histidine catabolism extension; 10q22q23 copy number variation"	"8"	"0"	"1679.2"	"926.6"	"1582.2"	"1331.6"	"1547.2"	"1935.3"	"1458.1"	"1934.9"	"1662.0"	"3251.3"	"6825.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N7H5"	"RNA polymerase II-associated factor 1 homolog OS=Homo sapiens OX=9606 GN=PAF1 PE=1 SV=2"	"0.000"	""	"24"	"11"	"24"	"11"	"531"	"59.9"	"4.63"	"4186.84"	"40.72"	"11"	"11"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf03985"	"54623"	"ENSG00000006712"	"PAF1"	"hsa:54623; M0QX35; O75239; Q8N7H5; Q9H166; Q9NUU9"	"RNA Polymerase II Pre-transcription Events; E3 ubiquitin ligases ubiquitinate target proteins; Formation of RNA Pol II elongation complex"	"Endoderm differentiation"	"5"	"0"	"1294.4"	"554.9"	"1314.7"	"1118.6"	"1266.8"	"1492.5"	"1020.0"	"1436.5"	"1019.5"	"2209.2"	"3575.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P57772"	"Selenocysteine-specific elongation factor OS=Homo sapiens OX=9606 GN=EEFSEC PE=1 SV=4"	"0.000"	""	"14"	"8"	"23"	"8"	"596"	"65.3"	"8.35"	"3592.93"	"40.71"	"8"	"8"	"protein metabolism;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009"	"60678"	"ENSG00000132394; ENSG00000284869"	"EEFSEC"	"hsa:60678; P57772; Q96HZ6"	"Selenocysteine synthesis"	""	"1"	"0"	"335.6"	"140.7"	"286.9"	"251.0"	"291.5"	"332.1"	"376.4"	"1126.7"	"1850.0"	"3755.3"	"3597.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WUM0"	"Nuclear pore complex protein Nup133 OS=Homo sapiens OX=9606 GN=NUP133 PE=1 SV=2"	"0.000"	""	"11"	"12"	"25"	"12"	"1156"	"128.9"	"5.10"	"3855.80"	"40.67"	"11"	"12"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf03177"	"55746"	"ENSG00000069248"	"NUP133"	"B2RAZ8; hsa:55746; Q5T8N0; Q8WUM0; Q9H9W2; Q9NV71; Q9NVC4"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; SUMOylation of DNA replication proteins; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; SARS-CoV-2 activates/modulates innate and adaptive immune responses; snRNP Assembly; HCMV Early Events; SUMOylation of DNA damage response and repair proteins; HCMV Late Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; Postmitotic nuclear pore complex (NPC) reformation"	"Ciliary landscape"	"36"	"0"	"1747.2"	"751.7"	"1847.8"	"1551.8"	"1641.6"	"1923.2"	"1356.2"	"1711.3"	"1296.7"	"2163.2"	"3705.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22234"	"Multifunctional protein ADE2 OS=Homo sapiens OX=9606 GN=PAICS PE=1 SV=3"	"0.000"	""	"24"	"8"	"25"	"8"	"425"	"47.0"	"7.23"	"4313.59"	"40.59"	"7"	"8"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00731, Pf01259"	"10606"	"ENSG00000128050"	"PAICS"	"E9PDH9; hsa:10606; P22234; Q68CQ5"	"Purine ribonucleoside monophosphate biosynthesis"	"Metabolic reprogramming in colon cancer"	"2"	"0"	"616.3"	"246.7"	"520.5"	"444.2"	"509.5"	"557.3"	"462.2"	"601.8"	"527.1"	"1106.2"	"3796.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y237"	"Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 OS=Homo sapiens OX=9606 GN=PIN4 PE=1 SV=1"	"0.000"	""	"61"	"8"	"20"	"8"	"131"	"13.8"	"9.77"	"2507.42"	"40.27"	"6"	"8"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13616"	"5303"	"ENSG00000102309"	"PIN4"	"A8E0G6; B3KXM0; F5H1P5; hsa:5303; Q0D2H3; Q3MHV0; Q52M21; Q5HYW6; Q6IRW4; Q9Y237"	""	""	"0"	"0"	"1133.5"	"721.7"	"1210.2"	"1040.4"	"1202.5"	"1485.6"	"1148.5"	"1403.4"	"1212.3"	"2447.9"	"2594.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00267"	"Transcription elongation factor SPT5 OS=Homo sapiens OX=9606 GN=SUPT5H PE=1 SV=1"	"0.000"	""	"12"	"13"	"24"	"13"	"1087"	"120.9"	"5.06"	"4995.31"	"40.09"	"12"	"10"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00467, Pf03439, Pf11942"	"6829"	"ENSG00000196235"	"SUPT5H"	"hsa:6829; O00267; O43279; Q59G52; Q99639"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE"	"Initiation of transcription and translation elongation at the HIV-1 LTR; mRNA processing"	"20"	"0"	"2144.8"	"878.8"	"1932.6"	"1758.9"	"1862.3"	"2245.3"	"1738.5"	"2441.9"	"1715.6"	"3155.6"	"5179.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P80723"	"Brain acid soluble protein 1 OS=Homo sapiens OX=9606 GN=BASP1 PE=1 SV=2"	"0.000"	""	"52"	"9"	"23"	"9"	"227"	"22.7"	"4.63"	"5533.98"	"40.07"	"8"	"8"	"developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05466"	"10409"	"ENSG00000176788"	"BASP1"	"B4DJA8; D3DTD5; hsa:10409; O43596; P80723; Q5U0S0; Q9BWA5"	"RHOF GTPase cycle"	""	"1"	"0"	"1581.2"	"656.3"	"1531.3"	"1404.4"	"1429.5"	"1794.9"	"1263.3"	"1558.2"	"1078.3"	"1865.8"	"3444.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62826"	"GTP-binding nuclear protein Ran OS=Homo sapiens OX=9606 GN=RAN PE=1 SV=3"	"0.000"	""	"40"	"7"	"19"	"7"	"216"	"24.4"	"7.49"	"2773.80"	"40.02"	"6"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00071"	"5901"	"ENSG00000132341"	"RAN"	"A8K3Z8; hsa:5901; P17080; P28746; P28747; P62826; Q6IPB2; Q86V08; Q8NI90; Q9CSP3; Q9CWI7; Q9CZA2; Q9UDJ5; Q9UEU9"	"Rev-mediated nuclear export of HIV RNA; NEP/NS2 Interacts with the Cellular Export Machinery; Nuclear import of Rev protein; Transcriptional regulation by small RNAs; tRNA processing in the nucleus; Regulation of cholesterol biosynthesis by SREBP (SREBF); MicroRNA (miRNA) biogenesis; Postmitotic nuclear pore complex (NPC) reformation"	"Androgen receptor signaling pathway; miRNA biogenesis; 22q11.2 copy number variation syndrome"	"11"	"0"	"1036.9"	"711.3"	"1028.7"	"958.4"	"935.7"	"1141.8"	"1055.5"	"1214.6"	"1288.9"	"1906.4"	"3081.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P01116"	"GTPase KRas OS=Homo sapiens OX=9606 GN=KRAS PE=1 SV=1"	"0.000"	""	"41"	"5"	"19"	"5"	"189"	"21.6"	"6.77"	"3264.11"	"39.92"	"4"	"5"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00071"	"3845"	"ENSG00000133703"	"KRAS"	"A8K8Z5; B0LPF9; hsa:3845; P01116; P01118; Q96D10"	"Signaling by CSF3 (G-CSF); Signaling by CSF1 (M-CSF) in myeloid cells; RAS processing; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAS GAP mutants; Signaling by RAS GTPase mutants; RUNX3 regulates p14-ARF"	"IL-5 signaling pathway; Alzheimer's disease and miRNA effects; Glioblastoma signaling pathways; RalA downstream regulated genes; TNF-alpha signaling pathway; Oncostatin M signaling pathway; Aryl hydrocarbon receptor pathway; Bladder cancer; Extracellular vesicle-mediated signaling in recipient cells; RAC1/PAK1/p38/MMP2 pathway; G protein signaling pathways; BDNF-TrkB signaling; MAPK signaling pathway; PI3K-AKT-mTOR signaling pathway and therapeutic opportunities in prostate cancer; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Endometrial cancer; PI3K-Akt signaling pathway; Chromosomal and microsatellite instability in colorectal cancer ; MAPK cascade; Ras signaling; Epithelial to mesenchymal transition in colorectal cancer; Non-small cell lung cancer; Breast cancer pathway; Pancreatic adenocarcinoma pathway; Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells; Thermogenesis; Non-genomic actions of 1,25 dihydroxyvitamin D3; EGF/EGFR signaling pathway; Relationship between inflammation, COX-2 and EGFR; Envelope proteins and their potential roles in EDMD physiopathology; Synaptic signaling pathways associated with autism spectrum disorder; Hippo-Merlin signaling dysregulation; Fragile X syndrome; Gastrin signaling pathway; Hepatitis B infection; Head and neck squamous cell carcinoma; Melanoma; EGFR tyrosine kinase inhibitor resistance; Kisspeptin/kisspeptin receptor system in the ovary; MAPK pathway in congenital thyroid cancer; Regulation of actin cytoskeleton; Alzheimer's disease; Autophagy in pancreatic ductal adenocarcinoma; JAK-STAT signaling in the regulation of Beta-cells; ErbB signaling pathway; DNA damage response (only ATM dependent); Serotonin receptor 2 and ELK-SRF/GATA4 signaling"	"57"	"0"	"756.3"	"393.4"	"728.1"	"665.1"	"729.9"	"864.3"	"759.4"	"1074.0"	"1055.5"	"2468.0"	"4374.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15717"	"ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2"	"0.000"	""	"33"	"9"	"22"	"9"	"326"	"36.1"	"9.17"	"4143.92"	"39.56"	"9"	"9"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"1994"	"ENSG00000066044"	"ELAVL1"	"B4DVB8; hsa:1994; Q15717; Q53XN6; Q9BTT1"	"HuR (ELAVL1) binds and stabilizes mRNA"	"AMP-activated protein kinase signaling; Endoderm differentiation; Pre-implantation embryo; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Gastrin signaling pathway; IL-18 signaling pathway; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; 1p36 copy number variation syndrome"	"10"	"0"	"3041.5"	"696.4"	"1457.7"	"1132.2"	"1445.2"	"1524.7"	"1356.6"	"1611.4"	"1449.1"	"2099.7"	"3668.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P60842"	"Eukaryotic initiation factor 4A-I OS=Homo sapiens OX=9606 GN=EIF4A1 PE=1 SV=1"	"0.000"	""	"24"	"10"	"25"	"5"	"406"	"46.1"	"5.48"	"5740.40"	"39.10"	"10"	"8"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"1973"	"ENSG00000161960"	"EIF4A1"	"B2R6L8; D3DTP9; hsa:1973; J3QLC4; P04765; P60842; Q5U018; Q61516"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Deadenylation of mRNA; ISG15 antiviral mechanism"	"Translation factors; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Interferon type I signaling pathways"	"11"	"5"	"1543.4"	"770.7"	"1420.7"	"1438.8"	"1447.5"	"1850.9"	"1377.9"	"1528.7"	"1304.2"	"2032.1"	"3773.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35240"	"Merlin OS=Homo sapiens OX=9606 GN=NF2 PE=1 SV=1"	"0.000"	""	"18"	"9"	"17"	"9"	"595"	"69.6"	"6.47"	"2084.64"	"39.02"	"5"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity"	"Pf00373, Pf00769, Pf09379, Pf09380, Pf20492"	"4771"	"ENSG00000186575"	"NF2"	"hsa:4771; O95683; P35240; Q8WUJ2; Q969N0; Q969Q3; Q96T30; Q96T31; Q96T32; Q96T33; Q9BTW3; Q9UNG9; Q9UNH3; Q9UNH4"	"Regulation of actin dynamics for phagocytic cup formation; RHO GTPases activate PAKs"	"Ectoderm differentiation; Ectoderm differentiation; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-YAP signaling; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; 3q29 copy number variation syndrome; Pleural mesothelioma"	"10"	"0"	"553.2"	"243.1"	"450.1"	"347.7"	"454.9"	"504.5"	"361.8"	"534.4"	"559.5"	"4345.7"	"7540.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82979"	"SAP domain-containing ribonucleoprotein OS=Homo sapiens OX=9606 GN=SARNP PE=1 SV=3"	"0.000"	""	"25"	"7"	"24"	"7"	"210"	"23.7"	"6.42"	"3897.88"	"39.00"	"7"	"7"	"other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02037"	"84324"	"ENSG00000205323"	"SARNP"	"A8K393; hsa:84324; P82979; Q9P066"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript"	""	"3"	"0"	"1808.2"	"992.7"	"1535.4"	"1481.1"	"1639.4"	"1899.3"	"1532.5"	"1738.0"	"1493.6"	"2634.0"	"5344.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43395"	"U4/U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2"	"0.000"	""	"19"	"10"	"19"	"10"	"683"	"77.5"	"9.50"	"3350.24"	"38.98"	"8"	"9"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf01480, Pf06544, Pf08572"	"9129"	"ENSG00000117360"	"PRPF3"	"B4DSY9; hsa:9129; O43395; O43446; Q5VT54"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"0"	"1341.8"	"492.0"	"1072.5"	"907.3"	"1065.3"	"1221.0"	"861.5"	"1115.6"	"856.4"	"1677.4"	"2816.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75131"	"Copine-3 OS=Homo sapiens OX=9606 GN=CPNE3 PE=1 SV=1"	"0.000"	""	"12"	"5"	"18"	"4"	"537"	"60.1"	"5.85"	"2583.00"	"38.89"	"4"	"5"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf00168, Pf07002"	"8895"	"ENSG00000085719"	"CPNE3"	"A8KA47; hsa:8895; O75131; Q8IYA1"	"Neutrophil degranulation; Glycerophospholipid biosynthesis"	""	"2"	"0"	"742.8"	"282.4"	"527.0"	"434.8"	"542.7"	"583.6"	"549.2"	"823.9"	"892.3"	"1441.7"	"3268.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35611"	"Alpha-adducin OS=Homo sapiens OX=9606 GN=ADD1 PE=1 SV=2"	"0.000"	""	"19"	"10"	"18"	"8"	"737"	"80.9"	"5.83"	"2588.11"	"38.84"	"7"	"10"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00596"	"118"	"ENSG00000087274"	"ADD1"	"A2A3N8; A2A3P0; B4DI79; D3DVR3; D3DVR4; D3DVR5; hsa:118; P35611; Q13734; Q14729; Q16156; Q86XM2; Q9UJB6"	"XBP1(S) activates chaperone genes; Caspase-mediated cleavage of cytoskeletal proteins; Miscellaneous transport and binding events"	""	"3"	"1"	"526.8"	"232.8"	"478.7"	"408.1"	"440.1"	"537.2"	"421.9"	"667.4"	"554.4"	"1515.3"	"3902.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6UN15"	"Pre-mRNA 3'-end-processing factor FIP1 OS=Homo sapiens OX=9606 GN=FIP1L1 PE=1 SV=1"	"0.000"	""	"22"	"9"	"20"	"9"	"594"	"66.5"	"5.59"	"3961.92"	"38.40"	"7"	"8"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	""	"Pf05182"	"81608"	"ENSG00000145216"	"FIP1L1"	"B4DIR3; G3XAD6; hsa:81608; Q0VGE0; Q499Y4; Q49AU3; Q6UN15; Q7Z608; Q8WVN3; Q96F80; Q9H077"	"Transport of Mature mRNA Derived from an Intronless Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; Signaling by cytosolic PDGFRA and PDGFRB fusion proteins"	""	"6"	"0"	"992.8"	"402.6"	"872.8"	"699.1"	"791.5"	"937.7"	"696.9"	"1012.8"	"718.1"	"1575.1"	"2680.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NZW5"	"MAGUK p55 subfamily member 6 OS=Homo sapiens OX=9606 GN=MPP6 PE=1 SV=2"	"0.000"	""	"22"	"11"	"25"	"10"	"540"	"61.1"	"6.18"	"3991.26"	"38.33"	"10"	"11"	"cell organization and biogenesis"	"plasma membrane;other membranes;other cell component"	""	"Pf00595, Pf00625, Pf02828, Pf07653"	"51678"	"ENSG00000105926"	"PALS2"	"A4D157; hsa:51678; Q9H0E1; Q9NZW5"	""	""	"0"	"1"	"1146.4"	"547.6"	"976.7"	"820.2"	"949.1"	"1120.1"	"838.3"	"1057.3"	"922.2"	"1720.5"	"3150.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q09028"	"Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3"	"0.000"	""	"29"	"11"	"22"	"5"	"425"	"47.6"	"4.89"	"3443.70"	"38.32"	"9"	"11"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400, Pf12265"	"5928"	"ENSG00000162521"	"RBBP4"	"B2R6G9; B4DRH0; D3DPQ3; hsa:5928; P31149; Q09028; Q53H02; Q96BV9"	"RNA Polymerase I Transcription Initiation; Potential therapeutics for SARS; Oxidative Stress Induced Senescence; Activation of anterior HOX genes in hindbrain development during early embryogenesis; HCMV Early Events; Deposition of new CENPA-containing nucleosomes at the centromere; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6; HDACs deacetylate histones; PKMTs methylate histone lysines; PRC2 methylates histones and DNA; Defective pyroptosis; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; G1/S-Specific Transcription; Regulation of TP53 Activity through Acetylation; Polo-like kinase mediated events; Cyclin E associated events during G1/S transition ; Transcription of E2F targets under negative control by DREAM complex; Cyclin A:Cdk2-associated events at S phase entry; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"	"Retinoblastoma gene in cancer; Interactome of polycomb repressive complex 2 (PRC2) ; Tumor suppressor activity of SMARCB1; Epithelial to mesenchymal transition in colorectal cancer; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; Pleural mesothelioma; DYRK1A involvement regarding cell proliferation in brain development"	"28"	"7"	"1408.9"	"733.2"	"1375.7"	"1261.2"	"1377.5"	"1617.4"	"1358.6"	"1649.5"	"1301.8"	"2212.5"	"3430.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13247"	"Serine/arginine-rich splicing factor 6 OS=Homo sapiens OX=9606 GN=SRSF6 PE=1 SV=2"	"0.000"	""	"28"	"10"	"24"	"6"	"344"	"39.6"	"11.43"	"3450.11"	"38.28"	"8"	"9"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"6431"	"ENSG00000124193"	"SRSF6"	"B7Z6J3; E1P5W6; hsa:6431; Q13244; Q13245; Q13247; Q96J06; Q9UJB8; Q9Y3N7"	"RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing"	"mRNA processing"	"7"	"6"	"4901.3"	"1470.5"	"2858.9"	"2430.0"	"2737.1"	"2872.9"	"2411.2"	"3281.3"	"2707.3"	"4571.9"	"7327.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6I3"	"Epsin-1 OS=Homo sapiens OX=9606 GN=EPN1 PE=1 SV=2"	"0.000"	""	"19"	"9"	"18"	"9"	"576"	"60.3"	"4.83"	"2525.30"	"38.23"	"7"	"9"	"transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf01417, Pf02809"	"29924"	"ENSG00000063245"	"EPN1"	"hsa:29924; Q86ST3; Q9HA18; Q9Y6I3"	"Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation"	"VEGFA-VEGFR2 signaling; EGF/EGFR signaling pathway"	"5"	"0"	"329.1"	"144.7"	"342.9"	"322.1"	"375.9"	"572.2"	"605.1"	"1386.9"	"1256.4"	"2390.1"	"3630.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13797"	"Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3 PE=1 SV=4"	"0.000"	""	"19"	"10"	"21"	"10"	"630"	"70.8"	"5.60"	"4550.56"	"38.16"	"10"	"9"	"cell organization and biogenesis;developmental processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf13499"	"5358"	"ENSG00000102024"	"PLS3"	"A8K579; B1AQ09; B4DGB4; B7Z6M1; hsa:5358; P13797; Q86YI6"	""	""	"0"	"0"	"1123.7"	"463.9"	"1019.4"	"870.1"	"927.9"	"1112.0"	"806.5"	"998.5"	"758.7"	"1354.2"	"2646.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13242"	"Serine/arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1"	"0.000"	""	"38"	"10"	"26"	"9"	"221"	"25.5"	"8.65"	"4327.65"	"38.12"	"10"	"9"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00076"	"8683"	"ENSG00000111786"	"SRSF9"	"hsa:8683; Q13242; Q52LD1"	"mRNA Splicing - Major Pathway; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"mRNA processing"	"6"	"0"	"2317.9"	"779.9"	"1512.7"	"1290.7"	"1407.6"	"1588.3"	"1323.5"	"1619.0"	"1438.5"	"1993.2"	"2057.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07814"	"Bifunctional glutamate/proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5"	"0.000"	""	"7"	"8"	"16"	"8"	"1512"	"170.5"	"7.33"	"2710.43"	"37.79"	"4"	"7"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00043, Pf00458, Pf00587, Pf00749, Pf03129, Pf03950, Pf09180"	"2058"	"ENSG00000136628"	"EPRS1"	"A0AVA9; B9EGH3; hsa:2058; P07814; Q05BP6; Q05DF8; Q5DSM1; Q5H9S5; Q6PD57; Q86X73"	"tRNA modification in the nucleus and cytosol; Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"Parkinson's disease pathway; VEGFA-VEGFR2 signaling; Amino acid metabolism"	"6"	"0"	"609.3"	"240.1"	"506.1"	"432.8"	"468.6"	"536.3"	"402.1"	"550.6"	"455.7"	"1028.2"	"3560.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86YS7"	"C2 domain-containing protein 5 OS=Homo sapiens OX=9606 GN=C2CD5 PE=1 SV=1"	"0.000"	""	"12"	"13"	"21"	"13"	"1000"	"110.4"	"5.69"	"3217.28"	"37.51"	"9"	"10"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00168"	"9847"	"ENSG00000111731"	"C2CD5"	"B4DJ03; B4DRN7; B7ZLL0; F5H2A1; F5H5R1; hsa:9847; O60280; Q17RY7; Q7Z619; Q86SU3; Q86YS7"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"	""	"1"	"0"	"538.3"	"254.8"	"515.8"	"456.6"	"472.2"	"928.7"	"1369.3"	"2888.6"	"3129.7"	"6420.7"	"9235.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86V81"	"THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3"	"0.000"	""	"36"	"6"	"13"	"6"	"257"	"26.9"	"11.15"	"1809.34"	"37.50"	"4"	"5"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf13865"	"10189"	""	"ALYREF"	"hsa:10189; O43672; Q86V81"	"mRNA Splicing - Major Pathway; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript"	""	"7"	"0"	"1682.7"	"502.9"	"1240.3"	"1074.9"	"1227.8"	"1450.9"	"1040.0"	"1335.2"	"899.0"	"1643.4"	"2599.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92917"	"G-patch domain and KOW motifs-containing protein OS=Homo sapiens OX=9606 GN=GPKOW PE=1 SV=2"	"0.000"	""	"21"	"7"	"17"	"7"	"476"	"52.2"	"6.15"	"3115.10"	"37.41"	"4"	"7"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00467, Pf12656"	"27238"	"ENSG00000068394"	"GPKOW"	"hsa:27238; Q59EK5; Q92917; Q9BQA8"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"485.5"	"183.1"	"369.2"	"297.1"	"373.4"	"431.2"	"331.4"	"454.2"	"501.6"	"1556.8"	"3974.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UQ35"	"Serine/arginine repetitive matrix protein 2 OS=Homo sapiens OX=9606 GN=SRRM2 PE=1 SV=2"	"0.000"	""	"5"	"8"	"15"	"8"	"2752"	"299.4"	"12.06"	"1874.16"	"37.35"	"5"	"8"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf08312"	"23524"	"ENSG00000167978"	"SRRM2"	"A6NKB9; D3DU97; hsa:23524; O15038; O94803; Q6NSL3; Q6PIM3; Q6PK40; Q8IW17; Q96GY7; Q9P0G1; Q9UHA8; Q9UQ35; Q9UQ36; Q9UQ37; Q9UQ38; Q9UQ40"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"1344.9"	"380.7"	"855.2"	"783.2"	"899.1"	"1163.5"	"1183.8"	"1788.8"	"1176.9"	"1641.4"	"2838.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92688"	"Acidic leucine-rich nuclear phosphoprotein 32 family member B OS=Homo sapiens OX=9606 GN=ANP32B PE=1 SV=1"	"0.000"	""	"27"	"7"	"21"	"5"	"251"	"28.8"	"4.06"	"3133.83"	"37.19"	"6"	"5"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf12799"	"10541"	"ENSG00000136938"	"ANP32B"	"B2R9C7; hsa:10541; O00655; P78458; P78459; Q92688"	""	""	"0"	"0"	"779.9"	"379.6"	"790.3"	"665.1"	"753.0"	"992.1"	"788.9"	"963.9"	"639.0"	"936.0"	"1443.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49756"	"RNA-binding protein 25 OS=Homo sapiens OX=9606 GN=RBM25 PE=1 SV=3"	"0.000"	""	"15"	"11"	"24"	"11"	"843"	"100.1"	"6.32"	"4609.83"	"37.18"	"10"	"8"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf01480"	"58517"	"ENSG00000119707"	"RBM25"	"A0PJL9; B2RNA8; B3KT03; hsa:58517; P49756; Q2TA72; Q5XJ17; Q6P665; Q9H6A1; Q9UEQ5; Q9UIE9"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"2101.1"	"532.4"	"1211.1"	"1032.2"	"1232.8"	"1310.8"	"993.7"	"1451.9"	"1098.2"	"2668.5"	"4930.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P58876"	"Histone H2B type 1-D OS=Homo sapiens OX=9606 GN=H2BC5 PE=1 SV=2"	"0.000"	""	"49"	"6"	"21"	"2"	"126"	"13.9"	"10.32"	"3904.94"	"37.17"	"6"	"5"	""	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125"	"3017"	"ENSG00000158373"	"H2BC5"	"hsa:3017; P58876"	"Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Estrogen-dependent gene expression; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; Meiotic recombination; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; DNA Damage/Telomere Stress Induced Senescence; Nonhomologous End-Joining (NHEJ); E3 ubiquitin ligases ubiquitinate target proteins; Amyloid fiber formation; Meiotic synapsis; HCMV Late Events; HCMV Early Events; Transcriptional regulation by small RNAs; Deposition of new CENPA-containing nucleosomes at the centromere; B-WICH complex positively regulates rRNA expression; Formation of the beta-catenin:TCF transactivating complex; Oxidative Stress Induced Senescence; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Pre-NOTCH Transcription and Translation; Senescence-Associated Secretory Phenotype (SASP); RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; HATs acetylate histones; RNA Polymerase I Promoter Escape; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Packaging Of Telomere Ends; Condensation of Prophase Chromosomes; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	""	"43"	"0"	"913.4"	"369.2"	"858.2"	"612.2"	"712.6"	"869.5"	"709.8"	"824.8"	"624.3"	"918.7"	"907.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75821"	"Eukaryotic translation initiation factor 3 subunit G OS=Homo sapiens OX=9606 GN=EIF3G PE=1 SV=2"	"0.000"	""	"20"	"7"	"17"	"7"	"320"	"35.6"	"6.13"	"2397.13"	"37.03"	"6"	"7"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf12353"	"8666"	"ENSG00000130811"	"EIF3G"	"hsa:8666; O14801; O75821; Q969U5"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"8"	"0"	"1766.6"	"698.2"	"1558.2"	"1374.4"	"1497.0"	"1697.6"	"1118.3"	"1484.1"	"964.4"	"1832.4"	"3416.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86UE4"	"Protein LYRIC OS=Homo sapiens OX=9606 GN=MTDH PE=1 SV=2"	"0.000"	""	"16"	"7"	"12"	"7"	"582"	"63.8"	"9.32"	"1547.84"	"37.01"	"3"	"6"	"signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf15686"	"92140"	"ENSG00000147649"	"MTDH"	"hsa:92140; Q05DH2; Q52QU9; Q6PK07; Q86UE4; Q8TCX3"	""	"Gastric cancer network 2; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; CCL18 signaling pathway"	"3"	"0"	"473.5"	"194.1"	"411.9"	"375.8"	"417.7"	"468.1"	"330.4"	"536.5"	"480.4"	"2505.4"	"7255.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13347"	"Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1"	"0.000"	""	"30"	"9"	"23"	"8"	"325"	"36.5"	"5.64"	"3680.85"	"36.95"	"9"	"9"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf00400"	"8668"	"ENSG00000084623"	"EIF3I"	"hsa:8668; Q13347"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"8"	"1"	"1618.8"	"716.1"	"1392.3"	"1301.9"	"1380.1"	"1584.8"	"1261.3"	"1529.0"	"1071.7"	"1926.6"	"3049.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23527"	"Histone H2B type 1-O OS=Homo sapiens OX=9606 GN=H2BC17 PE=1 SV=3"	"0.000"	""	"49"	"6"	"21"	"2"	"126"	"13.9"	"10.32"	"3994.36"	"36.95"	"6"	"5"	"cell organization and biogenesis"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125"	"8348"	"ENSG00000274641"	"H2BC17"	"hsa:8348; P23527; Q3KPI7; Q8TCV6"	"HCMV Late Events; HCMV Early Events; Transcriptional regulation by small RNAs; E3 ubiquitin ligases ubiquitinate target proteins; Amyloid fiber formation; Meiotic synapsis; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Deposition of new CENPA-containing nucleosomes at the centromere; B-WICH complex positively regulates rRNA expression; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Formation of the beta-catenin:TCF transactivating complex; Oxidative Stress Induced Senescence; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Pre-NOTCH Transcription and Translation; Senescence-Associated Secretory Phenotype (SASP); RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; HATs acetylate histones; RNA Polymerase I Promoter Escape; Meiotic recombination; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Packaging Of Telomere Ends; Condensation of Prophase Chromosomes; DNA Damage/Telomere Stress Induced Senescence; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; Nonhomologous End-Joining (NHEJ); RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	""	"43"	"6"	"1601.3"	"751.2"	"1223.7"	"975.6"	"1075.3"	"1355.9"	"1218.9"	"1256.2"	"1079.3"	"1504.2"	"1805.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P68431"	"Histone H3.1 OS=Homo sapiens OX=9606 GN=H3C1 PE=1 SV=2"	"0.000"	""	"32"	"8"	"23"	"8"	"136"	"15.4"	"11.12"	"3802.34"	"36.89"	"8"	"6"	"cell organization and biogenesis;other metabolic processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125"	"8350; 8351; 8352; 8353; 8354; 8355; 8356; 8357; 8358; 8968"	"ENSG00000197153; ENSG00000197409; ENSG00000273983; ENSG00000274750; ENSG00000275379; ENSG00000275714; ENSG00000277775; ENSG00000278828; ENSG00000286522; ENSG00000287080"	"H3C1; H3C10; H3C11; H3C12; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8"	"A0PJT7; A5PLR1; hsa:8350; hsa:8351; hsa:8352; hsa:8353; hsa:8354; hsa:8355; hsa:8356; hsa:8357; hsa:8358; hsa:8968; P02295; P02296; P16106; P68431; Q6ISV8; Q6NWP8; Q6NWP9; Q6NXU4; Q71DJ3; Q93081"	"Transcriptional regulation by small RNAs; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; HATs acetylate histones; Oxidative Stress Induced Senescence; Pre-NOTCH Transcription and Translation; Factors involved in megakaryocyte development and platelet production; Condensation of Prophase Chromosomes; HCMV Late Events; HCMV Early Events; Amyloid fiber formation; RUNX1 regulates transcription of genes involved in differentiation of HSCs; B-WICH complex positively regulates rRNA expression; Formation of the beta-catenin:TCF transactivating complex; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; Interleukin-7 signaling; Senescence-Associated Secretory Phenotype (SASP); RMTs methylate histone arginines; HDMs demethylate histones; PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; RNA Polymerase I Promoter Escape; Meiotic recombination; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	"Histone modifications; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma"	"36"	"0"	"3221.2"	"1175.2"	"2270.9"	"1827.0"	"1934.2"	"2234.8"	"1987.2"	"2250.2"	"1994.0"	"3163.1"	"2802.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P36578"	"60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5"	"0.000"	""	"25"	"11"	"26"	"11"	"427"	"47.7"	"11.06"	"4687.06"	"36.86"	"11"	"9"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00573, Pf14374"	"6124"	"ENSG00000174444"	"RPL4"	"A8K502; hsa:6124; P36578; P39029; Q4VBR0; Q969Z9"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"2605.8"	"1110.0"	"2122.6"	"1894.7"	"1959.7"	"2364.3"	"1827.7"	"2328.7"	"1771.5"	"2975.7"	"4194.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IX12"	"Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2"	"0.000"	""	"8"	"10"	"24"	"10"	"1150"	"132.7"	"5.76"	"4308.62"	"36.76"	"10"	"10"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02037, Pf14443, Pf14444, Pf19256, Pf19257"	"55749"	"ENSG00000060339"	"CCAR1"	"A0JLT7; A1L4P7; A8K9D4; B4DNP8; B4DRK8; hsa:55749; Q32NE3; Q5EBM3; Q5VUP6; Q6PIZ0; Q6X935; Q8IX12; Q9H8N4; Q9NVA7; Q9NVQ0; Q9NWM6"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"2088.9"	"635.3"	"1553.1"	"1268.1"	"1566.0"	"1776.5"	"1142.7"	"1640.9"	"1202.0"	"2246.0"	"3719.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99584"	"Protein S100-A13 OS=Homo sapiens OX=9606 GN=S100A13 PE=1 SV=1"	"0.000"	""	"40"	"4"	"15"	"4"	"98"	"11.5"	"6.16"	"1904.61"	"36.72"	"4"	"4"	"transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01023"	"6284"	"ENSG00000189171"	"S100A13"	"hsa:6284; Q52PI9; Q6FGF8; Q99584"	""	""	"0"	"0"	"295.9"	"142.6"	"252.2"	"213.0"	"275.1"	"289.9"	"228.6"	"334.4"	"609.7"	"3884.6"	"9567.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75475"	"PC4 and SFRS1-interacting protein OS=Homo sapiens OX=9606 GN=PSIP1 PE=1 SV=1"	"0.000"	""	"17"	"8"	"22"	"8"	"530"	"60.1"	"9.13"	"3295.85"	"36.68"	"6"	"8"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00855, Pf11467"	"11168"	"ENSG00000164985"	"PSIP1"	"D3DRI9; hsa:11168; O00256; O75475; O95368; Q6P391; Q86YB9; Q9NZI3; Q9UER6"	"Vpr-mediated nuclear import of PICs; Formation of WDR5-containing histone-modifying complexes; 2-LTR circle formation; Integration of viral DNA into host genomic DNA; Autointegration results in viral DNA circles; APOBEC3G mediated resistance to HIV-1 infection"	"MECP2 and associated Rett syndrome"	"8"	"0"	"771.6"	"340.6"	"640.1"	"591.2"	"647.0"	"777.5"	"581.0"	"916.8"	"646.1"	"1776.6"	"5031.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6NSI4"	"RPA-related protein RADX OS=Homo sapiens OX=9606 GN=RADX PE=1 SV=2"	"0.000"	""	"15"	"10"	"20"	"10"	"855"	"97.5"	"8.41"	"3927.00"	"36.67"	"9"	"9"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf17659"	"55086"	"ENSG00000147231"	"RADX"	"H7BY89; hsa:55086; Q4G0L7; Q5JQS1; Q5JRF9; Q6NSI4; Q6PHY5; Q6PII9; Q6PJU8; Q9H7W5; Q9NWA6"	""	""	"0"	"0"	"838.6"	"370.7"	"765.5"	"683.4"	"779.9"	"917.3"	"639.9"	"835.0"	"647.4"	"1160.1"	"2249.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96G61"	"Diphosphoinositol polyphosphate phosphohydrolase 3-beta OS=Homo sapiens OX=9606 GN=NUDT11 PE=1 SV=1"	"0.000"	""	"60"	"9"	"17"	"1"	"164"	"18.5"	"5.99"	"2808.22"	"36.64"	"5"	"9"	"other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00293"	"55190"	"ENSG00000196368"	"NUDT11"	"hsa:55190; Q96G61; Q9NVN0"	"Synthesis of pyrophosphates in the cytosol"	""	"1"	"0"	"62.2"	"36.4"	"72.4"	"81.3"	"71.4"	"171.1"	"244.1"	"624.4"	"526.0"	"1301.0"	"1911.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14554"	"Protein disulfide-isomerase A5 OS=Homo sapiens OX=9606 GN=PDIA5 PE=1 SV=1"	"0.000"	""	"21"	"9"	"19"	"9"	"519"	"59.6"	"7.91"	"3266.06"	"36.60"	"8"	"9"	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00085"	"10954"	"ENSG00000065485"	"PDIA5"	"D3DN95; hsa:10954; Q14554; Q9BV43"	"XBP1(S) activates chaperone genes"	""	"1"	"0"	"443.3"	"170.8"	"369.3"	"323.9"	"384.4"	"399.5"	"312.7"	"649.4"	"1197.7"	"5768.0"	"4494.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3I0"	"RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1"	"0.000"	""	"23"	"11"	"21"	"11"	"505"	"55.2"	"7.23"	"3238.00"	"36.47"	"10"	"11"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01139"	"51493"	"ENSG00000100220"	"RTCB"	"B2R6A8; hsa:51493; Q6IAI0; Q9BWL4; Q9NTH1; Q9P037; Q9P0J3; Q9Y3I0"	"tRNA processing in the nucleus"	"Unfolded protein response"	"2"	"0"	"1347.2"	"564.2"	"1124.0"	"957.8"	"1154.5"	"1301.1"	"1041.3"	"1276.8"	"1022.7"	"2076.9"	"4265.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15293"	"Reticulocalbin-1 OS=Homo sapiens OX=9606 GN=RCN1 PE=1 SV=1"	"0.000"	""	"22"	"7"	"17"	"7"	"331"	"38.9"	"5.00"	"3563.59"	"36.12"	"5"	"6"	"developmental processes"	"ER/Golgi"	"other molecular function"	"Pf13202"	"5954"	"ENSG00000049449"	"RCN1"	"B7Z1M1; D3DR00; hsa:5954; Q15293"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation"	"VEGFA-VEGFR2 signaling"	"3"	"0"	"1468.1"	"715.3"	"1728.3"	"1366.3"	"1588.4"	"1731.4"	"1234.2"	"1547.3"	"1104.8"	"2125.4"	"2584.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P57740"	"Nuclear pore complex protein Nup107 OS=Homo sapiens OX=9606 GN=NUP107 PE=1 SV=1"	"0.000"	""	"12"	"10"	"19"	"10"	"925"	"106.3"	"5.43"	"3008.47"	"35.87"	"9"	"9"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes"	"other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf04121"	"57122"	"ENSG00000111581"	"NUP107"	"B4DZ67; hsa:57122; P57740; Q6PJE1"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; SUMOylation of DNA damage response and repair proteins; Vpr-mediated nuclear import of PICs; SARS-CoV-2 activates/modulates innate and adaptive immune responses; RHO GTPases Activate Formins; Regulation of HSF1-mediated heat shock response; SUMOylation of chromatin organization proteins; HCMV Late Events; HCMV Early Events; EML4 and NUDC in mitotic spindle formation; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; snRNP Assembly; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Postmitotic nuclear pore complex (NPC) reformation"	"Gastric cancer network 1; Primary ovarian insufficiency"	"37"	"0"	"748.2"	"356.8"	"723.9"	"685.4"	"714.4"	"866.4"	"600.2"	"764.2"	"611.8"	"1188.8"	"1976.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19388"	"DNA-directed RNA polymerases I, II, and III subunit RPABC1 OS=Homo sapiens OX=9606 GN=POLR2E PE=1 SV=4"	"0.000"	""	"45"	"7"	"15"	"7"	"210"	"24.5"	"5.95"	"2294.54"	"35.86"	"5"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01191, Pf03871"	"5434"	"ENSG00000099817"	"POLR2E"	"B2R6L4; D6W5Y1; hsa:5434; O43380; P19388; Q6PIH5; Q9BT06"	"mRNA Splicing - Major Pathway; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; B-WICH complex positively regulates rRNA expression; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"57"	"0"	"616.5"	"260.5"	"467.7"	"394.1"	"493.9"	"528.5"	"416.9"	"644.3"	"1246.9"	"3237.6"	"4906.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52948"	"Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4"	"0.000"	""	"8"	"12"	"22"	"12"	"1817"	"197.5"	"6.40"	"3546.02"	"35.81"	"11"	"11"	"cell organization and biogenesis;protein metabolism;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04096, Pf12110"	"4928"	"ENSG00000110713"	"NUP98"	"hsa:4928; P52948; Q8IUT2; Q8WYB0; Q96E54; Q9H3Q4; Q9NT02; Q9UF57; Q9UHX0; Q9Y6J4; Q9Y6J5"	""	"SARS-CoV-2 innate immunity evasion and cell-specific immune response"	"1"	"0"	"737.1"	"324.9"	"765.9"	"671.1"	"705.9"	"840.1"	"558.2"	"708.8"	"557.8"	"1051.9"	"1725.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96A65"	"Exocyst complex component 4 OS=Homo sapiens OX=9606 GN=EXOC4 PE=1 SV=1"	"0.000"	""	"9"	"7"	"16"	"7"	"974"	"110.4"	"6.49"	"2315.28"	"35.64"	"4"	"7"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf04048"	"60412"	"ENSG00000131558"	"EXOC4"	"E9PED2; hsa:60412; Q541U8; Q96A65; Q9C0G4; Q9H9K0; Q9P102"	"Insulin processing; Translocation of SLC2A4 (GLUT4) to the plasma membrane; VxPx cargo-targeting to cilium"	"Ciliary landscape"	"4"	"0"	"207.2"	"104.7"	"168.8"	"137.5"	"190.1"	"182.2"	"184.0"	"398.7"	"759.1"	"2309.7"	"3611.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13243"	"Serine/arginine-rich splicing factor 5 OS=Homo sapiens OX=9606 GN=SRSF5 PE=1 SV=1"	"0.000"	""	"25"	"7"	"14"	"6"	"272"	"31.2"	"11.59"	"1422.00"	"35.50"	"5"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00076"	"6430"	"ENSG00000100650"	"SRSF5"	"hsa:6430; O14797; Q13243; Q16662; Q49AD6; Q6FGE0"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"mRNA processing"	"6"	"0"	"1591.9"	"579.8"	"1219.0"	"1053.8"	"1201.4"	"1272.8"	"979.3"	"1323.2"	"913.5"	"1558.3"	"1856.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3F4"	"Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1"	"0.000"	""	"28"	"8"	"20"	"8"	"350"	"38.4"	"5.12"	"3933.99"	"35.40"	"8"	"8"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00400"	"11171"	"ENSG00000023734"	"STRAP"	"B2R5S5; B4DNJ6; hsa:11171; Q5TZT4; Q9NTK0; Q9UQC8; Q9Y3F4"	"Downregulation of TGF-beta receptor signaling"	"Epithelial to mesenchymal transition in colorectal cancer"	"2"	"0"	"880.1"	"377.6"	"785.6"	"752.2"	"818.0"	"948.7"	"720.7"	"920.4"	"698.2"	"1165.3"	"1943.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P12081"	"Histidine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=HARS1 PE=1 SV=2"	"0.000"	""	"22"	"11"	"17"	"11"	"509"	"57.4"	"5.88"	"2099.82"	"35.32"	"6"	"9"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00458, Pf03129, Pf13393"	"3035"	"ENSG00000170445"	"HARS1"	"B4DHQ1; B4DY73; D6REN6; hsa:3035; J3KNE5; P12081"	"Cytosolic tRNA aminoacylation"	"Allograft rejection"	"2"	"0"	"469.8"	"210.3"	"375.7"	"343.3"	"386.2"	"418.6"	"346.4"	"488.0"	"798.7"	"3912.9"	"9888.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P40227"	"T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3"	"0.000"	""	"19"	"9"	"21"	"9"	"531"	"58.0"	"6.68"	"3430.28"	"35.29"	"7"	"8"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00118"	"908"	"ENSG00000146731"	"CCT6A"	"A6NCD2; hsa:908; P40227; Q3KP28; Q75LP4; Q96S46"	"Formation of tubulin folding intermediates by CCT/TriC; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; RHOBTB2 GTPase cycle; Folding of actin by CCT/TriC"	"16p11.2 proximal deletion syndrome"	"7"	"0"	"1644.5"	"702.3"	"1248.1"	"1059.1"	"1323.8"	"1412.5"	"1125.1"	"1424.5"	"1246.0"	"2363.1"	"4807.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15428"	"Splicing factor 3A subunit 2 OS=Homo sapiens OX=9606 GN=SF3A2 PE=1 SV=2"	"0.000"	""	"15"	"8"	"19"	"8"	"464"	"49.2"	"9.64"	"4415.27"	"35.28"	"8"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf12874, Pf16835"	"8175"	"ENSG00000104897"	"SF3A2"	"B2RBU1; D6W605; hsa:8175; O75245; Q15428"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"0"	"1859.5"	"677.6"	"1454.4"	"1195.2"	"1324.5"	"1619.3"	"1110.4"	"1651.3"	"1143.9"	"2012.4"	"3481.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92945"	"Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4"	"0.000"	""	"19"	"9"	"16"	"7"	"711"	"73.1"	"7.30"	"2553.99"	"35.12"	"7"	"9"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf09005"	"8570"	"ENSG00000088247"	"KHSRP"	"hsa:8570; O00301; Q59EZ9; Q5U4P6; Q92945; Q9UNT5; Q9UQH5"	"ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA"	"Pre-implantation embryo"	"3"	"0"	"877.2"	"252.2"	"498.3"	"390.1"	"521.3"	"514.0"	"457.9"	"545.0"	"524.1"	"853.2"	"1561.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P78406"	"mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1"	"0.000"	""	"30"	"9"	"16"	"9"	"368"	"40.9"	"7.83"	"3426.98"	"34.51"	"8"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00400"	"8480"	"ENSG00000101146"	"RAE1"	"A8K882; hsa:8480; O15306; P78406; Q3SYL7; Q5TCH8; Q6V708; Q9H100; Q9NQM6"	"Transcriptional regulation by small RNAs; ISG15 antiviral mechanism; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Regulation of HSF1-mediated heat shock response; HCMV Early Events; HCMV Late Events; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus"	"IL-18 signaling pathway; SARS-CoV-2 innate immunity evasion and cell-specific immune response"	"30"	"0"	"1273.3"	"504.7"	"1220.0"	"1253.3"	"1237.0"	"1493.0"	"1020.2"	"1401.1"	"922.1"	"2246.8"	"4940.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P40939"	"Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2"	"0.000"	""	"13"	"9"	"23"	"9"	"763"	"82.9"	"9.04"	"3822.15"	"34.45"	"7"	"9"	"other metabolic processes;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf00378, Pf00725, Pf02737"	"3030"	"ENSG00000084754"	"HADHA"	"B2R7L4; B4DYP2; hsa:3030; P40939; Q16679; Q53T69; Q53TA2; Q96GT7; Q9UQC5"	"Acyl chain remodeling of CL; mitochondrial fatty acid beta-oxidation of unsaturated fatty acids; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of myristoyl-CoA to lauroyl-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA; Beta oxidation of palmitoyl-CoA to myristoyl-CoA"	"Fatty acid beta-oxidation; Mitochondrial long chain fatty acid beta-oxidation; Valproic acid pathway; Mitochondrial fatty acid oxidation disorders; Sudden infant death syndrome (SIDS) susceptibility pathways"	"13"	"0"	"1784.6"	"636.4"	"1336.1"	"1039.0"	"1249.8"	"1438.8"	"1181.8"	"1504.8"	"1273.6"	"2420.1"	"4896.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07355"	"Annexin A2 OS=Homo sapiens OX=9606 GN=ANXA2 PE=1 SV=2"	"0.000"	""	"35"	"11"	"21"	"11"	"339"	"38.6"	"7.75"	"3500.00"	"34.37"	"10"	"11"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"non-structural extracellular;extracellular matrix;plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"transporter activity;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00191"	"302"	"ENSG00000182718"	"ANXA2"	"hsa:302; P07355; Q567R4; Q6N0B3; Q8TBV2; Q96DD5; Q9UDH8"	"Neutrophil degranulation; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Smooth Muscle Contraction; Dissolution of Fibrin Clot"	"Gastrin signaling pathway; CCL18 signaling pathway; Prostaglandin synthesis and regulation"	"7"	"0"	"1515.8"	"590.2"	"986.2"	"762.1"	"1044.2"	"1094.8"	"947.1"	"1174.2"	"1275.3"	"2030.2"	"2299.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H307"	"Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5"	"0.000"	""	"17"	"10"	"21"	"10"	"717"	"81.6"	"7.14"	"4232.80"	"34.32"	"9"	"8"	"cell adhesion;RNA metabolism OR transcription;other metabolic processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04696, Pf04697"	"5411"	"ENSG00000100941"	"PNN"	"B4DZX8; hsa:5411; O60899; Q53EM7; Q6P5X4; Q7KYL1; Q99738; Q9H307; Q9UHZ9; Q9UQR9"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"1444.4"	"303.2"	"697.1"	"516.3"	"758.0"	"737.8"	"648.6"	"821.1"	"679.0"	"1127.6"	"2244.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13428"	"Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3"	"0.000"	""	"8"	"11"	"23"	"11"	"1488"	"152.0"	"9.04"	"4752.13"	"34.24"	"11"	"10"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf03546"	"6949"	"ENSG00000070814"	"TCOF1"	"A0JLU0; B4E111; hsa:6949; Q13428; Q6SC72; Q7Z5W9; Q96A52; Q99408; Q99860"	""	""	"0"	"0"	"1192.6"	"501.6"	"1113.1"	"1022.7"	"1077.7"	"1415.3"	"1177.8"	"1843.5"	"1244.8"	"2364.3"	"4472.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60716"	"Catenin delta-1 OS=Homo sapiens OX=9606 GN=CTNND1 PE=1 SV=1"	"0.000"	""	"12"	"8"	"16"	"8"	"968"	"108.1"	"6.23"	"3798.45"	"34.10"	"7"	"7"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00514"	"1500"	"ENSG00000198561"	"CTNND1"	"A8K939; hsa:1500; O15088; O60713; O60714; O60715; O60716; O60935; Q6DHZ7; Q6RBX8; Q9UP71; Q9UP72; Q9UP73"	"VEGFR2 mediated vascular permeability; Adherens junctions interactions; InlA-mediated entry of Listeria monocytogenes into host cells; Regulation of CDH11 function; Regulation of CDH19 Expression and Function; CDH11 homotypic and heterotypic interactions"	"VEGFA-VEGFR2 signaling; Wnt signaling pathway and pluripotency"	"8"	"0"	"939.2"	"426.0"	"890.2"	"713.8"	"785.9"	"927.4"	"732.3"	"975.5"	"800.9"	"1254.0"	"2527.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30419"	"Glycylpeptide N-tetradecanoyltransferase 1 OS=Homo sapiens OX=9606 GN=NMT1 PE=1 SV=2"	"0.000"	""	"18"	"7"	"14"	"7"	"496"	"56.8"	"7.80"	"2461.63"	"34.06"	"6"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf01233, Pf02799"	"4836"	"ENSG00000136448"	"NMT1"	"A8K7C1; hsa:4836; P30419; Q9UE09"	"Inactivation, recovery and regulation of the phototransduction cascade; Late Phase of HIV Life Cycle; Activation, myristolyation of BID and translocation to mitochondria"	""	"3"	"0"	"348.1"	"174.1"	"290.5"	"301.9"	"337.1"	"358.9"	"296.5"	"459.9"	"481.7"	"1921.5"	"4540.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q05397"	"Focal adhesion kinase 1 OS=Homo sapiens OX=9606 GN=PTK2 PE=1 SV=2"	"0.000"	""	"8"	"8"	"17"	"8"	"1052"	"119.2"	"6.62"	"2530.55"	"34.04"	"6"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;kinase activity;other molecular function"	"Pf00373, Pf03623, Pf07714, Pf18038"	"5747"	"ENSG00000169398"	"PTK2"	"B4E2N6; F5H4S4; hsa:5747; J3QT16; Q05397; Q14291; Q8IYN9; Q9UD85"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; EPHB-mediated forward signaling; Signal regulatory protein family interactions; DCC mediated attractive signaling; RAF/MAP kinase cascade; VEGFA-VEGFR2 Pathway; Estrogen-dependent nuclear events downstream of ESR-membrane signaling; NCAM signaling for neurite out-growth; MET activates PTK2 signaling; GRB2:SOS provides linkage to MAPK signaling for Integrins ; p130Cas linkage to MAPK signaling for integrins; Apoptotic cleavage of cellular proteins"	"Androgen receptor signaling pathway; Integrin-mediated cell adhesion; RANKL/RANK signaling pathway; Leptin signaling pathway; Prolactin signaling pathway; Corticotropin-releasing hormone signaling pathway; Alpha 6 beta 4 signaling pathway; Primary focal segmental glomerulosclerosis (FSGS); Apoptosis-related network due to altered Notch3 in ovarian cancer; Focal adhesion; Hepatocyte growth factor receptor signaling; Overview of nanoparticle effects; MFAP5-mediated ovarian cancer cell motility and invasiveness; RAC1/PAK1/p38/MMP2 pathway; Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Prion disease pathway; PI3K-Akt signaling pathway; EGF/EGFR signaling pathway; Hippo-Merlin signaling dysregulation; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Small cell lung cancer; Gastrin signaling pathway; Netrin-UNC5B signaling pathway; Pleural mesothelioma; Regulation of actin cytoskeleton; 2q13 copy number variation syndrome; TROP2 regulatory signaling; A network map of Macrophage-stimulating protein (MSP) signaling; ErbB signaling pathway"	"48"	"0"	"432.3"	"205.8"	"407.4"	"361.0"	"452.6"	"527.5"	"547.5"	"1416.3"	"2129.2"	"5476.3"	"5941.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A0FGR8"	"Extended synaptotagmin-2 OS=Homo sapiens OX=9606 GN=ESYT2 PE=1 SV=1"	"0.000"	""	"10"	"7"	"16"	"7"	"921"	"102.3"	"9.26"	"2871.83"	"33.97"	"5"	"7"	"cell organization and biogenesis;transport"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00168, Pf17047"	"57488"	"ENSG00000117868"	"ESYT2"	"A0FGR8; A4D229; hsa:57488; Q69YJ2; Q6UKI4; Q6ZTU0; Q6ZVU1; Q9BQS0; Q9NW47; Q9ULJ2"	"Glycosphingolipid metabolism"	""	"1"	"0"	"196.7"	"101.2"	"175.4"	"218.4"	"202.9"	"439.2"	"646.5"	"963.3"	"876.0"	"1554.8"	"1852.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P32119"	"Peroxiredoxin-2 OS=Homo sapiens OX=9606 GN=PRDX2 PE=1 SV=5"	"0.000"	""	"29"	"7"	"18"	"6"	"198"	"21.9"	"5.97"	"4120.08"	"33.92"	"7"	"6"	"cell cycle OR cell proliferation;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00578, Pf10417"	"7001"	"ENSG00000167815"	"PRDX2"	"A8K0C0; hsa:7001; P31945; P32118; P32119; P35701; Q6FHG4; Q92763; Q9UC23"	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models; Detoxification of Reactive Oxygen Species; TP53 Regulates Metabolic Genes"	"Selenium micronutrient network; VEGFA-VEGFR2 signaling"	"5"	"0"	"838.9"	"318.9"	"604.2"	"465.8"	"615.9"	"684.7"	"583.5"	"698.2"	"646.6"	"1057.1"	"2301.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13642"	"Four and a half LIM domains protein 1 OS=Homo sapiens OX=9606 GN=FHL1 PE=1 SV=4"	"0.000"	""	"33"	"8"	"15"	"8"	"323"	"36.2"	"8.97"	"2152.75"	"33.89"	"4"	"7"	"other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00412"	"2273"	"ENSG00000022267"	"FHL1"	"B7Z5T4; B7Z793; hsa:2273; O95212; Q13230; Q13642; Q13645; Q5JXI7; Q5M7Y6; Q6IB30; Q9NZ40; Q9UKZ8; Q9Y630"	""	"Notch signaling pathway"	"1"	"0"	"1008.3"	"512.7"	"1034.9"	"1021.2"	"1029.2"	"1266.1"	"891.0"	"1289.4"	"924.9"	"1611.7"	"2185.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15046"	"Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3"	"0.000"	""	"16"	"10"	"17"	"10"	"597"	"68.0"	"6.35"	"2630.19"	"33.80"	"7"	"10"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00152, Pf01336"	"3735"	"ENSG00000065427"	"KARS1"	"A8MSK1; D3DUK4; hsa:3735; O14946; Q15046; Q96J25; Q9HB23"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation; Mitochondrial tRNA aminoacylation"	""	"3"	"0"	"648.6"	"303.6"	"654.1"	"603.5"	"582.6"	"816.0"	"524.5"	"667.2"	"580.3"	"1835.8"	"6419.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96ST2"	"Protein IWS1 homolog OS=Homo sapiens OX=9606 GN=IWS1 PE=1 SV=2"	"0.000"	""	"12"	"9"	"19"	"9"	"819"	"91.9"	"4.69"	"3460.93"	"33.57"	"8"	"8"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus"	""	"Pf08711"	"55677"	"ENSG00000163166"	"IWS1"	"hsa:55677; Q2TB65; Q6P157; Q8N3E8; Q96MI7; Q96ST2; Q9NV97; Q9NWH8"	"Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events"	""	"3"	"0"	"1291.3"	"564.2"	"1134.3"	"981.3"	"1115.3"	"1451.0"	"1289.4"	"1812.5"	"1303.5"	"2088.7"	"2945.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14927"	"Cytochrome b-c1 complex subunit 7 OS=Homo sapiens OX=9606 GN=UQCRB PE=1 SV=2"	"0.000"	""	"47"	"6"	"16"	"6"	"111"	"13.5"	"8.78"	"4033.13"	"33.54"	"6"	"6"	"other metabolic processes;transport"	"other membranes;mitochondrion"	""	"Pf02271"	"7381"	"ENSG00000156467"	"UQCRB"	"E5RJU0; hsa:7381; P14927; Q6FGD1"	"Respiratory electron transport"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex III assembly"	"4"	"0"	"896.7"	"535.0"	"926.2"	"906.2"	"1004.7"	"1129.0"	"933.4"	"1044.2"	"771.0"	"1220.6"	"1821.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P39019"	"40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2"	"0.000"	""	"41"	"7"	"21"	"7"	"145"	"16.1"	"10.32"	"3949.65"	"33.14"	"7"	"7"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01090"	"6223"	"ENSG00000105372"	"RPS19"	"hsa:6223; P39019"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Complement system; Cytoplasmic ribosomal proteins"	"20"	"0"	"1844.6"	"916.4"	"1644.1"	"1456.9"	"1503.9"	"1922.8"	"1463.4"	"1871.1"	"1405.5"	"2166.1"	"2626.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30153"	"Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4"	"0.000"	""	"15"	"9"	"20"	"9"	"589"	"65.3"	"5.11"	"3930.70"	"33.08"	"8"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02985"	"5518"	"ENSG00000105568"	"PPP2R1A"	"hsa:5518; P30153; Q13773; Q6ICQ3; Q96DH3"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Cyclin A/B1/B2 associated events during G2/M transition; Recruitment of mitotic centrosome proteins and complexes; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Regulation of TP53 Degradation; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Cyclin D associated events in G1; Disassembly of the destruction complex and recruitment of AXIN to the membrane; RAF activation; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; APC truncation mutants have impaired AXIN binding; AXIN missense mutants destabilize the destruction complex; Truncations of AMER1 destabilize the destruction complex; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Spry regulation of FGF signaling; MASTL Facilitates Mitotic Progression; Regulation of glycolysis by fructose 2,6-bisphosphate metabolism; Initiation of Nuclear Envelope (NE) Reformation; Negative regulation of MAPK pathway; Platelet sensitization by LDL; CTLA4 inhibitory signaling; Inhibition of replication initiation of damaged DNA by RB1/E2F1; DARPP-32 events; PP2A-mediated dephosphorylation of key metabolic factors; ERKs are inactivated"	"Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Wnt signaling pathway and pluripotency; PI3K-Akt signaling pathway; 16p11.2 proximal deletion syndrome; Glycogen synthesis and degradation; Cohesin complex - Cornelia de Lange syndrome"	"49"	"0"	"1209.0"	"552.3"	"1148.6"	"1080.0"	"1146.0"	"1406.6"	"926.3"	"1196.7"	"856.3"	"1729.5"	"3424.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08559"	"Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Homo sapiens OX=9606 GN=PDHA1 PE=1 SV=3"	"0.000"	""	"22"	"8"	"22"	"8"	"390"	"43.3"	"8.06"	"4406.56"	"33.08"	"8"	"8"	"other metabolic processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00676"	"5160"	"ENSG00000131828"	"PDHA1"	"A5YVE9; B2R5P7; B7Z3T7; B7Z3X5; hsa:5160; P08559; Q53H41; Q5JPT8; Q9NP12; Q9UBJ8; Q9UBU0; Q9UNG4; Q9UNG5"	"Glyoxylate metabolism and glycine degradation; Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Lipid metabolism pathway; PI3K/AKT/mTOR - vitamin D3 signaling; Metabolic reprogramming in colon cancer; Thiamine metabolic pathways; TCA cycle in senescence; Neuroinflammation and glutamatergic signaling; Acetylcholine synthesis; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"15"	"0"	"1148.0"	"612.8"	"1247.1"	"1089.2"	"1121.7"	"1290.4"	"926.9"	"1165.2"	"977.8"	"1647.4"	"2550.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52292"	"Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1"	"0.000"	""	"19"	"7"	"14"	"7"	"529"	"57.8"	"5.40"	"2605.92"	"33.04"	"6"	"5"	"DNA metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf01749, Pf16186"	"3838"	"ENSG00000182481"	"KPNA2"	"B9EJD6; hsa:3838; P52292; Q53YE3; Q6NVW7; Q9BRU5"	"ISG15 antiviral mechanism; NS1 Mediated Effects on Host Pathways; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Estrogen-dependent gene expression; SARS-CoV-1 activates/modulates innate immune responses; Sensing of DNA Double Strand Breaks; CaMK IV-mediated phosphorylation of CREB; CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde"	""	"8"	"0"	"926.8"	"469.1"	"893.2"	"785.6"	"826.0"	"1008.7"	"772.2"	"1019.8"	"815.9"	"1909.7"	"3016.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15185"	"Prostaglandin E synthase 3 OS=Homo sapiens OX=9606 GN=PTGES3 PE=1 SV=1"	"0.000"	""	"33"	"5"	"14"	"5"	"160"	"18.7"	"4.54"	"3075.95"	"32.92"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf04969"	"10728"	"ENSG00000110958"	"PTGES3"	"A8K7D0; B4DHP2; B4DP11; B4DP21; hsa:10728; Q15185; Q8WU70"	"Estrogen-dependent gene expression; Potential therapeutics for SARS; HSF1 activation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Aryl hydrocarbon receptor signalling; Synthesis of Prostaglandins (PG) and Thromboxanes (TX); Attenuation phase"	"Aryl hydrocarbon receptor pathway; Glucocorticoid receptor pathway; Nuclear receptors meta-pathway"	"11"	"0"	"1060.2"	"448.1"	"885.7"	"898.3"	"990.7"	"1258.2"	"1194.9"	"1708.4"	"930.7"	"1176.0"	"1885.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43175"	"D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4"	"0.000"	""	"16"	"6"	"15"	"6"	"533"	"56.6"	"6.71"	"3022.94"	"32.92"	"5"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;developmental processes;other biological processes"	"cytosol"	"other molecular function"	"Pf00389, Pf02826, Pf19304"	"26227"	"ENSG00000092621"	"PHGDH"	"B2RD08; hsa:26227; O43175; Q5SZU3; Q9BQ01"	"Serine biosynthesis"	"Trans-sulfuration, one-carbon metabolism and related pathways; Clear cell renal cell carcinoma pathways; Neuroinflammation and glutamatergic signaling; Amino acid metabolism in triple-negative breast cancer cells"	"5"	"0"	"1180.3"	"399.6"	"789.8"	"656.0"	"825.5"	"917.4"	"802.3"	"1158.8"	"1030.1"	"1840.3"	"3589.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11177"	"Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=PDHB PE=1 SV=3"	"0.000"	""	"30"	"8"	"19"	"8"	"359"	"39.2"	"6.65"	"3444.60"	"32.81"	"7"	"8"	"other metabolic processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf02779, Pf02780"	"5162"	"ENSG00000168291"	"PDHB"	"B2R7L0; B4DDD7; hsa:5162; P11177; Q6FH45; Q9BQ27; Q9UFK3"	"Glyoxylate metabolism and glycine degradation; Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid"	"Metabolic reprogramming in colon cancer; Orexin receptor pathway"	"6"	"0"	"925.4"	"453.2"	"943.6"	"773.1"	"890.8"	"1040.8"	"689.5"	"910.3"	"682.3"	"1151.8"	"1885.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15160"	"DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1"	"0.000"	""	"26"	"7"	"15"	"7"	"346"	"39.2"	"5.50"	"2555.35"	"32.78"	"5"	"7"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01000, Pf01193"	"9533"	"ENSG00000171453"	"POLR1C"	"hsa:9533; O15160; O75395; Q5JTE3"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"Pyrimidine metabolism; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"15"	"0"	"308.7"	"132.1"	"283.2"	"240.4"	"266.8"	"287.8"	"237.8"	"543.9"	"1270.4"	"3901.2"	"6530.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P67809"	"Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3"	"0.000"	""	"32"	"7"	"15"	"5"	"324"	"35.9"	"9.88"	"2473.56"	"32.71"	"5"	"7"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00313"	"4904"	"ENSG00000065978"	"YBX1"	"hsa:4904; P16990; P16991; P67809; Q14972; Q15325; Q5FVF0"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Interferon gamma signaling; Noncanonical activation of NOTCH3"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; MECP2 and associated Rett syndrome; mRNA processing; Sudden infant death syndrome (SIDS) susceptibility pathways"	"10"	"2"	"497.6"	"190.8"	"378.5"	"348.5"	"379.0"	"436.6"	"347.8"	"421.6"	"360.0"	"561.1"	"805.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52434"	"DNA-directed RNA polymerases I, II, and III subunit RPABC3 OS=Homo sapiens OX=9606 GN=POLR2H PE=1 SV=4"	"0.000"	""	"37"	"6"	"18"	"6"	"150"	"17.1"	"4.68"	"3406.07"	"32.70"	"6"	"5"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf03870"	"5437"	"ENSG00000163882"	"POLR2H"	"C9J413; C9JBJ6; C9JCU7; C9JUA8; hsa:5437; P52434; P53802; Q969R0"	"mRNA Splicing - Major Pathway; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; Estrogen-dependent gene expression; RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; B-WICH complex positively regulates rRNA expression; Formation of the Early Elongation Complex; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Abortive elongation of HIV-1 transcript in the absence of Tat; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; mRNA Splicing - Minor Pathway; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"57"	"0"	"511.4"	"182.6"	"440.3"	"397.5"	"447.6"	"537.6"	"422.9"	"763.8"	"1158.7"	"3818.5"	"5652.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y383"	"Putative RNA-binding protein Luc7-like 2 OS=Homo sapiens OX=9606 GN=LUC7L2 PE=1 SV=2"	"0.000"	""	"23"	"9"	"18"	"9"	"392"	"46.5"	"10.01"	"3555.16"	"32.70"	"8"	"9"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03194"	"51631"	"ENSG00000146963"	"LUC7L2"	"B7Z500; hsa:51631; Q8IUP9; Q9NVL3; Q9NVN7; Q9UQN1; Q9Y383"	""	""	"0"	"0"	"1403.1"	"437.9"	"887.0"	"750.0"	"878.4"	"1103.7"	"1005.3"	"1543.7"	"1444.6"	"1921.7"	"3037.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WXF1"	"Paraspeckle component 1 OS=Homo sapiens OX=9606 GN=PSPC1 PE=1 SV=1"	"0.000"	""	"15"	"7"	"14"	"6"	"523"	"58.7"	"6.67"	"2069.92"	"32.69"	"6"	"7"	"stress response;other biological processes"	"nucleus;other cell component"	""	"Pf00076, Pf08075"	"55269"	"ENSG00000121390"	"PSPC1"	"hsa:55269; Q5JTQ3; Q8NCZ9; Q8WXE8; Q8WXF1; Q9NV36"	""	""	"0"	"0"	"1036.3"	"403.9"	"922.0"	"702.0"	"888.9"	"1004.1"	"689.5"	"963.6"	"774.1"	"1498.4"	"2347.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P60660"	"Myosin light polypeptide 6 OS=Homo sapiens OX=9606 GN=MYL6 PE=1 SV=2"	"0.000"	""	"44"	"5"	"18"	"4"	"151"	"16.9"	"4.65"	"3329.49"	"32.66"	"5"	"5"	"other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	""	"4637"	"ENSG00000092841"	"MYL6"	"hsa:4637; P16475; P24572; P24573; P60660; Q12790; Q561V9; Q6IAZ0; Q6IPY5"	"RHO GTPases activate CIT; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; Smooth Muscle Contraction; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; RHO GTPases activate PAKs"	"Ciliary landscape"	"8"	"1"	"335.2"	"160.6"	"261.9"	"218.6"	"262.7"	"276.2"	"231.5"	"295.5"	"296.5"	"1124.2"	"2829.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NFP7"	"Diphosphoinositol polyphosphate phosphohydrolase 3-alpha OS=Homo sapiens OX=9606 GN=NUDT10 PE=1 SV=1"	"0.000"	""	"60"	"9"	"17"	"1"	"164"	"18.5"	"5.68"	"2401.84"	"32.65"	"5"	"9"	"other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00293"	"170685"	"ENSG00000122824"	"NUDT10"	"A8K7D7; D3DX69; hsa:170685; Q86VK1; Q86VR0; Q8NFP7"	"Synthesis of pyrophosphates in the cytosol"	""	"1"	"8"	"256.5"	"120.2"	"282.8"	"561.3"	"365.1"	"1231.8"	"1774.0"	"3339.4"	"2489.4"	"5132.0"	"7733.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P06454"	"Prothymosin alpha OS=Homo sapiens OX=9606 GN=PTMA PE=1 SV=2"	"0.000"	""	"23"	"4"	"18"	"4"	"111"	"12.2"	"3.78"	"3686.00"	"32.57"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf03247"	"5757"	"ENSG00000187514"	"PTMA"	"hsa:5757; P06454; Q15249; Q15592"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"599.3"	"341.2"	"521.5"	"489.9"	"571.1"	"599.3"	"547.8"	"569.8"	"497.4"	"604.8"	"831.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00148"	"ATP-dependent RNA helicase DDX39A OS=Homo sapiens OX=9606 GN=DDX39A PE=1 SV=2"	"0.000"	""	"16"	"9"	"22"	"1"	"427"	"49.1"	"5.68"	"3561.14"	"32.50"	"9"	"9"	"RNA metabolism OR transcription;other metabolic processes;transport"	"nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271"	"10212"	"ENSG00000123136"	"DDX39A"	"B1Q2N1; hsa:10212; O00148; Q8N5M0; Q9BVP6; Q9H5W0"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	""	"3"	"0"	"24.5"	"4.9"	"14.4"	"10.1"	"20.4"	"17.6"	"16.1"	"14.6"	"9.6"	"23.7"	"51.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61221"	"ATP-binding cassette sub-family E member 1 OS=Homo sapiens OX=9606 GN=ABCE1 PE=1 SV=1"	"0.000"	""	"19"	"9"	"17"	"9"	"599"	"67.3"	"8.34"	"3939.79"	"32.49"	"9"	"8"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;mitochondrion;translational apparatus;other cell component"	"enzyme regulator activity;translation activity;other molecular function"	"Pf00005, Pf00037, Pf04068"	"6059"	"ENSG00000164163"	"ABCE1"	"hsa:6059; O88793; P61221; Q13181; Q13864; Q6NR76; Q96AL0; Q96B10; Q99K66"	"OAS antiviral response; Interferon alpha/beta signaling"	""	"2"	"0"	"579.3"	"305.0"	"638.3"	"598.5"	"568.1"	"799.2"	"575.1"	"728.7"	"620.5"	"2086.4"	"3959.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43684"	"Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1"	"0.000"	""	"22"	"6"	"19"	"6"	"328"	"37.1"	"6.84"	"3611.61"	"32.48"	"6"	"6"	"cell cycle OR cell proliferation;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00400"	"9184"	"ENSG00000154473"	"BUB3"	"A6NJ42; B2R6E7; D3DRE9; hsa:9184; O43684; O43685"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of mitotic proteins; APC-Cdc20 mediated degradation of Nek2A"	"Cell cycle; Regulation of sister chromatid separation at the metaphase-anaphase transition"	"12"	"0"	"1118.7"	"526.2"	"963.3"	"841.5"	"925.4"	"1080.0"	"780.7"	"1178.9"	"949.9"	"2542.5"	"5980.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15042"	"U2 snRNP-associated SURP motif-containing protein OS=Homo sapiens OX=9606 GN=U2SURP PE=1 SV=2"	"0.000"	""	"13"	"11"	"19"	"10"	"1029"	"118.2"	"8.47"	"3009.14"	"32.38"	"9"	"10"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf00076, Pf01805, Pf04818, Pf08312"	"23350"	"ENSG00000163714"	"U2SURP"	"A0PJ60; hsa:23350; O15042; Q0D2M1; Q2NKQ7; Q9BR70"	"mRNA Splicing - Major Pathway"	""	"1"	"1"	"2031.9"	"633.9"	"1486.3"	"1333.9"	"1469.9"	"1652.7"	"1292.0"	"1836.2"	"1179.2"	"2013.4"	"3754.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60832"	"H/ACA ribonucleoprotein complex subunit DKC1 OS=Homo sapiens OX=9606 GN=DKC1 PE=1 SV=3"	"0.000"	""	"14"	"6"	"15"	"6"	"514"	"57.6"	"9.42"	"3256.94"	"32.23"	"6"	"6"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01472, Pf01509, Pf08068, Pf16198"	"1736"	"ENSG00000130826"	"DKC1"	"F5BSB3; hsa:1736; O43845; O60832; Q96G67; Q9Y505"	"rRNA modification in the nucleus and cytosol; Telomere Extension By Telomerase"	""	"2"	"0"	"560.0"	"222.1"	"478.2"	"460.9"	"483.7"	"610.7"	"434.6"	"562.8"	"546.0"	"2604.8"	"4687.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08579"	"U2 small nuclear ribonucleoprotein B'' OS=Homo sapiens OX=9606 GN=SNRPB2 PE=1 SV=1"	"0.000"	""	"25"	"5"	"20"	"3"	"225"	"25.5"	"9.72"	"2815.29"	"32.09"	"4"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6629"	"ENSG00000125870"	"SNRPB2"	"B2R7J3; D3DW21; hsa:6629; P08579; Q9UJD4"	"mRNA Splicing - Major Pathway"	"mRNA processing; Ciliary landscape"	"3"	"0"	"1199.9"	"594.2"	"955.2"	"854.3"	"932.0"	"970.8"	"762.2"	"953.9"	"671.9"	"953.8"	"1342.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULV4"	"Coronin-1C OS=Homo sapiens OX=9606 GN=CORO1C PE=1 SV=1"	"0.000"	""	"22"	"10"	"22"	"10"	"474"	"53.2"	"7.08"	"4646.77"	"32.01"	"10"	"6"	"cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf08953, Pf16300"	"23603"	"ENSG00000110880"	"CORO1C"	"A7MAP0; A7MAP1; B3KU12; hsa:23603; Q9NSK5; Q9ULV4"	""	""	"0"	"0"	"1597.8"	"631.9"	"1357.7"	"1135.6"	"1260.7"	"1533.9"	"1112.4"	"1627.9"	"1329.4"	"3795.5"	"5357.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61201"	"COP9 signalosome complex subunit 2 OS=Homo sapiens OX=9606 GN=COPS2 PE=1 SV=1"	"0.000"	""	"27"	"9"	"14"	"9"	"443"	"51.6"	"5.53"	"1947.93"	"31.98"	"5"	"9"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01399"	"9318"	"ENSG00000166200"	"COPS2"	"hsa:9318; O88950; P61201; Q15647; Q6FGP4; Q9BY54; Q9R249; Q9UNI2; Q9UNQ5"	"Neddylation; Cargo recognition for clathrin-mediated endocytosis; Formation of TC-NER Pre-Incision Complex; RHOBTB1 GTPase cycle; DNA Damage Recognition in GG-NER"	"Ciliary landscape"	"6"	"0"	"144.2"	"60.0"	"130.3"	"121.0"	"125.8"	"189.5"	"195.3"	"345.3"	"321.4"	"579.5"	"1614.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P98175"	"RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3"	"0.000"	""	"16"	"11"	"17"	"11"	"930"	"103.5"	"5.97"	"3221.36"	"31.94"	"8"	"9"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00641, Pf01585, Pf17780"	"8241"	"ENSG00000182872"	"RBM10"	"A0A0A0MR66; C4AM81; hsa:8241; P98175; Q14136; Q5JRR2; Q9BTE4; Q9BTX0; Q9NTB1"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	""	"2"	"0"	"1107.6"	"436.9"	"1015.3"	"866.7"	"951.5"	"1106.7"	"787.1"	"1048.3"	"814.5"	"1629.2"	"3251.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q2TAY7"	"WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2"	"0.000"	""	"16"	"7"	"18"	"7"	"513"	"57.5"	"7.18"	"3713.51"	"31.86"	"7"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00400, Pf17814"	"55234"	"ENSG00000122692"	"SMU1"	"B4E3L0; hsa:55234; Q2TAY7; Q9BU59; Q9HA96; Q9NVD1"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"929.5"	"278.8"	"602.3"	"525.9"	"612.0"	"740.3"	"553.3"	"757.1"	"726.3"	"1692.9"	"3298.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96T37"	"RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2"	"0.000"	""	"9"	"7"	"16"	"6"	"977"	"107.1"	"10.08"	"2707.78"	"31.83"	"6"	"7"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other membranes;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf07744"	"64783"	"ENSG00000162775"	"RBM15"	"A1A693; hsa:64783; Q3ZB86; Q4V760; Q5D058; Q5T613; Q86VW9; Q96PE4; Q96SC5; Q96SC6; Q96SC9; Q96SD0; Q96T37; Q96T38; Q9BRA5; Q9H6R8; Q9H9Y0"	""	""	"0"	"2"	"656.5"	"198.9"	"440.1"	"384.1"	"429.2"	"517.7"	"515.3"	"1005.9"	"1110.8"	"4025.2"	"6059.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25786"	"Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1"	"0.000"	""	"34"	"8"	"12"	"8"	"263"	"29.5"	"6.61"	"2181.27"	"31.80"	"5"	"7"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00227, Pf10584"	"5682"	"ENSG00000129084"	"PSMA1"	"A8K400; hsa:5682; P25786; Q53YE8; Q9BRV9"	"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"62"	"0"	"754.0"	"328.6"	"709.9"	"706.2"	"681.6"	"858.9"	"699.5"	"883.1"	"729.7"	"1058.8"	"1324.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q00610"	"Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5"	"0.000"	""	"7"	"9"	"20"	"9"	"1675"	"191.5"	"5.69"	"3693.64"	"31.79"	"9"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00637, Pf01394, Pf09268, Pf13838"	"1213"	"ENSG00000141367"	"CLTC"	"D3DU00; hsa:1213; Q00610; Q6N0A0; Q86TF2"	"ALK mutants bind TKIs; Nuclear events stimulated by ALK signaling in cancer; Lysosome Vesicle Biogenesis; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; Formation of annular gap junctions; Recycling pathway of L1; MHC class II antigen presentation; RHOV GTPase cycle; RHOU GTPase cycle; LDL clearance; Retrograde neurotrophin signalling; VLDLR internalisation and degradation; Entry of Influenza Virion into Host Cell via Endocytosis"	"Synaptic vesicle pathway; VEGFA-VEGFR2 signaling; Ebola virus infection in host; Fragile X syndrome; 7q11.23 copy number variation syndrome; Complement and coagulation cascades"	"25"	"0"	"367.1"	"139.3"	"251.3"	"226.3"	"227.1"	"262.0"	"222.9"	"277.1"	"286.0"	"529.7"	"865.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16531"	"DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1"	"0.000"	""	"10"	"10"	"16"	"10"	"1140"	"126.9"	"5.26"	"2182.27"	"31.72"	"6"	"10"	"cell-cell signaling;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03178, Pf10433"	"1642"	"ENSG00000167986"	"DDB1"	"A6NG77; B2R648; B4DG00; hsa:1642; O15176; Q13289; Q16531; Q58F96"	"Neddylation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; DNA Damage Recognition in GG-NER; Dual Incision in GG-NER"	"Hippo-Merlin signaling dysregulation; Hepatitis B infection; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"14"	"0"	"1039.7"	"468.0"	"874.6"	"865.0"	"931.9"	"1027.6"	"894.2"	"1156.1"	"1010.8"	"2477.6"	"5946.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H078"	"Caseinolytic peptidase B protein homolog OS=Homo sapiens OX=9606 GN=CLPB PE=1 SV=1"	"0.000"	""	"15"	"7"	"11"	"7"	"707"	"78.7"	"9.01"	"1973.19"	"31.70"	"4"	"7"	"stress response;signal transduction;other biological processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf07724, Pf10431, Pf12796, Pf13857"	"81570"	"ENSG00000162129"	"CLPB"	"B4DXJ7; B4DXP7; B4DXW4; E7EWN6; F8W7P6; hsa:81570; Q8ND11; Q9H078; Q9H8Y0"	""	""	"0"	"0"	"410.8"	"194.1"	"384.9"	"368.4"	"373.5"	"459.8"	"343.1"	"497.9"	"432.1"	"1292.6"	"3013.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01844"	"RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1"	"0.000"	""	"12"	"6"	"12"	"6"	"656"	"68.4"	"9.33"	"1461.68"	"31.68"	"3"	"6"	"other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00076, Pf00641"	"2130"	"ENSG00000182944"	"EWSR1"	"B0QYK1; hsa:2130; Q01844; Q5THL0; Q92635; Q96FE8; Q96MN4; Q96MX4; Q9BWA2"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"831.9"	"519.2"	"613.1"	"461.3"	"580.3"	"656.8"	"543.4"	"843.1"	"769.0"	"998.7"	"1532.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P57721"	"Poly(rC)-binding protein 3 OS=Homo sapiens OX=9606 GN=PCBP3 PE=1 SV=2"	"0.000"	""	"21"	"7"	"16"	"1"	"371"	"39.4"	"8.07"	"3459.89"	"31.61"	"7"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013"	"54039"	"ENSG00000183570"	"PCBP3"	"A8MPS2; A8MQ26; B7WNN9; B7WPC1; hsa:54039; P57721; Q8N9K6; Q96EP6"	""	""	"0"	"0"	"74.3"	"32.0"	"60.9"	"49.1"	"55.3"	"70.4"	"57.5"	"78.2"	"57.2"	"157.8"	"234.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P83731"	"60S ribosomal protein L24 OS=Homo sapiens OX=9606 GN=RPL24 PE=1 SV=1"	"0.000"	""	"41"	"8"	"21"	"8"	"157"	"17.8"	"11.25"	"3888.53"	"31.52"	"8"	"7"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01246"	"6152"	"ENSG00000114391"	"RPL24"	"B2R4Y3; hsa:6152; P38663; P83731; Q6IBS3"	"Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Peptide chain elongation; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"1460.4"	"650.8"	"1372.7"	"1288.8"	"1243.9"	"1545.8"	"1106.8"	"1422.8"	"1047.4"	"1863.7"	"2486.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96KP1"	"Exocyst complex component 2 OS=Homo sapiens OX=9606 GN=EXOC2 PE=1 SV=1"	"0.000"	""	"10"	"9"	"19"	"8"	"924"	"104.0"	"6.90"	"3062.47"	"31.47"	"8"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf01833, Pf15469"	"55770"	"ENSG00000112685"	"EXOC2"	"B2RBE6; hsa:55770; Q5JPC8; Q96AN6; Q96KP1; Q9NUZ8; Q9UJM7"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"RalA downstream regulated genes; Chromosomal and microsatellite instability in colorectal cancer ; Ras signaling; Ciliary landscape"	"7"	"1"	"389.7"	"145.4"	"325.1"	"280.0"	"330.3"	"387.6"	"324.1"	"477.2"	"542.3"	"1614.6"	"3055.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23193"	"Transcription elongation factor A protein 1 OS=Homo sapiens OX=9606 GN=TCEA1 PE=1 SV=2"	"0.000"	""	"23"	"8"	"19"	"8"	"301"	"33.9"	"8.38"	"2682.18"	"31.39"	"6"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01096, Pf07500, Pf08711"	"6917"	"ENSG00000187735"	"TCEA1"	"A6NF25; A8K339; hsa:6917; P23193; Q15563; Q6FG87"	"Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	""	"15"	"0"	"347.5"	"197.7"	"347.8"	"304.7"	"353.7"	"409.2"	"311.5"	"397.0"	"362.2"	"1568.3"	"3972.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43143"	"Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2"	"0.000"	""	"11"	"8"	"18"	"8"	"795"	"90.9"	"7.46"	"3846.55"	"31.39"	"8"	"6"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"1665"	"ENSG00000109606"	"DHX15"	"hsa:1665; O43143; Q9NQT7"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"0"	"822.1"	"251.7"	"533.5"	"459.3"	"582.2"	"610.3"	"516.6"	"689.1"	"612.9"	"1194.9"	"2068.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60256"	"Phosphoribosyl pyrophosphate synthase-associated protein 2 OS=Homo sapiens OX=9606 GN=PRPSAP2 PE=1 SV=1"	"0.000"	""	"21"	"7"	"18"	"7"	"369"	"40.9"	"7.44"	"3168.95"	"31.36"	"7"	"7"	"other metabolic processes;developmental processes"	"other cell component"	"enzyme regulator activity;other molecular function"	"Pf13793, Pf14572"	"5636"	"ENSG00000141127"	"PRPSAP2"	"B4E1M8; B4E329; B7ZKZ1; E7EMY2; hsa:5636; O60256; Q6IAS2"	""	""	"0"	"0"	"334.3"	"140.5"	"296.4"	"233.4"	"302.4"	"355.8"	"289.3"	"485.2"	"632.1"	"2313.7"	"5844.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UNX4"	"WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1"	"0.000"	""	"10"	"7"	"10"	"7"	"943"	"106.0"	"6.64"	"1307.72"	"31.31"	"3"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00400, Pf04003, Pf12894"	"10885"	"ENSG00000065183"	"WDR3"	"hsa:10885; Q9UNX4"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	"219.1"	"103.1"	"204.8"	"189.6"	"201.5"	"246.4"	"186.6"	"272.2"	"401.3"	"1920.2"	"3381.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96I25"	"Splicing factor 45 OS=Homo sapiens OX=9606 GN=RBM17 PE=1 SV=1"	"0.000"	""	"21"	"9"	"21"	"8"	"401"	"44.9"	"5.97"	"3806.85"	"31.31"	"9"	"8"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf01585"	"84991"	"ENSG00000134453"	"RBM17"	"hsa:84991; Q96GY6; Q96I25"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"1"	"1279.6"	"533.1"	"934.3"	"846.6"	"990.1"	"1165.4"	"970.4"	"1259.7"	"1023.9"	"1717.5"	"3083.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P67870"	"Casein kinase II subunit beta OS=Homo sapiens OX=9606 GN=CSNK2B PE=1 SV=1"	"0.000"	""	"27"	"6"	"14"	"6"	"215"	"24.9"	"5.55"	"3070.67"	"31.17"	"6"	"6"	"cell-cell signaling;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;kinase activity;other molecular function"	"Pf01214"	"1460"	"ENSG00000204435; ENSG00000206406; ENSG00000224398; ENSG00000224774; ENSG00000228875; ENSG00000230700; ENSG00000232960"	"CSNK2B"	"B0UXA9; hsa:1460; P07312; P13862; P67870; Q4VX47"	"Neutrophil degranulation; Condensation of Prometaphase Chromosomes; Regulation of PTEN stability and activity; KEAP1-NFE2L2 pathway; Regulation of TP53 Activity through Phosphorylation; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; WNT mediated activation of DVL; Signal transduction by L1; Receptor Mediated Mitophagy; Synthesis of PC"	"Alzheimer's disease and miRNA effects; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Measles virus infection; Pleural mesothelioma; Alzheimer's disease"	"19"	"0"	"567.8"	"287.4"	"704.6"	"615.3"	"629.3"	"843.1"	"618.3"	"878.1"	"608.8"	"1052.2"	"2312.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WYA6"	"Beta-catenin-like protein 1 OS=Homo sapiens OX=9606 GN=CTNNBL1 PE=1 SV=1"	"0.000"	""	"14"	"10"	"19"	"10"	"563"	"65.1"	"5.05"	"2768.65"	"31.04"	"7"	"10"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf08216"	"56259"	"ENSG00000132792"	"CTNNBL1"	"B4DE16; hsa:56259; Q0VAL9; Q0VAM0; Q53HI8; Q5JWZ2; Q5JWZ3; Q5JWZ7; Q5JWZ8; Q8N454; Q8NCL2; Q8TBD6; Q8WYA6; Q96KD2; Q9H7A5; Q9NQF9; Q9NTX0; Q9Y3M7"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"949.5"	"453.9"	"902.1"	"822.5"	"876.7"	"1111.9"	"844.6"	"1012.0"	"706.3"	"2236.8"	"6814.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18583"	"Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4"	"0.000"	""	"3"	"7"	"17"	"7"	"2426"	"263.7"	"5.64"	"2895.00"	"31.00"	"6"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf01585, Pf14709, Pf17069"	"6651"	"ENSG00000159140"	"SON"	"D3DSF5; D3DSF6; E7ETE8; E7EU67; E7EVW3; E9PFQ2; hsa:6651; O14487; O95981; P18583; Q14120; Q6PKE0; Q9H7B1; Q9P070; Q9P072; Q9UKP9; Q9UPY0"	""	""	"0"	"0"	"649.6"	"193.2"	"365.7"	"304.7"	"382.5"	"423.8"	"363.1"	"531.3"	"473.9"	"1040.7"	"2047.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63241"	"Eukaryotic translation initiation factor 5A-1 OS=Homo sapiens OX=9606 GN=EIF5A PE=1 SV=2"	"0.000"	""	"48"	"5"	"13"	"5"	"154"	"16.8"	"5.24"	"1275.43"	"30.85"	"4"	"4"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf01287"	"1984"	"ENSG00000132507; ENSG00000288145"	"EIF5A"	"A8K9A0; D3DTP2; hsa:1984; P10159; P63241; Q16182; Q7L7L3; Q7Z4L1; Q9D0G2"	"Hypusine synthesis from eIF5A-lysine"	"Translation factors; eIF5A regulation in response to inhibition of the nuclear export system"	"3"	"0"	"805.6"	"407.8"	"600.1"	"536.7"	"618.1"	"744.1"	"667.2"	"755.1"	"802.0"	"2152.6"	"11875.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01130"	"Serine/arginine-rich splicing factor 2 OS=Homo sapiens OX=9606 GN=SRSF2 PE=1 SV=4"	"0.000"	""	"15"	"3"	"15"	"3"	"221"	"25.5"	"11.85"	"4057.91"	"30.84"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00076"	"6427"	"ENSG00000161547"	"SRSF2"	"B3KWD5; B4DN89; H0YG49; hsa:6427; Q01130"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Minor Pathway"	"mRNA processing"	"7"	"0"	"923.1"	"376.1"	"636.9"	"602.5"	"619.8"	"748.8"	"768.3"	"1038.6"	"689.3"	"694.1"	"679.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05141"	"ADP/ATP translocase 2 OS=Homo sapiens OX=9606 GN=SLC25A5 PE=1 SV=7"	"0.000"	""	"23"	"7"	"20"	"2"	"298"	"32.8"	"9.69"	"3423.10"	"30.78"	"7"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;mitochondrion"	"transporter activity;other molecular function"	"Pf00153"	"292"	"ENSG00000005022"	"SLC25A5"	"B2RCV1; hsa:292; O43350; P05141"	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane; Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization"	"Electron transport chain: OXPHOS system in mitochondria; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"5"	"5"	"1206.5"	"432.1"	"968.5"	"839.8"	"865.1"	"1093.7"	"879.8"	"1113.0"	"973.7"	"2122.8"	"5176.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62304"	"Small nuclear ribonucleoprotein E OS=Homo sapiens OX=9606 GN=SNRPE PE=1 SV=1"	"0.000"	""	"65"	"4"	"16"	"4"	"92"	"10.8"	"9.44"	"2411.05"	"30.77"	"3"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	"6635"	"ENSG00000182004"	"SNRPE"	"B2R5B9; hsa:6635; P08578; P62304; Q15498; Q5BKT2"	"mRNA Splicing - Major Pathway; SARS-CoV-2 modulates host translation machinery; snRNP Assembly; RNA Polymerase II Transcription Termination; mRNA Splicing - Minor Pathway; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"mRNA processing"	"8"	"0"	"547.9"	"213.4"	"374.7"	"342.2"	"436.4"	"502.6"	"395.5"	"558.1"	"463.3"	"667.4"	"872.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61160"	"Actin-related protein 2 OS=Homo sapiens OX=9606 GN=ACTR2 PE=1 SV=1"	"0.000"	""	"28"	"8"	"14"	"8"	"394"	"44.7"	"6.74"	"1714.72"	"30.69"	"5"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00022"	"10097"	"ENSG00000138071"	"ACTR2"	"B2RCP5; D6W5F4; E9PF41; hsa:10097; O15142; P61160; Q96C82"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Neutrophil degranulation; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"Physico-chemical features and toxicity-associated pathways; Embryonic stem cell pluripotency pathways"	"8"	"0"	"343.2"	"147.9"	"270.1"	"217.1"	"282.6"	"286.3"	"262.4"	"351.6"	"349.9"	"1427.5"	"4166.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q4VCS5"	"Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1"	"0.000"	""	"10"	"11"	"19"	"9"	"1084"	"118.0"	"7.64"	"2570.90"	"30.67"	"9"	"10"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf12240"	"154796"	"ENSG00000126016"	"AMOT"	"hsa:154796; Q4VCS5; Q504X5; Q9HD27; Q9UPT1"	""	"VEGFA-VEGFR2 signaling; Hippo-Merlin signaling dysregulation; Pleural mesothelioma"	"3"	"1"	"1666.9"	"608.4"	"1071.4"	"931.2"	"1085.5"	"1137.5"	"818.9"	"1198.2"	"946.6"	"2067.1"	"3912.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62241"	"40S ribosomal protein S8 OS=Homo sapiens OX=9606 GN=RPS8 PE=1 SV=2"	"0.000"	""	"32"	"8"	"19"	"8"	"208"	"24.2"	"10.32"	"3007.83"	"30.66"	"7"	"8"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01201"	"6202"	"ENSG00000142937"	"RPS8"	"hsa:6202; P09058; P62241; Q6IRL7"	"Major pathway of rRNA processing in the nucleolus and cytosol; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Selenocysteine synthesis; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"1615.5"	"857.5"	"1337.5"	"1276.3"	"1303.4"	"1513.2"	"1183.4"	"1568.5"	"1185.3"	"2258.1"	"3490.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15344"	"E3 ubiquitin-protein ligase Midline-1 OS=Homo sapiens OX=9606 GN=MID1 PE=1 SV=1"	"0.000"	""	"12"	"6"	"10"	"6"	"667"	"75.2"	"6.80"	"1243.51"	"30.65"	"3"	"6"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00041, Pf00622, Pf00643, Pf13445, Pf13765, Pf18568"	"4281"	"ENSG00000101871"	"MID1"	"B2RCG2; hsa:4281; O15344; O75361; Q9BZX5"	"Interferon gamma signaling"	""	"1"	"0"	"186.4"	"79.9"	"170.4"	"155.9"	"174.3"	"208.0"	"170.6"	"319.6"	"358.2"	"1539.5"	"3399.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N1F7"	"Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2"	"0.000"	""	"12"	"8"	"19"	"8"	"819"	"93.4"	"5.72"	"3538.71"	"30.38"	"8"	"8"	"cell organization and biogenesis;other metabolic processes;transport;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus"	"other molecular function"	"Pf04097"	"9688"	"ENSG00000102900"	"NUP93"	"B3KPQ8; hsa:9688; Q14705; Q8N1F7"	"SUMOylation of DNA replication proteins; Regulation of HSF1-mediated heat shock response; HCMV Early Events; Transport of Mature mRNA derived from an Intron-Containing Transcript; HCMV Late Events; Transcriptional regulation by small RNAs; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Postmitotic nuclear pore complex (NPC) reformation"	""	"29"	"0"	"928.2"	"399.1"	"931.8"	"803.6"	"864.3"	"1015.6"	"694.9"	"902.0"	"710.3"	"1370.3"	"2083.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P45973"	"Chromobox protein homolog 5 OS=Homo sapiens OX=9606 GN=CBX5 PE=1 SV=1"	"0.000"	""	"32"	"5"	"15"	"4"	"191"	"22.2"	"5.86"	"3238.57"	"30.22"	"5"	"5"	"cell organization and biogenesis;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00385, Pf01393"	"23468"	"ENSG00000094916"	"CBX5"	"B2R8T9; hsa:23468; P45973"	"SUMOylation of chromatin organization proteins; Transcriptional Regulation by E2F6; Factors involved in megakaryocyte development and platelet production"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; 22q11.2 copy number variation syndrome"	"5"	"0"	"792.2"	"365.3"	"662.1"	"719.9"	"749.8"	"1252.7"	"1600.3"	"2715.1"	"1718.7"	"1305.3"	"1871.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P40222"	"Alpha-taxilin OS=Homo sapiens OX=9606 GN=TXLNA PE=1 SV=3"	"0.000"	""	"18"	"8"	"11"	"8"	"546"	"61.9"	"6.52"	"1564.06"	"30.20"	"3"	"8"	"transport;other biological processes"	"non-structural extracellular;cytosol;other cell component"	"other molecular function"	"Pf09728"	"200081"	"ENSG00000084652"	"TXLNA"	"D3DPP6; hsa:200081; P40222; Q5TFJ6; Q66K62; Q86T54; Q86T85; Q86T86; Q86Y86; Q86YW3; Q8N2Y3"	"Other interleukin signaling"	""	"1"	"0"	"357.9"	"143.0"	"297.1"	"263.4"	"306.4"	"330.7"	"237.5"	"385.9"	"380.1"	"1854.4"	"3970.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BRP8"	"Partner of Y14 and mago OS=Homo sapiens OX=9606 GN=PYM1 PE=1 SV=1"	"0.000"	""	"42"	"6"	"16"	"6"	"204"	"22.6"	"9.45"	"2731.62"	"30.15"	"6"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity"	"Pf09282"	"84305"	"ENSG00000170473"	"PYM1"	"B6ZDM5; hsa:84305; Q8IXJ8; Q8N8E7; Q9BRP8"	""	"TAR syndrome"	"1"	"0"	"247.6"	"117.7"	"236.6"	"220.5"	"247.9"	"281.3"	"210.8"	"336.8"	"318.8"	"1070.8"	"2101.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42167"	"Lamina-associated polypeptide 2, isoforms beta/gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2"	"0.000"	""	"27"	"9"	"15"	"9"	"454"	"50.6"	"9.38"	"2129.04"	"30.11"	"7"	"8"	""	"other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03020, Pf08198"	"7112"	"ENSG00000120802"	"TMPO"	"A2T926; hsa:7112; P42167; Q14861"	"RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOJ GTPase cycle; RHOG GTPase cycle; RHOD GTPase cycle; RHOF GTPase cycle"	"Envelope proteins and their potential roles in EDMD physiopathology; Overlap between signal transduction pathways contributing to LMNA laminopathies"	"12"	"0"	"1291.8"	"503.2"	"891.1"	"774.6"	"939.1"	"1024.8"	"753.6"	"1135.9"	"906.1"	"1726.5"	"3544.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75390"	"Citrate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=CS PE=1 SV=2"	"0.000"	""	"18"	"8"	"20"	"8"	"466"	"51.7"	"8.32"	"3931.18"	"30.10"	"8"	"8"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00285"	"1431"	"ENSG00000062485"	"CS"	"hsa:1431; O75390; Q71UT9; Q7KZH0; Q96FZ8; Q9BWN8"	"Citric acid cycle (TCA cycle); Mitochondrial protein import"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Fluoroacetic acid toxicity; TCA cycle (aka Krebs or citric acid cycle)"	"6"	"0"	"1507.6"	"815.1"	"1711.9"	"1412.0"	"1553.9"	"1780.9"	"1208.0"	"1417.1"	"985.6"	"1800.2"	"3099.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P06576"	"ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3"	"0.000"	""	"16"	"6"	"16"	"6"	"529"	"56.5"	"5.40"	"3396.93"	"30.05"	"6"	"6"	"other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"signal transduction activity or receptor binding;transporter activity;other molecular function"	"Pf00006, Pf02874"	"506"	"ENSG00000110955"	"ATP5F1B"	"A8K4X0; hsa:506; P06576; Q14283"	"Transcriptional activation of mitochondrial biogenesis; Mitochondrial protein import; Cristae formation; Formation of ATP by chemiosmotic coupling"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"7"	"0"	"471.7"	"181.8"	"343.4"	"278.2"	"345.8"	"398.5"	"354.0"	"491.7"	"459.1"	"960.0"	"1695.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12955"	"Ankyrin-3 OS=Homo sapiens OX=9606 GN=ANK3 PE=1 SV=3"	"0.000"	""	"3"	"10"	"19"	"10"	"4377"	"480.1"	"6.49"	"2835.63"	"29.64"	"9"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00531, Pf00791, Pf12796, Pf17809"	"288"	"ENSG00000151150"	"ANK3"	"B1AQT2; B4DIL1; E9PE32; hsa:288; Q12955; Q13484; Q5CZH9; Q5VXD5; Q7Z3G4; Q9H0P5"	"COPI-mediated anterograde transport; Interaction between L1 and Ankyrins"	"Splicing factor NOVA regulated synaptic proteins"	"3"	"0"	"986.9"	"412.2"	"950.1"	"771.7"	"863.7"	"1033.8"	"693.5"	"859.7"	"663.0"	"1312.5"	"2397.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q08170"	"Serine/arginine-rich splicing factor 4 OS=Homo sapiens OX=9606 GN=SRSF4 PE=1 SV=2"	"0.000"	""	"13"	"7"	"18"	"3"	"494"	"56.6"	"11.52"	"2740.54"	"29.60"	"7"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"6429"	"ENSG00000116350"	"SRSF4"	"hsa:6429; Q08170; Q5VXP1; Q9BUA4; Q9UEB5"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"mRNA processing"	"6"	"0"	"416.8"	"140.0"	"297.4"	"286.5"	"299.6"	"380.2"	"401.5"	"575.4"	"425.3"	"575.9"	"824.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14868"	"Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2"	"0.000"	""	"20"	"8"	"14"	"8"	"501"	"57.1"	"6.55"	"2175.10"	"29.25"	"5"	"8"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00152, Pf01336"	"1615"	"ENSG00000115866"	"DARS1"	"A8K3J2; D3DP77; hsa:1615; P14868; Q2TNI3; Q32Q69; Q53HV4; Q53YC5; Q68CR9; Q9BW52"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"Alanine and aspartate metabolism"	"3"	"0"	"260.3"	"98.7"	"221.8"	"201.0"	"217.4"	"234.5"	"194.3"	"257.7"	"206.7"	"725.1"	"2943.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62857"	"40S ribosomal protein S28 OS=Homo sapiens OX=9606 GN=RPS28 PE=1 SV=1"	"0.000"	""	"68"	"6"	"17"	"6"	"69"	"7.8"	"10.70"	"3996.88"	"29.19"	"6"	"6"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01200"	"6234"	"ENSG00000233927"	"RPS28"	"hsa:6234; P25112; P62857"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"952.7"	"480.1"	"896.1"	"781.9"	"853.5"	"1009.6"	"737.5"	"966.2"	"769.5"	"1206.1"	"1616.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95208"	"Epsin-2 OS=Homo sapiens OX=9606 GN=EPN2 PE=1 SV=3"	"0.000"	""	"14"	"8"	"19"	"8"	"641"	"68.4"	"7.52"	"2876.76"	"29.17"	"7"	"8"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01417"	"22905"	"ENSG00000072134"	"EPN2"	"A8MTV8; B3KRX8; E9PBC2; hsa:22905; O95207; O95208; Q52LD0; Q9H7Z2; Q9UPT7"	"Cargo recognition for clathrin-mediated endocytosis"	""	"2"	"0"	"199.7"	"105.0"	"241.3"	"411.3"	"317.3"	"868.5"	"804.7"	"1463.4"	"1041.3"	"1940.7"	"2406.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96AG4"	"Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1"	"0.000"	""	"22"	"6"	"17"	"6"	"307"	"34.9"	"9.57"	"2600.57"	"29.08"	"5"	"6"	""	"other membranes;mitochondrion;ER/Golgi;nucleus;other cell component"	""	"Pf13855"	"55379"	"ENSG00000108829"	"LRRC59"	"B2RE83; D3DTX8; hsa:55379; Q96AG4; Q9P189"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"474.4"	"198.1"	"394.8"	"328.3"	"334.1"	"478.3"	"335.8"	"538.6"	"485.1"	"1453.3"	"3063.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75934"	"Pre-mRNA-splicing factor SPF27 OS=Homo sapiens OX=9606 GN=BCAS2 PE=1 SV=1"	"0.000"	""	"22"	"6"	"12"	"6"	"225"	"26.1"	"5.66"	"1958.91"	"29.05"	"4"	"6"	"RNA metabolism OR transcription;other metabolic processes"	"cytoskeleton;nucleus;other cell component"	""	"Pf05700"	"10286"	"ENSG00000116752"	"BCAS2"	"hsa:10286; O75934; Q6FGS0"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"288.5"	"108.4"	"197.8"	"159.4"	"202.5"	"227.9"	"175.4"	"229.2"	"227.9"	"1234.1"	"4563.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26373"	"60S ribosomal protein L13 OS=Homo sapiens OX=9606 GN=RPL13 PE=1 SV=4"	"0.000"	""	"36"	"9"	"16"	"9"	"211"	"24.2"	"11.65"	"2576.52"	"29.00"	"7"	"8"	"protein metabolism;other metabolic processes;developmental processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01294"	"6137"	"ENSG00000167526"	"RPL13"	"B4DLX3; F5H1S2; hsa:6137; P26373; Q3KQT8; Q567Q8; Q9BPX0"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"2368.8"	"1041.6"	"2124.9"	"1869.9"	"1982.8"	"2266.8"	"1657.7"	"2125.9"	"1592.4"	"2828.4"	"3652.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P2J5"	"Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2"	"0.000"	""	"10"	"9"	"22"	"9"	"1176"	"134.4"	"7.30"	"3376.79"	"28.96"	"9"	"7"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00133, Pf08264"	"51520"	"ENSG00000133706"	"LARS1"	"A2RRR4; A7E266; B4DJ10; hsa:51520; Q2TU79; Q9NSE1; Q9P2J5"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	""	"2"	"0"	"551.5"	"243.7"	"503.5"	"408.0"	"483.0"	"529.7"	"423.5"	"543.9"	"434.6"	"997.0"	"2046.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61158"	"Actin-related protein 3 OS=Homo sapiens OX=9606 GN=ACTR3 PE=1 SV=3"	"0.000"	""	"18"	"6"	"13"	"6"	"418"	"47.3"	"5.88"	"2459.86"	"28.92"	"5"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00022"	"10096"	"ENSG00000115091"	"ACTR3"	"hsa:10096; P32391; P61158; Q53QM2"	"EPHB-mediated forward signaling; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis"	"Physico-chemical features and toxicity-associated pathways"	"6"	"0"	"320.2"	"136.8"	"273.4"	"258.2"	"266.4"	"326.1"	"265.0"	"317.6"	"360.4"	"2247.2"	"7071.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P29692"	"Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5"	"0.000"	""	"29"	"9"	"20"	"6"	"281"	"31.1"	"5.01"	"4674.92"	"28.88"	"9"	"6"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00736, Pf10587"	"1936"	"ENSG00000104529; ENSG00000273594"	"EEF1D"	"B4DDU4; D3DWK3; E9PBQ9; hsa:1936; P29692; Q4VBZ6; Q969J1; Q96I38"	"Eukaryotic Translation Elongation"	"Translation factors"	"2"	"0"	"952.4"	"381.5"	"905.3"	"755.8"	"855.7"	"1084.0"	"687.4"	"862.7"	"669.5"	"1293.5"	"2317.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62249"	"40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2"	"0.000"	""	"49"	"8"	"20"	"8"	"146"	"16.4"	"10.21"	"3469.49"	"28.87"	"7"	"8"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00380"	"6217"	"ENSG00000105193"	"RPS16"	"B2RDD5; hsa:6217; P17008; P62249"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"1781.9"	"913.8"	"1537.5"	"1381.2"	"1466.2"	"1842.2"	"1376.2"	"1671.0"	"1443.7"	"2013.6"	"3133.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NR30"	"Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5"	"0.000"	""	"12"	"8"	"15"	"7"	"783"	"87.3"	"9.28"	"2712.52"	"28.84"	"7"	"8"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf08152"	"9188"	"ENSG00000165732"	"DDX21"	"B2RDL0; hsa:9188; Q13436; Q5VX41; Q68D35; Q9NR30"	"B-WICH complex positively regulates rRNA expression; Major pathway of rRNA processing in the nucleolus and cytosol"	"10q11.21q11.23 copy number variation syndrome"	"3"	"1"	"566.0"	"203.4"	"417.7"	"348.2"	"422.4"	"468.9"	"358.5"	"474.3"	"410.6"	"905.6"	"2269.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53621"	"Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2"	"0.000"	""	"9"	"10"	"19"	"10"	"1224"	"138.3"	"7.66"	"2796.13"	"28.82"	"8"	"9"	"transport;signal transduction"	"non-structural extracellular;other membranes;cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00400, Pf04053, Pf06957, Pf12894"	"1314"	"ENSG00000122218"	"COPA"	"hsa:1314; P53621; Q5T201; Q8IXZ9"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport"	""	"2"	"0"	"1096.2"	"530.9"	"1056.1"	"922.9"	"948.5"	"1146.3"	"835.2"	"1017.2"	"796.7"	"1548.7"	"2817.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99986"	"Serine/threonine-protein kinase VRK1 OS=Homo sapiens OX=9606 GN=VRK1 PE=1 SV=1"	"0.000"	""	"20"	"8"	"15"	"8"	"396"	"45.4"	"8.91"	"2577.19"	"28.78"	"6"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;ER/Golgi;nucleus"	"kinase activity;other molecular function"	"Pf00069"	"7443"	"ENSG00000100749"	"VRK1"	"hsa:7443; Q3SYL2; Q99986"	"Initiation of Nuclear Envelope (NE) Reformation; Nuclear Envelope Breakdown"	""	"2"	"0"	"859.3"	"287.2"	"767.0"	"581.3"	"722.3"	"890.7"	"521.4"	"901.7"	"782.5"	"4797.3"	"9364.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BY44"	"Eukaryotic translation initiation factor 2A OS=Homo sapiens OX=9606 GN=EIF2A PE=1 SV=3"	"0.000"	""	"17"	"8"	"12"	"8"	"585"	"64.9"	"8.87"	"2099.76"	"28.77"	"5"	"7"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;translational apparatus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf08662"	"83939"	"ENSG00000144895"	"EIF2A"	"A8MPS6; B4DF96; B4DQ14; D3DNI9; hsa:83939; Q5QTR2; Q7Z4E9; Q8NFM1; Q96EW9; Q96K81; Q9BY44"	""	"Photodynamic therapy-induced unfolded protein response; VEGFA-VEGFR2 signaling; 7q11.23 copy number variation syndrome"	"3"	"0"	"505.8"	"233.5"	"464.7"	"430.3"	"487.2"	"517.9"	"424.3"	"570.4"	"496.3"	"2290.4"	"5285.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14776"	"Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2"	"0.000"	""	"6"	"7"	"12"	"7"	"1098"	"123.8"	"8.65"	"1310.50"	"28.76"	"4"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00397, Pf01846"	"10915"	"ENSG00000113649"	"TCERG1"	"hsa:10915; O14776; Q2NKN2; Q59EA1"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"699.9"	"325.2"	"557.0"	"448.9"	"533.1"	"595.5"	"430.5"	"618.8"	"513.1"	"1237.3"	"2689.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NV70"	"Exocyst complex component 1 OS=Homo sapiens OX=9606 GN=EXOC1 PE=1 SV=4"	"0.000"	""	"12"	"8"	"13"	"8"	"894"	"101.9"	"6.61"	"1912.25"	"28.69"	"5"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf09763, Pf15277"	"55763"	"ENSG00000090989"	"EXOC1"	"hsa:55763; Q504V4; Q8WUE7; Q96T15; Q9NV70; Q9NZE4"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"Ciliary landscape"	"4"	"0"	"323.5"	"128.2"	"289.0"	"260.5"	"309.3"	"508.7"	"592.4"	"1353.7"	"1362.6"	"2999.5"	"3905.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13151"	"Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1"	"0.000"	""	"17"	"5"	"22"	"3"	"305"	"30.8"	"9.29"	"3768.67"	"28.68"	"5"	"4"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"10949"	"ENSG00000177733"	"HNRNPA0"	"hsa:10949; Q13151; Q6IB18"	""	""	"0"	"0"	"1074.8"	"318.7"	"668.7"	"536.0"	"653.4"	"696.9"	"523.4"	"781.9"	"628.4"	"1031.1"	"1558.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5S9"	"RNA-binding protein 8A OS=Homo sapiens OX=9606 GN=RBM8A PE=1 SV=1"	"0.000"	""	"17"	"2"	"12"	"2"	"174"	"19.9"	"5.72"	"4895.31"	"28.63"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"9939"	"ENSG00000265241"	"RBM8A"	"B3KQI9; hsa:9939; Q6FHD1; Q6IQ40; Q9GZX8; Q9NZI4; Q9Y5S9"	"mRNA Splicing - Major Pathway; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript"	""	"6"	"0"	"345.7"	"104.3"	"158.4"	"140.4"	"176.0"	"174.8"	"176.0"	"213.7"	"196.2"	"325.4"	"696.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14644"	"Ras GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=RASA3 PE=1 SV=3"	"0.000"	""	"12"	"10"	"20"	"10"	"834"	"95.6"	"7.15"	"2842.83"	"28.60"	"9"	"10"	"transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol"	"transporter activity;enzyme regulator activity;other molecular function"	"Pf00168, Pf00169, Pf00616, Pf00779"	"22821"	"ENSG00000185989; ENSG00000280477"	"RASA3"	"A6NL15; F8W6X8; hsa:22821; Q14644; Q8IUY2"	"Regulation of RAS by GAPs"	"MAPK cascade; Ras signaling; IL-18 signaling pathway"	"4"	"0"	"663.6"	"339.8"	"672.2"	"621.9"	"691.0"	"813.4"	"690.9"	"1056.0"	"1309.9"	"3968.4"	"4650.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11940"	"Polyadenylate-binding protein 1 OS=Homo sapiens OX=9606 GN=PABPC1 PE=1 SV=2"	"0.000"	""	"13"	"8"	"19"	"5"	"636"	"70.6"	"9.50"	"2919.92"	"28.53"	"7"	"8"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf00658"	"26986"	"ENSG00000070756"	"PABPC1"	"hsa:26986; P11940; Q15097; Q93004"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; AUF1 (hnRNP D0) binds and destabilizes mRNA; Regulation of expression of SLITs and ROBOs; Deadenylation of mRNA; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Translation factors; Endoderm differentiation; VEGFA-VEGFR2 signaling; Acute viral myocarditis"	"11"	"3"	"1786.1"	"676.9"	"1442.3"	"1233.9"	"1373.3"	"1568.8"	"1190.9"	"1675.0"	"1358.8"	"2503.7"	"4119.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55884"	"Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3"	"0.000"	""	"15"	"8"	"13"	"8"	"814"	"92.4"	"5.00"	"1977.80"	"28.50"	"6"	"7"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08662"	"8662"	"ENSG00000106263"	"EIF3B"	"A4D208; hsa:8662; P55884; Q2NL77; Q9UMF9"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"8"	"0"	"554.3"	"216.5"	"526.0"	"479.4"	"520.1"	"646.4"	"462.5"	"607.4"	"457.8"	"1144.4"	"2643.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P31948"	"Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1"	"0.000"	""	"19"	"9"	"17"	"9"	"543"	"62.6"	"6.80"	"3179.34"	"28.48"	"8"	"7"	"other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00515, Pf13181, Pf17830"	"10963"	"ENSG00000168439"	"STIP1"	"B4DM70; F5H0T1; G3XAD8; hsa:10963; P31948; Q3ZCU9; Q5TZU9"	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; RND1 GTPase cycle"	"VEGFA-VEGFR2 signaling"	"3"	"0"	"1799.7"	"740.2"	"1241.5"	"1021.1"	"1335.4"	"1430.8"	"1161.5"	"1441.4"	"1337.5"	"2189.6"	"3788.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62979"	"Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2"	"0.000"	""	"56"	"8"	"17"	"8"	"156"	"18.0"	"9.64"	"2904.48"	"28.44"	"6"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;translational apparatus;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00240, Pf01599"	"6233"	"ENSG00000143947"	"RPS27A"	"hsa:6233; P02248; P02249; P02250; P14798; P62979; P62988; Q29120; Q6LBL4; Q6LDU5; Q8WYN8; Q91887; Q91888; Q9BQ77; Q9BWD6; Q9BX98; Q9UEF2; Q9UEG1; Q9UEK8; Q9UPK7"	"Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Aggrephagy; Oxidative Stress Induced Senescence; ISG15 antiviral mechanism; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; InlA-mediated entry of Listeria monocytogenes into host cells; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Orc1 removal from chromatin; Assembly of the pre-replicative complex; Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; Recognition of DNA damage by PCNA-containing replication complex; Dual Incision in GG-NER; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER; Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation; Negative regulation of MET activity; InlB-mediated entry of Listeria monocytogenes into host cell; Peroxisomal protein import; Degradation of GLI1 by the proteasome; Hedgehog 'on' state; Activated NOTCH1 Transmits Signal to the Nucleus; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Regulation of PLK1 Activity at G2/M Transition; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery; E3 ubiquitin ligases ubiquitinate target proteins; Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Stimuli-sensing channels; Amyloid fiber formation; Fanconi Anemia Pathway; Budding and maturation of HIV virion; Membrane binding and targetting of GAG proteins; Endosomal Sorting Complex Required For Transport (ESCRT); Late endosomal microautophagy; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; NOTCH2 Activation and Transmission of Signal to the Nucleus; NOTCH3 Activation and Transmission of Signal to the Nucleus; Regulation of TP53 Degradation; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Activation of IRF3, IRF7 mediated by TBK1, IKBKE; IKK complex recruitment mediated by RIP1; TRAF6-mediated induction of TAK1 complex within TLR4 complex; IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation; ER Quality Control Compartment (ERQC); SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Deactivation of the beta-catenin transactivating complex; Circadian Clock; Regulation of signaling by CBL; Metalloprotease DUBs; Regulation of necroptotic cell death; Oncogene Induced Senescence; Cyclin D associated events in G1; APC/C:Cdc20 mediated degradation of Cyclin B; APC-Cdc20 mediated degradation of Nek2A; Senescence-Associated Secretory Phenotype (SASP); Negative regulation of FLT3; Downregulation of ERBB2:ERBB3 signaling; Interferon alpha/beta signaling; Inactivation of CSF3 (G-CSF) signaling; JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1; Regulation of TP53 Activity through Methylation; Regulation of BACH1 activity; NOD1/2 Signaling Pathway; TICAM1, RIP1-mediated IKK complex recruitment; p75NTR recruits signalling complexes; NF-kB is activated and signals survival; TAK1-dependent IKK and NF-kappa-B activation  ; Regulation of TNFR1 signaling; TNFR1-induced NF-kappa-B signaling pathway; MAP3K8 (TPL2)-dependent MAPK1/3 activation; IRAK1 recruits IKK complex; IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation; Regulation of NF-kappa B signaling; Negative regulators of DDX58/IFIH1 signaling; Prevention of phagosomal-lysosomal fusion; Downregulation of TGF-beta receptor signaling; Downregulation of SMAD2/3:SMAD4 transcriptional activity; Signaling by CSF1 (M-CSF) in myeloid cells; NOTCH1 Intracellular Domain Regulates Transcription; TICAM1-dependent activation of IRF3/IRF7; TICAM1,TRAF6-dependent induction of TAK1 complex; Glycogen synthesis; Formation of TC-NER Pre-Incision Complex; Modulation by Mtb of host immune system; activated TAK1 mediates p38 MAPK activation; IRAK2 mediated activation of TAK1 complex; SARS-CoV-1 activates/modulates innate immune responses; Alpha-protein kinase 1 signaling pathway; Ovarian tumor domain proteases; Spry regulation of FGF signaling; RAS processing; PINK1-PRKN Mediated Mitophagy; Josephin domain DUBs; Regulation of FZD by ubiquitination; Chaperone Mediated Autophagy; Formation of Incision Complex in GG-NER; Iron uptake and transport; VLDLR internalisation and degradation; Myoclonic epilepsy of Lafora; DNA Damage Recognition in GG-NER; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; Negative regulation of MAPK pathway; TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition); NRIF signals cell death from the nucleus; Assembly Of The HIV Virion; Downregulation of ERBB4 signaling; Regulation of innate immune responses to cytosolic DNA; N-glycan trimming in the ER and Calnexin/Calreticulin cycle; PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1; Regulation of PTEN localization; Pexophagy; Maturation of protein E; Maturation of protein E; FLT3 signaling by CBL mutants; TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling"	"Cytoplasmic ribosomal proteins"	"201"	"0"	"2840.6"	"1215.7"	"2361.9"	"2091.9"	"2222.7"	"2634.7"	"2215.1"	"2852.0"	"2487.6"	"4349.2"	"6949.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q10570"	"Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2"	"0.000"	""	"8"	"10"	"18"	"10"	"1443"	"160.8"	"6.40"	"3414.37"	"28.40"	"10"	"8"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03178, Pf10433"	"29894"	"ENSG00000071894; ENSG00000285049"	"CPSF1"	"hsa:29894; Q10570; Q96AF0"	"Transport of Mature mRNA Derived from an Intronless Transcript; tRNA processing in the nucleus; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"mRNA processing"	"7"	"0"	"661.8"	"365.0"	"696.5"	"634.6"	"664.8"	"750.7"	"616.0"	"724.3"	"598.0"	"1031.7"	"1607.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86VM9"	"Zinc finger CCCH domain-containing protein 18 OS=Homo sapiens OX=9606 GN=ZC3H18 PE=1 SV=2"	"0.000"	""	"13"	"13"	"20"	"13"	"953"	"106.3"	"8.32"	"3608.62"	"28.35"	"11"	"9"	"other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf18044"	"124245"	"ENSG00000158545"	"ZC3H18"	"hsa:124245; Q86VM9; Q96DG4; Q96MP7"	""	""	"0"	"0"	"2787.8"	"1286.9"	"2462.3"	"2250.8"	"2292.8"	"2639.8"	"1793.5"	"2519.9"	"1885.7"	"3983.2"	"5340.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12996"	"Cleavage stimulation factor subunit 3 OS=Homo sapiens OX=9606 GN=CSTF3 PE=1 SV=1"	"0.000"	""	"14"	"9"	"22"	"9"	"717"	"82.9"	"8.12"	"4408.08"	"28.32"	"8"	"9"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf05843"	"1479"	"ENSG00000176102"	"CSTF3"	"A8K471; D3DR04; E9PB40; hsa:1479; Q12996; Q32P22; Q96FQ8; Q96QD6; Q96QK4"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"mRNA processing"	"5"	"0"	"824.5"	"333.5"	"707.0"	"559.7"	"659.8"	"720.6"	"538.2"	"756.7"	"527.7"	"1118.4"	"1940.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22061"	"Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4"	"0.000"	""	"35"	"7"	"19"	"7"	"227"	"24.6"	"7.21"	"3844.61"	"28.31"	"7"	"6"	"protein metabolism;other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf01135"	"5110"	"ENSG00000120265"	"PCMT1"	"A8K109; hsa:5110; J3KP72; P22061; Q14661; Q16556; Q5VYC1; Q5VYC2; Q93061; Q96II9; Q99625; Q9BQV7; Q9BQV8; Q9NP03"	"Protein repair"	"Primary ovarian insufficiency"	"2"	"0"	"1429.5"	"739.0"	"1591.1"	"1459.9"	"1540.1"	"1970.7"	"1387.6"	"1682.9"	"1238.1"	"1942.0"	"3176.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99623"	"Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2"	"0.000"	""	"21"	"6"	"17"	"6"	"299"	"33.3"	"9.83"	"3406.25"	"28.26"	"6"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01145"	"11331"	"ENSG00000215021"	"PHB2"	"B4DP75; hsa:11331; Q2YDA4; Q7KYU3; Q92978; Q99623"	"Processing of SMDT1"	""	"1"	"0"	"1161.6"	"381.6"	"761.8"	"637.3"	"796.0"	"869.4"	"672.0"	"1012.8"	"877.3"	"1629.3"	"3144.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16576"	"Histone-binding protein RBBP7 OS=Homo sapiens OX=9606 GN=RBBP7 PE=1 SV=1"	"0.000"	""	"16"	"8"	"19"	"2"	"425"	"47.8"	"5.05"	"3496.88"	"28.24"	"7"	"8"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400, Pf12265"	"5931"	"ENSG00000102054"	"RBBP7"	"hsa:5931; Q16576; Q5JP00"	"Neddylation; Potential therapeutics for SARS; HCMV Early Events; Deposition of new CENPA-containing nucleosomes at the centromere; Oxidative Stress Induced Senescence; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6; HDACs deacetylate histones; Activation of anterior HOX genes in hindbrain development during early embryogenesis; RMTs methylate histone arginines; PKMTs methylate histone lysines; HATs acetylate histones; RNA Polymerase I Transcription Initiation; PRC2 methylates histones and DNA; Defective pyroptosis; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of TP53 Activity through Acetylation"	"Retinoblastoma gene in cancer; Interactome of polycomb repressive complex 2 (PRC2) ; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"20"	"0"	"288.4"	"158.4"	"298.5"	"284.6"	"281.3"	"391.4"	"308.6"	"355.9"	"267.9"	"394.4"	"541.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95819"	"Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens OX=9606 GN=MAP4K4 PE=1 SV=2"	"0.000"	""	"9"	"8"	"13"	"5"	"1239"	"142.0"	"7.46"	"1474.26"	"28.23"	"5"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other cell component"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00069, Pf00780"	"9448"	"ENSG00000071054"	"MAP4K4"	"E7ESS2; hsa:9448; O75172; O95819; Q9NST7"	"Oxidative Stress Induced Senescence"	"MAPK signaling pathway; Angiopoietin-like protein 8 regulatory pathway; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-YAP signaling; Insulin signaling; Pleural mesothelioma"	"7"	"3"	"277.6"	"117.3"	"264.2"	"236.3"	"271.5"	"322.2"	"281.6"	"522.1"	"772.0"	"2821.4"	"2372.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86VN1"	"Vacuolar protein-sorting-associated protein 36 OS=Homo sapiens OX=9606 GN=VPS36 PE=1 SV=1"	"0.000"	""	"25"	"8"	"14"	"8"	"386"	"43.8"	"7.20"	"2365.46"	"28.21"	"6"	"8"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport"	"other membranes;cytosol;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf04157, Pf11605"	"51028"	"ENSG00000136100"	"VPS36"	"A8K125; hsa:51028; Q3ZCV7; Q5H9S1; Q5VXB6; Q86VN1; Q9H8Z5; Q9Y3E3"	"Endosomal Sorting Complex Required For Transport (ESCRT); HCMV Late Events"	"Network map of SARS-CoV-2 signaling pathway"	"3"	"0"	"161.6"	"71.4"	"150.1"	"139.2"	"165.6"	"172.2"	"146.5"	"307.9"	"353.7"	"1588.4"	"3331.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13573"	"SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1"	"0.000"	""	"19"	"9"	"15"	"9"	"536"	"61.5"	"9.52"	"2536.66"	"28.03"	"7"	"8"	"RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus"	"signal transduction activity or receptor binding;other molecular function"	"Pf02731"	"22938"	"ENSG00000100603"	"SNW1"	"A8K8A9; hsa:22938; Q13483; Q13573; Q32N03; Q5D0D6"	"mRNA Splicing - Major Pathway; Formation of paraxial mesoderm; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Pre-NOTCH Transcription and Translation; Downregulation of SMAD2/3:SMAD4 transcriptional activity; NOTCH1 Intracellular Domain Regulates Transcription; Notch-HLH transcription pathway; NOTCH3 Intracellular Domain Regulates Transcription; Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells; NOTCH4 Intracellular Domain Regulates Transcription; RUNX3 regulates NOTCH signaling"	"Novel intracellular components of RIG-I-like receptor pathway; Splicing factor NOVA regulated synaptic proteins; Notch signaling pathway"	"15"	"0"	"1977.0"	"712.6"	"1279.4"	"1132.5"	"1380.2"	"1489.5"	"1082.8"	"1444.0"	"1034.8"	"2024.8"	"3535.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13185"	"Chromobox protein homolog 3 OS=Homo sapiens OX=9606 GN=CBX3 PE=1 SV=4"	"0.000"	""	"42"	"6"	"16"	"4"	"183"	"20.8"	"5.33"	"4414.22"	"28.03"	"6"	"5"	"cell organization and biogenesis;stress response;other biological processes"	"other membranes;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00385, Pf01393"	"11335"	"ENSG00000122565"	"CBX3"	"hsa:11335; Q13185; Q96CD7; Q99409; Q9BVS3; Q9P0Z6"	"RNA Polymerase I Promoter Escape; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Transcriptional Regulation by E2F6"	"Exercise-induced circadian regulation; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; NIPBL role in DNA damage - Cornelia de Lange syndrome"	"6"	"4"	"868.0"	"351.4"	"801.7"	"790.4"	"856.7"	"1085.0"	"965.8"	"1374.8"	"918.5"	"1281.0"	"2045.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2Z4"	"Tyrosine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=YARS2 PE=1 SV=2"	"0.000"	""	"20"	"7"	"13"	"7"	"477"	"53.2"	"8.98"	"2449.13"	"27.94"	"6"	"7"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00579"	"51067"	"ENSG00000139131"	"YARS2"	"D3DUW8; hsa:51067; Q9H817; Q9Y2Z4"	"Mitochondrial tRNA aminoacylation"	"Orexin receptor pathway"	"2"	"0"	"397.7"	"160.7"	"381.0"	"259.0"	"295.3"	"358.8"	"265.2"	"372.3"	"404.2"	"1156.2"	"2438.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14126"	"Desmoglein-2 OS=Homo sapiens OX=9606 GN=DSG2 PE=1 SV=2"	"0.000"	""	"9"	"7"	"13"	"7"	"1118"	"122.2"	"5.24"	"2060.45"	"27.81"	"6"	"7"	"cell adhesion;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00028"	"1829"	"ENSG00000046604"	"DSG2"	"hsa:1829; Q14126; Q4KKU6"	"Formation of the cornified envelope; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; Apoptotic cleavage of cell adhesion  proteins"	"Arrhythmogenic right ventricular cardiomyopathy; GDNF signaling"	"8"	"0"	"787.9"	"262.3"	"578.7"	"480.9"	"589.7"	"618.8"	"480.2"	"602.3"	"505.9"	"1035.2"	"2108.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NCB2"	"CaM kinase-like vesicle-associated protein OS=Homo sapiens OX=9606 GN=CAMKV PE=2 SV=2"	"0.000"	""	"15"	"7"	"15"	"7"	"501"	"54.3"	"5.55"	"2472.32"	"27.80"	"6"	"7"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"79012"	"ENSG00000164076"	"CAMKV"	"A6NFD4; hsa:79012; Q6FIB8; Q8NBS8; Q8NC85; Q8NCB2; Q8NDU4; Q8WTT8; Q9BQC9; Q9H0Q5"	""	""	"0"	"0"	"255.8"	"114.2"	"211.6"	"187.4"	"216.2"	"233.8"	"191.2"	"409.6"	"833.0"	"2567.4"	"2012.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43172"	"U4/U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2"	"0.000"	""	"18"	"7"	"13"	"7"	"522"	"58.4"	"7.42"	"2406.01"	"27.70"	"6"	"7"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00400, Pf08799"	"9128"	"ENSG00000136875"	"PRPF4"	"hsa:9128; O43172; O43445; O43864; Q5T1M8; Q96DG2; Q96IK4"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"0"	"775.7"	"271.6"	"601.5"	"542.2"	"563.4"	"674.1"	"478.2"	"685.8"	"462.6"	"986.1"	"1914.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WWY3"	"U4/U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2"	"0.000"	""	"15"	"6"	"12"	"6"	"499"	"55.4"	"5.78"	"2189.99"	"27.65"	"4"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01798, Pf09785"	"26121"	"ENSG00000105618; ENSG00000274144; ENSG00000274651; ENSG00000274894; ENSG00000275117; ENSG00000275885; ENSG00000276421; ENSG00000277154; ENSG00000277707; ENSG00000277953"	"PRPF31"	"E7ESA8; F1T0A4; F1T0A5; hsa:26121; Q17RB4; Q8N7F9; Q8WWY3; Q9H271; Q9Y439"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"1251.6"	"412.4"	"920.6"	"782.3"	"964.7"	"1080.7"	"762.1"	"1068.2"	"719.5"	"1683.6"	"3174.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25098"	"Beta-adrenergic receptor kinase 1 OS=Homo sapiens OX=9606 GN=GRK2 PE=1 SV=2"	"0.000"	""	"14"	"8"	"12"	"8"	"689"	"79.5"	"7.28"	"1549.45"	"27.64"	"5"	"7"	"cell-cell signaling;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf00069, Pf00169, Pf00615"	"156"	"ENSG00000173020"	"GRK2"	"B0ZBE1; hsa:156; P25098; Q13837; Q6GTT3"	"G alpha (q) signalling events; Activation of SMO; G alpha (s) signalling events; Cargo recognition for clathrin-mediated endocytosis; Calmodulin induced events"	"Chemokine signaling pathway; Hedgehog signaling pathway; Hedgehog signaling pathway"	"8"	"0"	"253.6"	"105.4"	"221.1"	"180.8"	"225.3"	"259.4"	"204.1"	"329.9"	"374.0"	"1854.4"	"4557.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13576"	"Ras GTPase-activating-like protein IQGAP2 OS=Homo sapiens OX=9606 GN=IQGAP2 PE=1 SV=4"	"0.000"	""	"6"	"8"	"11"	"7"	"1575"	"180.5"	"5.64"	"897.21"	"27.61"	"3"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00307, Pf00612, Pf00616, Pf03836"	"10788"	"ENSG00000145703"	"IQGAP2"	"A8K4V1; B7Z8A4; hsa:10788; J3KR91; Q13576"	"Neutrophil degranulation; RHO GTPases activate IQGAPs; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOG GTPase cycle"	"Ciliary landscape; G13 signaling pathway"	"7"	"0"	"229.9"	"107.6"	"188.8"	"167.7"	"190.2"	"220.9"	"176.3"	"253.7"	"288.3"	"1026.8"	"2289.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BT78"	"COP9 signalosome complex subunit 4 OS=Homo sapiens OX=9606 GN=COPS4 PE=1 SV=1"	"0.000"	""	"23"	"7"	"13"	"7"	"406"	"46.2"	"5.83"	"2373.31"	"27.58"	"6"	"7"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf01399, Pf18420"	"51138"	"ENSG00000138663"	"COPS4"	"B3KN88; B3KST5; hsa:51138; Q561W7; Q9BT78; Q9NW31; Q9Y677"	"Cargo recognition for clathrin-mediated endocytosis; Neddylation; Formation of TC-NER Pre-Incision Complex; DNA Damage Recognition in GG-NER; RHOBTB1 GTPase cycle"	"Ciliary landscape"	"6"	"0"	"253.8"	"114.9"	"223.7"	"235.2"	"248.0"	"302.1"	"284.8"	"478.5"	"455.8"	"846.4"	"2446.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P39023"	"60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2"	"0.000"	""	"18"	"7"	"18"	"7"	"403"	"46.1"	"10.18"	"2670.47"	"27.53"	"6"	"7"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00297"	"6122"	"ENSG00000100316"	"RPL3"	"B2RDV9; hsa:6122; P39023; Q15548; Q5I0G0"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"2527.9"	"944.1"	"2115.0"	"1830.3"	"2061.0"	"2435.8"	"1678.7"	"2274.6"	"1590.0"	"3134.2"	"5056.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EP5"	"DAZ-associated protein 1 OS=Homo sapiens OX=9606 GN=DAZAP1 PE=1 SV=1"	"0.000"	""	"17"	"6"	"16"	"6"	"407"	"43.4"	"8.56"	"3654.78"	"27.50"	"5"	"5"	"cell cycle OR cell proliferation;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"26528"	"ENSG00000071626"	"DAZAP1"	"hsa:26528; Q96EP5; Q96MJ3; Q9NRR9"	""	""	"0"	"0"	"664.3"	"343.7"	"719.5"	"620.7"	"608.4"	"782.1"	"555.9"	"755.6"	"607.7"	"1006.3"	"1380.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKM9"	"RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1"	"0.000"	""	"26"	"7"	"14"	"7"	"306"	"32.4"	"9.17"	"2689.92"	"27.43"	"6"	"6"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00076"	"22913"	"ENSG00000125970"	"RALY"	"hsa:22913; Q14621; Q2M365; Q5QPL8; Q9BQX6; Q9UJE3; Q9UKM9"	""	""	"0"	"0"	"1034.2"	"258.2"	"616.1"	"536.9"	"631.3"	"729.1"	"583.8"	"789.3"	"633.2"	"1172.5"	"2162.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6PI48"	"Aspartate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=DARS2 PE=1 SV=1"	"0.000"	""	"17"	"9"	"17"	"9"	"645"	"73.5"	"8.02"	"3075.44"	"27.42"	"8"	"8"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00152, Pf01336, Pf02938"	"55157"	"ENSG00000117593"	"DARS2"	"hsa:55157; Q6PI48"	"Mitochondrial tRNA aminoacylation"	""	"1"	"0"	"835.3"	"381.9"	"855.7"	"719.7"	"791.7"	"946.4"	"687.5"	"850.5"	"639.3"	"1463.7"	"3841.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05388"	"60S acidic ribosomal protein P0 OS=Homo sapiens OX=9606 GN=RPLP0 PE=1 SV=1"	"0.000"	""	"27"	"8"	"16"	"8"	"317"	"34.3"	"5.97"	"2982.00"	"27.32"	"8"	"8"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00428, Pf00466, Pf17777"	"6175"	"ENSG00000089157"	"RPLP0"	"hsa:6175; P05388; Q3B7A4; Q9BVK4"	"Regulation of expression of SLITs and ROBOs; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"15"	"0"	"1110.5"	"419.7"	"909.0"	"771.6"	"890.1"	"1124.6"	"786.4"	"975.7"	"727.6"	"1338.3"	"2154.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50502"	"Hsc70-interacting protein OS=Homo sapiens OX=9606 GN=ST13 PE=1 SV=2"	"0.000"	""	"18"	"8"	"19"	"8"	"369"	"41.3"	"5.27"	"3250.70"	"27.27"	"8"	"8"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf17830, Pf18253"	"6767"	"ENSG00000100380"	"ST13"	"hsa:6767; O14999; P50502; Q2TU77"	"Regulation of HSF1-mediated heat shock response"	""	"1"	"0"	"954.1"	"472.5"	"925.6"	"801.5"	"1027.9"	"1121.8"	"901.0"	"1079.7"	"982.6"	"1595.5"	"2776.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07197"	"Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3"	"0.000"	""	"11"	"10"	"20"	"7"	"916"	"102.4"	"4.91"	"3271.19"	"27.15"	"9"	"9"	"cell organization and biogenesis"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00038, Pf04732"	"4741"	"ENSG00000104722"	"NEFM"	"B4DGN2; E9PBF7; hsa:4741; P07197; Q4QRK6"	""	"Amyotrophic lateral sclerosis (ALS); Physico-chemical features and toxicity-associated pathways; Ciliary landscape"	"3"	"2"	"1974.1"	"700.4"	"1328.5"	"1062.5"	"1394.8"	"1433.9"	"1025.7"	"1449.6"	"1221.4"	"2220.1"	"4247.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P48735"	"Isocitrate dehydrogenase [NADP], mitochondrial OS=Homo sapiens OX=9606 GN=IDH2 PE=1 SV=2"	"0.000"	""	"17"	"7"	"15"	"7"	"452"	"50.9"	"8.69"	"3195.32"	"27.14"	"7"	"6"	"other metabolic processes"	"cytosol;mitochondrion;other cytoplasmic organelle"	"other molecular function"	"Pf00180"	"3418"	"ENSG00000182054"	"IDH2"	"B2R6L6; B4DFL2; hsa:3418; P48735; Q96GT3"	"Transcriptional activation of mitochondrial biogenesis; Citric acid cycle (TCA cycle)"	"VEGFA-VEGFR2 signaling; Metabolic reprogramming in colon cancer; Cerebral organic acidurias, including diseases; TCA cycle (aka Krebs or citric acid cycle)"	"6"	"0"	"664.2"	"354.7"	"654.4"	"582.0"	"628.7"	"782.7"	"522.4"	"721.5"	"486.8"	"892.5"	"1758.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P12268"	"Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2"	"0.000"	""	"18"	"8"	"15"	"8"	"514"	"55.8"	"6.90"	"3724.81"	"27.01"	"7"	"7"	"cell cycle OR cell proliferation;other metabolic processes;developmental processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00478, Pf00571"	"3615"	"ENSG00000178035"	"IMPDH2"	"hsa:3615; P12268; Q6LEF3"	"Neutrophil degranulation; Potential therapeutics for SARS; Purine ribonucleoside monophosphate biosynthesis; Azathioprine ADME"	"Rett syndrome causing genes"	"5"	"0"	"1332.8"	"491.8"	"1219.2"	"977.1"	"970.4"	"1328.7"	"851.4"	"1018.5"	"887.6"	"1712.4"	"3499.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46782"	"40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4"	"0.000"	""	"37"	"7"	"15"	"7"	"204"	"22.9"	"9.72"	"2592.44"	"27.01"	"6"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00177"	"6193"	"ENSG00000083845"	"RPS5"	"B2R4T2; hsa:6193; P46782; Q96BN0"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"1096.2"	"536.4"	"954.7"	"843.6"	"932.7"	"1161.0"	"914.7"	"1081.9"	"854.6"	"1376.3"	"2140.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23528"	"Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3"	"0.000"	""	"57"	"8"	"14"	"7"	"166"	"18.5"	"8.09"	"2800.36"	"26.83"	"7"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf00241"	"1072"	"ENSG00000172757"	"CFL1"	"B3KUQ1; hsa:1072; P23528; Q53Y87; Q9UCA2"	"Platelet degranulation ; Regulation of actin dynamics for phagocytic cup formation; EPHB-mediated forward signaling; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Sema3A PAK dependent Axon repulsion; RHO GTPases Activate ROCKs"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; VEGFA-VEGFR2 signaling; EGF/EGFR signaling pathway; Envelope proteins and their potential roles in EDMD physiopathology; 7q11.23 copy number variation syndrome; Neuroinflammation and glutamatergic signaling; CCL18 signaling pathway; Regulation of actin cytoskeleton; G13 signaling pathway"	"15"	"1"	"1605.1"	"448.4"	"1058.6"	"741.1"	"1140.0"	"1159.4"	"890.8"	"1198.6"	"1015.5"	"1773.9"	"3698.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05387"	"60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1"	"0.000"	""	"60"	"4"	"11"	"4"	"115"	"11.7"	"4.54"	"2165.61"	"26.73"	"3"	"4"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf00428"	"6181"	"ENSG00000177600"	"RPLP2"	"hsa:6181; P05387; Q6FG96"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins; Opioid receptor pathways"	"16"	"0"	"882.7"	"285.5"	"584.7"	"455.8"	"685.5"	"757.8"	"546.4"	"739.9"	"579.7"	"941.9"	"1703.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50995"	"Annexin A11 OS=Homo sapiens OX=9606 GN=ANXA11 PE=1 SV=1"	"0.000"	""	"21"	"9"	"16"	"9"	"505"	"54.4"	"7.65"	"2634.84"	"26.68"	"8"	"8"	"cell cycle OR cell proliferation;transport;other biological processes"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00191"	"311"	"ENSG00000122359"	"ANXA11"	"B4DVE7; hsa:311; P50995"	""	""	"0"	"0"	"1081.1"	"452.5"	"958.6"	"829.1"	"1055.0"	"1113.5"	"824.0"	"1062.5"	"878.8"	"1622.1"	"2591.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25787"	"Proteasome subunit alpha type-2 OS=Homo sapiens OX=9606 GN=PSMA2 PE=1 SV=2"	"0.000"	""	"22"	"4"	"14"	"4"	"234"	"25.9"	"7.43"	"2736.01"	"26.57"	"4"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf00227, Pf10584"	"5683"	"ENSG00000106588"	"PSMA2"	"hsa:5683; P25787; Q6ICS6; Q9BU45"	"ER-Phagosome pathway; Neutrophil degranulation; Ub-specific processing proteases; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"63"	"0"	"657.5"	"281.1"	"586.1"	"522.4"	"564.4"	"640.0"	"553.6"	"755.3"	"589.8"	"803.2"	"1413.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02878"	"60S ribosomal protein L6 OS=Homo sapiens OX=9606 GN=RPL6 PE=1 SV=3"	"0.000"	""	"26"	"8"	"19"	"8"	"288"	"32.7"	"10.58"	"3470.42"	"26.55"	"8"	"8"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01159, Pf03868"	"6128"	"ENSG00000089009"	"RPL6"	"hsa:6128; Q02878; Q2M3Q3; Q8WW97"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"1711.6"	"688.2"	"1439.7"	"1212.7"	"1309.7"	"1577.6"	"1164.1"	"1521.6"	"1225.2"	"2056.9"	"2978.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49736"	"DNA replication licensing factor MCM2 OS=Homo sapiens OX=9606 GN=MCM2 PE=1 SV=4"	"0.000"	""	"7"	"7"	"17"	"7"	"904"	"101.8"	"5.52"	"3463.41"	"26.52"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf12619, Pf14551, Pf17207, Pf17855"	"4171"	"ENSG00000073111"	"MCM2"	"hsa:4171; P49736; Q14577; Q15023; Q8N2V1; Q969W7; Q96AE1; Q9BRM7"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"Cell cycle; Ciliary landscape; G1 to S cell cycle control; DNA replication; 1p36 copy number variation syndrome"	"11"	"0"	"845.5"	"313.6"	"681.9"	"530.5"	"653.2"	"800.9"	"729.5"	"939.0"	"769.6"	"1016.2"	"1813.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13647"	"Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3"	"0.000"	""	"11"	"8"	"16"	"3"	"590"	"62.3"	"7.74"	"2342.90"	"26.48"	"7"	"8"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;other cell component"	"bone, tooth or skin structural activity;cytoskeletal activity;other molecular function"	"Pf00038, Pf16208"	"3852"	"ENSG00000186081"	"KRT5"	"hsa:3852; P13647; Q6PI71; Q6UBJ0; Q8TA91"	"Formation of the cornified envelope; Type I hemidesmosome assembly"	""	"3"	"0"	"84.5"	"466.8"	"88.1"	"26.0"	"298.8"	"80.7"	"67.6"	"83.1"	"320.3"	"142.8"	"484.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01085"	"Nucleolysin TIAR OS=Homo sapiens OX=9606 GN=TIAL1 PE=1 SV=1"	"0.000"	""	"18"	"6"	"18"	"4"	"375"	"41.6"	"7.74"	"2780.54"	"26.46"	"6"	"6"	"cell cycle OR cell proliferation;stress response;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"7073"	"ENSG00000151923"	"TIAL1"	"A8K3T0; A8K4L9; hsa:7073; Q01085"	"FGFR2 alternative splicing"	""	"1"	"2"	"1128.5"	"462.6"	"1105.8"	"915.1"	"1013.7"	"1210.9"	"841.1"	"1130.9"	"890.5"	"1881.9"	"2964.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P06733"	"Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2"	"0.000"	""	"21"	"7"	"15"	"7"	"434"	"47.1"	"7.39"	"2072.83"	"26.39"	"6"	"7"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00113, Pf03952"	"2023"	"ENSG00000074800"	"ENO1"	"B2RD59; hsa:2023; P06733; P22712; Q16704; Q4TUS4; Q53FT9; Q53HR3; Q658M5; Q6GMP2; Q71V37; Q7Z3V6; Q8WU71; Q96GV1; Q9BT62; Q9UCH6; Q9UM55"	"Glycolysis; Gluconeogenesis; Manipulation of host energy metabolism"	"Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; IL-18 signaling pathway; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"9"	"0"	"1398.6"	"371.2"	"832.4"	"496.1"	"866.8"	"720.7"	"793.0"	"900.2"	"971.9"	"1542.7"	"3580.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P98179"	"RNA-binding protein 3 OS=Homo sapiens OX=9606 GN=RBM3 PE=1 SV=1"	"0.000"	""	"33"	"4"	"15"	"4"	"157"	"17.2"	"8.91"	"2091.13"	"26.38"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"translation activity"	"Pf00076"	"5935"	"ENSG00000102317"	"RBM3"	"hsa:5935; P98179"	""	""	"0"	"0"	"898.7"	"405.9"	"648.0"	"592.1"	"559.9"	"670.6"	"574.9"	"716.2"	"574.6"	"791.3"	"1050.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13868"	"Exosome complex component RRP4 OS=Homo sapiens OX=9606 GN=EXOSC2 PE=1 SV=2"	"0.000"	""	"18"	"4"	"14"	"4"	"293"	"32.8"	"7.50"	"3078.64"	"26.37"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf14382, Pf15985"	"23404"	"ENSG00000130713"	"EXOSC2"	"A3KFL3; A3KFL4; B4DKK6; hsa:23404; Q13868; Q9NUY4"	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	"Ciliary landscape"	"7"	"0"	"529.8"	"222.5"	"416.6"	"373.1"	"466.3"	"537.4"	"462.3"	"635.9"	"549.2"	"1024.1"	"1624.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61964"	"WD repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=WDR5 PE=1 SV=1"	"0.000"	""	"22"	"6"	"14"	"6"	"334"	"36.6"	"8.27"	"2432.19"	"26.27"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00400"	"11091"	"ENSG00000196363"	"WDR5"	"hsa:11091; P61964; Q91VA5; Q9NWX7; Q9UGP9"	"Neddylation; Formation of WDR5-containing histone-modifying complexes; Activation of anterior HOX genes in hindbrain development during early embryogenesis; RMTs methylate histone arginines; PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; HATs acetylate histones; Cardiogenesis"	"Pleural mesothelioma; Kleefstra syndrome"	"10"	"0"	"648.2"	"302.2"	"782.9"	"802.8"	"737.5"	"947.2"	"668.4"	"822.2"	"537.4"	"1188.3"	"1380.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14566"	"DNA replication licensing factor MCM6 OS=Homo sapiens OX=9606 GN=MCM6 PE=1 SV=1"	"0.000"	""	"12"	"8"	"12"	"8"	"821"	"92.8"	"5.41"	"1922.89"	"26.27"	"5"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855, Pf18263"	"4175"	"ENSG00000076003"	"MCM6"	"B2R6H2; hsa:4175; Q13504; Q14566; Q99859"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"Cell cycle; Retinoblastoma gene in cancer; Ciliary landscape; G1 to S cell cycle control; DNA replication"	"11"	"0"	"735.9"	"257.2"	"557.2"	"477.0"	"591.5"	"707.9"	"630.7"	"900.0"	"673.1"	"858.5"	"1552.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63220"	"40S ribosomal protein S21 OS=Homo sapiens OX=9606 GN=RPS21 PE=1 SV=1"	"0.000"	""	"48"	"4"	"16"	"4"	"83"	"9.1"	"8.50"	"3081.65"	"26.24"	"4"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01249"	"6227"	"ENSG00000171858"	"RPS21"	"hsa:6227; P35265; P63220"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"1526.8"	"712.0"	"1410.9"	"1281.0"	"1285.8"	"1601.9"	"1187.6"	"1608.9"	"1158.8"	"2013.8"	"2820.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95831"	"Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1"	"0.000"	""	"14"	"7"	"13"	"7"	"613"	"66.9"	"8.95"	"2552.14"	"26.22"	"6"	"7"	"cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00070, Pf14721"	"9131"	"ENSG00000156709"	"AIFM1"	"A4QPB4; B1ALN1; B2RB08; D3DTE9; E9PRR0; hsa:9131; O95831; Q1L6K4; Q1L6K6; Q2QKE4; Q5JUZ7; Q6I9X6; Q9Y3I3; Q9Y3I4"	""	"Apoptosis modulation and signaling; Nanomaterial induced apoptosis; Apoptosis modulation by HSP70"	"3"	"0"	"881.4"	"390.4"	"769.8"	"692.1"	"808.4"	"953.5"	"699.0"	"827.8"	"748.5"	"1071.8"	"1717.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46783"	"40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1"	"0.000"	""	"42"	"7"	"25"	"6"	"165"	"18.9"	"10.15"	"4921.48"	"26.17"	"7"	"5"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf03501"	"6204"	"ENSG00000124614"	"RPS10"	"B2R4E3; hsa:6204; P46783; Q5TZC0"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"2357.3"	"1140.0"	"2235.6"	"2013.1"	"2097.7"	"2655.6"	"1956.9"	"2469.7"	"1809.3"	"3034.5"	"3264.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15446"	"DNA-directed RNA polymerase I subunit RPA34 OS=Homo sapiens OX=9606 GN=CD3EAP PE=1 SV=1"	"0.000"	""	"20"	"6"	"11"	"6"	"510"	"55.0"	"8.51"	"2187.10"	"26.14"	"5"	"6"	"RNA metabolism OR transcription;other metabolic processes;signal transduction"	"cytosol;mitochondrion;nucleus;other cell component"	""	"Pf08208"	"10849"	"ENSG00000117877"	"POLR1G"	"hsa:10849; O15446; Q32N11; Q7Z5U2; Q9UPF6"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"2q13 copy number variation syndrome"	"6"	"0"	"132.2"	"55.0"	"124.5"	"103.6"	"123.3"	"135.3"	"110.8"	"265.7"	"530.7"	"1444.3"	"2342.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62851"	"40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1"	"0.000"	""	"33"	"5"	"18"	"5"	"125"	"13.7"	"10.11"	"3181.66"	"26.08"	"5"	"5"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf03297"	"6230"	"ENSG00000118181; ENSG00000280831"	"RPS25"	"B2R4M7; hsa:6230; P25111; P62851"	"Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Peptide chain elongation; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"1998.6"	"868.5"	"1851.7"	"1620.5"	"1623.4"	"2089.5"	"1439.4"	"1974.6"	"1200.1"	"2158.6"	"3311.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62937"	"Peptidyl-prolyl cis-trans isomerase A OS=Homo sapiens OX=9606 GN=PPIA PE=1 SV=2"	"0.000"	""	"36"	"7"	"17"	"7"	"165"	"18.0"	"7.81"	"2990.24"	"26.07"	"7"	"6"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00160"	"5478"	"ENSG00000196262"	"PPIA"	"A8K220; hsa:5478; P05092; P62937; Q3KQW3; Q567Q0; Q6IBU5; Q96IX3; Q9BRU4; Q9BTY9; Q9UC61"	"Neutrophil degranulation; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Budding and maturation of HIV virion; Platelet degranulation ; Basigin interactions; SARS-CoV-1 activates/modulates innate immune responses; Integration of provirus; APOBEC3G mediated resistance to HIV-1 infection; Calcineurin activates NFAT; Binding and entry of HIV virion; Assembly Of The HIV Virion; Uncoating of the HIV Virion; Minus-strand DNA synthesis; Plus-strand DNA synthesis"	"Prolactin signaling pathway"	"16"	"0"	"1487.7"	"494.2"	"942.9"	"650.9"	"998.2"	"900.5"	"934.0"	"1027.3"	"1252.6"	"1707.1"	"3465.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UQ13"	"Leucine-rich repeat protein SHOC-2 OS=Homo sapiens OX=9606 GN=SHOC2 PE=1 SV=2"	"0.000"	""	"16"	"7"	"12"	"7"	"582"	"64.8"	"8.46"	"1684.64"	"26.05"	"5"	"7"	"signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf13855"	"8036"	"ENSG00000108061"	"SHOC2"	"A8K9W8; B3KR23; hsa:8036; O76063; Q5VZS8; Q5VZS9; Q9UQ13"	"RAF activation; SHOC2 M1731 mutant abolishes MRAS complex function; Gain-of-function MRAS complexes activate RAF signaling"	"Ras signaling; 22q11.2 copy number variation syndrome; Autophagy in pancreatic ductal adenocarcinoma"	"6"	"0"	"350.0"	"125.9"	"298.4"	"253.1"	"305.4"	"338.6"	"227.8"	"327.8"	"286.7"	"2302.4"	"4030.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75689"	"Arf-GAP with dual PH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ADAP1 PE=1 SV=2"	"0.000"	""	"25"	"8"	"15"	"8"	"374"	"43.4"	"8.97"	"3153.07"	"25.98"	"8"	"6"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf01412"	"11033"	"ENSG00000105963"	"ADAP1"	"A4D2Q2; B3KRZ4; B4DVA6; F6XZ68; H7C2Q4; hsa:11033; O75689"	"Nuclear signaling by ERBB4"	""	"1"	"0"	"250.8"	"155.3"	"230.9"	"224.2"	"244.4"	"305.8"	"369.8"	"875.1"	"1802.6"	"4227.8"	"4475.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q00535"	"Cyclin-dependent-like kinase 5 OS=Homo sapiens OX=9606 GN=CDK5 PE=1 SV=3"	"0.000"	""	"33"	"8"	"16"	"8"	"292"	"33.3"	"7.66"	"2975.39"	"25.95"	"7"	"7"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;kinase activity;other molecular function"	"Pf00069"	"1020"	"ENSG00000164885"	"CDK5"	"A1XKG3; hsa:1020; Q00535"	"DARPP-32 events; NPAS4 regulates expression of target genes; NGF-stimulated transcription; Regulation of TP53 Activity through Phosphorylation; Factors involved in megakaryocyte development and platelet production; CRMPs in Sema3A signaling; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models; Activated NTRK2 signals through CDK5"	"miRNA regulation of DNA damage response; Nicotine effect on dopaminergic neurons; Alzheimer's disease and miRNA effects; Brain-derived neurotrophic factor (BDNF) signaling pathway; ATM signaling in development and disease ; Alzheimer's disease; Neurogenesis regulation in the olfactory epithelium; DNA damage response"	"16"	"0"	"282.8"	"120.0"	"254.4"	"251.2"	"268.5"	"562.5"	"924.8"	"1858.9"	"1847.5"	"4210.0"	"6264.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UEY8"	"Gamma-adducin OS=Homo sapiens OX=9606 GN=ADD3 PE=1 SV=1"	"0.000"	""	"11"	"7"	"11"	"6"	"706"	"79.1"	"6.32"	"1688.48"	"25.92"	"3"	"6"	"cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00596"	"120"	"ENSG00000148700"	"ADD3"	"D3DRA8; hsa:120; O43243; Q5VU09; Q92773; Q9UEY7; Q9UEY8"	"Miscellaneous transport and binding events; RHOD GTPase cycle; RHOF GTPase cycle"	""	"3"	"0"	"274.9"	"128.2"	"241.5"	"227.6"	"233.3"	"293.2"	"243.7"	"411.5"	"319.8"	"1152.3"	"2982.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62841"	"40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2"	"0.000"	""	"37"	"3"	"12"	"3"	"145"	"17.0"	"10.39"	"2120.78"	"25.86"	"2"	"3"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00203"	"6209"	"ENSG00000115268"	"RPS15"	"A5D8V9; hsa:6209; P11174; P62841; Q3KRA1; Q9UDC2"	"Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; SRP-dependent cotranslational protein targeting to membrane; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SARS-CoV-2 modulates host translation machinery; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"679.8"	"287.4"	"596.4"	"486.9"	"554.0"	"691.8"	"530.4"	"724.1"	"525.7"	"836.7"	"1196.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46777"	"60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3"	"0.000"	""	"24"	"7"	"16"	"7"	"297"	"34.3"	"9.72"	"3767.15"	"25.81"	"7"	"6"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf14204, Pf17144"	"6125"	"ENSG00000122406"	"RPL5"	"hsa:6125; P46777; Q32LZ3; Q53HH6; Q9H3F4"	"SRP-dependent cotranslational protein targeting to membrane; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"15"	"0"	"1803.5"	"625.0"	"1617.4"	"1417.9"	"1485.1"	"1781.1"	"1246.0"	"1714.6"	"1172.2"	"2221.8"	"3501.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z6E9"	"E3 ubiquitin-protein ligase RBBP6 OS=Homo sapiens OX=9606 GN=RBBP6 PE=1 SV=1"	"0.000"	""	"4"	"7"	"14"	"7"	"1792"	"201.4"	"9.64"	"2493.34"	"25.61"	"6"	"6"	"protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf04564, Pf08783, Pf13696"	"5930"	"ENSG00000122257"	"RBBP6"	"hsa:5930; Q147T5; Q15290; Q6DKH4; Q6P4C2; Q6YNC9; Q7Z6E8; Q7Z6E9; Q8N0V2; Q96PH3; Q9H3I8; Q9H5M5; Q9NPX4"	"Antigen processing: Ubiquitination & Proteasome degradation; RHOBTB1 GTPase cycle"	""	"2"	"0"	"455.0"	"202.6"	"394.8"	"348.0"	"387.0"	"462.0"	"363.1"	"562.8"	"471.1"	"1306.6"	"2929.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27816"	"Microtubule-associated protein 4 OS=Homo sapiens OX=9606 GN=MAP4 PE=1 SV=3"	"0.000"	""	"10"	"10"	"17"	"10"	"1152"	"120.9"	"5.43"	"4058.83"	"25.52"	"10"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00418"	"4134"	"ENSG00000047849"	"MAP4"	"hsa:4134; P27816; Q13082; Q59FT2; Q68D74; Q6ZUW9; Q86V26; Q96A76; Q96NS9"	""	"Splicing factor NOVA regulated synaptic proteins; 2q37 copy number variation syndrome"	"2"	"0"	"1206.9"	"460.3"	"1085.2"	"963.1"	"1030.9"	"1177.0"	"772.9"	"1146.7"	"752.6"	"1615.7"	"3142.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKV3"	"Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2"	"0.000"	""	"7"	"9"	"15"	"9"	"1341"	"151.8"	"6.43"	"3267.44"	"25.37"	"8"	"7"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02037, Pf16294"	"22985"	"ENSG00000100813"	"ACIN1"	"B2RTT4; D3DS45; hsa:22985; O75158; Q9UG91; Q9UKV1; Q9UKV2; Q9UKV3"	"mRNA Splicing - Major Pathway; Apoptotic cleavage of cellular proteins"	""	"2"	"0"	"2472.6"	"472.3"	"996.6"	"789.1"	"1076.4"	"1082.5"	"1016.6"	"1456.5"	"1141.6"	"2153.8"	"5384.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WVV9"	"Heterogeneous nuclear ribonucleoprotein L-like OS=Homo sapiens OX=9606 GN=HNRNPLL PE=1 SV=1"	"0.000"	""	"14"	"6"	"14"	"5"	"542"	"60.0"	"7.72"	"1892.43"	"25.21"	"5"	"6"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf11835, Pf13893"	"92906"	"ENSG00000143889"	"HNRNPLL"	"hsa:92906; Q53T80; Q5JB51; Q5JB52; Q659B9; Q8IVH5; Q8IVH6; Q8WVV9; Q96HR5"	""	""	"0"	"0"	"187.3"	"51.6"	"171.9"	"176.1"	"167.9"	"224.5"	"148.0"	"229.8"	"135.9"	"219.5"	"348.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P37108"	"Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2"	"0.000"	""	"51"	"8"	"27"	"8"	"136"	"14.6"	"10.04"	"5631.34"	"25.11"	"7"	"5"	"transport"	"non-structural extracellular;cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02290"	"6727"	"ENSG00000140319"	"SRP14"	"B5BUF5; hsa:6727; P37108; Q6B0K5; Q96Q14"	"Neutrophil degranulation; SRP-dependent cotranslational protein targeting to membrane"	""	"2"	"0"	"1146.4"	"461.7"	"1063.0"	"845.0"	"924.3"	"1162.6"	"875.2"	"1232.8"	"2882.9"	"24435.1"	"7283.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62750"	"60S ribosomal protein L23a OS=Homo sapiens OX=9606 GN=RPL23A PE=1 SV=1"	"0.000"	""	"46"	"7"	"18"	"7"	"156"	"17.7"	"10.45"	"3216.88"	"25.05"	"7"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00276, Pf03939"	"6147"	"ENSG00000198242"	"RPL23A"	"B2R5B2; hsa:6147; P29316; P39024; P62750; Q92774"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"2100.8"	"924.2"	"1602.5"	"1314.3"	"1518.3"	"1739.8"	"1299.7"	"1688.2"	"1428.9"	"2173.8"	"2917.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13011"	"Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial OS=Homo sapiens OX=9606 GN=ECH1 PE=1 SV=2"	"0.000"	""	"20"	"7"	"12"	"7"	"328"	"35.8"	"8.00"	"1804.74"	"24.97"	"4"	"6"	"other metabolic processes"	"cytosol;mitochondrion;other cytoplasmic organelle"	"other molecular function"	"Pf00378"	"1891"	"ENSG00000104823; ENSG00000282853"	"ECH1"	"A8K745; hsa:1891; Q13011; Q8WVX0; Q96EZ9"	"Peroxisomal protein import"	"Fatty acid biosynthesis; IL-18 signaling pathway"	"3"	"0"	"546.7"	"265.6"	"528.7"	"536.0"	"562.7"	"645.0"	"478.4"	"691.9"	"639.3"	"2593.3"	"5548.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62314"	"Small nuclear ribonucleoprotein Sm D1 OS=Homo sapiens OX=9606 GN=SNRPD1 PE=1 SV=1"	"0.000"	""	"37"	"3"	"13"	"3"	"119"	"13.3"	"11.56"	"2216.19"	"24.92"	"2"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01423"	"6632"	"ENSG00000167088"	"SNRPD1"	"B5BTZ1; hsa:6632; P13641; P62314"	"mRNA Splicing - Major Pathway; SARS-CoV-2 modulates host translation machinery; snRNP Assembly; mRNA Splicing - Minor Pathway"	"mRNA processing"	"5"	"0"	"317.7"	"130.0"	"232.4"	"184.5"	"276.0"	"262.7"	"242.5"	"314.7"	"270.3"	"433.6"	"640.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BW27"	"Nuclear pore complex protein Nup85 OS=Homo sapiens OX=9606 GN=NUP85 PE=1 SV=1"	"0.000"	""	"9"	"5"	"11"	"5"	"656"	"75.0"	"5.55"	"1838.02"	"24.79"	"4"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07575"	"79902"	"ENSG00000125450"	"NUP85"	"B4DMQ3; B4DPW1; hsa:79902; Q8NDI4; Q9BW27; Q9H9U1"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; SUMOylation of DNA replication proteins; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; SARS-CoV-2 activates/modulates innate and adaptive immune responses; snRNP Assembly; HCMV Early Events; SUMOylation of DNA damage response and repair proteins; HCMV Late Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; Postmitotic nuclear pore complex (NPC) reformation"	""	"35"	"0"	"460.9"	"218.9"	"433.4"	"374.8"	"433.4"	"487.4"	"352.0"	"521.2"	"411.3"	"808.1"	"1191.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6UX04"	"Spliceosome-associated protein CWC27 homolog OS=Homo sapiens OX=9606 GN=CWC27 PE=1 SV=1"	"0.000"	""	"10"	"5"	"10"	"5"	"472"	"53.8"	"5.80"	"2480.52"	"24.69"	"5"	"5"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf00160"	"10283"	"ENSG00000153015"	"CWC27"	"hsa:10283; O60529; O60530; Q6UX04; Q96EM3"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"465.9"	"181.1"	"423.8"	"396.0"	"432.5"	"493.4"	"365.6"	"498.8"	"420.9"	"778.6"	"978.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NQW7"	"Xaa-Pro aminopeptidase 1 OS=Homo sapiens OX=9606 GN=XPNPEP1 PE=1 SV=3"	"0.000"	""	"14"	"7"	"12"	"7"	"623"	"69.9"	"5.67"	"1774.39"	"24.56"	"5"	"7"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00557, Pf01321, Pf16188, Pf16189"	"7511"	"ENSG00000108039"	"XPNPEP1"	"A8K071; G5E9Y2; G8JLB2; hsa:7511; O15250; Q53EX6; Q8N3Q0; Q96D23; Q9NQW7"	""	""	"0"	"0"	"203.8"	"104.2"	"180.4"	"177.8"	"210.1"	"261.0"	"305.3"	"718.2"	"794.9"	"1799.3"	"4015.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q07020"	"60S ribosomal protein L18 OS=Homo sapiens OX=9606 GN=RPL18 PE=1 SV=2"	"0.000"	""	"31"	"6"	"14"	"6"	"188"	"21.6"	"11.72"	"2372.00"	"24.54"	"6"	"6"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf17135"	"6141"	"ENSG00000063177"	"RPL18"	"F8VWC5; hsa:6141; Q07020; Q8WTZ6"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"812.4"	"333.9"	"790.4"	"678.1"	"709.0"	"852.9"	"650.9"	"815.7"	"572.3"	"1133.6"	"1747.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P78371"	"T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4"	"0.000"	""	"17"	"8"	"15"	"8"	"535"	"57.5"	"6.46"	"2805.13"	"24.53"	"8"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00118"	"10576"	"ENSG00000166226"	"CCT2"	"A8K402; B5BTY7; B7Z243; B7Z7K4; B7ZAT2; hsa:10576; P78371; Q14D36; Q6IAT3"	"Neutrophil degranulation; Association of TriC/CCT with target proteins during biosynthesis; Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle; Folding of actin by CCT/TriC"	"16p11.2 proximal deletion syndrome"	"10"	"0"	"664.5"	"293.7"	"447.1"	"367.0"	"487.7"	"523.5"	"443.2"	"512.7"	"463.4"	"729.2"	"1542.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62424"	"60S ribosomal protein L7a OS=Homo sapiens OX=9606 GN=RPL7A PE=1 SV=2"	"0.000"	""	"23"	"9"	"18"	"9"	"266"	"30.0"	"10.61"	"3564.03"	"24.32"	"9"	"7"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01248"	"6130"	"ENSG00000148303; ENSG00000280858"	"RPL7A"	"hsa:6130; P11518; P62424; Q5T8U4"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"2143.3"	"829.4"	"1916.0"	"1611.8"	"1757.0"	"2062.4"	"1452.2"	"1893.5"	"1354.0"	"2572.6"	"3812.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53396"	"ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3"	"0.000"	""	"10"	"8"	"13"	"8"	"1101"	"120.8"	"7.33"	"2635.95"	"24.23"	"7"	"6"	"other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00285, Pf00549, Pf02629, Pf16114"	"47"	"ENSG00000131473"	"ACLY"	"B4DIM0; B4E3P0; hsa:47; P53396; Q13037; Q9BRL0"	"Neutrophil degranulation; ChREBP activates metabolic gene expression; Fatty acyl-CoA biosynthesis"	"Sterol regulatory element-binding proteins (SREBP) signaling; TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Fatty acid biosynthesis; Amino acid metabolism; Lipid metabolism pathway; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer"	"10"	"0"	"395.8"	"192.4"	"402.6"	"353.9"	"384.8"	"465.5"	"338.4"	"421.3"	"327.9"	"620.2"	"1251.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A6NHR9"	"Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2"	"0.000"	""	"5"	"9"	"17"	"9"	"2005"	"226.2"	"7.30"	"3236.03"	"24.19"	"8"	"7"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06470, Pf13589"	"23347"	"ENSG00000101596"	"SMCHD1"	"A6NHR9; hsa:23347; O75141; Q6AHX6; Q6ZTQ8; Q9H6Q2; Q9UG39"	""	""	"0"	"0"	"515.8"	"209.8"	"474.2"	"381.4"	"437.6"	"522.9"	"366.0"	"544.1"	"434.7"	"880.4"	"1703.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5BKZ1"	"DBIRD complex subunit ZNF326 OS=Homo sapiens OX=9606 GN=ZNF326 PE=1 SV=2"	"0.000"	""	"11"	"5"	"12"	"5"	"582"	"65.6"	"5.15"	"2503.33"	"24.15"	"5"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04988"	"284695"	"ENSG00000162664"	"ZNF326"	"A8MYX1; B4DLN0; B4E179; hsa:284695; Q5BKZ1; Q5VW93; Q5VW94; Q5VW96; Q5VW97; Q6NSA2; Q7Z638; Q7Z6C2"	""	""	"0"	"0"	"597.5"	"161.2"	"385.5"	"298.6"	"347.4"	"401.9"	"317.2"	"393.7"	"328.3"	"585.4"	"951.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35268"	"60S ribosomal protein L22 OS=Homo sapiens OX=9606 GN=RPL22 PE=1 SV=2"	"0.000"	""	"60"	"5"	"9"	"5"	"128"	"14.8"	"9.19"	"1000.46"	"24.06"	"3"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01776"	"6146"	"ENSG00000116251"	"RPL22"	"B2R495; hsa:6146; P35268; Q6IBD1"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"271.9"	"139.8"	"244.2"	"196.9"	"232.7"	"281.5"	"213.6"	"305.0"	"285.3"	"891.3"	"834.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14978"	"Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2"	"0.000"	""	"8"	"7"	"15"	"7"	"699"	"73.6"	"9.47"	"2281.49"	"24.03"	"6"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05022"	"9221"	"ENSG00000166197"	"NOLC1"	"hsa:9221; Q14978; Q15030; Q5VV70; Q9BUV3"	""	""	"0"	"0"	"708.8"	"305.3"	"640.7"	"662.1"	"707.0"	"926.3"	"900.7"	"1647.7"	"1126.0"	"1643.4"	"2474.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62888"	"60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2"	"0.000"	""	"43"	"6"	"15"	"6"	"115"	"12.8"	"9.63"	"3086.88"	"23.93"	"6"	"5"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01248"	"6156"	"ENSG00000156482"	"RPL30"	"B2R591; hsa:6156; P04645; P62888; Q502Z6"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"700.4"	"284.9"	"574.7"	"495.4"	"551.3"	"678.2"	"478.8"	"678.7"	"494.1"	"1026.5"	"1624.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14697"	"Neutral alpha-glucosidase AB OS=Homo sapiens OX=9606 GN=GANAB PE=1 SV=3"	"0.000"	""	"10"	"7"	"10"	"7"	"944"	"106.8"	"6.14"	"1155.96"	"23.77"	"3"	"7"	"protein metabolism;other metabolic processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf01055, Pf13802"	"23193"	"ENSG00000089597"	"GANAB"	"A6NC20; hsa:23193; Q14697; Q8WTS9; Q9P0X0"	"Maturation of spike protein; Calnexin/calreticulin cycle; Maturation of spike protein"	"N-glycan biosynthesis"	"5"	"0"	"312.3"	"123.3"	"264.7"	"249.2"	"320.3"	"360.9"	"259.9"	"322.8"	"280.2"	"511.5"	"746.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y224"	"RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1"	"0.000"	""	"30"	"6"	"13"	"6"	"244"	"28.1"	"6.65"	"3046.09"	"23.75"	"6"	"5"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf10036"	"51637"	"ENSG00000087302"	"RTRAF"	"hsa:51637; Q9Y224"	"tRNA processing in the nucleus"	""	"1"	"0"	"515.1"	"182.7"	"455.8"	"360.3"	"441.4"	"497.4"	"348.7"	"488.3"	"327.5"	"689.4"	"1417.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18621"	"60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3"	"0.000"	""	"37"	"6"	"13"	"6"	"184"	"21.4"	"10.17"	"2367.55"	"23.74"	"5"	"6"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf00237"	"6139"	"ENSG00000265681"	"RPL17"	"B2R4H3; B4E3C2; B5ME31; hsa:6139; J3QL51; P18621; Q3KQW2; Q6NZ54; Q7M4M5"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"1003.3"	"326.6"	"895.8"	"766.0"	"894.4"	"1025.4"	"721.5"	"982.3"	"600.9"	"1129.2"	"1767.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95747"	"Serine/threonine-protein kinase OSR1 OS=Homo sapiens OX=9606 GN=OXSR1 PE=1 SV=1"	"0.000"	""	"15"	"4"	"6"	"4"	"527"	"58.0"	"6.43"	"550.24"	"23.74"	"1"	"4"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf12202"	"9943"	"ENSG00000172939"	"OXSR1"	"hsa:9943; O95747; Q3LR53; Q7Z501; Q9UPQ1"	""	""	"0"	"0"	"51.6"	"24.9"	"54.0"	"44.6"	"46.8"	"56.4"	"39.0"	"58.6"	"75.1"	"205.0"	"1196.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BUJ2"	"Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2"	"0.000"	""	"10"	"8"	"14"	"7"	"856"	"95.7"	"6.92"	"2310.11"	"23.52"	"6"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00622, Pf02037, Pf13671"	"11100"	"ENSG00000105323"	"HNRNPUL1"	"B3KMW7; hsa:11100; O76022; Q6ZSZ0; Q7L8P4; Q8N6Z4; Q96G37; Q9BUJ2; Q9HAL3; Q9UG75"	""	""	"0"	"0"	"671.4"	"263.4"	"594.1"	"592.1"	"610.8"	"741.0"	"535.5"	"712.5"	"468.7"	"943.6"	"1595.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14011"	"Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1"	"0.000"	""	"37"	"5"	"10"	"5"	"172"	"18.6"	"9.51"	"1421.08"	"23.49"	"3"	"5"	"cell organization and biogenesis;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"1153"	"ENSG00000099622"	"CIRBP"	"B3KT17; B4E2X2; hsa:1153; Q14011"	""	""	"0"	"0"	"701.8"	"302.7"	"569.0"	"560.8"	"548.9"	"690.3"	"548.2"	"670.0"	"540.7"	"879.6"	"1266.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55209"	"Nucleosome assembly protein 1-like 1 OS=Homo sapiens OX=9606 GN=NAP1L1 PE=1 SV=1"	"0.000"	""	"18"	"5"	"12"	"4"	"391"	"45.3"	"4.46"	"2158.90"	"23.48"	"5"	"5"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00956"	"4673"	"ENSG00000187109"	"NAP1L1"	"B3KNT8; B3KV44; hsa:4673; P55209"	""	"VEGFA-VEGFR2 signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies"	"2"	"0"	"244.3"	"122.7"	"233.5"	"201.0"	"253.8"	"302.0"	"205.7"	"280.5"	"164.9"	"319.8"	"754.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96AE4"	"Far upstream element-binding protein 1 OS=Homo sapiens OX=9606 GN=FUBP1 PE=1 SV=3"	"0.000"	""	"13"	"9"	"18"	"5"	"644"	"67.5"	"7.61"	"3068.29"	"23.44"	"9"	"7"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00013, Pf09005"	"8880"	"ENSG00000162613"	"FUBP1"	"hsa:8880; Q12828; Q96AE4"	""	""	"0"	"4"	"1460.2"	"441.6"	"937.5"	"684.9"	"976.9"	"928.7"	"787.6"	"1040.3"	"965.8"	"1742.8"	"3537.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4Z0"	"U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1"	"0.000"	""	"33"	"6"	"16"	"6"	"139"	"15.3"	"9.99"	"3255.11"	"23.23"	"6"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01423"	"25804"	"ENSG00000130520"	"LSM4"	"hsa:25804; Q9Y4Z0"	"mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease"	"Ciliary landscape"	"3"	"0"	"1164.4"	"463.7"	"965.3"	"863.3"	"965.3"	"1125.7"	"911.0"	"1128.0"	"845.6"	"1434.9"	"2071.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43447"	"Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1"	"0.000"	""	"35"	"6"	"14"	"6"	"177"	"19.2"	"8.07"	"2711.30"	"23.12"	"6"	"6"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00160"	"10465"	"ENSG00000171960"	"PPIH"	"A6NNE7; hsa:10465; O43447"	"mRNA Splicing - Major Pathway; SARS-CoV-1 activates/modulates innate immune responses"	""	"2"	"0"	"1117.4"	"498.5"	"992.5"	"993.8"	"1030.1"	"1306.2"	"1077.9"	"1338.5"	"935.1"	"2018.5"	"3505.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N684"	"Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1"	"0.000"	""	"14"	"6"	"14"	"6"	"471"	"52.0"	"8.00"	"2623.76"	"23.10"	"6"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"79869"	"ENSG00000149532"	"CPSF7"	"B3KU04; C9K0Q4; hsa:79869; Q7Z3H9; Q8N684; Q9H025; Q9H9V1"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; RHOBTB1 GTPase cycle"	""	"5"	"0"	"1252.8"	"367.5"	"685.3"	"514.8"	"657.3"	"776.7"	"709.8"	"1090.6"	"940.2"	"1585.2"	"3742.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51610"	"Host cell factor 1 OS=Homo sapiens OX=9606 GN=HCFC1 PE=1 SV=2"	"0.000"	""	"5"	"6"	"9"	"6"	"2035"	"208.6"	"7.46"	"1018.25"	"22.99"	"3"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf01344, Pf13415"	"3054"	"ENSG00000172534"	"HCFC1"	"hsa:3054; P51610; Q6P4G5"	"UCH proteinases; Formation of WDR5-containing histone-modifying complexes; Transcriptional activation of mitochondrial biogenesis; HATs acetylate histones"	"Mitochondrial gene expression; Pleural mesothelioma"	"6"	"0"	"466.1"	"166.2"	"348.2"	"284.6"	"355.0"	"347.7"	"289.7"	"385.6"	"343.7"	"610.6"	"1272.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q06330"	"Recombining binding protein suppressor of hairless OS=Homo sapiens OX=9606 GN=RBPJ PE=1 SV=3"	"0.000"	""	"23"	"8"	"13"	"8"	"500"	"55.6"	"7.18"	"2216.67"	"22.91"	"6"	"7"	"cell cycle OR cell proliferation;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09270, Pf09271, Pf20144"	"3516"	"ENSG00000168214"	"RBPJ"	"B4DY22; hsa:3516; Q06330; Q5XKH9; Q6P1N3"	"Somitogenesis; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; NOTCH1 Intracellular Domain Regulates Transcription; Formation of paraxial mesoderm; Pre-NOTCH Transcription and Translation; Notch-HLH transcription pathway; NOTCH3 Intracellular Domain Regulates Transcription; Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells; NOTCH2 intracellular domain regulates transcription; NOTCH4 Intracellular Domain Regulates Transcription; RUNX3 regulates NOTCH signaling"	"Neural crest differentiation; Notch signaling; Canonical and non-canonical Notch signaling; PTF1A related regulatory pathway; Epithelial to mesenchymal transition in colorectal cancer; Osteoblast differentiation and related diseases; Genetic causes of porto-sinusoidal vascular disease; Notch signaling pathway"	"20"	"0"	"247.7"	"133.5"	"241.5"	"218.8"	"240.1"	"254.1"	"215.6"	"309.2"	"571.8"	"2458.1"	"3364.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95400"	"CD2 antigen cytoplasmic tail-binding protein 2 OS=Homo sapiens OX=9606 GN=CD2BP2 PE=1 SV=1"	"0.000"	""	"27"	"7"	"12"	"7"	"341"	"37.6"	"4.61"	"2442.32"	"22.90"	"6"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf02213"	"10421"	"ENSG00000169217"	"CD2BP2"	"B2RDX2; hsa:10421; O95400; Q9ULP2"	""	"mRNA processing; Ciliary landscape"	"2"	"0"	"616.6"	"317.6"	"549.3"	"478.0"	"534.7"	"610.4"	"451.6"	"601.0"	"507.8"	"1089.4"	"2231.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P2T1"	"GMP reductase 2 OS=Homo sapiens OX=9606 GN=GMPR2 PE=1 SV=1"	"0.000"	""	"18"	"5"	"10"	"5"	"348"	"37.9"	"7.23"	"1334.04"	"22.84"	"3"	"5"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00478"	"51292"	"ENSG00000100938; ENSG00000284752"	"GMPR2"	"D3DS66; hsa:51292; Q567T0; Q6IAJ8; Q86T14; Q9P2T1"	"Purine salvage"	""	"1"	"0"	"134.6"	"66.2"	"129.3"	"113.1"	"140.1"	"167.9"	"231.9"	"607.6"	"831.2"	"2919.7"	"4677.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UHB6"	"LIM domain and actin-binding protein 1 OS=Homo sapiens OX=9606 GN=LIMA1 PE=1 SV=1"	"0.000"	""	"8"	"6"	"13"	"6"	"759"	"85.2"	"6.84"	"2181.96"	"22.77"	"5"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412"	"51474"	"ENSG00000050405"	"LIMA1"	"B2RB09; hsa:51474; Q2TAN7; Q59FE8; Q9BVF2; Q9H8J1; Q9HBN5; Q9NX96; Q9NXC3; Q9NXU6; Q9P0H8; Q9UHB5; Q9UHB6"	""	""	"0"	"0"	"493.8"	"211.1"	"405.9"	"371.8"	"414.6"	"465.5"	"339.9"	"438.4"	"360.5"	"730.8"	"1185.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P10599"	"Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3"	"0.000"	""	"54"	"5"	"10"	"5"	"105"	"11.7"	"4.92"	"1637.09"	"22.77"	"3"	"5"	"other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00085"	"7295"	"ENSG00000136810"	"TXN"	"B1ALW1; hsa:7295; O60744; P10599; Q53X69; Q96KI3; Q9UDG5"	"Detoxification of Reactive Oxygen Species; Oxidative Stress Induced Senescence; TP53 Regulates Metabolic Genes; Interconversion of nucleotide di- and triphosphates; The NLRP3 inflammasome; Purinergic signaling in leishmaniasis infection; Regulation of FOXO transcriptional activity by acetylation; Protein repair"	"Selenium micronutrient network; Folic acid network; Selenium micronutrient network ; Folic acid network; Selenium micronutrient network; TNF-alpha signaling pathway; Complement system; Nuclear receptors meta-pathway; NRF2 pathway; VEGFA-VEGFR2 signaling; TAR syndrome"	"19"	"0"	"1053.3"	"425.8"	"885.1"	"821.9"	"895.9"	"982.9"	"752.6"	"989.6"	"726.1"	"1377.7"	"2345.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y230"	"RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3"	"0.000"	""	"16"	"7"	"14"	"7"	"463"	"51.1"	"5.64"	"2356.56"	"22.71"	"7"	"7"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06068, Pf17856"	"10856"	"ENSG00000183207"	"RUVBL2"	"B3KQ59; E7ETE5; hsa:10856; Q6FIB9; Q6PK27; Q9Y230; Q9Y361"	"Telomere Extension By Telomerase; HATs acetylate histones"	""	"2"	"0"	"494.5"	"191.7"	"320.7"	"276.5"	"341.4"	"368.6"	"322.3"	"385.6"	"340.7"	"542.5"	"947.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43660"	"Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1"	"0.000"	""	"11"	"5"	"13"	"5"	"514"	"57.2"	"9.17"	"3203.81"	"22.69"	"5"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	""	"Pf00400"	"5356"	"ENSG00000171566"	"PLRG1"	"B3KMK4; hsa:5356; O43660; Q3KQY5; Q8WUD8"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"761.0"	"315.6"	"712.1"	"612.3"	"684.4"	"839.9"	"564.4"	"756.2"	"592.4"	"1835.4"	"3805.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P05114"	"Non-histone chromosomal protein HMG-14 OS=Homo sapiens OX=9606 GN=HMGN1 PE=1 SV=3"	""	""	"47"	"5"	"5"	"5"	"100"	"10.7"	"9.60"	""	"22.66"	""	"5"	"cell organization and biogenesis;DNA metabolism;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01101"	"3150"	"ENSG00000205581"	"HMGN1"	"hsa:3150; P05114; Q3KQR8"	"Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	"ATM signaling in development and disease ; p38 MAPK signaling pathway; Pleural mesothelioma; Nucleotide excision repair in xeroderma pigmentosum"	"8"	"0"	"198.5"	"83.2"	"165.2"	"133.0"	"154.1"	"193.7"	"128.8"	"228.8"	"231.8"	"1001.1"	"3629.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96C36"	"Pyrroline-5-carboxylate reductase 2 OS=Homo sapiens OX=9606 GN=PYCR2 PE=1 SV=1"	"0.000"	""	"20"	"5"	"9"	"5"	"320"	"33.6"	"7.77"	"1848.26"	"22.63"	"4"	"5"	"other metabolic processes;stress response"	"mitochondrion"	"other molecular function"	"Pf03807, Pf14748"	"29920"	"ENSG00000143811"	"PYCR2"	"A8K798; hsa:29920; Q7Z515; Q96C36; Q9Y5J4"	"Glutamate and glutamine metabolism"	"Metabolic reprogramming in colon cancer"	"2"	"0"	"427.0"	"173.5"	"320.1"	"282.2"	"331.9"	"387.1"	"257.7"	"395.1"	"280.0"	"558.2"	"987.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62834"	"Ras-related protein Rap-1A OS=Homo sapiens OX=9606 GN=RAP1A PE=1 SV=1"	"0.000"	""	"34"	"6"	"11"	"2"	"184"	"21.0"	"6.67"	"2114.90"	"22.63"	"5"	"6"	"cell-cell signaling;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00071"	"5906"	"ENSG00000116473"	"RAP1A"	"hsa:5906; P10113; P62834"	"Neutrophil degranulation; Signaling by BRAF and RAF1 fusions; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Rap1 signalling; Frs2-mediated activation; ARMS-mediated activation; GRB2:SOS provides linkage to MAPK signaling for Integrins ; p130Cas linkage to MAPK signaling for integrins; MET activates RAP1 and RAC1"	"Integrin-mediated cell adhesion; Thyroid stimulating hormone (TSH) signaling pathway; Androgen receptor network in prostate cancer; Brain-derived neurotrophic factor (BDNF) signaling pathway; Common pathways underlying drug addiction; Focal adhesion; Hepatocyte growth factor receptor signaling; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Ras signaling; EGF/EGFR signaling pathway; Leukocyte-intrinsic Hippo pathway functions; DNA repair pathways, full network; GDNF signaling; Interferon type I signaling pathways; Serotonin HTR1 group and FOS pathway; Serotonin receptor 4/6/7 and NR3C signaling"	"34"	"4"	"516.9"	"226.5"	"451.4"	"418.5"	"434.8"	"544.5"	"399.8"	"565.0"	"419.2"	"833.2"	"1182.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P43487"	"Ran-specific GTPase-activating protein OS=Homo sapiens OX=9606 GN=RANBP1 PE=1 SV=1"	"0.000"	""	"26"	"4"	"10"	"4"	"201"	"23.3"	"5.29"	"1303.58"	"22.47"	"3"	"4"	"transport;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00638"	"5902"	"ENSG00000099901"	"RANBP1"	"hsa:5902; P43487; Q53EY3"	"Rev-mediated nuclear export of HIV RNA"	"22q11.2 copy number variation syndrome"	"2"	"0"	"1136.1"	"372.6"	"973.8"	"890.6"	"1014.2"	"1105.1"	"786.1"	"1036.9"	"677.5"	"1499.8"	"3796.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49792"	"E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2"	"0.000"	""	"4"	"8"	"15"	"8"	"3224"	"358.0"	"6.20"	"2269.33"	"22.47"	"7"	"7"	"protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00160, Pf00638, Pf00641, Pf12185"	"5903"	"ENSG00000153201"	"RANBP2"	"hsa:5903; P49792; Q13074; Q15280; Q53TE2; Q59FH7"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; HCMV Early Events; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; HCMV Late Events; Transcriptional regulation by small RNAs; tRNA processing in the nucleus; Viral Messenger RNA Synthesis; Rev-mediated nuclear export of HIV RNA; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); SARS-CoV-2 activates/modulates innate and adaptive immune responses; Signaling by ALK fusions and activated point mutants"	""	"35"	"0"	"1137.4"	"387.3"	"889.1"	"757.0"	"853.6"	"938.8"	"700.4"	"945.5"	"710.9"	"1404.3"	"2607.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P67775"	"Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform OS=Homo sapiens OX=9606 GN=PPP2CA PE=1 SV=1"	"0.000"	""	"30"	"6"	"10"	"6"	"309"	"35.6"	"5.54"	"1210.43"	"22.45"	"4"	"6"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00149"	"5515"	"ENSG00000113575"	"PPP2CA"	"hsa:5515; P05323; P13197; P67775"	"Separation of Sister Chromatids; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Cyclin D associated events in G1; Cyclin A/B1/B2 associated events during G2/M transition; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Regulation of TP53 Degradation; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Disassembly of the destruction complex and recruitment of AXIN to the membrane; RAF activation; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; APC truncation mutants have impaired AXIN binding; AXIN missense mutants destabilize the destruction complex; Truncations of AMER1 destabilize the destruction complex; Spry regulation of FGF signaling; MASTL Facilitates Mitotic Progression; Regulation of glycolysis by fructose 2,6-bisphosphate metabolism; Initiation of Nuclear Envelope (NE) Reformation; Negative regulation of MAPK pathway; Platelet sensitization by LDL; CTLA4 inhibitory signaling; Inhibition of replication initiation of damaged DNA by RB1/E2F1; DARPP-32 events; PP2A-mediated dephosphorylation of key metabolic factors; ERKs are inactivated"	"Sphingolipid pathway; TNF-alpha signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Dopamine metabolism; Mesodermal commitment pathway; Mesodermal commitment pathway; Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Wnt signaling pathway and pluripotency; PI3K-Akt signaling pathway; Cancer immunotherapy by CTLA4 blockade; FGFR3 signaling in chondrocyte proliferation and terminal differentiation; 16p11.2 proximal deletion syndrome; Glycogen synthesis and degradation; Cohesin complex - Cornelia de Lange syndrome"	"52"	"0"	"338.3"	"146.4"	"314.6"	"281.6"	"306.3"	"356.3"	"299.9"	"381.7"	"313.0"	"617.0"	"970.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49959"	"Double-strand break repair protein MRE11 OS=Homo sapiens OX=9606 GN=MRE11 PE=1 SV=3"	"0.000"	""	"15"	"7"	"12"	"7"	"708"	"80.5"	"5.90"	"1760.25"	"22.22"	"5"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00149, Pf04152"	"4361"	"ENSG00000020922"	"MRE11"	"B3KTC7; hsa:4361; O43475; P49959"	"Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Meiotic recombination; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Resolution of D-loop Structures through Holliday Junction Intermediates; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Cytosolic sensors of pathogen-associated DNA ; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; DNA Damage/Telomere Stress Induced Senescence; Nonhomologous End-Joining (NHEJ); HDR through MMEJ (alt-NHEJ); Sensing of DNA Double Strand Breaks; IRF3-mediated induction of type I IFN"	"miRNA regulation of DNA damage response; Homologous recombination; DDX1 as a regulatory component of the Drosha microprocessor; ATM signaling in development and disease ; Breast cancer pathway; Joubert syndrome; DNA repair pathways, full network; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; Neurogenesis regulation in the olfactory epithelium; DNA damage response"	"32"	"0"	"323.9"	"134.9"	"326.2"	"291.1"	"327.6"	"378.8"	"249.1"	"368.7"	"316.2"	"884.7"	"1192.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96GM8"	"Target of EGR1 protein 1 OS=Homo sapiens OX=9606 GN=TOE1 PE=1 SV=1"	"0.000"	""	"15"	"6"	"11"	"6"	"510"	"56.5"	"7.18"	"1672.26"	"22.15"	"5"	"6"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00642, Pf04857"	"114034"	"ENSG00000132773"	"TOE1"	"B4DEM6; hsa:114034; Q6IA35; Q8IWN5; Q96GM8; Q9H846"	""	""	"0"	"0"	"534.4"	"258.9"	"505.4"	"448.1"	"483.2"	"600.8"	"388.8"	"544.5"	"406.4"	"889.1"	"1910.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95881"	"Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1"	"0.000"	""	"43"	"7"	"15"	"7"	"172"	"19.2"	"5.40"	"2921.59"	"22.10"	"6"	"5"	"other biological processes"	"ER/Golgi"	"other molecular function"	"Pf13899"	"51060"	"ENSG00000117862"	"TXNDC12"	"B3KQS0; hsa:51060; O95881; Q5T1T4; Q96H50"	""	""	"0"	"0"	"1554.2"	"859.8"	"1614.2"	"1645.8"	"1621.5"	"1880.7"	"1483.2"	"1846.1"	"1294.7"	"2102.3"	"3081.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43583"	"Density-regulated protein OS=Homo sapiens OX=9606 GN=DENR PE=1 SV=2"	"0.000"	""	"34"	"5"	"8"	"5"	"198"	"22.1"	"5.30"	"875.14"	"21.98"	"1"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	""	"nucleic acid binding activity"	"Pf01253"	"8562"	"ENSG00000139726"	"DENR"	"hsa:8562; O43583; Q9H3U6; Q9UKZ0"	""	""	"0"	"0"	"436.6"	"189.3"	"396.1"	"322.3"	"397.1"	"409.5"	"345.1"	"492.0"	"405.2"	"1028.8"	"3256.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19447"	"General transcription and DNA repair factor IIH helicase subunit XPB OS=Homo sapiens OX=9606 GN=ERCC3 PE=1 SV=1"	"0.000"	""	"9"	"5"	"9"	"5"	"782"	"89.2"	"7.23"	"929.34"	"21.94"	"2"	"5"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04851, Pf13625, Pf16203"	"2071"	"ENSG00000163161"	"ERCC3"	"hsa:2071; P19447; Q53QM0"	"Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; Formation of Incision Complex in GG-NER; Dual Incision in GG-NER"	"Eukaryotic transcription initiation; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"33"	"0"	"162.6"	"76.6"	"129.0"	"127.0"	"130.6"	"151.1"	"144.6"	"291.1"	"507.8"	"1238.6"	"1546.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TEA8"	"D-aminoacyl-tRNA deacylase 1 OS=Homo sapiens OX=9606 GN=DTD1 PE=1 SV=2"	"0.000"	""	"38"	"5"	"7"	"5"	"209"	"23.4"	"8.24"	"1023.78"	"21.93"	"2"	"5"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02580"	"92675"	"ENSG00000125821"	"DTD1"	"A8K5X5; D3DW37; hsa:92675; Q496D1; Q5W184; Q8TEA8; Q8WXU8; Q9BW67; Q9H464; Q9H474"	""	""	"0"	"0"	"142.3"	"59.7"	"130.0"	"109.0"	"133.6"	"152.7"	"127.9"	"253.2"	"398.6"	"2702.7"	"3983.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P16104"	"Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2"	"0.000"	""	"27"	"3"	"11"	"1"	"143"	"15.1"	"10.74"	"1196.82"	"21.86"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125, Pf16211"	"3014"	"ENSG00000188486"	"H2AX"	"hsa:3014; P16104; Q4ZGJ7; Q6IAS5"	"RUNX1 regulates transcription of genes involved in differentiation of HSCs; RMTs methylate histone arginines; Amyloid fiber formation; Meiotic synapsis; Transcriptional regulation by small RNAs; Deposition of new CENPA-containing nucleosomes at the centromere; B-WICH complex positively regulates rRNA expression; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Formation of the beta-catenin:TCF transactivating complex; Oxidative Stress Induced Senescence; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Pre-NOTCH Transcription and Translation; Senescence-Associated Secretory Phenotype (SASP); RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; RNA Polymerase I Promoter Escape; Meiotic recombination; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Packaging Of Telomere Ends; Condensation of Prophase Chromosomes; DNA Damage/Telomere Stress Induced Senescence; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; Nonhomologous End-Joining (NHEJ); RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	"miRNA regulation of DNA damage response; miRNAs involved in DNA damage response; Proteasome degradation; ATM signaling in development and disease ; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; DNA repair pathways, full network; 5q35 copy number variation; DNA damage response"	"46"	"0"	"100.3"	"55.8"	"75.0"	"55.2"	"70.1"	"75.2"	"67.0"	"83.0"	"72.1"	"102.8"	"128.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6PD62"	"RNA polymerase-associated protein CTR9 homolog OS=Homo sapiens OX=9606 GN=CTR9 PE=1 SV=1"	"0.001"	""	"5"	"4"	"5"	"4"	"1173"	"133.4"	"6.77"	"273.50"	"21.83"	"1"	"3"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf13181"	"9646"	"ENSG00000198730"	"CTR9"	"D3DQV8; hsa:9646; Q15015; Q6PD62"	"E3 ubiquitin ligases ubiquitinate target proteins; Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events"	"Endoderm differentiation"	"5"	"0"	"230.1"	"94.8"	"196.5"	"201.7"	"213.3"	"249.3"	"172.4"	"261.8"	"185.6"	"366.1"	"712.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q2NL82"	"Pre-rRNA-processing protein TSR1 homolog OS=Homo sapiens OX=9606 GN=TSR1 PE=1 SV=1"	"0.000"	""	"11"	"8"	"15"	"8"	"804"	"91.8"	"7.42"	"2657.89"	"21.78"	"8"	"7"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04950, Pf08142"	"55720"	"ENSG00000167721"	"TSR1"	"hsa:55720; Q2NL82; Q8WUY5; Q9NVT0; Q9P2E6"	"Major pathway of rRNA processing in the nucleolus and cytosol"	""	"1"	"0"	"790.5"	"315.2"	"702.4"	"608.2"	"666.4"	"815.6"	"611.6"	"986.5"	"785.7"	"1871.8"	"2694.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60869"	"Endothelial differentiation-related factor 1 OS=Homo sapiens OX=9606 GN=EDF1 PE=1 SV=1"	"0.000"	""	"47"	"8"	"14"	"8"	"148"	"16.4"	"9.95"	"2316.21"	"21.76"	"7"	"7"	"other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01381, Pf08523"	"8721"	"ENSG00000107223"	"EDF1"	"hsa:8721; O60869; Q5T5T2; Q9UIM1"	""	""	"0"	"0"	"1793.2"	"878.7"	"1916.8"	"1617.5"	"1697.6"	"2094.7"	"1507.6"	"1986.3"	"1270.1"	"3361.2"	"5320.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95347"	"Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2"	"0.000"	""	"6"	"6"	"12"	"6"	"1197"	"135.6"	"8.43"	"2269.35"	"21.50"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463, Pf06470"	"10592"	"ENSG00000136824"	"SMC2"	"hsa:10592; O95347; Q6IEE0; Q9P1P2"	"Condensation of Prophase Chromosomes; Condensation of Prometaphase Chromosomes"	"Retinoblastoma gene in cancer"	"3"	"0"	"292.3"	"145.3"	"281.2"	"221.4"	"251.7"	"268.5"	"199.9"	"275.9"	"249.1"	"673.7"	"1182.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55081"	"Microfibrillar-associated protein 1 OS=Homo sapiens OX=9606 GN=MFAP1 PE=1 SV=2"	"0.000"	""	"14"	"7"	"13"	"6"	"439"	"51.9"	"4.98"	"2045.66"	"21.40"	"6"	"6"	"RNA metabolism OR transcription;other metabolic processes"	"extracellular matrix;cytoskeleton;nucleus"	""	"Pf06991"	"4236"	"ENSG00000140259"	"MFAP1"	"hsa:4236; P55081; Q86TG6"	"mRNA Splicing - Major Pathway"	"Canonical and non-canonical Notch signaling; Ciliary landscape"	"3"	"0"	"827.4"	"289.4"	"616.8"	"549.0"	"646.7"	"738.2"	"613.4"	"800.7"	"549.3"	"971.6"	"1566.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P48643"	"T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1"	"0.000"	""	"11"	"7"	"15"	"7"	"541"	"59.6"	"5.66"	"2973.96"	"21.39"	"7"	"6"	"protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00118"	"22948"	"ENSG00000150753"	"CCT5"	"A8JZY8; A8K2X8; B4DYD8; hsa:22948; P48643"	"Prefoldin mediated transfer of substrate  to CCT/TriC; Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Folding of actin by CCT/TriC"	"16p11.2 proximal deletion syndrome"	"7"	"0"	"1603.5"	"606.7"	"1385.3"	"1070.9"	"1348.1"	"1517.2"	"1095.7"	"1436.6"	"1029.0"	"1898.8"	"3765.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P33240"	"Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1"	"0.000"	""	"15"	"6"	"11"	"6"	"577"	"60.9"	"6.83"	"1792.12"	"21.37"	"5"	"6"	"other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf14304, Pf14327"	"1478"	"ENSG00000101811"	"CSTF2"	"hsa:1478; P33240; Q5H951; Q6LA74; Q8N502"	"tRNA processing in the nucleus; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"mRNA processing"	"6"	"0"	"767.1"	"267.5"	"652.6"	"557.7"	"643.2"	"705.2"	"501.7"	"643.2"	"474.1"	"935.9"	"1652.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14854"	"Cytochrome c oxidase subunit 6B1 OS=Homo sapiens OX=9606 GN=COX6B1 PE=1 SV=2"	"0.000"	""	"49"	"4"	"8"	"4"	"86"	"10.2"	"7.05"	"961.01"	"21.31"	"2"	"4"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf02297"	"1340"	"ENSG00000126267"	"COX6B1"	"B2R5C9; hsa:1340; P14854; Q6IBL4"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly; 5q35 copy number variation"	"7"	"0"	"330.4"	"185.3"	"316.3"	"337.7"	"330.6"	"377.9"	"322.9"	"376.1"	"277.5"	"479.1"	"812.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P12277"	"Creatine kinase B-type OS=Homo sapiens OX=9606 GN=CKB PE=1 SV=1"	"0.000"	""	"15"	"4"	"8"	"4"	"381"	"42.6"	"5.59"	"1164.13"	"21.30"	"3"	"4"	"other metabolic processes;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00217, Pf02807"	"1152"	"ENSG00000166165"	"CKB"	"A8K236; B2R5R4; hsa:1152; P12277; Q2LE07; Q6FG40; Q9UC66"	"RND3 GTPase cycle; Creatine metabolism"	""	"2"	"0"	"434.5"	"133.1"	"218.0"	"153.1"	"257.4"	"249.1"	"250.2"	"262.7"	"333.1"	"448.6"	"893.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99543"	"DnaJ homolog subfamily C member 2 OS=Homo sapiens OX=9606 GN=DNAJC2 PE=1 SV=4"	"0.000"	""	"12"	"6"	"10"	"6"	"621"	"72.0"	"8.70"	"1571.54"	"21.25"	"4"	"6"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"translation activity;other molecular function"	"Pf00226, Pf00249, Pf16717"	"27000"	"ENSG00000105821"	"DNAJC2"	"A4VCI0; hsa:27000; Q99543; Q9BVX1"	"Regulation of HSF1-mediated heat shock response"	""	"1"	"0"	"172.3"	"81.7"	"156.5"	"134.9"	"153.6"	"170.6"	"137.2"	"217.7"	"222.7"	"1212.4"	"2920.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P33993"	"DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4"	"0.000"	""	"13"	"6"	"12"	"6"	"719"	"81.3"	"6.46"	"2344.32"	"21.09"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855"	"4176"	"ENSG00000166508"	"MCM7"	"A4D2A1; A4D2A2; E9PGN9; hsa:4176; P33993; Q15076; Q96D34; Q96GL1"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"miRNA regulation of DNA damage response; Cell cycle; Retinoblastoma gene in cancer; Ciliary landscape; G1 to S cell cycle control; DNA replication"	"12"	"0"	"406.4"	"157.6"	"306.8"	"269.3"	"311.6"	"381.7"	"374.5"	"526.3"	"418.3"	"594.2"	"998.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46060"	"Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1"	"0.000"	""	"14"	"8"	"11"	"8"	"587"	"63.5"	"4.68"	"1381.03"	"21.04"	"4"	"7"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf07834, Pf13516"	"5905"	"ENSG00000100401"	"RANGAP1"	"hsa:5905; P46060; Q96JJ2"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Rev-mediated nuclear export of HIV RNA; SUMOylation of DNA replication proteins; Postmitotic nuclear pore complex (NPC) reformation; SUMOylation of nuclear envelope proteins"	"22q11.2 copy number variation syndrome; IL-18 signaling pathway"	"12"	"0"	"615.8"	"283.2"	"579.1"	"482.1"	"554.5"	"646.7"	"475.2"	"634.6"	"489.4"	"1017.5"	"1852.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IWS0"	"PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1"	"0.000"	""	"16"	"5"	"9"	"5"	"365"	"41.3"	"8.68"	"1013.46"	"21.03"	"2"	"5"	"developmental processes;other biological processes"	"nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf13771"	"84295"	"ENSG00000156531"	"PHF6"	"A8K230; B4E0G4; D3DTG3; E9PC97; hsa:84295; Q5JRC7; Q5JRC8; Q8IWS0; Q96JK3; Q9BRU0"	""	"Mesodermal commitment pathway"	"1"	"0"	"207.7"	"90.9"	"196.8"	"160.4"	"206.0"	"206.1"	"162.1"	"256.3"	"220.2"	"1320.2"	"3734.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NZJ9"	"Diphosphoinositol polyphosphate phosphohydrolase 2 OS=Homo sapiens OX=9606 GN=NUDT4 PE=1 SV=2"	"0.000"	""	"29"	"7"	"12"	"2"	"180"	"20.3"	"6.35"	"1737.77"	"21.03"	"4"	"7"	"other metabolic processes;signal transduction"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00293"	"11163"	"ENSG00000173598"	"NUDT4"	"B7Z916; hsa:11163; Q4AEJ6; Q53EZ2; Q68DD7; Q9NPC5; Q9NS30; Q9NZJ9; Q9NZK0; Q9NZK1"	"Synthesis of pyrophosphates in the cytosol"	""	"1"	"0"	"41.2"	"18.3"	"48.7"	"127.0"	"67.8"	"271.8"	"357.3"	"458.0"	"375.7"	"630.0"	"893.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92738"	"USP6 N-terminal-like protein OS=Homo sapiens OX=9606 GN=USP6NL PE=1 SV=3"	"0.000"	""	"6"	"4"	"12"	"4"	"828"	"94.0"	"9.07"	"2558.37"	"20.89"	"4"	"4"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00566"	"9712"	"ENSG00000148429"	"USP6NL"	"A8KA79; hsa:9712; Q15400; Q5VV10; Q7L0K9; Q92738"	"Retrograde transport at the Trans-Golgi-Network"	"EGF/EGFR signaling pathway"	"2"	"0"	"133.0"	"55.7"	"111.0"	"126.8"	"120.7"	"192.4"	"297.1"	"689.2"	"852.6"	"1144.6"	"638.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15637"	"Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4"	"0.000"	""	"10"	"4"	"9"	"4"	"639"	"68.3"	"8.98"	"1577.64"	"20.69"	"3"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"translational apparatus;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf00098, Pf16275"	"7536"	"ENSG00000168066"	"SF1"	"B7Z1Q1; C9JJE2; hsa:7536; Q14818; Q14819; Q15637; Q15913; Q8IY00; Q92744; Q92745; Q969H7; Q9BW01; Q9UEI0"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"507.1"	"186.7"	"432.2"	"360.6"	"435.8"	"494.0"	"348.5"	"418.3"	"330.7"	"672.4"	"1439.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51659"	"Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3"	"0.000"	""	"13"	"6"	"10"	"6"	"736"	"79.6"	"8.84"	"1478.06"	"20.67"	"4"	"6"	"other metabolic processes;developmental processes"	"cytosol;other cytoplasmic organelle"	"other molecular function"	"Pf00106, Pf01575, Pf02036"	"3295"	"ENSG00000133835"	"HSD17B4"	"B4DNV1; B4DVS5; E9PB82; F5HE57; hsa:3295; P51659"	"TYSND1 cleaves peroxisomal proteins; Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol; alpha-linolenic acid (ALA) metabolism; Beta-oxidation of pristanoyl-CoA; Beta-oxidation of very long chain fatty acids"	"Androgen receptor network in prostate cancer; Steroid biosynthesis; Disorders of bile acid synthesis and biliary transport; Primary ovarian insufficiency"	"10"	"0"	"462.3"	"206.2"	"386.8"	"290.6"	"346.9"	"439.1"	"310.7"	"386.0"	"325.5"	"869.7"	"1832.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62280"	"40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3"	"0.000"	""	"32"	"6"	"14"	"6"	"158"	"18.4"	"10.30"	"2361.64"	"20.60"	"6"	"6"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00366, Pf16205"	"6205"	"ENSG00000142534"	"RPS11"	"B2R4F5; hsa:6205; P04643; P62280; Q498Y6; Q6IRY0"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"VEGFA-VEGFR2 signaling; IL-18 signaling pathway; Cytoplasmic ribosomal proteins"	"21"	"0"	"1511.6"	"694.1"	"1445.4"	"1465.1"	"1404.1"	"1686.3"	"1237.8"	"1483.1"	"1087.3"	"2023.2"	"3502.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14314"	"Glucosidase 2 subunit beta OS=Homo sapiens OX=9606 GN=PRKCSH PE=1 SV=2"	"0.000"	""	"12"	"7"	"11"	"7"	"528"	"59.4"	"4.41"	"2338.97"	"20.60"	"6"	"5"	"protein metabolism;other metabolic processes;developmental processes;signal transduction"	"ER/Golgi;other cell component"	"other molecular function"	"Pf12999, Pf13015, Pf13202"	"5589"	"ENSG00000130175"	"PRKCSH"	"A8K318; hsa:5589; P14314; Q96BU9; Q96D06; Q9P0W9"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Advanced glycosylation endproduct receptor signaling; Maturation of spike protein; Calnexin/calreticulin cycle; Maturation of spike protein"	""	"7"	"0"	"1054.1"	"427.7"	"1030.1"	"847.7"	"1079.1"	"1132.7"	"804.6"	"1101.0"	"804.9"	"1403.4"	"2204.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NZI8"	"Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2"	"0.000"	""	"12"	"6"	"11"	"5"	"577"	"63.4"	"9.20"	"2539.80"	"20.59"	"6"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf00076"	"10642"	"ENSG00000159217"	"IGF2BP1"	"C9JT33; hsa:10642; Q9NZI8"	"MAPK6/MAPK4 signaling; Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; eIF5A regulation in response to inhibition of the nuclear export system"	"4"	"1"	"1071.9"	"282.2"	"702.9"	"559.1"	"631.3"	"753.5"	"561.0"	"767.8"	"587.6"	"1056.5"	"2003.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15084"	"Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1"	"0.000"	""	"20"	"6"	"11"	"6"	"440"	"48.1"	"5.08"	"2152.94"	"20.56"	"5"	"6"	"protein metabolism;other metabolic processes;stress response"	"non-structural extracellular;plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00085"	"10130"	"ENSG00000143870"	"PDIA6"	"B3KY95; B5MCQ5; B7Z254; B7Z4M8; F8WA83; hsa:10130; Q15084; Q53RC7; Q6ZSH5; Q99778"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; XBP1(S) activates chaperone genes"	"Photodynamic therapy-induced unfolded protein response; VEGFA-VEGFR2 signaling"	"5"	"0"	"518.7"	"296.5"	"539.8"	"522.8"	"490.3"	"628.0"	"401.4"	"586.3"	"401.6"	"630.0"	"1109.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55769"	"NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3"	"0.000"	""	"62"	"5"	"8"	"5"	"128"	"14.2"	"8.46"	"1043.12"	"20.48"	"3"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01248"	"4809"	"ENSG00000100138"	"SNU13"	"hsa:4809; P55769"	"mRNA Splicing - Major Pathway; Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"mRNA processing"	"4"	"0"	"190.8"	"70.5"	"189.5"	"152.5"	"165.2"	"225.4"	"168.8"	"256.2"	"194.0"	"706.8"	"1649.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P12236"	"ADP/ATP translocase 3 OS=Homo sapiens OX=9606 GN=SLC25A6 PE=1 SV=4"	"0.000"	""	"19"	"6"	"14"	"1"	"298"	"32.8"	"9.74"	"2300.45"	"20.46"	"6"	"6"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity"	"Pf00153"	"293"	"ENSG00000169100"	"SLC25A6"	"hsa:293; P12236; Q96C49"	"Mitochondrial protein import; Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane; Influenza Virus Induced Apoptosis; Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization"	"Electron transport chain: OXPHOS system in mitochondria; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"7"	"0"	"87.8"	"26.1"	"85.5"	"56.5"	"82.4"	"71.8"	"73.9"	"84.7"	"57.1"	"155.2"	"392.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y314"	"Nitric oxide synthase-interacting protein OS=Homo sapiens OX=9606 GN=NOSIP PE=1 SV=1"	"0.000"	""	"20"	"4"	"9"	"4"	"301"	"33.2"	"8.82"	"1760.74"	"20.32"	"3"	"4"	"other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf15906"	"51070"	"ENSG00000142546"	"NOSIP"	"hsa:51070; Q96FD2; Q9Y314"	"NOSIP mediated eNOS trafficking"	""	"1"	"0"	"252.9"	"96.1"	"207.1"	"178.6"	"215.1"	"227.6"	"171.4"	"280.1"	"289.1"	"1097.4"	"2348.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L576"	"Cytoplasmic FMR1-interacting protein 1 OS=Homo sapiens OX=9606 GN=CYFIP1 PE=1 SV=1"	"0.000"	""	"5"	"7"	"13"	"4"	"1253"	"145.1"	"6.90"	"2735.79"	"20.32"	"7"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf05994, Pf07159"	"23191"	"ENSG00000273749; ENSG00000288461"	"CYFIP1"	"A8K6D9; hsa:23191; Q14467; Q5IED0; Q6ZSX1; Q7L576; Q9BSD9; Q9BVC7"	"Neutrophil degranulation; VEGFA-VEGFR2 Pathway; RAC3 GTPase cycle; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RAC1 GTPase cycle; RHOG GTPase cycle; RHO GTPases Activate WASPs and WAVEs; RAC2 GTPase cycle"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; Prader-Willi and Angelman syndrome; Fragile X syndrome; Disruption of postsynaptic signaling by CNV; 15q11.2 copy number variation syndrome; G13 signaling pathway"	"15"	"3"	"246.4"	"106.9"	"249.0"	"207.0"	"229.7"	"291.1"	"262.5"	"396.6"	"358.3"	"1025.3"	"2375.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13825"	"Methylglutaconyl-CoA hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=AUH PE=1 SV=1"	"0.000"	""	"18"	"5"	"11"	"5"	"339"	"35.6"	"9.48"	"1782.88"	"20.28"	"4"	"5"	"other metabolic processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00378"	"549"	"ENSG00000148090"	"AUH"	"B1ALV7; B1ALV8; hsa:549; Q13825; Q8WUE4"	"Branched-chain amino acid catabolism"	"Amino acid metabolism"	"2"	"0"	"537.5"	"223.6"	"462.7"	"365.5"	"439.6"	"516.2"	"449.8"	"678.0"	"850.8"	"3039.5"	"1748.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43427"	"Acidic fibroblast growth factor intracellular-binding protein OS=Homo sapiens OX=9606 GN=FIBP PE=1 SV=3"	"0.000"	""	"20"	"9"	"17"	"9"	"364"	"41.9"	"6.48"	"3213.50"	"20.26"	"9"	"6"	"signal transduction"	"other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf05427"	"9158"	"ENSG00000172500"	"FIBP"	"A8K0J7; hsa:9158; O43427; Q27Q85; Q6IBQ3; Q9HD65"	""	"Modulators of TCR signaling and T cell activation"	"1"	"0"	"358.2"	"155.6"	"384.2"	"317.9"	"359.6"	"740.5"	"1080.2"	"2221.0"	"2260.1"	"4848.3"	"6382.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6UXN9"	"WD repeat-containing protein 82 OS=Homo sapiens OX=9606 GN=WDR82 PE=1 SV=1"	"0.000"	""	"18"	"5"	"10"	"5"	"313"	"35.1"	"7.69"	"1051.75"	"20.02"	"3"	"5"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00400"	"80335"	"ENSG00000164091"	"WDR82"	"A8K5R5; hsa:80335; Q6UXN9; Q8TEB2"	"Formation of WDR5-containing histone-modifying complexes"	""	"1"	"0"	"820.7"	"394.9"	"746.3"	"725.4"	"754.3"	"1001.1"	"826.1"	"1046.4"	"876.1"	"1519.4"	"2539.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96SB8"	"Structural maintenance of chromosomes protein 6 OS=Homo sapiens OX=9606 GN=SMC6 PE=1 SV=2"	"0.000"	""	"6"	"4"	"8"	"4"	"1091"	"126.2"	"6.99"	"1315.49"	"19.92"	"2"	"4"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463"	"79677"	"ENSG00000163029"	"SMC6"	"A8K8Q6; D6W518; hsa:79677; Q05BV4; Q96SB8; Q9H0X3; Q9H6M0"	"SUMOylation of DNA damage response and repair proteins"	""	"1"	"0"	"130.9"	"56.1"	"107.9"	"85.0"	"102.9"	"137.8"	"87.7"	"114.5"	"108.5"	"253.0"	"657.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16891"	"MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1"	"0.000"	""	"8"	"7"	"15"	"7"	"758"	"83.6"	"6.48"	"2772.93"	"19.86"	"7"	"6"	"cell organization and biogenesis;other biological processes"	"other membranes;mitochondrion"	""	"Pf09731"	"10989"	"ENSG00000132305"	"IMMT"	"B1H0U5; B2R5N6; hsa:10989; Q14539; Q15092; Q16891; Q68D41; Q69HW5; Q6IBL0; Q7Z3X1; Q8TAJ5; Q9P0V2"	"Cristae formation"	""	"1"	"0"	"2372.9"	"460.2"	"1037.9"	"791.5"	"1199.0"	"1109.4"	"909.4"	"1233.1"	"1027.9"	"2224.2"	"4852.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NY12"	"H/ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1"	"0.000"	""	"21"	"6"	"10"	"6"	"217"	"22.3"	"10.92"	"1292.68"	"19.86"	"4"	"6"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf04410"	"54433"	"ENSG00000109534"	"GAR1"	"hsa:54433; Q5MJQ2; Q9NY12"	"rRNA modification in the nucleus and cytosol; Telomere Extension By Telomerase"	""	"2"	"0"	"373.2"	"140.7"	"313.2"	"250.7"	"298.2"	"360.8"	"285.7"	"437.4"	"409.5"	"2042.8"	"3570.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BZ29"	"Dedicator of cytokinesis protein 9 OS=Homo sapiens OX=9606 GN=DOCK9 PE=1 SV=2"	"0.000"	""	"5"	"7"	"13"	"6"	"2069"	"236.3"	"7.49"	"2624.66"	"19.81"	"7"	"6"	"signal transduction;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity"	"Pf00169, Pf06920, Pf11878, Pf14429, Pf20421, Pf20422"	"23348"	"ENSG00000088387"	"DOCK9"	"B3KX25; E9PFM9; hsa:23348; Q5JUD4; Q5JUD6; Q5T2Q1; Q5TAN8; Q9BZ25; Q9BZ26; Q9BZ27; Q9BZ28; Q9BZ29; Q9UPU4"	"CDC42 GTPase cycle; RAC1 GTPase cycle; Factors involved in megakaryocyte development and platelet production"	""	"3"	"0"	"85.5"	"36.9"	"61.8"	"67.5"	"73.3"	"170.2"	"243.2"	"572.1"	"461.8"	"835.2"	"672.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14498"	"RNA-binding protein 39 OS=Homo sapiens OX=9606 GN=RBM39 PE=1 SV=2"	"0.000"	""	"13"	"6"	"11"	"6"	"530"	"59.3"	"10.10"	"1878.24"	"19.79"	"5"	"6"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00076, Pf15519"	"9584"	"ENSG00000131051"	"RBM39"	"A2RRD3; A5D8W2; B0BLV3; E1P5S0; E1P5S1; hsa:9584; Q14498; Q14499"	"mRNA Splicing - Major Pathway"	"VEGFA-VEGFR2 signaling; mRNA processing"	"3"	"0"	"1070.5"	"313.7"	"638.6"	"547.4"	"624.2"	"686.8"	"536.5"	"751.7"	"670.4"	"1243.4"	"2027.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NFH3"	"Nucleoporin Nup43 OS=Homo sapiens OX=9606 GN=NUP43 PE=1 SV=1"	"0.000"	""	"10"	"4"	"10"	"4"	"380"	"42.1"	"5.63"	"2142.19"	"19.78"	"4"	"4"	"cell cycle OR cell proliferation;transport;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00400"	"348995"	"ENSG00000120253"	"NUP43"	"B4E2F0; hsa:348995; Q8NFH3; Q9H8S0"	"Regulation of HSF1-mediated heat shock response; RHO GTPases Activate Formins; Transport of Mature mRNA derived from an Intron-Containing Transcript; ISG15 antiviral mechanism; HCMV Late Events; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; HCMV Early Events; EML4 and NUDC in mitotic spindle formation; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Postmitotic nuclear pore complex (NPC) reformation"	""	"35"	"0"	"340.4"	"166.8"	"324.7"	"291.3"	"308.1"	"346.1"	"266.9"	"332.5"	"260.5"	"762.8"	"1894.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46781"	"40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3"	"0.000"	""	"28"	"8"	"16"	"8"	"194"	"22.6"	"10.65"	"2667.29"	"19.75"	"8"	"6"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00163, Pf01479"	"6203"	"ENSG00000170889; ENSG00000274005; ENSG00000274626; ENSG00000274646; ENSG00000274950; ENSG00000275323; ENSG00000277079; ENSG00000277359; ENSG00000278081; ENSG00000278270"	"RPS9"	"A9C4C1; hsa:6203; P46781; Q4QRK7; Q9BVZ0"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"20"	"0"	"1227.2"	"451.2"	"1053.8"	"920.0"	"991.9"	"1245.5"	"1052.7"	"1268.4"	"1191.6"	"2025.3"	"2982.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95232"	"Luc7-like protein 3 OS=Homo sapiens OX=9606 GN=LUC7L3 PE=1 SV=2"	"0.000"	""	"12"	"6"	"14"	"6"	"432"	"51.4"	"9.79"	"2189.02"	"19.69"	"6"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf03194"	"51747"	"ENSG00000108848"	"LUC7L3"	"B3KN54; D3DTY1; hsa:51747; O95232; Q6PHR9; Q9NUY0; Q9P2S7"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"1973.5"	"459.9"	"1063.0"	"944.8"	"1105.0"	"1295.0"	"1014.2"	"1880.6"	"1300.8"	"2210.9"	"4015.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NTI5"	"Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens OX=9606 GN=PDS5B PE=1 SV=1"	"0.000"	""	"5"	"5"	"9"	"4"	"1447"	"164.6"	"8.47"	"1478.63"	"19.67"	"4"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf20168"	"23047"	"ENSG00000083642"	"PDS5B"	"hsa:23047; Q5R3S3; Q5W0K8; Q6NSC3; Q8IXT6; Q9H5N8; Q9NTI5; Q9Y2I5; Q9Y451"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"Cohesin complex - Cornelia de Lange syndrome; 10q22q23 copy number variation"	"6"	"1"	"310.1"	"121.4"	"250.7"	"224.7"	"243.8"	"273.4"	"224.3"	"332.1"	"225.9"	"546.4"	"1375.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16630"	"Cleavage and polyadenylation specificity factor subunit 6 OS=Homo sapiens OX=9606 GN=CPSF6 PE=1 SV=2"	"0.000"	""	"15"	"5"	"7"	"5"	"551"	"59.2"	"7.15"	"1198.24"	"19.63"	"3"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00076"	"11052"	"ENSG00000111605"	"CPSF6"	"A8K7K9; hsa:11052; Q16630; Q53ES1; Q9BSJ7; Q9BW18"	"Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease"	""	"2"	"0"	"431.9"	"134.7"	"242.4"	"204.6"	"230.0"	"380.9"	"379.4"	"681.1"	"525.6"	"569.6"	"1310.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96SI9"	"Spermatid perinuclear RNA-binding protein OS=Homo sapiens OX=9606 GN=STRBP PE=1 SV=1"	"0.000"	""	"9"	"5"	"10"	"1"	"672"	"73.6"	"8.72"	"2178.48"	"19.63"	"5"	"5"	"other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity"	"Pf00035, Pf07528"	"55342"	"ENSG00000165209"	"STRBP"	"hsa:55342; Q32NB9; Q96SI9; Q9BUE1; Q9BXG4; Q9H0B4; Q9H7V1; Q9NUK4"	""	""	"0"	"0"	"138.4"	"44.4"	"106.5"	"77.3"	"99.2"	"106.0"	"82.0"	"109.7"	"90.8"	"179.9"	"433.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H4G4"	"Golgi-associated plant pathogenesis-related protein 1 OS=Homo sapiens OX=9606 GN=GLIPR2 PE=1 SV=3"	"0.000"	""	"46"	"5"	"10"	"5"	"154"	"17.2"	"9.41"	"2179.24"	"19.57"	"4"	"4"	"other biological processes"	"non-structural extracellular;other membranes;ER/Golgi"	"other molecular function"	"Pf00188"	"152007"	"ENSG00000122694"	"GLIPR2"	"hsa:152007; Q5VZR1; Q8N2S6; Q8WWC9; Q8WX36; Q9H4G4"	""	""	"0"	"0"	"1173.2"	"570.3"	"901.0"	"768.9"	"881.3"	"985.5"	"855.6"	"1160.1"	"1006.6"	"2189.7"	"1959.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVI7"	"ATPase family AAA domain-containing protein 3A OS=Homo sapiens OX=9606 GN=ATAD3A PE=1 SV=2"	"0.000"	""	"11"	"6"	"10"	"3"	"634"	"71.3"	"8.98"	"1254.15"	"19.56"	"4"	"6"	"cell organization and biogenesis;stress response;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf00004, Pf12037"	"55210"	"ENSG00000197785"	"ATAD3A"	"B3KPB3; D2K8Q1; G3V1I6; hsa:55210; Q5SV23; Q8N275; Q96A50; Q9NVI7"	""	"1p36 copy number variation syndrome"	"1"	"3"	"589.9"	"208.6"	"439.0"	"353.3"	"411.1"	"471.6"	"349.9"	"484.4"	"377.0"	"809.1"	"1588.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NUP9"	"Protein lin-7 homolog C OS=Homo sapiens OX=9606 GN=LIN7C PE=1 SV=1"	"0.000"	""	"28"	"8"	"16"	"4"	"197"	"21.8"	"8.43"	"2892.13"	"19.52"	"8"	"6"	"cell-cell signaling;transport;other biological processes"	"plasma membrane;other membranes;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00595, Pf02828"	"55327"	"ENSG00000148943"	"LIN7C"	"hsa:55327; Q9NUP9"	"Neurexins and neuroligins; Assembly and cell surface presentation of NMDA receptors; Dopamine Neurotransmitter Release Cycle"	""	"3"	"4"	"1216.5"	"540.9"	"1084.0"	"873.0"	"1153.4"	"1275.3"	"997.3"	"1295.1"	"972.7"	"1997.9"	"4103.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16775"	"Hydroxyacylglutathione hydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=HAGH PE=1 SV=2"	"0.000"	""	"19"	"4"	"8"	"4"	"308"	"33.8"	"8.12"	"1098.15"	"19.51"	"3"	"4"	"other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00753, Pf16123"	"3029"	"ENSG00000063854"	"HAGH"	"A8K290; B4DP33; B4DRA7; E7EN93; hsa:3029; Q16775"	""	""	"0"	"0"	"140.6"	"59.8"	"114.8"	"104.9"	"130.3"	"180.6"	"114.9"	"169.7"	"128.0"	"186.5"	"373.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P60174"	"Triosephosphate isomerase OS=Homo sapiens OX=9606 GN=TPI1 PE=1 SV=3"	"0.000"	""	"22"	"5"	"10"	"5"	"286"	"30.8"	"5.92"	"2321.64"	"19.47"	"5"	"5"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00121"	""	"ENSPPYG00000004207; ENSPTRG00000004595"	"TPI1"	"A0A2J8JEI5; A0A2J8JEJ3; A0A2J8TBG7; A0A6D2X563; H2NGA4"	""	""	"0"	"0"	"781.3"	"175.8"	"378.4"	"168.0"	"425.5"	"295.8"	"391.9"	"390.8"	"531.5"	"705.4"	"1607.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62266"	"40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3"	"0.000"	""	"36"	"4"	"12"	"4"	"143"	"15.8"	"10.49"	"2062.42"	"19.40"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00164"	"6228"	"ENSG00000186468"	"RPS23"	"hsa:6228; P39028; P62266; Q6IB08"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"1095.5"	"527.8"	"930.2"	"888.9"	"894.2"	"1198.4"	"788.4"	"1101.1"	"784.0"	"1300.5"	"2040.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61224"	"Ras-related protein Rap-1b OS=Homo sapiens OX=9606 GN=RAP1B PE=1 SV=1"	"0.000"	""	"28"	"5"	"10"	"1"	"184"	"20.8"	"5.78"	"2332.67"	"19.39"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00071"	"5908"	"ENSG00000127314"	"RAP1B"	"B2R5Z2; B4DQI8; B4DW74; B4DW94; hsa:5908; P09526; P61224; Q502X3; Q5TZR4; Q6DCA1; Q6LES0"	"Neutrophil degranulation; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Signaling by BRAF and RAF1 fusions; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; Rap1 signalling; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; GRB2:SOS provides linkage to MAPK signaling for Integrins ; p130Cas linkage to MAPK signaling for integrins; MET activates RAP1 and RAC1"	"Integrin-mediated cell adhesion; Thyroid stimulating hormone (TSH) signaling pathway; Androgen receptor network in prostate cancer; Corticotropin-releasing hormone signaling pathway; Common pathways underlying drug addiction; Focal adhesion; Hepatocyte growth factor receptor signaling; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Ras signaling"	"25"	"0"	"38.3"	"11.0"	"47.9"	"29.8"	"45.5"	"40.8"	"37.5"	"55.4"	"28.6"	"56.9"	"64.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P32969"	"60S ribosomal protein L9 OS=Homo sapiens OX=9606 GN=RPL9 PE=1 SV=1"	"0.000"	""	"35"	"5"	"11"	"5"	"192"	"21.9"	"9.95"	"1939.98"	"19.39"	"4"	"5"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00347"	"6133"	"ENSG00000163682"	"RPL9; RPL9P7; RPL9P8; RPL9P9"	"hsa:6133; P32969"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"461.5"	"219.9"	"381.7"	"366.1"	"352.2"	"488.1"	"343.9"	"456.9"	"385.3"	"606.3"	"939.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P78347"	"General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2"	"0.000"	""	"9"	"8"	"12"	"8"	"998"	"112.3"	"6.39"	"2338.40"	"19.37"	"6"	"6"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02946"	"2969"	"ENSG00000263001"	"GTF2I"	"hsa:2969; O14743; O15359; O43546; O43588; O43589; P78347; Q75M85; Q75M86; Q75M87; Q75M88; Q86U51; Q9BSZ4"	""	"B cell receptor signaling pathway; 7q11.23 copy number variation syndrome; Genetic causes of porto-sinusoidal vascular disease"	"3"	"0"	"663.9"	"287.9"	"565.4"	"451.4"	"531.4"	"608.2"	"470.3"	"639.5"	"521.2"	"1038.9"	"2110.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55084"	"Trifunctional enzyme subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=HADHB PE=1 SV=3"	"0.000"	""	"18"	"9"	"16"	"8"	"474"	"51.3"	"9.41"	"2889.96"	"19.29"	"9"	"7"	"other metabolic processes;other biological processes"	"other membranes;mitochondrion;ER/Golgi"	"nucleic acid binding activity;other molecular function"	"Pf00108, Pf02803"	"3032"	"ENSG00000138029"	"HADHB"	"B2RB16; B4E2W0; hsa:3032; O14969; P55084; Q53TA6; Q96C77; Q9H3F5; Q9T2V8"	"Acyl chain remodeling of CL; mitochondrial fatty acid beta-oxidation of unsaturated fatty acids; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of myristoyl-CoA to lauroyl-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA; Beta oxidation of palmitoyl-CoA to myristoyl-CoA"	"Fatty acid beta-oxidation; Valproic acid pathway; Female steroid hormones in cardiomyocyte energy metabolism; Sudden infant death syndrome (SIDS) susceptibility pathways"	"12"	"1"	"1589.2"	"533.8"	"1139.5"	"984.8"	"1160.6"	"1384.5"	"1083.6"	"1432.4"	"1182.5"	"2372.5"	"4069.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49821"	"NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4"	"0.000"	""	"17"	"5"	"10"	"5"	"464"	"50.8"	"8.21"	"1795.62"	"19.26"	"5"	"5"	"other metabolic processes;transport"	"other membranes;cytosol;mitochondrion"	"transporter activity;other molecular function"	"Pf01512, Pf10531, Pf10589"	"4723"	"ENSG00000167792"	"NDUFV1"	"hsa:4723; O60924; O60940; P49821; Q16104; Q6IBR3; Q96BF8; Q96HS7"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"5"	"0"	"281.2"	"116.4"	"222.7"	"209.9"	"237.3"	"277.5"	"212.1"	"275.0"	"256.0"	"607.9"	"1275.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13123"	"Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3"	"0.000"	""	"11"	"6"	"12"	"6"	"557"	"65.6"	"6.64"	"2042.83"	"19.23"	"6"	"6"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07807, Pf07808"	"3550"	"ENSG00000113141"	"IK"	"hsa:3550; Q13123; Q6IPD8"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"1386.3"	"528.2"	"1073.0"	"944.8"	"1025.4"	"1184.0"	"844.0"	"1239.2"	"909.7"	"2490.2"	"5499.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62263"	"40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3"	"0.000"	""	"40"	"4"	"6"	"4"	"151"	"16.3"	"10.05"	"1018.61"	"19.20"	"2"	"4"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00411"	"6208"	"ENSG00000164587"	"RPS14"	"B2R5G5; D3DQG5; hsa:6208; P06366; P62263; Q5BJI0"	"Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; rRNA modification in the nucleus and cytosol; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Peptide chain elongation; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"20"	"0"	"353.1"	"136.2"	"280.0"	"204.1"	"269.4"	"317.3"	"241.9"	"328.7"	"257.4"	"444.6"	"775.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P84103"	"Serine/arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1"	"0.000"	""	"29"	"4"	"9"	"4"	"164"	"19.3"	"11.65"	"959.09"	"19.19"	"2"	"4"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6428"	"ENSG00000112081"	"SRSF3"	"B4E241; hsa:6428; O08831; P23152; P84103; Q5R3K0"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"mRNA processing"	"6"	"0"	"3207.4"	"904.7"	"1599.3"	"2224.9"	"1511.0"	"1546.2"	"1343.4"	"1835.3"	"1756.2"	"2755.9"	"3416.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13618"	"Cullin-3 OS=Homo sapiens OX=9606 GN=CUL3 PE=1 SV=2"	"0.000"	""	"11"	"6"	"9"	"6"	"768"	"88.9"	"8.48"	"1633.87"	"19.14"	"4"	"5"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00888, Pf10557"	"8452"	"ENSG00000036257"	"CUL3"	"A8K536; B8ZZC3; hsa:8452; O75415; Q13618; Q569L3; Q9UBI8; Q9UET7"	"Hedgehog 'on' state; Antigen processing: Ubiquitination & Proteasome degradation; Degradation of DVL; Regulation of RAS by GAPs; Neddylation; KEAP1-NFE2L2 pathway; Potential therapeutics for SARS; RHOBTB3 ATPase cycle; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle"	"Hedgehog signaling pathway; NRF2-ARE regulation; 22q11.2 copy number variation syndrome; Head and neck squamous cell carcinoma; 1p36 copy number variation syndrome"	"15"	"0"	"208.5"	"98.6"	"183.2"	"155.4"	"183.0"	"208.7"	"161.1"	"240.9"	"241.7"	"1052.0"	"2623.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42356"	"Phosphatidylinositol 4-kinase alpha OS=Homo sapiens OX=9606 GN=PI4KA PE=1 SV=4"	"0.000"	""	"3"	"5"	"8"	"5"	"2102"	"236.7"	"7.06"	"1048.08"	"19.13"	"3"	"5"	"other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"kinase activity;other molecular function"	"Pf00454, Pf00613, Pf19274"	"5297"	"ENSG00000241973"	"PI4KA"	"hsa:5297; P42356; Q7Z625; Q9UPG2"	"Synthesis of PIPs at the Golgi membrane; Synthesis of PIPs at the ER membrane"	"Ectoderm differentiation; 22q11.2 copy number variation syndrome"	"4"	"0"	"179.8"	"86.5"	"154.3"	"142.5"	"177.1"	"174.3"	"152.1"	"218.7"	"263.9"	"1190.5"	"2474.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16181"	"Septin-7 OS=Homo sapiens OX=9606 GN=SEPTIN7 PE=1 SV=2"	"0.000"	""	"15"	"5"	"7"	"4"	"437"	"50.6"	"8.63"	"1405.05"	"19.13"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00735"	"989"	"ENSG00000122545"	"SEPTIN7"	"hsa:989; Q16181; Q52M76; Q6NX50"	"MAPK6/MAPK4 signaling"	""	"1"	"1"	"260.0"	"99.3"	"205.8"	"199.5"	"256.1"	"324.5"	"279.1"	"389.1"	"314.1"	"920.8"	"2427.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60231"	"Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2"	"0.000"	""	"7"	"5"	"14"	"5"	"1041"	"119.2"	"6.80"	"2237.93"	"19.05"	"5"	"5"	"RNA metabolism OR transcription;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"8449"	"ENSG00000204560; ENSG00000206486; ENSG00000226171; ENSG00000231377; ENSG00000233049; ENSG00000233418; ENSG00000233561"	"DHX16"	"hsa:8449; O60231; O60322; Q5JP45; Q969X7; Q96QC1"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"0"	"243.3"	"87.7"	"199.0"	"177.0"	"211.1"	"231.1"	"174.4"	"266.4"	"229.4"	"421.0"	"887.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75369"	"Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2"	"0.000"	""	"3"	"5"	"9"	"5"	"2602"	"278.0"	"5.73"	"1398.59"	"19.04"	"4"	"5"	"cell organization and biogenesis;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00630"	"2317"	"ENSG00000136068"	"FLNB"	"B2ZZ83; B2ZZ84; B2ZZ85; C9JKE6; C9JMC4; hsa:2317; O75369; Q13706; Q59EC2; Q60FE7; Q6MZJ1; Q8WXS9; Q8WXT0; Q8WXT1; Q8WXT2; Q8WXT3; Q9NRB5; Q9NT26; Q9UEV9"	"ISG15 antiviral mechanism"	"Focal adhesion; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Ebola virus infection in host; NPHP1 deletion syndrome"	"6"	"0"	"170.5"	"76.0"	"158.0"	"112.0"	"140.7"	"151.4"	"129.1"	"149.4"	"158.2"	"273.9"	"451.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P60900"	"Proteasome subunit alpha type-6 OS=Homo sapiens OX=9606 GN=PSMA6 PE=1 SV=1"	"0.000"	""	"27"	"6"	"11"	"6"	"246"	"27.4"	"6.76"	"1829.54"	"19.01"	"5"	"6"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00227, Pf10584"	"5687"	"ENSG00000100902"	"PSMA6"	"B2R7J9; B4DQR4; B4DXJ9; hsa:5687; P34062; P60900; Q6IB60"	"Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"62"	"0"	"514.0"	"236.2"	"486.1"	"443.0"	"457.7"	"554.8"	"456.8"	"602.0"	"499.5"	"798.2"	"1124.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62995"	"Transformer-2 protein homolog beta OS=Homo sapiens OX=9606 GN=TRA2B PE=1 SV=1"	"0.000"	""	"16"	"5"	"11"	"5"	"288"	"33.6"	"11.25"	"1514.65"	"19.01"	"5"	"5"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6434"	"ENSG00000136527"	"TRA2B"	"B4DVK2; D3DNU3; hsa:6434; O15449; P62995; Q15815; Q64283"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle"	"mRNA processing"	"5"	"0"	"761.5"	"191.3"	"300.8"	"267.3"	"338.4"	"360.4"	"312.8"	"409.7"	"408.8"	"720.8"	"1353.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49458"	"Signal recognition particle 9 kDa protein OS=Homo sapiens OX=9606 GN=SRP9 PE=1 SV=2"	"0.000"	""	"53"	"6"	"13"	"6"	"86"	"10.1"	"7.97"	"2597.40"	"19.01"	"6"	"6"	"transport;other biological processes"	"other membranes;cytosol;ER/Golgi;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf05486"	"6726"	"ENSG00000143742"	"SRP9"	"A8K0N0; hsa:6726; P49458; Q6NVX0; Q8WTW0"	"SRP-dependent cotranslational protein targeting to membrane"	""	"1"	"0"	"473.1"	"181.9"	"408.7"	"341.6"	"388.9"	"476.4"	"387.5"	"634.2"	"942.8"	"7724.3"	"3044.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18859"	"ATP synthase-coupling factor 6, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PF PE=1 SV=1"	"0.000"	""	"36"	"2"	"7"	"2"	"108"	"12.6"	"9.52"	"1292.91"	"18.94"	"1"	"2"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf05511"	"522"	"ENSG00000154723"	"ATP5PF"	"hsa:522; J3KQ83; P18859"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"Electron transport chain: OXPHOS system in mitochondria; Oxidative phosphorylation"	"4"	"0"	"205.4"	"87.8"	"206.3"	"209.8"	"202.2"	"249.6"	"184.7"	"253.3"	"146.5"	"299.1"	"505.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15372"	"Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1"	"0.000"	""	"18"	"5"	"10"	"5"	"352"	"39.9"	"6.54"	"1949.51"	"18.89"	"5"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01398, Pf19445"	"8667"	"ENSG00000147677"	"EIF3H"	"hsa:8667; O15372"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"Translation factors; VEGFA-VEGFR2 signaling; Measles virus infection; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"10"	"0"	"852.1"	"329.7"	"752.1"	"667.4"	"736.2"	"877.4"	"578.6"	"790.8"	"528.5"	"990.6"	"1952.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96KR1"	"Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2"	"0.000"	""	"6"	"6"	"11"	"6"	"1074"	"116.9"	"9.04"	"1734.89"	"18.80"	"5"	"6"	""	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf07528, Pf12874"	"51663"	"ENSG00000056097"	"ZFR"	"B2RNR5; hsa:51663; Q05C08; Q3B7X5; Q6P5A3; Q86UA0; Q96KR1; Q9H6V4; Q9NTI1; Q9Y687"	""	"Exercise-induced circadian regulation"	"1"	"0"	"404.2"	"135.3"	"322.2"	"252.3"	"306.9"	"360.9"	"252.0"	"367.3"	"285.4"	"626.3"	"1122.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P33991"	"DNA replication licensing factor MCM4 OS=Homo sapiens OX=9606 GN=MCM4 PE=1 SV=5"	"0.000"	""	"6"	"6"	"10"	"6"	"863"	"96.5"	"6.74"	"1513.47"	"18.79"	"4"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855"	"4173"	"ENSG00000104738"	"MCM4"	"hsa:4173; P33991; Q8NEH1; Q99658"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"Cell cycle; Gastric cancer network 1; Retinoblastoma gene in cancer; Ciliary landscape; G1 to S cell cycle control; DNA replication"	"12"	"0"	"937.0"	"343.0"	"674.4"	"566.5"	"654.4"	"815.1"	"745.5"	"1057.9"	"839.4"	"1012.3"	"1748.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92598"	"Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1"	"0.000"	""	"8"	"6"	"10"	"5"	"858"	"96.8"	"5.39"	"1311.60"	"18.77"	"4"	"6"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00012"	"10808"	"ENSG00000120694"	"HSPH1"	"B4DYH1; hsa:10808; O95739; Q5TBM6; Q5TBM7; Q5TBM8; Q92598; Q9UPC4"	"Regulation of HSF1-mediated heat shock response; Scavenging by Class F Receptors"	""	"2"	"0"	"303.6"	"136.9"	"276.7"	"252.1"	"300.7"	"337.1"	"254.1"	"320.7"	"281.0"	"634.7"	"1062.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15144"	"Actin-related protein 2/3 complex subunit 2 OS=Homo sapiens OX=9606 GN=ARPC2 PE=1 SV=1"	"0.000"	""	"19"	"5"	"9"	"5"	"300"	"34.3"	"7.36"	"1078.90"	"18.72"	"2"	"5"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity"	"Pf04045"	"10109"	"ENSG00000163466"	"ARPC2"	"hsa:10109; O15144; Q92801; Q9P1D4"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"Pathogenic Escherichia coli infection"	"6"	"0"	"242.6"	"99.6"	"206.7"	"199.2"	"219.1"	"258.1"	"205.5"	"248.3"	"240.1"	"1486.9"	"4215.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14818"	"Proteasome subunit alpha type-7 OS=Homo sapiens OX=9606 GN=PSMA7 PE=1 SV=1"	"0.000"	""	"18"	"4"	"9"	"4"	"248"	"27.9"	"8.46"	"1544.18"	"18.70"	"3"	"4"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00227, Pf10584"	"5688"	"ENSG00000101182"	"PSMA7"	"B2R515; hsa:5688; O14818; Q5JXJ2; Q9BR53; Q9H4K5; Q9UEU8"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"62"	"0"	"472.5"	"205.4"	"415.5"	"381.9"	"416.5"	"471.0"	"425.5"	"535.5"	"497.5"	"744.1"	"1046.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P38919"	"Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4"	"0.000"	""	"13"	"5"	"11"	"4"	"411"	"46.8"	"6.73"	"2533.12"	"18.60"	"5"	"4"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"9775"	"ENSG00000141543"	"EIF4A3"	"hsa:9775; P38919; Q15033; Q6IBQ2; Q96A18"	"mRNA Splicing - Major Pathway; Regulation of expression of SLITs and ROBOs; Deadenylation of mRNA; ISG15 antiviral mechanism; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	"TAR syndrome"	"9"	"0"	"1376.3"	"419.6"	"737.2"	"615.8"	"752.3"	"853.2"	"664.1"	"895.6"	"834.3"	"1246.9"	"2409.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NX58"	"Cell growth-regulating nucleolar protein OS=Homo sapiens OX=9606 GN=LYAR PE=1 SV=2"	"0.000"	""	"14"	"4"	"9"	"4"	"379"	"43.6"	"9.54"	"1543.81"	"18.48"	"3"	"4"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"244.6"	"93.3"	"231.8"	"217.1"	"206.9"	"266.4"	"174.2"	"244.3"	"177.8"	"491.6"	"1124.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62495"	"Eukaryotic peptide chain release factor subunit 1 OS=Homo sapiens OX=9606 GN=ETF1 PE=1 SV=3"	"0.000"	""	"16"	"8"	"14"	"8"	"437"	"49.0"	"5.71"	"2767.11"	"18.47"	"8"	"6"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"enzyme regulator activity;translation activity;nucleic acid binding activity;other molecular function"	"Pf03463, Pf03464, Pf03465"	"2107"	"ENSG00000120705"	"ETF1"	"B2R6B4; D3DQC1; hsa:2107; P46055; P62495; Q5M7Z7; Q96CG1"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Translation factors"	"5"	"0"	"579.3"	"286.0"	"555.3"	"479.5"	"524.3"	"675.5"	"470.5"	"615.7"	"510.6"	"923.5"	"1609.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96FN4"	"Copine-2 OS=Homo sapiens OX=9606 GN=CPNE2 PE=1 SV=3"	"0.000"	""	"9"	"4"	"10"	"3"	"548"	"61.2"	"6.07"	"1921.64"	"18.42"	"4"	"4"	"other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00168, Pf07002"	"221184"	"ENSG00000140848"	"CPNE2"	"hsa:221184; Q68D19; Q719H8; Q86XP9; Q96FN4"	""	""	"0"	"0"	"178.5"	"68.4"	"159.8"	"124.0"	"121.5"	"171.7"	"152.2"	"208.3"	"173.1"	"333.7"	"909.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3A5"	"Ribosome maturation protein SBDS OS=Homo sapiens OX=9606 GN=SBDS PE=1 SV=4"	"0.000"	""	"21"	"6"	"7"	"6"	"250"	"28.7"	"8.75"	"418.57"	"18.35"	"1"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;translation activity;nucleic acid binding activity"	"Pf01172, Pf09377, Pf20268"	"51119"	"ENSG00000126524"	"SBDS"	"A8K0P4; hsa:51119; Q96FX0; Q9NV53; Q9Y3A5"	""	"Genetic causes of porto-sinusoidal vascular disease"	"1"	"0"	"267.8"	"120.7"	"234.3"	"189.1"	"208.5"	"267.9"	"186.0"	"329.1"	"384.3"	"2513.3"	"5186.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14257"	"Reticulocalbin-2 OS=Homo sapiens OX=9606 GN=RCN2 PE=1 SV=1"	"0.000"	""	"18"	"4"	"7"	"4"	"317"	"36.9"	"4.40"	"1874.38"	"18.31"	"3"	"4"	""	"ER/Golgi;nucleus"	"other molecular function"	"Pf13202"	"5955"	"ENSG00000117906"	"RCN2"	"A8MTG6; F8WCY5; hsa:5955; Q14257; Q53XN8"	""	""	"0"	"0"	"243.5"	"106.8"	"303.5"	"239.8"	"259.0"	"316.4"	"212.4"	"285.7"	"197.5"	"404.7"	"510.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BWS9"	"Chitinase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHID1 PE=1 SV=1"	"0.000"	""	"11"	"5"	"10"	"5"	"393"	"44.9"	"8.63"	"1729.47"	"18.28"	"4"	"4"	"other metabolic processes;stress response;other biological processes"	"non-structural extracellular;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00704"	"66005"	"ENSG00000177830"	"CHID1"	"B3KWB0; hsa:66005; Q8NBM9; Q96CZ3; Q96S93; Q96SK0; Q9BWS9; Q9BY52"	"Platelet degranulation"	""	"1"	"0"	"701.3"	"270.4"	"722.5"	"628.4"	"667.3"	"825.9"	"538.2"	"872.6"	"783.3"	"4708.6"	"6991.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P83916"	"Chromobox protein homolog 1 OS=Homo sapiens OX=9606 GN=CBX1 PE=1 SV=1"	"0.000"	""	"29"	"4"	"11"	"3"	"185"	"21.4"	"4.93"	"2931.44"	"18.21"	"4"	"3"	"cell organization and biogenesis;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00385, Pf01393"	"10951"	"ENSG00000108468"	"CBX1"	"hsa:10951; P23197; P83916"	"HCMV Early Events"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"2"	"0"	"298.9"	"133.8"	"263.9"	"250.3"	"282.1"	"339.1"	"276.4"	"354.1"	"277.3"	"445.8"	"680.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25788"	"Proteasome subunit alpha type-3 OS=Homo sapiens OX=9606 GN=PSMA3 PE=1 SV=2"	"0.000"	""	"20"	"5"	"10"	"5"	"255"	"28.4"	"5.33"	"1644.54"	"18.21"	"3"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00227, Pf10584"	"5684"	"ENSG00000100567"	"PSMA3"	"B2RCK6; hsa:5684; P25788; Q86U83; Q8N1D8; Q9BS70"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Cross-presentation of soluble exogenous antigens (endosomes); Regulation of ornithine decarboxylase (ODC); Somitogenesis"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"62"	"0"	"872.7"	"383.1"	"805.8"	"815.2"	"816.3"	"947.5"	"767.4"	"994.0"	"764.0"	"1464.6"	"2373.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H2U1"	"ATP-dependent DNA/RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2"	"0.000"	""	"8"	"5"	"9"	"5"	"1008"	"114.7"	"7.68"	"1142.39"	"18.19"	"4"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"170506"	"ENSG00000174953"	"DHX36"	"B2RB00; hsa:170506; Q70JU3; Q8IYE5; Q9H2U1; Q9P240"	"DEx/H-box helicases activate type I IFN and inflammatory cytokines production"	"VEGFA-VEGFR2 signaling"	"2"	"0"	"196.6"	"99.6"	"172.6"	"164.2"	"166.7"	"189.8"	"153.6"	"188.4"	"174.1"	"558.9"	"1239.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96A72"	"Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1"	"0.000"	""	"30"	"4"	"10"	"4"	"148"	"17.3"	"6.39"	"2057.94"	"18.16"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf02792"	"55110"	"ENSG00000111196"	"MAGOHB"	"hsa:55110; Q96A72"	"Regulation of expression of SLITs and ROBOs; mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	""	"6"	"0"	"364.0"	"94.8"	"206.3"	"167.9"	"239.9"	"241.6"	"200.6"	"262.4"	"203.0"	"422.3"	"987.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63167"	"Dynein light chain 1, cytoplasmic OS=Homo sapiens OX=9606 GN=DYNLL1 PE=1 SV=1"	"0.000"	""	"57"	"4"	"7"	"2"	"89"	"10.4"	"7.40"	"534.20"	"18.11"	"2"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01221"	"8655"	"ENSG00000088986"	"DYNLL1"	"hsa:8655; P63167; Q15701"	"MHC class II antigen presentation; COPI-mediated anterograde transport; HCMV Early Events; Neutrophil degranulation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-independent Golgi-to-ER retrograde traffic; Intraflagellar transport; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Recruitment of NuMA to mitotic centrosomes; RHO GTPases Activate Formins; Aggrephagy; EML4 and NUDC in mitotic spindle formation; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Macroautophagy; Activation of BIM and translocation to mitochondria"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; Genes related to primary cilium development (based on CRISPR); 3q29 copy number variation syndrome"	"27"	"2"	"577.6"	"303.5"	"616.7"	"587.7"	"541.7"	"748.2"	"530.0"	"755.6"	"537.6"	"761.4"	"1320.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P16152"	"Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3"	"0.000"	""	"20"	"5"	"11"	"5"	"277"	"30.4"	"8.32"	"1763.81"	"18.02"	"4"	"5"	"other metabolic processes;other biological processes"	"cytosol"	"other molecular function"	"Pf00106"	"873"	"ENSG00000159228"	"CBR1"	"B2RBZ7; B4DFK7; hsa:873; P16152; Q3LHW8"	"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)"	"Nuclear receptors meta-pathway; NRF2 pathway; Prostaglandin synthesis and regulation"	"4"	"0"	"457.9"	"223.6"	"406.7"	"399.5"	"346.6"	"489.9"	"365.9"	"493.3"	"383.2"	"887.7"	"2128.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15370"	"Elongin-B OS=Homo sapiens OX=9606 GN=ELOB PE=1 SV=1"	"0.000"	""	"52"	"5"	"9"	"5"	"118"	"13.1"	"4.88"	"1632.14"	"17.99"	"4"	"5"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00240"	"6923"	"ENSG00000103363"	"ELOB"	"B7WPD3; hsa:6923; Q15370"	"Regulation of expression of SLITs and ROBOs; Antigen processing: Ubiquitination & Proteasome degradation; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Vif-mediated degradation of APOBEC3G; Neddylation; Inactivation of CSF3 (G-CSF) signaling; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes"	"Dual hijack model of Vif in HIV infection; Type 2 papillary renal cell carcinoma; Hijack of ubiquitination by SARS-CoV-2; Modulators of TCR signaling and T cell activation"	"21"	"0"	"679.5"	"317.5"	"752.8"	"760.4"	"785.0"	"959.4"	"687.2"	"795.7"	"503.8"	"1344.4"	"2857.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q05048"	"Cleavage stimulation factor subunit 1 OS=Homo sapiens OX=9606 GN=CSTF1 PE=1 SV=1"	"0.000"	""	"12"	"5"	"10"	"5"	"431"	"48.3"	"6.58"	"1761.87"	"17.92"	"5"	"5"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf00400, Pf16699"	"1477"	"ENSG00000101138"	"CSTF1"	"hsa:1477; Q05048; Q5QPD8"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"mRNA processing"	"5"	"0"	"657.5"	"250.7"	"678.5"	"636.3"	"612.7"	"828.4"	"595.1"	"739.5"	"540.5"	"1315.5"	"2501.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9C0J8"	"pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2"	"0.000"	""	"4"	"4"	"10"	"4"	"1336"	"145.8"	"9.17"	"1985.18"	"17.90"	"4"	"4"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	""	"Pf00400"	"55339"	"ENSG00000136709"	"WDR33"	"hsa:55339; Q05DP8; Q53FG9; Q587J1; Q69YF7; Q6NUQ0; Q9C0J8; Q9NUL1"	"Transport of Mature mRNA Derived from an Intronless Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	""	"5"	"0"	"279.5"	"102.3"	"200.2"	"163.4"	"191.9"	"196.7"	"152.1"	"227.4"	"198.4"	"364.4"	"595.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P28066"	"Proteasome subunit alpha type-5 OS=Homo sapiens OX=9606 GN=PSMA5 PE=1 SV=3"	"0.000"	""	"22"	"3"	"7"	"3"	"241"	"26.4"	"4.79"	"1368.88"	"17.89"	"2"	"3"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf00227, Pf10584"	"5686"	"ENSG00000143106"	"PSMA5"	"B2R8F6; B4E2V4; hsa:5686; P28066; Q3T1C1; Q6IBF7"	"UCH proteinases; ER-Phagosome pathway; Ub-specific processing proteases; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"63"	"0"	"156.2"	"47.6"	"155.1"	"164.9"	"153.7"	"186.0"	"143.2"	"187.2"	"140.2"	"239.1"	"334.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96FJ2"	"Dynein light chain 2, cytoplasmic OS=Homo sapiens OX=9606 GN=DYNLL2 PE=1 SV=1"	"0.000"	""	"57"	"4"	"8"	"2"	"89"	"10.3"	"7.37"	"846.93"	"17.83"	"2"	"4"	"other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf01221"	"140735"	"ENSG00000264364"	"DYNLL2"	"B2R5B4; hsa:140735; Q96FJ2"	"Separation of Sister Chromatids; MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; RHO GTPases Activate Formins; Intraflagellar transport; Resolution of Sister Chromatid Cohesion; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; HCMV Early Events; Aggrephagy; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Macroautophagy; Activation of BMF and translocation to mitochondria"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; 3q29 copy number variation syndrome"	"18"	"0"	"753.0"	"362.5"	"773.8"	"838.2"	"750.3"	"943.1"	"702.8"	"940.4"	"577.4"	"966.3"	"1573.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IY18"	"Structural maintenance of chromosomes protein 5 OS=Homo sapiens OX=9606 GN=SMC5 PE=1 SV=2"	"0.000"	""	"6"	"6"	"12"	"6"	"1101"	"128.7"	"8.38"	"1788.06"	"17.69"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463"	"23137"	"ENSG00000198887"	"SMC5"	"A6NM81; hsa:23137; O60335; Q05D92; Q5VZ60; Q8IY18; Q96SB9"	"SUMOylation of DNA damage response and repair proteins"	""	"1"	"0"	"132.9"	"67.9"	"117.9"	"98.6"	"115.3"	"130.3"	"93.3"	"141.2"	"123.4"	"278.4"	"747.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49207"	"60S ribosomal protein L34 OS=Homo sapiens OX=9606 GN=RPL34 PE=1 SV=3"	"0.000"	""	"22"	"4"	"11"	"4"	"117"	"13.3"	"11.47"	"1689.08"	"17.68"	"4"	"4"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01199"	"6164"	"ENSG00000109475"	"RPL34"	"hsa:6164; P49207; Q6FG66; Q9BUZ2"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"1136.4"	"445.0"	"977.3"	"849.0"	"918.0"	"1076.6"	"848.8"	"1087.2"	"816.7"	"1373.2"	"1691.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P17480"	"Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1"	"0.000"	""	"9"	"5"	"10"	"5"	"764"	"89.4"	"5.81"	"2281.21"	"17.63"	"5"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00505, Pf09011, Pf14887"	"7343"	"ENSG00000108312"	"UBTF"	"A8K6R8; hsa:7343; P17480"	"NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; RNA Polymerase I Promoter Opening"	"Ectoderm differentiation"	"6"	"0"	"95.4"	"42.9"	"77.8"	"68.7"	"69.9"	"77.7"	"74.3"	"121.6"	"171.2"	"681.4"	"856.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60645"	"Exocyst complex component 3 OS=Homo sapiens OX=9606 GN=EXOC3 PE=1 SV=3"	"0.000"	""	"7"	"4"	"8"	"4"	"745"	"85.5"	"6.29"	"1143.74"	"17.60"	"2"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf06046"	"11336"	"ENSG00000180104"	"EXOC3"	"hsa:11336; O60645; Q6P2E8; Q8TEN6; Q8WUW0; Q96DI4"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"Ciliary landscape"	"4"	"0"	"82.3"	"33.2"	"66.9"	"62.5"	"73.0"	"82.7"	"81.8"	"248.2"	"580.9"	"1980.4"	"2960.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P36954"	"DNA-directed RNA polymerase II subunit RPB9 OS=Homo sapiens OX=9606 GN=POLR2I PE=1 SV=1"	"0.000"	""	"38"	"4"	"6"	"4"	"125"	"14.5"	"5.14"	"419.77"	"17.56"	"1"	"4"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01096, Pf02150"	"5438"	"ENSG00000105258"	"POLR2I"	"B2R5J2; hsa:5438; P36954; Q6NW05"	"mRNA Splicing - Major Pathway; Transcriptional regulation by small RNAs; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Inhibition of DNA recombination at telomere; Processing of Capped Intron-Containing Pre-mRNA; Viral Messenger RNA Synthesis; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Signaling by FGFR2 IIIa TM"	"Pyrimidine metabolism; Eukaryotic transcription initiation"	"43"	"0"	"505.7"	"227.8"	"419.4"	"405.2"	"391.1"	"456.0"	"357.8"	"525.6"	"439.1"	"692.5"	"996.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62277"	"40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2"	"0.000"	""	"50"	"8"	"13"	"8"	"151"	"17.2"	"10.54"	"2391.14"	"17.53"	"7"	"6"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00312, Pf08069"	"6207"	"ENSG00000110700"	"RPS13"	"B2R549; hsa:6207; P19116; P62277; Q02546; Q29200; Q498Y0"	"Major pathway of rRNA processing in the nucleolus and cytosol; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Selenocysteine synthesis; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"1680.8"	"739.1"	"1456.2"	"1197.3"	"1397.1"	"1762.0"	"1277.2"	"1642.1"	"1143.5"	"1794.2"	"2899.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VUJ6"	"Leucine-rich repeat and calponin homology domain-containing protein 2 OS=Homo sapiens OX=9606 GN=LRCH2 PE=1 SV=2"	"0.000"	""	"8"	"4"	"8"	"4"	"765"	"84.5"	"6.55"	"1789.18"	"17.49"	"4"	"4"	""	""	""	"Pf00307, Pf13855"	"57631"	"ENSG00000130224"	"LRCH2"	"F5H2T1; hsa:57631; Q08AD5; Q5VUJ6; Q9HA88; Q9P233"	""	""	"0"	"0"	"147.2"	"66.9"	"152.9"	"139.5"	"136.8"	"174.1"	"146.9"	"223.3"	"172.0"	"606.4"	"1504.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49757"	"Protein numb homolog OS=Homo sapiens OX=9606 GN=NUMB PE=1 SV=2"	"0.000"	""	"8"	"4"	"9"	"4"	"651"	"70.8"	"8.51"	"1553.94"	"17.46"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00640, Pf06311"	"8650"	"ENSG00000133961"	"NUMB"	"B1P2N5; B1P2N6; B1P2N7; B1P2N8; B1P2N9; B4E2B1; hsa:8650; P49757; Q6NUQ7; Q86SY1; Q8WW73; Q9UBG1; Q9UEQ4; Q9UKE8; Q9UKE9; Q9UKF0; Q9UQJ4"	"Recycling pathway of L1; Degradation of GLI1 by the proteasome; Hedgehog 'on' state; Activated NOTCH1 Transmits Signal to the Nucleus"	"Notch signaling; VEGFA-VEGFR2 signaling; Head and neck squamous cell carcinoma; Neurogenesis regulation in the olfactory epithelium; TROP2 regulatory signaling; Notch signaling pathway"	"10"	"0"	"126.6"	"56.7"	"106.6"	"95.5"	"106.0"	"139.1"	"181.8"	"406.5"	"608.4"	"1164.3"	"1498.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99590"	"Protein SCAF11 OS=Homo sapiens OX=9606 GN=SCAF11 PE=1 SV=2"	"0.000"	""	"3"	"5"	"11"	"5"	"1463"	"164.6"	"8.41"	"1930.84"	"17.37"	"5"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	""	"9169"	"ENSG00000139218"	"SCAF11"	"A6NEU9; A6NLW5; hsa:9169; Q8IW59; Q99590"	""	"Apoptosis"	"1"	"0"	"623.6"	"276.7"	"605.3"	"525.3"	"567.2"	"662.3"	"470.1"	"676.6"	"548.1"	"2325.0"	"4520.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96QC0"	"Serine/threonine-protein phosphatase 1 regulatory subunit 10 OS=Homo sapiens OX=9606 GN=PPP1R10 PE=1 SV=1"	"0.000"	""	"6"	"5"	"10"	"5"	"940"	"99.0"	"9.17"	"2028.12"	"17.35"	"5"	"5"	"transport;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00642, Pf08711"	"5514"	"ENSG00000204569; ENSG00000206489; ENSG00000227804; ENSG00000230995; ENSG00000231737; ENSG00000235291; ENSG00000238104"	"PPP1R10"	"hsa:5514; O00405; Q96QC0"	""	""	"0"	"0"	"623.1"	"211.5"	"536.7"	"433.4"	"536.4"	"580.8"	"390.0"	"579.2"	"379.0"	"949.7"	"2509.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86UP2"	"Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1"	"0.000"	""	"4"	"5"	"9"	"5"	"1357"	"156.2"	"5.64"	"1353.58"	"17.34"	"4"	"5"	"transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi"	"cytoskeletal activity"	"Pf05104"	"3895"	"ENSG00000126777"	"KTN1"	"B4DZ88; hsa:3895; Q13999; Q14707; Q15387; Q17RZ5; Q5GGW3; Q86UP2; Q86W57"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RND2 GTPase cycle; RND3 GTPase cycle; RHOG GTPase cycle; RHO GTPases activate KTN1"	"Glucocorticoid receptor pathway; Nuclear receptors meta-pathway"	"11"	"0"	"540.7"	"169.5"	"334.5"	"264.9"	"325.3"	"347.9"	"277.7"	"392.7"	"336.1"	"747.9"	"2014.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NQG5"	"Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1"	"0.000"	""	"21"	"6"	"12"	"4"	"326"	"36.9"	"5.97"	"2709.93"	"17.34"	"6"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf04818, Pf16566"	"58490"	"ENSG00000101413"	"RPRD1B"	"hsa:58490; Q1WDE7; Q6PKF4; Q9NQG5"	"RNA polymerase II transcribes snRNA genes"	"Modulators of TCR signaling and T cell activation"	"2"	"0"	"360.6"	"135.2"	"279.9"	"239.4"	"271.8"	"351.5"	"275.2"	"347.5"	"278.9"	"482.5"	"754.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25685"	"DnaJ homolog subfamily B member 1 OS=Homo sapiens OX=9606 GN=DNAJB1 PE=1 SV=4"	"0.000"	""	"21"	"6"	"10"	"5"	"340"	"38.0"	"8.63"	"1632.93"	"17.34"	"5"	"4"	"protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00226, Pf01556"	"3337"	"ENSG00000132002"	"DNAJB1"	"B4DX52; hsa:3337; P25685"	"MAPK6/MAPK4 signaling; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Regulation of HSF1-mediated heat shock response; Attenuation phase"	"Nuclear receptors meta-pathway; NRF2 pathway"	"7"	"1"	"581.7"	"257.8"	"586.3"	"463.4"	"558.7"	"586.6"	"435.3"	"608.8"	"461.9"	"989.8"	"1460.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6PKG0"	"La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2"	"0.000"	""	"7"	"5"	"10"	"5"	"1096"	"123.4"	"8.82"	"1894.64"	"17.34"	"5"	"5"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf05383"	"23367"	"ENSG00000155506"	"LARP1"	"hsa:23367; O94836; Q6PKG0; Q8N4M2; Q8NB73; Q9UFD7"	"SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins; SARS-CoV-2 innate immunity evasion and cell-specific immune response; Network map of SARS-CoV-2 signaling pathway"	"4"	"0"	"412.2"	"198.4"	"337.9"	"298.9"	"336.3"	"380.9"	"282.1"	"386.1"	"298.1"	"518.2"	"827.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99832"	"T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2"	"0.000"	""	"12"	"5"	"11"	"5"	"543"	"59.3"	"7.65"	"1600.49"	"17.32"	"4"	"5"	"protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00118"	"10574"	"ENSG00000135624"	"CCT7"	"A8K7E6; A8MWI8; B7WNW9; B7Z4T9; B7Z4Z7; hsa:10574; O14871; Q6FI26; Q99832"	"RHOBTB1 GTPase cycle; Formation of tubulin folding intermediates by CCT/TriC; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; RHOBTB2 GTPase cycle; Folding of actin by CCT/TriC"	"VEGFA-VEGFR2 signaling; 16p11.2 proximal deletion syndrome"	"9"	"0"	"731.2"	"246.4"	"602.0"	"493.0"	"622.3"	"639.3"	"470.2"	"604.5"	"450.7"	"916.1"	"1822.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P17980"	"26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3"	"0.000"	""	"12"	"4"	"10"	"4"	"439"	"49.2"	"5.24"	"1951.65"	"17.32"	"4"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf16450, Pf17862"	"5702"	"ENSG00000165916"	"PSMC3"	"B2R8V1; hsa:5702; P17980; Q3B757; Q3B865; Q53HU5; Q6GPG8; Q6IBS1; Q96HD3"	"Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Neutrophil degranulation; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; ABC-family proteins mediated transport; Defective CFTR causes cystic fibrosis; UCH proteinases; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; MAPK6/MAPK4 signaling; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"64"	"0"	"279.0"	"127.3"	"256.5"	"200.9"	"243.6"	"273.0"	"188.4"	"256.8"	"199.4"	"370.4"	"646.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13310"	"Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1"	"0.000"	""	"9"	"6"	"12"	"3"	"644"	"70.7"	"9.26"	"1858.17"	"17.27"	"5"	"5"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf00658"	"8761"	"ENSG00000090621"	"PABPC4"	"B1ANQ8; hsa:8761; Q13310; Q4VC03; Q6P0N3"	""	""	"0"	"0"	"576.4"	"246.8"	"498.7"	"411.6"	"464.9"	"536.9"	"391.1"	"504.5"	"389.2"	"836.2"	"1300.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46087"	"Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NOP2 PE=1 SV=2"	"0.000"	""	"7"	"5"	"10"	"5"	"812"	"89.2"	"9.23"	"1654.43"	"17.21"	"5"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf01189, Pf08062, Pf17125"	"4839"	"ENSG00000111641"	"NOP2"	"A1A4Z3; B3KPD6; hsa:4839; P46087; Q05BA7; Q0P5S5; Q3KQS4; Q58F30"	"rRNA modification in the nucleus and cytosol; TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"	"Imatinib and chronic myeloid leukemia"	"3"	"0"	"539.2"	"283.2"	"556.0"	"545.6"	"568.8"	"601.9"	"460.4"	"599.5"	"474.8"	"1018.8"	"1837.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15514"	"DNA-directed RNA polymerase II subunit RPB4 OS=Homo sapiens OX=9606 GN=POLR2D PE=1 SV=1"	"0.000"	""	"45"	"4"	"6"	"4"	"142"	"16.3"	"4.79"	"752.17"	"17.20"	"2"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf03874"	"5433"	"ENSG00000144231"	"POLR2D"	"hsa:5433; O15514; Q52LT4"	"Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; mRNA Splicing - Major Pathway; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"Pyrimidine metabolism"	"42"	"0"	"417.0"	"175.2"	"383.2"	"365.8"	"392.5"	"494.2"	"365.4"	"449.0"	"328.8"	"608.3"	"965.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BY77"	"Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2"	"0.000"	""	"14"	"4"	"8"	"4"	"421"	"46.1"	"9.99"	"1647.56"	"17.20"	"4"	"4"	"other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"84271"	"ENSG00000100227"	"POLDIP3"	"A8K6F8; A8K6V9; hsa:84271; Q009A7; Q5H972; Q6PGN6; Q7Z6Z0; Q9BY77; Q9NSP5; Q9NSP6"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript"	""	"3"	"0"	"254.0"	"85.7"	"186.4"	"145.2"	"219.7"	"220.6"	"159.6"	"213.2"	"167.9"	"326.0"	"537.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46776"	"60S ribosomal protein L27a OS=Homo sapiens OX=9606 GN=RPL27A PE=1 SV=2"	"0.000"	""	"28"	"4"	"10"	"4"	"148"	"16.6"	"11.00"	"1969.12"	"17.18"	"4"	"4"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;other cell component"	"other molecular function"	"Pf00828"	"6157"	"ENSG00000166441"	"RPL27A"	"B2R4B3; hsa:6157; P46776"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"803.2"	"358.1"	"697.3"	"596.6"	"690.5"	"768.1"	"580.5"	"738.3"	"559.7"	"944.7"	"1334.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HCC0"	"Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC2 PE=1 SV=1"	"0.000"	""	"13"	"7"	"12"	"7"	"563"	"61.3"	"7.68"	"2193.88"	"17.15"	"6"	"6"	"other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf01039"	"64087"	"ENSG00000131844"	"MCCC2"	"A6NIY9; hsa:64087; Q96C27; Q9HCC0; Q9Y4L7"	"Biotin transport and metabolism; Branched-chain amino acid catabolism; Defective HLCS causes multiple carboxylase deficiency"	""	"3"	"0"	"1263.3"	"724.3"	"1325.5"	"1174.7"	"1318.7"	"1445.2"	"1120.0"	"1369.0"	"990.5"	"1621.3"	"2042.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H0C8"	"Integrin-linked kinase-associated serine/threonine phosphatase 2C OS=Homo sapiens OX=9606 GN=ILKAP PE=1 SV=1"	"0.000"	""	"10"	"4"	"10"	"4"	"392"	"42.9"	"7.09"	"1726.84"	"17.11"	"4"	"4"	"protein metabolism;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00481"	"80895"	"ENSG00000132323"	"ILKAP"	"B3KM39; hsa:80895; Q9H0C8"	""	"2q37 copy number variation syndrome"	"1"	"0"	"471.5"	"210.8"	"376.0"	"317.1"	"364.4"	"438.8"	"304.1"	"391.6"	"340.0"	"761.5"	"2010.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13442"	"28 kDa heat- and acid-stable phosphoprotein OS=Homo sapiens OX=9606 GN=PDAP1 PE=1 SV=1"	"0.000"	""	"30"	"5"	"11"	"5"	"181"	"20.6"	"8.87"	"2478.58"	"17.06"	"5"	"4"	"signal transduction"	"non-structural extracellular;plasma membrane;other membranes;cytosol;other cell component"	""	"Pf10252"	"11333"	"ENSG00000106244"	"PDAP1"	"D6W5S5; hsa:11333; Q13442; Q92906"	"Neutrophil degranulation"	""	"1"	"0"	"819.8"	"312.4"	"822.8"	"825.2"	"802.3"	"1031.9"	"724.8"	"1174.5"	"721.5"	"1565.0"	"1713.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96CX2"	"BTB/POZ domain-containing protein KCTD12 OS=Homo sapiens OX=9606 GN=KCTD12 PE=1 SV=1"	"0.000"	""	"19"	"5"	"9"	"5"	"325"	"35.7"	"5.64"	"1400.91"	"17.05"	"4"	"5"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf02214"	"115207"	"ENSG00000178695"	"KCTD12"	"hsa:115207; Q96CX2"	""	""	"0"	"0"	"125.6"	"46.5"	"101.0"	"95.2"	"108.2"	"113.6"	"96.7"	"131.4"	"125.9"	"368.6"	"1568.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49750"	"YLP motif-containing protein 1 OS=Homo sapiens OX=9606 GN=YLPM1 PE=1 SV=4"	"0.000"	""	"3"	"6"	"11"	"6"	"2146"	"241.5"	"6.55"	"1505.00"	"17.04"	"5"	"6"	"other biological processes"	"cytosol;nucleus"	""	"Pf13671"	"56252"	"ENSG00000119596"	"YLPM1"	"hsa:56252; P49750; P49752; Q96I64; Q9P1V7"	""	""	"0"	"0"	"960.2"	"378.7"	"701.4"	"564.1"	"679.3"	"687.0"	"552.6"	"797.1"	"671.6"	"1453.2"	"1611.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BRG1"	"Vacuolar protein-sorting-associated protein 25 OS=Homo sapiens OX=9606 GN=VPS25 PE=1 SV=1"	"0.000"	""	"43"	"7"	"12"	"7"	"176"	"20.7"	"6.34"	"3385.45"	"16.94"	"7"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf05871"	"84313"	"ENSG00000131475"	"VPS25"	"B2R581; hsa:84313; Q9BRG1"	"HCMV Late Events; Endosomal Sorting Complex Required For Transport (ESCRT)"	""	"2"	"0"	"107.8"	"47.6"	"103.7"	"96.3"	"119.2"	"133.7"	"120.3"	"235.6"	"326.2"	"1273.6"	"2511.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19404"	"NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV2 PE=1 SV=2"	"0.000"	""	"24"	"5"	"8"	"5"	"249"	"27.4"	"8.06"	"958.71"	"16.94"	"3"	"5"	"other metabolic processes;transport;developmental processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf01257"	"4729"	"ENSG00000178127"	"NDUFV2"	"hsa:4729; P19404; Q9BV41"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"5"	"0"	"441.1"	"153.4"	"333.1"	"269.4"	"342.9"	"363.5"	"332.7"	"402.8"	"344.2"	"717.4"	"1484.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22392"	"Nucleoside diphosphate kinase B OS=Homo sapiens OX=9606 GN=NME2 PE=1 SV=1"	"0.000"	""	"36"	"5"	"10"	"2"	"152"	"17.3"	"8.41"	"1577.97"	"16.93"	"5"	"5"	"cell adhesion;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00334"	"4831; 654364"	"ENSG00000243678"	"NME2"	"A8MWA3; hsa:4831; hsa:654364; P22392; Q1WM23; Q6LCT6"	"Neutrophil degranulation; Interconversion of nucleotide di- and triphosphates; Azathioprine ADME; Ribavirin ADME"	"Pyrimidine metabolism"	"5"	"3"	"762.9"	"227.5"	"474.7"	"325.5"	"500.8"	"485.3"	"476.4"	"544.1"	"670.8"	"898.2"	"1516.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12904"	"Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1 PE=1 SV=2"	"0.000"	""	"21"	"5"	"6"	"5"	"312"	"34.3"	"8.43"	"742.19"	"16.90"	"2"	"4"	"cell-cell signaling;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf01588"	"9255"	"ENSG00000164022"	"AIMP1"	"B3KTR2; B4E1S7; hsa:9255; Q12904; Q6FG28; Q96CQ9"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"Ciliary landscape"	"3"	"0"	"384.8"	"157.9"	"328.9"	"264.0"	"291.4"	"370.4"	"299.7"	"521.4"	"462.9"	"1840.2"	"4280.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P41567"	"Eukaryotic translation initiation factor 1 OS=Homo sapiens OX=9606 GN=EIF1 PE=1 SV=1"	"0.000"	""	"45"	"3"	"6"	"1"	"113"	"12.7"	"7.44"	"765.23"	"16.83"	"2"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf01253"	"10209"	"ENSG00000173812"	"EIF1"	"hsa:10209; P41567; Q9UNQ9"	""	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"2"	"0"	"44.3"	"9.6"	"33.2"	"28.4"	"36.2"	"44.4"	"29.2"	"54.5"	"78.7"	"192.4"	"936.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96NC0"	"Zinc finger matrin-type protein 2 OS=Homo sapiens OX=9606 GN=ZMAT2 PE=1 SV=1"	"0.000"	""	"29"	"6"	"13"	"6"	"199"	"23.6"	"9.01"	"2034.29"	"16.75"	"5"	"5"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf12171"	"153527"	"ENSG00000146007"	"ZMAT2"	"hsa:153527; Q96NC0"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"1788.5"	"644.7"	"1398.3"	"1157.9"	"1297.0"	"1549.5"	"1072.8"	"1742.7"	"1284.3"	"3677.4"	"6775.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50991"	"T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4"	"0.000"	""	"12"	"4"	"9"	"4"	"539"	"57.9"	"7.83"	"1626.40"	"16.74"	"3"	"4"	"protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00118"	"10575"	"ENSG00000115484"	"CCT4"	"B2R6I3; B7Z8B1; F5H5W3; hsa:10575; O14870; P50991; Q53QP9; Q96C51"	"Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"16p11.2 proximal deletion syndrome"	"7"	"0"	"778.6"	"328.5"	"667.8"	"575.3"	"656.2"	"720.0"	"560.3"	"642.9"	"494.7"	"926.7"	"2077.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P28340"	"DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2"	"0.000"	""	"6"	"5"	"10"	"5"	"1107"	"123.6"	"7.03"	"1821.79"	"16.70"	"5"	"5"	"DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00136, Pf03104, Pf14260"	"5424"	"ENSG00000062822"	"POLD1"	"hsa:5424; P28340; Q8NER3; Q96H98"	"Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Cytosolic iron-sulfur cluster assembly; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Polymerase switching on the C-strand of the telomere; Polymerase switching; Removal of the Flap Intermediate; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"Homologous recombination; Pyrimidine metabolism; DNA replication; Base excision repair; Nucleotide excision repair; DNA repair pathways, full network; Progeria-associated lipodystrophy; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"27"	"0"	"192.6"	"82.0"	"173.0"	"152.0"	"168.8"	"186.6"	"144.0"	"202.1"	"198.3"	"468.0"	"960.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92747"	"Actin-related protein 2/3 complex subunit 1A OS=Homo sapiens OX=9606 GN=ARPC1A PE=2 SV=2"	"0.000"	""	"19"	"5"	"7"	"4"	"370"	"41.5"	"8.18"	"1075.32"	"16.64"	"3"	"4"	"cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf00400"	"10552"	"ENSG00000241685"	"ARPC1A"	"A4D276; B4DLQ7; D6W5S1; hsa:10552; Q7Z5U8; Q86WU5; Q8IXQ0; Q92747"	"EPHB-mediated forward signaling; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis"	"Pathogenic Escherichia coli infection"	"6"	"1"	"160.4"	"68.9"	"128.5"	"107.9"	"128.1"	"153.4"	"121.4"	"161.1"	"211.1"	"1439.3"	"4454.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96RF0"	"Sorting nexin-18 OS=Homo sapiens OX=9606 GN=SNX18 PE=1 SV=2"	"0.000"	""	"11"	"5"	"8"	"5"	"628"	"68.9"	"5.68"	"1350.37"	"16.54"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00787, Pf10456, Pf14604"	"112574"	"ENSG00000178996"	"SNX18"	"B4E2B3; H7BXX3; hsa:112574; Q05BB3; Q0VG02; Q96RF0"	"Clathrin-mediated endocytosis"	""	"1"	"0"	"141.0"	"53.6"	"121.1"	"115.9"	"122.5"	"148.4"	"166.1"	"505.8"	"980.6"	"2846.2"	"1920.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92733"	"Proline-rich protein PRCC OS=Homo sapiens OX=9606 GN=PRCC PE=1 SV=1"	"0.000"	""	"13"	"5"	"6"	"5"	"491"	"52.4"	"5.10"	"884.81"	"16.49"	"2"	"4"	"cell cycle OR cell proliferation;other biological processes"	"nucleus"	""	"Pf10253"	"5546"	"ENSG00000143294"	"PRCC"	"A8K1F7; hsa:5546; O00665; O00724; Q5SZ06; Q92733"	"mRNA Splicing - Major Pathway"	"Type 2 papillary renal cell carcinoma; IL-18 signaling pathway"	"3"	"0"	"344.9"	"170.0"	"361.0"	"337.9"	"377.1"	"466.2"	"308.1"	"423.0"	"302.1"	"552.5"	"804.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92614"	"Unconventional myosin-XVIIIa OS=Homo sapiens OX=9606 GN=MYO18A PE=1 SV=3"	"0.000"	""	"3"	"4"	"10"	"4"	"2054"	"233.0"	"6.30"	"1899.43"	"16.47"	"4"	"4"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00063, Pf01576, Pf17820"	"399687"	"ENSG00000196535"	"MYO18A"	"hsa:399687; Q5H9U3; Q5QD01; Q5W9F9; Q5W9G1; Q8IXP8; Q92614"	"Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease; Signaling by FLT3 fusion proteins"	""	"3"	"0"	"28.8"	"15.4"	"31.0"	"26.1"	"27.3"	"28.6"	"28.3"	"39.4"	"34.3"	"58.1"	"94.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P016"	"Thymocyte nuclear protein 1 OS=Homo sapiens OX=9606 GN=THYN1 PE=1 SV=1"	"0.000"	""	"23"	"5"	"10"	"5"	"225"	"25.7"	"9.25"	"1729.34"	"16.45"	"5"	"5"	""	""	""	"Pf01878"	"29087"	"ENSG00000151500"	"THYN1"	"hsa:29087; Q567Q2; Q9H3L4; Q9HC20; Q9P016"	""	""	"0"	"0"	"432.3"	"203.5"	"388.2"	"371.0"	"405.0"	"478.6"	"380.4"	"562.9"	"500.4"	"1060.0"	"1586.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q09666"	"Neuroblast differentiation-associated protein AHNAK OS=Homo sapiens OX=9606 GN=AHNAK PE=1 SV=2"	"0.000"	""	"5"	"6"	"11"	"6"	"5890"	"628.7"	"6.15"	"658.27"	"16.43"	"2"	"5"	"other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	""	"79026"	"ENSG00000124942"	"AHNAK"	"A1A586; hsa:79026; Q09666"	""	""	"0"	"0"	"255.1"	"67.5"	"180.7"	"139.9"	"163.8"	"182.0"	"133.3"	"206.7"	"154.1"	"518.3"	"1274.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UNS2"	"COP9 signalosome complex subunit 3 OS=Homo sapiens OX=9606 GN=COPS3 PE=1 SV=3"	"0.000"	""	"12"	"3"	"8"	"3"	"423"	"47.8"	"6.65"	"1993.17"	"16.40"	"3"	"3"	"protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf01399"	"8533"	"ENSG00000141030"	"COPS3"	"B2R683; B4DY81; hsa:8533; O43191; Q7LDR6; Q9UNS2"	"Neddylation; Cargo recognition for clathrin-mediated endocytosis; Formation of TC-NER Pre-Incision Complex; DNA Damage Recognition in GG-NER"	"Ciliary landscape; Smith-Magenis and Potocki-Lupski syndrome copy number variation"	"6"	"0"	"54.1"	"19.8"	"44.6"	"38.5"	"39.4"	"80.4"	"103.0"	"193.4"	"162.5"	"378.8"	"1124.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35659"	"Protein DEK OS=Homo sapiens OX=9606 GN=DEK PE=1 SV=1"	"0.000"	""	"11"	"4"	"10"	"4"	"375"	"42.6"	"8.56"	"1677.05"	"16.35"	"4"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytoskeleton;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf08766"	"7913"	"ENSG00000124795"	"DEK"	"B2R6K6; B4DN37; hsa:7913; P35659; Q5TGV4; Q5TGV5"	"B-WICH complex positively regulates rRNA expression; Transcriptional regulation of granulopoiesis; Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors"	"IL-18 signaling pathway; 10q11.21q11.23 copy number variation syndrome"	"5"	"0"	"363.8"	"160.0"	"337.6"	"331.3"	"357.6"	"454.1"	"433.4"	"670.4"	"526.4"	"1008.0"	"1772.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35244"	"Replication protein A 14 kDa subunit OS=Homo sapiens OX=9606 GN=RPA3 PE=1 SV=1"	"0.000"	""	"41"	"4"	"7"	"4"	"121"	"13.6"	"5.08"	"1212.51"	"16.32"	"3"	"4"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf08661"	"6119"	"ENSG00000106399"	"RPA3"	"hsa:6119; P35244; Q549U6"	"HSF1 activation; Fanconi Anemia Pathway; Regulation of HSF1-mediated heat shock response; Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Meiotic recombination; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Removal of the Flap Intermediate; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"Retinoblastoma gene in cancer; G1 to S cell cycle control; DNA replication; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"36"	"0"	"205.3"	"79.4"	"191.2"	"166.8"	"182.8"	"221.5"	"181.8"	"213.3"	"179.5"	"327.9"	"577.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NFW8"	"N-acylneuraminate cytidylyltransferase OS=Homo sapiens OX=9606 GN=CMAS PE=1 SV=2"	"0.000"	""	"16"	"5"	"10"	"5"	"434"	"48.3"	"7.93"	"1903.26"	"16.29"	"5"	"5"	"other metabolic processes"	"nucleus"	"other molecular function"	"Pf02348"	"55907"	"ENSG00000111726"	"CMAS"	"hsa:55907; Q8NFW8; Q96AX5; Q9NQZ0"	"Sialic acid metabolism"	""	"1"	"0"	"105.0"	"43.2"	"114.7"	"90.1"	"96.2"	"125.0"	"93.8"	"114.8"	"104.8"	"497.5"	"970.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q05519"	"Serine/arginine-rich splicing factor 11 OS=Homo sapiens OX=9606 GN=SRSF11 PE=1 SV=1"	"0.000"	""	"13"	"5"	"11"	"5"	"484"	"53.5"	"10.52"	"1545.04"	"16.26"	"4"	"5"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00076"	"9295"	"ENSG00000116754"	"SRSF11"	"hsa:9295; Q05519; Q5T758; Q8IWE6"	"mRNA Splicing - Major Pathway; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript"	""	"5"	"0"	"1131.3"	"320.8"	"751.3"	"635.1"	"720.7"	"927.8"	"849.8"	"1308.5"	"912.5"	"1299.3"	"2414.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60739"	"Eukaryotic translation initiation factor 1b OS=Homo sapiens OX=9606 GN=EIF1B PE=1 SV=2"	"0.000"	""	"45"	"3"	"6"	"1"	"113"	"12.8"	"7.37"	"717.78"	"16.25"	"2"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"translational apparatus"	"translation activity;nucleic acid binding activity"	"Pf01253"	"10289"	"ENSG00000114784"	"EIF1B"	"hsa:10289; O60739; Q9UQF8"	""	""	"0"	"2"	"97.3"	"36.8"	"79.9"	"70.1"	"88.1"	"101.4"	"85.9"	"115.6"	"93.1"	"378.3"	"1720.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16698"	"2,4-dienoyl-CoA reductase, mitochondrial OS=Homo sapiens OX=9606 GN=DECR1 PE=1 SV=1"	"0.000"	""	"18"	"4"	"7"	"4"	"335"	"36.0"	"9.28"	"1315.31"	"16.23"	"3"	"4"	"other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf13561"	"1666"	"ENSG00000104325"	"DECR1"	"B7Z6B8; hsa:1666; Q16698; Q2M304; Q93085"	"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids"	"Fatty acid beta-oxidation; Fatty acid biosynthesis; VEGFA-VEGFR2 signaling"	"4"	"0"	"211.3"	"81.9"	"175.1"	"144.0"	"180.6"	"198.2"	"164.1"	"219.2"	"199.3"	"376.4"	"746.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16629"	"Serine/arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1"	"0.000"	""	"24"	"4"	"9"	"4"	"238"	"27.4"	"11.82"	"1191.33"	"16.23"	"2"	"4"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6432"	"ENSG00000115875"	"SRSF7"	"B4DLU6; G5E9M3; hsa:6432; Q16629; Q564D3"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"mRNA processing"	"7"	"0"	"1092.7"	"306.4"	"530.2"	"435.7"	"495.6"	"560.5"	"550.5"	"681.1"	"733.6"	"1397.4"	"2740.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00303"	"Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1"	"0.000"	""	"15"	"5"	"10"	"5"	"357"	"37.5"	"5.45"	"1755.78"	"16.22"	"5"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01398, Pf13012"	"8665"	"ENSG00000175390"	"EIF3F"	"A8K0S2; hsa:8665; O00303; Q6IB45; Q8N978"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"Translation factors; VEGFA-VEGFR2 signaling; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"9"	"0"	"516.6"	"200.6"	"485.7"	"445.2"	"457.2"	"584.7"	"421.8"	"489.0"	"358.0"	"712.6"	"1241.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16795"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFA9 PE=1 SV=2"	"0.000"	""	"14"	"3"	"6"	"3"	"377"	"42.5"	"9.80"	"1562.67"	"16.20"	"3"	"3"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf01370"	"4704"	"ENSG00000139180"	"NDUFA9"	"hsa:4704; Q14076; Q16795; Q2NKX0"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Ciliary landscape; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"6"	"0"	"148.7"	"45.0"	"109.8"	"91.7"	"106.9"	"129.7"	"90.4"	"151.8"	"109.6"	"253.8"	"694.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12769"	"Nuclear pore complex protein Nup160 OS=Homo sapiens OX=9606 GN=NUP160 PE=1 SV=3"	"0.000"	""	"4"	"5"	"10"	"5"	"1436"	"162.0"	"5.50"	"2004.54"	"16.20"	"5"	"5"	"other metabolic processes;transport;developmental processes"	"cytosol;nucleus"	"other molecular function"	"Pf11715"	"23279"	"ENSG00000030066"	"NUP160"	"B4DYE8; B4E2J9; hsa:23279; Q08AD3; Q12769; Q7Z5X6; Q96GB3; Q9H660"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; HCMV Early Events; EML4 and NUDC in mitotic spindle formation; Rev-mediated nuclear export of HIV RNA; Nuclear import of Rev protein; Postmitotic nuclear pore complex (NPC) reformation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; HCMV Late Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	""	"35"	"0"	"497.7"	"251.9"	"504.5"	"478.3"	"444.1"	"570.3"	"435.8"	"450.7"	"385.9"	"581.6"	"905.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P22033"	"Methylmalonyl-CoA mutase, mitochondrial OS=Homo sapiens OX=9606 GN=MMUT PE=1 SV=4"	""	""	"8"	"5"	"5"	"5"	"750"	"83.1"	"6.93"	""	"16.15"	""	"5"	"other metabolic processes;developmental processes;other biological processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf01642, Pf02310"	"4594"	"ENSG00000146085"	"MMUT"	"A8K953; hsa:4594; P22033; Q5SYZ3; Q96B11; Q9UD64"	"Propionyl-CoA catabolism; Defective MMAA causes MMA, cblA type; Defective MUT causes MMAM; Cobalamin (Cbl) metabolism"	"Vitamin B12 metabolism; Amino acid metabolism"	"6"	"0"	"110.6"	"46.3"	"101.3"	"92.0"	"107.9"	"118.6"	"87.9"	"137.2"	"157.2"	"705.8"	"2052.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26358"	"DNA (cytosine-5)-methyltransferase 1 OS=Homo sapiens OX=9606 GN=DNMT1 PE=1 SV=2"	"0.000"	""	"5"	"6"	"11"	"6"	"1616"	"183.1"	"7.75"	"2279.83"	"16.11"	"6"	"5"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00145, Pf01426, Pf02008, Pf06464, Pf12047"	"1786"	"ENSG00000130816"	"DNMT1"	"A0AV63; B7ZLW6; hsa:1786; P26358; Q9UHG5; Q9ULA2; Q9UMZ6"	"SUMOylation of DNA methylation proteins; NoRC negatively regulates rRNA expression; PRC2 methylates histones and DNA; Defective pyroptosis; DNA methylation"	"Trans-sulfuration pathway; One-carbon metabolism; Retinoblastoma gene in cancer; Hematopoietic stem cell gene regulation by GABP alpha/beta complex; MTHFR deficiency"	"10"	"0"	"222.6"	"111.0"	"187.9"	"173.0"	"181.6"	"209.9"	"135.5"	"203.6"	"153.4"	"377.6"	"791.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3B4"	"Splicing factor 3B subunit 6 OS=Homo sapiens OX=9606 GN=SF3B6 PE=1 SV=1"	"0.000"	""	"30"	"3"	"9"	"3"	"125"	"14.6"	"9.38"	"1185.00"	"16.08"	"2"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"51639"	"ENSG00000115128"	"SF3B6"	"hsa:51639; Q53TM1; Q9Y3B4"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	""	"2"	"0"	"468.9"	"132.5"	"339.6"	"227.4"	"310.3"	"370.1"	"271.2"	"342.2"	"309.4"	"474.6"	"891.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99873"	"Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3"	"0.000"	""	"16"	"5"	"10"	"5"	"371"	"42.4"	"5.35"	"1688.58"	"16.08"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13649"	"3276"	"ENSG00000126457"	"PRMT1"	"A0A087X1W2; B4E3C3; G5E9B6; H7C2I1; hsa:3276; Q15529; Q2VP93; Q6LEU5; Q8WUW5; Q99872; Q99873; Q99874; Q9NZ04; Q9NZ05; Q9NZ06"	"Estrogen-dependent gene expression; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Extra-nuclear estrogen signaling; RMTs methylate histone arginines; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Maturation of nucleoprotein"	"Energy metabolism; mRNA processing; Nitric oxide metabolism in cystic fibrosis; 16p11.2 distal deletion syndrome; Interferon type I signaling pathways"	"11"	"0"	"336.7"	"131.9"	"291.3"	"248.5"	"274.4"	"340.8"	"277.9"	"351.9"	"338.6"	"590.3"	"993.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60885"	"Bromodomain-containing protein 4 OS=Homo sapiens OX=9606 GN=BRD4 PE=1 SV=2"	"0.000"	""	"4"	"5"	"10"	"5"	"1362"	"152.1"	"9.19"	"1767.89"	"16.07"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00439, Pf17035, Pf17105"	"23476"	"ENSG00000141867"	"BRD4"	"hsa:23476; O60433; O60885; Q4G0X8; Q86YS8; Q96PD3"	"Potential therapeutics for SARS"	"VEGFA-VEGFR2 signaling; 7q11.23 copy number variation syndrome"	"3"	"0"	"524.0"	"210.7"	"399.6"	"369.6"	"406.5"	"471.4"	"352.3"	"562.2"	"457.8"	"919.2"	"1679.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62861"	"40S ribosomal protein S30 OS=Homo sapiens OX=9606 GN=FAU PE=1 SV=1"	"0.000"	""	"20"	"3"	"9"	"3"	"59"	"6.6"	"12.15"	"1254.87"	"16.02"	"3"	"3"	"protein metabolism;other metabolic processes;stress response"	"non-structural extracellular;cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf04758"	""	"ENSCHIG00000017446; ENSJHYG00000000624; ENSLLEG00000000574"	"Fau; FAU"	"A0A452F0A8; A0A7L0YXB0; A0A8C5IE60; A0A8C5LQJ8; P0C2F0; P62860; P62863; P62864; P62866; P62867; Q05472; Q5RC12; Q8HYI8; Q920W7; Q95261"	""	""	"0"	"0"	"651.4"	"389.2"	"592.1"	"546.0"	"553.2"	"736.4"	"546.0"	"705.6"	"570.8"	"855.6"	"1306.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O96000"	"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 OS=Homo sapiens OX=9606 GN=NDUFB10 PE=1 SV=3"	"0.000"	""	"38"	"5"	"10"	"5"	"172"	"20.8"	"8.48"	"1723.19"	"16.01"	"5"	"5"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf10249"	"4716"	"ENSG00000140990"	"NDUFB10"	"hsa:4716; O96000; Q96II6"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Modulators of TCR signaling and T cell activation; Oxidative phosphorylation"	"6"	"0"	"231.4"	"87.7"	"130.4"	"118.7"	"156.6"	"141.4"	"144.4"	"188.5"	"191.0"	"435.8"	"954.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P06753"	"Tropomyosin alpha-3 chain OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=2"	"0.000"	""	"19"	"6"	"12"	"6"	"285"	"32.9"	"4.72"	"2037.22"	"16.01"	"5"	"5"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	"cytoskeletal activity"	"Pf00261"	"7170"	"ENSG00000143549"	"TPM3"	"D3DV71; hsa:7170; P06753; P12324; Q2QD06; Q5VU58; Q5VU63; Q5VU66; Q5VU71; Q5VU72; Q8TCG3; Q969Q2; Q9NQH8"	"RHOV GTPase cycle; Signaling by ALK fusions and activated point mutants; Smooth Muscle Contraction; Striated Muscle Contraction"	"Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4); Striated muscle contraction pathway; VEGFA-VEGFR2 signaling"	"7"	"0"	"1882.0"	"672.6"	"1575.0"	"1388.5"	"1737.0"	"1728.0"	"1210.0"	"1628.6"	"1079.9"	"2030.7"	"3730.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92820"	"Gamma-glutamyl hydrolase OS=Homo sapiens OX=9606 GN=GGH PE=1 SV=2"	"0.000"	""	"23"	"7"	"15"	"7"	"318"	"35.9"	"7.11"	"1994.34"	"15.99"	"7"	"6"	"other metabolic processes"	"non-structural extracellular;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf07722"	"8836"	"ENSG00000137563"	"GGH"	"hsa:8836; Q92820"	"Neutrophil degranulation"	"Fluoropyrimidine activity"	"2"	"0"	"173.5"	"84.8"	"167.8"	"140.1"	"169.4"	"206.1"	"206.3"	"561.5"	"875.1"	"1917.2"	"2244.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q07157"	"Tight junction protein ZO-1 OS=Homo sapiens OX=9606 GN=TJP1 PE=1 SV=3"	"0.000"	""	"4"	"5"	"8"	"5"	"1748"	"195.3"	"6.70"	"1746.36"	"15.98"	"4"	"4"	"cell adhesion;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00595, Pf00625, Pf00791, Pf07653"	"7082"	"ENSG00000104067; ENSG00000277401"	"TJP1"	"B4E3K1; hsa:7082; Q07157; Q2NKP3; Q4ZGJ6"	"RUNX1 regulates expression of components of tight junctions; Signaling by Hippo; Regulation of gap junction activity; SARS-CoV-2 targets PDZ proteins in cell-cell junction; Apoptotic cleavage of cell adhesion  proteins"	"Epithelial to mesenchymal transition in colorectal cancer; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Gastrin signaling pathway; Disruption of postsynaptic signaling by CNV; 1q21.1 copy number variation syndrome; CKAP4 signaling pathway map; 15q11q13 copy number variation"	"12"	"0"	"411.5"	"171.0"	"316.9"	"298.5"	"325.4"	"355.7"	"275.8"	"401.5"	"328.2"	"677.5"	"1138.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EE3"	"Nucleoporin SEH1 OS=Homo sapiens OX=9606 GN=SEH1L PE=1 SV=3"	"0.000"	""	"11"	"2"	"5"	"2"	"360"	"39.6"	"8.09"	"904.89"	"15.97"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;other biological processes"	"other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00400"	"81929"	"ENSG00000085415"	"SEH1L"	"A8K5B1; hsa:81929; Q8NFU6; Q96EE3; Q96MH3; Q9C069"	"Amino acids regulate mTORC1"	""	"1"	"0"	"67.8"	"32.0"	"69.8"	"73.2"	"65.2"	"84.3"	"64.8"	"90.8"	"81.4"	"147.7"	"195.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5T2T1"	"MAGUK p55 subfamily member 7 OS=Homo sapiens OX=9606 GN=MPP7 PE=1 SV=1"	"0.000"	""	"11"	"4"	"8"	"4"	"576"	"65.5"	"7.14"	"1458.73"	"15.95"	"4"	"4"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00018, Pf00595, Pf00625, Pf02828"	"143098"	"ENSG00000150054"	"MPP7"	"B2RCC9; B4DWL9; B5MDZ3; D3DRW3; hsa:143098; Q5T2T0; Q5T2T1; Q8IY28"	"RAC1 GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOJ GTPase cycle; RHOQ GTPase cycle"	""	"6"	"0"	"108.2"	"49.2"	"102.5"	"94.1"	"92.0"	"118.9"	"76.8"	"113.2"	"97.9"	"287.7"	"882.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P34896"	"Serine hydroxymethyltransferase, cytosolic OS=Homo sapiens OX=9606 GN=SHMT1 PE=1 SV=1"	"0.000"	""	"5"	"2"	"9"	"1"	"483"	"53.0"	"7.71"	"1413.66"	"15.94"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00464"	"6470"	"ENSG00000176974; ENSG00000284320"	"SHMT1"	"B4DPM9; D3DXD0; hsa:6470; P34896; Q96HY0; Q9UMD1; Q9UMD2"	"Metabolism of folate and pterines; Carnitine synthesis"	"Glycine metabolism; Folate metabolism; One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways; Clear cell renal cell carcinoma pathways; Male infertility; Neuroinflammation and glutamatergic signaling; Metabolic Epileptic Disorders; Smith-Magenis and Potocki-Lupski syndrome copy number variation"	"11"	"0"	"16.7"	"2.6"	"9.0"	"9.3"	"10.2"	"12.1"	"11.2"	"9.0"	"9.5"	"13.0"	"30.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P41252"	"Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2"	"0.000"	""	"5"	"5"	"10"	"5"	"1262"	"144.4"	"6.15"	"1804.86"	"15.88"	"4"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00133, Pf08264, Pf19302"	"3376"	"ENSG00000196305"	"IARS1"	"A8KAE9; hsa:3376; P41252; Q5TCD0; Q7Z3T4; Q9H588"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"Amino acid metabolism"	"3"	"0"	"381.6"	"137.1"	"283.7"	"231.6"	"281.0"	"326.0"	"264.9"	"339.7"	"333.5"	"736.1"	"2616.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15530"	"3-phosphoinositide-dependent protein kinase 1 OS=Homo sapiens OX=9606 GN=PDPK1 PE=1 SV=1"	"0.000"	""	"6"	"2"	"6"	"2"	"556"	"63.1"	"7.36"	"1497.10"	"15.88"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf14593"	"5170"	"ENSG00000140992"	"PDPK1"	"H0Y4Z0; hsa:5170; O15530; Q59EH6; Q6FI20; Q8IV52; Q9BRD5"	"Role of LAT2/NTAL/LAB on calcium mobilization; FCERI mediated NF-kB activation; Downstream TCR signaling; CLEC7A (Dectin-1) signaling; Constitutive Signaling by AKT1 E17K in Cancer; PIP3 activates AKT signaling; Regulation of TP53 Degradation; GPVI-mediated activation cascade; CD28 dependent PI3K/Akt signaling; G beta:gamma signalling through PI3Kgamma; RHO GTPases activate PKNs; Activation of AKT2; Integrin signaling; RSK activation; VEGFR2 mediated vascular permeability; VEGFR2 mediated cell proliferation; Estrogen-stimulated signaling through PRKCZ; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways"	"MicroRNAs in cardiomyocyte hypertrophy; Integrin-mediated cell adhesion; Thyroid stimulating hormone (TSH) signaling pathway; Glioblastoma signaling pathways; B cell receptor signaling pathway; Interleukin-11 signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Cardiac hypertrophic response; Focal adhesion; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Leptin-insulin signaling overlap; PPAR signaling pathway; Endometrial cancer; PI3K-Akt signaling pathway; EGF/EGFR signaling pathway; Head and neck squamous cell carcinoma; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; Modulators of TCR signaling and T cell activation; GDNF signaling; Primary ovarian insufficiency; A network map of Macrophage-stimulating protein (MSP) signaling; ErbB signaling pathway; T-cell receptor signaling pathway; Serotonin HTR1 group and FOS pathway"	"46"	"0"	"18.5"	"8.4"	"22.7"	"22.6"	"19.6"	"44.8"	"63.4"	"156.8"	"156.7"	"312.1"	"520.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23921"	"Ribonucleoside-diphosphate reductase large subunit OS=Homo sapiens OX=9606 GN=RRM1 PE=1 SV=1"	"0.000"	""	"7"	"4"	"7"	"4"	"792"	"90.0"	"7.15"	"1162.44"	"15.88"	"3"	"4"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf00317, Pf02867, Pf03477"	"6240"	"ENSG00000167325"	"RRM1"	"hsa:6240; P23921; Q9UNN2"	"Interconversion of nucleotide di- and triphosphates"	"Fluoropyrimidine activity; Retinoblastoma gene in cancer; Pyrimidine metabolism"	"4"	"0"	"183.8"	"88.4"	"160.5"	"160.2"	"159.1"	"185.3"	"145.2"	"165.1"	"139.1"	"446.8"	"1496.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P20618"	"Proteasome subunit beta type-1 OS=Homo sapiens OX=9606 GN=PSMB1 PE=1 SV=2"	"0.000"	""	"24"	"4"	"9"	"4"	"241"	"26.5"	"8.13"	"1762.46"	"15.86"	"4"	"3"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf00227"	"5689"	"ENSG00000008018"	"PSMB1"	"B5BU76; hsa:5689; P20618; Q9BWA8"	"Neutrophil degranulation; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; MAPK6/MAPK4 signaling; The role of GTSE1 in G2/M progression after G2 checkpoint; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"63"	"0"	"424.0"	"182.6"	"383.8"	"394.8"	"399.1"	"478.7"	"385.1"	"482.7"	"377.9"	"670.3"	"1141.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H7Z3"	"Nuclear exosome regulator NRDE2 OS=Homo sapiens OX=9606 GN=NRDE2 PE=1 SV=3"	"0.000"	""	"4"	"4"	"7"	"4"	"1164"	"132.6"	"7.68"	"669.84"	"15.84"	"2"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus"	""	"Pf08424"	"55051"	"ENSG00000119720"	"NRDE2"	"B4DH71; hsa:55051; Q4G0A7; Q9H7Z3; Q9NWH6"	""	""	"0"	"0"	"99.5"	"39.1"	"91.0"	"77.0"	"87.8"	"92.4"	"67.0"	"116.1"	"97.4"	"590.3"	"1442.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P04908"	"Histone H2A type 1-B/E OS=Homo sapiens OX=9606 GN=H2AC4 PE=1 SV=2"	"0.000"	""	"27"	"3"	"11"	"1"	"130"	"14.1"	"11.05"	"1536.29"	"15.83"	"3"	"3"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125, Pf16211"	"3012; 8335"	"ENSG00000277075; ENSG00000278463"	"H2AC4; H2AC8"	"hsa:3012; hsa:8335; P04908; P28001; Q76P63"	"HCMV Early Events; Deposition of new CENPA-containing nucleosomes at the centromere; B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; Amyloid fiber formation; Meiotic synapsis; HCMV Late Events; UCH proteinases; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Transcriptional regulation by small RNAs; Formation of the beta-catenin:TCF transactivating complex; Oxidative Stress Induced Senescence; HDACs deacetylate histones; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Metalloprotease DUBs; Pre-NOTCH Transcription and Translation; Senescence-Associated Secretory Phenotype (SASP); RMTs methylate histone arginines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; HATs acetylate histones; RNA Polymerase I Promoter Escape; Meiotic recombination; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Packaging Of Telomere Ends; Condensation of Prophase Chromosomes; DNA Damage/Telomere Stress Induced Senescence; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	"Proteasome degradation"	"42"	"2"	"1334.5"	"545.6"	"1145.1"	"841.2"	"1120.1"	"1312.2"	"990.9"	"1025.6"	"775.1"	"1235.3"	"1233.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TDN6"	"Ribosome biogenesis protein BRX1 homolog OS=Homo sapiens OX=9606 GN=BRIX1 PE=1 SV=2"	"0.000"	""	"13"	"4"	"8"	"4"	"353"	"41.4"	"9.92"	"1185.44"	"15.82"	"3"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf04427"	"55299"	"ENSG00000113460"	"BRIX1"	"A8K0P5; hsa:55299; Q3ZTT4; Q8N453; Q8TDN6; Q96DH1"	""	"Gastric cancer network 2"	"1"	"0"	"274.8"	"111.6"	"230.0"	"211.4"	"258.8"	"279.9"	"204.8"	"273.3"	"224.2"	"376.3"	"684.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IYB3"	"Serine/arginine repetitive matrix protein 1 OS=Homo sapiens OX=9606 GN=SRRM1 PE=1 SV=2"	"0.000"	""	"5"	"3"	"6"	"3"	"904"	"102.3"	"11.84"	"1633.49"	"15.79"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity"	"Pf01480"	"10250"	"ENSG00000133226"	"SRRM1"	"hsa:10250; O60585; Q5VVN4; Q8IYB3"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; RHOBTB1 GTPase cycle; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA Splicing - Major Pathway; RHOBTB2 GTPase cycle"	"mRNA processing"	"7"	"0"	"514.8"	"142.6"	"425.2"	"340.1"	"423.9"	"585.1"	"561.1"	"855.2"	"527.2"	"675.8"	"960.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62847"	"40S ribosomal protein S24 OS=Homo sapiens OX=9606 GN=RPS24 PE=1 SV=1"	"0.000"	""	"31"	"4"	"9"	"4"	"133"	"15.4"	"10.78"	"1741.17"	"15.76"	"3"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01282"	"6229"	"ENSG00000138326"	"RPS24"	"E7EPK6; hsa:6229; P16632; P62847; Q5T0P7; Q5T0P8; Q7Z3D1"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"364.7"	"153.4"	"284.8"	"298.6"	"328.4"	"371.2"	"257.5"	"363.2"	"308.5"	"590.6"	"993.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P04843"	"Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1"	"0.000"	""	"9"	"4"	"8"	"4"	"607"	"68.5"	"6.38"	"1462.26"	"15.74"	"4"	"4"	"protein metabolism;other metabolic processes"	"other membranes;cytosol;ER/Golgi;other cell component"	""	"Pf04597"	"6184"	"ENSG00000163902"	"RPN1"	"B2R5Z0; D3DNB6; hsa:6184; P04843; Q68DT1"	"SRP-dependent cotranslational protein targeting to membrane; Asparagine N-linked glycosylation; Maturation of spike protein"	"Proteasome degradation; N-glycan biosynthesis"	"5"	"0"	"153.1"	"70.4"	"129.2"	"93.3"	"114.6"	"105.5"	"109.5"	"143.8"	"165.7"	"328.8"	"724.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23588"	"Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2"	"0.000"	""	"10"	"7"	"12"	"7"	"611"	"69.1"	"5.73"	"2813.00"	"15.71"	"7"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus"	"nucleic acid binding activity"	"Pf00076"	"1975"	"ENSG00000063046"	"EIF4B"	"B4DS13; hsa:1975; P23588; Q4G0E3; Q53HQ2; Q6GPH5; Q6IB46; Q8WYK5"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Deadenylation of mRNA; mTORC1-mediated signalling"	"Translation factors; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Translation inhibitors in chronically activated PDGFRA cells; Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins; Pleural mesothelioma; Interferon type I signaling pathways"	"14"	"0"	"1115.2"	"465.3"	"957.0"	"893.5"	"998.8"	"1126.6"	"877.7"	"1207.9"	"855.2"	"1457.7"	"2509.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKA9"	"Polypyrimidine tract-binding protein 2 OS=Homo sapiens OX=9606 GN=PTBP2 PE=1 SV=1"	"0.000"	""	"4"	"3"	"15"	"1"	"531"	"57.5"	"8.66"	"2746.02"	"15.65"	"3"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf11835, Pf13893"	"58155"	"ENSG00000117569"	"PTBP2"	"hsa:58155; Q8N0Z1; Q8N160; Q8NFB0; Q8NFB1; Q969N9; Q96Q76; Q9UKA9"	""	"Genes targeted by miRNAs in adipocytes; mRNA processing"	"2"	"0"	"140.7"	"50.9"	"117.4"	"90.3"	"113.8"	"110.5"	"87.3"	"138.6"	"110.8"	"229.8"	"484.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86VP6"	"Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2"	"0.000"	""	"4"	"4"	"10"	"4"	"1230"	"136.3"	"5.78"	"1663.09"	"15.63"	"4"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf08623"	"55832"	"ENSG00000111530"	"CAND1"	"B2RAU3; hsa:55832; O94918; Q6PIY4; Q86VP6; Q8NDJ4; Q96JZ9; Q96T19; Q9BTC4; Q9H0G2; Q9P0H7; Q9UF85"	"Neutrophil degranulation; Neddylation; Iron uptake and transport"	"Endoderm differentiation"	"4"	"0"	"143.7"	"62.8"	"117.7"	"91.2"	"125.0"	"140.3"	"114.3"	"161.1"	"150.8"	"481.7"	"736.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NTJ3"	"Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2"	"0.000"	""	"5"	"5"	"10"	"5"	"1288"	"147.1"	"6.79"	"1923.89"	"15.61"	"5"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463, Pf06470"	"10051"	"ENSG00000113810"	"SMC4"	"A6NLT9; D3DNL8; hsa:10051; O95752; Q8NDL4; Q9NTJ3; Q9UNT9"	"Condensation of Prophase Chromosomes; Condensation of Prometaphase Chromosomes"	"Ciliary landscape"	"3"	"0"	"106.8"	"45.5"	"96.4"	"88.1"	"107.8"	"115.5"	"84.1"	"118.3"	"103.5"	"291.0"	"504.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P0C7P4"	"Putative cytochrome b-c1 complex subunit Rieske-like protein 1 OS=Homo sapiens OX=9606 GN=UQCRFS1P1 PE=5 SV=1"	"0.000"	""	"16"	"5"	"7"	"5"	"283"	"30.8"	"8.87"	"704.35"	"15.60"	"2"	"5"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00355, Pf02921, Pf09165"	""	""	"UQCRFS1P1"	"P0C7P4"	""	""	"0"	"0"	"854.6"	"546.7"	"908.9"	"717.0"	"814.3"	"950.3"	"697.0"	"1033.0"	"839.2"	"1588.8"	"2127.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q52LJ0"	"Protein FAM98B OS=Homo sapiens OX=9606 GN=FAM98B PE=1 SV=2"	"0.000"	""	"13"	"4"	"8"	"4"	"433"	"45.5"	"8.69"	"1410.34"	"15.60"	"4"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf10239"	"283742"	"ENSG00000171262"	"FAM98B"	"A8MUW5; hsa:283742; Q52LJ0; Q8N935"	"tRNA processing in the nucleus"	""	"1"	"0"	"49.2"	"21.8"	"39.7"	"32.8"	"33.9"	"47.5"	"33.0"	"44.3"	"41.2"	"70.9"	"103.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P16989"	"Y-box-binding protein 3 OS=Homo sapiens OX=9606 GN=YBX3 PE=1 SV=4"	"0.000"	""	"13"	"3"	"7"	"1"	"372"	"40.1"	"9.77"	"1172.00"	"15.55"	"3"	"3"	"stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00313"	"8531"	"ENSG00000060138"	"YBX3"	"B2RBW6; hsa:8531; P16989; Q14121; Q969N6; Q96B76"	""	"RalA downstream regulated genes; Apoptosis-related network due to altered Notch3 in ovarian cancer"	"2"	"0"	"84.0"	"39.5"	"75.8"	"66.1"	"65.3"	"73.8"	"63.1"	"72.9"	"61.8"	"153.1"	"330.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"E9PAV3"	"Nascent polypeptide-associated complex subunit alpha, muscle-specific form OS=Homo sapiens OX=9606 GN=NACA PE=1 SV=1"	"0.000"	""	"3"	"4"	"8"	"4"	"2078"	"205.3"	"9.58"	"1646.98"	"15.52"	"4"	"4"	"transport"	"translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01849, Pf19026"	""	"ENSG00000196531"	"NACA"	"E9PAV3"	""	""	"0"	"0"	"288.6"	"99.6"	"199.7"	"189.1"	"222.1"	"389.5"	"489.4"	"818.5"	"840.4"	"703.8"	"602.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49368"	"T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4"	"0.000"	""	"18"	"9"	"14"	"9"	"545"	"60.5"	"6.49"	"2843.43"	"15.47"	"9"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00118"	"7203"	"ENSG00000163468"	"CCT3"	"A6NE14; hsa:7203; P49368; Q5SZY1; Q9BR64"	"Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"16p11.2 proximal deletion syndrome"	"7"	"0"	"1312.8"	"587.1"	"1080.6"	"882.7"	"1038.8"	"1194.6"	"933.7"	"1101.4"	"939.0"	"1607.2"	"3347.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O60934"	"Nibrin OS=Homo sapiens OX=9606 GN=NBN PE=1 SV=1"	""	""	"8"	"4"	"4"	"4"	"754"	"84.9"	"6.90"	""	"15.46"	""	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00498, Pf08599, Pf16508"	"4683"	"ENSG00000104320"	"NBN"	"B2R626; B2RNC5; hsa:4683; O60672; O60934; Q32NF7; Q53FM6; Q63HR6; Q7LDM2"	"Resolution of D-loop Structures through Holliday Junction Intermediates; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; Meiotic recombination; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; DNA Damage/Telomere Stress Induced Senescence; Nonhomologous End-Joining (NHEJ); HDR through MMEJ (alt-NHEJ); Sensing of DNA Double Strand Breaks"	"miRNA regulation of DNA damage response; Homologous recombination; DDX1 as a regulatory component of the Drosha microprocessor; ATM signaling in development and disease ; Breast cancer pathway; DNA repair pathways, full network; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; Primary ovarian insufficiency; DNA damage response"	"29"	"0"	"72.1"	"23.6"	"55.2"	"60.4"	"60.4"	"64.9"	"53.4"	"72.1"	"83.7"	"348.8"	"1178.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52298"	"Nuclear cap-binding protein subunit 2 OS=Homo sapiens OX=9606 GN=NCBP2 PE=1 SV=1"	"0.000"	""	"28"	"4"	"10"	"4"	"156"	"18.0"	"8.21"	"1652.46"	"15.45"	"4"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"22916"	"ENSG00000114503"	"NCBP2"	"B2RE91; B4DMK7; E9PAR5; hsa:22916; P52298; Q14924; Q2TS50"	"mRNA Splicing - Major Pathway; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Abortive elongation of HIV-1 transcript in the absence of Tat; RNA Polymerase II Pre-transcription Events; RNA polymerase II transcribes snRNA genes; mRNA Capping; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Signaling by FGFR2 IIIa TM; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; snRNP Assembly; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"mRNA processing; 3q29 copy number variation syndrome"	"29"	"0"	"834.2"	"245.8"	"683.2"	"564.5"	"625.9"	"775.6"	"576.7"	"769.5"	"603.7"	"1241.9"	"3065.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UH65"	"Switch-associated protein 70 OS=Homo sapiens OX=9606 GN=SWAP70 PE=1 SV=1"	"0.000"	""	"9"	"5"	"7"	"5"	"585"	"69.0"	"5.87"	"700.70"	"15.43"	"2"	"5"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00169"	"23075"	"ENSG00000133789"	"SWAP70"	"D3DQV1; hsa:23075; O75135; Q7LCY6; Q9P061; Q9P0Z8; Q9UH65"	"RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle"	""	"3"	"0"	"224.2"	"70.6"	"174.0"	"149.2"	"189.3"	"185.7"	"136.3"	"218.3"	"193.0"	"1027.7"	"3248.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P289"	"Serine/threonine-protein kinase 26 OS=Homo sapiens OX=9606 GN=STK26 PE=1 SV=2"	"0.000"	""	"10"	"5"	"11"	"5"	"416"	"46.5"	"5.29"	"1482.23"	"15.39"	"4"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"51765"	"ENSG00000134602"	"STK26"	"B2RAU2; hsa:51765; Q3ZB77; Q8NC04; Q9BXC3; Q9BXC4; Q9P289"	"Apoptotic cleavage of cellular proteins"	""	"1"	"0"	"626.0"	"303.2"	"583.0"	"480.8"	"570.3"	"680.1"	"503.2"	"662.4"	"525.8"	"797.2"	"1158.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19784"	"Casein kinase II subunit alpha' OS=Homo sapiens OX=9606 GN=CSNK2A2 PE=1 SV=1"	"0.000"	""	"13"	"5"	"11"	"4"	"350"	"41.2"	"8.56"	"1861.43"	"15.39"	"4"	"4"	"cell-cell signaling;cell cycle OR cell proliferation;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1459"	"ENSG00000070770"	"CSNK2A2"	"hsa:1459; P19784"	"Regulation of PTEN stability and activity; KEAP1-NFE2L2 pathway; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Regulation of TP53 Activity through Phosphorylation; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; WNT mediated activation of DVL; Signal transduction by L1; Receptor Mediated Mitophagy; Condensation of Prometaphase Chromosomes; Synthesis of PC"	"Alzheimer's disease and miRNA effects; Allograft rejection; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Measles virus infection; Pleural mesothelioma; Alzheimer's disease"	"19"	"0"	"375.0"	"184.7"	"383.6"	"370.0"	"369.7"	"490.9"	"390.0"	"484.1"	"472.4"	"888.0"	"1457.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62906"	"60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2"	"0.000"	""	"25"	"6"	"13"	"6"	"217"	"24.8"	"9.94"	"3749.66"	"15.34"	"6"	"5"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf00687"	"4736"	"ENSG00000198755"	"RPL10A"	"B2R801; hsa:4736; P52859; P53025; P62906; Q5TZT6; Q8J013"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"15"	"0"	"1168.6"	"431.7"	"1008.4"	"823.8"	"955.9"	"1210.6"	"817.9"	"1104.7"	"742.5"	"1190.5"	"1992.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UQ16"	"Dynamin-3 OS=Homo sapiens OX=9606 GN=DNM3 PE=1 SV=4"	"0.000"	""	"6"	"4"	"9"	"1"	"869"	"97.7"	"8.35"	"1371.96"	"15.31"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00169, Pf00350, Pf01031, Pf02212"	"26052"	"ENSG00000197959"	"DNM3"	"A9Z1Y1; hsa:26052; O14982; O95555; Q1MTM8; Q5W129; Q6P2G1; Q9H0P3; Q9H548; Q9NQ68; Q9NQN6; Q9UQ16"	"Recycling pathway of L1; MHC class II antigen presentation; Toll Like Receptor 4 (TLR4) Cascade; Clathrin-mediated endocytosis; Retrograde neurotrophin signalling"	"Synaptic vesicle pathway; Alstrom syndrome; 15q25 copy number variation"	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P29966"	"Myristoylated alanine-rich C-kinase substrate OS=Homo sapiens OX=9606 GN=MARCKS PE=1 SV=4"	"0.000"	""	"9"	"2"	"6"	"2"	"332"	"31.5"	"4.45"	"1553.31"	"15.28"	"2"	"2"	"cell organization and biogenesis;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02063"	"4082"	"ENSG00000277443"	"MARCKS"	"E1P560; hsa:4082; P29966; Q2LA83; Q5TDB7"	"Acetylcholine regulates insulin secretion"	"Brain-derived neurotrophic factor (BDNF) signaling pathway"	"2"	"0"	"481.5"	"204.8"	"379.7"	"335.8"	"417.9"	"446.9"	"375.0"	"470.9"	"422.2"	"644.5"	"1947.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UPT5"	"Exocyst complex component 7 OS=Homo sapiens OX=9606 GN=EXOC7 PE=1 SV=3"	"0.000"	""	"7"	"4"	"6"	"4"	"735"	"83.3"	"6.79"	"843.84"	"15.23"	"2"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf03081"	"23265"	"ENSG00000182473"	"EXOC7"	"B5MC69; B8XXP2; hsa:23265; Q8ND93; Q8WV91; Q96FF0; Q9H8C3; Q9H9X3; Q9HA32; Q9UPT5"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"Angiopoietin-like protein 8 regulatory pathway; Ciliary landscape"	"5"	"0"	"145.3"	"55.5"	"150.5"	"150.4"	"172.3"	"198.0"	"137.1"	"258.9"	"259.1"	"773.4"	"1546.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16352"	"Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2"	"0.000"	""	"14"	"7"	"13"	"4"	"499"	"55.4"	"5.40"	"2502.44"	"15.23"	"7"	"5"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00038, Pf04732"	"9118"	"ENSG00000148798"	"INA"	"B1AQK0; hsa:9118; Q16352; Q9BRC5"	""	""	"0"	"0"	"638.4"	"189.0"	"395.6"	"300.9"	"413.3"	"430.4"	"307.3"	"447.9"	"362.6"	"654.8"	"1201.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95639"	"Cleavage and polyadenylation specificity factor subunit 4 OS=Homo sapiens OX=9606 GN=CPSF4 PE=1 SV=1"	"0.000"	""	"21"	"4"	"7"	"4"	"269"	"30.2"	"8.31"	"1231.26"	"15.22"	"3"	"4"	""	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00098, Pf00642, Pf15663"	"10898"	"ENSG00000160917"	"CPSF4"	"D6W5S8; hsa:10898; O95639; Q6FGE6; Q86TF8; Q9BTW6"	"Transport of Mature mRNA Derived from an Intronless Transcript; tRNA processing in the nucleus; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; Inhibition of Host mRNA Processing and RNA Silencing"	"mRNA processing"	"8"	"0"	"266.1"	"95.8"	"199.8"	"179.4"	"176.0"	"231.7"	"168.3"	"221.5"	"203.2"	"289.9"	"501.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q7Z6Z7"	"E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3"	""	""	"2"	"3"	"4"	"3"	"4374"	"481.6"	"5.22"	""	"15.18"	""	"3"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00627, Pf00632, Pf02825, Pf06012, Pf06025, Pf14377"	"10075"	"ENSG00000086758"	"HUWE1"	"hsa:10075; O15029; Q4G2Z2; Q5H961; Q6P4D0; Q7Z6Z7; Q8NG67; Q9BUI0; Q9HCJ4; Q9NSL6; Q9P0A9"	"Antigen processing: Ubiquitination & Proteasome degradation; Neutrophil degranulation"	""	"2"	"0"	"102.6"	"57.8"	"90.1"	"83.9"	"82.6"	"111.8"	"79.3"	"91.5"	"81.4"	"142.0"	"213.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51858"	"Hepatoma-derived growth factor OS=Homo sapiens OX=9606 GN=HDGF PE=1 SV=1"	"0.000"	""	"22"	"4"	"8"	"4"	"240"	"26.8"	"4.73"	"1787.16"	"15.18"	"4"	"4"	"cell organization and biogenesis;signal transduction;other biological processes"	"nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00855"	"3068"	"ENSG00000143321"	"HDGF"	"B3KU21; D3DVC9; hsa:3068; P51858; Q5SZ07; Q5SZ08; Q5SZ09"	"XBP1(S) activates chaperone genes"	"IL-18 signaling pathway"	"2"	"0"	"417.5"	"172.1"	"326.0"	"338.7"	"402.5"	"418.3"	"411.4"	"496.1"	"369.9"	"596.2"	"795.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3Y2"	"Chromatin target of PRMT1 protein OS=Homo sapiens OX=9606 GN=CHTOP PE=1 SV=2"	"0.000"	""	"19"	"4"	"7"	"4"	"248"	"26.4"	"12.23"	"1659.63"	"15.14"	"4"	"3"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf13865"	"26097"	"ENSG00000160679"	"CHTOP"	"D3DV55; hsa:26097; Q0VAQ8; Q2VPI9; Q5T7Y8; Q5T7Y9; Q5T7Z0; Q6NSM4; Q6PB28; Q8WYT9; Q9BUC5; Q9H034; Q9H2L0; Q9Y3Y2"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	""	"3"	"0"	"931.0"	"240.8"	"562.2"	"486.7"	"575.5"	"637.8"	"505.9"	"612.4"	"481.8"	"835.0"	"1667.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P20290"	"Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1"	"0.000"	""	"19"	"4"	"7"	"4"	"206"	"22.2"	"9.38"	"935.66"	"15.12"	"3"	"3"	"transport;developmental processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	""	"Pf01849"	"689"	"ENSG00000145741"	"BTF3"	"A8K510; hsa:689; P20290; Q13893; Q76M56"	""	"Orexin receptor pathway"	"1"	"0"	"514.1"	"190.0"	"400.6"	"381.6"	"458.1"	"803.6"	"925.6"	"1659.3"	"1386.4"	"986.1"	"1093.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15424"	"Scaffold attachment factor B1 OS=Homo sapiens OX=9606 GN=SAFB PE=1 SV=4"	"0.000"	""	"4"	"4"	"10"	"4"	"915"	"102.6"	"5.47"	"1822.50"	"14.98"	"4"	"4"	"cell organization and biogenesis;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf02037"	"6294"	"ENSG00000160633"	"SAFB"	"A0AV56; B7Z5B6; B7ZLP6; F5H0H3; hsa:6294; O60406; Q15424; Q59HH8"	"SUMOylation of transcription cofactors"	"Interleukin-1 (IL-1) structural pathway"	"2"	"0"	"1600.2"	"305.1"	"639.4"	"480.8"	"705.4"	"613.6"	"603.4"	"749.1"	"648.5"	"969.5"	"1636.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P265"	"Disco-interacting protein 2 homolog B OS=Homo sapiens OX=9606 GN=DIP2B PE=1 SV=3"	"0.000"	""	"4"	"5"	"9"	"4"	"1576"	"171.4"	"8.09"	"1220.03"	"14.97"	"4"	"5"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"cytoskeletal activity"	"Pf00501, Pf06464"	"57609"	"ENSG00000066084"	"DIP2B"	"hsa:57609; Q6B011; Q8N1L5; Q8NB38; Q9P265"	""	""	"0"	"1"	"186.1"	"84.7"	"157.0"	"146.1"	"185.6"	"185.6"	"188.1"	"356.9"	"399.0"	"932.2"	"1144.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13148"	"TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1"	"0.000"	""	"14"	"4"	"7"	"4"	"414"	"44.7"	"6.19"	"979.58"	"14.94"	"3"	"4"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf18694"	"23435"	"ENSG00000120948"	"TARDBP"	"A4GUK4; A4GUK5; A4GUK6; B2R629; B4DJ45; E2PU12; hsa:23435; Q13148; Q53H27; Q6FI92; Q96DJ0"	""	"MECP2 and associated Rett syndrome"	"1"	"0"	"248.4"	"75.2"	"195.8"	"167.4"	"206.9"	"226.4"	"174.0"	"220.7"	"173.8"	"393.3"	"704.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NPJ3"	"Acyl-coenzyme A thioesterase 13 OS=Homo sapiens OX=9606 GN=ACOT13 PE=1 SV=1"	"0.000"	""	"25"	"3"	"7"	"3"	"140"	"15.0"	"9.14"	"1325.03"	"14.93"	"2"	"3"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;mitochondrion"	"other molecular function"	"Pf03061"	"55856"	"ENSG00000112304"	"ACOT13"	"F5H2L4; hsa:55856; O95549; Q9NPJ3"	"Mitochondrial Fatty Acid Beta-Oxidation"	""	"1"	"0"	"153.2"	"57.1"	"113.6"	"110.1"	"140.3"	"164.0"	"127.9"	"181.5"	"174.8"	"476.8"	"990.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UIL1"	"Short coiled-coil protein OS=Homo sapiens OX=9606 GN=SCOC PE=1 SV=2"	"0.000"	""	"18"	"2"	"8"	"2"	"159"	"18.0"	"8.85"	"1664.37"	"14.93"	"2"	"2"	"other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus"	""	"Pf10224"	"60592"	"ENSG00000153130"	"SCOC"	"B7WPH7; D3DNY7; E9PB65; hsa:60592; Q6P5T9; Q7L2Y0; Q7Z4P2; Q96JY9; Q9BZB2; Q9UIL1"	"Retrograde transport at the Trans-Golgi-Network"	""	"1"	"0"	"287.6"	"121.2"	"353.3"	"366.7"	"439.0"	"480.8"	"307.7"	"370.1"	"209.9"	"466.6"	"728.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12931"	"Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3"	"0.000"	""	"10"	"6"	"11"	"5"	"704"	"80.1"	"8.21"	"1767.34"	"14.91"	"6"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00183, Pf02518"	"10131"	"ENSG00000126602"	"TRAP1"	"B4DR68; D3DUC8; F5H897; hsa:10131; O43642; O75235; Q12931; Q9UHL5"	"Respiratory electron transport"	"TNF-alpha signaling pathway; Clock-controlled autophagy in bone metabolism"	"3"	"0"	"622.6"	"284.2"	"671.3"	"577.4"	"626.7"	"747.4"	"503.9"	"687.8"	"483.9"	"951.9"	"1227.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3C6"	"Peptidyl-prolyl cis-trans isomerase-like 1 OS=Homo sapiens OX=9606 GN=PPIL1 PE=1 SV=1"	"0.000"	""	"36"	"5"	"10"	"5"	"166"	"18.2"	"7.99"	"1915.77"	"14.91"	"5"	"5"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"nucleus"	"other molecular function"	"Pf00160"	"51645"	"ENSG00000137168"	"PPIL1"	"hsa:51645; O15001; Q5TDC9; Q9Y3C6"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"887.3"	"294.6"	"605.6"	"510.4"	"626.5"	"712.4"	"537.2"	"749.4"	"622.8"	"1223.1"	"2341.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14654"	"Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1"	"0.000"	""	"4"	"6"	"9"	"6"	"1257"	"133.7"	"8.44"	"940.51"	"14.81"	"3"	"6"	"signal transduction"	"plasma membrane;other membranes;cytosol"	"signal transduction activity or receptor binding;other molecular function"	"Pf02174"	"8471"	"ENSG00000133124"	"IRS4"	"hsa:8471; O14654"	"IRS-related events triggered by IGF1R"	"Alzheimer's disease and miRNA effects; Adipogenesis; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Leptin-insulin signaling overlap; Insulin signaling; Alzheimer's disease"	"8"	"0"	"405.6"	"168.7"	"344.8"	"302.4"	"357.0"	"385.5"	"298.3"	"463.7"	"370.1"	"1067.1"	"1865.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14625"	"Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1"	"0.000"	""	"6"	"6"	"11"	"6"	"803"	"92.4"	"4.84"	"1863.00"	"14.78"	"6"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00183, Pf02518"	"7184"	"ENSG00000166598"	"HSP90B1"	"hsa:7184; P14625; Q96A97"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Interleukin-4 and Interleukin-13 signaling; Trafficking and processing of endosomal TLR; Scavenging by Class A Receptors; ATF6 (ATF6-alpha) activates chaperone genes"	"Photodynamic therapy-induced unfolded protein response; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Prion disease pathway; PI3K-Akt signaling pathway; Sudden infant death syndrome (SIDS) susceptibility pathways"	"11"	"0"	"855.3"	"355.5"	"645.9"	"503.4"	"660.0"	"691.3"	"525.7"	"661.5"	"562.2"	"912.0"	"1815.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P15311"	"Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4"	"0.000"	""	"9"	"6"	"9"	"4"	"586"	"69.4"	"6.27"	"1264.56"	"14.78"	"4"	"5"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf00769, Pf09379, Pf09380, Pf20492"	"7430"	"ENSG00000092820"	"EZR"	"E1P5A8; hsa:7430; P15311; P23714; Q4VX75; Q96CU8; Q9NSJ4"	"Recycling pathway of L1; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Netrin-1 signaling"	"Pathogenic Escherichia coli infection; AGE/RAGE pathway; VEGFA-VEGFR2 signaling; 16p11.2 proximal deletion syndrome; CCL18 signaling pathway; Regulation of actin cytoskeleton; GDNF signaling"	"11"	"2"	"727.5"	"268.2"	"542.7"	"431.4"	"570.0"	"545.6"	"471.8"	"643.1"	"550.9"	"2195.5"	"6450.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13112"	"Chromatin assembly factor 1 subunit B OS=Homo sapiens OX=9606 GN=CHAF1B PE=1 SV=1"	"0.000"	""	"7"	"3"	"8"	"3"	"559"	"61.5"	"7.50"	"1396.93"	"14.71"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf00400, Pf15512"	"8208"	"ENSG00000159259"	"CHAF1B"	"hsa:8208; Q13112; Q99548"	""	""	"0"	"0"	"118.3"	"67.5"	"120.2"	"105.4"	"108.5"	"120.6"	"108.6"	"131.4"	"127.8"	"219.9"	"508.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BVJ6"	"U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1"	"0.000"	""	"6"	"4"	"8"	"4"	"771"	"87.9"	"7.87"	"1601.92"	"14.69"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf04615"	"10813"	"ENSG00000156697"	"UTP14A"	"A8K7A3; A8MVQ1; B4DQ08; E9PEL7; hsa:10813; Q5JYF1; Q9BVJ6"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	"117.1"	"58.1"	"142.3"	"119.2"	"124.6"	"144.4"	"108.0"	"155.6"	"128.2"	"252.5"	"418.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95757"	"Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3"	"0.000"	""	"6"	"4"	"7"	"2"	"839"	"94.5"	"5.88"	"1001.28"	"14.69"	"3"	"4"	"protein metabolism;other metabolic processes;stress response"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00012"	"22824"	"ENSG00000164070"	"HSPA4L"	"A2ICT2; hsa:22824; O95757; Q4W5M5; Q8IWA2"	"Regulation of HSF1-mediated heat shock response"	""	"1"	"0"	"57.1"	"30.6"	"47.2"	"55.1"	"53.3"	"56.1"	"46.4"	"52.1"	"59.6"	"95.2"	"163.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVZ3"	"Adaptin ear-binding coat-associated protein 2 OS=Homo sapiens OX=9606 GN=NECAP2 PE=1 SV=1"	"0.000"	""	"15"	"4"	"9"	"3"	"263"	"28.3"	"8.38"	"1838.03"	"14.68"	"4"	"3"	"transport"	"plasma membrane;other membranes"	""	"Pf07933"	"55707"	"ENSG00000157191"	"NECAP2"	"B4DY19; E9PGQ8; hsa:55707; Q5VSU4; Q5VSU5; Q9H7L1; Q9H8L1; Q9NVZ3"	"Cargo recognition for clathrin-mediated endocytosis"	""	"2"	"0"	"112.7"	"45.7"	"96.1"	"94.1"	"98.7"	"168.8"	"290.3"	"1114.6"	"1228.0"	"2152.7"	"2118.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NWB6"	"Arginine and glutamate-rich protein 1 OS=Homo sapiens OX=9606 GN=ARGLU1 PE=1 SV=1"	"0.000"	""	"19"	"7"	"11"	"7"	"273"	"33.2"	"10.35"	"1794.50"	"14.67"	"6"	"5"	""	"cytosol;mitochondrion;nucleus"	""	"Pf15346"	"55082"	"ENSG00000134884"	"ARGLU1"	"B4E0Y3; hsa:55082; Q5T257; Q6IQ34; Q9NWB6"	""	""	"0"	"0"	"1854.3"	"493.6"	"981.5"	"829.8"	"1056.0"	"1182.5"	"932.5"	"1568.0"	"1285.0"	"3152.4"	"5324.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60610"	"Protein diaphanous homolog 1 OS=Homo sapiens OX=9606 GN=DIAPH1 PE=1 SV=2"	"0.000"	""	"6"	"7"	"12"	"7"	"1272"	"141.3"	"5.41"	"2069.04"	"14.56"	"7"	"5"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf02181, Pf06346, Pf06367, Pf06371"	"1729"	"ENSG00000131504"	"DIAPH1"	"A6NF18; B7ZKW2; E9PEZ2; hsa:1729; O60610; Q17RN4; Q59FH8; Q9UC76"	"RHOC GTPase cycle; RHOA GTPase cycle; RHO GTPases Activate Formins; RHOB GTPase cycle; RHOD GTPase cycle; RHOF GTPase cycle; Neutrophil degranulation; ERBB2 Regulates Cell Motility"	"Microtubule cytoskeleton regulation; AGE/RAGE pathway; Focal adhesion; Type 2 papillary renal cell carcinoma; Regulation of actin cytoskeleton; G13 signaling pathway"	"14"	"0"	"474.5"	"256.5"	"546.9"	"465.6"	"472.8"	"590.6"	"424.0"	"547.3"	"422.7"	"783.2"	"1201.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P12532"	"Creatine kinase U-type, mitochondrial OS=Homo sapiens OX=9606 GN=CKMT1A PE=1 SV=1"	"0.000"	""	"6"	"2"	"7"	"2"	"417"	"47.0"	"8.34"	"1434.83"	"14.55"	"2"	"2"	"other metabolic processes"	"other membranes;mitochondrion"	"kinase activity;other molecular function"	"Pf00217, Pf02807"	"1159; 548596"	"ENSG00000223572; ENSG00000237289"	"CKMT1A; CKMT1B"	"B4DIT8; B7ZA09; hsa:1159; hsa:548596; P12532; Q0VAM3; Q32NF6; Q53FC4"	"Creatine metabolism"	""	"1"	"0"	"394.9"	"148.9"	"282.1"	"228.1"	"312.4"	"315.0"	"252.7"	"381.7"	"306.6"	"564.7"	"775.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UPT8"	"Zinc finger CCCH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=ZC3H4 PE=1 SV=3"	"0.000"	""	"5"	"4"	"5"	"4"	"1303"	"140.2"	"6.27"	"314.98"	"14.48"	"1"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00642, Pf14608, Pf18044"	"23211"	"ENSG00000130749"	"ZC3H4"	"hsa:23211; Q9UPT8; Q9Y420"	""	""	"0"	"0"	"335.8"	"154.6"	"291.4"	"235.5"	"275.7"	"300.7"	"222.8"	"298.2"	"200.4"	"513.7"	"992.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P04637"	"Cellular tumor antigen p53 OS=Homo sapiens OX=9606 GN=TP53 PE=1 SV=4"	"0.000"	""	"13"	"5"	"9"	"5"	"393"	"43.6"	"6.79"	"2034.39"	"14.47"	"5"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00870, Pf07710, Pf08563, Pf18521"	"7157"	"ENSG00000141510"	"TP53"	"hsa:7157; P04637; Q15086; Q15087; Q15088; Q16535; Q16807; Q16808; Q16809; Q16810; Q16811; Q16848; Q2XN98; Q3LRW1; Q3LRW2; Q3LRW3; Q3LRW4; Q3LRW5; Q86UG1; Q8J016; Q99659; Q9BTM4; Q9HAQ8; Q9NP68; Q9NPJ2; Q9NZD0; Q9UBI2; Q9UQ61"	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; TP53 Regulates Transcription of DNA Repair Genes; TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest; Autodegradation of the E3 ubiquitin ligase COP1; Ub-specific processing proteases; The role of GTSE1 in G2/M progression after G2 checkpoint; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain; Regulation of TP53 Degradation; TP53 Regulates Transcription of Death Receptors and Ligands; Oxidative Stress Induced Senescence; Regulation of PTEN gene transcription; Regulation of TP53 Activity through Phosphorylation; TP53 Regulates Metabolic Genes; Association of TriC/CCT with target proteins during biosynthesis; Interleukin-4 and Interleukin-13 signaling; Pre-NOTCH Transcription and Translation; Oncogene Induced Senescence; Transcriptional Regulation by VENTX; Factors involved in megakaryocyte development and platelet production; TP53 Regulates Transcription of Caspase Activators and Caspases; Regulation of TP53 Activity through Methylation; G2/M DNA damage checkpoint; Regulation of NF-kappa B signaling; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Activation of PUMA and translocation to mitochondria; TP53 Regulates Transcription of Genes Involved in Cytochrome C Release; TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain; Regulation of TP53 Activity through Association with Co-factors; Ovarian tumor domain proteases; Pyroptosis; SUMOylation of transcription factors; Regulation of TP53 Expression; RUNX3 regulates CDKN1A transcription; Activation of NOXA and translocation to mitochondria; Formation of Senescence-Associated Heterochromatin Foci (SAHF); PI5P Regulates TP53 Acetylation; Transcriptional  activation of  cell cycle inhibitor p21 ; Loss of function of TP53 in cancer due to loss of tetramerization ability"	"AMP-activated protein kinase signaling; miRNA regulation of DNA damage response; miRNAs involved in DNA damage response; Fluoropyrimidine activity; TP53 network; Folate metabolism; Apoptosis modulation and signaling; Cell cycle; Metastatic brain tumor; Glioblastoma signaling pathways; Gastric cancer network 2; Oncostatin M signaling pathway; Spinal cord injury; Retinoblastoma gene in cancer; Amyotrophic lateral sclerosis (ALS); ATM signaling pathway; Apoptosis; Mammary gland development pathway - Involution (Stage 4 of 4); Bladder cancer; Copper homeostasis; RAC1/PAK1/p38/MMP2 pathway; Photodynamic therapy-induced HIF-1 survival signaling; Hepatitis C and hepatocellular carcinoma; Pathways affected in adenoid cystic carcinoma; lncRNA-mediated mechanisms of therapeutic resistance; MAPK signaling pathway; miRNA regulation of p53 pathway in prostate cancer; Wnt signaling pathway and pluripotency; Endometrial cancer; PI3K-Akt signaling pathway; Caloric restriction and aging; Chromosomal and microsatellite instability in colorectal cancer ; Epithelial to mesenchymal transition in colorectal cancer; Non-small cell lung cancer; Breast cancer pathway; Pancreatic adenocarcinoma pathway; Ultraconserved region 339 modulation of tumor suppressor microRNAs in cancer; Ferroptosis; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; MicroRNA network associated with chronic lymphocytic leukemia; G1 to S cell cycle control; Measles virus infection; 22q11.2 copy number variation syndrome; Small cell lung cancer; Head and neck squamous cell carcinoma; Melanoma; Thyroid hormones production and peripheral downstream signaling effects; Netrin-UNC5B signaling pathway; IL-18 signaling pathway; Unfolded protein response; 16p11.2 proximal deletion syndrome; Pentose phosphate pathway in senescent cells; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Glycolysis in senescence; TCA cycle in senescence; Pleural mesothelioma; Lipid metabolism in senescent cells; DYRK1A involvement regarding cell proliferation in brain development; 2q37 copy number variation syndrome; Autophagy in pancreatic ductal adenocarcinoma; 11p11.2 copy number variation syndrome ; A network map of Macrophage-stimulating protein (MSP) signaling; ErbB signaling pathway; DNA damage response; DNA damage response (only ATM dependent)"	"107"	"0"	"474.9"	"174.6"	"431.4"	"331.6"	"364.6"	"453.5"	"316.0"	"474.9"	"352.5"	"685.2"	"1107.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P78356"	"Phosphatidylinositol 5-phosphate 4-kinase type-2 beta OS=Homo sapiens OX=9606 GN=PIP4K2B PE=1 SV=1"	"0.000"	""	"10"	"4"	"8"	"4"	"416"	"47.3"	"7.33"	"1361.82"	"14.47"	"4"	"4"	"cell organization and biogenesis;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle"	"kinase activity;other molecular function"	"Pf01504"	"8396"	"ENSG00000276293; ENSG00000277292"	"PIP4K2B"	"hsa:8396; P78356; Q5U0E8; Q8TBP2"	"Synthesis of PIPs at the plasma membrane; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; PI5P Regulates TP53 Acetylation; Synthesis of PIPs in the nucleus"	"Regulation of actin cytoskeleton; 17q12 copy number variation syndrome"	"6"	"0"	"139.5"	"76.9"	"149.6"	"147.4"	"159.9"	"249.0"	"344.0"	"699.5"	"944.5"	"2266.8"	"1810.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P16403"	"Histone H1.2 OS=Homo sapiens OX=9606 GN=H1-2 PE=1 SV=2"	"0.000"	""	"23"	"5"	"11"	"5"	"213"	"21.4"	"10.93"	"2546.68"	"14.39"	"5"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00538"	"3006"	"ENSG00000187837"	"H1-2"	"A8K4I2; hsa:3006; P16403"	"Formation of Senescence-Associated Heterochromatin Foci (SAHF); Apoptosis induced DNA fragmentation"	""	"2"	"0"	"1694.9"	"913.6"	"1326.9"	"1047.7"	"1188.7"	"1481.5"	"1161.5"	"1551.8"	"1332.8"	"1927.6"	"2330.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61218"	"DNA-directed RNA polymerases I, II, and III subunit RPABC2 OS=Homo sapiens OX=9606 GN=POLR2F PE=1 SV=1"	"0.000"	""	"33"	"3"	"5"	"3"	"127"	"14.5"	"4.22"	"526.11"	"14.37"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01192"	"5435"	"ENSG00000100142"	"POLR2F"	"hsa:5435; P41584; P61218; Q6IAY3"	"mRNA Splicing - Major Pathway; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; B-WICH complex positively regulates rRNA expression; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"56"	"0"	"261.5"	"108.1"	"258.0"	"211.9"	"255.5"	"300.0"	"269.3"	"361.7"	"487.7"	"1327.1"	"2244.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46063"	"ATP-dependent DNA helicase Q1 OS=Homo sapiens OX=9606 GN=RECQL PE=1 SV=3"	"0.000"	""	"7"	"4"	"8"	"4"	"649"	"73.4"	"7.88"	"1356.41"	"14.34"	"4"	"4"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf16124"	"5965"	"ENSG00000004700"	"RECQL"	"A8K6G2; hsa:5965; P46063"	""	"Progeria-associated lipodystrophy"	"1"	"0"	"229.1"	"107.3"	"209.4"	"205.0"	"199.3"	"274.0"	"181.6"	"231.4"	"195.9"	"262.4"	"562.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P04899"	"Guanine nucleotide-binding protein G(i) subunit alpha-2 OS=Homo sapiens OX=9606 GN=GNAI2 PE=1 SV=3"	"0.000"	""	"11"	"4"	"10"	"1"	"355"	"40.4"	"5.54"	"1360.71"	"14.26"	"4"	"4"	"cell-cell signaling;cell cycle OR cell proliferation;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00503"	"2771"	"ENSG00000114353"	"GNAI2"	"B3KTZ0; B4DYA0; B4E2X5; hsa:2771; P04899; Q6B6N3; Q8IZ71"	"G alpha (i) signalling events; G alpha (z) signalling events; Adenylate cyclase inhibitory pathway; ADP signalling through P2Y purinoceptor 12; Extra-nuclear estrogen signaling; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; Adrenaline,noradrenaline inhibits insulin secretion"	"Thyroid stimulating hormone (TSH) signaling pathway; Corticotropin-releasing hormone signaling pathway; S1P receptor signal transduction; Complement system; G protein signaling pathways; Chemokine signaling pathway; Hippo signaling regulation pathways; Purinergic signaling; Opioid receptor pathways; Calcium regulation in cardiac cells; 5q35 copy number variation; Serotonin HTR1 group and FOS pathway"	"22"	"0"	"47.8"	"21.0"	"45.6"	"31.8"	"42.2"	"41.4"	"37.8"	"46.2"	"45.6"	"104.9"	"249.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13098"	"COP9 signalosome complex subunit 1 OS=Homo sapiens OX=9606 GN=GPS1 PE=1 SV=4"	"0.000"	""	"9"	"3"	"6"	"3"	"491"	"55.5"	"6.74"	"1598.96"	"14.18"	"3"	"3"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf01399, Pf10602"	"2873"	"ENSG00000169727"	"GPS1"	"hsa:2873; Q13098; Q8NA10; Q9BWL1"	"Neddylation; Cargo recognition for clathrin-mediated endocytosis; Formation of TC-NER Pre-Incision Complex; RHOBTB1 GTPase cycle; DNA Damage Recognition in GG-NER"	""	"5"	"0"	"38.3"	"19.5"	"44.8"	"39.0"	"35.3"	"80.8"	"109.0"	"199.4"	"226.8"	"454.6"	"1306.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P28331"	"NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS1 PE=1 SV=3"	"0.000"	""	"10"	"6"	"11"	"6"	"727"	"79.4"	"6.23"	"1778.05"	"14.16"	"6"	"5"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00384, Pf09326, Pf10588, Pf13510"	"4719"	"ENSG00000023228; ENSG00000283447"	"NDUFS1"	"B4DIN9; B4DJA0; B4DPG1; B4DUC1; E7ENF3; hsa:4719; P28331; Q53TR8; Q8N1C4; Q8TCC9"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"5"	"0"	"256.3"	"100.6"	"170.2"	"129.3"	"193.1"	"217.5"	"181.0"	"241.8"	"212.7"	"484.7"	"933.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00425"	"Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2"	"0.000"	""	"8"	"4"	"9"	"3"	"579"	"63.7"	"8.87"	"1798.26"	"14.13"	"4"	"3"	"protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf00076"	"10643"	"ENSG00000136231"	"IGF2BP3"	"A0A4Z5; hsa:10643; O00425; Q63HM0; Q6MZZ2; Q86VB1"	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"	""	"1"	"0"	"446.8"	"122.3"	"280.0"	"233.9"	"292.0"	"290.8"	"219.8"	"311.7"	"238.9"	"486.2"	"981.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UII2"	"ATPase inhibitor, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5IF1 PE=1 SV=1"	"0.000"	""	"24"	"3"	"10"	"3"	"106"	"12.2"	"9.35"	"1616.55"	"14.13"	"3"	"3"	"cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"mitochondrion;other cell component"	"enzyme regulator activity;other molecular function"	"Pf04568"	"93974"	"ENSG00000130770; ENSG00000285390"	"ATP5IF1"	"hsa:93974; Q5JXL8; Q6IAQ7; Q9BSL9; Q9UII2"	""	"Electron transport chain: OXPHOS system in mitochondria"	"1"	"0"	"1553.9"	"808.5"	"1505.3"	"1426.7"	"1538.1"	"1727.7"	"1350.4"	"1666.6"	"1200.4"	"2205.3"	"3018.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBL3"	"Set1/Ash2 histone methyltransferase complex subunit ASH2 OS=Homo sapiens OX=9606 GN=ASH2L PE=1 SV=1"	"0.000"	""	"7"	"3"	"5"	"3"	"628"	"68.7"	"5.69"	"921.25"	"14.10"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00622"	"9070"	"ENSG00000129691"	"ASH2L"	"A8K7C3; D3DSW9; hsa:9070; O60659; O60660; Q96B62; Q9UBL3"	"Deactivation of the beta-catenin transactivating complex; Formation of the beta-catenin:TCF transactivating complex; Activation of anterior HOX genes in hindbrain development during early embryogenesis; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Formation of WDR5-containing histone-modifying complexes; PKMTs methylate histone lysines"	"Kleefstra syndrome"	"7"	"0"	"174.5"	"64.8"	"178.4"	"136.6"	"163.4"	"184.8"	"165.8"	"218.1"	"170.0"	"362.5"	"606.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NDT2"	"Putative RNA-binding protein 15B OS=Homo sapiens OX=9606 GN=RBM15B PE=1 SV=3"	"0.000"	""	"5"	"3"	"8"	"2"	"890"	"97.1"	"9.85"	"1003.46"	"14.09"	"2"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf07744"	"29890"	"ENSG00000259956"	"RBM15B"	"A4QPG7; hsa:29890; Q6QE19; Q8NDT2; Q9BV96"	""	""	"0"	"0"	"27.1"	"9.4"	"19.4"	"14.7"	"26.5"	"26.0"	"17.7"	"38.8"	"45.5"	"156.0"	"219.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96CT7"	"Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1"	"0.000"	""	"22"	"4"	"6"	"4"	"223"	"25.8"	"9.54"	"684.67"	"14.07"	"2"	"4"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf06244"	"115098"	"ENSG00000007080"	"CCDC124"	"hsa:115098; Q96CT7"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"306.0"	"127.8"	"268.4"	"247.2"	"260.2"	"310.1"	"208.3"	"308.1"	"255.2"	"1027.1"	"2348.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H2K8"	"Serine/threonine-protein kinase TAO3 OS=Homo sapiens OX=9606 GN=TAOK3 PE=1 SV=2"	"0.000"	""	"6"	"6"	"10"	"2"	"898"	"105.3"	"7.30"	"1631.01"	"14.05"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069"	"51347"	"ENSG00000135090"	"TAOK3"	"hsa:51347; Q658N1; Q8IUM4; Q9H2K8; Q9HC79; Q9NZM9; Q9UHG7"	"RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle"	"MAPK signaling pathway"	"4"	"0"	"29.9"	"8.5"	"24.5"	"16.5"	"25.2"	"26.4"	"35.4"	"57.2"	"82.6"	"269.8"	"615.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y376"	"Calcium-binding protein 39 OS=Homo sapiens OX=9606 GN=CAB39 PE=1 SV=1"	"0.000"	""	"12"	"5"	"10"	"5"	"341"	"39.8"	"6.89"	"1615.99"	"14.04"	"5"	"5"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;other molecular function"	"Pf08569"	"51719"	"ENSG00000135932"	"CAB39"	"A8K8L7; hsa:51719; Q9Y376"	"Neutrophil degranulation; Energy dependent regulation of mTOR by LKB1-AMPK"	"AMP-activated protein kinase signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Endochondral ossification; Endochondral ossification with skeletal dysplasias"	"6"	"0"	"93.9"	"39.2"	"85.5"	"86.4"	"108.4"	"130.4"	"131.0"	"222.4"	"282.1"	"594.8"	"818.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14168"	"MAGUK p55 subfamily member 2 OS=Homo sapiens OX=9606 GN=MPP2 PE=1 SV=3"	"0.000"	""	"9"	"4"	"8"	"3"	"576"	"64.5"	"6.77"	"1656.85"	"13.96"	"4"	"4"	"cell-cell signaling;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	""	"Pf00595, Pf00625, Pf02828, Pf07653"	"4355"	"ENSG00000108852"	"MPP2"	"B4DGE9; B4DRJ0; B7Z3G8; E7EV80; E7EV91; E7EX01; hsa:4355; Q14168; Q53ES9; Q5CZB9; Q9BQJ2"	""	""	"0"	"0"	"83.0"	"49.1"	"69.9"	"56.3"	"65.9"	"77.4"	"74.7"	"86.8"	"108.0"	"207.1"	"399.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13263"	"Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5"	"0.000"	""	"5"	"4"	"8"	"4"	"835"	"88.5"	"5.77"	"1549.38"	"13.96"	"4"	"4"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00628, Pf00643, Pf14634"	"10155"	"ENSG00000130726"	"TRIM28"	"hsa:10155; O00677; Q13263; Q7Z632; Q93040; Q96IM1"	"Generic Transcription Pathway; HCMV Early Events; SUMOylation of transcription cofactors"	"Corticotropin-releasing hormone signaling pathway; Mesodermal commitment pathway; ATM signaling in development and disease"	"6"	"0"	"486.4"	"154.4"	"285.0"	"231.1"	"303.0"	"309.1"	"248.1"	"317.2"	"288.1"	"444.0"	"775.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15056"	"Eukaryotic translation initiation factor 4H OS=Homo sapiens OX=9606 GN=EIF4H PE=1 SV=5"	"0.000"	""	"29"	"5"	"8"	"5"	"248"	"27.4"	"7.23"	"1293.12"	"13.94"	"4"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"7458"	"ENSG00000106682"	"EIF4H"	"A8K3R1; D3DXF6; D3DXF8; hsa:7458; Q15056"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Translation initiation complex formation; Ribosomal scanning and start codon recognition"	"Translation factors; 7q11.23 copy number variation syndrome"	"7"	"0"	"498.9"	"259.4"	"419.0"	"408.8"	"450.2"	"503.2"	"455.7"	"518.9"	"442.0"	"656.5"	"1111.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P258"	"Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2"	"0.000"	""	"11"	"6"	"11"	"6"	"522"	"56.0"	"8.78"	"2129.84"	"13.93"	"6"	"3"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00415"	"55920"	"ENSG00000179051; ENSG00000281540"	"RCC2"	"hsa:55920; Q8IVL9; Q9BSN6; Q9NPV8; Q9P258"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	""	"6"	"0"	"995.3"	"452.4"	"768.5"	"678.1"	"714.5"	"896.6"	"793.3"	"1353.9"	"1199.6"	"1456.1"	"1475.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BWJ5"	"Splicing factor 3B subunit 5 OS=Homo sapiens OX=9606 GN=SF3B5 PE=1 SV=1"	"0.000"	""	"37"	"3"	"7"	"3"	"86"	"10.1"	"6.35"	"1004.09"	"13.93"	"2"	"3"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf07189"	"83443"	"ENSG00000169976"	"SF3B5"	"B2R568; hsa:83443; Q7RTV1; Q9BWJ5"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"mRNA processing"	"3"	"0"	"304.3"	"114.4"	"279.2"	"237.6"	"241.7"	"295.3"	"241.1"	"292.3"	"274.6"	"469.2"	"683.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H4G0"	"Band 4.1-like protein 1 OS=Homo sapiens OX=9606 GN=EPB41L1 PE=1 SV=2"	"0.000"	""	"6"	"4"	"7"	"4"	"881"	"98.4"	"5.62"	"1933.84"	"13.84"	"4"	"3"	"cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;cytoskeleton"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf04382, Pf05902, Pf08736, Pf09379, Pf09380"	"2036"	"ENSG00000088367"	"EPB41L1"	"hsa:2036; O15046; Q4VXM6; Q4VXM7; Q4VXM8; Q4VXN4; Q6ZT61; Q8IUU7; Q96CV5; Q96L65; Q9H4G0"	"Trafficking of AMPA receptors; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Neurexins and neuroligins"	"Splicing factor NOVA regulated synaptic proteins"	"5"	"0"	"125.6"	"57.8"	"110.3"	"96.8"	"118.5"	"137.4"	"99.5"	"173.9"	"393.5"	"1610.6"	"1625.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92796"	"Disks large homolog 3 OS=Homo sapiens OX=9606 GN=DLG3 PE=1 SV=2"	"0.000"	""	"6"	"3"	"6"	"3"	"817"	"90.3"	"7.03"	"1349.95"	"13.81"	"3"	"3"	"cell-cell signaling;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00018, Pf00595, Pf00625, Pf10600"	"1741"	"ENSG00000082458"	"DLG3"	"B4E0H1; D3DVU5; hsa:1741; Q5JUW6; Q5JUW7; Q92796; Q9ULI8"	"Activation of Ca-permeable Kainate Receptor; Assembly and cell surface presentation of NMDA receptors; RAF/MAP kinase cascade; Neurexins and neuroligins; Ras activation upon Ca2+ influx through NMDA receptor; Unblocking of NMDA receptors, glutamate binding and activation; Synaptic adhesion-like molecules; Negative regulation of NMDA receptor-mediated neuronal transmission; Long-term potentiation; NrCAM interactions"	""	"10"	"0"	"61.8"	"32.1"	"61.4"	"47.8"	"64.9"	"66.6"	"57.9"	"88.3"	"99.2"	"254.7"	"498.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15007"	"Pre-mRNA-splicing regulator WTAP OS=Homo sapiens OX=9606 GN=WTAP PE=1 SV=2"	"0.000"	""	"8"	"2"	"6"	"2"	"396"	"44.2"	"5.19"	"1300.71"	"13.79"	"2"	"2"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf17098"	"9589"	"ENSG00000146457"	"WTAP"	"hsa:9589; Q15007; Q5TCL8; Q5TCL9; Q96T28; Q9BYJ7; Q9H4E2"	"Processing of Capped Intron-Containing Pre-mRNA"	""	"1"	"0"	"92.0"	"24.5"	"75.8"	"52.1"	"70.8"	"72.0"	"60.3"	"81.7"	"70.0"	"126.9"	"183.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P54886"	"Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2"	"0.000"	""	"6"	"4"	"8"	"4"	"795"	"87.2"	"7.12"	"1380.82"	"13.77"	"4"	"4"	"other metabolic processes"	"other membranes;mitochondrion"	"kinase activity;other molecular function"	"Pf00171, Pf00696"	"5832"	"ENSG00000059573"	"ALDH18A1"	"B2R5Q4; B7Z350; B7Z5X8; B7ZLP1; D3DR44; hsa:5832; O95952; P54886; Q3KQU2; Q5T566; Q5T567; Q9UM72"	""	"Amino acid metabolism"	"1"	"0"	"300.0"	"138.5"	"311.8"	"262.8"	"260.4"	"342.5"	"232.6"	"287.2"	"232.4"	"442.4"	"599.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NYL9"	"Tropomodulin-3 OS=Homo sapiens OX=9606 GN=TMOD3 PE=1 SV=1"	"0.000"	""	"14"	"3"	"6"	"3"	"352"	"39.6"	"5.19"	"1326.28"	"13.76"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton"	"cytoskeletal activity"	"Pf03250"	"29766"	"ENSG00000138594"	"TMOD3"	"B2R6G7; hsa:29766; Q9NT43; Q9NYL9; Q9NZR0"	"RND3 GTPase cycle; Striated Muscle Contraction; RHOBTB2 GTPase cycle"	"VEGFA-VEGFR2 signaling"	"4"	"0"	"200.2"	"110.5"	"189.4"	"161.3"	"198.3"	"215.3"	"163.9"	"197.4"	"151.0"	"345.1"	"608.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49006"	"MARCKS-related protein OS=Homo sapiens OX=9606 GN=MARCKSL1 PE=1 SV=2"	"0.000"	""	"18"	"3"	"8"	"3"	"195"	"19.5"	"4.67"	"1322.94"	"13.72"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02063"	"65108"	"ENSG00000175130"	"MARCKSL1"	"D3DPQ0; hsa:65108; P49006; Q5TEE6; Q6NXS5"	""	""	"0"	"0"	"741.8"	"295.1"	"544.6"	"512.0"	"616.0"	"628.3"	"629.4"	"785.6"	"597.3"	"1014.8"	"2100.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5T9A4"	"ATPase family AAA domain-containing protein 3B OS=Homo sapiens OX=9606 GN=ATAD3B PE=1 SV=1"	"0.000"	""	"8"	"4"	"6"	"1"	"648"	"72.5"	"9.20"	"673.55"	"13.64"	"2"	"4"	"cell organization and biogenesis"	"plasma membrane;other membranes;mitochondrion"	"other molecular function"	"Pf00004, Pf12037"	"83858"	"ENSG00000160072"	"ATAD3B"	"A8K3H1; hsa:83858; Q5T9A4; Q6ZRB5; Q9BUK4; Q9ULE7"	"Neutrophil degranulation"	"1p36 copy number variation syndrome"	"2"	"0"	"12.6"	"8.3"	"7.5"	"8.0"	"8.1"	"8.4"	"11.6"	"10.4"	"13.8"	"19.8"	"39.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULC4"	"Malignant T-cell-amplified sequence 1 OS=Homo sapiens OX=9606 GN=MCTS1 PE=1 SV=1"	"0.000"	""	"33"	"4"	"8"	"4"	"181"	"20.5"	"8.82"	"1578.54"	"13.62"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"other cell component"	"nucleic acid binding activity"	"Pf01472, Pf17832"	"28985"	"ENSG00000232119; ENSG00000288295"	"MCTS1"	"B4DGY2; hsa:28985; Q502X6; Q9ULC4"	""	""	"0"	"0"	"120.7"	"62.4"	"115.9"	"100.6"	"129.7"	"149.3"	"122.7"	"135.9"	"133.8"	"292.9"	"803.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IZP0"	"Abl interactor 1 OS=Homo sapiens OX=9606 GN=ABI1 PE=1 SV=4"	"0.000"	""	"13"	"4"	"7"	"4"	"508"	"55.0"	"7.06"	"1932.43"	"13.62"	"4"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00018, Pf07815"	"10006"	"ENSG00000136754"	"ABI1"	"A9Z1Y6; B3KX62; B4DQ58; H7BXI6; hsa:10006; O15147; O76049; O95060; Q5T2R3; Q5T2R4; Q5T2R6; Q5T2R7; Q5T2R9; Q5W070; Q5W072; Q8IZP0; Q8TB63; Q96S81; Q9NXZ9; Q9NYB8"	"RAC2 GTPase cycle; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RAC1 GTPase cycle; RHO GTPases Activate WASPs and WAVEs; RAC3 GTPase cycle; VEGFA-VEGFR2 Pathway"	"EGF/EGFR signaling pathway"	"8"	"0"	"262.9"	"107.6"	"241.4"	"201.8"	"228.4"	"262.1"	"184.8"	"338.8"	"257.0"	"551.4"	"1020.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86U42"	"Polyadenylate-binding protein 2 OS=Homo sapiens OX=9606 GN=PABPN1 PE=1 SV=3"	"0.000"	""	"12"	"4"	"10"	"4"	"306"	"32.7"	"5.06"	"1456.02"	"13.60"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;transport;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"8106"	"ENSG00000100836"	"PABPN1"	"D3DS49; hsa:8106; O43484; Q86U42"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; Inhibition of Host mRNA Processing and RNA Silencing"	"mRNA processing"	"6"	"0"	"1198.6"	"293.5"	"660.2"	"562.2"	"689.8"	"755.1"	"580.1"	"751.1"	"618.9"	"1161.0"	"2054.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60841"	"Eukaryotic translation initiation factor 5B OS=Homo sapiens OX=9606 GN=EIF5B PE=1 SV=4"	"0.000"	""	"4"	"3"	"5"	"3"	"1220"	"138.7"	"5.49"	"962.49"	"13.53"	"2"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03144, Pf11987"	"9669"	"ENSG00000158417"	"EIF5B"	"hsa:9669; O60841; O95805; Q53RV7; Q53SI8; Q9UF81; Q9UMN7"	"GTP hydrolysis and joining of the 60S ribosomal subunit"	"Translation factors; Ciliary landscape"	"3"	"0"	"115.9"	"41.6"	"100.3"	"75.3"	"84.2"	"117.0"	"110.8"	"162.3"	"166.8"	"312.1"	"556.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53680"	"AP-2 complex subunit sigma OS=Homo sapiens OX=9606 GN=AP2S1 PE=1 SV=2"	"0.000"	""	"27"	"4"	"9"	"4"	"142"	"17.0"	"6.18"	"1166.26"	"13.52"	"4"	"4"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01217"	"1175"	"ENSG00000042753"	"AP2S1"	"B2R4Z4; hsa:1175; O75977; P53680; Q6PK67"	"Cargo recognition for clathrin-mediated endocytosis; LDL clearance; Recycling pathway of L1; MHC class II antigen presentation; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; Retrograde neurotrophin signalling; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation; Potential therapeutics for SARS; Nef Mediated CD4 Down-regulation; Nef Mediated CD8 Down-regulation"	"Synaptic vesicle pathway; VEGFA-VEGFR2 signaling; GABA receptor signaling; EGF/EGFR signaling pathway; Fragile X syndrome"	"18"	"0"	"168.6"	"78.7"	"143.9"	"124.1"	"137.1"	"199.6"	"269.9"	"830.6"	"1067.6"	"1939.8"	"1724.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P43250"	"G protein-coupled receptor kinase 6 OS=Homo sapiens OX=9606 GN=GRK6 PE=1 SV=2"	"0.000"	""	"8"	"3"	"6"	"3"	"576"	"65.9"	"8.00"	"1213.98"	"13.50"	"3"	"3"	"cell-cell signaling;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00615"	"2870"	"ENSG00000198055"	"GRK6"	"hsa:2870; O60541; P43250; Q13652"	"G alpha (s) signalling events"	"Follicle stimulating hormone (FSH) signaling pathway; Corticotropin-releasing hormone signaling pathway; Myometrial relaxation and contraction pathways; Chemokine signaling pathway; Calcium regulation in cardiac cells; 5q35 copy number variation"	"7"	"0"	"100.4"	"46.1"	"93.9"	"89.6"	"90.3"	"103.9"	"88.8"	"171.5"	"243.2"	"842.2"	"899.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08754"	"Guanine nucleotide-binding protein G(i) subunit alpha OS=Homo sapiens OX=9606 GN=GNAI3 PE=1 SV=3"	"0.000"	""	"11"	"4"	"10"	"1"	"354"	"40.5"	"5.69"	"1330.61"	"13.45"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00503"	"2773"	"ENSG00000065135"	"GNAI3"	"hsa:2773; P08754; P17539; Q5TZX1"	"G alpha (i) signalling events; G alpha (z) signalling events; Adenylate cyclase inhibitory pathway; ADP signalling through P2Y purinoceptor 12; Extra-nuclear estrogen signaling; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production"	"Thyroid stimulating hormone (TSH) signaling pathway; S1P receptor signal transduction; Complement system; G protein signaling pathways; Chemokine signaling pathway; Hippo signaling regulation pathways; Purinergic signaling; Calcium regulation in cardiac cells; 5q35 copy number variation; Serotonin HTR1 group and FOS pathway"	"18"	"2"	"663.0"	"222.8"	"431.3"	"421.3"	"464.6"	"511.5"	"450.5"	"636.0"	"479.7"	"988.4"	"1939.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60306"	"RNA helicase aquarius OS=Homo sapiens OX=9606 GN=AQR PE=1 SV=4"	"0.000"	""	"3"	"4"	"9"	"4"	"1485"	"171.2"	"6.37"	"1917.13"	"13.44"	"4"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13086, Pf13087, Pf16399"	"9716"	"ENSG00000021776"	"AQR"	"A0JP17; A5YKK3; hsa:9716; O60306; Q2YDX9; Q6IRU8; Q6PIC8"	"mRNA Splicing - Major Pathway; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	""	"5"	"0"	"132.8"	"54.9"	"87.2"	"77.8"	"95.8"	"95.9"	"94.1"	"108.5"	"106.0"	"192.7"	"419.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6WKZ4"	"Rab11 family-interacting protein 1 OS=Homo sapiens OX=9606 GN=RAB11FIP1 PE=1 SV=3"	"0.000"	""	"5"	"5"	"8"	"5"	"1283"	"137.1"	"5.43"	"1616.91"	"13.44"	"4"	"4"	"transport;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00168, Pf09457"	"80223"	"ENSG00000156675"	"RAB11FIP1"	"hsa:80223; J3KNP0; Q307T1; Q6AZK4; Q6WKZ2; Q6WKZ4; Q6WKZ6; Q86YV4; Q8TDL1; Q9H642"	""	""	"0"	"0"	"156.9"	"68.1"	"123.0"	"132.5"	"138.1"	"244.0"	"326.2"	"632.7"	"776.1"	"1623.5"	"2009.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IWX8"	"Calcium homeostasis endoplasmic reticulum protein OS=Homo sapiens OX=9606 GN=CHERP PE=1 SV=3"	"0.000"	""	"4"	"5"	"10"	"5"	"916"	"103.6"	"9.04"	"1426.07"	"13.43"	"5"	"5"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf01585, Pf01805, Pf04818"	"10523"	"ENSG00000085872"	"CHERP"	"hsa:10523; O00302; Q4G0Y5; Q8IWX8; Q8WU30; Q99492"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"875.7"	"345.9"	"630.9"	"571.4"	"628.2"	"721.1"	"568.6"	"731.8"	"568.7"	"815.5"	"1343.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14174"	"Macrophage migration inhibitory factor OS=Homo sapiens OX=9606 GN=MIF PE=1 SV=4"	"0.000"	""	"11"	"2"	"8"	"2"	"115"	"12.5"	"7.88"	"1427.18"	"13.42"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01187"	"4282"	"ENSG00000240972; ENSG00000276701"	"MIF"	"A5Z1R8; B2R4S3; hsa:4282; P14174; Q2V4Y5; Q6FHV0"	"Neutrophil degranulation; Cell surface interactions at the vascular wall; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"Adipogenesis; Spinal cord injury"	"5"	"0"	"724.0"	"137.9"	"407.6"	"171.9"	"412.3"	"272.2"	"398.5"	"388.5"	"566.1"	"648.1"	"1503.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14684"	"Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3"	"0.000"	""	"9"	"5"	"7"	"5"	"758"	"84.4"	"9.76"	"1304.13"	"13.41"	"4"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf05997"	"23076"	"ENSG00000160208"	"RRP1B"	"hsa:23076; Q14684; Q8TBZ4"	""	""	"0"	"0"	"352.2"	"160.0"	"315.4"	"289.4"	"305.0"	"339.2"	"297.7"	"424.2"	"338.2"	"824.1"	"1679.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99496"	"E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1"	"0.000"	""	"14"	"4"	"8"	"3"	"336"	"37.6"	"6.84"	"1161.28"	"13.40"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf13923, Pf16207"	"6045"	"ENSG00000121481"	"RNF2"	"B2RBS7; B3KRH1; hsa:6045; Q5TEN1; Q5TEN2; Q99496"	"Transcriptional Regulation by E2F6; Oxidative Stress Induced Senescence; Regulation of PTEN gene transcription; SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"	"FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; Pleural mesothelioma"	"11"	"1"	"271.7"	"145.1"	"247.0"	"228.9"	"279.3"	"351.4"	"293.3"	"405.2"	"323.4"	"470.1"	"706.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BTD8"	"RNA-binding protein 42 OS=Homo sapiens OX=9606 GN=RBM42 PE=1 SV=1"	"0.000"	""	"13"	"5"	"7"	"5"	"480"	"50.4"	"9.63"	"896.94"	"13.39"	"3"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"79171"	"ENSG00000126254"	"RBM42"	"hsa:79171; O00320; Q8N5R7; Q9BTD8; Q9BU66"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"628.1"	"207.1"	"364.3"	"285.2"	"340.9"	"359.8"	"302.9"	"445.0"	"402.4"	"786.2"	"1703.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P2E9"	"Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5"	"0.000"	""	"5"	"7"	"11"	"6"	"1410"	"152.4"	"8.60"	"2701.26"	"13.39"	"7"	"4"	"protein metabolism;other metabolic processes;transport"	"other membranes;ER/Golgi;translational apparatus"	"other molecular function"	"Pf05104"	"6238"	"ENSG00000125844"	"RRBP1"	"A0A0A0MRV0; A2A2S6; A6NCN6; hsa:6238; O75300; O75301; Q5W165; Q96SB2; Q9BWP1; Q9H476; Q9P2E9"	"Signaling by ALK fusions and activated point mutants"	"Ectoderm differentiation"	"2"	"0"	"774.8"	"309.2"	"674.6"	"594.0"	"647.6"	"765.3"	"521.2"	"778.8"	"466.3"	"1178.9"	"2704.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IXB1"	"DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2"	"0.000"	""	"5"	"3"	"6"	"3"	"793"	"91.0"	"7.18"	"610.31"	"13.37"	"1"	"3"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"ER/Golgi"	"other molecular function"	"Pf00085, Pf00226"	"54431"	"ENSG00000077232"	"DNAJC10"	"hsa:54431; Q17RJ6; Q3B7W8; Q4ZG06; Q53QT7; Q6UWZ6; Q86T61; Q8IXB1; Q8NC82; Q8TD87; Q96K38; Q96K44; Q96K54; Q9NSY6"	""	""	"0"	"0"	"208.6"	"84.7"	"197.0"	"166.0"	"177.3"	"206.2"	"142.7"	"211.0"	"187.9"	"507.1"	"885.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62829"	"60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1"	"0.000"	""	"31"	"4"	"9"	"4"	"140"	"14.9"	"10.51"	"1739.50"	"13.36"	"4"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00238"	"9349"	"ENSG00000125691"	"RPL23"	"hsa:9349; P23131; P24048; P62829; Q29246; Q3SWV7; Q6P5S1"	"Regulation of expression of SLITs and ROBOs; SRP-dependent cotranslational protein targeting to membrane; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins; 17q12 copy number variation syndrome"	"15"	"0"	"1132.2"	"489.3"	"909.4"	"761.9"	"820.5"	"1008.9"	"730.8"	"1031.3"	"794.6"	"1362.8"	"1946.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96I24"	"Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2"	"0.000"	""	"8"	"5"	"11"	"3"	"572"	"61.6"	"8.38"	"1700.97"	"13.35"	"5"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"translational apparatus;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00013"	"8939"	"ENSG00000107164"	"FUBP3"	"A3KFK8; A3KFL0; hsa:8939; Q92946; Q96I24; Q9BVB6"	""	""	"0"	"0"	"560.7"	"135.5"	"250.4"	"198.7"	"264.3"	"227.7"	"224.8"	"277.0"	"271.0"	"400.5"	"759.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13995"	"Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD2 PE=1 SV=2"	"0.000"	""	"18"	"5"	"8"	"5"	"350"	"37.9"	"8.73"	"1347.99"	"13.35"	"4"	"4"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00763, Pf02882"	"10797"	"ENSG00000065911"	"MTHFD2"	"hsa:10797; P13995; Q53G90; Q53GV5; Q53S36; Q7Z650"	"Metabolism of folate and pterines"	"Folate metabolism; One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways"	"4"	"0"	"840.7"	"397.0"	"739.0"	"605.1"	"742.7"	"866.4"	"618.1"	"865.3"	"660.7"	"1321.3"	"2656.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07237"	"Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3"	"0.000"	""	"8"	"5"	"10"	"5"	"508"	"57.1"	"4.87"	"1570.22"	"13.33"	"5"	"5"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00085, Pf13848"	"5034"	"ENSG00000185624"	"P4HB"	"B2RDQ2; hsa:5034; P07237; P30037; P32079; Q15205; Q6LDE5"	"Hedgehog ligand biogenesis; Collagen biosynthesis and modifying enzymes; Detoxification of Reactive Oxygen Species; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Insulin processing; Interleukin-12 signaling; Interleukin-23 signaling; Chylomicron assembly; VLDL assembly; LDL remodeling"	"VEGFA-VEGFR2 signaling; Type I collagen synthesis in the context of osteogenesis imperfecta"	"13"	"0"	"797.5"	"342.0"	"683.9"	"545.4"	"706.3"	"764.4"	"525.9"	"734.3"	"569.1"	"1003.5"	"1625.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62913"	"60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2"	"0.000"	""	"17"	"3"	"8"	"3"	"178"	"20.2"	"9.60"	"1586.39"	"13.32"	"3"	"3"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00281, Pf00673"	"6135"	"ENSG00000142676"	"RPL11"	"hsa:6135; P25121; P39026; P62913; Q8TDH2; Q9Y674"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"666.3"	"256.4"	"573.0"	"490.7"	"491.7"	"606.6"	"455.2"	"595.5"	"457.1"	"888.8"	"1236.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H0D6"	"5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1"	"0.000"	""	"7"	"6"	"9"	"6"	"950"	"108.5"	"7.47"	"2224.80"	"13.30"	"5"	"4"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03159, Pf17846"	"22803"	"ENSG00000088930"	"XRN2"	"hsa:22803; Q3L8N4; Q6KGZ9; Q9BQL1; Q9H0D6; Q9NTW0; Q9NXS6; Q9UL53"	"Major pathway of rRNA processing in the nucleolus and cytosol; Association of TriC/CCT with target proteins during biosynthesis"	"mRNA processing"	"3"	"0"	"684.0"	"366.3"	"586.0"	"567.8"	"568.1"	"642.5"	"500.1"	"663.5"	"504.3"	"996.2"	"1530.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42704"	"Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3"	"0.000"	""	"5"	"6"	"10"	"6"	"1394"	"157.8"	"6.13"	"1958.89"	"13.29"	"6"	"4"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"other membranes;cytoskeleton;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf01535"	"10128"	"ENSG00000138095"	"LRPPRC"	"A0PJE3; A8K1V1; hsa:10128; P42704; Q53PC0; Q53QN7; Q6ZUD8; Q7Z7A6; Q96D84"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"Ciliary landscape"	"4"	"0"	"825.7"	"357.5"	"696.6"	"601.9"	"672.7"	"812.8"	"573.3"	"687.6"	"585.1"	"1159.6"	"2341.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14240"	"Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2"	"0.000"	""	"15"	"6"	"13"	"1"	"407"	"46.4"	"5.48"	"2715.56"	"13.28"	"6"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"1974"	"ENSG00000156976"	"EIF4A2"	"D3DNU9; hsa:1974; Q14240; Q53XJ6; Q96B90; Q96EA8"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Translation initiation complex formation; Ribosomal scanning and start codon recognition; Deadenylation of mRNA; ISG15 antiviral mechanism"	"Translation factors; Translation inhibitors in chronically activated PDGFRA cells"	"9"	"0"	"12.8"	"2.9"	"10.8"	"13.1"	"11.1"	"10.8"	"6.9"	"9.8"	"11.5"	"18.7"	"29.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P24941"	"Cyclin-dependent kinase 2 OS=Homo sapiens OX=9606 GN=CDK2 PE=1 SV=2"	"0.000"	""	"16"	"4"	"5"	"3"	"298"	"33.9"	"8.68"	"705.51"	"13.25"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1017"	"ENSG00000123374"	"CDK2"	"A8K7C6; hsa:1017; O75100; P24941"	"TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; Regulation of TP53 Degradation; SCF(Skp2)-mediated degradation of p27/p21; Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; G2 Phase; Cyclin D associated events in G1; Defective binding of RB1 mutants to E2F1,(E2F2, E2F3); Telomere Extension By Telomerase; Regulation of APC/C activators between G1/S and early anaphase; Senescence-Associated Secretory Phenotype (SASP); Factors involved in megakaryocyte development and platelet production; Processing of DNA double-strand break ends; Cyclin A/B1/B2 associated events during G2/M transition; Meiotic recombination; DNA Damage/Telomere Stress Induced Senescence; Transcriptional regulation of granulopoiesis; G0 and Early G1; Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes; p53-Dependent G1 DNA Damage Response; PTK6 Regulates Cell Cycle"	"miRNA regulation of DNA damage response; Cell cycle; Thyroid stimulating hormone (TSH) signaling pathway; Glioblastoma signaling pathways; Oncostatin M signaling pathway; Spinal cord injury; Retinoblastoma gene in cancer; Aryl hydrocarbon receptor pathway; Vitamin D receptor pathway; PI3K-Akt signaling pathway; G1 to S cell cycle control; Measles virus infection; Small cell lung cancer; DNA replication; p53 transcriptional gene network; Pleural mesothelioma; Sphingolipid metabolism in senescence; Urotensin-II-mediated signaling pathway; ID signaling pathway; TROP2 regulatory signaling; DNA damage response"	"47"	"0"	"141.5"	"61.1"	"124.2"	"109.2"	"122.7"	"140.7"	"120.5"	"158.0"	"135.2"	"408.2"	"960.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVA2"	"Septin-11 OS=Homo sapiens OX=9606 GN=SEPTIN11 PE=1 SV=3"	"0.000"	""	"12"	"4"	"7"	"3"	"429"	"49.4"	"6.81"	"1289.76"	"13.25"	"3"	"4"	"cell cycle OR cell proliferation"	"cytoskeleton;other cell component"	"other molecular function"	"Pf00735"	"55752"	"ENSG00000138758"	"SEPTIN11"	"B7Z7Z6; E9KL32; hsa:55752; Q4W5G1; Q7L4N1; Q96SP1; Q9NVA2; Q9UFY9"	""	"22q11.2 copy number variation syndrome"	"1"	"0"	"74.3"	"33.6"	"65.4"	"59.2"	"64.7"	"61.8"	"59.6"	"83.8"	"98.5"	"231.6"	"576.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O76021"	"Ribosomal L1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RSL1D1 PE=1 SV=3"	"0.000"	""	"10"	"4"	"8"	"4"	"490"	"54.9"	"10.13"	"1377.10"	"13.21"	"4"	"4"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00687"	"26156"	"ENSG00000171490"	"RSL1D1"	"B4DJ58; D3DUG7; hsa:26156; O76021; Q2M1T7; Q6PL22; Q8IWS7; Q8WUZ1; Q9HDA9; Q9Y3Z9"	""	""	"0"	"0"	"303.4"	"123.2"	"251.9"	"236.5"	"256.1"	"292.6"	"203.9"	"292.4"	"194.3"	"487.8"	"867.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P12004"	"Proliferating cell nuclear antigen OS=Homo sapiens OX=9606 GN=PCNA PE=1 SV=1"	"0.000"	""	"22"	"4"	"6"	"4"	"261"	"28.8"	"4.69"	"1149.25"	"13.12"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00705, Pf02747"	"5111"	"ENSG00000132646"	"PCNA"	"B2R897; D3DW02; hsa:5111; P12004"	"HDR through Homologous Recombination (HRR); E3 ubiquitin ligases ubiquitinate target proteins; SUMOylation of DNA replication proteins; Termination of translesion DNA synthesis; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; G1/S-Specific Transcription; Recognition of DNA damage by PCNA-containing replication complex; Transcription of E2F targets under negative control by DREAM complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Polymerase switching on the C-strand of the telomere; Polymerase switching; Removal of the Flap Intermediate; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"Cell cycle; Retinoblastoma gene in cancer; Primary focal segmental glomerulosclerosis (FSGS); Oxidative damage response; EGF/EGFR signaling pathway; G1 to S cell cycle control; DNA replication; Hepatitis B infection; Base excision repair; Nucleotide excision repair; 7q11.23 copy number variation syndrome; DNA repair pathways, full network; 16p11.2 proximal deletion syndrome; p53 transcriptional gene network; Nucleotide excision repair in xeroderma pigmentosum ; Urotensin-II-mediated signaling pathway; DNA mismatch repair; 10q11.21q11.23 copy number variation syndrome; A network map of Macrophage-stimulating protein (MSP) signaling"	"45"	"0"	"442.2"	"184.0"	"383.8"	"288.6"	"351.3"	"425.7"	"343.0"	"433.4"	"367.9"	"555.5"	"1153.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96AC1"	"Fermitin family homolog 2 OS=Homo sapiens OX=9606 GN=FERMT2 PE=1 SV=1"	"0.000"	""	"6"	"2"	"6"	"2"	"680"	"77.8"	"6.70"	"1300.71"	"13.12"	"2"	"2"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00169, Pf00373, Pf18124"	"10979"	"ENSG00000073712"	"FERMT2"	"B5TJY2; hsa:10979; Q14840; Q86TY7; Q96AC1"	"RAC1 GTPase cycle; RAC3 GTPase cycle; Cell-extracellular matrix interactions"	""	"3"	"0"	"26.4"	"16.8"	"17.3"	"17.5"	"30.4"	"34.0"	"24.2"	"27.0"	"30.2"	"144.7"	"823.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVH1"	"DnaJ homolog subfamily C member 11 OS=Homo sapiens OX=9606 GN=DNAJC11 PE=1 SV=2"	"0.000"	""	"10"	"4"	"8"	"4"	"559"	"63.2"	"8.40"	"1387.59"	"13.11"	"4"	"4"	"cell organization and biogenesis"	"other membranes;mitochondrion;nucleus"	""	"Pf00226, Pf11875"	"55735"	"ENSG00000007923"	"DNAJC11"	"hsa:55735; Q4VWF5; Q5VZN0; Q6PK20; Q6PK70; Q8NDM2; Q96CL7; Q9NVH1"	"Cristae formation"	""	"1"	"0"	"32.7"	"13.4"	"27.4"	"19.1"	"26.5"	"27.2"	"22.0"	"38.8"	"34.8"	"61.4"	"105.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13613"	"Myotubularin-related protein 1 OS=Homo sapiens OX=9606 GN=MTMR1 PE=1 SV=4"	"0.000"	""	"6"	"3"	"8"	"3"	"665"	"74.6"	"7.14"	"1396.87"	"13.04"	"3"	"3"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf02893, Pf06602"	"8776"	"ENSG00000063601"	"MTMR1"	"A0A024RC07; hsa:8776; Q13613; Q9UBX6; Q9UEM0; Q9UQD5"	"RHOF GTPase cycle; Synthesis of PIPs at the plasma membrane"	""	"2"	"0"	"66.3"	"31.4"	"65.3"	"61.6"	"63.5"	"78.2"	"62.0"	"241.6"	"367.6"	"773.0"	"1017.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96BP3"	"Peptidylprolyl isomerase domain and WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=PPWD1 PE=1 SV=1"	"0.000"	""	"10"	"5"	"7"	"5"	"646"	"73.5"	"7.15"	"894.89"	"13.02"	"3"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00160, Pf00400"	"23398"	"ENSG00000113593"	"PPWD1"	"B4DWR9; hsa:23398; Q15002; Q7KZ89; Q96BP3"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"452.3"	"176.8"	"374.0"	"306.0"	"323.3"	"370.0"	"331.1"	"367.0"	"356.6"	"521.3"	"837.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P10515"	"Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3"	"0.000"	""	"9"	"4"	"6"	"4"	"647"	"69.0"	"7.84"	"1038.17"	"12.97"	"3"	"3"	"other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf00198, Pf00364, Pf02817"	"1737"	"ENSG00000150768"	"DLAT"	"hsa:1737; P10515; Q16783; Q53EP3"	"Glyoxylate metabolism and glycine degradation; Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Neuroinflammation and glutamatergic signaling; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"8"	"0"	"264.0"	"104.1"	"246.6"	"215.4"	"221.9"	"273.5"	"190.5"	"292.8"	"226.3"	"615.4"	"1420.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07195"	"L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2"	"0.000"	""	"15"	"4"	"8"	"4"	"334"	"36.6"	"6.05"	"1352.59"	"12.94"	"4"	"4"	"other metabolic processes"	"other membranes;cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00056, Pf02866"	"3945"	"ENSG00000111716"	"LDHB"	"hsa:3945; P07195"	"Pyruvate metabolism"	"Clear cell renal cell carcinoma pathways; CCL18 signaling pathway; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"5"	"0"	"330.5"	"115.4"	"207.8"	"155.8"	"217.5"	"202.0"	"206.5"	"240.7"	"269.3"	"442.5"	"782.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BZJ0"	"Crooked neck-like protein 1 OS=Homo sapiens OX=9606 GN=CRNKL1 PE=1 SV=4"	"0.000"	""	"6"	"4"	"7"	"4"	"848"	"100.4"	"8.00"	"1288.02"	"12.93"	"3"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf02184"	"51340"	"ENSG00000101343"	"CRNKL1"	"A8K9T4; hsa:51340; Q5JY64; Q8WYI5; Q9BZI9; Q9BZJ0; Q9BZJ1; Q9BZJ2; Q9GZW7; Q9H8F8; Q9NQH5; Q9NYD8"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"398.9"	"142.6"	"247.5"	"280.4"	"225.4"	"249.8"	"200.2"	"274.6"	"260.0"	"569.7"	"1279.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27635"	"60S ribosomal protein L10 OS=Homo sapiens OX=9606 GN=RPL10 PE=1 SV=4"	"0.000"	""	"18"	"4"	"7"	"4"	"214"	"24.6"	"10.08"	"1109.96"	"12.92"	"3"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00252"	"100137264; 100146244; 100172946; 100415355; 100468790; 100724614; 100982236; 101083663; 101136536; 101344695; 101444008; 101539056; 101690567; 101867181; 101975002; 102028809; 102257301; 102442647; 102878669; 102890423; 102923570; 102957760; 103127392; 103211225; 103250904; 103731218; 104667036; 104872587; 105294701; 105302495; 105467951; 105521640; 105579731; 105727260; 105824536; 105867804; 106000161; 107160308; 108513162; 108518769; 109696857; 110954; 465944; 700795; 81764"	"ENSAMEG00000000227; ENSANAG00000036053; ENSCAFG00020009114; ENSCAFG00030015144; ENSCAFG00040021422; ENSCAFG00845028627; ENSCANG00000032226; ENSCATG00000030970; ENSCCAG00000024992; ENSCGRG00001008387; ENSCJAG00000011822; ENSCLAG00000003108; ENSCPOG00000002355; ENSECAG00000017154; ENSFCAG00000011395; ENSGGOG00000000131; ENSLCNG00005021252; ENSMFAG00000040824; ENSMLUG00000014337; ENSMMMG00000014279; ENSMMUG00000005494; ENSMNEG00000038094; ENSMPUG00000009320; ENSMUSG00000008682; ENSMUSG00000058443; ENSNGAG00000023746; ENSNLEG00000028143; ENSNVIG00000023818; ENSPANG00000008309; ENSPCOG00000027122; ENSPPAG00000034160; ENSPPYG00000020874; ENSPSMG00000015404; ENSPTIG00000005599; ENSPTRG00000043378; ENSRBIG00000042996; ENSRNOG00000056765; ENSRROG00000019247; ENSSSUG00005010590; ENSSTOG00000011857; ENSTGEG00000012563; ENSUAMG00000020454; ENSUMAG00000019583; ENSUPAG00010000252"	"LOC100768740; LOC101344695; LOC105294701; LOC112632580; Rpl10; RPL10"	"A0A091D943; A0A1S3APJ4; A0A1S3GPT7; A0A1U7SU42; A0A250YCK6; A0A286XQR8; A0A2I3FV08; A0A2J8IN69; A0A2J8RLU6; A0A2K5EV78; A0A2K5ILK8; A0A2K5LLF2; A0A2K5QER4; A0A2K5U275; A0A2K6D043; A0A2K6GRP4; A0A2K6MTH0; A0A2K6NK39; A0A2R9B361; A0A2Y9G5G6; A0A384DKX1; A0A3Q0CF07; A0A3Q7NJC4; A0A452S2Z9; A0A485PEW4; A0A667IJV2; A0A673U4F8; A0A6D2WIN2; A0A6D2XTB8; A0A6I9ME29; A0A6J0A9X4; A0A6J2E7G1; A0A6J3GU06; A0A6P3QFP2; A0A6P5P1X6; A0A6P6DLY1; A0A7J7YFN8; A0A7J8J7V5; A0A822A0T4; A0A8B7B976; A0A8B7FW91; A0A8C0K7J7; A0A8C0TBM4; A0A8C2LMI8; A0A8C2UVN1; A0A8C5ZPE8; A0A8C6S1T7; A0A8C7BXJ2; A0A8C8ZPD3; A0A8C9J452; A0A8D2F5T2; A0A8D2GF85; A0A8I3PXJ3; A0A8J8XDM4; A0A8M1M1S6; A0A9B0U593; A2AM97; A6KRS1; A9CB60; aju:106987320; aml:100468790; B0KWW6; B1MTV1; B3RFD9; C3PT02; cang:105521640; caty:105579731; ccan:109696857; cpoc:100724614; csyr:103250904; D3YC00; dnm:101444008; dord:106000161; ecb:100146244; F7AYR2; F7GKJ8; fca:101083663; G1PPT9; G2HFW2; G3S9Q9; G7Q3B3; ggo:101136536; H2PX84; I2CYS4; I3MI39; L5KDV0; L8Y8T7; M3WF14; M3YD39; mcal:110286529; mcc:700795; mcf:101867181; mlf:102442647; mmu:110954; mmur:105867804; mni:105467951; mpuf:101690567; myb:102257301; nsu:110578606; P45634; pale:102878669; pale:102890423; panu:100137264; pcoq:105824536; pps:100982236; ptg:102957760; ptr:465944; pvp:105294701; pvp:105302495; Q569M8; Q5M9K8; Q6PDV7; Q6ZWV3; rbb:108513162; rbb:108518769; rno:81764; rro:104667036; S7NR49; sara:101539056; tmu:101344695; umr:103679662; zca:113931110"	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; SRP-dependent cotranslational protein targeting to membrane; Major pathway of rRNA processing in the nucleolus and cytosol; L13a-mediated translational silencing of Ceruloplasmin expression; SRP-dependent cotranslational protein targeting to membrane; Major pathway of rRNA processing in the nucleolus and cytosol; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"15"	"0"	"338.7"	"111.3"	"350.6"	"316.5"	"331.7"	"415.9"	"263.1"	"315.6"	"223.6"	"457.4"	"795.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BRT2"	"Ubiquinol-cytochrome-c reductase complex assembly factor 2 OS=Homo sapiens OX=9606 GN=UQCC2 PE=1 SV=1"	"0.000"	""	"25"	"3"	"8"	"3"	"126"	"14.9"	"7.37"	"1182.71"	"12.90"	"3"	"3"	"cell organization and biogenesis;other biological processes"	"other membranes;mitochondrion;nucleus"	""	"Pf20180"	"84300"	"ENSG00000137288"	"UQCC2"	"B2R4I0; hsa:84300; Q9BRT2"	""	"Mitochondrial complex III assembly"	"1"	"0"	"236.4"	"114.2"	"216.3"	"173.8"	"226.2"	"232.9"	"196.4"	"249.9"	"256.3"	"873.0"	"1659.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00471"	"Exocyst complex component 5 OS=Homo sapiens OX=9606 GN=EXOC5 PE=1 SV=1"	"0.000"	""	"6"	"3"	"5"	"3"	"708"	"81.8"	"6.71"	"391.80"	"12.89"	"1"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf07393"	"10640"	"ENSG00000070367"	"EXOC5"	"B2R6C5; hsa:10640; O00471; Q8IW24"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"Ciliary landscape"	"4"	"0"	"44.7"	"16.4"	"46.0"	"36.1"	"40.7"	"52.2"	"44.2"	"64.7"	"72.1"	"245.7"	"646.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P06493"	"Cyclin-dependent kinase 1 OS=Homo sapiens OX=9606 GN=CDK1 PE=1 SV=3"	"0.000"	""	"21"	"5"	"8"	"4"	"297"	"34.1"	"8.40"	"1874.72"	"12.89"	"5"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069"	"983"	"ENSG00000170312"	"CDK1"	"A8K7C4; C9J497; hsa:983; O60764; P06493"	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A; MAPK6/MAPK4 signaling; The role of GTSE1 in G2/M progression after G2 checkpoint; Resolution of Sister Chromatid Cohesion; Recruitment of NuMA to mitotic centrosomes; Nuclear Pore Complex (NPC) Disassembly; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Regulation of TP53 Degradation; APC/C:Cdc20 mediated degradation of Cyclin B; Phosphorylation of the APC/C; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Transcriptional regulation by RUNX2; Ovarian tumor domain proteases; MASTL Facilitates Mitotic Progression; E2F-enabled inhibition of pre-replication complex formation; MAPK3 (ERK1) activation; Golgi Cisternae Pericentriolar Stack Reorganization; Condensation of Prophase Chromosomes; G1/S-Specific Transcription; Initiation of Nuclear Envelope (NE) Reformation; Condensation of Prometaphase Chromosomes; Activation of NIMA Kinases NEK9, NEK6, NEK7; G2/M DNA replication checkpoint; Depolymerization of the Nuclear Lamina; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1; Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes; Phosphorylation of Emi1"	"miRNA regulation of DNA damage response; Cell cycle; Microtubule cytoskeleton regulation; Spinal cord injury; Retinoblastoma gene in cancer; ATM signaling pathway; PPAR-alpha pathway; Nuclear receptors meta-pathway; ATM signaling in development and disease ; G1 to S cell cycle control; Cohesin complex - Cornelia de Lange syndrome; Urotensin-II-mediated signaling pathway; DNA damage response"	"49"	"1"	"511.5"	"366.6"	"424.2"	"364.7"	"481.7"	"477.5"	"375.0"	"543.6"	"610.1"	"1008.9"	"2727.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82970"	"High mobility group nucleosome-binding domain-containing protein 5 OS=Homo sapiens OX=9606 GN=HMGN5 PE=1 SV=1"	"0.000"	""	"16"	"3"	"6"	"3"	"282"	"31.5"	"4.55"	"1260.53"	"12.88"	"3"	"3"	"cell organization and biogenesis;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01101"	"79366"	"ENSG00000198157"	"HMGN5"	"hsa:79366; P82970; Q5JSL1"	""	""	"0"	"0"	"321.8"	"91.7"	"220.3"	"213.1"	"264.0"	"247.6"	"229.5"	"263.9"	"198.4"	"349.2"	"551.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75400"	"Pre-mRNA-processing factor 40 homolog A OS=Homo sapiens OX=9606 GN=PRPF40A PE=1 SV=2"	"0.000"	""	"4"	"4"	"8"	"4"	"957"	"108.7"	"7.56"	"1314.96"	"12.87"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf00397, Pf01846"	"55660"	"ENSG00000196504"	"PRPF40A"	"hsa:55660; O43856; O75400; O75404; Q8TBQ1; Q9H782; Q9NWU9; Q9P0Q2; Q9Y5A8"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"0"	"508.6"	"178.1"	"304.5"	"251.3"	"317.7"	"334.9"	"297.1"	"395.1"	"335.0"	"780.6"	"1293.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y262"	"Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1"	"0.000"	""	"10"	"5"	"9"	"5"	"564"	"66.7"	"6.34"	"1667.41"	"12.87"	"5"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity"	"Pf10255"	"51386"	"ENSG00000100129"	"EIF3L"	"B2RDG6; B4DYB2; G8JLH4; hsa:51386; Q53HQ1; Q53HT4; Q5QTR1; Q5TI15; Q6ICD2; Q9Y262"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex"	""	"6"	"0"	"425.7"	"166.4"	"364.2"	"313.0"	"398.5"	"430.5"	"314.8"	"393.7"	"311.7"	"570.4"	"1022.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15145"	"Actin-related protein 2/3 complex subunit 3 OS=Homo sapiens OX=9606 GN=ARPC3 PE=1 SV=3"	"0.000"	""	"13"	"2"	"7"	"2"	"178"	"20.5"	"8.59"	"1215.61"	"12.81"	"1"	"2"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf04062"	"10094"	"ENSG00000111229"	"ARPC3"	"hsa:10094; O00554; O15145"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"Pathogenic Escherichia coli infection"	"6"	"0"	"120.5"	"62.9"	"111.2"	"92.4"	"94.8"	"131.0"	"94.1"	"126.7"	"116.4"	"942.4"	"2938.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75380"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS6 PE=1 SV=1"	"0.000"	""	"27"	"3"	"6"	"3"	"124"	"13.7"	"8.28"	"1389.43"	"12.79"	"3"	"3"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf10276"	"4726"	"ENSG00000145494"	"NDUFS6"	"hsa:4726; O75380"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"5"	"0"	"336.2"	"110.5"	"234.5"	"185.7"	"235.4"	"278.2"	"232.6"	"291.6"	"258.6"	"542.4"	"1116.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09496"	"Clathrin light chain A OS=Homo sapiens OX=9606 GN=CLTA PE=1 SV=1"	"0.000"	""	"15"	"5"	"9"	"5"	"248"	"27.1"	"4.51"	"1172.18"	"12.70"	"4"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01086"	"1211"	"ENSG00000122705"	"CLTA"	"A8K4W3; B4DIN1; F5H6N3; hsa:1211; P09496; Q2XPN5; Q53XZ1"	"Cargo recognition for clathrin-mediated endocytosis; LDL clearance; Recycling pathway of L1; MHC class II antigen presentation; Lysosome Vesicle Biogenesis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; Retrograde neurotrophin signalling; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation; Entry of Influenza Virion into Host Cell via Endocytosis; Formation of annular gap junctions"	"Synaptic vesicle pathway; Ebola virus infection in host; Fragile X syndrome"	"17"	"0"	"999.5"	"450.5"	"951.2"	"809.9"	"863.4"	"1016.5"	"694.8"	"873.4"	"740.0"	"1310.8"	"1905.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27694"	"Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2"	"0.000"	""	"11"	"5"	"8"	"5"	"616"	"68.1"	"7.21"	"1325.56"	"12.66"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01336, Pf04057, Pf08646, Pf16900"	"6117"	"ENSG00000132383"	"RPA1"	"A8K0Y9; hsa:6117; P27694; Q59ES9"	"SUMOylation of DNA damage response and repair proteins; PCNA-Dependent Long Patch Base Excision Repair; Fanconi Anemia Pathway; Regulation of HSF1-mediated heat shock response; Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Meiotic recombination; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; HSF1 activation; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; Dual Incision in GG-NER; Removal of the Flap Intermediate; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"Homologous recombination; Retinoblastoma gene in cancer; ATR signaling; G1 to S cell cycle control; DNA replication; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"39"	"0"	"250.1"	"109.1"	"216.6"	"210.3"	"253.5"	"287.7"	"216.1"	"283.0"	"282.1"	"612.3"	"855.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43148"	"mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1"	"0.000"	""	"9"	"5"	"10"	"4"	"476"	"54.8"	"6.61"	"1533.96"	"12.65"	"5"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03291"	"8731"	"ENSG00000101654"	"RNMT"	"B0YJ90; D3DUJ5; hsa:8731; O43148; O94996; Q9UIJ9"	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE"	"mRNA processing; 15q25 copy number variation"	"5"	"0"	"279.4"	"108.2"	"253.3"	"239.1"	"261.4"	"297.1"	"204.3"	"267.0"	"255.5"	"594.8"	"1160.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NC96"	"Adaptin ear-binding coat-associated protein 1 OS=Homo sapiens OX=9606 GN=NECAP1 PE=1 SV=2"	"0.000"	""	"14"	"5"	"9"	"4"	"275"	"29.7"	"6.80"	"1644.95"	"12.65"	"5"	"4"	"transport"	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf07933"	"25977"	"ENSG00000089818"	"NECAP1"	"hsa:25977; Q2NL73; Q5XG95; Q6NWY6; Q8N153; Q8NC96; Q8NCB0; Q9BU52; Q9Y407"	"Golgi Associated Vesicle Biogenesis; Cargo recognition for clathrin-mediated endocytosis"	""	"3"	"1"	"160.6"	"73.2"	"147.8"	"137.6"	"177.0"	"248.0"	"535.2"	"2128.3"	"2204.4"	"3767.6"	"3345.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P1U0"	"DNA-directed RNA polymerase I subunit RPA12 OS=Homo sapiens OX=9606 GN=ZNRD1 PE=1 SV=1"	"0.000"	""	"43"	"3"	"4"	"3"	"126"	"13.9"	"5.06"	"305.87"	"12.63"	"1"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01096"	"30834"	"ENSG00000066379; ENSG00000206502; ENSG00000224859; ENSG00000233795; ENSG00000235176; ENSG00000235443; ENSG00000236808; ENSG00000236949"	"POLR1H"	"hsa:30834; Q9P1U0"	"RNA Polymerase I Transcription Initiation; B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"Pyrimidine metabolism; 2q13 copy number variation syndrome"	"7"	"0"	"91.6"	"40.2"	"73.4"	"60.9"	"80.3"	"81.9"	"67.1"	"161.9"	"352.9"	"1364.5"	"2437.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P20674"	"Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2"	"0.000"	""	"49"	"5"	"8"	"4"	"150"	"16.8"	"6.79"	"1249.59"	"12.58"	"4"	"4"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf02284"	"9377"	"ENSG00000178741"	"COX5A"	"hsa:9377; P20674; P30045; Q8TB65"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly; 5q35 copy number variation; Arachidonate epoxygenase / epoxide hydrolase"	"8"	"1"	"824.8"	"204.3"	"417.7"	"269.2"	"467.0"	"472.2"	"432.9"	"525.5"	"555.7"	"864.4"	"1917.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99615"	"DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2"	"0.000"	""	"7"	"4"	"10"	"4"	"494"	"56.4"	"6.96"	"1917.54"	"12.58"	"4"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00226, Pf13181, Pf13414, Pf13432"	"7266"	"ENSG00000168259"	"DNAJC7"	"hsa:7266; Q7Z784; Q99615"	"Regulation of HSF1-mediated heat shock response"	"Constitutive androstane receptor pathway; Pregnane X receptor pathway; Nuclear receptors meta-pathway"	"4"	"0"	"523.0"	"252.1"	"593.2"	"537.9"	"528.4"	"664.7"	"429.4"	"574.2"	"419.7"	"1139.6"	"2529.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y490"	"Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3"	"0.000"	""	"2"	"3"	"4"	"3"	"2541"	"269.6"	"6.07"	"380.41"	"12.57"	"1"	"3"	"cell adhesion;cell organization and biogenesis;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00373, Pf01608, Pf08913, Pf09141, Pf16511"	"7094"	"ENSG00000137076"	"TLN1"	"A6NMY0; hsa:7094; Q86YD0; Q9NZQ2; Q9UHH8; Q9UPX3; Q9Y490"	"Platelet degranulation ; p130Cas linkage to MAPK signaling for integrins; Signaling by BRAF and RAF1 fusions; XBP1(S) activates chaperone genes; SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion; Smooth Muscle Contraction; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; GRB2:SOS provides linkage to MAPK signaling for Integrins"	"Integrin-mediated cell adhesion; Primary focal segmental glomerulosclerosis (FSGS); Focal adhesion; TROP2 regulatory signaling"	"18"	"0"	"34.5"	"11.5"	"34.9"	"25.9"	"27.1"	"40.1"	"20.2"	"37.1"	"58.8"	"251.7"	"410.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TBX8"	"Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma OS=Homo sapiens OX=9606 GN=PIP4K2C PE=1 SV=3"	"0.000"	""	"11"	"5"	"9"	"5"	"421"	"47.3"	"6.84"	"1118.11"	"12.51"	"4"	"5"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf01504"	"79837"	"ENSG00000166908"	"PIP4K2C"	"B2RDL3; B4DM11; B4DY44; hsa:79837; Q8TBX8; Q9H6N2"	"Synthesis of PIPs at the plasma membrane; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; PI5P Regulates TP53 Acetylation; Synthesis of PIPs in the nucleus"	"Regulation of actin cytoskeleton"	"5"	"0"	"133.5"	"63.0"	"121.9"	"145.8"	"138.8"	"238.5"	"325.9"	"751.6"	"918.2"	"2665.2"	"2256.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UFW8"	"CGG triplet repeat-binding protein 1 OS=Homo sapiens OX=9606 GN=CGGBP1 PE=1 SV=2"	"0.000"	""	"25"	"4"	"7"	"4"	"167"	"18.8"	"8.95"	"785.53"	"12.47"	"3"	"4"	"cell organization and biogenesis;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	""	"8545"	"ENSG00000163320"	"CGGBP1"	"D3DU38; hsa:8545; O15183; Q9UFW8"	""	""	"0"	"0"	"268.5"	"138.6"	"245.2"	"217.9"	"228.8"	"257.4"	"206.7"	"314.9"	"332.5"	"662.8"	"997.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P0K7"	"Ankycorbin OS=Homo sapiens OX=9606 GN=RAI14 PE=1 SV=2"	"0.000"	""	"3"	"2"	"5"	"2"	"980"	"110.0"	"6.21"	"874.78"	"12.47"	"1"	"2"	"other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf00023, Pf12796"	"26064"	"ENSG00000039560"	"RAI14"	"E9PED3; hsa:26064; Q6V1W9; Q7Z5I4; Q7Z733; Q9P0K7; Q9P2L2; Q9Y3T5"	""	""	"0"	"0"	"52.8"	"25.2"	"47.4"	"39.5"	"46.3"	"47.1"	"35.6"	"57.0"	"62.3"	"240.5"	"710.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01780"	"Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2"	"0.000"	""	"5"	"4"	"7"	"4"	"885"	"100.8"	"8.46"	"1016.94"	"12.46"	"3"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00570, Pf01612, Pf08066"	"5394"	"ENSG00000171824"	"EXOSC10"	"B1AKQ0; B1AKQ1; hsa:5394; Q01780; Q15158"	"Major pathway of rRNA processing in the nucleolus and cytosol"	""	"1"	"0"	"258.2"	"127.1"	"223.5"	"185.9"	"213.9"	"252.3"	"176.2"	"265.3"	"263.1"	"605.5"	"1133.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86TV6"	"Tetratricopeptide repeat protein 7B OS=Homo sapiens OX=9606 GN=TTC7B PE=1 SV=3"	"0.000"	""	"5"	"3"	"5"	"3"	"843"	"94.1"	"6.89"	"812.91"	"12.44"	"2"	"3"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol"	""	"Pf12895, Pf13181, Pf13424, Pf19440"	"145567"	"ENSG00000165914"	"TTC7B"	"hsa:145567; Q86TV6; Q86U24; Q86VT3"	""	""	"0"	"0"	"45.1"	"18.3"	"29.2"	"40.6"	"42.4"	"48.9"	"30.1"	"49.8"	"57.1"	"255.7"	"492.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35606"	"Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2"	"0.000"	""	"6"	"4"	"7"	"4"	"906"	"102.4"	"5.27"	"1890.95"	"12.42"	"4"	"3"	"transport"	"other membranes;cytosol;ER/Golgi"	"other molecular function"	"Pf00400, Pf04053"	"9276"	"ENSG00000184432"	"COPB2"	"B4DZI8; hsa:9276; P35606"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport"	""	"2"	"0"	"537.5"	"262.1"	"571.0"	"482.6"	"523.9"	"626.5"	"410.8"	"554.2"	"399.8"	"725.8"	"1327.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14160"	"Protein scribble homolog OS=Homo sapiens OX=9606 GN=SCRIB PE=1 SV=4"	"0.000"	""	"3"	"5"	"8"	"5"	"1630"	"174.8"	"5.07"	"1004.73"	"12.41"	"3"	"5"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"611.7"	"279.2"	"459.5"	"402.9"	"468.7"	"474.8"	"432.6"	"570.1"	"569.6"	"1474.0"	"2465.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BZF1"	"Oxysterol-binding protein-related protein 8 OS=Homo sapiens OX=9606 GN=OSBPL8 PE=1 SV=3"	"0.000"	""	"5"	"3"	"5"	"3"	"889"	"101.1"	"6.96"	"875.46"	"12.38"	"2"	"3"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00169, Pf01237"	"114882"	"ENSG00000091039"	"OSBPL8"	"A8K1T2; E9PE66; E9PE68; hsa:114882; Q52LQ3; Q68D75; Q8WXP8; Q9BZF1; Q9P277"	"Acyl chain remodelling of PS"	""	"1"	"0"	"42.9"	"15.8"	"41.8"	"27.9"	"28.1"	"45.6"	"35.4"	"57.9"	"54.8"	"241.4"	"422.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99733"	"Nucleosome assembly protein 1-like 4 OS=Homo sapiens OX=9606 GN=NAP1L4 PE=1 SV=1"	"0.000"	""	"16"	"6"	"10"	"5"	"375"	"42.8"	"4.69"	"1734.76"	"12.36"	"6"	"4"	"cell organization and biogenesis"	"nucleus;other cell component"	"other molecular function"	"Pf00956"	"4676"	"ENSG00000205531; ENSG00000273562"	"NAP1L4"	"B2R6J4; F5HFY4; hsa:4676; Q99733"	""	""	"0"	"1"	"607.3"	"320.0"	"603.2"	"497.3"	"548.2"	"645.5"	"518.5"	"680.9"	"487.5"	"818.6"	"1376.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5SRE5"	"Nucleoporin NUP188 homolog OS=Homo sapiens OX=9606 GN=NUP188 PE=1 SV=1"	"0.000"	""	"2"	"3"	"6"	"3"	"1749"	"195.9"	"6.73"	"1365.05"	"12.31"	"3"	"3"	"transport"	"cytosol;nucleus"	"other molecular function"	"Pf10487"	"23511"	"ENSG00000095319"	"NUP188"	"hsa:23511; Q14675; Q2TA87; Q5SRE5; Q7Z3K8; Q8IWF1"	"Vpr-mediated nuclear import of PICs; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Regulation of HSF1-mediated heat shock response; HCMV Late Events; HCMV Early Events; Transcriptional regulation by small RNAs; SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Transport of Mature mRNA Derived from an Intronless Transcript; tRNA processing in the nucleus; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; snRNP Assembly; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); Postmitotic nuclear pore complex (NPC) reformation"	""	"29"	"0"	"136.8"	"46.2"	"128.2"	"110.3"	"111.8"	"126.1"	"80.2"	"125.7"	"94.0"	"183.7"	"336.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P48444"	"Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1"	"0.000"	""	"7"	"3"	"8"	"3"	"511"	"57.2"	"6.21"	"1464.68"	"12.24"	"3"	"3"	"transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi"	""	"Pf00928, Pf01217"	"372"	"ENSG00000095139"	"ARCN1"	"B4E1X2; E9PEU4; hsa:372; P48444; Q52M80"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport"	"miR-517 relationship with ARCN1 and USP1"	"3"	"0"	"341.5"	"169.2"	"318.8"	"313.5"	"338.2"	"398.0"	"262.3"	"363.9"	"262.8"	"509.7"	"889.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95292"	"Vesicle-associated membrane protein-associated protein B/C OS=Homo sapiens OX=9606 GN=VAPB PE=1 SV=3"	"0.000"	""	"14"	"3"	"4"	"2"	"243"	"27.2"	"7.30"	"481.51"	"12.19"	"1"	"3"	"cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00635"	"9217"	"ENSG00000124164"	"VAPB"	"A2A2F2; hsa:9217; O95292; O95293; Q9P0H0"	"RHOC GTPase cycle; RHOA GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RHOD GTPase cycle; Sphingolipid de novo biosynthesis"	"Ciliary landscape"	"7"	"1"	"61.3"	"21.0"	"41.8"	"36.2"	"46.5"	"43.8"	"41.1"	"54.3"	"47.0"	"188.5"	"659.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15369"	"Elongin-C OS=Homo sapiens OX=9606 GN=ELOC PE=1 SV=1"	"0.000"	""	"38"	"3"	"6"	"3"	"112"	"12.5"	"4.78"	"1121.07"	"12.12"	"3"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf03931"	"6921"	"ENSG00000154582"	"ELOC"	"E5RGD9; hsa:6921; Q15369; Q567Q6"	"Regulation of expression of SLITs and ROBOs; Antigen processing: Ubiquitination & Proteasome degradation; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Vif-mediated degradation of APOBEC3G; Neddylation; Inactivation of CSF3 (G-CSF) signaling; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes"	"Dual hijack model of Vif in HIV infection; VEGFA-VEGFR2 signaling; Type 2 papillary renal cell carcinoma; Hijack of ubiquitination by SARS-CoV-2"	"21"	"0"	"79.0"	"36.4"	"45.1"	"46.1"	"62.3"	"54.2"	"52.1"	"53.8"	"64.5"	"79.2"	"164.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P21796"	"Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2"	"0.000"	""	"13"	"4"	"8"	"3"	"283"	"30.8"	"8.54"	"808.27"	"12.10"	"3"	"4"	"cell-cell signaling;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"transporter activity;other molecular function"	"Pf01459"	"7416"	"ENSG00000213585"	"VDAC1"	"B3KVK4; D3DQ93; hsa:7416; P21796; Q5FVE7; Q9UIQ5; Q9UPL0"	"Ub-specific processing proteases; Pyruvate metabolism; Mitochondrial protein import; PINK1-PRKN Mediated Mitophagy; Mitochondrial calcium ion transport"	"Alzheimer's disease and miRNA effects; Alzheimer's disease; Arsenic metabolism and reactive oxygen species generation; Cholesterol metabolism; Fatty Acids and Lipoproteins Transport in Hepatocytes"	"10"	"1"	"472.8"	"113.5"	"219.6"	"134.5"	"250.8"	"232.4"	"220.5"	"283.3"	"298.3"	"734.1"	"1793.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IX01"	"SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2"	"0.000"	""	"6"	"4"	"7"	"4"	"1082"	"120.1"	"7.28"	"1212.15"	"12.10"	"3"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf01585, Pf01805"	"10147"	"ENSG00000064607"	"SUGP2"	"C9JI71; hsa:10147; O15071; O60369; Q5JPH7; Q8IX01; Q8WUF7"	""	"mRNA processing"	"1"	"0"	"99.2"	"44.3"	"87.5"	"59.1"	"80.9"	"84.9"	"70.4"	"84.0"	"76.8"	"140.7"	"283.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9GZS3"	"WD repeat-containing protein 61 OS=Homo sapiens OX=9606 GN=WDR61 PE=1 SV=1"	"0.000"	""	"10"	"4"	"7"	"4"	"305"	"33.6"	"5.47"	"1143.58"	"12.04"	"3"	"4"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00400"	"80349"	"ENSG00000140395"	"SKIC8"	"D3DW84; hsa:80349; Q6IA22; Q7Z4X4; Q9GZS3"	"Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events; E3 ubiquitin ligases ubiquitinate target proteins; mRNA decay by 3' to 5' exoribonuclease"	""	"5"	"0"	"639.9"	"249.9"	"563.8"	"520.1"	"566.9"	"701.3"	"502.9"	"654.3"	"453.5"	"958.8"	"1666.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P31930"	"Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3"	"0.000"	""	"6"	"3"	"7"	"3"	"480"	"52.6"	"6.37"	"1140.17"	"12.04"	"2"	"3"	"other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00675, Pf05193"	"7384"	"ENSG00000010256"	"UQCRC1"	"B2R7R8; hsa:7384; P31930; Q96DD2"	"Respiratory electron transport"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex III assembly"	"4"	"0"	"554.3"	"244.6"	"476.5"	"453.8"	"492.2"	"600.1"	"480.9"	"539.5"	"461.6"	"837.5"	"1400.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9ULH0"	"Kinase D-interacting substrate of 220 kDa OS=Homo sapiens OX=9606 GN=KIDINS220 PE=1 SV=3"	""	""	"2"	"3"	"4"	"3"	"1771"	"196.4"	"6.62"	""	"12.01"	""	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf07693, Pf12796"	"57498"	"ENSG00000134313"	"KIDINS220"	"A1L4N4; hsa:57498; Q4VC08; Q6MZU2; Q9H889; Q9H9E4; Q9NT37; Q9UF42; Q9ULH0"	"RND1 GTPase cycle; RND2 GTPase cycle; ARMS-mediated activation"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; Neural crest cell migration in cancer"	"5"	"0"	"38.2"	"13.7"	"36.1"	"32.8"	"40.8"	"43.9"	"29.9"	"50.8"	"77.4"	"274.5"	"706.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQG0"	"Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2"	"0.000"	""	"5"	"5"	"8"	"5"	"1328"	"148.8"	"9.28"	"1199.25"	"11.97"	"4"	"4"	"cell organization and biogenesis;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04931"	"10514"	"ENSG00000132382"	"MYBBP1A"	"hsa:10514; Q86VM3; Q9BQG0; Q9BW49; Q9P0V5; Q9UF99"	"B-WICH complex positively regulates rRNA expression"	"Energy metabolism; 10q11.21q11.23 copy number variation syndrome"	"3"	"0"	"76.0"	"27.8"	"61.7"	"55.0"	"53.5"	"62.7"	"49.7"	"63.6"	"63.9"	"101.1"	"157.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBQ5"	"Eukaryotic translation initiation factor 3 subunit K OS=Homo sapiens OX=9606 GN=EIF3K PE=1 SV=1"	"0.000"	""	"23"	"4"	"7"	"4"	"218"	"25.0"	"4.93"	"1611.52"	"11.97"	"4"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf10075"	"27335"	"ENSG00000178982; ENSG00000282986"	"EIF3K"	"A8K0I9; B7ZAM9; hsa:27335; Q96IQ0; Q9UBQ5; Q9Y6D1"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	""	"6"	"0"	"616.0"	"302.7"	"560.3"	"445.9"	"507.5"	"657.4"	"476.1"	"563.6"	"470.2"	"675.8"	"1043.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96JJ3"	"Engulfment and cell motility protein 2 OS=Homo sapiens OX=9606 GN=ELMO2 PE=1 SV=2"	"0.000"	""	"6"	"3"	"6"	"3"	"720"	"82.6"	"5.90"	"1114.56"	"11.96"	"3"	"3"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol"	"signal transduction activity or receptor binding;other molecular function"	"Pf04727, Pf11841, Pf16457"	"63916"	"ENSG00000062598"	"ELMO2"	"E1P5T3; hsa:63916; Q5JVZ6; Q7Z5G9; Q96CJ2; Q96JJ3; Q96ME5; Q96PA9; Q9H938; Q9H9L5; Q9HAH0; Q9NQQ6"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHOG GTPase cycle; VEGFA-VEGFR2 Pathway; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"	""	"5"	"0"	"82.7"	"28.3"	"72.5"	"50.9"	"62.9"	"89.2"	"90.8"	"156.6"	"139.0"	"401.5"	"584.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P28074"	"Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3"	"0.000"	""	"13"	"3"	"6"	"3"	"263"	"28.5"	"6.92"	"1189.86"	"11.96"	"3"	"3"	"protein metabolism;other metabolic processes;stress response"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00227"	"5693"	"ENSG00000100804"	"PSMB5"	"B2R4N9; B4DUM9; D3DS43; E9PAV2; hsa:5693; P28074; Q16242; Q6PEW2; Q7Z3B5; Q86T01; Q9TNN9"	"Regulation of expression of SLITs and ROBOs; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; SCF(Skp2)-mediated degradation of p27/p21; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"62"	"0"	"262.9"	"95.2"	"271.4"	"261.1"	"288.9"	"337.6"	"239.3"	"368.0"	"239.2"	"403.0"	"597.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60828"	"Polyglutamine-binding protein 1 OS=Homo sapiens OX=9606 GN=PQBP1 PE=1 SV=1"	"0.000"	""	"23"	"4"	"6"	"4"	"265"	"30.5"	"6.33"	"1374.61"	"11.93"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	""	"10084"	"ENSG00000102103"	"PQBP1"	"C9JQA1; hsa:10084; O60828; Q4VY25; Q4VY26; Q4VY27; Q4VY29; Q4VY30; Q4VY34; Q4VY35; Q4VY36; Q4VY37; Q4VY38; Q9GZP2; Q9GZU4; Q9GZZ4"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"498.6"	"214.0"	"432.6"	"363.2"	"413.1"	"448.2"	"355.9"	"533.4"	"392.8"	"766.3"	"1344.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5UIP0"	"Telomere-associated protein RIF1 OS=Homo sapiens OX=9606 GN=RIF1 PE=1 SV=2"	"0.000"	""	"2"	"3"	"6"	"3"	"2472"	"274.3"	"5.52"	"1107.94"	"11.90"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	""	"Pf12231"	"55183"	"ENSG00000080345"	"RIF1"	"A6NC27; C9JBR1; hsa:55183; Q5H9R3; Q5UIP0; Q5UIP2; Q66YK6; Q6PRU2; Q8TE94; Q99772; Q9H830; Q9H9B9; Q9NVP5; Q9Y4R4"	"Nonhomologous End-Joining (NHEJ)"	"ATM signaling in development and disease ; 10q11.21q11.23 copy number variation syndrome"	"3"	"0"	"146.0"	"59.0"	"132.1"	"108.1"	"144.7"	"138.1"	"94.0"	"134.1"	"126.8"	"242.2"	"413.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19022"	"Cadherin-2 OS=Homo sapiens OX=9606 GN=CDH2 PE=1 SV=4"	"0.000"	""	"5"	"3"	"5"	"3"	"906"	"99.7"	"4.81"	"979.75"	"11.90"	"2"	"3"	"cell adhesion;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00028, Pf01049, Pf08758"	"1000"	"ENSG00000170558"	"CDH2"	"A8MWK3; B0YIY6; hsa:1000; P19022; Q14923; Q8N173"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Myogenesis; Adherens junctions interactions"	"Neural crest differentiation; Arrhythmogenic right ventricular cardiomyopathy; Brain-derived neurotrophic factor (BDNF) signaling pathway; Primary focal segmental glomerulosclerosis (FSGS); Splicing factor NOVA regulated synaptic proteins; Epithelial to mesenchymal transition in colorectal cancer; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; Pleural mesothelioma; CCL18 signaling pathway; GDNF signaling; A network map of Macrophage-stimulating protein (MSP) signaling"	"16"	"0"	"157.5"	"54.6"	"129.5"	"103.6"	"129.8"	"139.0"	"126.7"	"173.3"	"139.4"	"260.4"	"396.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q09161"	"Nuclear cap-binding protein subunit 1 OS=Homo sapiens OX=9606 GN=NCBP1 PE=1 SV=1"	"0.000"	""	"8"	"5"	"8"	"5"	"790"	"91.8"	"6.43"	"1740.95"	"11.89"	"5"	"3"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02854, Pf09088, Pf09090"	"4686"	"ENSG00000136937"	"NCBP1"	"B2R718; hsa:4686; Q09161; Q59G76; Q5T1V0; Q5T7X2"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Abortive elongation of HIV-1 transcript in the absence of Tat; RNA Polymerase II Pre-transcription Events; RNA polymerase II transcribes snRNA genes; mRNA Capping; mRNA Splicing - Major Pathway; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Signaling by FGFR2 IIIa TM; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; snRNP Assembly; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"mRNA processing; 3q29 copy number variation syndrome"	"29"	"0"	"318.1"	"120.9"	"280.5"	"275.5"	"250.6"	"324.0"	"248.9"	"334.7"	"261.0"	"442.5"	"770.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVP1"	"ATP-dependent RNA helicase DDX18 OS=Homo sapiens OX=9606 GN=DDX18 PE=1 SV=2"	"0.000"	""	"6"	"2"	"3"	"2"	"670"	"75.4"	"9.50"	"547.01"	"11.87"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271, Pf13959"	"8886"	"ENSG00000088205"	"DDX18"	"hsa:8886; Q6GTZ9; Q6IAU4; Q92732; Q9BQB7; Q9NVP1"	""	""	"0"	"0"	"72.7"	"23.3"	"74.9"	"66.1"	"73.3"	"85.9"	"57.3"	"85.0"	"79.1"	"401.1"	"738.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P0L0"	"Vesicle-associated membrane protein-associated protein A OS=Homo sapiens OX=9606 GN=VAPA PE=1 SV=3"	"0.000"	""	"16"	"3"	"5"	"2"	"249"	"27.9"	"8.62"	"821.81"	"11.87"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00635"	"9218"	"ENSG00000101558"	"VAPA"	"A6NDZ0; D3DUI3; hsa:9218; O75453; Q5U0E7; Q9P0L0; Q9UBZ2"	"Neutrophil degranulation; Insertion of tail-anchored proteins into the endoplasmic reticulum membrane; Sphingolipid de novo biosynthesis"	"Exercise-induced circadian regulation; Cholesterol metabolism"	"5"	"0"	"47.9"	"22.5"	"32.9"	"19.4"	"21.5"	"31.3"	"25.0"	"43.6"	"54.9"	"104.5"	"333.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99460"	"26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PSMD1 PE=1 SV=2"	"0.000"	""	"2"	"2"	"8"	"2"	"953"	"105.8"	"5.39"	"1463.09"	"11.84"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01851, Pf13646, Pf18004"	"5707"	"ENSG00000173692"	"PSMD1"	"B8ZZH9; hsa:5707; Q24JU0; Q53TI2; Q6GMU5; Q6P2P4; Q6PJM7; Q6PKG9; Q86VU1; Q8IV79; Q99460"	"Neutrophil degranulation; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; MAPK6/MAPK4 signaling; The role of GTSE1 in G2/M progression after G2 checkpoint; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"64"	"0"	"225.6"	"96.7"	"184.8"	"177.1"	"195.8"	"216.6"	"133.5"	"178.4"	"143.2"	"290.3"	"459.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96J01"	"THO complex subunit 3 OS=Homo sapiens OX=9606 GN=THOC3 PE=1 SV=1"	"0.000"	""	"8"	"3"	"7"	"3"	"351"	"38.7"	"6.09"	"1051.67"	"11.81"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00400, Pf08662, Pf12894"	"84321"	"ENSG00000051596"	"THOC3"	"hsa:84321; Q6NZ53; Q96J01"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	""	"3"	"0"	"461.4"	"190.4"	"364.4"	"305.7"	"336.2"	"390.0"	"275.5"	"395.6"	"329.9"	"651.6"	"1141.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96F07"	"Cytoplasmic FMR1-interacting protein 2 OS=Homo sapiens OX=9606 GN=CYFIP2 PE=1 SV=2"	"0.000"	""	"3"	"4"	"8"	"1"	"1278"	"148.3"	"7.31"	"1410.83"	"11.76"	"4"	"4"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf05994, Pf07159"	"26999"	"ENSG00000055163"	"CYFIP2"	"A6NLT2; D3DQJ3; hsa:26999; Q53EN5; Q96F07; Q9NTK4; Q9ULQ2; Q9UN29"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RAC1 GTPase cycle; RHO GTPases Activate WASPs and WAVEs; VEGFA-VEGFR2 Pathway"	"Fragile X syndrome; Regulation of actin cytoskeleton"	"7"	"0"	"40.9"	"20.5"	"36.5"	"32.4"	"30.6"	"46.5"	"35.9"	"56.5"	"72.8"	"196.7"	"361.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14737"	"Programmed cell death protein 5 OS=Homo sapiens OX=9606 GN=PDCD5 PE=1 SV=3"	"0.000"	""	"29"	"4"	"9"	"4"	"125"	"14.3"	"6.04"	"1495.64"	"11.73"	"4"	"3"	"other biological processes"	"cytosol;nucleus"	"enzyme regulator activity;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf01984"	"9141"	"ENSG00000105185"	"PDCD5"	"B4DE64; hsa:9141; O14737; Q53YC9; Q6IB70"	""	""	"0"	"0"	"942.6"	"512.2"	"829.9"	"913.9"	"957.8"	"1071.4"	"971.0"	"1098.9"	"795.9"	"1285.9"	"2362.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14561"	"Acyl carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFAB1 PE=1 SV=3"	"0.000"	""	"10"	"1"	"4"	"1"	"156"	"17.4"	"4.93"	"1301.26"	"11.69"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"other membranes;cytosol;mitochondrion;nucleus"	"translation activity;other molecular function"	"Pf00550"	"4706"	"ENSG00000004779"	"NDUFAB1"	"B2R4M1; hsa:4706; O14561; Q9UNV1"	"Glyoxylate metabolism and glycine degradation; Mitochondrial Fatty Acid Beta-Oxidation; Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"7"	"0"	"126.3"	"48.5"	"116.2"	"76.2"	"91.8"	"115.4"	"83.6"	"148.6"	"152.5"	"283.1"	"540.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14795"	"Protein unc-13 homolog B OS=Homo sapiens OX=9606 GN=UNC13B PE=1 SV=2"	"0.000"	""	"3"	"3"	"6"	"3"	"1591"	"180.6"	"5.99"	"1276.33"	"11.68"	"3"	"3"	"cell-cell signaling;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00130, Pf00168, Pf06292"	"10497"	"ENSG00000198722"	"UNC13B"	"hsa:10497; O14795; Q2NKJ5; Q5VYM8"	"Glutamate Neurotransmitter Release Cycle; Serotonin Neurotransmitter Release Cycle; Norepinephrine Neurotransmitter Release Cycle; Dopamine Neurotransmitter Release Cycle; Acetylcholine Neurotransmitter Release Cycle"	"Synaptic vesicle pathway; 16p11.2 proximal deletion syndrome; Monoamine transport"	"8"	"0"	"36.0"	"13.6"	"38.7"	"31.9"	"29.7"	"47.5"	"30.2"	"50.3"	"59.0"	"197.4"	"461.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14166"	"Tubulin--tyrosine ligase-like protein 12 OS=Homo sapiens OX=9606 GN=TTLL12 PE=1 SV=2"	"0.000"	""	"7"	"3"	"5"	"3"	"644"	"74.4"	"5.53"	"708.53"	"11.68"	"2"	"3"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03133"	"23170"	"ENSG00000100304"	"TTLL12"	"hsa:23170; Q14166; Q20WK5; Q9UGU3"	"Carboxyterminal post-translational modifications of tubulin"	""	"1"	"0"	"151.2"	"59.8"	"135.6"	"131.1"	"129.1"	"151.2"	"123.7"	"147.3"	"113.9"	"225.9"	"437.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15291"	"Retinoblastoma-binding protein 5 OS=Homo sapiens OX=9606 GN=RBBP5 PE=1 SV=2"	"0.000"	""	"10"	"3"	"5"	"3"	"538"	"59.1"	"5.10"	"708.31"	"11.67"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00400"	"5929"	"ENSG00000117222"	"RBBP5"	"A8K272; hsa:5929; Q15291; Q7Z6D8; Q8NDZ7"	"Neddylation; Formation of WDR5-containing histone-modifying complexes; Formation of the beta-catenin:TCF transactivating complex; Deactivation of the beta-catenin transactivating complex; Activation of anterior HOX genes in hindbrain development during early embryogenesis; PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"	"Kleefstra syndrome"	"8"	"0"	"254.8"	"89.7"	"202.9"	"181.3"	"193.8"	"208.5"	"205.0"	"280.3"	"228.1"	"408.7"	"742.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BRP1"	"Programmed cell death protein 2-like OS=Homo sapiens OX=9606 GN=PDCD2L PE=1 SV=1"	"0.000"	""	"10"	"3"	"6"	"3"	"358"	"39.4"	"4.86"	"1183.23"	"11.64"	"3"	"2"	"cell cycle OR cell proliferation;other biological processes"	"other cell component"	""	"Pf04194"	"84306"	"ENSG00000126249"	"PDCD2L"	"hsa:84306; Q9BRP1"	""	""	"0"	"0"	"182.7"	"76.6"	"149.1"	"140.1"	"176.4"	"194.7"	"143.1"	"213.6"	"195.0"	"554.2"	"996.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96HS1"	"Serine/threonine-protein phosphatase PGAM5, mitochondrial OS=Homo sapiens OX=9606 GN=PGAM5 PE=1 SV=2"	"0.000"	""	"8"	"2"	"6"	"2"	"289"	"32.0"	"8.68"	"1255.87"	"11.63"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion"	"enzyme regulator activity;other molecular function"	"Pf00300"	"192111"	"ENSG00000247077"	"PGAM5"	"A9LN06; C9IZY7; hsa:192111; Q96HS1; Q96JB0"	""	"NRF2-ARE regulation"	"1"	"0"	"533.8"	"181.3"	"334.5"	"276.3"	"315.5"	"366.0"	"294.7"	"413.2"	"390.3"	"773.0"	"1478.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O75521"	"Enoyl-CoA delta isomerase 2, mitochondrial OS=Homo sapiens OX=9606 GN=ECI2 PE=1 SV=4"	""	""	"9"	"2"	"2"	"2"	"394"	"43.6"	"9.00"	""	"11.59"	""	"2"	"other metabolic processes"	"cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00378, Pf00887"	"10455"	"ENSG00000198721"	"ECI2"	"hsa:10455; O75521; Q5JYK5; Q5JYK7; Q7L124; Q8N0X0; Q9BUE9; Q9H0T9; Q9NQH1; Q9NYH7; Q9UN55"	""	""	"0"	"0"	"131.5"	"73.6"	"124.8"	"96.6"	"127.9"	"132.6"	"108.9"	"142.6"	"132.9"	"368.8"	"904.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52209"	"6-phosphogluconate dehydrogenase, decarboxylating OS=Homo sapiens OX=9606 GN=PGD PE=1 SV=3"	"0.000"	""	"9"	"3"	"4"	"3"	"483"	"53.1"	"7.23"	"411.00"	"11.59"	"1"	"3"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00393, Pf03446"	"5226"	"ENSG00000142657"	"PGD"	"A8K2Y9; B4DQJ8; hsa:5226; P52209; Q9BWD8"	"NFE2L2 regulates pentose phosphate pathway genes; Pentose phosphate pathway"	"Pentose phosphate metabolism; Nuclear receptors meta-pathway; NRF2 pathway; VEGFA-VEGFR2 signaling; Metabolic reprogramming in colon cancer"	"7"	"0"	"30.2"	"15.6"	"23.6"	"31.1"	"31.3"	"35.9"	"28.9"	"29.6"	"28.1"	"81.6"	"235.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52435"	"DNA-directed RNA polymerase II subunit RPB11-a OS=Homo sapiens OX=9606 GN=POLR2J PE=1 SV=1"	"0.000"	""	"26"	"3"	"5"	"3"	"117"	"13.3"	"5.86"	"656.69"	"11.57"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13656"	"5439"	"ENSG00000005075"	"POLR2J"	"A5D6V8; hsa:5439; O43375; P52435"	"mRNA Splicing - Major Pathway; Transcriptional regulation by small RNAs; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Inhibition of DNA recombination at telomere; Processing of Capped Intron-Containing Pre-mRNA; Viral Messenger RNA Synthesis; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Signaling by FGFR2 IIIa TM"	"Pyrimidine metabolism; Eukaryotic transcription initiation"	"43"	"0"	"207.7"	"104.9"	"226.9"	"187.5"	"209.9"	"249.0"	"204.3"	"214.8"	"170.7"	"241.0"	"457.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92905"	"COP9 signalosome complex subunit 5 OS=Homo sapiens OX=9606 GN=COPS5 PE=1 SV=4"	"0.000"	""	"9"	"3"	"5"	"3"	"334"	"37.6"	"6.54"	"386.34"	"11.54"	"1"	"3"	"protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01398, Pf18323"	"10987"	"ENSG00000121022"	"COPS5"	"hsa:10987; O15386; Q6AW95; Q86WQ4; Q92905; Q9BQ17"	"Formation of TC-NER Pre-Incision Complex; Cargo recognition for clathrin-mediated endocytosis; Neddylation; DNA Damage Recognition in GG-NER"	""	"4"	"0"	"142.0"	"50.2"	"140.7"	"140.1"	"130.9"	"276.6"	"348.0"	"634.0"	"545.8"	"1466.2"	"3918.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H3K6"	"BolA-like protein 2 OS=Homo sapiens OX=9606 GN=BOLA2 PE=1 SV=1"	"0.000"	""	"33"	"2"	"5"	"2"	"86"	"10.1"	"6.52"	"918.30"	"11.52"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01722"	"552900; 654483"	"ENSG00000169627; ENSG00000183336"	"BOLA2; BOLA2B"	"A1L454; A7YDY3; hsa:552900; hsa:654483; Q9H3K6"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	""	"1"	"0"	"248.9"	"126.2"	"206.3"	"210.1"	"227.9"	"238.3"	"203.6"	"236.7"	"199.5"	"305.0"	"559.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7RTV0"	"PHD finger-like domain-containing protein 5A OS=Homo sapiens OX=9606 GN=PHF5A PE=1 SV=1"	"0.000"	""	"32"	"4"	"7"	"4"	"110"	"12.4"	"8.41"	"871.62"	"11.50"	"3"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03660"	"84844"	"ENSG00000100410"	"PHF5A"	"hsa:84844; Q7RTV0; Q9UH06"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"0"	"993.3"	"339.3"	"775.8"	"719.2"	"716.5"	"864.1"	"645.6"	"826.4"	"597.8"	"1118.0"	"1678.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86WW8"	"Cytochrome c oxidase assembly factor 5 OS=Homo sapiens OX=9606 GN=COA5 PE=1 SV=1"	"0.001"	""	"45"	"3"	"4"	"3"	"74"	"8.4"	"8.68"	"283.82"	"11.49"	"1"	"3"	"cell organization and biogenesis"	"mitochondrion"	""	"Pf10203"	"493753"	"ENSG00000183513"	"COA5"	"hsa:493753; Q86WW8"	""	""	"0"	"0"	"318.8"	"176.0"	"348.8"	"338.7"	"354.2"	"461.1"	"344.0"	"455.4"	"369.2"	"1181.0"	"2265.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96NB3"	"Zinc finger protein 830 OS=Homo sapiens OX=9606 GN=ZNF830 PE=1 SV=2"	"0.000"	""	"13"	"4"	"7"	"3"	"372"	"42.0"	"5.31"	"1276.95"	"11.48"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf12874"	"91603"	"ENSG00000198783"	"ZNF830"	"hsa:91603; Q96F60; Q96GZ5; Q96NB3; Q9BU38"	"mRNA Splicing - Major Pathway; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of TC-NER Pre-Incision Complex"	"17q12 copy number variation syndrome"	"6"	"0"	"207.7"	"79.7"	"182.3"	"153.5"	"172.1"	"191.6"	"153.1"	"182.7"	"164.1"	"291.0"	"414.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94842"	"TOX high mobility group box family member 4 OS=Homo sapiens OX=9606 GN=TOX4 PE=1 SV=1"	"0.000"	""	"5"	"3"	"6"	"3"	"621"	"66.2"	"5.06"	"1138.00"	"11.43"	"3"	"3"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00505"	"9878"	"ENSG00000092203"	"TOX4"	"B4DPY8; B4DSM0; E7EV69; hsa:9878; O94842"	""	""	"0"	"0"	"187.2"	"70.5"	"168.9"	"132.5"	"166.2"	"179.7"	"125.4"	"171.6"	"149.2"	"289.7"	"743.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13427"	"Peptidyl-prolyl cis-trans isomerase G OS=Homo sapiens OX=9606 GN=PPIG PE=1 SV=2"	"0.000"	""	"6"	"4"	"8"	"4"	"754"	"88.6"	"10.29"	"1158.48"	"11.41"	"4"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00160"	"9360"	"ENSG00000138398"	"PPIG"	"D3DPC5; D3DPC6; hsa:9360; O00706; Q13427; Q53R40; Q53SN4; Q96DG9"	"mRNA Splicing - Major Pathway; SARS-CoV-1 activates/modulates innate immune responses"	""	"2"	"0"	"501.0"	"146.5"	"304.2"	"275.2"	"325.0"	"372.9"	"318.7"	"511.2"	"486.6"	"789.7"	"1144.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2S6"	"Translation machinery-associated protein 7 OS=Homo sapiens OX=9606 GN=TMA7 PE=1 SV=1"	"0.000"	""	"36"	"4"	"12"	"3"	"64"	"7.1"	"9.99"	"2263.69"	"11.38"	"4"	"4"	""	""	""	"Pf09072"	"51372"	"ENSG00000232112"	"TMA7"	"hsa:51372; Q9P052; Q9Y2S6"	""	""	"0"	"2"	"2240.1"	"1667.0"	"2331.2"	"1749.2"	"1843.4"	"2292.2"	"1845.2"	"2386.5"	"2235.6"	"4693.1"	"6330.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14558"	"Phosphoribosyl pyrophosphate synthase-associated protein 1 OS=Homo sapiens OX=9606 GN=PRPSAP1 PE=1 SV=2"	"0.000"	""	"12"	"3"	"6"	"3"	"356"	"39.4"	"7.20"	"1014.14"	"11.37"	"3"	"3"	"other metabolic processes"	"other cell component"	"enzyme regulator activity;other molecular function"	"Pf13793, Pf14572"	"5635"	"ENSG00000161542"	"PRPSAP1"	"B2R6M4; hsa:5635; Q14558; Q96H06"	""	""	"0"	"0"	"61.3"	"33.6"	"55.4"	"46.5"	"53.8"	"62.3"	"50.0"	"72.1"	"75.2"	"158.7"	"358.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92665"	"28S ribosomal protein S31, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS31 PE=1 SV=3"	"0.000"	""	"12"	"4"	"7"	"4"	"395"	"45.3"	"9.29"	"1023.47"	"11.34"	"3"	"4"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf15433"	"10240"	"ENSG00000102738"	"MRPS31"	"B2RCS3; hsa:10240; Q5VYC8; Q8WTV8; Q92665"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"253.3"	"138.6"	"216.8"	"208.6"	"213.3"	"279.2"	"202.4"	"256.2"	"204.4"	"451.8"	"784.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63279"	"SUMO-conjugating enzyme UBC9 OS=Homo sapiens OX=9606 GN=UBE2I PE=1 SV=1"	"0.000"	""	"26"	"3"	"4"	"3"	"158"	"18.0"	"8.66"	"413.46"	"11.31"	"1"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00179"	"7329"	"ENSG00000103275"	"UBE2I"	"D3DU69; hsa:7329; P50550; P63279; Q15698; Q59GX1; Q86VB3"	"SUMOylation of RNA binding proteins; Formation of Incision Complex in GG-NER; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; Meiotic synapsis; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of DNA replication proteins; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; SUMOylation of intracellular receptors; Processing of DNA double-strand break ends; Vitamin D (calciferol) metabolism; SUMOylation of transcription factors; Postmitotic nuclear pore complex (NPC) reformation; Negative regulation of activity of TFAP2 (AP-2) family transcription factors; Maturation of nucleoprotein; SUMOylation of immune response proteins; SUMOylation of nuclear envelope proteins; Maturation of nucleoprotein; SUMO is transferred from E1 to E2 (UBE2I, UBC9)"	"Androgen receptor signaling pathway; TAR syndrome"	"25"	"0"	"115.8"	"55.6"	"116.9"	"96.0"	"96.8"	"137.3"	"108.0"	"135.2"	"127.3"	"356.6"	"1294.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P15531"	"Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1"	"0.000"	""	"35"	"4"	"7"	"1"	"152"	"17.1"	"6.19"	"957.25"	"11.31"	"3"	"4"	"DNA metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"translation activity;kinase activity;other molecular function"	"Pf00334"	"4830"	"ENSG00000239672"	"NME1"	"hsa:4830; P15531; Q6FGK3; Q86XQ2; Q9UDJ6"	"Interconversion of nucleotide di- and triphosphates; Azathioprine ADME; Ribavirin ADME"	"Pyrimidine metabolism"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16836"	"Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=HADH PE=1 SV=3"	"0.000"	""	"13"	"4"	"7"	"4"	"314"	"34.3"	"8.85"	"1012.36"	"11.30"	"3"	"4"	"other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00725, Pf02737"	"3033"	"ENSG00000138796"	"HADH"	"hsa:3033; J3KQ17; O00324; O00397; O00753; Q16836; Q4W5B4"	"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of butanoyl-CoA to acetyl-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA"	"Fatty acid beta-oxidation; Fatty acid biosynthesis; Mitochondrial long chain fatty acid beta-oxidation; Amino acid metabolism; IL-18 signaling pathway; Mitochondrial fatty acid oxidation disorders"	"11"	"0"	"338.8"	"138.8"	"283.0"	"243.7"	"297.7"	"322.9"	"260.7"	"313.4"	"269.8"	"648.8"	"1743.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14157"	"Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2"	"0.000"	""	"4"	"3"	"6"	"3"	"1087"	"114.5"	"7.11"	"1098.25"	"11.30"	"2"	"3"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	""	"Pf12478"	"9898"	"ENSG00000143569"	"UBAP2L"	"B4E0U8; hsa:9898; Q14157; Q5VU75; Q5VU76; Q9BTU3; Q9UGL2; Q9UGL3; Q9UGL4; Q9UGL5"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"396.3"	"159.9"	"348.2"	"229.1"	"311.7"	"309.1"	"209.2"	"335.4"	"353.9"	"578.2"	"865.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75822"	"Eukaryotic translation initiation factor 3 subunit J OS=Homo sapiens OX=9606 GN=EIF3J PE=1 SV=2"	"0.000"	""	"25"	"5"	"9"	"5"	"258"	"29.0"	"4.83"	"2320.64"	"11.27"	"4"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf08597"	"8669"	"ENSG00000104131"	"EIF3J"	"B4DUI3; F5H425; hsa:8669; O75822; Q9BUD2; Q9H8Q2; Q9UI65"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"8"	"0"	"887.8"	"366.9"	"852.4"	"730.0"	"841.2"	"998.4"	"704.6"	"957.0"	"598.8"	"1238.3"	"2044.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49720"	"Proteasome subunit beta type-3 OS=Homo sapiens OX=9606 GN=PSMB3 PE=1 SV=2"	"0.000"	""	"15"	"2"	"5"	"2"	"205"	"22.9"	"6.55"	"916.60"	"11.22"	"2"	"2"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf00227"	"5691"	"ENSG00000275903; ENSG00000277791"	"PSMB3"	"hsa:5691; P31147; P49720; Q0P6J7; Q96E27"	"Separation of Sister Chromatids; Neddylation; The role of GTSE1 in G2/M progression after G2 checkpoint; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; SCF(Skp2)-mediated degradation of p27/p21; Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"62"	"0"	"131.9"	"39.0"	"100.6"	"104.4"	"123.3"	"130.4"	"103.6"	"137.2"	"96.7"	"155.5"	"246.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00161"	"Synaptosomal-associated protein 23 OS=Homo sapiens OX=9606 GN=SNAP23 PE=1 SV=1"	"0.000"	""	"21"	"2"	"3"	"2"	"211"	"23.3"	"5.01"	"609.89"	"11.22"	"1"	"2"	"cell-cell signaling;cell organization and biogenesis;stress response;transport"	"plasma membrane;other membranes;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00835"	"8773"	"ENSG00000092531"	"SNAP23"	"hsa:8773; O00161; O00162; Q13602; Q6IAE3"	"RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; ER-Phagosome pathway; Translocation of SLC2A4 (GLUT4) to the plasma membrane; RAC3 GTPase cycle; RHOB GTPase cycle; RHOJ GTPase cycle; RHOF GTPase cycle; Neutrophil degranulation; trans-Golgi Network Vesicle Budding"	"Insulin signaling"	"13"	"0"	"100.1"	"29.1"	"65.9"	"58.3"	"72.8"	"71.2"	"60.0"	"82.3"	"65.9"	"143.8"	"263.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NS86"	"LanC-like protein 2 OS=Homo sapiens OX=9606 GN=LANCL2 PE=1 SV=1"	""	""	"11"	"3"	"3"	"3"	"450"	"50.8"	"7.43"	""	"11.18"	""	"3"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"other molecular function"	"Pf05147"	"55915"	"ENSG00000132434"	"LANCL2"	"B2R8D4; hsa:55915; Q6NSL4; Q8TCQ3; Q9BSR1; Q9NS86"	""	""	"0"	"0"	"64.4"	"30.5"	"72.9"	"53.4"	"65.7"	"69.7"	"71.0"	"99.2"	"97.8"	"254.4"	"697.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15599"	"Na(+)/H(+) exchange regulatory cofactor NHE-RF2 OS=Homo sapiens OX=9606 GN=SLC9A3R2 PE=1 SV=2"	"0.000"	""	"8"	"2"	"4"	"2"	"337"	"37.4"	"7.93"	"1181.47"	"11.17"	"2"	"2"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00595, Pf09007"	"9351"	"ENSG00000065054"	"NHERF2"	"D3DU84; D3DU85; H3BSV6; hsa:9351; O00272; O00556; Q15599; Q3KQY7"	""	""	"0"	"0"	"83.0"	"40.7"	"66.5"	"65.2"	"75.4"	"74.5"	"68.7"	"99.4"	"98.6"	"259.1"	"623.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15427"	"Splicing factor 3B subunit 4 OS=Homo sapiens OX=9606 GN=SF3B4 PE=1 SV=1"	"0.000"	""	"7"	"3"	"8"	"3"	"424"	"44.4"	"8.56"	"1187.56"	"11.09"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00076"	"10262"	"ENSG00000143368"	"SF3B4"	"hsa:10262; Q15427; Q5SZ63"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"mRNA processing; 10q22q23 copy number variation"	"4"	"0"	"1041.2"	"388.3"	"847.5"	"626.2"	"767.7"	"837.7"	"653.9"	"783.9"	"649.3"	"1153.2"	"1693.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P013"	"Spliceosome-associated protein CWC15 homolog OS=Homo sapiens OX=9606 GN=CWC15 PE=1 SV=2"	"0.001"	""	"16"	"2"	"3"	"2"	"229"	"26.6"	"5.71"	"252.71"	"11.09"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity"	"Pf04889"	"51503"	"ENSG00000150316"	"CWC15"	"B2RC17; hsa:51503; Q05BV9; Q05DM1; Q9P013; Q9UI29"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"76.9"	"30.6"	"62.7"	"49.5"	"63.3"	"74.3"	"55.9"	"70.5"	"60.4"	"93.5"	"251.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P10606"	"Cytochrome c oxidase subunit 5B, mitochondrial OS=Homo sapiens OX=9606 GN=COX5B PE=1 SV=2"	"0.000"	""	"29"	"3"	"6"	"3"	"129"	"13.7"	"8.81"	"1203.53"	"11.05"	"3"	"3"	"other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf01215"	"1329"	"ENSG00000135940"	"COX5B"	"hsa:1329; P10606; Q53YB7; Q96J18; Q99610"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly; 5q35 copy number variation"	"7"	"0"	"516.8"	"189.8"	"344.7"	"260.8"	"355.7"	"362.6"	"353.6"	"382.0"	"391.8"	"571.5"	"872.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99497"	"Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2"	"0.000"	""	"21"	"4"	"7"	"4"	"189"	"19.9"	"6.79"	"1518.96"	"11.03"	"4"	"3"	"cell-cell signaling;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf01965"	"11315"	"ENSG00000116288"	"PARK7"	"B2R4Z1; hsa:11315; O14805; Q6DR95; Q7LFU2; Q99497"	"Late endosomal microautophagy; Aggrephagy; SUMOylation of transcription cofactors; Chaperone Mediated Autophagy"	"Androgen receptor signaling pathway; Synaptic vesicle pathway; Parkinson's disease pathway"	"7"	"0"	"448.9"	"191.0"	"385.2"	"312.9"	"411.3"	"447.3"	"310.8"	"447.3"	"360.1"	"614.3"	"1044.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NUQ3"	"Gamma-taxilin OS=Homo sapiens OX=9606 GN=TXLNG PE=1 SV=2"	"0.000"	""	"6"	"3"	"4"	"3"	"528"	"60.5"	"7.52"	"426.11"	"11.00"	"1"	"3"	"cell cycle OR cell proliferation;other biological processes"	"other membranes;cytosol;nucleus"	"other molecular function"	"Pf09728"	"55787"	"ENSG00000086712"	"TXLNG"	"hsa:55787; Q2KQ75; Q5JNZ7; Q9NUQ3; Q9P0X1"	""	""	"0"	"0"	"96.4"	"42.8"	"94.3"	"77.0"	"81.8"	"94.2"	"57.9"	"97.5"	"96.9"	"454.8"	"1072.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TDN4"	"CDK5 and ABL1 enzyme substrate 1 OS=Homo sapiens OX=9606 GN=CABLES1 PE=1 SV=2"	"0.000"	""	"6"	"3"	"6"	"3"	"633"	"67.6"	"9.17"	"1279.22"	"10.99"	"3"	"3"	"cell cycle OR cell proliferation;developmental processes;other biological processes"	"cytosol;nucleus"	""	"Pf00134"	"91768"	"ENSG00000134508"	"CABLES1"	"B4DK60; hsa:91768; Q8N3Y8; Q8NA22; Q8TDN4; Q9BTG1"	"Factors involved in megakaryocyte development and platelet production; Cyclin E associated events during G1/S transition ; Cyclin A:Cdk2-associated events at S phase entry"	""	"3"	"0"	"29.0"	"10.0"	"33.1"	"26.2"	"31.5"	"50.9"	"66.6"	"107.0"	"133.7"	"261.9"	"405.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UJV9"	"Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2"	"0.000"	""	"8"	"5"	"8"	"5"	"622"	"69.8"	"6.84"	"1222.85"	"10.99"	"4"	"4"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00270, Pf00271"	"51428"	"ENSG00000183258"	"DDX41"	"B2RDC8; hsa:51428; Q96BK6; Q96K05; Q9NT96; Q9NW04; Q9UJV9"	"mRNA Splicing - Major Pathway; Regulation of innate immune responses to cytosolic DNA; IRF3-mediated induction of type I IFN"	"5q35 copy number variation"	"5"	"0"	"484.4"	"220.3"	"445.3"	"356.0"	"388.6"	"484.7"	"394.0"	"638.4"	"453.9"	"884.0"	"1279.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14136"	"Glial fibrillary acidic protein OS=Homo sapiens OX=9606 GN=GFAP PE=1 SV=1"	"0.000"	""	"8"	"3"	"6"	"1"	"432"	"49.9"	"5.52"	"798.45"	"10.98"	"1"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00038, Pf04732"	"2670"	"ENSG00000131095"	"GFAP"	"A7REI1; B2RD44; D3DX59; E9PAX3; hsa:2670; P14136; Q53H98; Q5D055; Q6ZQS3; Q7Z5J6; Q7Z5J7; Q96KS4; Q96P18; Q9UFD0"	"Nuclear signaling by ERBB4; Chaperone Mediated Autophagy"	"Neural crest differentiation; Spinal cord injury; Neuroinflammation and glutamatergic signaling"	"5"	"0"	"39.2"	"17.8"	"43.5"	"39.0"	"39.6"	"43.9"	"35.8"	"49.6"	"35.0"	"65.3"	"104.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49321"	"Nuclear autoantigenic sperm protein OS=Homo sapiens OX=9606 GN=NASP PE=1 SV=2"	"0.000"	""	"4"	"4"	"7"	"4"	"788"	"85.2"	"4.30"	"1040.17"	"10.94"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf10516"	"4678"	"ENSG00000132780"	"NASP"	"A8K6H2; B4DQP3; D3DQ07; F5H3J2; hsa:4678; P49321; Q53GW5; Q5T622; Q5T625; Q96A69; Q9BTW2"	""	""	"0"	"0"	"855.6"	"338.5"	"687.4"	"581.9"	"752.5"	"793.1"	"621.3"	"774.0"	"636.8"	"1144.4"	"1705.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60508"	"Pre-mRNA-processing factor 17 OS=Homo sapiens OX=9606 GN=CDC40 PE=1 SV=1"	"0.000"	""	"8"	"4"	"7"	"4"	"579"	"65.5"	"7.06"	"1486.97"	"10.89"	"4"	"3"	"RNA metabolism OR transcription;other metabolic processes;developmental processes"	"nucleus"	"nucleic acid binding activity"	"Pf00400"	"51362"	"ENSG00000168438"	"CDC40"	"B2RBC5; hsa:51362; O60508; O75471; Q5SRN0; Q9UPG1"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway"	"mRNA processing"	"5"	"0"	"251.7"	"66.6"	"167.9"	"170.0"	"193.0"	"207.3"	"139.8"	"224.1"	"186.9"	"595.2"	"818.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P38606"	"V-type proton ATPase catalytic subunit A OS=Homo sapiens OX=9606 GN=ATP6V1A PE=1 SV=2"	"0.000"	""	"6"	"3"	"6"	"3"	"617"	"68.3"	"5.52"	"1191.46"	"10.89"	"3"	"3"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00006, Pf02874, Pf16886"	"523"	"ENSG00000114573"	"ATP6V1A"	"B2RBR8; B7Z1R5; D3DN75; hsa:523; P38606; Q53YD9; Q96DY6; Q9UHY3"	"Amino acids regulate mTORC1; ROS and RNS production in phagocytes; Insulin receptor recycling; Transferrin endocytosis and recycling; Ion channel transport"	"Proximal tubule transport"	"6"	"0"	"107.3"	"50.5"	"83.4"	"64.1"	"80.9"	"86.0"	"70.2"	"88.6"	"80.1"	"125.5"	"177.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q06587"	"E3 ubiquitin-protein ligase RING1 OS=Homo sapiens OX=9606 GN=RING1 PE=1 SV=2"	"0.001"	""	"11"	"2"	"3"	"1"	"406"	"42.4"	"5.62"	"261.59"	"10.89"	"1"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00097, Pf16207"	"6015"	"ENSG00000204227; ENSG00000206287; ENSG00000226788; ENSG00000228520; ENSG00000231115; ENSG00000235107"	"RING1"	"A8JZZ0; hsa:6015; Q06587; Q5JP96; Q5SQW2; Q86V19"	"Oxidative Stress Induced Senescence; SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6"	"Pleural mesothelioma; Notch signaling pathway"	"11"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62917"	"60S ribosomal protein L8 OS=Homo sapiens OX=9606 GN=RPL8 PE=1 SV=2"	"0.000"	""	"13"	"4"	"7"	"4"	"257"	"28.0"	"11.03"	"908.32"	"10.85"	"3"	"4"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00181, Pf03947"	"6132"	"ENSG00000161016"	"RPL8"	"A8K094; D3DWN2; hsa:6132; P25120; P62917; Q567Q7; Q969V7; Q9BWQ9"	"Major pathway of rRNA processing in the nucleolus and cytosol; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Selenocysteine synthesis; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"1363.2"	"569.3"	"1037.7"	"961.5"	"1007.5"	"1217.3"	"905.9"	"1211.6"	"964.0"	"1563.7"	"1902.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BZZ5"	"Apoptosis inhibitor 5 OS=Homo sapiens OX=9606 GN=API5 PE=1 SV=3"	"0.000"	""	"7"	"3"	"6"	"3"	"524"	"59.0"	"7.34"	"1121.50"	"10.85"	"3"	"3"	"other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf05918"	"8539"	"ENSG00000166181"	"API5"	"B4DGR0; B4DRJ2; B4E283; D3DR21; G3V1C3; hsa:8539; O15441; Q9BZZ5; Q9Y4J7"	""	""	"0"	"0"	"407.8"	"211.7"	"342.2"	"280.0"	"331.5"	"387.2"	"292.8"	"358.3"	"259.6"	"501.4"	"868.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P06730"	"Eukaryotic translation initiation factor 4E OS=Homo sapiens OX=9606 GN=EIF4E PE=1 SV=2"	"0.000"	""	"17"	"4"	"5"	"4"	"217"	"25.1"	"6.15"	"827.85"	"10.78"	"2"	"3"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01652"	"1977"	"ENSG00000151247"	"EIF4E"	"B7Z6V1; D6RCQ6; hsa:1977; P06730; Q96E95"	"Deadenylation of mRNA; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; mTORC1-mediated signalling"	"Translation factors; Leptin signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Interleukin-1 (IL-1) structural pathway; Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4); Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; 4-hydroxytamoxifen, dexamethasone, and retinoic acids regulation of p27 expression; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Prader-Willi and Angelman syndrome; PI3K-Akt signaling pathway; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Head and neck squamous cell carcinoma; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; Host-pathogen interaction of human coronaviruses - MAPK signaling; Hypertrophy model; Interferon type I signaling pathways"	"31"	"0"	"382.7"	"172.4"	"374.8"	"320.9"	"374.5"	"449.2"	"333.8"	"432.7"	"390.7"	"1314.8"	"3441.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2A7"	"Nck-associated protein 1 OS=Homo sapiens OX=9606 GN=NCKAP1 PE=1 SV=1"	"0.000"	""	"4"	"4"	"7"	"4"	"1128"	"128.7"	"6.62"	"1562.14"	"10.76"	"4"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	""	"Pf09735"	"10787"	"ENSG00000061676"	"NCKAP1"	"hsa:10787; O60329; Q53QN5; Q53S94; Q53Y35; Q9Y2A7"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; VEGFA-VEGFR2 Pathway"	"Exercise-induced circadian regulation; Regulation of actin cytoskeleton"	"9"	"0"	"106.3"	"50.6"	"103.4"	"89.1"	"101.7"	"113.0"	"114.3"	"134.8"	"170.4"	"351.9"	"876.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NNW5"	"WD repeat-containing protein 6 OS=Homo sapiens OX=9606 GN=WDR6 PE=1 SV=1"	"0.000"	""	"4"	"4"	"8"	"4"	"1121"	"121.6"	"6.87"	"1189.63"	"10.76"	"4"	"4"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf00400"	"11180"	"ENSG00000178252"	"WDR6"	"B4DHK2; hsa:11180; Q3MIT1; Q9NNW5; Q9UF63"	"RND2 GTPase cycle; RHOV GTPase cycle; RHOU GTPase cycle; RND3 GTPase cycle; RND1 GTPase cycle"	""	"5"	"0"	"247.0"	"82.6"	"162.1"	"149.5"	"148.7"	"195.4"	"148.2"	"196.4"	"168.7"	"680.8"	"1490.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UHR4"	"Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 OS=Homo sapiens OX=9606 GN=BAIAP2L1 PE=1 SV=2"	"0.000"	""	"8"	"3"	"6"	"3"	"511"	"56.8"	"8.68"	"1204.47"	"10.74"	"3"	"3"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"cytoskeletal activity;other molecular function"	"Pf08397, Pf14604"	"55971"	"ENSG00000006453"	"BAIAP2L1"	"A4D268; hsa:55971; Q75L21; Q75L22; Q96CV4; Q9H5F5; Q9UHR4; Q9Y2M8"	"RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOF GTPase cycle"	""	"4"	"0"	"62.3"	"27.5"	"55.7"	"45.9"	"48.6"	"58.4"	"42.0"	"76.6"	"113.7"	"685.4"	"676.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVM6"	"DnaJ homolog subfamily C member 17 OS=Homo sapiens OX=9606 GN=DNAJC17 PE=1 SV=1"	"0.000"	""	"20"	"5"	"7"	"5"	"304"	"34.7"	"8.53"	"1494.00"	"10.74"	"4"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf00226"	"55192"	"ENSG00000104129"	"DNAJC17"	"hsa:55192; Q9NVM6"	""	""	"0"	"0"	"108.4"	"43.4"	"92.2"	"92.0"	"102.0"	"111.4"	"84.3"	"135.5"	"157.2"	"499.8"	"1439.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43314"	"Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 OS=Homo sapiens OX=9606 GN=PPIP5K2 PE=1 SV=3"	"0.000"	""	"3"	"4"	"6"	"4"	"1243"	"140.3"	"8.22"	"640.72"	"10.73"	"2"	"4"	"other metabolic processes;other biological processes"	"cytosol"	"kinase activity;other molecular function"	"Pf00328, Pf18086"	"23262"	"ENSG00000145725"	"PPIP5K2"	"A1NI53; A6NGS8; hsa:23262; O43314; Q8TB50"	"Synthesis of pyrophosphates in the cytosol"	""	"1"	"0"	"136.1"	"58.9"	"134.3"	"108.3"	"131.5"	"143.1"	"121.1"	"183.7"	"173.6"	"652.9"	"1399.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L0Y3"	"tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2"	"0.000"	""	"8"	"4"	"8"	"4"	"403"	"47.3"	"9.36"	"1136.87"	"10.70"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01746"	"54931"	"ENSG00000174173"	"TRMT10C"	"hsa:54931; Q7L0Y3; Q9NRG5; Q9NX54; Q9Y596"	"tRNA processing in the mitochondrion; tRNA modification in the mitochondrion; rRNA processing in the mitochondrion"	""	"3"	"0"	"368.6"	"182.6"	"362.9"	"283.6"	"323.8"	"414.4"	"306.0"	"420.4"	"347.6"	"946.3"	"1993.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15226"	"NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2"	"0.000"	""	"6"	"3"	"6"	"3"	"690"	"77.6"	"8.79"	"1258.11"	"10.68"	"3"	"3"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01424, Pf01585"	"55922"	"ENSG00000186416"	"NKRF"	"G3V1N1; hsa:55922; O15226; Q4VC41; Q9UJ91"	""	"Pathogenesis of SARS-CoV-2 mediated by nsp9-nsp10 complex; Network map of SARS-CoV-2 signaling pathway"	"2"	"0"	"166.1"	"58.0"	"154.0"	"116.4"	"133.3"	"156.9"	"115.0"	"144.2"	"96.4"	"189.7"	"310.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NRZ9"	"Lymphoid-specific helicase OS=Homo sapiens OX=9606 GN=HELLS PE=1 SV=1"	"0.000"	""	"6"	"4"	"4"	"4"	"838"	"97.0"	"7.93"	"449.38"	"10.67"	"1"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00176, Pf00271"	"3070"	"ENSG00000119969"	"HELLS"	"B2RB41; hsa:3070; Q3LID1; Q6I7N7; Q76H76; Q76H77; Q76H78; Q76H79; Q76H80; Q76H81; Q7Z397; Q7Z5X2; Q8N6P4; Q9H4P5; Q9NRZ9"	""	"Apoptosis; Apoptosis-related network due to altered Notch3 in ovarian cancer"	"2"	"0"	"296.9"	"107.0"	"238.2"	"233.5"	"259.6"	"287.1"	"208.4"	"311.6"	"183.6"	"602.7"	"1743.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63208"	"S-phase kinase-associated protein 1 OS=Homo sapiens OX=9606 GN=SKP1 PE=1 SV=2"	"0.000"	""	"12"	"2"	"5"	"2"	"163"	"18.6"	"4.54"	"1399.10"	"10.66"	"2"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf01466, Pf03931"	"6500"	"ENSG00000113558"	"SKP1"	"D3DQ97; D3DQ98; hsa:6500; P34991; P63208; Q8TAY2"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; SCF-beta-TrCP mediated degradation of Emi1; Vpu mediated degradation of CD4; Degradation of beta-catenin by the destruction complex; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; NIK-->noncanonical NF-kB signaling; Orc1 removal from chromatin; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Neddylation; SCF(Skp2)-mediated degradation of p27/p21; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Regulation of PLK1 Activity at G2/M Transition; Circadian Clock; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Cyclin D associated events in G1; Regulation of BACH1 activity; MAP3K8 (TPL2)-dependent MAPK1/3 activation; NOTCH1 Intracellular Domain Regulates Transcription; Prolactin receptor signaling; Iron uptake and transport; Nuclear events stimulated by ALK signaling in cancer; Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling"	"Cell cycle; TNF-alpha signaling pathway; Breast cancer pathway; Small cell lung cancer; Notch signaling pathway"	"38"	"0"	"364.2"	"160.1"	"341.1"	"280.8"	"348.9"	"412.0"	"289.8"	"372.2"	"237.3"	"515.4"	"997.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N3U4"	"Cohesin subunit SA-2 OS=Homo sapiens OX=9606 GN=STAG2 PE=1 SV=3"	"0.000"	""	"3"	"3"	"7"	"3"	"1231"	"141.2"	"5.43"	"912.20"	"10.66"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf08514"	"10735"	"ENSG00000101972"	"STAG2"	"B1AMT5; D3DTF5; hsa:10735; O00540; Q5JTI6; Q68DE9; Q8N3U4; Q9H1N8"	"Estrogen-dependent gene expression; Resolution of Sister Chromatid Cohesion; SUMOylation of DNA damage response and repair proteins; Separation of Sister Chromatids; Meiotic synapsis; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"Cell cycle; Cohesin complex - Cornelia de Lange syndrome"	"9"	"0"	"208.4"	"62.7"	"156.2"	"128.8"	"149.0"	"172.2"	"140.6"	"199.2"	"184.6"	"375.7"	"1125.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P60866"	"40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1"	"0.000"	""	"19"	"2"	"6"	"2"	"119"	"13.4"	"9.94"	"877.71"	"10.66"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00338"	"6224"	"ENSG00000008988"	"RPS20"	"B2R4F4; B4DW28; hsa:6224; P17075; P60866; Q5M8S9"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"381.7"	"160.0"	"314.7"	"246.9"	"350.6"	"400.3"	"281.0"	"345.7"	"259.8"	"519.2"	"865.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NYB0"	"Telomeric repeat-binding factor 2-interacting protein 1 OS=Homo sapiens OX=9606 GN=TERF2IP PE=1 SV=1"	"0.000"	""	"9"	"2"	"7"	"2"	"399"	"44.2"	"4.73"	"1089.48"	"10.65"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf08914, Pf11626, Pf16589"	"54386"	"ENSG00000166848"	"TERF2IP"	"B4DQN4; hsa:54386; Q4W4Y2; Q8WYZ3; Q9NWR2; Q9NYB0"	"DNA Damage/Telomere Stress Induced Senescence; Meiotic synapsis; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; Packaging Of Telomere Ends; Polymerase switching on the C-strand of the telomere; Removal of the Flap Intermediate from the C-strand; Telomere Extension By Telomerase; Telomere C-strand synthesis initiation"	"Splicing factor NOVA regulated synaptic proteins; SARS-CoV-2 mitochondrial chronic oxidative stress and endothelial dysfunction"	"16"	"0"	"68.4"	"30.5"	"59.0"	"47.4"	"58.6"	"70.0"	"44.0"	"57.1"	"43.4"	"72.1"	"123.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WVC0"	"RNA polymerase-associated protein LEO1 OS=Homo sapiens OX=9606 GN=LEO1 PE=1 SV=1"	"0.000"	""	"9"	"5"	"7"	"5"	"666"	"75.4"	"4.51"	"1195.11"	"10.64"	"4"	"3"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytoskeleton;nucleus"	"other molecular function"	"Pf04004"	"123169"	"ENSG00000166477"	"LEO1"	"hsa:123169; Q8WVC0; Q96N99"	"E3 ubiquitin ligases ubiquitinate target proteins; Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events; Formation of the beta-catenin:TCF transactivating complex"	"Endoderm differentiation"	"6"	"0"	"350.6"	"152.4"	"323.6"	"299.5"	"339.9"	"401.2"	"276.4"	"383.1"	"255.1"	"485.2"	"791.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P84022"	"Mothers against decapentaplegic homolog 3 OS=Homo sapiens OX=9606 GN=SMAD3 PE=1 SV=1"	"0.000"	""	"11"	"3"	"5"	"3"	"425"	"48.1"	"7.15"	"755.92"	"10.60"	"2"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf03165, Pf03166"	"4088"	"ENSG00000166949"	"SMAD3"	"A8K4B6; B7Z4Z5; B7Z6M9; B7Z9Q2; F5H383; hsa:4088; O09064; O09144; O14510; O35273; P84022; Q92940; Q93002; Q9GKR4"	"Ub-specific processing proteases; Formation of axial mesoderm; FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes; SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Signaling by NODAL; FOXO-mediated transcription of cell cycle genes; Downregulation of TGF-beta receptor signaling; Downregulation of SMAD2/3:SMAD4 transcriptional activity; Germ layer formation at gastrulation; Formation of definitive endoderm; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; RUNX3 regulates BCL2L11 (BIM) transcription; Signaling by Activin; SMAD2/3 Phosphorylation Motif Mutants in Cancer; TGFBR1 KD Mutants in Cancer; Interleukin-37 signaling; RUNX3 regulates CDKN1A transcription; NOTCH4 Intracellular Domain Regulates Transcription; SMAD4 MH2 Domain Mutants in Cancer; SMAD2/3 MH2 Domain Mutants in Cancer"	"Androgen receptor signaling pathway; Cell cycle; AGE/RAGE pathway; Adipogenesis; Endoderm differentiation; Mesodermal commitment pathway; Extracellular vesicle-mediated signaling in recipient cells; Mesodermal commitment pathway; Ovarian infertility; Hepatitis C and hepatocellular carcinoma; Hypothesized pathways in pathogenesis of cardiovascular disease; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition; Canonical and non-canonical TGF-B signaling; Chromosomal and microsatellite instability in colorectal cancer ; Epithelial to mesenchymal transition in colorectal cancer; Pancreatic adenocarcinoma pathway; Neovascularisation processes; Vitamin D in inflammatory diseases; Envelope proteins and their potential roles in EDMD physiopathology; Hippo signaling regulation pathways; Hepatitis B infection; TGF-beta receptor signaling in skeletal dysplasias; Overlap between signal transduction pathways contributing to LMNA laminopathies; Angiotensin II receptor type 1 pathway; SARS-CoV-2 innate immunity evasion and cell-specific immune response; Neuroinflammation and glutamatergic signaling; CCL18 signaling pathway; Progeria-associated lipodystrophy; GDNF signaling; Urotensin-II-mediated signaling pathway; A network map of Macrophage-stimulating protein (MSP) signaling; TGF-beta receptor signaling; DNA damage response (only ATM dependent)"	"55"	"0"	"63.6"	"25.2"	"61.0"	"39.4"	"45.1"	"50.4"	"42.4"	"73.5"	"132.9"	"370.7"	"550.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46779"	"60S ribosomal protein L28 OS=Homo sapiens OX=9606 GN=RPL28 PE=1 SV=3"	"0.000"	""	"19"	"3"	"8"	"3"	"137"	"15.7"	"12.02"	"1465.51"	"10.59"	"3"	"3"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01778"	"6158"	"ENSG00000108107"	"RPL28"	"B2R4A6; B4DEP9; C9JB50; E9PB24; G5E9L2; hsa:6158; P46779; Q6IAY0; Q96FX1; Q9BWQ0"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"958.3"	"352.3"	"807.4"	"806.4"	"835.7"	"1013.5"	"688.2"	"954.9"	"650.6"	"1326.5"	"1901.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P32929"	"Cystathionine gamma-lyase OS=Homo sapiens OX=9606 GN=CTH PE=1 SV=3"	"0.000"	""	"11"	"3"	"5"	"3"	"405"	"44.5"	"6.70"	"782.34"	"10.57"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf01053"	"1491"	"ENSG00000116761"	"CTH"	"B4E1R2; E9PDV0; hsa:1491; P32929; Q53FB3; Q53Y79; Q9H4W7; Q9H4W8"	"Degradation of cysteine and homocysteine; Metabolism of ingested SeMet, Sec, MeSec into H2Se; Cysteine formation from homocysteine"	"Selenium micronutrient network; Vitamin B12 metabolism; Folate metabolism; Trans-sulfuration pathway; Trans-sulfuration, one-carbon metabolism and related pathways; Amino acid metabolism; Methionine metabolism leading to sulfur amino acids and related disorders; Ferroptosis"	"11"	"0"	"189.3"	"83.8"	"178.3"	"152.1"	"142.5"	"176.7"	"137.5"	"168.7"	"141.2"	"229.8"	"352.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92900"	"Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2"	"0.000"	""	"3"	"3"	"5"	"3"	"1129"	"124.3"	"6.61"	"833.48"	"10.56"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09416, Pf13086, Pf13087, Pf18141"	"5976"	"ENSG00000005007"	"UPF1"	"hsa:5976; O00239; O43343; Q86Z25; Q92842; Q92900"	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Pathophysiological roles of DUX4 in FSHD1"	"3"	"0"	"225.3"	"108.0"	"201.1"	"173.3"	"169.9"	"231.5"	"198.2"	"281.9"	"250.3"	"500.4"	"777.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H6T3"	"RNA polymerase II-associated protein 3 OS=Homo sapiens OX=9606 GN=RPAP3 PE=1 SV=2"	"0.000"	""	"4"	"2"	"6"	"2"	"665"	"75.7"	"6.84"	"1176.41"	"10.56"	"2"	"2"	"other biological processes"	"cytosol;other cell component"	""	"Pf00515, Pf13176, Pf13181, Pf13877"	"79657"	"ENSG00000005175"	"RPAP3"	"B4DRW9; hsa:79657; Q6PHR5; Q9H6T3"	""	""	"0"	"0"	"77.0"	"28.5"	"72.5"	"55.8"	"65.0"	"90.6"	"69.0"	"105.8"	"82.6"	"154.0"	"356.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O75052"	"Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein OS=Homo sapiens OX=9606 GN=NOS1AP PE=1 SV=3"	""	""	"8"	"2"	"2"	"2"	"506"	"56.1"	"6.30"	""	"10.56"	""	"2"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00640"	"9722"	"ENSG00000198929"	"NOS1AP"	"B7ZLF5; hsa:9722; O43564; O75052; Q3T551; Q5VU95"	""	"Sudden infant death syndrome (SIDS) susceptibility pathways"	"1"	"0"	"67.2"	"32.9"	"75.2"	"67.7"	"65.0"	"75.9"	"51.7"	"89.7"	"122.6"	"644.2"	"1376.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKE5"	"TRAF2 and NCK-interacting protein kinase OS=Homo sapiens OX=9606 GN=TNIK PE=1 SV=1"	"0.000"	""	"4"	"4"	"6"	"1"	"1360"	"154.8"	"7.17"	"599.12"	"10.55"	"2"	"4"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00780"	"23043"	"ENSG00000154310"	"TNIK"	"A7E2A3; A8K4U1; D3DNQ6; hsa:23043; O60298; Q8WUY7; Q9UKD8; Q9UKD9; Q9UKE0; Q9UKE1; Q9UKE2; Q9UKE3; Q9UKE4; Q9UKE5"	"Oxidative Stress Induced Senescence"	"Hippo-YAP signaling; Pleural mesothelioma"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NI27"	"THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2"	"0.000"	""	"2"	"4"	"7"	"4"	"1593"	"182.7"	"8.44"	"915.06"	"10.53"	"3"	"4"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf11262, Pf11732, Pf16134"	"57187"	"ENSG00000125676"	"THOC2"	"A6NM50; hsa:57187; Q5JZ12; Q6IN92; Q8NI27; Q9H8I6"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	""	"3"	"0"	"564.3"	"184.2"	"453.4"	"445.4"	"453.4"	"517.2"	"362.2"	"486.1"	"270.9"	"1205.5"	"3683.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P56192"	"Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2"	"0.000"	""	"5"	"3"	"5"	"3"	"900"	"101.1"	"6.16"	"566.00"	"10.49"	"2"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00043, Pf00458, Pf09334, Pf18485, Pf19303"	"4141"	"ENSG00000166986"	"MARS1"	"B3KVK7; hsa:4141; P56192; Q14895; Q53H14; Q96A15; Q96BZ0; Q9NSE0"	"Cytosolic tRNA aminoacylation; Selenoamino acid metabolism"	""	"2"	"0"	"152.8"	"53.1"	"126.8"	"111.8"	"123.5"	"142.7"	"115.8"	"144.8"	"130.5"	"318.0"	"832.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92558"	"Wiskott-Aldrich syndrome protein family member 1 OS=Homo sapiens OX=9606 GN=WASF1 PE=1 SV=1"	"0.000"	""	"5"	"2"	"6"	"2"	"559"	"61.6"	"6.46"	"1284.99"	"10.48"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02205"	"8936"	"ENSG00000112290"	"WASF1"	"E1P5F2; hsa:8936; Q5SZK7; Q92558"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RAC1 GTPase cycle; RHO GTPases Activate WASPs and WAVEs; RAC3 GTPase cycle; VEGFA-VEGFR2 Pathway"	"VEGFA-VEGFR2 signaling; Regulation of actin cytoskeleton"	"8"	"0"	"28.5"	"15.7"	"26.4"	"21.3"	"24.0"	"29.7"	"21.6"	"37.4"	"34.6"	"134.9"	"289.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P84098"	"60S ribosomal protein L19 OS=Homo sapiens OX=9606 GN=RPL19 PE=1 SV=1"	"0.000"	""	"20"	"4"	"6"	"3"	"196"	"23.5"	"11.47"	"1123.16"	"10.47"	"3"	"3"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01280"	"6143"	"ENSG00000108298"	"RPL19"	"B2R4K2; hsa:6143; P14118; P22908; P84098; Q502Y6; Q7Z6E4"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"1"	"677.6"	"268.9"	"637.1"	"585.5"	"585.0"	"722.1"	"479.6"	"666.3"	"434.1"	"852.0"	"1070.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y4Y9"	"U6 snRNA-associated Sm-like protein LSm5 OS=Homo sapiens OX=9606 GN=LSM5 PE=1 SV=3"	""	""	"25"	"1"	"2"	"1"	"91"	"9.9"	"4.54"	""	"10.43"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01423"	"23658"	"ENSG00000106355"	"LSM5"	"hsa:23658; Q9Y4Y9"	"mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease"	""	"2"	"0"	"38.3"	"15.8"	"32.4"	"30.9"	"26.5"	"38.5"	"25.7"	"37.4"	"33.0"	"71.0"	"91.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NFJ9"	"Bardet-Biedl syndrome 1 protein OS=Homo sapiens OX=9606 GN=BBS1 PE=1 SV=1"	"0.000"	""	"5"	"2"	"4"	"2"	"593"	"65.0"	"7.93"	"1149.06"	"10.42"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf14779"	"582"	"ENSG00000174483"	"BBS1"	"hsa:582; Q32MM9; Q32MN0; Q8NFJ9; Q96SN4"	"BBSome-mediated cargo-targeting to cilium"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies; Bardet-Biedl syndrome"	"6"	"0"	"14.3"	"2.9"	"7.9"	"8.0"	"13.1"	"10.9"	"13.4"	"33.5"	"47.4"	"163.6"	"286.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43809"	"Cleavage and polyadenylation specificity factor subunit 5 OS=Homo sapiens OX=9606 GN=NUDT21 PE=1 SV=1"	"0.000"	""	"16"	"4"	"7"	"4"	"227"	"26.2"	"8.82"	"1240.82"	"10.40"	"4"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13869"	"11051"	"ENSG00000167005"	"NUDT21"	"hsa:11051; O43809; Q6IB85; Q6NE84"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"mRNA processing"	"5"	"0"	"1525.1"	"471.8"	"932.4"	"764.8"	"871.0"	"1095.2"	"1063.5"	"1691.9"	"1280.2"	"1571.1"	"2541.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UK45"	"U6 snRNA-associated Sm-like protein LSm7 OS=Homo sapiens OX=9606 GN=LSM7 PE=1 SV=1"	"0.000"	""	"40"	"3"	"6"	"3"	"103"	"11.6"	"5.27"	"848.33"	"10.40"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	"51690"	"ENSG00000130332"	"LSM7"	"hsa:51690; Q9UK45"	"mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease"	"mRNA processing"	"3"	"0"	"763.0"	"303.4"	"551.8"	"423.5"	"566.4"	"608.5"	"522.8"	"680.8"	"517.6"	"882.8"	"1777.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P21127"	"Cyclin-dependent kinase 11B OS=Homo sapiens OX=9606 GN=CDK11B PE=1 SV=4"	"0.000"	""	"6"	"5"	"9"	"5"	"795"	"92.6"	"5.54"	"1469.77"	"10.34"	"4"	"3"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"984"	"ENSG00000248333"	"CDK11B"	"B7ZVY7; hsa:984; J3KTL7; J3QR29; J3QR44; O95265; P21127; Q12817; Q12818; Q12819; Q12820; Q12822; Q8N530; Q9NZS5; Q9UBJ0; Q9UBQ1; Q9UBR0; Q9UNY2; Q9UP57; Q9UP58; Q9UP59"	"Recruitment of mitotic centrosome proteins and complexes"	"1p36 copy number variation syndrome"	"2"	"0"	"537.1"	"204.0"	"440.0"	"385.0"	"406.9"	"503.9"	"403.3"	"567.6"	"430.7"	"807.0"	"1325.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q04760"	"Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4"	"0.000"	""	"30"	"4"	"8"	"4"	"184"	"20.8"	"5.31"	"1294.30"	"10.31"	"4"	"4"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00903"	"2739"	"ENSG00000124767"	"GLO1"	"B2R6P7; B4DDV0; hsa:2739; P78375; Q04760; Q59EL0; Q5TZW3; Q96FC0; Q96J41"	"Pyruvate metabolism"	""	"1"	"0"	"368.1"	"141.5"	"216.1"	"143.7"	"232.6"	"221.3"	"267.5"	"250.9"	"311.7"	"421.5"	"756.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14910"	"Protein lin-7 homolog A OS=Homo sapiens OX=9606 GN=LIN7A PE=1 SV=2"	"0.000"	""	"16"	"5"	"10"	"1"	"233"	"26.0"	"8.72"	"1629.13"	"10.28"	"5"	"3"	"cell-cell signaling;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00595, Pf02828"	"8825"	"ENSG00000111052"	"LIN7A"	"A4FTY3; hsa:8825; O14910; Q147W1; Q6LES3; Q7LDS4"	"Assembly and cell surface presentation of NMDA receptors; Neurexins and neuroligins; Dopamine Neurotransmitter Release Cycle"	""	"3"	"0"	"64.6"	"34.7"	"59.9"	"52.9"	"69.6"	"80.0"	"62.3"	"76.7"	"76.3"	"174.2"	"366.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95218"	"Zinc finger Ran-binding domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ZRANB2 PE=1 SV=2"	"0.000"	""	"6"	"2"	"6"	"2"	"330"	"37.4"	"10.01"	"1259.94"	"10.23"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00641"	"9406"	"ENSG00000132485"	"ZRANB2"	"D3DQ75; hsa:9406; O95218; Q53GS3; Q59F92; Q5VV33; Q5VV34; Q8IXN6; Q9UP63"	""	""	"0"	"0"	"470.9"	"214.6"	"451.0"	"473.5"	"461.0"	"615.4"	"568.4"	"872.3"	"531.9"	"620.4"	"836.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WWH5"	"Probable tRNA pseudouridine synthase 1 OS=Homo sapiens OX=9606 GN=TRUB1 PE=1 SV=1"	"0.000"	""	"11"	"3"	"5"	"3"	"349"	"37.2"	"8.25"	"736.05"	"10.22"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01509"	"142940"	"ENSG00000165832"	"TRUB1"	"B2R716; hsa:142940; Q53ES2; Q8WWH5"	""	""	"0"	"0"	"50.1"	"23.9"	"52.2"	"45.4"	"55.9"	"56.6"	"43.4"	"74.9"	"67.1"	"221.1"	"507.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P31483"	"Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3"	"0.000"	""	"7"	"3"	"8"	"1"	"386"	"42.9"	"7.74"	"1103.27"	"10.22"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"7072"	"ENSG00000116001"	"TIA1"	"hsa:7072; P31483; Q53SS9; Q96B58"	"FGFR2 alternative splicing"	""	"1"	"0"	"144.3"	"82.3"	"147.2"	"105.5"	"114.1"	"128.9"	"103.5"	"146.2"	"120.4"	"177.6"	"232.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62195"	"26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1"	"0.000"	""	"11"	"3"	"5"	"3"	"406"	"45.6"	"7.55"	"807.03"	"10.20"	"2"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00004, Pf16450, Pf17862"	"5705"	"ENSG00000087191"	"PSMC5"	"A8K3Z3; A8K763; hsa:5705; O35051; O43208; P47210; P52915; P52916; P62195"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Pregnane X receptor pathway; Nuclear receptors meta-pathway; Alzheimer's disease"	"65"	"0"	"61.4"	"17.0"	"44.6"	"47.1"	"62.7"	"56.1"	"43.0"	"61.5"	"49.0"	"75.5"	"124.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61313"	"60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2"	"0.000"	""	"14"	"3"	"7"	"3"	"204"	"24.1"	"11.62"	"1485.79"	"10.19"	"3"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00827"	"6138"	"ENSG00000174748"	"RPL15"	"hsa:6138; P39030; P41051; P61313; Q5U0C0; Q642I1; Q6IPX6; Q8WYP2; Q96C44; Q9H2E5"	"Major pathway of rRNA processing in the nucleolus and cytosol; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"454.7"	"194.4"	"348.8"	"285.8"	"304.9"	"418.7"	"315.6"	"408.0"	"316.9"	"520.1"	"648.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P20248"	"Cyclin-A2 OS=Homo sapiens OX=9606 GN=CCNA2 PE=1 SV=2"	"0.000"	""	"6"	"2"	"4"	"2"	"432"	"48.5"	"6.54"	"1100.12"	"10.17"	"2"	"2"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00134, Pf02984, Pf16500"	"890"	"ENSG00000145386"	"CCNA2"	"A8K7B6; hsa:890; P20248; Q2M3U6; Q4W5P4; Q6LER8"	"TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; Regulation of TP53 Degradation; SCF(Skp2)-mediated degradation of p27/p21; Regulation of TP53 Activity through Phosphorylation; G2 Phase; Telomere Extension By Telomerase; Regulation of APC/C activators between G1/S and early anaphase; Senescence-Associated Secretory Phenotype (SASP); Processing of DNA double-strand break ends; DNA Damage/Telomere Stress Induced Senescence; p53-Dependent G1 DNA Damage Response; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1; Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes"	"AMP-activated protein kinase signaling; Cell cycle; Retinoblastoma gene in cancer; IL-18 signaling pathway"	"24"	"0"	"111.1"	"50.6"	"103.2"	"89.2"	"87.5"	"100.9"	"83.5"	"107.3"	"83.6"	"254.6"	"650.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15019"	"Septin-2 OS=Homo sapiens OX=9606 GN=SEPTIN2 PE=1 SV=1"	"0.000"	""	"13"	"4"	"6"	"4"	"361"	"41.5"	"6.60"	"1139.90"	"10.17"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00735"	"4735"	"ENSG00000168385"	"SEPTIN2"	"B4DGE8; hsa:4735; Q14132; Q15019; Q53QU3; Q8IUK9; Q96CB0"	"Anchoring of the basal body to the plasma membrane"	"2q37 copy number variation syndrome"	"2"	"0"	"425.1"	"161.1"	"359.5"	"289.0"	"378.9"	"421.6"	"318.7"	"468.0"	"401.1"	"961.1"	"2285.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3E5"	"Peptidyl-tRNA hydrolase 2, mitochondrial OS=Homo sapiens OX=9606 GN=PTRH2 PE=1 SV=1"	"0.000"	""	"21"	"2"	"3"	"2"	"179"	"19.2"	"8.73"	"374.28"	"10.17"	"1"	"2"	"other biological processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf01981"	"51651"	"ENSG00000141378"	"PTRH2"	"B3KUY4; hsa:51651; Q9NTE5; Q9Y3E5"	"Ub-specific processing proteases"	"Apoptosis modulation and signaling"	"2"	"0"	"33.3"	"11.4"	"29.7"	"22.1"	"31.0"	"34.9"	"33.8"	"46.7"	"35.0"	"123.6"	"251.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53041"	"Serine/threonine-protein phosphatase 5 OS=Homo sapiens OX=9606 GN=PPP5C PE=1 SV=1"	"0.000"	""	"10"	"3"	"4"	"3"	"499"	"56.8"	"6.28"	"356.96"	"10.16"	"1"	"3"	"cell cycle OR cell proliferation;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00149, Pf00515, Pf08321"	"5536"	"ENSG00000011485"	"PPP5C"	"hsa:5536; P53041; Q16722; Q53XV2"	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Negative regulation of MAPK pathway; ESR-mediated signaling"	"MAPK signaling pathway; ATM signaling in development and disease"	"5"	"0"	"65.4"	"27.0"	"47.3"	"39.3"	"53.4"	"47.9"	"53.9"	"64.0"	"87.9"	"233.3"	"999.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19525"	"Interferon-induced, double-stranded RNA-activated protein kinase OS=Homo sapiens OX=9606 GN=EIF2AK2 PE=1 SV=2"	"0.000"	""	"5"	"2"	"6"	"2"	"551"	"62.1"	"8.40"	"1137.45"	"10.15"	"2"	"2"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;kinase activity;other molecular function"	"Pf00035, Pf00069"	"5610"	"ENSG00000055332"	"EIF2AK2"	"A8K3P0; D6W584; E9PC80; hsa:5610; P19525; Q52M43; Q7Z6F6; Q9UIR4"	"ISG15 antiviral mechanism; Interferon alpha/beta signaling; Inhibition of PKR"	"Translation factors; Alzheimer's disease and miRNA effects; Ebola virus infection in host; Measles virus infection; Type I interferon induction and signaling during SARS-CoV-2 infection; Host-pathogen interaction of human coronaviruses - interferon induction; Alzheimer's disease; Roles of ceramides in development of insulin resistance; Type II interferon signaling"	"12"	"0"	"69.8"	"32.7"	"59.5"	"47.4"	"57.8"	"73.7"	"59.7"	"90.6"	"86.2"	"137.1"	"329.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51970"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 OS=Homo sapiens OX=9606 GN=NDUFA8 PE=1 SV=3"	"0.000"	""	"34"	"6"	"10"	"6"	"172"	"20.1"	"7.65"	"2583.74"	"10.15"	"6"	"3"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf06747"	"4702"	"ENSG00000119421"	"NDUFA8"	"B1AM93; hsa:4702; P51970; Q9Y6N0"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"5"	"0"	"1229.0"	"582.9"	"1165.6"	"1019.9"	"1111.7"	"1263.9"	"957.2"	"1201.9"	"879.2"	"1824.9"	"3539.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6NZY4"	"Zinc finger CCHC domain-containing protein 8 OS=Homo sapiens OX=9606 GN=ZCCHC8 PE=1 SV=2"	"0.000"	""	"6"	"3"	"6"	"3"	"707"	"78.5"	"4.87"	"1062.87"	"10.14"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00098, Pf04046"	"55596"	"ENSG00000033030"	"ZCCHC8"	"hsa:55596; Q6NZY4; Q7L2P6; Q8N2K5; Q96SK7; Q9NSS2; Q9NSS3"	""	""	"0"	"0"	"201.5"	"118.7"	"186.2"	"141.4"	"148.4"	"173.6"	"126.6"	"176.0"	"145.1"	"227.8"	"295.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q29RF7"	"Sister chromatid cohesion protein PDS5 homolog A OS=Homo sapiens OX=9606 GN=PDS5A PE=1 SV=1"	"0.000"	""	"3"	"3"	"6"	"2"	"1337"	"150.7"	"7.91"	"1004.81"	"10.09"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	""	"Pf20168"	"23244"	"ENSG00000121892"	"PDS5A"	"hsa:23244; Q29RF7; Q2TTR5; Q68DF7; Q8N7J4; Q8NG14; Q9Y4D4"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"Cohesin complex - Cornelia de Lange syndrome; 10q22q23 copy number variation"	"6"	"0"	"27.8"	"9.2"	"21.3"	"18.4"	"15.0"	"23.9"	"22.1"	"23.0"	"32.1"	"56.1"	"146.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95299"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFA10 PE=1 SV=1"	"0.000"	""	"11"	"3"	"6"	"3"	"355"	"40.7"	"8.48"	"1001.08"	"10.07"	"3"	"3"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion;other cell component"	"transporter activity"	"Pf01712"	"4705"	"ENSG00000130414"	"NDUFA10"	"hsa:4705; O95299; Q8WXC9"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; 2q37 copy number variation syndrome; Oxidative phosphorylation"	"6"	"0"	"95.2"	"39.3"	"92.4"	"88.1"	"86.8"	"102.8"	"79.8"	"103.7"	"64.5"	"120.5"	"176.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y697"	"Cysteine desulfurase, mitochondrial OS=Homo sapiens OX=9606 GN=NFS1 PE=1 SV=3"	"0.000"	""	"10"	"3"	"6"	"3"	"457"	"50.2"	"8.31"	"1168.41"	"10.03"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf00266"	"9054"	"ENSG00000244005"	"NFS1"	"B3KMA5; B4DXK9; E1P5R8; F5GYK5; hsa:9054; Q6P0L8; Q9NTZ5; Q9Y481; Q9Y697"	""	"Iron-sulfur cluster biogenesis"	"1"	"0"	"40.8"	"21.1"	"40.4"	"33.6"	"36.9"	"39.1"	"28.5"	"42.4"	"51.2"	"110.5"	"180.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52701"	"DNA mismatch repair protein Msh6 OS=Homo sapiens OX=9606 GN=MSH6 PE=1 SV=2"	"0.000"	""	"3"	"3"	"6"	"3"	"1360"	"152.7"	"6.90"	"1123.63"	"10.00"	"3"	"3"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00488, Pf00855, Pf01624, Pf05188, Pf05190, Pf05192"	"2956"	"ENSG00000116062"	"MSH6"	"B4DF41; B4E3I4; F5H2F9; hsa:2956; O43706; O43917; P52701; Q8TCX4; Q9BTB5"	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Defective Mismatch Repair Associated With MSH2; Defective Mismatch Repair Associated With MSH6"	"Glioblastoma signaling pathways; Retinoblastoma gene in cancer; Chromosomal and microsatellite instability in colorectal cancer ; DNA repair pathways, full network; DNA mismatch repair"	"8"	"0"	"153.1"	"61.4"	"146.6"	"128.1"	"152.6"	"162.8"	"121.9"	"189.7"	"140.1"	"274.8"	"499.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00422"	"Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1"	"0.000"	""	"35"	"5"	"7"	"5"	"153"	"17.6"	"9.35"	"1103.65"	"9.92"	"4"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf06487"	"10284"	"ENSG00000150459"	"SAP18"	"B2R494; hsa:10284; O00422; Q2TTR4; Q6IAW9; Q8N606; Q9UF14; X6RAL5"	"Potential therapeutics for SARS; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; mRNA Splicing - Major Pathway"	"Hedgehog signaling pathway"	"5"	"0"	"1506.5"	"520.3"	"916.5"	"807.0"	"897.4"	"1072.7"	"834.9"	"1079.5"	"786.3"	"2518.0"	"4933.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULP9"	"TBC1 domain family member 24 OS=Homo sapiens OX=9606 GN=TBC1D24 PE=1 SV=2"	"0.000"	""	"3"	"2"	"5"	"2"	"559"	"62.9"	"7.36"	"567.96"	"9.90"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;other cell component"	"enzyme regulator activity"	"Pf00566, Pf07534"	"57465"	"ENSG00000162065"	"TBC1D24"	"A0JNW3; B9A6M6; hsa:57465; Q2KJ08; Q9ULP9"	"TBC/RABGAPs"	""	"1"	"0"	"93.4"	"33.2"	"69.8"	"72.3"	"72.7"	"73.5"	"72.3"	"178.6"	"336.6"	"1092.3"	"1620.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61353"	"60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2"	"0.000"	""	"24"	"4"	"8"	"4"	"136"	"15.8"	"10.56"	"1130.67"	"9.90"	"4"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00467, Pf01777"	"6155"	"ENSG00000131469"	"RPL27"	"hsa:6155; P08526; P61353; Q4G0A9"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"15"	"0"	"1017.4"	"386.1"	"808.2"	"676.5"	"762.8"	"884.3"	"672.6"	"935.3"	"689.4"	"1129.3"	"1317.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96BJ3"	"Axin interactor, dorsalization-associated protein OS=Homo sapiens OX=9606 GN=AIDA PE=1 SV=1"	"0.000"	""	"12"	"3"	"5"	"3"	"306"	"35.0"	"6.55"	"712.43"	"9.90"	"2"	"3"	"developmental processes;other biological processes"	"other membranes;other cell component"	"other molecular function"	"Pf08910, Pf14186"	"64853"	"ENSG00000186063"	"AIDA"	"A8K1F0; hsa:64853; Q49A81; Q5JRA4; Q658P1; Q96BJ3; Q9H9E8"	""	""	"0"	"0"	"80.1"	"35.6"	"63.5"	"51.7"	"73.2"	"76.5"	"65.6"	"88.6"	"80.6"	"424.9"	"710.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y265"	"RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1"	"0.000"	""	"8"	"3"	"6"	"3"	"456"	"50.2"	"6.42"	"1169.83"	"9.88"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf06068, Pf17856"	"8607"	"ENSG00000175792; ENSG00000284901"	"RUVBL1"	"B2R5S0; hsa:8607; P82276; Q1KMR0; Q53HK5; Q53HL7; Q53Y27; Q9BSX9; Q9Y265"	"Ub-specific processing proteases; Deposition of new CENPA-containing nucleosomes at the centromere; Formation of the beta-catenin:TCF transactivating complex; HATs acetylate histones; DNA Damage Recognition in GG-NER; UCH proteinases; Telomere Extension By Telomerase"	"Gastric cancer network 1; lncRNA in canonical Wnt signaling and colorectal cancer"	"9"	"0"	"176.7"	"64.8"	"152.8"	"115.3"	"129.3"	"167.1"	"138.4"	"165.6"	"136.6"	"244.6"	"455.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7RTP6"	"[F-actin]-monooxygenase MICAL3 OS=Homo sapiens OX=9606 GN=MICAL3 PE=1 SV=2"	"0.000"	""	"2"	"4"	"6"	"4"	"2002"	"224.2"	"5.55"	"591.37"	"9.87"	"2"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00412, Pf01494, Pf12130"	"57553"	"ENSG00000243156"	"MICAL3"	"B2RXJ5; E9PEF0; hsa:57553; O94909; Q5U4P4; Q6ICK4; Q7RTP6; Q96DF2; Q9P2I3"	""	""	"0"	"0"	"68.4"	"33.1"	"54.9"	"52.4"	"62.4"	"66.8"	"60.2"	"102.5"	"93.0"	"277.4"	"394.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02880"	"DNA topoisomerase 2-beta OS=Homo sapiens OX=9606 GN=TOP2B PE=1 SV=3"	"0.000"	""	"3"	"4"	"6"	"3"	"1626"	"183.2"	"8.00"	"1041.76"	"9.85"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00204, Pf00521, Pf01751, Pf02518, Pf08070, Pf16898"	"7155"	"ENSG00000077097"	"TOP2B"	"hsa:7155; Q02880; Q13600; Q9UMG8; Q9UQP8"	"SUMOylation of DNA replication proteins"	""	"1"	"0"	"141.8"	"62.1"	"100.9"	"99.0"	"112.2"	"125.0"	"97.3"	"148.6"	"123.0"	"197.1"	"351.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15020"	"Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1"	"0.000"	""	"4"	"3"	"4"	"3"	"963"	"109.9"	"5.57"	"545.99"	"9.80"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00076, Pf05391, Pf16605"	"9733"	"ENSG00000075856"	"SART3"	"A8K2E4; B7ZKM0; hsa:9733; Q15020; Q2M2H0; Q58F06; Q8IUS1; Q96J95"	""	""	"0"	"0"	"291.6"	"121.4"	"289.6"	"224.4"	"272.9"	"294.1"	"187.9"	"283.5"	"169.9"	"369.5"	"499.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55735"	"Protein SEC13 homolog OS=Homo sapiens OX=9606 GN=SEC13 PE=1 SV=3"	"0.000"	""	"8"	"2"	"4"	"2"	"322"	"35.5"	"5.48"	"703.93"	"9.78"	"2"	"2"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00400"	"6396"	"ENSG00000157020"	"SEC13"	"A8MV37; B4DXJ1; hsa:6396; P55735; Q5BJF0; Q9BRM6; Q9BUG7"	"COPII-mediated vesicle transport; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; RHO GTPases Activate Formins; snRNP Assembly; Separation of Sister Chromatids; Viral Messenger RNA Synthesis; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; HCMV Late Events; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; HCMV Early Events; EML4 and NUDC in mitotic spindle formation; Amino acids regulate mTORC1; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Postmitotic nuclear pore complex (NPC) reformation"	"Sterol regulatory element-binding proteins (SREBP) signaling"	"40"	"0"	"343.3"	"108.5"	"425.3"	"377.0"	"392.7"	"533.7"	"338.8"	"381.4"	"221.1"	"617.8"	"968.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IV48"	"3'-5' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=ERI1 PE=1 SV=3"	"0.000"	""	"9"	"3"	"5"	"3"	"349"	"40.0"	"6.70"	"786.78"	"9.77"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00929, Pf02037"	"90459"	"ENSG00000104626"	"ERI1"	"A8K4U7; hsa:90459; Q8IV48; Q9NSX3"	"Major pathway of rRNA processing in the nucleolus and cytosol"	"exRNA mechanism of action and biogenesis; 8p23.1 copy number variation syndrome; 4p16.3 copy number variation"	"4"	"0"	"120.5"	"55.8"	"100.6"	"100.2"	"88.5"	"91.5"	"94.7"	"123.0"	"228.0"	"1367.4"	"2028.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBC2"	"Epidermal growth factor receptor substrate 15-like 1 OS=Homo sapiens OX=9606 GN=EPS15L1 PE=1 SV=1"	"0.001"	""	"4"	"2"	"4"	"2"	"864"	"94.2"	"5.11"	"272.18"	"9.77"	"1"	"2"	"transport"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf12763"	"58513"	"ENSG00000127527"	"EPS15L1"	"A2RRF3; A5PL29; B4DKA3; hsa:58513; Q9UBC2"	"Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation"	"EGF/EGFR signaling pathway"	"4"	"0"	"15.1"	"5.1"	"15.3"	"12.3"	"11.0"	"22.1"	"12.0"	"22.0"	"16.3"	"40.0"	"51.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKK9"	"ADP-sugar pyrophosphatase OS=Homo sapiens OX=9606 GN=NUDT5 PE=1 SV=1"	"0.000"	""	"20"	"4"	"6"	"4"	"219"	"24.3"	"4.94"	"1303.93"	"9.76"	"3"	"3"	"cell organization and biogenesis;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00293"	"11164"	"ENSG00000165609"	"NUDT5"	"A8K516; hsa:11164; Q6IAG0; Q9UH49; Q9UKK9"	"Phosphate bond hydrolysis by NUDT proteins"	""	"1"	"0"	"556.0"	"209.3"	"494.9"	"486.5"	"546.2"	"579.1"	"467.1"	"594.4"	"490.4"	"835.0"	"1564.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N1G4"	"Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1"	"0.000"	""	"8"	"3"	"5"	"3"	"583"	"63.4"	"8.28"	"864.66"	"9.74"	"2"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	""	"other molecular function"	"Pf00560, Pf03483, Pf12799"	"57470"	"ENSG00000130764"	"LRRC47"	"hsa:57470; Q8N1G4; Q9ULN5"	""	""	"0"	"0"	"244.7"	"89.3"	"195.5"	"153.7"	"179.7"	"242.7"	"160.8"	"226.4"	"191.4"	"384.5"	"798.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13595"	"Transformer-2 protein homolog alpha OS=Homo sapiens OX=9606 GN=TRA2A PE=1 SV=1"	"0.000"	""	"10"	"3"	"8"	"3"	"282"	"32.7"	"11.27"	"1516.81"	"9.74"	"3"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00076"	"29896"	"ENSG00000164548"	"TRA2A"	"B4DQI6; B4DUA9; E9PD75; hsa:29896; Q13595"	""	"Orexin receptor pathway"	"1"	"0"	"611.0"	"152.0"	"272.0"	"248.9"	"309.5"	"293.6"	"292.9"	"352.1"	"387.1"	"689.4"	"1398.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O15143"	"Actin-related protein 2/3 complex subunit 1B OS=Homo sapiens OX=9606 GN=ARPC1B PE=1 SV=3"	""	""	"10"	"2"	"2"	"1"	"372"	"40.9"	"8.35"	""	"9.71"	""	"2"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400"	"10095"	"ENSG00000130429"	"ARPC1B"	"hsa:10095; O15143; Q9BU00"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; EPHB-mediated forward signaling"	"Pathogenic Escherichia coli infection; Microglia pathogen phagocytosis pathway"	"6"	"0"	"18.1"	"8.4"	"15.7"	"10.0"	"14.1"	"17.5"	"14.7"	"27.9"	"13.5"	"48.7"	"140.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NX63"	"MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1"	"0.000"	""	"12"	"3"	"6"	"3"	"227"	"26.1"	"8.28"	"1077.13"	"9.70"	"3"	"3"	"cell organization and biogenesis"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf05300"	"54927"	"ENSG00000106554"	"CHCHD3"	"hsa:54927; Q9NX63"	"Cristae formation; Mitochondrial protein import"	""	"2"	"0"	"1240.5"	"208.3"	"400.6"	"307.1"	"521.1"	"483.4"	"466.5"	"611.1"	"515.0"	"1042.9"	"2250.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L5N1"	"COP9 signalosome complex subunit 6 OS=Homo sapiens OX=9606 GN=COPS6 PE=1 SV=1"	"0.000"	""	"11"	"3"	"4"	"3"	"327"	"36.1"	"5.73"	"345.37"	"9.70"	"1"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf01398, Pf13012"	"10980"	"ENSG00000168090"	"COPS6"	"A4D2A3; hsa:10980; O15387; Q7L5N1"	"Neddylation; Formation of TC-NER Pre-Incision Complex; Cargo recognition for clathrin-mediated endocytosis; DNA Damage Recognition in GG-NER"	"Nucleotide-binding oligomerization domain (NOD) pathway; Ciliary landscape"	"6"	"0"	"95.9"	"40.0"	"81.6"	"71.1"	"64.0"	"138.1"	"195.2"	"424.3"	"360.8"	"907.7"	"3492.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15691"	"Microtubule-associated protein RP/EB family member 1 OS=Homo sapiens OX=9606 GN=MAPRE1 PE=1 SV=3"	"0.000"	""	"24"	"4"	"6"	"4"	"268"	"30.0"	"5.14"	"1120.06"	"9.66"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf03271"	"22919"	"ENSG00000101367"	"MAPRE1"	"B2R6I7; E1P5M8; hsa:22919; Q15691; Q3KQS8"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Anchoring of the basal body to the plasma membrane; The role of GTSE1 in G2/M progression after G2 checkpoint; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; AURKA Activation by TPX2"	"Microtubule cytoskeleton regulation"	"15"	"0"	"418.7"	"190.6"	"410.2"	"385.8"	"421.7"	"496.7"	"373.1"	"496.9"	"360.0"	"640.4"	"849.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50395"	"Rab GDP dissociation inhibitor beta OS=Homo sapiens OX=9606 GN=GDI2 PE=1 SV=2"	"0.000"	""	"8"	"3"	"6"	"3"	"445"	"50.6"	"6.47"	"897.12"	"9.63"	"3"	"3"	"transport;signal transduction;other biological processes"	"non-structural extracellular;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00996"	"2665"	"ENSG00000057608"	"GDI2"	"hsa:2665; O43928; P50395; Q5SX88; Q9UQM6"	"Neutrophil degranulation; RAB GEFs exchange GTP for GDP on RABs"	""	"2"	"0"	"75.1"	"49.1"	"63.1"	"55.1"	"65.7"	"62.3"	"57.5"	"75.8"	"83.2"	"166.1"	"358.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43813"	"Glutathione S-transferase LANCL1 OS=Homo sapiens OX=9606 GN=LANCL1 PE=1 SV=1"	"0.000"	""	"9"	"3"	"6"	"3"	"399"	"45.3"	"7.75"	"1105.67"	"9.61"	"3"	"3"	"other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf05147"	"10314"	"ENSG00000115365"	"LANCL1"	"hsa:10314; O43813"	""	""	"0"	"0"	"276.5"	"123.3"	"220.6"	"204.1"	"218.1"	"263.5"	"212.4"	"295.0"	"249.4"	"414.9"	"625.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UQB8"	"Brain-specific angiogenesis inhibitor 1-associated protein 2 OS=Homo sapiens OX=9606 GN=BAIAP2 PE=1 SV=1"	"0.000"	""	"5"	"2"	"4"	"2"	"552"	"60.8"	"8.90"	"1104.17"	"9.57"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf07653, Pf08397"	"10458"	"ENSG00000175866"	"BAIAP2"	"hsa:10458; O43858; Q53HB1; Q86WC1; Q8N5C0; Q96CR7; Q9UBR3; Q9UQ43; Q9UQB8"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; CDC42 GTPase cycle; RAC1 GTPase cycle; RAC3 GTPase cycle; VEGFA-VEGFR2 Pathway"	"Regulation of actin cytoskeleton"	"8"	"0"	"109.1"	"44.8"	"88.9"	"76.9"	"84.6"	"99.9"	"61.4"	"109.4"	"103.5"	"796.8"	"1052.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NQ50"	"39S ribosomal protein L40, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL40 PE=1 SV=1"	"0.000"	""	"16"	"2"	"4"	"2"	"206"	"24.5"	"9.63"	"1131.79"	"9.57"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	""	"Pf09812"	"64976"	"ENSG00000185608"	"MRPL40"	"B3KVZ7; hsa:64976; O95134; Q9NQ50"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"22q11.2 copy number variation syndrome"	"4"	"0"	"44.0"	"23.6"	"41.4"	"37.4"	"37.2"	"46.3"	"36.2"	"42.9"	"43.6"	"113.1"	"172.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P00338"	"L-lactate dehydrogenase A chain OS=Homo sapiens OX=9606 GN=LDHA PE=1 SV=2"	"0.000"	""	"8"	"3"	"8"	"3"	"332"	"36.7"	"8.27"	"1227.98"	"9.54"	"3"	"3"	"other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00056, Pf02866"	"3939"	"ENSG00000134333; ENSG00000288299"	"LDHA"	"B4DKQ2; B7Z5E3; D3DQY3; F8W819; hsa:3939; P00338; Q53G53; Q6IBM7; Q6ZNV1; Q9UDE8; Q9UDE9"	"Pyruvate metabolism"	"Cori cycle; HIF1A and PPARG regulation of glycolysis; Photodynamic therapy-induced HIF-1 survival signaling; VEGFA-VEGFR2 signaling; Amino acid metabolism; Clear cell renal cell carcinoma pathways; PI3K/AKT/mTOR - vitamin D3 signaling; Metabolic reprogramming in colon cancer; Aerobic glycolysis; Glycolysis in senescence; Orexin receptor pathway; CCL18 signaling pathway; Glucose metabolism in triple-negative breast cancer cells; Warburg effect modulated by deubiquitinating enzymes and their substrates; Lactate shuttle in glial cells; Glycolysis and gluconeogenesis; A network map of Macrophage-stimulating protein (MSP) signaling; Metabolic Epileptic Disorders"	"19"	"0"	"277.3"	"89.5"	"186.3"	"124.3"	"177.8"	"190.0"	"183.2"	"210.8"	"257.3"	"405.5"	"761.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50914"	"60S ribosomal protein L14 OS=Homo sapiens OX=9606 GN=RPL14 PE=1 SV=4"	"0.000"	""	"19"	"4"	"7"	"4"	"215"	"23.4"	"10.93"	"1309.79"	"9.53"	"4"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01929"	"9045"	"ENSG00000188846"	"RPL14"	"hsa:9045; P50914; Q45RF0; Q53G20; Q8TBD5; Q8WUT0; Q92579; Q96GR0; Q9BSB8; Q9BW65; Q9BYF6"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"542.5"	"219.9"	"498.0"	"433.6"	"478.0"	"576.4"	"376.7"	"525.2"	"369.3"	"644.7"	"907.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30050"	"60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1"	"0.000"	""	"24"	"4"	"8"	"4"	"165"	"17.8"	"9.42"	"1693.52"	"9.49"	"4"	"3"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00298, Pf03946"	"6136"	"ENSG00000197958"	"RPL12"	"hsa:6136; P30050; Q5VVV2; Q6PB27"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"1047.5"	"383.6"	"798.6"	"706.5"	"816.7"	"994.0"	"666.1"	"943.6"	"692.5"	"1233.2"	"1785.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13952"	"Nuclear transcription factor Y subunit gamma OS=Homo sapiens OX=9606 GN=NFYC PE=1 SV=3"	"0.000"	""	"9"	"3"	"5"	"3"	"458"	"50.3"	"6.10"	"703.88"	"9.49"	"2"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125"	"4802"	"ENSG00000066136"	"NFYC"	"B4DUS6; B4DW63; D3DPV9; F8VWM3; hsa:4802; Q13952; Q59GY4; Q5T6K8; Q5T6K9; Q5T6L1; Q5TZR6; Q92869; Q9HBX1; Q9NXB5; Q9UM67; Q9UML0; Q9UMT7"	"PPARA activates gene expression; Activation of gene expression by SREBF (SREBP); FOXO-mediated transcription of cell death genes; ATF4 activates genes in response to endoplasmic reticulum  stress; ATF6 (ATF6-alpha) activates chaperone genes"	""	"5"	"0"	"212.6"	"100.6"	"173.2"	"133.1"	"191.5"	"193.9"	"151.1"	"173.1"	"165.9"	"291.4"	"471.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09234"	"U1 small nuclear ribonucleoprotein C OS=Homo sapiens OX=9606 GN=SNRPC PE=1 SV=1"	"0.000"	""	"13"	"2"	"5"	"2"	"159"	"17.4"	"9.67"	"770.22"	"9.47"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf06220"	"6631"	"ENSG00000124562"	"SNRPC"	"hsa:6631; P09234; Q5TAL3"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"982.2"	"200.7"	"500.8"	"392.9"	"564.1"	"599.6"	"395.0"	"528.3"	"388.1"	"686.3"	"1258.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95777"	"U6 snRNA-associated Sm-like protein LSm8 OS=Homo sapiens OX=9606 GN=LSM8 PE=1 SV=3"	"0.000"	""	"30"	"2"	"4"	"2"	"96"	"10.4"	"4.48"	"954.34"	"9.45"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	"51691"	"ENSG00000128534"	"LSM8"	"hsa:51691; O95777"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"226.6"	"72.4"	"123.1"	"95.5"	"134.4"	"118.4"	"100.4"	"135.0"	"141.9"	"188.5"	"342.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11234"	"Ras-related protein Ral-B OS=Homo sapiens OX=9606 GN=RALB PE=1 SV=1"	"0.000"	""	"15"	"3"	"6"	"2"	"206"	"23.4"	"6.62"	"1018.70"	"9.42"	"3"	"3"	"cell cycle OR cell proliferation;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00071"	"5899"	"ENSG00000144118"	"RALB"	"B4E040; hsa:5899; P11234; Q53T32; Q6ZS74"	"p38MAPK events"	"Chromosomal and microsatellite instability in colorectal cancer ; Ras signaling; Pancreatic adenocarcinoma pathway; Ciliary landscape; EGF/EGFR signaling pathway"	"6"	"0"	"170.3"	"60.5"	"118.4"	"89.9"	"118.1"	"118.8"	"100.3"	"147.9"	"150.0"	"334.0"	"566.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5T280"	"Putative methyltransferase C9orf114 OS=Homo sapiens OX=9606 GN=SPOUT1 PE=1 SV=3"	"0.000"	""	"6"	"2"	"4"	"2"	"376"	"42.0"	"7.43"	"921.68"	"9.37"	"2"	"2"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02598"	"51490"	"ENSG00000198917"	"SPOUT1"	"hsa:51490; Q0D2P6; Q5T280; Q6P469; Q6PGP9; Q6PIJ1; Q6PJV9"	""	""	"0"	"0"	"75.1"	"36.2"	"73.3"	"64.4"	"74.9"	"86.8"	"57.0"	"76.6"	"86.7"	"552.6"	"865.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25789"	"Proteasome subunit alpha type-4 OS=Homo sapiens OX=9606 GN=PSMA4 PE=1 SV=1"	"0.000"	""	"12"	"3"	"6"	"3"	"261"	"29.5"	"7.72"	"967.02"	"9.36"	"3"	"3"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf00227, Pf10584"	"5685"	"ENSG00000041357"	"PSMA4"	"D3DW86; hsa:5685; P25789; Q53XP2; Q567Q5; Q8TBD1"	"MAPK6/MAPK4 signaling; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Exercise-induced circadian regulation; Alzheimer's disease"	"63"	"0"	"393.6"	"181.2"	"378.2"	"339.9"	"388.8"	"433.9"	"328.0"	"440.5"	"349.4"	"501.6"	"704.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P56545"	"C-terminal-binding protein 2 OS=Homo sapiens OX=9606 GN=CTBP2 PE=1 SV=1"	"0.000"	""	"6"	"3"	"5"	"1"	"445"	"48.9"	"6.95"	"748.33"	"9.34"	"2"	"3"	"cell-cell signaling;cell organization and biogenesis;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00389, Pf02826"	"1488"	"ENSG00000175029"	"CTBP2"	"A8K2X5; D3DRF5; hsa:1488; O43449; P56545; Q5SQP7; Q69YI3; Q86SV0; Q8IY44; Q9H2T8"	"Repression of WNT target genes; Signaling by TCF7L2 mutants"	"Neural crest differentiation; Notch signaling; Mesodermal commitment pathway; Wnt signaling pathway and pluripotency; lncRNA in canonical Wnt signaling and colorectal cancer; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Ciliary landscape; Pleural mesothelioma"	"11"	"2"	"486.7"	"189.9"	"456.7"	"402.0"	"386.6"	"514.5"	"311.1"	"467.5"	"386.4"	"690.4"	"991.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35221"	"Catenin alpha-1 OS=Homo sapiens OX=9606 GN=CTNNA1 PE=1 SV=1"	"0.000"	""	"4"	"2"	"4"	"2"	"906"	"100.0"	"6.29"	"1146.11"	"9.33"	"2"	"2"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01044"	"1495"	"ENSG00000044115"	"CTNNA1"	"hsa:1495; P35221; Q12795; Q8N1C0"	"RHO GTPases activate IQGAPs; Myogenesis; VEGFR2 mediated vascular permeability; Adherens junctions interactions; Regulation of CDH11 function; Regulation of CDH19 Expression and Function; CDH11 homotypic and heterotypic interactions"	"Arrhythmogenic right ventricular cardiomyopathy; Apoptosis-related network due to altered Notch3 in ovarian cancer; VEGFA-VEGFR2 signaling; White fat cell differentiation; Endometrial cancer; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-Merlin signaling dysregulation; Pleural mesothelioma"	"15"	"0"	"55.1"	"16.6"	"39.3"	"33.3"	"40.1"	"40.6"	"38.1"	"59.3"	"48.8"	"73.1"	"143.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00567"	"Nucleolar protein 56 OS=Homo sapiens OX=9606 GN=NOP56 PE=1 SV=4"	"0.000"	""	"6"	"2"	"4"	"2"	"594"	"66.0"	"9.19"	"988.59"	"9.30"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01798, Pf08156"	"10528"	"ENSG00000101361"	"NOP56"	"hsa:10528; O00567; Q2M3T6; Q9NQ05"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol; Association of TriC/CCT with target proteins during biosynthesis"	""	"3"	"0"	"77.6"	"34.5"	"61.4"	"55.7"	"57.6"	"59.8"	"56.8"	"90.6"	"118.4"	"561.5"	"1101.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WXA9"	"Splicing regulatory glutamine/lysine-rich protein 1 OS=Homo sapiens OX=9606 GN=SREK1 PE=1 SV=1"	"0.000"	""	"7"	"2"	"3"	"2"	"508"	"59.3"	"10.39"	"301.07"	"9.29"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf00076"	"140890"	"ENSG00000153914"	"SREK1"	"A4FTW3; hsa:140890; Q2M1J0; Q86X37; Q8WXA9"	""	"mRNA processing"	"1"	"0"	"51.8"	"17.5"	"39.6"	"31.4"	"41.5"	"46.1"	"41.5"	"58.8"	"47.2"	"74.0"	"173.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQ39"	"ATP-dependent RNA helicase DDX50 OS=Homo sapiens OX=9606 GN=DDX50 PE=1 SV=1"	"0.000"	""	"5"	"3"	"6"	"2"	"737"	"82.5"	"9.17"	"1034.51"	"9.29"	"3"	"3"	""	"plasma membrane;other membranes;nucleus"	"other molecular function"	"Pf00270, Pf00271, Pf08152"	"79009"	"ENSG00000107625"	"DDX50"	"hsa:79009; Q5VX37; Q8WV76; Q9BQ39; Q9BWI8"	""	""	"0"	"0"	"215.4"	"63.0"	"126.6"	"98.7"	"135.2"	"135.2"	"96.4"	"130.8"	"105.0"	"193.2"	"399.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75489"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS3 PE=1 SV=1"	"0.000"	""	"20"	"4"	"7"	"4"	"264"	"30.2"	"7.50"	"1823.86"	"9.28"	"4"	"3"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion;nucleus"	"transporter activity;other molecular function"	"Pf00329"	"4722"	"ENSG00000213619; ENSG00000285387"	"NDUFS3"	"B2R9J1; B4DFM8; hsa:4722; O75489; Q9UNQ8"	"RHOG GTPase cycle; Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"6"	"0"	"151.7"	"58.8"	"116.8"	"92.3"	"111.0"	"125.1"	"108.8"	"168.9"	"159.9"	"345.1"	"712.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQA1"	"Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1"	"0.000"	""	"10"	"3"	"6"	"3"	"342"	"36.7"	"5.17"	"891.26"	"9.26"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400"	"79084"	"ENSG00000116455"	"WDR77"	"B3KMW6; B4DP38; hsa:79084; Q3LID2; Q53FU2; Q6JZZ5; Q96GK4; Q9BQA1; Q9BWY3"	"RMTs methylate histone arginines; snRNP Assembly"	""	"2"	"0"	"109.9"	"54.8"	"89.3"	"74.5"	"78.2"	"88.3"	"87.9"	"102.6"	"91.9"	"150.9"	"243.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05386"	"60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1"	"0.000"	""	"19"	"2"	"6"	"2"	"114"	"11.5"	"4.32"	"987.87"	"9.23"	"2"	"2"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00428"	"6176"	"ENSG00000137818"	"RPLP1"	"A6NIB2; hsa:6176; P05386"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"990.2"	"461.5"	"763.3"	"509.7"	"706.7"	"827.2"	"637.0"	"850.6"	"627.5"	"778.8"	"1331.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23381"	"Tryptophan--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=WARS1 PE=1 SV=2"	"0.000"	""	"8"	"2"	"3"	"2"	"471"	"53.1"	"6.23"	"365.73"	"9.22"	"1"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00458, Pf00579"	"7453"	"ENSG00000140105"	"WARS1"	"A6NGN1; A6NID3; hsa:7453; P23381; P78535; Q502Y0; Q53XB6; Q9UDI5; Q9UDL3"	"Cytosolic tRNA aminoacylation"	"Photodynamic therapy-induced unfolded protein response; Amino acid metabolism"	"3"	"0"	"12.6"	"4.7"	"11.7"	"9.6"	"14.6"	"17.4"	"10.8"	"17.3"	"15.2"	"27.8"	"164.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQ52"	"Zinc phosphodiesterase ELAC protein 2 OS=Homo sapiens OX=9606 GN=ELAC2 PE=1 SV=2"	"0.000"	""	"5"	"2"	"3"	"2"	"826"	"92.2"	"7.90"	"480.42"	"9.22"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf12706, Pf13691"	"60528"	"ENSG00000006744"	"ELAC2"	"B4DPL9; hsa:60528; Q6IA94; Q9BQ52; Q9HAS8; Q9HAS9; Q9NVT1"	"tRNA processing in the nucleus; tRNA processing in the mitochondrion; rRNA processing in the mitochondrion; tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis"	""	"4"	"0"	"28.7"	"11.6"	"25.9"	"24.4"	"27.7"	"29.5"	"25.9"	"28.8"	"28.7"	"68.3"	"194.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKS6"	"Protein kinase C and casein kinase substrate in neurons protein 3 OS=Homo sapiens OX=9606 GN=PACSIN3 PE=1 SV=2"	"0.000"	""	"5"	"2"	"5"	"2"	"424"	"48.5"	"6.18"	"663.59"	"9.20"	"1"	"2"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00611, Pf14604"	"29763"	"ENSG00000165912"	"PACSIN3"	"A6NH84; hsa:29763; Q9H331; Q9NWV9; Q9UKS6"	"Clathrin-mediated endocytosis"	""	"1"	"0"	"104.1"	"49.4"	"88.0"	"78.1"	"96.6"	"108.5"	"82.8"	"120.4"	"93.7"	"211.4"	"453.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2D5"	"A-kinase anchor protein 2 OS=Homo sapiens OX=9606 GN=AKAP2 PE=1 SV=3"	"0.000"	""	"3"	"2"	"6"	"2"	"859"	"94.6"	"5.11"	"1075.95"	"9.19"	"2"	"2"	""	""	""	"Pf15304"	"445815"	""	"AKAP2"	"B1ALX9; B2RTU4; B3KQ00; B4DTZ2; B7ZW07; B9EJB5; Q9UG26; Q9Y2D5"	""	""	"0"	"0"	"159.4"	"87.1"	"153.8"	"127.4"	"142.6"	"168.0"	"121.6"	"173.1"	"138.7"	"214.3"	"319.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O76094"	"Signal recognition particle subunit SRP72 OS=Homo sapiens OX=9606 GN=SRP72 PE=1 SV=3"	"0.000"	""	"6"	"3"	"5"	"3"	"671"	"74.6"	"9.26"	"783.70"	"9.15"	"2"	"3"	"transport"	"cytosol;ER/Golgi;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf08492, Pf13181, Pf17004"	"6731"	"ENSG00000174780"	"SRP72"	"G5E9Z8; hsa:6731; O76094; Q7Z3C0"	"SRP-dependent cotranslational protein targeting to membrane"	""	"1"	"0"	"25.4"	"9.0"	"18.7"	"9.2"	"14.7"	"19.2"	"12.5"	"13.8"	"18.8"	"24.2"	"36.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P81605"	"Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2"	"0.000"	""	"25"	"4"	"7"	"4"	"110"	"11.3"	"6.54"	"1238.16"	"9.14"	"4"	"3"	"protein metabolism;stress response;transport;other biological processes"	"non-structural extracellular;other membranes"	"transporter activity;other molecular function"	"Pf15291"	"117159"	"ENSG00000161634"	"DCD"	"A5JHP2; A5JHP3; hsa:117159; P58461; P81605; Q53YJ2"	"Antimicrobial peptides"	""	"1"	"0"	"197.8"	"204.5"	"217.3"	"3345.0"	"265.7"	"84.4"	"211.6"	"270.0"	"181.4"	"334.8"	"540.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5JSZ5"	"Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2"	"0.000"	""	"2"	"3"	"5"	"2"	"2229"	"242.8"	"8.34"	"533.65"	"9.14"	"2"	"3"	"other biological processes"	""	""	"Pf07001"	"84726"	"ENSG00000288701"	"PRRC2B"	"hsa:84726; O60270; Q5JSZ5; Q5JSZ7; Q66VZ2; Q68CR0; Q96EI9; Q9H683"	""	""	"0"	"0"	"66.5"	"34.5"	"46.5"	"36.6"	"41.9"	"47.2"	"40.3"	"56.7"	"49.3"	"68.2"	"89.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60684"	"Importin subunit alpha-7 OS=Homo sapiens OX=9606 GN=KPNA6 PE=1 SV=1"	"0.000"	""	"5"	"3"	"6"	"3"	"536"	"60.0"	"4.98"	"1273.20"	"9.13"	"3"	"2"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf01749, Pf16186"	"23633"	"ENSG00000025800"	"KPNA6"	"B2RDC7; D3DPP5; hsa:23633; O60684; Q5VVU3"	"Assembly of the ORC complex at the origin of replication"	""	"1"	"0"	"429.2"	"233.9"	"457.1"	"468.9"	"456.4"	"601.9"	"407.8"	"471.8"	"348.0"	"624.9"	"1007.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63151"	"Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R2A PE=1 SV=1"	"0.000"	""	"8"	"3"	"6"	"3"	"447"	"51.7"	"6.20"	"1054.50"	"9.07"	"3"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity"	""	"5520"	"ENSG00000221914"	"PPP2R2A"	"B2RBU8; B4E1T7; hsa:5520; P50409; P63151; Q00007"	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Cyclin D associated events in G1; Cyclin A/B1/B2 associated events during G2/M transition; Initiation of Nuclear Envelope (NE) Reformation"	"Wnt signaling pathway and pluripotency; PI3K-Akt signaling pathway; Glycogen synthesis and degradation"	"7"	"0"	"111.1"	"45.4"	"119.2"	"95.0"	"114.6"	"129.1"	"99.9"	"124.2"	"106.3"	"215.0"	"360.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P28288"	"ATP-binding cassette sub-family D member 3 OS=Homo sapiens OX=9606 GN=ABCD3 PE=1 SV=1"	"0.000"	""	"5"	"3"	"5"	"2"	"659"	"75.4"	"9.36"	"712.26"	"9.04"	"2"	"3"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00005, Pf06472"	"5825"	"ENSG00000117528"	"ABCD3"	"D3DT46; hsa:5825; P28288; Q15271; Q6NUN5; Q96DA3; Q9H529"	"RHOA GTPase cycle; RHOC GTPase cycle; Class I peroxisomal membrane protein import; ABC transporters in lipid homeostasis"	"Nuclear receptors in lipid metabolism and toxicity; Fragile X syndrome"	"6"	"0"	"191.0"	"70.5"	"158.4"	"125.3"	"140.7"	"154.6"	"135.5"	"209.4"	"179.9"	"423.0"	"958.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P40429"	"60S ribosomal protein L13a OS=Homo sapiens OX=9606 GN=RPL13A PE=1 SV=2"	"0.000"	""	"17"	"4"	"6"	"4"	"203"	"23.6"	"10.93"	"901.63"	"9.03"	"3"	"3"	"protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00572"	"23521"	"ENSG00000142541"	"RPL13A"	"A8K505; hsa:23521; P40429"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"15"	"0"	"791.0"	"287.1"	"613.5"	"548.0"	"613.9"	"757.1"	"551.6"	"748.2"	"571.5"	"1340.8"	"2208.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62910"	"60S ribosomal protein L32 OS=Homo sapiens OX=9606 GN=RPL32 PE=1 SV=2"	"0.000"	""	"27"	"3"	"6"	"3"	"135"	"15.9"	"11.33"	"970.93"	"9.03"	"3"	"3"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01655"	"6161"	"ENSG00000144713"	"RPL32"	"B2R4Q3; hsa:6161; P02433; P62910"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"211.4"	"93.3"	"169.2"	"162.9"	"168.8"	"189.4"	"159.1"	"222.7"	"189.6"	"364.4"	"520.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14649"	"Myosin light chain 6B OS=Homo sapiens OX=9606 GN=MYL6B PE=1 SV=1"	"0.000"	""	"14"	"2"	"4"	"1"	"208"	"22.8"	"5.73"	"745.84"	"9.00"	"2"	"2"	"other biological processes"	"cytosol;cytoskeleton"	"cytoskeletal activity;other molecular function"	""	"140465"	"ENSG00000196465"	"MYL6B"	"hsa:140465; P14649"	"Smooth Muscle Contraction"	"Ciliary landscape"	"2"	"0"	"5.8"	"0.0"	"5.7"	"4.3"	"5.6"	"4.3"	"6.0"	"8.9"	"5.2"	"31.2"	"66.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14839"	"Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2"	"0.000"	""	"2"	"3"	"6"	"3"	"1912"	"217.9"	"5.86"	"1057.04"	"9.00"	"3"	"3"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf00385, Pf00628, Pf06461, Pf06465, Pf08073, Pf08074"	"1108"	"ENSG00000111642"	"CHD4"	"hsa:1108; Q14839; Q8IXZ5"	"HDACs deacetylate histones; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of PTEN gene transcription; Potential therapeutics for SARS; RNA Polymerase I Transcription Initiation; NGF-stimulated transcription; Regulation of TP53 Activity through Acetylation"	"Rett syndrome causing genes; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"9"	"0"	"256.8"	"80.6"	"205.6"	"177.7"	"214.3"	"277.9"	"254.8"	"355.3"	"279.2"	"371.3"	"653.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99538"	"Legumain OS=Homo sapiens OX=9606 GN=LGMN PE=1 SV=1"	"0.000"	""	"9"	"2"	"3"	"2"	"433"	"49.4"	"6.55"	"323.56"	"8.99"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01650"	"5641"	"ENSG00000100600"	"LGMN"	"hsa:5641; O00123; Q86TV2; Q86TV3; Q99538; Q9BTY1"	"MHC class II antigen presentation; Trafficking and processing of endosomal TLR; Vitamin D (calciferol) metabolism"	"Involvement of d-secretase in neurodegenerative diseases"	"4"	"0"	"24.6"	"15.0"	"24.3"	"24.1"	"19.9"	"27.4"	"24.0"	"33.1"	"35.1"	"142.1"	"283.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99575"	"Ribonucleases P/MRP protein subunit POP1 OS=Homo sapiens OX=9606 GN=POP1 PE=1 SV=2"	"0.000"	""	"3"	"3"	"5"	"3"	"1024"	"114.6"	"9.22"	"698.72"	"8.95"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06978, Pf08170"	"10940"	"ENSG00000104356"	"POP1"	"A8K5W9; hsa:10940; Q15037; Q99575"	"tRNA processing in the nucleus"	""	"1"	"0"	"269.4"	"99.0"	"289.9"	"295.0"	"376.1"	"401.9"	"256.4"	"308.5"	"201.5"	"413.8"	"777.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BVP2"	"Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2"	"0.000"	""	"9"	"3"	"4"	"3"	"549"	"62.0"	"9.16"	"943.18"	"8.94"	"2"	"2"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01926, Pf08701"	"26354"	"ENSG00000163938"	"GNL3"	"B2RDC1; hsa:26354; Q5PU80; Q96SV6; Q96SV7; Q9BVP2; Q9UJY0"	"Major pathway of rRNA processing in the nucleolus and cytosol"	""	"1"	"0"	"43.7"	"13.0"	"29.0"	"25.2"	"32.5"	"29.7"	"30.3"	"32.7"	"33.4"	"48.9"	"103.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q4KMP7"	"TBC1 domain family member 10B OS=Homo sapiens OX=9606 GN=TBC1D10B PE=1 SV=3"	""	""	"3"	"1"	"2"	"1"	"808"	"87.1"	"9.19"	""	"8.94"	""	"1"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol"	"enzyme regulator activity"	"Pf00566"	"26000"	"ENSG00000169221"	"TBC1D10B"	"B9A6L0; hsa:26000; Q4KMP7; Q6IN54; Q6P530; Q71RG7; Q86VC5; Q9H8Z2; Q9NUN6; Q9UFP2"	"TBC/RABGAPs"	""	"1"	"0"	"10.6"	"2.3"	"8.9"	"5.7"	"14.9"	"8.3"	"11.4"	"12.1"	"11.1"	"97.6"	"301.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P41223"	"Protein BUD31 homolog OS=Homo sapiens OX=9606 GN=BUD31 PE=1 SV=2"	"0.000"	""	"19"	"2"	"4"	"2"	"144"	"17.0"	"8.82"	"794.99"	"8.92"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf01125"	"8896"	"ENSG00000106245"	"BUD31"	"A4D274; B7Z4S9; D6W5S6; hsa:8896; P41223; Q6IB53; Q9UDV1"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"159.1"	"43.9"	"88.7"	"70.9"	"84.7"	"95.3"	"67.6"	"137.1"	"137.3"	"499.0"	"788.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NX24"	"H/ACA ribonucleoprotein complex subunit 2 OS=Homo sapiens OX=9606 GN=NHP2 PE=1 SV=1"	"0.000"	""	"33"	"2"	"3"	"2"	"153"	"17.2"	"8.22"	"722.09"	"8.91"	"1"	"2"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf01248"	"55651"	"ENSG00000145912"	"NHP2"	"A6NKY8; hsa:55651; Q9NX24; Q9P095"	"rRNA modification in the nucleus and cytosol; Telomere Extension By Telomerase"	""	"2"	"0"	"50.5"	"24.5"	"51.8"	"45.5"	"55.5"	"62.0"	"43.9"	"66.1"	"72.6"	"421.2"	"607.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35249"	"Replication factor C subunit 4 OS=Homo sapiens OX=9606 GN=RFC4 PE=1 SV=2"	"0.000"	""	"11"	"3"	"6"	"3"	"363"	"39.7"	"8.02"	"829.70"	"8.90"	"3"	"3"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00004, Pf08542"	"5984"	"ENSG00000163918"	"RFC4"	"B4DM41; D3DNV2; hsa:5984; P35249; Q6FHX7"	"Activation of ATR in response to replication stress; Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Polymerase switching on the C-strand of the telomere; Polymerase switching; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER"	"Gastric cancer network 2; Retinoblastoma gene in cancer; DNA replication; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"28"	"0"	"189.4"	"90.4"	"149.4"	"117.0"	"156.1"	"174.6"	"141.2"	"180.9"	"175.0"	"390.5"	"680.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99436"	"Proteasome subunit beta type-7 OS=Homo sapiens OX=9606 GN=PSMB7 PE=1 SV=1"	"0.000"	""	"11"	"3"	"6"	"3"	"277"	"29.9"	"7.68"	"1072.14"	"8.87"	"3"	"3"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00227, Pf12465"	"5695"	"ENSG00000136930"	"PSMB7"	"B4E0P1; hsa:5695; Q5TBG6; Q96AG8; Q99436; Q9BWA7"	"ER-Phagosome pathway; Neutrophil degranulation; Ub-specific processing proteases; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"63"	"0"	"480.5"	"207.9"	"502.7"	"472.9"	"476.8"	"560.9"	"458.2"	"597.1"	"474.1"	"867.2"	"1595.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61254"	"60S ribosomal protein L26 OS=Homo sapiens OX=9606 GN=RPL26 PE=1 SV=1"	"0.000"	""	"17"	"4"	"7"	"4"	"145"	"17.2"	"10.55"	"1237.88"	"8.85"	"4"	"3"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00467, Pf16906"	"6154"	"ENSG00000161970"	"RPL26"	"B2R4F0; D3DTR8; hsa:6154; P61254; Q02877; Q6IPY2"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"15"	"0"	"1078.2"	"394.2"	"903.1"	"843.7"	"852.0"	"1033.7"	"766.7"	"1016.8"	"671.5"	"1299.3"	"1732.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P84090"	"Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1"	"0.001"	""	"34"	"3"	"4"	"3"	"104"	"12.3"	"5.92"	"268.80"	"8.84"	"1"	"3"	"cell cycle OR cell proliferation;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf01133"	"2079"	"ENSG00000100632"	"ERH"	"B2R5H2; hsa:2079; P70659; P84090; Q14259"	""	""	"0"	"0"	"361.8"	"180.1"	"241.5"	"207.2"	"234.6"	"257.0"	"284.8"	"412.4"	"444.1"	"416.0"	"620.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13984"	"General transcription factor IIF subunit 2 OS=Homo sapiens OX=9606 GN=GTF2F2 PE=1 SV=2"	"0.000"	""	"14"	"3"	"6"	"3"	"249"	"28.4"	"9.23"	"981.89"	"8.81"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf02270, Pf17683"	"2963"	"ENSG00000188342"	"GTF2F2"	"A6NNS5; hsa:2963; P13984; Q5W0H3"	"mRNA Splicing - Major Pathway; Viral Messenger RNA Synthesis; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Estrogen-dependent gene expression; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM"	"Eukaryotic transcription initiation"	"33"	"0"	"110.8"	"43.2"	"81.0"	"59.6"	"75.9"	"86.4"	"82.1"	"112.1"	"93.8"	"178.6"	"340.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P28070"	"Proteasome subunit beta type-4 OS=Homo sapiens OX=9606 GN=PSMB4 PE=1 SV=4"	"0.001"	""	"13"	"2"	"3"	"2"	"264"	"29.2"	"5.97"	"284.83"	"8.72"	"1"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00227"	"5692"	"ENSG00000159377"	"PSMB4"	"B2R9L3; hsa:5692; P28070; P31148; Q5SZS5; Q6IBI4; Q969L6"	"Regulation of expression of SLITs and ROBOs; Regulation of PTEN stability and activity; KEAP1-NFE2L2 pathway; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Neddylation; Interleukin-1 signaling; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"62"	"0"	"140.2"	"51.9"	"160.8"	"138.2"	"155.1"	"195.7"	"154.4"	"180.0"	"130.7"	"252.2"	"388.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y520"	"Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4"	"0.000"	""	"1"	"3"	"6"	"2"	"2896"	"316.7"	"9.13"	"853.28"	"8.69"	"3"	"3"	"cell organization and biogenesis;other biological processes"	"cytosol;other cell component"	""	"Pf07001"	"23215"	"ENSG00000117523"	"PRRC2C"	"hsa:23215; Q05DM8; Q49A39; Q6PD54; Q9H2N2; Q9HA05; Q9NSM8; Q9NXL3; Q9UF29; Q9UPQ6; Q9Y520"	""	"VEGFA-VEGFR2 signaling"	"1"	"1"	"253.3"	"137.0"	"222.1"	"222.0"	"260.0"	"287.0"	"239.6"	"261.8"	"209.6"	"510.8"	"841.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BPW8"	"Protein NipSnap homolog 1 OS=Homo sapiens OX=9606 GN=NIPSNAP1 PE=1 SV=1"	"0.000"	""	"14"	"3"	"5"	"3"	"284"	"33.3"	"9.31"	"1386.72"	"8.69"	"3"	"2"	"other biological processes"	"plasma membrane;other membranes;mitochondrion"	"other molecular function"	"Pf07978"	"8508"	"ENSG00000184117"	"NIPSNAP1"	"B2RAY3; hsa:8508; O43800; Q9BPW8"	""	""	"0"	"0"	"110.8"	"46.8"	"103.5"	"101.6"	"110.2"	"152.9"	"116.4"	"144.4"	"114.7"	"236.7"	"461.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99569"	"Plakophilin-4 OS=Homo sapiens OX=9606 GN=PKP4 PE=1 SV=2"	"0.000"	""	"4"	"3"	"6"	"3"	"1192"	"131.8"	"8.94"	"1041.16"	"8.68"	"3"	"3"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00514"	"8502"	"ENSG00000144283"	"PKP4"	"hsa:8502; Q86W91; Q99569"	"Formation of the cornified envelope; RND2 GTPase cycle; RND1 GTPase cycle; RND3 GTPase cycle"	""	"5"	"0"	"12.8"	"3.7"	"7.8"	"6.6"	"6.2"	"8.9"	"5.4"	"13.1"	"8.9"	"20.2"	"36.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3U8"	"60S ribosomal protein L36 OS=Homo sapiens OX=9606 GN=RPL36 PE=1 SV=3"	"0.000"	""	"37"	"5"	"8"	"5"	"105"	"12.2"	"11.59"	"1683.60"	"8.64"	"5"	"3"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus"	"other molecular function"	"Pf01158"	"25873"	"ENSG00000130255"	"RPL36"	"B2R4Y1; D6W634; hsa:25873; Q6FIG1; Q9UQF6; Q9Y3U8"	"Major pathway of rRNA processing in the nucleolus and cytosol; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Selenocysteine synthesis; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"821.0"	"324.6"	"642.6"	"564.6"	"619.2"	"772.7"	"575.0"	"794.1"	"680.2"	"1130.6"	"1520.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75494"	"Serine/arginine-rich splicing factor 10 OS=Homo sapiens OX=9606 GN=SRSF10 PE=1 SV=1"	"0.000"	""	"5"	"2"	"4"	"2"	"262"	"31.3"	"11.27"	"897.14"	"8.63"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"10772"	"ENSG00000188529"	"SRSF10"	"A6NFM6; A6NI42; A6NIU7; B4DJP9; hsa:10772; O60572; O75494; Q5JRH9; Q5JRI0; Q5JRI2; Q5JRI3; Q5JRI4; Q96G09; Q96P17"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"mRNA processing"	"3"	"0"	"750.3"	"165.5"	"368.3"	"291.7"	"379.3"	"396.8"	"343.4"	"451.4"	"401.8"	"803.1"	"1166.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14331"	"Protein FRG1 OS=Homo sapiens OX=9606 GN=FRG1 PE=1 SV=1"	"0.000"	""	"11"	"2"	"4"	"2"	"258"	"29.2"	"9.01"	"948.56"	"8.63"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus"	"cytoskeletal activity"	"Pf06229"	"2483"	"ENSG00000109536; ENSG00000275145; ENSG00000283153; ENSG00000283630"	"FRG1"	"A8K775; hsa:2483; Q14331"	""	""	"0"	"0"	"54.2"	"22.1"	"48.2"	"44.0"	"49.3"	"57.0"	"52.3"	"79.0"	"140.6"	"731.8"	"1080.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y277"	"Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1"	"0.000"	""	"8"	"2"	"5"	"1"	"283"	"30.6"	"8.66"	"620.51"	"8.62"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf01459"	"7419"	"ENSG00000078668"	"VDAC3"	"hsa:7419; Q9UIS0; Q9Y277"	"Ub-specific processing proteases; Mitochondrial calcium ion transport"	"Alzheimer's disease and miRNA effects; Ferroptosis; Hepatitis B infection; Alzheimer's disease"	"6"	"0"	"56.3"	"12.8"	"26.0"	"21.6"	"28.9"	"26.9"	"29.4"	"36.8"	"40.5"	"69.1"	"167.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96HP4"	"Oxidoreductase NAD-binding domain-containing protein 1 OS=Homo sapiens OX=9606 GN=OXNAD1 PE=1 SV=1"	"0.000"	""	"10"	"2"	"3"	"2"	"312"	"34.8"	"8.37"	"496.47"	"8.61"	"1"	"2"	""	""	"other molecular function"	"Pf00175"	"92106"	"ENSG00000154814"	"OXNAD1"	"hsa:92106; Q2HYC7; Q59FA4; Q96HP4"	""	""	"0"	"0"	"18.4"	"7.1"	"14.5"	"12.4"	"14.8"	"18.7"	"18.1"	"23.4"	"33.4"	"211.7"	"517.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13619"	"Cullin-4A OS=Homo sapiens OX=9606 GN=CUL4A PE=1 SV=3"	"0.000"	""	"3"	"2"	"6"	"1"	"759"	"87.6"	"8.13"	"1038.51"	"8.60"	"2"	"2"	"cell cycle OR cell proliferation;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00888, Pf10557"	"8451"	"ENSG00000139842"	"CUL4A"	"A2A2W2; hsa:8451; O75834; Q13619; Q589T6; Q5TC62; Q6UP08; Q9UP17"	"Neddylation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; DNA Damage Recognition in GG-NER; Dual Incision in GG-NER"	"Hippo-Merlin signaling dysregulation; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"13"	"0"	"108.5"	"66.8"	"100.7"	"81.6"	"84.3"	"102.9"	"81.5"	"123.7"	"111.2"	"329.2"	"838.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q53F19"	"Nuclear cap-binding protein subunit 3 OS=Homo sapiens OX=9606 GN=NCBP3 PE=1 SV=2"	"0.000"	""	"5"	"3"	"6"	"3"	"620"	"70.5"	"5.73"	"1075.05"	"8.60"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;stress response;transport"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf10309"	"55421"	"ENSG00000074356"	"NCBP3"	"B3KWG7; hsa:55421; Q53F19; Q7L406; Q96FK1; Q9NXZ4"	""	""	"0"	"0"	"295.5"	"103.9"	"202.9"	"175.0"	"201.5"	"223.3"	"181.2"	"272.8"	"221.4"	"357.9"	"559.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P48047"	"ATP synthase subunit O, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PO PE=1 SV=1"	"0.000"	""	"17"	"3"	"5"	"3"	"213"	"23.3"	"9.96"	"728.45"	"8.57"	"2"	"3"	"other metabolic processes;transport"	"plasma membrane;other membranes;mitochondrion"	"transporter activity"	"Pf00213"	"539"	"ENSG00000241837"	"ATP5PO"	"B2R4E2; hsa:539; P48047; Q5U042; Q6IBI2"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"5"	"0"	"96.3"	"43.5"	"62.3"	"56.1"	"89.7"	"82.0"	"83.3"	"123.3"	"111.7"	"192.2"	"354.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q92576"	"PHD finger protein 3 OS=Homo sapiens OX=9606 GN=PHF3 PE=1 SV=3"	""	""	"1"	"1"	"2"	"1"	"2039"	"229.3"	"6.96"	""	"8.56"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00628, Pf07500, Pf07744"	"23469"	"ENSG00000118482"	"PHF3"	"A3KFI8; hsa:23469; Q14CR5; Q5CZI1; Q5T1T6; Q92576; Q9NQ16; Q9UI45"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75663"	"TIP41-like protein OS=Homo sapiens OX=9606 GN=TIPRL PE=1 SV=2"	"0.000"	""	"18"	"3"	"5"	"3"	"272"	"31.4"	"5.91"	"650.86"	"8.56"	"2"	"3"	"stress response;signal transduction;other biological processes"	"cytosol"	""	"Pf04176"	"261726"	"ENSG00000143155"	"TIPRL"	"B2R8V3; hsa:261726; O75663; Q5HYB2; Q8IZ86"	""	"Ciliary landscape"	"1"	"0"	"236.9"	"125.9"	"274.3"	"242.3"	"243.2"	"305.3"	"201.8"	"279.5"	"184.4"	"317.2"	"572.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13330"	"Metastasis-associated protein MTA1 OS=Homo sapiens OX=9606 GN=MTA1 PE=1 SV=2"	"0.000"	""	"5"	"3"	"5"	"3"	"715"	"80.7"	"9.26"	"724.45"	"8.53"	"2"	"3"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00249, Pf00320, Pf01426, Pf01448, Pf17226"	"9112"	"ENSG00000182979"	"MTA1"	"A5PLK4; hsa:9112; Q13330; Q86SW2; Q8NFI8; Q96GI8"	"HDACs deacetylate histones; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of PTEN gene transcription; Potential therapeutics for SARS; RNA Polymerase I Transcription Initiation; SUMOylation of transcription factors"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; TAR syndrome"	"8"	"0"	"58.9"	"21.7"	"52.2"	"44.0"	"59.6"	"71.4"	"55.1"	"62.9"	"49.7"	"108.7"	"156.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O76003"	"Glutaredoxin-3 OS=Homo sapiens OX=9606 GN=GLRX3 PE=1 SV=2"	"0.000"	""	"10"	"3"	"6"	"3"	"335"	"37.4"	"5.39"	"876.17"	"8.53"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00085, Pf00462"	"10539"	"ENSG00000108010"	"GLRX3"	"B3KMP7; B3KMQ5; D3DRG2; hsa:10539; O76003; Q5JV01; Q96CE0; Q9P1B0; Q9P1B1"	"Iron uptake and transport"	""	"1"	"0"	"217.4"	"91.2"	"247.2"	"190.0"	"214.8"	"270.6"	"158.3"	"190.1"	"155.5"	"253.2"	"438.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y285"	"Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3"	"0.000"	""	"4"	"2"	"6"	"2"	"508"	"57.5"	"7.80"	"1174.50"	"8.52"	"2"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01409, Pf18552, Pf18553, Pf18554"	"2193"	"ENSG00000179115"	"FARSA"	"B4E363; hsa:2193; Q9NSD8; Q9Y285; Q9Y4W8"	"Cytosolic tRNA aminoacylation"	""	"1"	"0"	"305.3"	"144.5"	"280.4"	"251.7"	"261.9"	"294.7"	"201.2"	"285.7"	"255.8"	"453.9"	"672.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14CX7"	"N-alpha-acetyltransferase 25, NatB auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA25 PE=1 SV=1"	"0.000"	""	"3"	"3"	"4"	"3"	"972"	"112.2"	"6.64"	"311.95"	"8.48"	"1"	"3"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;other cell component"	""	"Pf09797"	"80018"	"ENSG00000111300"	"NAA25"	"A0JLU7; hsa:80018; Q14CX7; Q6MZH1; Q7Z4N6; Q9H911"	""	""	"0"	"0"	"53.4"	"28.5"	"40.9"	"35.3"	"40.5"	"42.5"	"38.3"	"59.4"	"33.1"	"213.1"	"905.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14185"	"Dedicator of cytokinesis protein 1 OS=Homo sapiens OX=9606 GN=DOCK1 PE=1 SV=2"	"0.000"	""	"1"	"2"	"5"	"2"	"1865"	"215.2"	"7.56"	"711.50"	"8.45"	"2"	"2"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00018, Pf06920, Pf14429, Pf16172, Pf20421, Pf20422"	"1793"	"ENSG00000150760"	"DOCK1"	"A9Z1Z5; hsa:1793; Q14185"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RAC1 GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; DCC mediated attractive signaling; VEGFA-VEGFR2 Pathway; Factors involved in megakaryocyte development and platelet production; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"	"Integrin-mediated cell adhesion; Androgen receptor network in prostate cancer; Focal adhesion; Hepatocyte growth factor receptor signaling; Regulation of actin cytoskeleton"	"14"	"0"	"92.5"	"43.1"	"82.9"	"62.6"	"70.6"	"99.4"	"150.5"	"326.6"	"368.1"	"1406.7"	"2009.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UJ83"	"2-hydroxyacyl-CoA lyase 1 OS=Homo sapiens OX=9606 GN=HACL1 PE=1 SV=2"	"0.000"	""	"7"	"2"	"3"	"2"	"578"	"63.7"	"7.36"	"543.22"	"8.45"	"1"	"2"	"cell organization and biogenesis;other metabolic processes;transport"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00205, Pf02775, Pf02776"	"26061"	"ENSG00000131373"	"HACL1"	"B4DWI1; B4DXI5; E9PEN4; hsa:26061; Q9BV42; Q9P0A2; Q9UJ83"	"Peroxisomal protein import; Alpha-oxidation of phytanate"	""	"2"	"0"	"52.2"	"21.2"	"51.3"	"50.1"	"53.6"	"63.9"	"42.3"	"60.3"	"40.7"	"158.4"	"463.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P21333"	"Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4"	"0.000"	""	"1"	"2"	"4"	"2"	"2647"	"280.6"	"6.06"	"995.21"	"8.42"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00307, Pf00630"	"2316"	"ENSG00000196924"	"FLNA"	"E9KL45; hsa:2316; P21333; Q5HY53; Q5HY55; Q8NF52"	"OAS antiviral response; Platelet degranulation ; RHO GTPases activate PAKs; GP1b-IX-V activation signalling; Cell-extracellular matrix interactions"	"Androgen receptor signaling pathway; Prolactin signaling pathway; Focal adhesion; Hypothesized pathways in pathogenesis of cardiovascular disease; MAPK signaling pathway; IL-4 signaling pathway; Ebola virus infection in host; Joubert syndrome; NPHP1 deletion syndrome"	"14"	"0"	"43.4"	"12.7"	"34.7"	"31.7"	"30.1"	"43.3"	"29.9"	"40.3"	"29.7"	"52.5"	"90.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19367"	"Hexokinase-1 OS=Homo sapiens OX=9606 GN=HK1 PE=1 SV=3"	"0.000"	""	"5"	"4"	"7"	"4"	"917"	"102.4"	"6.80"	"1570.72"	"8.37"	"4"	"3"	"other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;mitochondrion"	"kinase activity;other molecular function"	"Pf00349, Pf03727"	"3098"	"ENSG00000156515"	"HK1"	"E9PCK0; hsa:3098; O43443; O43444; O75574; P19367; Q5VTC3; Q96HC8; Q9NNZ4; Q9NNZ5"	"Glycolysis; Defective HK1 causes hexokinase deficiency (HK deficiency)"	"Cori cycle; Photodynamic therapy-induced HIF-1 survival signaling; Clear cell renal cell carcinoma pathways; Aerobic glycolysis; Disorders of fructose metabolism; Glucose metabolism in triple-negative breast cancer cells; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders; UDP-derived sugars synthesis in fibroblasts; Glucuronidation"	"12"	"0"	"285.0"	"142.0"	"248.2"	"227.1"	"226.0"	"297.4"	"208.8"	"255.2"	"218.1"	"300.0"	"702.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35241"	"Radixin OS=Homo sapiens OX=9606 GN=RDX PE=1 SV=1"	"0.000"	""	"5"	"3"	"4"	"1"	"583"	"68.5"	"6.37"	"298.86"	"8.35"	"1"	"3"	"cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf00769, Pf09379, Pf09380, Pf20492"	"5962"	"ENSG00000137710"	"RDX"	"A7YIJ8; A7YIK0; A7YIK3; B7Z9U6; F5H1A7; hsa:5962; P35241; Q86Y61"	"Recycling pathway of L1; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea"	"Regulation of actin cytoskeleton"	"4"	"0"	"42.6"	"11.8"	"35.3"	"19.4"	"29.7"	"33.6"	"31.1"	"33.0"	"25.6"	"100.9"	"319.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15294"	"UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3"	"0.000"	""	"4"	"4"	"6"	"4"	"1046"	"116.9"	"6.70"	"874.24"	"8.31"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00515, Pf13181, Pf13414, Pf13424, Pf13844"	"8473"	"ENSG00000147162"	"OGT"	"hsa:8473; O15294; Q7Z3K0; Q8WWM8; Q96CC1; Q9UG57"	"UCH proteinases; Formation of WDR5-containing histone-modifying complexes; Regulation of necroptotic cell death; HATs acetylate histones"	"Ectoderm differentiation; Ectoderm differentiation; Pleural mesothelioma"	"8"	"0"	"333.6"	"148.4"	"316.9"	"260.9"	"263.2"	"326.1"	"229.3"	"297.3"	"206.8"	"339.0"	"675.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBS4"	"DnaJ homolog subfamily B member 11 OS=Homo sapiens OX=9606 GN=DNAJB11 PE=1 SV=1"	"0.000"	""	"12"	"3"	"4"	"3"	"358"	"40.5"	"6.18"	"938.78"	"8.30"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00226, Pf01556"	"51726"	"ENSG00000090520"	"DNAJB11"	"hsa:51726; Q542Y5; Q542Y9; Q6IAQ8; Q96JC6; Q9UBS4"	"XBP1(S) activates chaperone genes"	"Photodynamic therapy-induced unfolded protein response"	"2"	"0"	"236.9"	"108.1"	"265.8"	"223.4"	"285.7"	"314.4"	"200.5"	"263.6"	"167.5"	"432.1"	"742.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EY5"	"Multivesicular body subunit 12A OS=Homo sapiens OX=9606 GN=MVB12A PE=1 SV=1"	"0.000"	""	"11"	"2"	"4"	"2"	"273"	"28.8"	"8.91"	"734.38"	"8.28"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf10240"	"93343"	"ENSG00000141971"	"MVB12A"	"hsa:93343; Q96EY5; Q96I18"	"Budding and maturation of HIV virion; Membrane binding and targetting of GAG proteins; Endosomal Sorting Complex Required For Transport (ESCRT); Late endosomal microautophagy; HCMV Late Events"	"7q11.23 copy number variation syndrome"	"6"	"0"	"64.4"	"27.2"	"58.1"	"48.3"	"59.3"	"72.1"	"64.0"	"109.3"	"125.6"	"311.9"	"600.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13363"	"C-terminal-binding protein 1 OS=Homo sapiens OX=9606 GN=CTBP1 PE=1 SV=2"	"0.000"	""	"6"	"3"	"5"	"1"	"440"	"47.5"	"6.77"	"683.89"	"8.28"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00389, Pf02826"	"1487"	"ENSG00000159692"	"CTBP1"	"hsa:1487; Q13363; Q4W5N3; Q7Z2Q5"	"SUMOylation of transcription cofactors; Deactivation of the beta-catenin transactivating complex; Repression of WNT target genes; Signaling by TCF7L2 mutants"	"Notch signaling; Ectoderm differentiation; Ectoderm differentiation; Wnt signaling pathway; Pathways affected in adenoid cystic carcinoma; Wnt signaling pathway and pluripotency; lncRNA in canonical Wnt signaling and colorectal cancer; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Pleural mesothelioma"	"14"	"0"	"16.8"	"8.9"	"16.4"	"10.4"	"15.7"	"16.0"	"12.2"	"13.4"	"13.9"	"32.7"	"68.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P36776"	"Lon protease homolog, mitochondrial OS=Homo sapiens OX=9606 GN=LONP1 PE=1 SV=2"	"0.000"	""	"4"	"3"	"6"	"3"	"959"	"106.4"	"6.39"	"996.44"	"8.26"	"3"	"3"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00004, Pf02190, Pf05362"	"9361"	"ENSG00000196365"	"LONP1"	"B3KPH8; D6W635; E5KMH8; F5GZ27; hsa:9361; P36776; P36777; Q8N8K8; Q9UQ95"	""	""	"0"	"0"	"70.7"	"29.3"	"68.9"	"49.6"	"74.1"	"71.3"	"59.2"	"79.7"	"56.1"	"146.8"	"304.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P48729"	"Casein kinase I isoform alpha OS=Homo sapiens OX=9606 GN=CSNK1A1 PE=1 SV=2"	"0.001"	""	"9"	"2"	"3"	"2"	"337"	"38.9"	"9.57"	"265.13"	"8.24"	"1"	"2"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1452"	"ENSG00000113712"	"CSNK1A1"	"D3DQG0; D3DQG1; hsa:1452; P48729; Q4JJA0; Q5U046; Q5U047; Q6FGA2; Q71TU5; Q96HD2; Q9UDK3"	"Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Disassembly of the destruction complex and recruitment of AXIN to the membrane; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; Activation of SMO; APC truncation mutants have impaired AXIN binding; AXIN missense mutants destabilize the destruction complex; Truncations of AMER1 destabilize the destruction complex; Maturation of nucleoprotein"	"Alzheimer's disease and miRNA effects; T cell receptor and co-stimulatory signaling; Complement system; Wnt signaling pathway; Wnt/beta-catenin signaling pathway in leukemia; Regulation of Wnt / B-catenin signaling by small molecule compounds; Chromosomal and microsatellite instability in colorectal cancer ; Hedgehog signaling pathway; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Influence of laminopathies on Wnt signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies; Pleural mesothelioma; Alzheimer's disease; DYRK1A involvement regarding cell proliferation in brain development"	"32"	"0"	"22.9"	"9.0"	"23.7"	"15.8"	"18.4"	"22.7"	"16.9"	"16.8"	"15.3"	"58.2"	"66.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35269"	"General transcription factor IIF subunit 1 OS=Homo sapiens OX=9606 GN=GTF2F1 PE=1 SV=2"	"0.000"	""	"9"	"3"	"6"	"3"	"517"	"58.2"	"7.49"	"746.35"	"8.23"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf05793"	"2962"	"ENSG00000125651"	"GTF2F1"	"B2RCS0; hsa:2962; P35269; Q9BWN0"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; Viral Messenger RNA Synthesis; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Estrogen-dependent gene expression; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM"	""	"32"	"0"	"66.8"	"34.7"	"69.0"	"54.6"	"66.7"	"74.9"	"63.6"	"81.2"	"88.3"	"187.6"	"186.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13667"	"Protein disulfide-isomerase A4 OS=Homo sapiens OX=9606 GN=PDIA4 PE=1 SV=2"	"0.000"	""	"9"	"5"	"8"	"4"	"645"	"72.9"	"5.07"	"1575.57"	"8.22"	"4"	"3"	"protein metabolism;other metabolic processes;stress response;transport"	"non-structural extracellular;ER/Golgi;other cell component"	"other molecular function"	"Pf00085, Pf13848"	"9601"	"ENSG00000155660"	"PDIA4"	"A8K4K6; hsa:9601; P13667; Q549T6"	""	""	"0"	"1"	"1020.5"	"467.6"	"803.7"	"698.1"	"893.4"	"983.0"	"743.3"	"985.4"	"790.3"	"1341.2"	"1871.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15355"	"Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1"	"0.000"	""	"3"	"2"	"6"	"2"	"546"	"59.2"	"4.36"	"960.50"	"8.22"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf00481"	"5496"	"ENSG00000115241"	"PPM1G"	"hsa:5496; O15355"	""	"VEGFA-VEGFR2 signaling; mRNA processing"	"2"	"0"	"337.0"	"168.4"	"319.7"	"239.8"	"291.0"	"367.7"	"300.0"	"363.3"	"322.0"	"472.9"	"798.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P12694"	"2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=BCKDHA PE=1 SV=2"	"0.000"	""	"7"	"2"	"4"	"2"	"445"	"50.4"	"8.27"	"645.44"	"8.21"	"2"	"2"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00676"	"593"	"ENSG00000248098"	"BCKDHA"	"B4DP47; E7EW46; hsa:593; P12694; Q16034; Q16472"	"Glyoxylate metabolism and glycine degradation; Branched-chain amino acid catabolism"	"Lipid metabolism pathway"	"3"	"0"	"40.1"	"22.4"	"32.8"	"28.5"	"34.2"	"44.1"	"36.5"	"47.9"	"46.2"	"103.8"	"205.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75955"	"Flotillin-1 OS=Homo sapiens OX=9606 GN=FLOT1 PE=1 SV=3"	"0.000"	""	"4"	"1"	"4"	"1"	"427"	"47.3"	"7.49"	"965.16"	"8.21"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01145"	"10211"	"ENSG00000137312; ENSG00000206379; ENSG00000206480; ENSG00000230143; ENSG00000232280"	"FLOT1"	"B4DVY7; hsa:10211; O75955; Q969J8; Q9UHW1; Q9UNV8"	"RHOC GTPase cycle; RHOA GTPase cycle; RHOB GTPase cycle; Regulation of necroptotic cell death; Synaptic adhesion-like molecules"	"Angiopoietin-like protein 8 regulatory pathway; Insulin signaling"	"8"	"0"	"64.9"	"17.9"	"29.3"	"19.4"	"29.3"	"28.1"	"26.6"	"33.2"	"37.4"	"50.6"	"133.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UHR5"	"SAP30-binding protein OS=Homo sapiens OX=9606 GN=SAP30BP PE=1 SV=1"	"0.000"	""	"8"	"2"	"4"	"2"	"308"	"33.9"	"4.84"	"912.23"	"8.20"	"2"	"2"	"other biological processes"	"cytoskeleton;nucleus"	""	"Pf07818"	"29115"	"ENSG00000161526"	"SAP30BP"	"B3KML7; hsa:29115; Q8N1R5; Q8TDR8; Q96D27; Q9UHR5"	"NoRC negatively regulates rRNA expression"	""	"1"	"0"	"77.5"	"31.3"	"74.2"	"53.1"	"71.6"	"82.4"	"57.0"	"87.7"	"62.8"	"94.1"	"187.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBU8"	"Mortality factor 4-like protein 1 OS=Homo sapiens OX=9606 GN=MORF4L1 PE=1 SV=2"	"0.000"	""	"6"	"2"	"4"	"2"	"362"	"41.4"	"9.28"	"848.13"	"8.19"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf05712, Pf11717"	"10933"	"ENSG00000185787"	"MORF4L1"	"B4DKN6; B7Z6R1; D3DW88; hsa:10933; O95899; Q5QTS1; Q6NVX8; Q86YT7; Q9HBP6; Q9NSW5; Q9UBU8"	"HATs acetylate histones"	"Pathways affected in adenoid cystic carcinoma"	"2"	"0"	"175.4"	"98.7"	"181.8"	"147.5"	"141.1"	"200.5"	"128.9"	"193.2"	"131.8"	"399.0"	"788.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P60953"	"Cell division control protein 42 homolog OS=Homo sapiens OX=9606 GN=CDC42 PE=1 SV=2"	"0.000"	""	"6"	"1"	"4"	"1"	"191"	"21.2"	"6.55"	"894.80"	"8.18"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00071"	"998"	"ENSG00000070831"	"CDC42"	"hsa:998; P21181; P25763; P60953; Q7L8R5; Q9UDI2"	"RHO GTPases activate IQGAPs; RAC1 GTPase cycle; RHOG GTPase cycle; MAPK6/MAPK4 signaling; EGFR downregulation; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; RHO GTPases Activate Formins; EPHB-mediated forward signaling; VEGFA-VEGFR2 Pathway; Factors involved in megakaryocyte development and platelet production; CDC42 GTPase cycle; RHOQ GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOJ GTPase cycle; RHOV GTPase cycle; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; RHOU GTPase cycle; DCC mediated attractive signaling; GPVI-mediated activation cascade; Myogenesis; G beta:gamma signalling through CDC42; RHO GTPases activate PAKs; Inactivation of CDC42 and RAC1; CD28 dependent Vav1 pathway; RHO GTPases activate KTN1"	"Androgen receptor signaling pathway; Target of rapamycin signaling; Integrin-mediated cell adhesion; RANKL/RANK signaling pathway; Leptin signaling pathway; Microtubule cytoskeleton regulation; Metastatic brain tumor; Pathogenic Escherichia coli infection; RalA downstream regulated genes; B cell receptor signaling pathway; AGE/RAGE pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Spinal cord injury; Focal adhesion; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Oxidative damage response; p38 MAPK signaling pathway; Ebola virus infection in host; Ras signaling; Pancreatic adenocarcinoma pathway; EGF/EGFR signaling pathway; Nonalcoholic fatty liver disease; Hippo signaling regulation pathways; 22q11.2 copy number variation syndrome; Gastrin signaling pathway; Regulation of actin cytoskeleton; G13 signaling pathway; Genetic causes of porto-sinusoidal vascular disease; 13q12.12 copy number variation; T-cell receptor signaling pathway; DNA damage response (only ATM dependent)"	"61"	"0"	"218.8"	"70.2"	"195.7"	"172.9"	"191.8"	"200.0"	"177.4"	"218.8"	"185.1"	"503.2"	"1192.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H223"	"EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1"	""	""	"6"	"3"	"3"	"3"	"541"	"61.1"	"6.76"	""	"8.09"	""	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00350, Pf12763, Pf16880, Pf18150"	"30844"	"ENSG00000103966"	"EHD4"	"hsa:30844; Q9H223; Q9HAR1; Q9NZN2"	""	""	"0"	"0"	"17.5"	"9.1"	"15.2"	"25.6"	"21.2"	"18.4"	"11.6"	"23.0"	"13.9"	"64.6"	"314.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07196"	"Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3"	"0.000"	""	"9"	"4"	"8"	"3"	"543"	"61.5"	"4.65"	"2099.38"	"8.07"	"4"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00038, Pf04732"	"4747"	"ENSG00000277586"	"NEFL"	"B9ZVN2; hsa:4747; P07196; Q16154; Q8IU72"	"Assembly and cell surface presentation of NMDA receptors; RAF/MAP kinase cascade; Ras activation upon Ca2+ influx through NMDA receptor; Unblocking of NMDA receptors, glutamate binding and activation; Negative regulation of NMDA receptor-mediated neuronal transmission; Long-term potentiation"	"Amyotrophic lateral sclerosis (ALS); Physico-chemical features and toxicity-associated pathways; NO/cGMP/PKG mediated neuroprotection; Ciliary landscape; Intracellular trafficking proteins involved in CMT neuropathy; CCL18 signaling pathway"	"12"	"0"	"495.8"	"118.4"	"335.3"	"290.5"	"373.5"	"384.1"	"273.6"	"377.3"	"234.5"	"485.6"	"986.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBW8"	"COP9 signalosome complex subunit 7a OS=Homo sapiens OX=9606 GN=COPS7A PE=1 SV=1"	"0.000"	""	"8"	"2"	"3"	"2"	"275"	"30.3"	"8.22"	"307.16"	"8.01"	"1"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf01399, Pf18392"	"50813"	"ENSG00000111652"	"COPS7A"	"A8K9A6; hsa:50813; Q9NVX3; Q9UBW8; Q9UJW4"	"Cargo recognition for clathrin-mediated endocytosis; Formation of TC-NER Pre-Incision Complex; Neddylation; DNA Damage Recognition in GG-NER"	"Ciliary landscape"	"5"	"0"	"134.2"	"81.1"	"108.8"	"74.6"	"93.3"	"149.4"	"170.6"	"279.4"	"286.8"	"543.7"	"1504.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14689"	"Disco-interacting protein 2 homolog A OS=Homo sapiens OX=9606 GN=DIP2A PE=1 SV=2"	"0.001"	""	"2"	"3"	"4"	"1"	"1571"	"170.3"	"8.03"	"260.73"	"8.01"	"1"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf00501, Pf06464"	"23181"	"ENSG00000160305"	"DIP2A"	"A6P4T3; B4E0F0; E7EMA5; hsa:23181; Q14689; Q8IVA3; Q8N4S2; Q8TD89; Q96ML9"	""	"Mesodermal commitment pathway"	"1"	"0"	"101.2"	"46.0"	"74.3"	"63.7"	"76.9"	"91.8"	"90.1"	"155.9"	"174.3"	"492.8"	"663.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BUL8"	"Programmed cell death protein 10 OS=Homo sapiens OX=9606 GN=PDCD10 PE=1 SV=1"	"0.000"	""	"15"	"3"	"6"	"3"	"212"	"24.7"	"8.19"	"973.46"	"8.01"	"3"	"3"	"cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf06840"	"11235"	"ENSG00000114209"	"PDCD10"	"A8K515; D3DNN5; hsa:11235; O14811; Q9BUL8"	""	""	"0"	"0"	"352.6"	"142.4"	"287.7"	"228.0"	"275.0"	"335.1"	"250.6"	"321.7"	"277.3"	"468.9"	"653.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96SB3"	"Neurabin-2 OS=Homo sapiens OX=9606 GN=PPP1R9B PE=1 SV=3"	"0.000"	""	"2"	"2"	"5"	"1"	"817"	"89.3"	"4.97"	"699.71"	"8.00"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;kinase activity;other molecular function"	"Pf00595, Pf17817"	"84687"	"ENSG00000108819"	"PPP1R9B"	"D3DTX6; hsa:84687; Q8TCR9; Q96SB3"	""	""	"0"	"0"	"72.1"	"34.2"	"68.8"	"57.4"	"74.2"	"87.7"	"57.7"	"74.8"	"60.1"	"104.0"	"195.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94826"	"Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1"	"0.000"	""	"3"	"2"	"4"	"2"	"608"	"67.4"	"7.12"	"835.72"	"7.98"	"2"	"2"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00515, Pf13181"	"9868"	"ENSG00000154174"	"TOMM70"	"D3DN48; hsa:9868; O94826"	"Ub-specific processing proteases; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Mitochondrial protein import; DDX58/IFIH1-mediated induction of interferon-alpha/beta; SARS-CoV-1 activates/modulates innate immune responses; PINK1-PRKN Mediated Mitophagy"	"Mitochondrial immune response to SARS-CoV-2; SARS-CoV-2 B.1.1.7 variant antagonises innate immune activation; SARS-CoV-2 mitochondrial chronic oxidative stress and endothelial dysfunction"	"9"	"0"	"228.3"	"96.7"	"216.9"	"174.7"	"183.7"	"220.5"	"157.9"	"199.2"	"154.6"	"580.8"	"1713.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61024"	"Cyclin-dependent kinases regulatory subunit 1 OS=Homo sapiens OX=9606 GN=CKS1B PE=1 SV=1"	"0.000"	""	"20"	"2"	"4"	"2"	"79"	"9.7"	"8.94"	"698.35"	"7.97"	"2"	"2"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01111"	"1163"	"ENSG00000173207"	"CKS1B"	"hsa:1163; P33551; P61024"	"SCF(Skp2)-mediated degradation of p27/p21; Cyclin D associated events in G1"	"Small cell lung cancer"	"3"	"0"	"346.3"	"156.4"	"337.2"	"293.2"	"322.5"	"402.0"	"297.9"	"414.6"	"331.0"	"610.4"	"1280.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5T8P6"	"RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3"	"0.000"	""	"2"	"2"	"4"	"2"	"1007"	"113.5"	"9.16"	"901.22"	"7.97"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf01480"	"64062"	"ENSG00000139746"	"RBM26"	"B4DZE0; hsa:64062; Q2NKM2; Q2NKQ2; Q5CZH8; Q5T8P5; Q5T8P6; Q5T8P8; Q5U5P5; Q5W0G7; Q8N3H5; Q96K92; Q96SZ3; Q9H2F8; Q9H7F9; Q9P1G7"	""	""	"0"	"0"	"189.3"	"70.7"	"115.0"	"91.3"	"124.8"	"145.1"	"114.0"	"181.8"	"138.3"	"211.3"	"405.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43920"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 OS=Homo sapiens OX=9606 GN=NDUFS5 PE=1 SV=3"	"0.000"	""	"22"	"2"	"4"	"2"	"106"	"12.5"	"9.14"	"698.73"	"7.96"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf10200"	"4725"	"ENSG00000168653"	"NDUFS5"	"hsa:4725; O43920"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"5"	"0"	"226.6"	"160.5"	"265.8"	"216.0"	"263.5"	"294.8"	"218.4"	"282.7"	"229.7"	"371.6"	"538.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00291"	"Huntingtin-interacting protein 1 OS=Homo sapiens OX=9606 GN=HIP1 PE=1 SV=5"	"0.000"	""	"2"	"2"	"4"	"2"	"1037"	"116.1"	"5.30"	"778.79"	"7.96"	"2"	"2"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf01608, Pf07651, Pf16515"	"3092"	"ENSG00000127946"	"HIP1"	"B4E3I7; E7ES17; hsa:3092; O00291; O00328; Q2TB58; Q8TDL4; V5LU97"	"Clathrin-mediated endocytosis; ALK mutants bind TKIs; Signaling by ALK fusions and activated point mutants"	"DYRK1A involvement regarding cell proliferation in brain development; 5q35 copy number variation"	"5"	"0"	"33.2"	"11.3"	"31.6"	"22.2"	"34.8"	"27.6"	"19.4"	"34.4"	"27.9"	"72.8"	"294.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q08J23"	"RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2"	"0.000"	""	"6"	"2"	"3"	"2"	"767"	"86.4"	"6.77"	"481.25"	"7.94"	"1"	"2"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytoskeleton;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01189"	"54888"	"ENSG00000037474"	"NSUN2"	"A8K529; B2RNR4; B3KP09; B4DQW2; G3V1R4; hsa:54888; Q08J23; Q9BVN4; Q9H858; Q9NXD9"	"tRNA modification in the nucleus and cytosol"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UPQ3"	"Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=AGAP1 PE=1 SV=4"	"0.000"	""	"5"	"3"	"4"	"2"	"857"	"94.4"	"7.94"	"492.54"	"7.93"	"2"	"2"	"transport;other biological processes"	"other cell component"	"enzyme regulator activity;other molecular function"	"Pf00071, Pf01412, Pf12796"	"116987"	"ENSG00000157985"	"AGAP1"	"B2RTX7; hsa:116987; Q541S5; Q6P9D7; Q9NV93; Q9UPQ3"	""	"2q37 copy number variation syndrome"	"1"	"0"	"38.5"	"22.0"	"36.3"	"35.5"	"43.1"	"43.9"	"40.4"	"56.0"	"54.0"	"146.3"	"225.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3E1"	"Hepatoma-derived growth factor-related protein 3 OS=Homo sapiens OX=9606 GN=HDGFL3 PE=1 SV=1"	"0.000"	""	"8"	"1"	"4"	"1"	"203"	"22.6"	"7.99"	"834.04"	"7.92"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus"	"signal transduction activity or receptor binding;cytoskeletal activity"	"Pf00855"	"50810"	"ENSG00000166503"	"HDGFL3"	"hsa:50810; Q9Y3E1"	""	""	"0"	"0"	"28.0"	"16.4"	"25.2"	"19.7"	"22.6"	"28.8"	"37.0"	"62.4"	"58.9"	"97.4"	"130.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94905"	"Erlin-2 OS=Homo sapiens OX=9606 GN=ERLIN2 PE=1 SV=1"	"0.000"	""	"7"	"3"	"5"	"3"	"339"	"37.8"	"5.62"	"626.80"	"7.91"	"2"	"3"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf01145"	"11160"	"ENSG00000147475"	"ERLIN2"	"A0JLQ1; A8K5S9; B4DM38; D3DSW0; hsa:11160; O94905; Q6NW21; Q86VS6; Q86W49"	"ABC-family proteins mediated transport; Defective CFTR causes cystic fibrosis; Signaling by FGFR1 in disease; Signaling by plasma membrane FGFR1 fusions"	""	"4"	"0"	"716.9"	"207.8"	"408.1"	"368.9"	"461.7"	"484.7"	"359.4"	"558.0"	"463.4"	"894.5"	"1847.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WUD4"	"Coiled-coil domain-containing protein 12 OS=Homo sapiens OX=9606 GN=CCDC12 PE=1 SV=1"	"0.001"	""	"18"	"2"	"3"	"2"	"166"	"19.2"	"7.34"	"244.67"	"7.87"	"1"	"2"	""	"nucleus"	""	"Pf08315"	"151903"	"ENSG00000160799"	"CCDC12"	"hsa:151903; Q8N8I4; Q8WUD4"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"251.9"	"94.4"	"140.0"	"121.0"	"157.3"	"175.8"	"136.7"	"209.1"	"188.7"	"330.1"	"631.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00232"	"26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3"	"0.000"	""	"7"	"3"	"6"	"3"	"456"	"52.9"	"7.65"	"829.38"	"7.80"	"3"	"3"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf01399, Pf18098"	"5718"	"ENSG00000197170"	"PSMD12"	"A6NP15; hsa:5718; O00232; Q53HA2; Q6P053"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"65"	"0"	"123.7"	"49.4"	"105.0"	"101.7"	"104.8"	"128.8"	"87.7"	"106.7"	"84.8"	"171.3"	"333.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O75940"	"Survival of motor neuron-related-splicing factor 30 OS=Homo sapiens OX=9606 GN=SMNDC1 PE=1 SV=1"	""	""	"13"	"2"	"2"	"2"	"238"	"26.7"	"7.24"	""	"7.78"	""	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf06003"	"10285"	"ENSG00000119953"	"SMNDC1"	"B2RA27; D3DRB1; hsa:10285; O75940; Q5T3K6"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"99.3"	"32.2"	"81.7"	"55.3"	"64.1"	"70.5"	"53.6"	"79.4"	"99.8"	"270.3"	"802.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23258"	"Tubulin gamma-1 chain OS=Homo sapiens OX=9606 GN=TUBG1 PE=1 SV=2"	"0.000"	""	"4"	"3"	"7"	"3"	"451"	"51.1"	"6.14"	"1307.41"	"7.77"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00091, Pf03953"	"7283"	"ENSG00000131462"	"TUBG1"	"hsa:7283; P23258; Q53X79; Q9BW59"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"Alstrom syndrome"	"8"	"0"	"195.2"	"83.2"	"150.2"	"113.3"	"150.1"	"155.9"	"129.4"	"182.1"	"206.4"	"1295.3"	"2462.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NP97"	"Dynein light chain roadblock-type 1 OS=Homo sapiens OX=9606 GN=DYNLRB1 PE=1 SV=3"	"0.000"	""	"29"	"2"	"4"	"2"	"96"	"10.9"	"7.25"	"1027.13"	"7.76"	"2"	"2"	"other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03259"	"83658"	"ENSG00000125971"	"DYNLRB1"	"B1AKR5; hsa:83658; Q5TC72; Q96IV3; Q9NP97; Q9NQM2"	"Intraflagellar transport"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; 3q29 copy number variation syndrome"	"4"	"0"	"238.8"	"125.4"	"245.2"	"175.4"	"234.7"	"285.0"	"211.1"	"241.0"	"229.1"	"332.7"	"492.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P41250"	"Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3"	"0.000"	""	"3"	"2"	"6"	"1"	"739"	"83.1"	"7.03"	"841.35"	"7.74"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"non-structural extracellular;cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00458, Pf00587, Pf03129"	"2617"	"ENSG00000106105"	"GARS1"	"A0A090N8G0; B3KQA2; B4DIA0; hsa:2617; P41250; Q969Y1"	"Cytosolic tRNA aminoacylation; Mitochondrial tRNA aminoacylation"	""	"2"	"0"	"25.0"	"8.0"	"18.3"	"11.9"	"24.0"	"12.9"	"14.6"	"19.3"	"20.2"	"32.4"	"63.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BTC0"	"Death-inducer obliterator 1 OS=Homo sapiens OX=9606 GN=DIDO1 PE=1 SV=5"	"0.000"	""	"1"	"2"	"4"	"2"	"2240"	"243.7"	"7.88"	"720.38"	"7.73"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;signal transduction"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00628, Pf07500, Pf07744"	"11083"	"ENSG00000101191"	"DIDO1"	"A8MY65; B9EH82; E1P5I1; hsa:11083; O15043; Q3ZTL7; Q3ZTL8; Q4VXS1; Q4VXS2; Q4VXV8; Q4VXV9; Q96D72; Q9BQW0; Q9BTC0; Q9BW03; Q9H4G6; Q9H4G7; Q9NTU8; Q9NUM8; Q9UFB6"	""	""	"0"	"0"	"22.9"	"12.8"	"17.6"	"12.8"	"20.6"	"25.2"	"21.7"	"19.9"	"25.1"	"36.9"	"39.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P10155"	"60 kDa SS-A/Ro ribonucleoprotein OS=Homo sapiens OX=9606 GN=RO60 PE=1 SV=2"	"0.000"	""	"7"	"3"	"5"	"3"	"538"	"60.6"	"8.03"	"1136.96"	"7.72"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05731"	"6738"	"ENSG00000116747"	"RO60"	"B2RBB9; hsa:6738; P10155; Q5LJ98; Q5LJ99; Q5LJA0; Q86WL3; Q86WL4; Q92787; Q9H1W6"	""	""	"0"	"0"	"89.1"	"42.2"	"85.5"	"96.1"	"89.1"	"119.6"	"105.6"	"124.8"	"101.3"	"162.1"	"288.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2E4"	"Disco-interacting protein 2 homolog C OS=Homo sapiens OX=9606 GN=DIP2C PE=1 SV=2"	"0.000"	""	"3"	"3"	"4"	"2"	"1556"	"170.7"	"7.39"	"376.45"	"7.71"	"1"	"3"	""	""	""	"Pf00501, Pf06464"	"22982"	"ENSG00000151240"	"DIP2C"	"B4DPI5; hsa:22982; Q5SS78; Q9Y2E4"	""	""	"0"	"0"	"10.2"	"3.6"	"9.7"	"6.1"	"8.4"	"9.8"	"10.5"	"17.0"	"12.9"	"25.6"	"34.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13547"	"Histone deacetylase 1 OS=Homo sapiens OX=9606 GN=HDAC1 PE=1 SV=1"	"0.000"	""	"7"	"3"	"5"	"3"	"482"	"55.1"	"5.48"	"1153.45"	"7.65"	"3"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00850"	"3065"	"ENSG00000116478"	"HDAC1"	"hsa:3065; Q13547; Q92534"	"Potential therapeutics for SARS; Estrogen-dependent gene expression; Formation of the beta-catenin:TCF transactivating complex; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; SUMOylation of chromatin organization proteins; Regulation of PTEN gene transcription; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes; SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Deactivation of the beta-catenin transactivating complex; MECP2 regulates transcription of neuronal ligands; Factors involved in megakaryocyte development and platelet production; Downregulation of SMAD2/3:SMAD4 transcriptional activity; RNA Polymerase I Transcription Initiation; p75NTR negatively regulates cell cycle via SC1; NOTCH1 Intracellular Domain Regulates Transcription; Notch-HLH transcription pathway; Regulation of MECP2 expression and activity; STAT3 nuclear events downstream of ALK signaling; G1/S-Specific Transcription; Regulation of TP53 Activity through Acetylation; Transcription of E2F targets under negative control by DREAM complex; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1; MECP2 regulates neuronal receptors and channels; Repression of WNT target genes; Loss of MECP2 binding ability to 5mC-DNA"	"Androgen receptor signaling pathway; Energy metabolism; Cell cycle; TNF-related weak inducer of apoptosis (TWEAK) signaling pathway; Neural crest differentiation; Retinoblastoma gene in cancer; Notch signaling; Apoptosis-related network due to altered Notch3 in ovarian cancer; Initiation of transcription and translation elongation at the HIV-1 LTR; MECP2 and associated Rett syndrome; IL6 signaling pathway; Valproic acid pathway; VEGFA-VEGFR2 signaling; Ethanol effects on histone modifications; Rett syndrome causing genes; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; Ciliary landscape; Transcription co-factors SKI and SKIL protein partners; Overlap between signal transduction pathways contributing to LMNA laminopathies; Opioid receptor pathways; 15q11q13 copy number variation; Notch signaling pathway; Sudden infant death syndrome (SIDS) susceptibility pathways"	"54"	"0"	"381.0"	"133.5"	"323.8"	"345.1"	"340.0"	"436.6"	"324.1"	"450.8"	"296.3"	"574.8"	"1020.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13646"	"Keratin, type I cytoskeletal 13 OS=Homo sapiens OX=9606 GN=KRT13 PE=1 SV=4"	"0.000"	""	"7"	"3"	"6"	"1"	"458"	"49.6"	"4.96"	"1336.84"	"7.63"	"3"	"1"	"cell organization and biogenesis;stress response;other biological processes"	"cytosol;cytoskeleton"	"other molecular function"	"Pf00038"	"3860"	"ENSG00000171401"	"KRT13"	"hsa:3860; P13646; Q53G54; Q6AZK5; Q8N240"	"Formation of the cornified envelope"	"Vitamin D receptor pathway"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P37198"	"Nuclear pore glycoprotein p62 OS=Homo sapiens OX=9606 GN=NUP62 PE=1 SV=3"	"0.000"	""	"5"	"2"	"4"	"2"	"522"	"53.2"	"5.31"	"806.85"	"7.62"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"other membranes;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf05064"	"23636"	"ENSG00000213024"	"NUP62"	"B3KWU5; hsa:23636; P37198; Q503A4; Q6GTM2; Q96C43; Q9NSL1"	"Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Regulation of HSF1-mediated heat shock response; Nuclear Pore Complex (NPC) Disassembly; HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Postmitotic nuclear pore complex (NPC) reformation"	"7q11.23 copy number variation syndrome"	"30"	"0"	"113.4"	"36.2"	"91.2"	"68.2"	"79.2"	"92.6"	"78.1"	"103.7"	"116.0"	"209.1"	"274.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5RKV6"	"Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1"	"0.000"	""	"10"	"3"	"5"	"3"	"272"	"28.2"	"6.28"	"694.44"	"7.60"	"2"	"3"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	""	"Pf01138"	"118460"	"ENSG00000223496"	"EXOSC6"	"hsa:118460; Q5RKV6"	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	""	"6"	"0"	"292.4"	"130.1"	"263.7"	"260.7"	"275.6"	"307.8"	"235.3"	"354.3"	"301.5"	"639.1"	"978.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IWI9"	"MAX gene-associated protein OS=Homo sapiens OX=9606 GN=MGA PE=1 SV=4"	"0.000"	""	"1"	"3"	"6"	"3"	"3065"	"336.0"	"6.90"	"778.37"	"7.58"	"3"	"3"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00010, Pf00907, Pf16059"	"23269"	"ENSG00000174197"	"MGA"	"B9EGR5; E7ENI0; F5H7K2; hsa:23269; Q8IWI9; Q9H8R3; Q9H9N7; Q9UG69; Q9Y4E9"	"Transcriptional Regulation by E2F6"	"Pathways affected in adenoid cystic carcinoma"	"2"	"0"	"102.9"	"45.0"	"87.7"	"87.3"	"84.6"	"104.1"	"71.0"	"81.1"	"69.1"	"121.4"	"145.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35580"	"Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3"	"0.000"	""	"2"	"4"	"6"	"3"	"1976"	"228.9"	"5.54"	"1710.29"	"7.55"	"4"	"2"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00063, Pf00612, Pf01576, Pf02736"	"4628"	"ENSG00000133026"	"MYH10"	"B2RWP9; D3DTS1; F8VTL3; hsa:4628; P35580; Q12989; Q149N3; Q149N4; Q16087; Q4LE45; Q6PK16; Q9BWG0"	"EPHA-mediated growth cone collapse; RHO GTPases activate PAKs; RHO GTPases activate CIT; Sema4D induced cell migration and growth-cone collapse; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs"	"Regulation of actin cytoskeleton"	"7"	"1"	"445.0"	"130.8"	"294.5"	"238.1"	"341.3"	"345.3"	"256.0"	"382.8"	"259.7"	"444.3"	"751.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75438"	"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 OS=Homo sapiens OX=9606 GN=NDUFB1 PE=1 SV=1"	"0.000"	""	"21"	"2"	"3"	"2"	"58"	"7.0"	"8.92"	"470.63"	"7.55"	"1"	"2"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion;nucleus"	"transporter activity"	"Pf08040"	"4707"	"ENSG00000183648"	"NDUFB1"	"A0AV68; hsa:4707; O75438"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"5"	"0"	"95.0"	"31.3"	"71.5"	"56.8"	"66.4"	"74.4"	"62.6"	"88.1"	"64.7"	"158.5"	"324.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82650"	"28S ribosomal protein S22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS22 PE=1 SV=1"	"0.000"	""	"5"	"2"	"6"	"2"	"360"	"41.3"	"7.90"	"880.90"	"7.55"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf10245"	"56945"	"ENSG00000175110"	"MRPS22"	"hsa:56945; P82650; Q9H3I1"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"Primary ovarian insufficiency"	"4"	"0"	"341.1"	"138.5"	"256.5"	"230.0"	"263.5"	"314.7"	"233.7"	"299.0"	"239.8"	"398.2"	"706.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NSY1"	"BMP-2-inducible protein kinase OS=Homo sapiens OX=9606 GN=BMP2K PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"1161"	"129.1"	"6.51"	"321.92"	"7.55"	"1"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf15282"	"55589"	"ENSG00000138756"	"BMP2K"	"hsa:55589; O94791; Q4W5H2; Q8IYF2; Q8N2G7; Q8NHG9; Q9NSY1; Q9NTG8"	""	""	"0"	"0"	"53.7"	"20.2"	"47.4"	"38.3"	"42.1"	"54.8"	"41.5"	"51.1"	"47.1"	"76.5"	"130.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BTE3"	"Mini-chromosome maintenance complex-binding protein OS=Homo sapiens OX=9606 GN=MCMBP PE=1 SV=2"	"0.000"	""	"7"	"2"	"3"	"2"	"642"	"72.9"	"5.87"	"312.31"	"7.54"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf09739"	"79892"	"ENSG00000197771"	"MCMBP"	"B3KSP7; hsa:79892; Q6IA56; Q9BTE3; Q9BVT9; Q9H916"	""	""	"0"	"0"	"69.3"	"46.1"	"53.0"	"52.3"	"67.6"	"63.5"	"55.4"	"65.8"	"49.1"	"97.6"	"129.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P78332"	"RNA-binding protein 6 OS=Homo sapiens OX=9606 GN=RBM6 PE=1 SV=5"	"0.000"	""	"2"	"3"	"6"	"3"	"1123"	"128.6"	"6.32"	"873.90"	"7.54"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf01585, Pf17780"	"10180"	"ENSG00000004534"	"RBM6"	"B4E0G6; hsa:10180; O60549; O75524; P78332; Q86SS3"	""	""	"0"	"0"	"393.5"	"182.9"	"281.6"	"264.5"	"293.4"	"312.1"	"259.6"	"334.4"	"312.7"	"509.2"	"778.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15118"	"[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial OS=Homo sapiens OX=9606 GN=PDK1 PE=1 SV=1"	"0.000"	""	"7"	"2"	"4"	"2"	"436"	"49.2"	"8.81"	"763.66"	"7.52"	"2"	"2"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"mitochondrion"	"kinase activity;other molecular function"	"Pf02518, Pf10436"	"5163"	"ENSG00000152256"	"PDK1"	"B2R6T1; B7Z937; D3DPD8; E9PD65; hsa:5163; Q15118; Q308M4"	"Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid"	"T cell receptor and co-stimulatory signaling; PI3K-AKT-mTOR signaling pathway and therapeutic opportunities in prostate cancer; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; Non-small cell lung cancer; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Aspirin and miRNAs; PKC-gamma calcium signaling pathway in ataxia; Kisspeptin/kisspeptin receptor system in the ovary; TCA cycle in senescence; Pleural mesothelioma; Orexin receptor pathway; Resolvin E1 and resolvin D1 signaling pathways promoting inflammation resolution; Glucose metabolism in triple-negative breast cancer cells; EPO receptor signaling; DNA damage response (only ATM dependent)"	"19"	"0"	"59.2"	"36.2"	"53.9"	"51.9"	"46.3"	"55.9"	"47.3"	"59.0"	"74.3"	"170.5"	"310.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P36542"	"ATP synthase subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1C PE=1 SV=1"	"0.000"	""	"12"	"4"	"6"	"4"	"298"	"33.0"	"9.22"	"716.46"	"7.52"	"3"	"2"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf00231"	"509"	"ENSG00000165629"	"ATP5F1C"	"A8KA31; hsa:509; P36542; Q5VYP3; Q6I9V2; Q96AS8"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"Electron transport chain: OXPHOS system in mitochondria"	"3"	"0"	"297.1"	"94.4"	"177.8"	"147.7"	"192.3"	"202.7"	"194.3"	"273.5"	"255.8"	"559.3"	"1292.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P41214"	"Eukaryotic translation initiation factor 2D OS=Homo sapiens OX=9606 GN=EIF2D PE=1 SV=3"	"0.000"	""	"6"	"2"	"3"	"2"	"584"	"64.7"	"7.65"	"403.80"	"7.51"	"1"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01253, Pf17832"	"1939"	"ENSG00000143486"	"EIF2D"	"hsa:1939; P41214; Q5SY40; Q8IXV3; Q96DG3; Q96TG7; Q9NR27; Q9NSN0; Q9NV18; Q9NZ21"	""	""	"0"	"0"	"30.1"	"10.7"	"23.4"	"21.7"	"24.8"	"27.1"	"19.3"	"27.8"	"18.1"	"61.5"	"167.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22087"	"rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2"	"0.000"	""	"6"	"3"	"6"	"3"	"321"	"33.8"	"10.18"	"959.16"	"7.50"	"3"	"3"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf01269"	"2091"	"ENSG00000105202; ENSG00000280548"	"FBL"	"B5BUE8; hsa:2091; O75259; P22087; Q6IAT5; Q9UPI6"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	"310.8"	"132.5"	"257.0"	"264.6"	"262.4"	"303.8"	"208.4"	"313.6"	"381.0"	"1070.9"	"1438.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q3SYG4"	"Protein PTHB1 OS=Homo sapiens OX=9606 GN=BBS9 PE=1 SV=1"	"0.000"	""	"3"	"2"	"4"	"2"	"887"	"99.2"	"5.55"	"751.24"	"7.50"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	""	"Pf14727, Pf14728"	"27241"	"ENSG00000122507"	"BBS9"	"E9PDC9; hsa:27241; P78514; Q3SYG4; Q7KYS6; Q7KYS7; Q8N570; Q99844; Q99854; Q9Y699; Q9Y6A0"	"BBSome-mediated cargo-targeting to cilium"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies; Bardet-Biedl syndrome"	"6"	"0"	"30.5"	"17.5"	"26.8"	"23.3"	"32.3"	"26.3"	"29.0"	"60.3"	"95.7"	"278.4"	"423.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13769"	"THO complex subunit 5 homolog OS=Homo sapiens OX=9606 GN=THOC5 PE=1 SV=2"	"0.001"	""	"5"	"3"	"4"	"3"	"683"	"78.5"	"6.87"	"263.82"	"7.49"	"1"	"3"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf09766"	"8563"	"ENSG00000100296"	"THOC5"	"hsa:8563; O60839; Q13769; Q9UPZ5"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Signaling by CSF1 (M-CSF) in myeloid cells"	""	"4"	"0"	"203.0"	"80.0"	"173.7"	"127.9"	"159.4"	"174.0"	"142.2"	"176.0"	"182.9"	"348.2"	"577.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62312"	"U6 snRNA-associated Sm-like protein LSm6 OS=Homo sapiens OX=9606 GN=LSM6 PE=1 SV=1"	"0.000"	""	"33"	"3"	"5"	"3"	"80"	"9.1"	"9.58"	"534.24"	"7.48"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01423"	"11157"	"ENSG00000164167"	"LSM6"	"hsa:11157; P62312; Q4W5J5; Q9Y4Y8"	"mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease"	""	"2"	"0"	"909.8"	"309.8"	"614.5"	"520.6"	"678.4"	"729.4"	"593.5"	"818.7"	"645.8"	"929.2"	"1325.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HCS7"	"Pre-mRNA-splicing factor SYF1 OS=Homo sapiens OX=9606 GN=XAB2 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"855"	"99.9"	"6.23"	"805.75"	"7.47"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes"	"nucleus;other cell component"	""	"Pf13181"	"56949"	"ENSG00000076924"	"XAB2"	"hsa:56949; Q8TET6; Q96HB0; Q96IW0; Q9HCS7; Q9NRG6; Q9ULP3"	"mRNA Splicing - Major Pathway; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	"Rett syndrome causing genes; Nucleotide excision repair in xeroderma pigmentosum"	"7"	"0"	"155.4"	"55.9"	"155.8"	"139.7"	"146.8"	"143.5"	"106.1"	"131.4"	"93.0"	"178.2"	"328.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q56P03"	"E2F-associated phosphoprotein OS=Homo sapiens OX=9606 GN=EAPP PE=1 SV=4"	"0.000"	""	"9"	"2"	"4"	"2"	"285"	"32.7"	"5.12"	"769.77"	"7.46"	"2"	"2"	"other biological processes"	"nucleus;other cell component"	""	"Pf10238"	"55837"	"ENSG00000129518"	"EAPP"	"hsa:55837; Q56P03; Q9BVF4; Q9NWV5; Q9NZ86"	""	""	"0"	"0"	"101.1"	"44.1"	"87.4"	"82.3"	"96.1"	"101.7"	"75.8"	"99.8"	"88.4"	"185.1"	"415.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23919"	"Thymidylate kinase OS=Homo sapiens OX=9606 GN=DTYMK PE=1 SV=4"	"0.000"	""	"11"	"2"	"6"	"2"	"212"	"23.8"	"8.27"	"880.16"	"7.46"	"2"	"2"	"other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf02223"	"1841"	"ENSG00000168393"	"DTYMK"	"B7ZW70; hsa:1841; P23919; Q6FGX1; Q9BUX4"	"Interconversion of nucleotide di- and triphosphates"	"Pyrimidine metabolism; 2q37 copy number variation syndrome"	"3"	"0"	"39.2"	"15.8"	"31.7"	"22.0"	"31.5"	"34.0"	"26.3"	"33.8"	"34.9"	"69.1"	"125.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62306"	"Small nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=SNRPF PE=1 SV=1"	"0.000"	""	"15"	"1"	"4"	"1"	"86"	"9.7"	"4.67"	"874.52"	"7.45"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	"6636"	"ENSG00000139343"	"SNRPF"	"A2VCR2; B2R498; hsa:6636; P62306; Q15356; Q6IBQ1; Q6P4I0"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; RNA Polymerase II Transcription Termination; SARS-CoV-2 modulates host translation machinery; snRNP Assembly; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"mRNA processing"	"8"	"0"	"76.9"	"28.1"	"41.6"	"34.0"	"49.5"	"50.3"	"38.6"	"57.9"	"67.3"	"90.4"	"125.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13620"	"Cullin-4B OS=Homo sapiens OX=9606 GN=CUL4B PE=1 SV=4"	"0.000"	""	"3"	"2"	"4"	"1"	"913"	"103.9"	"7.37"	"882.88"	"7.44"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00888, Pf10557"	"8450"	"ENSG00000158290"	"CUL4B"	"B1APK5; B3KVX4; B7Z5K8; hsa:8450; Q13620; Q6PIE4; Q6UP07; Q7Z673; Q9BY37; Q9UEB7; Q9UED7"	"Formation of Incision Complex in GG-NER; DNA Damage Recognition in GG-NER; Neddylation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Recognition of DNA damage by PCNA-containing replication complex; Dual Incision in GG-NER"	"Mesodermal commitment pathway; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"13"	"1"	"97.6"	"39.9"	"81.8"	"78.7"	"76.3"	"90.5"	"75.8"	"86.5"	"83.3"	"188.7"	"585.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15504"	"Nucleoporin NUP42 OS=Homo sapiens OX=9606 GN=NUP42 PE=1 SV=1"	"0.000"	""	"6"	"2"	"4"	"2"	"423"	"44.8"	"9.19"	"745.26"	"7.44"	"2"	"2"	"transport"	"other membranes;cytosol;nucleus"	"other molecular function"	""	"11097"	"ENSG00000136243"	"NUP42"	"A4D143; B4DP42; hsa:11097; O15504; Q49AE7; Q9BS49"	"HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	""	"28"	"0"	"236.6"	"86.7"	"180.8"	"143.2"	"169.9"	"174.0"	"139.7"	"171.5"	"129.6"	"257.2"	"416.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P00403"	"Cytochrome c oxidase subunit 2 OS=Homo sapiens OX=9606 GN=MT-CO2 PE=1 SV=1"	"0.000"	""	"12"	"2"	"4"	"2"	"227"	"25.5"	"4.82"	"847.40"	"7.44"	"2"	"2"	"other metabolic processes;stress response;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00116, Pf02790"	"4513"	"ENSG00000198712"	"MT-CO2"	"hsa:4513; P00403; Q37526"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"Electron transport chain: OXPHOS system in mitochondria; Endothelin pathways; EGF/EGFR signaling pathway; Nonalcoholic fatty liver disease; Neuroinflammation; Mitochondrial complex IV assembly; CCL18 signaling pathway; 5q35 copy number variation"	"11"	"0"	"134.6"	"44.1"	"79.9"	"67.8"	"86.9"	"81.8"	"87.1"	"101.4"	"137.7"	"184.8"	"394.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96PY5"	"Formin-like protein 2 OS=Homo sapiens OX=9606 GN=FMNL2 PE=1 SV=3"	"0.000"	""	"2"	"2"	"6"	"2"	"1086"	"123.2"	"7.40"	"934.85"	"7.42"	"2"	"2"	"cell organization and biogenesis;other biological processes"	"cytosol"	"cytoskeletal activity;other molecular function"	"Pf02181, Pf06367, Pf06371"	"114793"	"ENSG00000157827"	"FMNL2"	"B2RZH5; hsa:114793; Q14CC9; Q4ZG52; Q8N3E0; Q96PY5"	"RHOC GTPase cycle; CDC42 GTPase cycle; RHO GTPases Activate Formins"	"Epithelial to mesenchymal transition in colorectal cancer"	"4"	"0"	"90.4"	"24.9"	"68.2"	"73.4"	"72.3"	"83.0"	"57.5"	"83.5"	"57.1"	"280.1"	"329.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92979"	"Ribosomal RNA small subunit methyltransferase NEP1 OS=Homo sapiens OX=9606 GN=EMG1 PE=1 SV=4"	"0.000"	""	"13"	"2"	"3"	"2"	"244"	"26.7"	"9.17"	"678.84"	"7.42"	"1"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03587"	"10436"	"ENSG00000126749"	"EMG1"	"hsa:10436; O00675; O00726; Q92979"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	"18.2"	"8.6"	"13.3"	"16.0"	"12.0"	"15.3"	"14.3"	"18.8"	"22.7"	"45.5"	"68.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BUR4"	"Telomerase Cajal body protein 1 OS=Homo sapiens OX=9606 GN=WRAP53 PE=1 SV=1"	"0.000"	""	"6"	"2"	"4"	"2"	"548"	"59.3"	"4.58"	"752.77"	"7.42"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400"	"55135"	"ENSG00000141499"	"WRAP53"	"B3KPR9; D3DTQ4; hsa:55135; Q08ET9; Q9BUR4; Q9NW09"	"Association of TriC/CCT with target proteins during biosynthesis; Telomere Extension By Telomerase"	""	"2"	"0"	"43.1"	"14.3"	"34.6"	"35.1"	"37.9"	"44.0"	"35.0"	"47.7"	"37.4"	"100.3"	"192.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26196"	"Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2"	"0.000"	""	"7"	"3"	"5"	"3"	"483"	"54.4"	"8.66"	"1247.81"	"7.40"	"3"	"2"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"1656"	"ENSG00000110367"	"DDX6"	"hsa:1656; P26196; Q5D048"	"mRNA decay by 5' to 3' exoribonuclease"	""	"1"	"0"	"324.2"	"103.0"	"277.5"	"245.4"	"262.4"	"324.5"	"229.9"	"275.2"	"223.8"	"446.5"	"592.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9BYD6"	"39S ribosomal protein L1, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL1 PE=1 SV=2"	""	""	"14"	"2"	"2"	"2"	"325"	"36.9"	"8.78"	""	"7.40"	""	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00687"	"65008"	"ENSG00000169288"	"MRPL1"	"A6NG03; hsa:65008; Q4W5B8; Q6IAG4; Q96BW3; Q9BYD6; Q9H793; Q9NRL5"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"38.1"	"13.9"	"34.7"	"24.6"	"26.2"	"30.5"	"24.4"	"33.8"	"34.1"	"95.1"	"200.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92621"	"Nuclear pore complex protein Nup205 OS=Homo sapiens OX=9606 GN=NUP205 PE=1 SV=3"	"0.000"	""	"1"	"2"	"3"	"2"	"2012"	"227.8"	"6.19"	"362.15"	"7.37"	"1"	"2"	"cell organization and biogenesis;transport"	"other membranes;cytosol;nucleus"	"other molecular function"	"Pf11894"	"23165"	"ENSG00000155561"	"NUP205"	"A6H8X3; hsa:23165; Q86YC1; Q92621"	"HCMV Early Events; Rev-mediated nuclear export of HIV RNA; Nuclear import of Rev protein; Postmitotic nuclear pore complex (NPC) reformation; HCMV Late Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	""	"29"	"0"	"37.4"	"9.7"	"23.9"	"22.5"	"28.5"	"29.5"	"26.4"	"31.4"	"26.6"	"60.2"	"182.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12959"	"Disks large homolog 1 OS=Homo sapiens OX=9606 GN=DLG1 PE=1 SV=2"	"0.000"	""	"4"	"2"	"4"	"2"	"904"	"100.4"	"5.76"	"860.03"	"7.37"	"2"	"2"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"extracellular matrix;plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00018, Pf00595, Pf00625, Pf09058, Pf10600, Pf10608"	"1739"	"ENSG00000075711"	"DLG1"	"A5YKK7; B4DGU1; B4DGZ8; B7ZMM0; B9EIQ5; D3DXB8; D3DXB9; E7EWL7; E9PG21; hsa:1739; Q12958; Q12959"	"Assembly and cell surface presentation of NMDA receptors; RAF/MAP kinase cascade; Ras activation upon Ca2+ influx through NMDA receptor; Unblocking of NMDA receptors, glutamate binding and activation; Synaptic adhesion-like molecules; Negative regulation of NMDA receptor-mediated neuronal transmission; Long-term potentiation; Trafficking of AMPA receptors; NrCAM interactions; Activation of Ca-permeable Kainate Receptor"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; Disruption of postsynaptic signaling by CNV; 3q29 copy number variation syndrome"	"14"	"0"	"46.5"	"16.2"	"46.3"	"31.4"	"45.6"	"44.7"	"34.5"	"49.3"	"39.4"	"92.0"	"198.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13554"	"Calcium/calmodulin-dependent protein kinase type II subunit beta OS=Homo sapiens OX=9606 GN=CAMK2B PE=1 SV=3"	"0.000"	""	"5"	"2"	"4"	"1"	"666"	"72.6"	"7.27"	"812.72"	"7.36"	"2"	"2"	"protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00069, Pf08332"	"816"	"ENSG00000058404"	"CAMK2B"	"A4D2K0; A4D2K1; A4D2K2; A4D2K3; A4D2K4; A4D2K5; A4D2K6; hsa:816; O95437; O95438; O95599; Q13554; Q9UGH7; Q9UGH8; Q9UGH9; Q9UNX0; Q9UNX7; Q9UP00; Q9Y5N4; Q9Y6F4"	"Signaling by BRAF and RAF1 fusions; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; Assembly and cell surface presentation of NMDA receptors; Ion homeostasis; Ion transport by P-type ATPases; Interferon gamma signaling; RAF activation; Ras activation upon Ca2+ influx through NMDA receptor; Regulation of MECP2 expression and activity; Unblocking of NMDA receptors, glutamate binding and activation; Negative regulation of NMDA receptor-mediated neuronal transmission; Long-term potentiation; Trafficking of AMPA receptors; Phase 0 - rapid depolarisation; HSF1-dependent transactivation; CaMK IV-mediated phosphorylation of CREB; CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde"	"Primary focal segmental glomerulosclerosis (FSGS); Myometrial relaxation and contraction pathways; Serotonin and anxiety; NO/cGMP/PKG mediated neuroprotection; Wnt signaling; Non-genomic actions of 1,25 dihydroxyvitamin D3; Synaptic signaling pathways associated with autism spectrum disorder; Fragile X syndrome; Disruption of postsynaptic signaling by CNV; Neuroinflammation and glutamatergic signaling; GDNF signaling; Hippocampal synaptogenesis and neurogenesis; Calcium regulation in cardiac cells; ErbB signaling pathway"	"35"	"1"	"148.0"	"52.3"	"88.2"	"75.4"	"87.4"	"105.3"	"86.9"	"117.3"	"118.9"	"182.5"	"343.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2X3"	"Nucleolar protein 58 OS=Homo sapiens OX=9606 GN=NOP58 PE=1 SV=1"	"0.000"	""	"6"	"2"	"4"	"2"	"529"	"59.5"	"8.92"	"706.23"	"7.35"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01798, Pf08156"	"51602"	"ENSG00000055044"	"NOP58"	"hsa:51602; Q53SA4; Q6PK08; Q9P036; Q9UFN3; Q9Y2X3"	"Major pathway of rRNA processing in the nucleolus and cytosol; SUMOylation of RNA binding proteins; rRNA modification in the nucleus and cytosol"	""	"3"	"0"	"60.6"	"31.7"	"54.8"	"39.4"	"64.9"	"65.9"	"52.3"	"66.4"	"74.3"	"179.3"	"329.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TF01"	"Arginine/serine-rich protein PNISR OS=Homo sapiens OX=9606 GN=PNISR PE=1 SV=2"	"0.000"	""	"3"	"3"	"5"	"3"	"805"	"92.5"	"10.02"	"1189.94"	"7.35"	"3"	"2"	""	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	""	"Pf15996"	"25957"	"ENSG00000132424"	"PNISR"	"A8K540; E1P5D2; hsa:25957; Q5T064; Q5T065; Q6P2B4; Q6P2N4; Q6PJ93; Q6PK36; Q7Z640; Q8N2L1; Q8TF00; Q8TF01; Q96K10; Q96SI3; Q96SM5; Q9P076; Q9P0C0; Q9Y4N3"	""	""	"0"	"0"	"393.6"	"166.4"	"303.9"	"259.0"	"311.6"	"322.5"	"248.6"	"342.0"	"295.2"	"479.5"	"771.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P15927"	"Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1"	""	""	"10"	"2"	"2"	"2"	"270"	"29.2"	"6.15"	""	"7.30"	""	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf08784"	"6118"	"ENSG00000117748"	"RPA2"	"hsa:6118; P15927; Q52II0; Q5TEI9; Q5TEJ5"	"Regulation of HSF1-mediated heat shock response; Fanconi Anemia Pathway; Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Meiotic recombination; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; HSF1 activation; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Removal of the Flap Intermediate; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"miRNA regulation of DNA damage response; Retinoblastoma gene in cancer; G1 to S cell cycle control; DNA replication; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair; DNA damage response"	"38"	"0"	"123.5"	"37.4"	"107.4"	"83.9"	"122.4"	"137.4"	"104.4"	"126.6"	"95.8"	"182.7"	"462.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13084"	"39S ribosomal protein L28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL28 PE=1 SV=4"	"0.001"	""	"11"	"2"	"3"	"2"	"256"	"30.1"	"8.29"	"253.52"	"7.28"	"1"	"2"	"protein metabolism;other metabolic processes"	"other membranes;cytosol;mitochondrion;translational apparatus"	"other molecular function"	"Pf00830"	"10573"	"ENSG00000086504"	"MRPL28"	"B2RCM4; D3DU46; hsa:10573; Q13084; Q4TT39; Q96S26; Q9BQD8; Q9BR04"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"193.1"	"83.6"	"150.9"	"110.0"	"128.3"	"153.6"	"122.0"	"170.0"	"119.7"	"233.1"	"436.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35658"	"Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2"	"0.000"	""	"2"	"3"	"5"	"3"	"2090"	"213.5"	"7.47"	"1058.84"	"7.28"	"3"	"2"	"cell cycle OR cell proliferation;other metabolic processes;transport;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf18617"	"8021"	"ENSG00000126883"	"NUP214"	"A6NFQ0; hsa:8021; P35658; Q15010; Q3KQZ0; Q5JUP7; Q75R47; Q86XD3"	"HCMV Early Events; Rev-mediated nuclear export of HIV RNA; Nuclear import of Rev protein; HCMV Late Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; HuR (ELAVL1) binds and stabilizes mRNA"	""	"29"	"0"	"397.4"	"140.4"	"313.2"	"277.3"	"308.5"	"331.7"	"237.3"	"321.3"	"240.6"	"614.8"	"1312.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q68CQ4"	"Digestive organ expansion factor homolog OS=Homo sapiens OX=9606 GN=DIEXF PE=1 SV=2"	"0.000"	""	"6"	"5"	"8"	"5"	"756"	"87.0"	"5.88"	"1324.30"	"7.25"	"5"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf06862"	"27042"	"ENSG00000117597"	"UTP25"	"hsa:27042; O75992; Q4VY00; Q63HL9; Q68CQ4"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	"131.6"	"69.3"	"139.4"	"135.5"	"123.4"	"152.7"	"132.7"	"217.0"	"169.9"	"276.5"	"331.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P6C2"	"RNA demethylase ALKBH5 OS=Homo sapiens OX=9606 GN=ALKBH5 PE=1 SV=2"	"0.000"	""	"5"	"2"	"3"	"2"	"394"	"44.2"	"9.09"	"407.48"	"7.24"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;ER/Golgi;nucleus"	"other molecular function"	"Pf13532"	"54890"	"ENSG00000091542"	"ALKBH5"	"B4DVJ4; D3DXC6; hsa:54890; Q6P6C2; Q9NXD6"	"Reversal of alkylation damage by DNA dioxygenases"	"Smith-Magenis and Potocki-Lupski syndrome copy number variation"	"2"	"0"	"22.9"	"9.5"	"16.9"	"12.4"	"18.0"	"18.2"	"14.7"	"18.0"	"19.1"	"31.3"	"43.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14635"	"G2/mitotic-specific cyclin-B1 OS=Homo sapiens OX=9606 GN=CCNB1 PE=1 SV=1"	"0.000"	""	"5"	"2"	"4"	"2"	"433"	"48.3"	"7.47"	"861.87"	"7.23"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00134, Pf02984"	"891"	"ENSG00000134057"	"CCNB1"	"A8K066; hsa:891; P14635; Q5TZP9"	"The role of GTSE1 in G2/M progression after G2 checkpoint; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Resolution of Sister Chromatid Cohesion; Nuclear Pore Complex (NPC) Disassembly; Regulation of PLK1 Activity at G2/M Transition; APC/C:Cdc20 mediated degradation of Cyclin B; Phosphorylation of the APC/C; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; Cyclin A/B1/B2 associated events during G2/M transition; Transcriptional regulation by RUNX2; MASTL Facilitates Mitotic Progression; E2F-enabled inhibition of pre-replication complex formation; Golgi Cisternae Pericentriolar Stack Reorganization; Condensation of Prophase Chromosomes; Initiation of Nuclear Envelope (NE) Reformation; Polo-like kinase mediated events; Condensation of Prometaphase Chromosomes; Activation of NIMA Kinases NEK9, NEK6, NEK7; G2/M DNA replication checkpoint; Depolymerization of the Nuclear Lamina; Phosphorylation of Emi1"	"AMP-activated protein kinase signaling; miRNA regulation of DNA damage response; Cell cycle; Retinoblastoma gene in cancer; ATM signaling pathway; G1 to S cell cycle control; GDNF signaling; DNA damage response"	"31"	"0"	"107.5"	"40.1"	"103.8"	"85.0"	"92.7"	"118.8"	"67.9"	"116.1"	"103.1"	"197.2"	"607.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62899"	"60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1"	"0.000"	""	"18"	"2"	"4"	"2"	"125"	"14.5"	"10.54"	"685.90"	"7.18"	"2"	"2"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01198"	"6160"	"ENSG00000071082"	"RPL31"	"B7Z4K2; D3DVJ4; hsa:6160; P12947; P62899; Q53SQ5; Q6IRZ0; Q6LBJ6"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"352.3"	"125.2"	"256.1"	"229.1"	"259.7"	"317.7"	"228.2"	"322.0"	"215.3"	"357.0"	"454.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62244"	"40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2"	"0.000"	""	"25"	"4"	"7"	"4"	"130"	"14.8"	"10.13"	"1172.34"	"7.18"	"4"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00410"	"6210"	"ENSG00000134419"	"RPS15A"	"hsa:6210; P39027; P39031; P62244; Q3MHD9; Q8C023; Q9BV24"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Response of EIF2AK4 (GCN2) to amino acid deficiency; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"606.7"	"277.7"	"484.9"	"518.0"	"517.6"	"689.3"	"548.9"	"521.8"	"463.7"	"752.1"	"909.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00139"	"Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3"	"0.000"	""	"4"	"3"	"5"	"3"	"706"	"79.9"	"6.68"	"1077.18"	"7.17"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225"	"3796"	"ENSG00000068796"	"KIF2A"	"A5YM42; A5YM54; B4DY54; D3DW97; E9PB70; hsa:3796; O00139; Q7Z5I3; Q8N5Q7"	"COPI-dependent Golgi-to-ER retrograde traffic; Separation of Sister Chromatids; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Kinesins; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	""	"9"	"0"	"303.4"	"118.2"	"298.6"	"263.4"	"287.9"	"317.8"	"194.2"	"284.3"	"204.2"	"492.0"	"1457.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42696"	"RNA-binding protein 34 OS=Homo sapiens OX=9606 GN=RBM34 PE=1 SV=2"	"0.000"	""	"7"	"2"	"3"	"2"	"430"	"48.5"	"10.11"	"334.61"	"7.16"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"23029"	"ENSG00000188739"	"RBM34"	"A8K8J7; hsa:23029; P42696; Q8N2Z8; Q9H5A1"	""	""	"0"	"0"	"137.6"	"54.3"	"103.0"	"95.1"	"93.6"	"121.0"	"86.0"	"112.7"	"99.7"	"243.2"	"474.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13425"	"Beta-2-syntrophin OS=Homo sapiens OX=9606 GN=SNTB2 PE=1 SV=1"	"0.000"	""	"3"	"2"	"6"	"2"	"540"	"57.9"	"8.82"	"995.06"	"7.16"	"2"	"2"	""	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00595, Pf18012"	"6645"	"ENSG00000168807"	"SNTB2"	"hsa:6645; Q13425; Q9BY09"	""	""	"0"	"0"	"286.4"	"119.9"	"226.7"	"151.9"	"189.7"	"251.4"	"169.7"	"241.3"	"202.2"	"369.4"	"682.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99959"	"Plakophilin-2 OS=Homo sapiens OX=9606 GN=PKP2 PE=1 SV=2"	"0.000"	""	"6"	"6"	"8"	"5"	"881"	"97.4"	"9.33"	"1450.74"	"7.15"	"5"	"3"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00514"	"5318"	"ENSG00000057294"	"PKP2"	"A0AV37; B8QFA1; B8QGS6; B8QGS7; D3DUW9; hsa:5318; Q4VC01; Q99959; Q99960"	"Formation of the cornified envelope"	"Arrhythmogenic right ventricular cardiomyopathy; Epithelial to mesenchymal transition in colorectal cancer"	"4"	"1"	"529.7"	"185.5"	"366.8"	"328.3"	"402.3"	"407.5"	"277.8"	"442.0"	"360.2"	"859.9"	"1765.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UDY4"	"DnaJ homolog subfamily B member 4 OS=Homo sapiens OX=9606 GN=DNAJB4 PE=1 SV=1"	"0.000"	""	"9"	"2"	"4"	"1"	"337"	"37.8"	"8.50"	"659.81"	"7.15"	"2"	"2"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	"other molecular function"	"Pf00226, Pf01556"	"11080"	"ENSG00000162616"	"DNAJB4"	"B2R824; hsa:11080; Q13431; Q9UDY4"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"19.7"	"5.6"	"20.5"	"15.4"	"17.0"	"20.8"	"18.8"	"20.6"	"14.5"	"23.4"	"42.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14677"	"Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1"	"0.000"	""	"4"	"2"	"6"	"2"	"625"	"68.2"	"6.42"	"731.78"	"7.15"	"2"	"2"	"transport"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01417"	"9685"	"ENSG00000113282"	"CLINT1"	"B7Z6F8; D3DQJ6; hsa:9685; Q14677; Q8NAF1; Q96E05"	"Golgi Associated Vesicle Biogenesis"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6GYQ0"	"Ral GTPase-activating protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=RALGAPA1 PE=1 SV=1"	"0.000"	""	"1"	"2"	"3"	"2"	"2036"	"229.7"	"6.19"	"392.51"	"7.14"	"1"	"2"	"other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02145, Pf20412"	"253959"	"ENSG00000174373"	"RALGAPA1"	"A6NMA4; B9EK38; C5NU19; hsa:253959; O94960; Q6GYP9; Q6GYQ0; Q6ZT23; Q86YF3; Q86YF5; Q8ND69"	"RHOH GTPase cycle"	""	"1"	"0"	"5.8"	"4.6"	"7.2"	"3.6"	"4.9"	"5.0"	"8.6"	"9.2"	"14.8"	"41.8"	"124.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13555"	"Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens OX=9606 GN=CAMK2G PE=1 SV=4"	"0.000"	""	"5"	"2"	"4"	"1"	"558"	"62.6"	"7.83"	"788.43"	"7.11"	"2"	"2"	"cell-cell signaling;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf08332"	"818"	"ENSG00000148660"	"CAMK2G"	"A0A0A0MS52; A0A0A0MT11; hsa:818; O00561; O15378; Q13279; Q13282; Q13555; Q13556; Q5SQZ3; Q5SQZ4; Q5SWX4; Q7KYX5; Q8N4I3; Q8NIA4"	"Signaling by BRAF and RAF1 fusions; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; Assembly and cell surface presentation of NMDA receptors; Ion homeostasis; Ion transport by P-type ATPases; Interferon gamma signaling; RAF activation; Ras activation upon Ca2+ influx through NMDA receptor; Regulation of MECP2 expression and activity; Unblocking of NMDA receptors, glutamate binding and activation; Negative regulation of NMDA receptor-mediated neuronal transmission; Long-term potentiation; Trafficking of AMPA receptors; Phase 0 - rapid depolarisation; HSF1-dependent transactivation; CaMK IV-mediated phosphorylation of CREB; CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde"	"Energy metabolism; Myometrial relaxation and contraction pathways; NO/cGMP/PKG mediated neuroprotection; Splicing factor NOVA regulated synaptic proteins; Wnt signaling; Non-genomic actions of 1,25 dihydroxyvitamin D3; Disruption of postsynaptic signaling by CNV; Neuroinflammation and glutamatergic signaling; Calcium regulation in cardiac cells; ErbB signaling pathway"	"31"	"0"	"61.1"	"19.2"	"40.1"	"33.2"	"37.2"	"42.5"	"28.1"	"39.4"	"50.4"	"81.4"	"162.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94813"	"Slit homolog 2 protein OS=Homo sapiens OX=9606 GN=SLIT2 PE=1 SV=1"	"0.000"	""	"3"	"4"	"5"	"4"	"1529"	"169.8"	"7.06"	"1208.60"	"7.11"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;other membranes;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00008, Pf01462, Pf01463, Pf02210, Pf12661, Pf13855"	"9353"	"ENSG00000145147"	"SLIT2"	"A0A0A6YYB8; B7ZLR5; hsa:9353; O94813; O95710; Q17RU3; Q9Y5Q7"	"Regulation of expression of SLITs and ROBOs; Netrin-1 signaling; Inactivation of CDC42 and RAC1; Activation of RAC1; Regulation of commissural axon pathfinding by SLIT and ROBO; Role of ABL in ROBO-SLIT signaling; SLIT2:ROBO1 increases RHOA activity"	"Spinal cord injury; Robo4 and VEGF signaling pathways crosstalk; Genes controlling nephrogenesis; GDNF/RET signaling axis; Development of ureteric collection system"	"13"	"0"	"188.0"	"82.1"	"160.8"	"154.8"	"158.5"	"179.5"	"119.9"	"165.6"	"160.2"	"394.9"	"588.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92599"	"Septin-8 OS=Homo sapiens OX=9606 GN=SEPTIN8 PE=1 SV=4"	"0.000"	""	"5"	"2"	"3"	"1"	"483"	"55.7"	"6.28"	"398.97"	"7.10"	"1"	"2"	"cell cycle OR cell proliferation;other biological processes"	"other membranes;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf00735"	"23176"	"ENSG00000164402"	"SEPTIN8"	"A6NC65; A6NKP6; F6W7K9; hsa:23176; Q8IX36; Q8IX37; Q92599; Q9BVB3"	""	"22q11.2 copy number variation syndrome"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14974"	"Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"876"	"97.1"	"4.78"	"802.10"	"7.10"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;signal transduction;other biological processes"	"non-structural extracellular;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf03810"	"3837"	"ENSG00000108424"	"KPNB1"	"B7ZAV6; D3DTT3; hsa:3837; Q14637; Q14974; Q53XN2; Q96J27"	"Neutrophil degranulation; Assembly of the ORC complex at the origin of replication; ISG15 antiviral mechanism; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Nuclear import of Rev protein; Postmitotic nuclear pore complex (NPC) reformation; Apoptosis induced DNA fragmentation; Interferon alpha/beta signaling; Regulation of cholesterol biosynthesis by SREBP (SREBF); SARS-CoV-1 activates/modulates innate immune responses; Initiation of Nuclear Envelope (NE) Reformation; Inhibition of nitric oxide production"	"Sterol regulatory element-binding proteins (SREBP) signaling; 22q11.2 copy number variation syndrome"	"15"	"0"	"484.1"	"140.8"	"364.4"	"265.0"	"367.9"	"374.8"	"293.3"	"368.3"	"309.9"	"519.3"	"882.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86W42"	"THO complex subunit 6 homolog OS=Homo sapiens OX=9606 GN=THOC6 PE=1 SV=1"	"0.000"	""	"9"	"2"	"4"	"2"	"341"	"37.5"	"7.43"	"843.11"	"7.08"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00400"	"79228"	"ENSG00000131652"	"THOC6"	"B2RA85; hsa:79228; Q86W42; Q8NBR1; Q9BTV9"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript"	""	"3"	"0"	"45.6"	"13.3"	"34.5"	"33.6"	"35.4"	"43.5"	"29.1"	"47.4"	"30.3"	"78.6"	"199.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49327"	"Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3"	"0.000"	""	"1"	"2"	"3"	"2"	"2511"	"273.3"	"6.44"	"302.36"	"7.07"	"1"	"2"	"other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00107, Pf00109, Pf00550, Pf00698, Pf00975, Pf02801, Pf08242, Pf08659, Pf14765, Pf16197"	"2194"	"ENSG00000169710"	"FASN"	"hsa:2194; P49327; Q13479; Q16702; Q4LE83; Q6P4U5; Q6SS02; Q969R1; Q96C68; Q96IT0"	"ChREBP activates metabolic gene expression; Activation of gene expression by SREBF (SREBP); Fatty acyl-CoA biosynthesis; NR1H2 & NR1H3 regulate gene expression linked to lipogenesis; Vitamin B5 (pantothenate) metabolism"	"AMP-activated protein kinase signaling; Sterol regulatory element-binding proteins (SREBP) signaling; SREBF and miR33 in cholesterol and lipid homeostasis; Liver X receptor pathway; Nuclear receptors meta-pathway; Fatty acid biosynthesis; Angiopoietin-like protein 8 regulatory pathway; Lipid metabolism pathway; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Omega-9 fatty acid synthesis; FOXA2 pathway"	"18"	"0"	"21.6"	"8.0"	"16.9"	"16.5"	"18.1"	"14.8"	"19.3"	"20.8"	"16.8"	"31.2"	"61.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y608"	"Leucine-rich repeat flightless-interacting protein 2 OS=Homo sapiens OX=9606 GN=LRRFIP2 PE=1 SV=1"	"0.000"	""	"4"	"2"	"4"	"2"	"721"	"82.1"	"6.95"	"659.91"	"7.07"	"2"	"2"	"cell-cell signaling;signal transduction;other biological processes"	""	"other molecular function"	"Pf09738"	"9209"	"ENSG00000093167"	"LRRFIP2"	"A8K649; A8MXR0; B4DY63; hsa:9209; Q68CV3; Q9NXH5; Q9Y608"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14929"	"Histone acetyltransferase type B catalytic subunit OS=Homo sapiens OX=9606 GN=HAT1 PE=1 SV=1"	"0.000"	""	"7"	"3"	"6"	"3"	"419"	"49.5"	"5.69"	"756.58"	"7.05"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf10394"	"100598934; 100970485; 102127119; 103217315; 104673520; 105548069; 105579802; 695933"	"ENSCATG00000044185; ENSCSAG00000014790; ENSMFAG00000044656; ENSMLEG00000030988; ENSMMUG00000007313; ENSNLEG00000031960; ENSPPAG00000043422; ENSPPYG00000012932; ENSPTEG00000037699; ENSPTRG00000012637; ENSRROG00000043073; ENSTGEG00000018560"	"HAT1"	"A0A0D9RQL6; A0A2I3GP06; A0A2J8PQW8; A0A2J8VQX1; A0A2K5P0H4; A0A2K5VNP4; A0A2K5YDV9; A0A2K6REU7; A0A2R9CI71; A0A663DCK2; A0A6D2WXR9; A0A8C9IWX6; A0A8D2FM88; A0A8J8XV08; A0A8J8YED4; caty:105579802; csab:103217315; F7GNR2; F7GNT9; G7N8B0; G7PKT8; H2P7T9; H2QIZ3; mcc:695933; mcf:102127119; mleu:105548069; nle:100598934; pps:100970485; rro:104673520"	""	""	"0"	"0"	"401.5"	"164.8"	"343.5"	"326.9"	"354.4"	"415.9"	"304.4"	"380.0"	"259.8"	"627.3"	"1254.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P16949"	"Stathmin OS=Homo sapiens OX=9606 GN=STMN1 PE=1 SV=3"	"0.000"	""	"14"	"2"	"4"	"2"	"149"	"17.3"	"5.97"	"697.89"	"7.05"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00836"	"3925"	"ENSG00000117632"	"STMN1"	"A2A2D1; B2R4E7; B7Z8N4; D3DPJ5; hsa:3925; P16949"	"Nuclear signaling by ERBB4"	"Microtubule cytoskeleton regulation; Retinoblastoma gene in cancer; RAC1/PAK1/p38/MMP2 pathway; MAPK signaling pathway; EGF/EGFR signaling pathway; IL-18 signaling pathway"	"7"	"0"	"406.1"	"156.0"	"287.9"	"291.4"	"356.6"	"329.2"	"287.2"	"319.8"	"233.6"	"427.7"	"676.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27797"	"Calreticulin OS=Homo sapiens OX=9606 GN=CALR PE=1 SV=1"	"0.000"	""	"8"	"3"	"5"	"3"	"417"	"48.1"	"4.44"	"810.52"	"7.04"	"3"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;extracellular matrix;plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00262"	"811"	"ENSG00000179218"	"CALR"	"hsa:811; P27797; Q6IAT4; Q9UDG2"	"Scavenging by Class A Receptors; Scavenging by Class F Receptors; ER-Phagosome pathway; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Assembly of Viral Components at the Budding Site; ATF6 (ATF6-alpha) activates chaperone genes; Calnexin/calreticulin cycle"	"Androgen receptor signaling pathway; Complement system; Photodynamic therapy-induced unfolded protein response; VEGFA-VEGFR2 signaling; GDNF signaling; Calcium regulation in cardiac cells"	"13"	"0"	"516.6"	"231.5"	"430.1"	"381.0"	"474.5"	"491.7"	"384.9"	"532.1"	"360.6"	"593.4"	"1063.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35612"	"Beta-adducin OS=Homo sapiens OX=9606 GN=ADD2 PE=1 SV=3"	"0.000"	""	"3"	"3"	"5"	"1"	"726"	"80.8"	"5.92"	"592.93"	"7.03"	"2"	"3"	"cell adhesion;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00596"	"119"	"ENSG00000075340"	"ADD2"	"A8K4P2; B4DM17; D6W5G7; D6W5G8; hsa:119; P35612; Q13482; Q16412; Q59G82; Q5U5P4; Q6P0P2; Q6PGQ4; Q7Z688; Q7Z689; Q7Z690; Q7Z691"	"Miscellaneous transport and binding events"	""	"1"	"0"	"87.6"	"40.6"	"73.5"	"79.1"	"88.0"	"89.2"	"67.4"	"106.0"	"100.6"	"224.5"	"512.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00629"	"Importin subunit alpha-3 OS=Homo sapiens OX=9606 GN=KPNA4 PE=1 SV=1"	"0.000"	""	"7"	"2"	"3"	"1"	"521"	"57.9"	"4.96"	"659.48"	"7.01"	"1"	"2"	"cell-cell signaling;other metabolic processes;transport"	"other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf01749, Pf16186"	"3840"	"ENSG00000186432"	"KPNA4"	"A8K4S6; D3DNM2; hsa:3840; O00190; O00629"	"ISG15 antiviral mechanism; NS1 Mediated Effects on Host Pathways"	"Leptin signaling pathway"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62333"	"26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1"	"0.000"	""	"8"	"2"	"4"	"2"	"389"	"44.1"	"7.49"	"805.36"	"7.01"	"2"	"2"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf16450, Pf17862"	"5706"	"ENSG00000100519"	"PSMC6"	"B2R975; hsa:5706; P49719; P62333; Q6IBU3; Q92524"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; SARS-CoV-1 targets host intracellular signalling and regulatory pathways"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"65"	"0"	"147.9"	"64.8"	"133.9"	"101.9"	"129.6"	"135.1"	"104.7"	"135.4"	"101.8"	"154.6"	"246.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14204"	"Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5"	"0.000"	""	"1"	"4"	"7"	"4"	"4646"	"532.1"	"6.40"	"1266.08"	"7.00"	"4"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03028, Pf08385, Pf08393, Pf12774, Pf12775, Pf12777, Pf12780, Pf12781, Pf17852, Pf18198, Pf18199"	"1778"	"ENSG00000197102"	"DYNC1H1"	"B0I1R0; hsa:1778; Q14204; Q6DKQ7; Q8WU28; Q92814; Q9Y4G5"	"Separation of Sister Chromatids; Neutrophil degranulation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; HCMV Early Events; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Aggrephagy; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; PAFAH1B1 copy number variation"	"23"	"0"	"95.0"	"22.7"	"57.5"	"54.3"	"54.8"	"59.1"	"53.1"	"69.9"	"62.5"	"107.6"	"212.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14444"	"Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"709"	"78.3"	"5.25"	"686.34"	"7.00"	"2"	"2"	"cell organization and biogenesis;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf12287, Pf18293"	"4076"	"ENSG00000135387"	"CAPRIN1"	"A6NMY7; D3DR06; hsa:4076; Q14444; Q15074; Q6IMN4; Q6IMN7; Q9BV09"	""	""	"0"	"0"	"59.9"	"13.2"	"42.9"	"33.4"	"43.9"	"42.9"	"30.7"	"46.9"	"42.7"	"112.4"	"311.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TAE8"	"Growth arrest and DNA damage-inducible proteins-interacting protein 1 OS=Homo sapiens OX=9606 GN=GADD45GIP1 PE=1 SV=1"	"0.000"	""	"14"	"2"	"4"	"2"	"222"	"25.4"	"10.02"	"664.32"	"6.99"	"2"	"2"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	""	"Pf10147"	"90480"	"ENSG00000179271"	"GADD45GIP1"	"hsa:90480; Q8IVM3; Q8TAE8; Q8TE51; Q969P9; Q9BSM6"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"71.8"	"27.8"	"67.0"	"67.7"	"64.3"	"76.5"	"67.8"	"96.5"	"93.8"	"227.0"	"303.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16763"	"Ubiquitin-conjugating enzyme E2 S OS=Homo sapiens OX=9606 GN=UBE2S PE=1 SV=2"	"0.000"	""	"13"	"2"	"3"	"2"	"222"	"23.8"	"8.38"	"379.42"	"6.94"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00179"	"27338"	"ENSG00000108106"	"UBE2S"	"hsa:27338; Q16763; Q9BTC1"	"Antigen processing: Ubiquitination & Proteasome degradation; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Separation of Sister Chromatids; CDK-mediated phosphorylation and removal of Cdc6; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Senescence-Associated Secretory Phenotype (SASP); Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of Cyclin B; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; Regulation of APC/C activators between G1/S and early anaphase; Phosphorylation of the APC/C; APC-Cdc20 mediated degradation of Nek2A; Transcriptional Regulation by VENTX; Aberrant regulation of mitotic exit in cancer due to RB1 defects"	""	"19"	"0"	"57.0"	"30.4"	"51.6"	"43.5"	"48.4"	"47.2"	"43.5"	"52.1"	"67.2"	"136.8"	"340.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96GQ7"	"Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2"	"0.000"	""	"6"	"4"	"7"	"4"	"796"	"89.8"	"9.28"	"1153.53"	"6.94"	"4"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271"	"55661"	""	"DDX27"	"A0AVB6; B7ZLY1; hsa:55661; Q5VXM7; Q8WYG4; Q969N7; Q96F57; Q96GQ7; Q96L97; Q9BWY9; Q9BXF0; Q9H990; Q9NWU3; Q9P0C2; Q9UGD6"	""	""	"0"	"0"	"23.6"	"9.3"	"21.4"	"20.0"	"17.6"	"19.1"	"19.3"	"16.6"	"20.7"	"29.2"	"41.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5L4"	"Mitochondrial import inner membrane translocase subunit Tim13 OS=Homo sapiens OX=9606 GN=TIMM13 PE=1 SV=1"	"0.000"	""	"12"	"1"	"4"	"1"	"95"	"10.5"	"8.18"	"619.67"	"6.93"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf02953"	"26517"	"ENSG00000099800"	"TIMM13"	"hsa:26517; P62206; Q9UHL8; Q9WTL1; Q9Y5L4"	"Mitochondrial protein import"	""	"1"	"0"	"93.9"	"40.4"	"83.6"	"69.1"	"85.5"	"100.2"	"72.9"	"95.1"	"81.0"	"208.7"	"480.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BYW2"	"Histone-lysine N-methyltransferase SETD2 OS=Homo sapiens OX=9606 GN=SETD2 PE=1 SV=3"	"0.000"	""	"1"	"2"	"4"	"2"	"2564"	"287.4"	"6.14"	"550.45"	"6.90"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00397, Pf00856, Pf08236, Pf17907"	"29072"	"ENSG00000181555"	"SETD2"	"hsa:29072; O75397; O75405; Q17RW8; Q5BKS9; Q5QGN2; Q69YI5; Q6IN64; Q6ZN53; Q6ZS25; Q8N3R0; Q8TCN0; Q9BYW2; Q9C0D1; Q9H696; Q9NZW9"	"PKMTs methylate histone lysines"	"Histone modifications; Mesodermal commitment pathway; Mesodermal commitment pathway; Pathways affected in adenoid cystic carcinoma; Clear cell renal cell carcinoma pathways; Type 2 papillary renal cell carcinoma; Pleural mesothelioma"	"8"	"0"	"119.6"	"46.7"	"101.6"	"89.5"	"98.4"	"117.1"	"88.3"	"141.4"	"127.7"	"221.4"	"405.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13283"	"Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1"	"0.000"	""	"5"	"2"	"4"	"2"	"466"	"52.1"	"5.52"	"607.21"	"6.90"	"2"	"2"	"cell organization and biogenesis;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00076, Pf02136"	"10146"	"ENSG00000145907"	"G3BP1"	"hsa:10146; Q13283; Q5HYE9"	"SARS-CoV-2 activates/modulates innate and adaptive immune responses"	""	"1"	"0"	"224.5"	"93.4"	"172.6"	"145.0"	"165.2"	"175.3"	"147.6"	"211.6"	"180.1"	"303.9"	"409.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12797"	"Aspartyl/asparaginyl beta-hydroxylase OS=Homo sapiens OX=9606 GN=ASPH PE=1 SV=3"	"0.000"	""	"5"	"3"	"6"	"3"	"758"	"85.8"	"5.01"	"825.60"	"6.90"	"3"	"3"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi"	"other molecular function"	"Pf05118, Pf05279, Pf13432"	"444"	"ENSG00000198363"	"ASPH"	"A0A0A0MSK8; A6NDF4; A6NHI2; B4DIC9; B4E2K4; B7ZM95; E5RGP5; F5H667; hsa:444; Q12797; Q6NXR7; Q8TB28; Q9H291; Q9H2C4; Q9NRI0; Q9NRI1; Q9Y4J0"	"Stimuli-sensing channels; Ion homeostasis"	""	"2"	"0"	"117.1"	"45.8"	"99.6"	"81.3"	"94.5"	"91.9"	"76.2"	"101.6"	"131.3"	"500.3"	"1204.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12872"	"Splicing factor, suppressor of white-apricot homolog OS=Homo sapiens OX=9606 GN=SFSWAP PE=1 SV=3"	"0.000"	""	"2"	"2"	"4"	"2"	"951"	"104.8"	"8.05"	"695.38"	"6.90"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf01805, Pf09750"	"6433"	"ENSG00000061936"	"SFSWAP"	"B2RN45; B7ZM97; F5H6B8; hsa:6433; Q12872; Q6PJF7"	""	"mRNA processing"	"1"	"0"	"329.5"	"102.0"	"191.7"	"178.5"	"199.9"	"238.5"	"171.5"	"252.5"	"211.5"	"404.1"	"599.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P22570"	"NADPH:adrenodoxin oxidoreductase, mitochondrial OS=Homo sapiens OX=9606 GN=FDXR PE=1 SV=3"	""	""	"9"	"2"	"2"	"2"	"491"	"53.8"	"8.44"	""	"6.89"	""	"2"	"other metabolic processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf07992"	"2232"	"ENSG00000161513"	"FDXR"	"B4DDI7; B4DHX5; B4DQQ4; B4DX24; B7Z7G2; E7EQC1; hsa:2232; P22570; Q13716; Q4PJI0; Q9BU12"	"Endogenous sterols; Pregnenolone biosynthesis; Defective CYP11A1 causes AICSR; Electron transport from NADPH to Ferredoxin"	"Iron-sulfur cluster biogenesis"	"5"	"0"	"35.0"	"12.8"	"31.2"	"16.0"	"21.4"	"27.6"	"22.6"	"31.0"	"47.6"	"122.2"	"367.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P48634"	"Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3"	"0.000"	""	"2"	"3"	"5"	"2"	"2157"	"228.7"	"9.45"	"1364.19"	"6.81"	"3"	"2"	"other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	""	"Pf07001"	"7916"	"ENSG00000204469; ENSG00000206427; ENSG00000225164; ENSG00000225748; ENSG00000226618; ENSG00000231370; ENSG00000231825"	"PRRC2A"	"B0UX77; B0UZE9; B0UZL3; hsa:7916; O95875; P48634; Q05BK4; Q4LE37; Q5SQ29; Q5SQ30; Q5ST84; Q5STX6; Q5STX7; Q68DW9; Q6P9P7; Q6PIN1; Q8MGQ9; Q96QC6"	""	""	"0"	"0"	"100.8"	"50.8"	"109.8"	"108.2"	"97.7"	"130.8"	"90.2"	"101.8"	"83.3"	"144.2"	"217.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P2K3"	"REST corepressor 3 OS=Homo sapiens OX=9606 GN=RCOR3 PE=1 SV=2"	"0.000"	""	"5"	"2"	"4"	"1"	"495"	"55.5"	"8.27"	"718.27"	"6.81"	"2"	"2"	"other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00249, Pf01448"	"55758"	"ENSG00000117625"	"RCOR3"	"B3KYA2; B4DYY7; hsa:55758; Q5VT47; Q7L9I5; Q8N5U3; Q9NV83; Q9P2K3"	""	""	"0"	"1"	"104.0"	"37.2"	"93.2"	"75.4"	"88.8"	"106.2"	"92.8"	"124.6"	"86.0"	"181.4"	"278.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13674"	"Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2"	"0.000"	""	"7"	"3"	"5"	"3"	"534"	"61.0"	"6.01"	"1003.33"	"6.80"	"3"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf08336, Pf13640"	"5033"	"ENSG00000122884"	"P4HA1"	"C9JL12; hsa:5033; P13674; Q15082; Q15083; Q5VSQ5"	"Collagen biosynthesis and modifying enzymes"	"Type I collagen synthesis in the context of osteogenesis imperfecta"	"2"	"0"	"200.8"	"92.1"	"170.9"	"123.8"	"163.9"	"180.0"	"111.8"	"194.8"	"148.3"	"294.8"	"515.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P00492"	"Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=HPRT1 PE=1 SV=2"	"0.000"	""	"13"	"2"	"4"	"2"	"218"	"24.6"	"6.68"	"843.92"	"6.80"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;developmental processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00156"	"3251"	"ENSG00000165704"	"HPRT1"	"A6NHF0; B2R8M9; hsa:3251; P00492"	"Azathioprine ADME; Purine salvage; Defective HPRT1 disrupts guanine and hypoxanthine salvage"	"Mesodermal commitment pathway"	"4"	"0"	"123.3"	"38.7"	"83.6"	"66.3"	"81.1"	"95.4"	"78.0"	"88.3"	"91.1"	"117.6"	"220.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22314"	"Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3"	"0.000"	""	"2"	"2"	"4"	"2"	"1058"	"117.8"	"5.76"	"814.14"	"6.78"	"2"	"2"	"protein metabolism;other metabolic processes;stress response"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00899, Pf09358, Pf10585, Pf16190, Pf16191"	"7317"	"ENSG00000130985"	"UBA1"	"hsa:7317; P22314; Q5JRR8; Q96E13"	"Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Antigen processing: Ubiquitination & Proteasome degradation"	"Proteasome degradation; Parkin-ubiquitin proteasomal system pathway; Parkinson's disease pathway"	"5"	"0"	"19.2"	"3.4"	"8.1"	"6.4"	"10.9"	"14.0"	"9.9"	"14.1"	"16.5"	"20.6"	"34.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5H9R7"	"Serine/threonine-protein phosphatase 6 regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PPP6R3 PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"2"	"873"	"97.6"	"4.60"	"745.57"	"6.76"	"2"	"2"	"other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	"enzyme regulator activity;other molecular function"	"Pf04499"	"55291"	"ENSG00000110075"	"PPP6R3"	"hsa:55291; Q3B7I1; Q3I4Y0; Q3KR35; Q5H9R7; Q68CR3; Q7L4R8; Q8N3B2; Q96MB2; Q9H2K5; Q9H2K6; Q9HCL4; Q9NUY3"	"Telomere Extension By Telomerase; COPII-mediated vesicle transport"	""	"2"	"0"	"103.2"	"45.1"	"91.9"	"76.0"	"91.5"	"107.9"	"64.7"	"114.2"	"99.2"	"186.7"	"429.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50607"	"Tubby protein homolog OS=Homo sapiens OX=9606 GN=TUB PE=1 SV=1"	"0.000"	""	"2"	"1"	"4"	"1"	"506"	"55.6"	"8.76"	"842.76"	"6.74"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01167, Pf16322"	"7275"	"ENSG00000166402"	"TUB"	"D3DQU4; hsa:7275; O00293; P50607; Q6B007"	""	"Ciliopathies"	"1"	"0"	"40.3"	"23.3"	"40.7"	"37.6"	"43.1"	"51.8"	"56.1"	"124.2"	"196.1"	"400.7"	"500.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30085"	"UMP-CMP kinase OS=Homo sapiens OX=9606 GN=CMPK1 PE=1 SV=3"	"0.000"	""	"6"	"1"	"4"	"1"	"196"	"22.2"	"5.57"	"682.80"	"6.72"	"1"	"1"	"other metabolic processes"	"cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00406"	"51727"	"ENSG00000162368"	"CMPK1"	"B2R6S5; B4DPU7; E9PGI8; hsa:51727; P30085; Q53GB7; Q5SVZ0; Q96C07; Q9UBQ8; Q9UIA2"	"Interconversion of nucleotide di- and triphosphates"	"Pyrimidine metabolism"	"2"	"0"	"29.3"	"10.5"	"29.3"	"25.5"	"33.7"	"36.8"	"24.6"	"27.0"	"33.9"	"53.9"	"61.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15120"	"[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial OS=Homo sapiens OX=9606 GN=PDK3 PE=1 SV=1"	"0.000"	""	"11"	"4"	"6"	"4"	"406"	"46.9"	"8.37"	"1285.76"	"6.72"	"4"	"2"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"mitochondrion;nucleus"	"kinase activity;other molecular function"	"Pf02518, Pf10436"	"5165"	"ENSG00000067992"	"PDK3"	"B4DXG6; hsa:5165; Q15120"	"Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid"	""	"2"	"0"	"233.8"	"104.2"	"213.0"	"192.9"	"199.1"	"242.8"	"184.3"	"263.2"	"262.2"	"833.8"	"1546.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00116"	"Alkyldihydroxyacetonephosphate synthase, peroxisomal OS=Homo sapiens OX=9606 GN=AGPS PE=1 SV=1"	"0.000"	""	"4"	"2"	"4"	"2"	"658"	"72.9"	"7.34"	"790.73"	"6.70"	"2"	"2"	"other metabolic processes"	"cytosol;other cytoplasmic organelle"	"other molecular function"	"Pf01565, Pf02913"	"8540"	"ENSG00000018510"	"AGPS"	"A5D8U9; hsa:8540; O00116; Q2TU35"	"Plasmalogen biosynthesis; TYSND1 cleaves peroxisomal proteins"	"Triacylglyceride synthesis"	"4"	"0"	"46.8"	"18.5"	"39.0"	"39.9"	"40.8"	"47.1"	"30.2"	"55.6"	"40.7"	"92.9"	"134.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46778"	"60S ribosomal protein L21 OS=Homo sapiens OX=9606 GN=RPL21 PE=1 SV=2"	"0.000"	""	"23"	"4"	"6"	"4"	"160"	"18.6"	"10.49"	"1324.40"	"6.69"	"4"	"2"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;other cell component"	"other molecular function"	"Pf01157"	"6144"	"ENSG00000122026"	"RPL21"	"hsa:6144; P46778; Q16699"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"1202.2"	"473.5"	"1057.2"	"882.6"	"969.8"	"1182.7"	"794.7"	"1084.8"	"765.5"	"1350.0"	"1791.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IUH3"	"RNA-binding protein 45 OS=Homo sapiens OX=9606 GN=RBM45 PE=1 SV=1"	"0.000"	""	"3"	"2"	"6"	"2"	"476"	"53.5"	"7.17"	"828.85"	"6.68"	"2"	"2"	"developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"129831"	"ENSG00000155636"	"RBM45"	"hsa:129831; Q6NYL0; Q8IUH3; Q8NFC9"	""	""	"0"	"0"	"555.0"	"237.7"	"517.1"	"437.1"	"446.6"	"564.3"	"389.4"	"492.2"	"405.5"	"658.4"	"898.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HB21"	"Pleckstrin homology domain-containing family A member 1 OS=Homo sapiens OX=9606 GN=PLEKHA1 PE=1 SV=2"	"0.000"	""	"5"	"2"	"4"	"2"	"404"	"45.5"	"8.56"	"738.95"	"6.68"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00169"	"59338"	"ENSG00000107679"	"PLEKHA1"	"B3KQ55; D3DRE2; hsa:59338; Q9BVK0; Q9HB21"	"Synthesis of PIPs at the plasma membrane"	""	"1"	"0"	"37.2"	"19.0"	"29.9"	"18.3"	"26.7"	"32.1"	"38.9"	"105.0"	"189.2"	"690.7"	"1042.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96J02"	"E3 ubiquitin-protein ligase Itchy homolog OS=Homo sapiens OX=9606 GN=ITCH PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"903"	"102.7"	"6.30"	"326.24"	"6.68"	"1"	"2"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00168, Pf00397, Pf00632"	"83737"	"ENSG00000078747"	"ITCH"	"A6NEW4; B4E234; E1P5P3; F5H217; hsa:83737; O43584; Q5QP37; Q5TEL0; Q96F66; Q96J02; Q9BY75; Q9H451; Q9H4U5"	"Antigen processing: Ubiquitination & Proteasome degradation; Degradation of GLI1 by the proteasome; Hedgehog 'on' state; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Activated NOTCH1 Transmits Signal to the Nucleus; Regulation of necroptotic cell death; NOD1/2 Signaling Pathway; Negative regulators of DDX58/IFIH1 signaling; SARS-CoV-1 activates/modulates innate immune responses; Downregulation of ERBB4 signaling"	"VEGFA-VEGFR2 signaling; EGF/EGFR signaling pathway; Nonalcoholic fatty liver disease; 10q11.21q11.23 copy number variation syndrome; Notch signaling pathway"	"15"	"0"	"78.0"	"35.2"	"68.4"	"59.1"	"71.5"	"86.9"	"66.4"	"100.7"	"80.4"	"197.2"	"438.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NW64"	"Pre-mRNA-splicing factor RBM22 OS=Homo sapiens OX=9606 GN=RBM22 PE=1 SV=1"	"0.000"	""	"5"	"2"	"4"	"2"	"420"	"46.9"	"8.54"	"835.52"	"6.67"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"55696"	"ENSG00000086589"	"RBM22"	"A6NDM5; B4DLI9; hsa:55696; O95607; Q9NW64"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"689.1"	"193.7"	"518.2"	"384.9"	"461.2"	"520.9"	"370.8"	"499.6"	"361.9"	"732.7"	"1219.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P43034"	"Platelet-activating factor acetylhydrolase IB subunit alpha OS=Homo sapiens OX=9606 GN=PAFAH1B1 PE=1 SV=2"	"0.001"	""	"7"	"2"	"3"	"2"	"410"	"46.6"	"7.37"	"290.79"	"6.66"	"1"	"2"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf08513"	"5048"	"ENSG00000007168"	"PAFAH1B1"	"B2R7Q7; hsa:5048; P43034; Q8WZ88; Q8WZ89"	"Resolution of Sister Chromatid Cohesion; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Separation of Sister Chromatids; RHO GTPases Activate Formins; COPI-independent Golgi-to-ER retrograde traffic; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"Wnt signaling pathway and pluripotency; Ciliary landscape; Neurogenesis regulation in the olfactory epithelium; PAFAH1B1 copy number variation"	"18"	"0"	"171.0"	"79.4"	"148.4"	"127.4"	"154.6"	"187.4"	"134.4"	"175.9"	"153.7"	"300.9"	"449.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62993"	"Growth factor receptor-bound protein 2 OS=Homo sapiens OX=9606 GN=GRB2 PE=1 SV=1"	"0.000"	""	"10"	"2"	"4"	"2"	"217"	"25.2"	"6.32"	"717.70"	"6.65"	"2"	"2"	"cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00017, Pf00018"	"2885"	"ENSG00000177885"	"GRB2"	"hsa:2885; P29354; P62993; Q14450; Q63057; Q63059"	"Signaling by ALK fusions and activated point mutants; Signaling by CSF3 (G-CSF); STAT5 activation downstream of FLT3 ITD mutants; Interleukin-15 signaling"	"IL-5 signaling pathway; Integrin-mediated cell adhesion; Leptin signaling pathway; Prolactin signaling pathway; IL-9 signaling pathway; Pilocytic astrocytoma; Glioblastoma signaling pathways; Androgen receptor network in prostate cancer; B cell receptor signaling pathway; TNF-alpha signaling pathway; Interleukin-11 signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Alpha 6 beta 4 signaling pathway; IL-3 signaling pathway; Kit receptor signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; RAC1/PAK1/p38/MMP2 pathway; IL6 signaling pathway; Hepatitis C and hepatocellular carcinoma; BDNF-TrkB signaling; Physico-chemical features and toxicity-associated pathways; MAPK signaling pathway; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Embryonic stem cell pluripotency pathways; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; IL-4 signaling pathway; p38 MAPK signaling pathway; Endometrial cancer; PI3K-Akt signaling pathway; MAPK cascade; Ras signaling; Epithelial to mesenchymal transition in colorectal cancer; Breast cancer pathway; Thermogenesis; EGF/EGFR signaling pathway; Envelope proteins and their potential roles in EDMD physiopathology; Fragile X syndrome; Gastrin signaling pathway; Hepatitis B infection; Melanoma; Thyroid hormones production and peripheral downstream signaling effects; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; IL-2 signaling pathway; 7q11.23 copy number variation syndrome; 16p11.2 distal deletion syndrome; Modulators of TCR signaling and T cell activation; Kallmann syndrome; Pleural mesothelioma; Congenital generalized lipodystrophy; GDNF signaling; 2q13 copy number variation syndrome; A network map of Macrophage-stimulating protein (MSP) signaling; 4p16.3 copy number variation; 5q35 copy number variation; EPO receptor signaling; ErbB signaling pathway; T-cell receptor signaling pathway; DNA damage response (only ATM dependent)"	"68"	"0"	"330.0"	"166.7"	"317.6"	"294.5"	"319.8"	"342.2"	"257.0"	"346.0"	"288.0"	"538.2"	"935.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H5V9"	"UPF0428 protein CXorf56 OS=Homo sapiens OX=9606 GN=CXorf56 PE=1 SV=1"	"0.000"	""	"14"	"3"	"4"	"3"	"222"	"25.6"	"8.73"	"526.94"	"6.65"	"2"	"2"	"cell organization and biogenesis;transport"	"cytoskeleton;nucleus;other cell component"	""	""	"63932"	"ENSG00000018610"	"STEEP1"	"A8MPX7; B4DQN2; D3DWH9; F5GWL7; hsa:63932; O43351; Q9H5V9"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"268.1"	"106.0"	"231.8"	"197.9"	"218.6"	"258.9"	"195.6"	"278.4"	"217.8"	"441.8"	"729.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N3R9"	"MAGUK p55 subfamily member 5 OS=Homo sapiens OX=9606 GN=MPP5 PE=1 SV=3"	"0.000"	""	"6"	"3"	"5"	"3"	"675"	"77.2"	"6.14"	"1107.03"	"6.64"	"3"	"2"	"cell organization and biogenesis;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf00595, Pf00625, Pf02828, Pf07653, Pf09060"	"64398"	"ENSG00000072415"	"PALS1"	"A1L380; hsa:64398; Q7Z631; Q86T98; Q8N3R9; Q8N7I5; Q9H9Q0"	"Tight junction interactions; SARS-CoV-2 targets PDZ proteins in cell-cell junction; SARS-CoV-1 targets PDZ proteins in cell-cell junction"	"Epithelial to mesenchymal transition in colorectal cancer; Complement system in neuronal development and plasticity"	"5"	"0"	"166.7"	"67.6"	"138.6"	"114.2"	"128.0"	"154.1"	"99.9"	"137.6"	"111.9"	"161.5"	"245.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H4L7"	"SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 OS=Homo sapiens OX=9606 GN=SMARCAD1 PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"2"	"1026"	"117.3"	"5.55"	"816.63"	"6.64"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271"	"56916"	"ENSG00000163104"	"SMARCAD1"	"B7Z799; hsa:56916; Q05D56; Q96SX1; Q9H017; Q9H4L7; Q9H860; Q9NPU9; Q9ULU7"	""	""	"0"	"0"	"214.3"	"109.7"	"236.3"	"220.9"	"211.5"	"250.8"	"216.7"	"308.1"	"208.5"	"314.5"	"444.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBN7"	"Histone deacetylase 6 OS=Homo sapiens OX=9606 GN=HDAC6 PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"2"	"1215"	"131.3"	"5.30"	"667.41"	"6.62"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00850, Pf02148"	"10013"	"ENSG00000094631"	"HDAC6"	"hsa:10013; O94975; Q6NT75; Q7L3E5; Q96CY0; Q9UBN7"	"Late endosomal microautophagy; Cilium Assembly; Aggrephagy; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Transcriptional regulation by RUNX2; NOTCH1 Intracellular Domain Regulates Transcription; Notch-HLH transcription pathway; RUNX2 regulates osteoblast differentiation; Chaperone Mediated Autophagy; HSF1 activation"	"Neural crest differentiation; Ectoderm differentiation; Ectoderm differentiation; Ethanol effects on histone modifications; 7q11.23 copy number variation syndrome"	"16"	"0"	"207.5"	"170.7"	"236.0"	"223.3"	"218.1"	"254.5"	"170.4"	"221.7"	"225.2"	"502.4"	"951.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96P47"	"Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 OS=Homo sapiens OX=9606 GN=AGAP3 PE=1 SV=2"	"0.000"	""	"3"	"3"	"5"	"2"	"875"	"95.0"	"7.97"	"1042.30"	"6.61"	"3"	"2"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00071, Pf01412, Pf12796"	"116988"	"ENSG00000133612"	"AGAP3"	"B3KNZ8; E9PAL8; hsa:116988; Q59EN0; Q96P47; Q96RK3"	""	""	"0"	"1"	"105.9"	"63.5"	"121.1"	"95.4"	"146.5"	"164.2"	"209.7"	"436.9"	"654.6"	"1840.6"	"2380.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BZI7"	"Regulator of nonsense transcripts 3B OS=Homo sapiens OX=9606 GN=UPF3B PE=1 SV=1"	"0.000"	""	"4"	"2"	"3"	"2"	"483"	"57.7"	"9.48"	"440.78"	"6.60"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity"	"Pf03467"	"65109"	"ENSG00000125351"	"UPF3B"	"D3DWI3; D3DWI4; hsa:65109; Q0VAK8; Q9BZI7; Q9H1J0"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); mRNA Splicing - Major Pathway; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing"	""	"6"	"0"	"239.7"	"85.0"	"186.9"	"187.2"	"190.5"	"227.7"	"141.8"	"226.2"	"184.5"	"483.7"	"1232.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00505"	"Importin subunit alpha-4 OS=Homo sapiens OX=9606 GN=KPNA3 PE=1 SV=2"	"0.000"	""	"5"	"2"	"4"	"1"	"521"	"57.8"	"4.94"	"1059.35"	"6.59"	"2"	"2"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf01749, Pf16186"	"3839"	"ENSG00000102753"	"KPNA3"	"hsa:3839; O00191; O00505; O43195; Q5JVM9; Q8IYQ9; Q96AA7"	"ISG15 antiviral mechanism; NS1 Mediated Effects on Host Pathways"	""	"2"	"1"	"163.6"	"71.5"	"177.8"	"199.4"	"155.0"	"254.5"	"159.1"	"166.3"	"115.9"	"211.0"	"360.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y2D4"	"Exocyst complex component 6B OS=Homo sapiens OX=9606 GN=EXOC6B PE=1 SV=3"	""	""	"3"	"2"	"2"	"2"	"811"	"94.1"	"6.46"	""	"6.58"	""	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport"	"other cell component"	""	"Pf04091"	"23233"	"ENSG00000144036"	"EXOC6B"	"B8ZZY3; hsa:23233; Q9Y2D4"	""	"Ciliary landscape"	"1"	"0"	"6.7"	"4.1"	"7.0"	"5.6"	"4.1"	"7.7"	"9.8"	"18.1"	"16.7"	"71.7"	"152.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q0VDF9"	"Heat shock 70 kDa protein 14 OS=Homo sapiens OX=9606 GN=HSPA14 PE=1 SV=1"	"0.000"	""	"3"	"1"	"4"	"1"	"509"	"54.8"	"5.59"	"741.19"	"6.58"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00012"	"51182"	"ENSG00000187522"	"HSPA14"	"A8K8F8; B0YIY9; hsa:51182; Q0VDF9; Q9P0X2; Q9UI07"	"Regulation of HSF1-mediated heat shock response"	"Parkin-ubiquitin proteasomal system pathway"	"2"	"0"	"12.6"	"5.7"	"6.5"	"5.6"	"7.4"	"5.9"	"12.3"	"11.6"	"12.1"	"101.7"	"335.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5JWF2"	"Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas OS=Homo sapiens OX=9606 GN=GNAS PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"1"	"1037"	"111.0"	"5.03"	"606.82"	"6.57"	"2"	"2"	"cell adhesion;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00503"	"2778"	"ENSG00000087460"	"GNAS"	"A2A2S3; E1P5G3; O75684; O75685; Q5JW67; Q5JWF1; Q5JWF2; Q9NY42"	"G alpha (i) signalling events; G alpha (z) signalling events; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Prostacyclin signalling through prostacyclin receptor; Glucagon-type ligand receptors; Vasopressin regulates renal water homeostasis via Aquaporins; PKA activation in glucagon signalling; Hedgehog 'off' state"	"Thyroid stimulating hormone (TSH) signaling pathway; Endothelin pathways; Corticotropin-releasing hormone signaling pathway; Common pathways underlying drug addiction; Myometrial relaxation and contraction pathways; G protein signaling pathways; Thermogenesis; Hippo signaling regulation pathways; Purinergic signaling; GPR143 in melanocytes and retinal pigment epithelium cells; Prostaglandin and leukotriene metabolism in senescence ; Primary ovarian insufficiency; Prostaglandin and leukotriene metabolism in senescence ; Calcium regulation in cardiac cells; Estrogen signaling pathway; Serotonin receptor 4/6/7 and NR3C signaling"	"28"	"0"	"32.4"	"14.2"	"21.8"	"23.6"	"29.5"	"25.6"	"25.2"	"37.2"	"32.2"	"63.3"	"152.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12899"	"Tripartite motif-containing protein 26 OS=Homo sapiens OX=9606 GN=TRIM26 PE=1 SV=1"	"0.000"	""	"5"	"2"	"4"	"2"	"539"	"62.1"	"5.03"	"753.30"	"6.54"	"2"	"2"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00622, Pf00643, Pf13765, Pf15227"	"7726"	"ENSG00000137313; ENSG00000226060; ENSG00000228881; ENSG00000230230; ENSG00000231002; ENSG00000231641; ENSG00000234046; ENSG00000234127"	"TRIM26"	"A6NG96; hsa:7726; Q12899; Q5SRL2"	"Interferon gamma signaling"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00257"	"E3 SUMO-protein ligase CBX4 OS=Homo sapiens OX=9606 GN=CBX4 PE=1 SV=3"	"0.000"	""	"5"	"2"	"3"	"2"	"560"	"61.3"	"9.36"	"406.38"	"6.53"	"1"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00385, Pf17218"	"8535"	"ENSG00000141582"	"CBX4"	"B1PJR7; hsa:8535; O00257; Q6TPI8; Q96C04"	"SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Oxidative Stress Induced Senescence; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Regulation of PTEN gene transcription"	""	"8"	"0"	"136.4"	"47.7"	"101.9"	"108.8"	"122.1"	"133.9"	"83.4"	"138.1"	"99.0"	"219.3"	"418.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P60002"	"Transcription elongation factor 1 homolog OS=Homo sapiens OX=9606 GN=ELOF1 PE=1 SV=1"	""	""	"22"	"1"	"1"	"1"	"83"	"9.5"	"8.00"	""	"6.52"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf05129"	"84337"	"ENSG00000130165"	"ELOF1"	"hsa:84337; P60002; Q8R1J7; Q96II4"	""	""	"0"	"0"	"19.4"	"7.7"	"20.6"	"17.5"	"21.7"	"19.3"	"12.1"	"28.4"	"35.2"	"333.4"	"616.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P54727"	"UV excision repair protein RAD23 homolog B OS=Homo sapiens OX=9606 GN=RAD23B PE=1 SV=1"	"0.000"	""	"6"	"3"	"5"	"3"	"409"	"43.1"	"4.84"	"997.36"	"6.52"	"3"	"2"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00240, Pf00627, Pf09280"	"5887"	"ENSG00000119318"	"RAD23B"	"B3KWK8; G5E9P0; hsa:5887; P54727; Q7Z5K8; Q8WUB0"	"Formation of Incision Complex in GG-NER; Josephin domain DUBs; DNA Damage Recognition in GG-NER; N-glycan trimming in the ER and Calnexin/Calreticulin cycle"	"Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"7"	"0"	"797.5"	"416.5"	"704.4"	"609.0"	"763.1"	"791.1"	"639.1"	"772.7"	"626.9"	"1099.4"	"1967.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8ND56"	"Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3"	"0.000"	""	"7"	"3"	"5"	"2"	"463"	"50.5"	"9.52"	"891.18"	"6.52"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;signal transduction;other biological processes"	"cytosol;cytoskeleton;other cell component"	"nucleic acid binding activity"	"Pf09532, Pf12701"	"26065"	"ENSG00000257103; ENSG00000262860"	"LSM14A"	"B4DTG6; hsa:26065; Q76LX7; Q8ND56; Q96AR3; Q96K73; Q96SN5; Q9UFR3"	""	""	"0"	"0"	"237.0"	"91.0"	"206.5"	"227.8"	"220.7"	"237.8"	"163.9"	"223.9"	"145.9"	"312.9"	"782.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q69YN2"	"CWF19-like protein 1 OS=Homo sapiens OX=9606 GN=CWF19L1 PE=1 SV=2"	""	""	"5"	"2"	"2"	"2"	"538"	"60.6"	"7.24"	""	"6.52"	""	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"enzyme regulator activity"	"Pf04676, Pf04677"	"55280"	"ENSG00000095485"	"CWF19L1"	"B4DHX1; D3DR66; hsa:55280; Q5W0I3; Q69YN2; Q96HC3; Q9H865; Q9NV13"	""	""	"0"	"0"	"77.1"	"31.3"	"66.0"	"55.1"	"66.6"	"73.1"	"60.0"	"80.2"	"79.4"	"128.4"	"371.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8NBT2"	"Kinetochore protein Spc24 OS=Homo sapiens OX=9606 GN=SPC24 PE=1 SV=2"	""	""	"14"	"1"	"1"	"1"	"197"	"22.5"	"4.70"	""	"6.49"	""	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"8.7"	"4.0"	"13.4"	"9.8"	"12.4"	"12.2"	"9.4"	"13.6"	"12.0"	"25.6"	"33.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BTT0"	"Acidic leucine-rich nuclear phosphoprotein 32 family member E OS=Homo sapiens OX=9606 GN=ANP32E PE=1 SV=1"	"0.000"	""	"11"	"2"	"4"	"2"	"268"	"30.7"	"3.85"	"823.56"	"6.49"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf14580"	"81611"	"ENSG00000143401"	"ANP32E"	"B4E0I6; E9PEA6; hsa:81611; Q5TB18; Q5TB20; Q8N1S4; Q8WWW9; Q9BTT0"	""	""	"0"	"0"	"188.2"	"82.6"	"177.0"	"164.9"	"181.5"	"238.1"	"190.2"	"212.8"	"159.7"	"245.0"	"361.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00541"	"Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1"	"0.000"	""	"4"	"2"	"4"	"2"	"588"	"68.0"	"7.33"	"704.10"	"6.48"	"2"	"2"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf06732, Pf16589"	"23481"	"ENSG00000100029"	"PES1"	"hsa:23481; O00541; Q6IC29"	"Major pathway of rRNA processing in the nucleolus and cytosol"	""	"1"	"0"	"56.9"	"23.3"	"50.9"	"44.2"	"48.1"	"54.3"	"45.6"	"58.4"	"52.1"	"118.6"	"334.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15022"	"Polycomb protein SUZ12 OS=Homo sapiens OX=9606 GN=SUZ12 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"739"	"83.0"	"8.81"	"511.69"	"6.48"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf09733"	"23512"	"ENSG00000178691"	"SUZ12"	"hsa:23512; Q15022; Q96BD9"	"HCMV Early Events; Oxidative Stress Induced Senescence; Activation of anterior HOX genes in hindbrain development during early embryogenesis; PRC2 methylates histones and DNA; Defective pyroptosis; SUMOylation of chromatin organization proteins; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6; PKMTs methylate histone lysines"	"Interactome of polycomb repressive complex 2 (PRC2) ; Tumor suppressor activity of SMARCB1; Epithelial to mesenchymal transition in colorectal cancer; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; Pleural mesothelioma"	"14"	"0"	"14.2"	"4.6"	"17.7"	"8.6"	"16.9"	"16.6"	"14.0"	"15.4"	"14.7"	"31.1"	"58.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H3U1"	"Protein unc-45 homolog A OS=Homo sapiens OX=9606 GN=UNC45A PE=1 SV=1"	"0.000"	""	"4"	"2"	"3"	"2"	"944"	"103.0"	"6.07"	"371.93"	"6.46"	"1"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf11701, Pf13181, Pf13432"	"55898"	"ENSG00000140553"	"UNC45A"	"A8K6F7; hsa:55898; Q7L3Y6; Q9H3U1; Q9H3U8; Q9NSE8; Q9NSE9"	""	""	"0"	"0"	"16.5"	"6.0"	"9.5"	"15.7"	"17.0"	"13.8"	"9.8"	"19.6"	"15.9"	"28.5"	"67.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q4G0J3"	"La-related protein 7 OS=Homo sapiens OX=9606 GN=LARP7 PE=1 SV=1"	"0.000"	""	"5"	"3"	"5"	"3"	"582"	"66.9"	"9.55"	"1251.30"	"6.46"	"3"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf05383, Pf08777"	"51574"	"ENSG00000174720"	"LARP7"	"B2ZHN6; hsa:51574; Q3B7A9; Q4G0J3; Q9P1S7; Q9Y3Z8"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"181.7"	"66.8"	"155.8"	"141.1"	"153.5"	"180.5"	"123.6"	"176.3"	"128.4"	"256.2"	"413.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2S7"	"Polymerase delta-interacting protein 2 OS=Homo sapiens OX=9606 GN=POLDIP2 PE=1 SV=1"	"0.000"	""	"6"	"2"	"4"	"2"	"368"	"42.0"	"8.63"	"701.10"	"6.40"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytoskeleton;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity"	"Pf04379, Pf08755"	"26073"	"ENSG00000004142"	"POLDIP2"	"B2R846; hsa:26073; Q96JE4; Q9Y2S7"	""	""	"0"	"0"	"138.7"	"65.7"	"144.6"	"121.4"	"119.4"	"149.1"	"123.9"	"153.8"	"114.6"	"236.2"	"402.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35222"	"Catenin beta-1 OS=Homo sapiens OX=9606 GN=CTNNB1 PE=1 SV=1"	"0.000"	""	"3"	"3"	"5"	"2"	"781"	"85.4"	"5.86"	"949.03"	"6.38"	"3"	"2"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00514"	"1499"	"ENSG00000168036"	"CTNNB1"	"A8K1L7; hsa:1499; P35222; Q8NEW9; Q8NI94; Q9H391"	"Somitogenesis; Deactivation of the beta-catenin transactivating complex; InlA-mediated entry of Listeria monocytogenes into host cells; Ca2+ pathway; RHO GTPases activate IQGAPs; Formation of paraxial mesoderm; Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1); Formation of axial mesoderm; Myogenesis; Transcriptional Regulation by VENTX; Disassembly of the destruction complex and recruitment of AXIN to the membrane; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; Cardiogenesis; Germ layer formation at gastrulation; Formation of definitive endoderm; VEGFR2 mediated vascular permeability; Adherens junctions interactions; Regulation of CDH11 function; Regulation of CDH19 Expression and Function; CDH11 homotypic and heterotypic interactions; Binding of TCF/LEF:CTNNB1 to target gene promoters; RUNX3 regulates WNT signaling; Apoptotic cleavage of cell adhesion  proteins; LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production"	"Androgen receptor signaling pathway; MicroRNAs in cardiomyocyte hypertrophy; Heart development; TNF-related weak inducer of apoptosis (TWEAK) signaling pathway; Alzheimer's disease and miRNA effects; Neural crest differentiation; Arrhythmogenic right ventricular cardiomyopathy; Pathogenic Escherichia coli infection; Corticotropin-releasing hormone signaling pathway; Adipogenesis; Gastric cancer network 2; Brain-derived neurotrophic factor (BDNF) signaling pathway; Primary focal segmental glomerulosclerosis (FSGS); Endoderm differentiation; Ectoderm differentiation; Extracellular vesicle-mediated signaling in recipient cells; Focal adhesion; Ectoderm differentiation; RAC1/PAK1/p38/MMP2 pathway; Wnt signaling pathway; Regulation of Wnt / B-catenin signaling by small molecule compounds; Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Embryonic stem cell pluripotency pathways; H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity; OSX and miRNAs in tooth development; Wnt signaling pathway and pluripotency; PTF1A related regulatory pathway; Wnt signaling in kidney disease; Endometrial cancer; Chromosomal and microsatellite instability in colorectal cancer ; Epithelial to mesenchymal transition in colorectal cancer; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Ciliary landscape; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; Gastrin signaling pathway; Head and neck squamous cell carcinoma; Thyroid hormones production and peripheral downstream signaling effects; IL-18 signaling pathway; Osteoblast differentiation and related diseases; TGF-beta receptor signaling in skeletal dysplasias; Genes controlling nephrogenesis; GDNF/RET signaling axis; Mammalian disorder of sexual development; Influence of laminopathies on Wnt signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies; 1q21.1 copy number variation syndrome; 7q11.23 copy number variation syndrome; Development of ureteric collection system; Pleural mesothelioma; Alzheimer's disease; Urotensin-II-mediated signaling pathway; Markers of kidney cell lineage; TROP2 regulatory signaling; 8p23.1 copy number variation syndrome; A network map of Macrophage-stimulating protein (MSP) signaling; TGF-beta receptor signaling; Sudden infant death syndrome (SIDS) susceptibility pathways; DNA damage response (only ATM dependent)"	"96"	"0"	"64.0"	"22.2"	"45.5"	"43.9"	"53.8"	"53.3"	"58.1"	"55.3"	"45.8"	"95.9"	"199.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P55145"	"Mesencephalic astrocyte-derived neurotrophic factor OS=Homo sapiens OX=9606 GN=MANF PE=1 SV=3"	""	""	"10"	"2"	"2"	"2"	"182"	"20.7"	"8.69"	""	"6.35"	""	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf10208, Pf20145"	"7873"	"ENSG00000145050"	"MANF"	"hsa:7873; P55145; Q14CX4; Q86U67; Q96IS4"	"Platelet degranulation"	"Orexin receptor pathway"	"2"	"0"	"132.0"	"48.1"	"92.5"	"85.7"	"99.1"	"121.4"	"117.4"	"138.6"	"155.1"	"1064.5"	"1917.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82664"	"28S ribosomal protein S10, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS10 PE=1 SV=2"	"0.000"	""	"13"	"2"	"4"	"2"	"201"	"23.0"	"8.00"	"699.74"	"6.33"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	""	"Pf00338"	"55173"	"ENSG00000048544"	"MRPS10"	"B2RE89; hsa:55173; P82664; Q9H3E5; Q9NVR3"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"53.3"	"22.7"	"33.6"	"28.7"	"39.1"	"50.1"	"31.9"	"47.6"	"45.6"	"66.9"	"111.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92620"	"Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 OS=Homo sapiens OX=9606 GN=DHX38 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"1227"	"140.4"	"6.54"	"667.16"	"6.33"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"9785"	"ENSG00000140829"	"DHX38"	"B4DVG8; D3DWS7; hsa:9785; O75212; Q92620; Q96HN7"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA Splicing - Major Pathway; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"mRNA processing"	"5"	"0"	"17.5"	"8.1"	"8.9"	"8.9"	"12.1"	"13.3"	"10.1"	"14.3"	"16.8"	"21.2"	"44.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61962"	"DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1"	"0.000"	""	"6"	"2"	"4"	"2"	"342"	"38.9"	"5.52"	"593.09"	"6.33"	"2"	"2"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00400"	"10238"	"ENSG00000136485"	"DCAF7"	"B4E039; D3DU14; hsa:10238; O15491; P61962; Q9DAE4"	"Neddylation; Association of TriC/CCT with target proteins during biosynthesis"	"Ciliary landscape; DYRK1A involvement regarding cell proliferation in brain development"	"4"	"0"	"80.7"	"42.3"	"89.2"	"88.7"	"98.3"	"106.4"	"69.2"	"96.5"	"76.8"	"148.0"	"247.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09038"	"Fibroblast growth factor 2 OS=Homo sapiens OX=9606 GN=FGF2 PE=1 SV=3"	"0.000"	""	"7"	"2"	"4"	"2"	"288"	"30.8"	"11.18"	"703.16"	"6.31"	"2"	"2"	"cell-cell signaling;cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00167"	"2247"	"ENSG00000138685"	"FGF2"	"A4LBB8; hsa:2247; O00527; P09038; P78443; Q16443; Q5PY50; Q7KZ11; Q7KZ72; Q9UC54; Q9UCS5; Q9UCS6"	"PIP3 activates AKT signaling; Constitutive Signaling by Aberrant PI3K in Cancer; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; RAF/MAP kinase cascade; PI3K Cascade; Interleukin-4 and Interleukin-13 signaling; Syndecan interactions; Signaling by FGFR1 in disease; Signaling by FGFR2 IIIa TM; FGFR1b ligand binding and activation; FGFR2b ligand binding and activation; Activated point mutants of FGFR2; Phospholipase C-mediated cascade: FGFR1; Phospholipase C-mediated cascade; FGFR2; SHC-mediated cascade:FGFR1; PI-3K cascade:FGFR1; FRS-mediated FGFR1 signaling; PI-3K cascade:FGFR2; SHC-mediated cascade:FGFR2; FRS-mediated FGFR2 signaling; Negative regulation of FGFR1 signaling; Negative regulation of FGFR2 signaling; Signaling by FGFR2 in disease; FGFRL1 modulation of FGFR1 signaling; Signaling by activated point mutants of FGFR3; FGFR4 ligand binding and activation; FGFR3c ligand binding and activation; FGFR2c ligand binding and activation; Phospholipase C-mediated cascade; FGFR3; Phospholipase C-mediated cascade; FGFR4; SHC-mediated cascade:FGFR3; FRS-mediated FGFR3 signaling; PI-3K cascade:FGFR3; FRS-mediated FGFR4 signaling; SHC-mediated cascade:FGFR4; PI-3K cascade:FGFR4; Negative regulation of FGFR3 signaling; Negative regulation of FGFR4 signaling; Signaling by FGFR3 in disease; Signaling by activated point mutants of FGFR1; FGFR1c ligand binding and activation; POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation; Formation of intermediate mesoderm"	"Angiogenesis; MicroRNAs in cardiomyocyte hypertrophy; Neural crest differentiation; Cardiac progenitor differentiation; Cardiac hypertrophic response; Pluripotent stem cell differentiation pathway; MECP2 and associated Rett syndrome; Lung fibrosis; MAPK signaling pathway; Embryonic stem cell pluripotency pathways; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Endometrial cancer; PI3K-Akt signaling pathway; Breast cancer pathway; Endochondral ossification; Osteoblast differentiation and related diseases; EGFR tyrosine kinase inhibitor resistance; Endochondral ossification with skeletal dysplasias; Neuroinflammation and glutamatergic signaling; Pleural mesothelioma; CCL18 signaling pathway; Regulation of actin cytoskeleton; DYRK1A involvement regarding cell proliferation in brain development; 4p16.3 copy number variation"	"69"	"0"	"118.2"	"71.1"	"114.9"	"96.9"	"98.5"	"120.9"	"96.0"	"143.3"	"223.1"	"826.7"	"629.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15014"	"Mortality factor 4-like protein 2 OS=Homo sapiens OX=9606 GN=MORF4L2 PE=1 SV=1"	"0.000"	""	"9"	"2"	"4"	"2"	"288"	"32.3"	"9.72"	"750.72"	"6.30"	"2"	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	""	"Pf05712"	"9643"	"ENSG00000123562"	"MORF4L2"	"B3KP92; D3DXA5; hsa:9643; Q15014; Q567V0; Q8J026"	"HATs acetylate histones"	""	"1"	"0"	"89.7"	"51.5"	"101.1"	"75.4"	"100.3"	"101.7"	"63.4"	"104.1"	"82.9"	"256.7"	"530.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NYR9"	"NF-kappa-B inhibitor-interacting Ras-like protein 2 OS=Homo sapiens OX=9606 GN=NKIRAS2 PE=1 SV=1"	"0.000"	""	"6"	"1"	"3"	"1"	"191"	"21.5"	"8.05"	"340.65"	"6.29"	"1"	"1"	"stress response;developmental processes;signal transduction;other biological processes"	"other cell component"	"other molecular function"	"Pf00071"	"28511"	"ENSG00000168256"	"NKIRAS2"	"A6NCZ5; B3KNN0; B4DNM3; hsa:28511; Q6PK52; Q96KC7; Q9NSX1; Q9NYR9"	"RIP-mediated NFkB activation via ZBP1; TAK1-dependent IKK and NF-kappa-B activation  ; TRAF6 mediated NF-kB activation"	""	"3"	"0"	"38.6"	"18.8"	"34.6"	"29.8"	"36.6"	"32.6"	"39.4"	"56.4"	"61.3"	"142.1"	"259.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKY7"	"Protein CDV3 homolog OS=Homo sapiens OX=9606 GN=CDV3 PE=1 SV=1"	"0.000"	""	"6"	"2"	"4"	"2"	"258"	"27.3"	"6.40"	"563.13"	"6.28"	"2"	"2"	""	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf15359"	"55573"	"ENSG00000091527"	"CDV3"	"B3KUC2; hsa:55573; Q96IP9; Q9UKY7"	""	""	"0"	"0"	"288.2"	"156.7"	"214.3"	"242.0"	"235.2"	"262.7"	"248.2"	"291.1"	"284.6"	"631.2"	"1638.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBP9"	"PTB domain-containing engulfment adapter protein 1 OS=Homo sapiens OX=9606 GN=GULP1 PE=1 SV=1"	"0.000"	""	"7"	"2"	"4"	"2"	"304"	"34.5"	"7.90"	"703.27"	"6.27"	"2"	"2"	"cell organization and biogenesis;transport;other biological processes"	"other cell component"	""	"Pf00640"	"51454"	"ENSG00000144366"	"GULP1"	"B2RB51; B4DQ40; B8ZZ72; D3DPH1; E9PB86; hsa:51454; Q53PC1; Q53RF3; Q9BVL3; Q9UBP9"	""	""	"0"	"0"	"67.3"	"23.3"	"63.5"	"52.0"	"61.1"	"63.7"	"48.8"	"155.5"	"305.7"	"823.5"	"784.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26640"	"Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS1 PE=1 SV=4"	"0.000"	""	"2"	"2"	"4"	"2"	"1264"	"140.4"	"7.59"	"776.00"	"6.25"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol"	"other molecular function"	"Pf00043, Pf00133, Pf08264"	"7407"	"ENSG00000096171; ENSG00000204394; ENSG00000224264; ENSG00000226589; ENSG00000231116"	"VARS1"	"B0V1N1; B4DZ61; hsa:7407; P26640; Q5JQ90; Q96E77; Q9UQM2"	"Cytosolic tRNA aminoacylation"	"Amino acid metabolism"	"2"	"0"	"188.2"	"76.1"	"159.8"	"147.9"	"149.3"	"192.4"	"154.5"	"195.8"	"167.2"	"311.2"	"572.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12788"	"Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"808"	"89.0"	"6.90"	"613.98"	"6.24"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00400, Pf08625"	"10607"	"ENSG00000183751"	"TBL3"	"hsa:10607; Q12788; Q59GD6; Q8IVB7; Q96A78"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	"36.4"	"18.2"	"32.6"	"31.3"	"28.3"	"32.6"	"31.0"	"57.7"	"43.2"	"128.1"	"227.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49411"	"Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2"	"0.000"	""	"5"	"2"	"4"	"2"	"452"	"49.5"	"7.61"	"888.72"	"6.22"	"2"	"2"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"170.9"	"69.8"	"179.4"	"151.4"	"144.1"	"193.3"	"152.4"	"184.8"	"153.1"	"298.8"	"446.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H3G5"	"Probable serine carboxypeptidase CPVL OS=Homo sapiens OX=9606 GN=CPVL PE=1 SV=2"	"0.000"	""	"4"	"2"	"4"	"2"	"476"	"54.1"	"5.62"	"628.67"	"6.22"	"2"	"2"	"protein metabolism"	""	"other molecular function"	"Pf00450"	"54504"	"ENSG00000106066"	"CPVL"	"A4D1A4; hsa:54504; Q6UX20; Q8NBL7; Q96AR7; Q9H3G5; Q9HB41"	""	""	"0"	"0"	"84.7"	"37.7"	"76.5"	"66.5"	"71.7"	"93.8"	"71.3"	"115.4"	"133.4"	"351.2"	"855.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75717"	"WD repeat and HMG-box DNA-binding protein 1 OS=Homo sapiens OX=9606 GN=WDHD1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1129"	"125.9"	"5.62"	"533.95"	"6.21"	"1"	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400, Pf12341, Pf12894"	"11169"	"ENSG00000198554"	"WDHD1"	"C9JW18; F6W0U7; hsa:11169; O75717"	""	"Mesodermal commitment pathway"	"1"	"0"	"49.8"	"20.4"	"47.8"	"51.5"	"45.4"	"60.9"	"40.2"	"56.7"	"46.8"	"95.1"	"256.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02218"	"2-oxoglutarate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=OGDH PE=1 SV=3"	"0.000"	""	"3"	"2"	"4"	"2"	"1023"	"115.9"	"6.86"	"682.79"	"6.17"	"2"	"2"	"protein metabolism;other metabolic processes;developmental processes"	"other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00676, Pf02779, Pf16078, Pf16870"	"4967"	"ENSG00000105953"	"OGDH"	"B4E2U9; D3DVL0; E9PBM1; hsa:4967; Q02218; Q96DD3; Q9UDX0"	"Lysine catabolism; Glyoxylate metabolism and glycine degradation; Citric acid cycle (TCA cycle)"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Thiamine metabolic pathways; 7q11.23 copy number variation syndrome; TCA cycle (aka Krebs or citric acid cycle)"	"8"	"0"	"59.2"	"22.1"	"42.1"	"42.1"	"38.6"	"55.7"	"31.8"	"47.2"	"38.9"	"77.7"	"133.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86TJ2"	"Transcriptional adapter 2-beta OS=Homo sapiens OX=9606 GN=TADA2B PE=1 SV=2"	"0.000"	""	"5"	"2"	"4"	"2"	"420"	"48.4"	"7.83"	"667.07"	"6.16"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00249"	"93624"	"ENSG00000173011"	"TADA2B"	"A0AUJ8; A4QMR7; B3KSN0; B3KU86; hsa:93624; Q6MZG9; Q86TJ2"	"Ub-specific processing proteases; HATs acetylate histones"	""	"2"	"0"	"12.7"	"4.3"	"17.7"	"11.9"	"14.9"	"16.8"	"8.6"	"20.6"	"13.7"	"69.0"	"153.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49755"	"Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2"	"0.000"	""	"12"	"2"	"4"	"2"	"219"	"25.0"	"7.44"	"748.03"	"6.16"	"2"	"2"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"transporter activity;other molecular function"	"Pf01105"	"10972"	"ENSG00000170348"	"TMED10"	"B2R605; hsa:10972; P49755; Q15602; Q16536; Q86TC2; Q86TS5"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport; COPII-mediated vesicle transport; Cargo concentration in the ER"	"mRNA processing; 5q35 copy number variation"	"6"	"0"	"115.8"	"30.2"	"61.1"	"50.8"	"64.1"	"63.2"	"71.0"	"97.1"	"138.0"	"293.8"	"377.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6L8Q7"	"2',5'-phosphodiesterase 12 OS=Homo sapiens OX=9606 GN=PDE12 PE=1 SV=2"	"0.000"	""	"5"	"2"	"4"	"2"	"609"	"67.3"	"6.57"	"768.29"	"6.15"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf03372"	"201626"	"ENSG00000174840"	"PDE12"	"B4DTU8; hsa:201626; Q6L8Q7; Q8IYU3; Q8NDU2; Q8TE78"	"OAS antiviral response"	"Phosphodiesterases in neuronal function"	"2"	"0"	"84.3"	"45.7"	"70.9"	"69.5"	"70.8"	"78.7"	"73.5"	"101.0"	"106.0"	"364.8"	"1384.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09497"	"Clathrin light chain B OS=Homo sapiens OX=9606 GN=CLTB PE=1 SV=1"	"0.000"	""	"8"	"2"	"4"	"2"	"229"	"25.2"	"4.64"	"554.51"	"6.12"	"2"	"2"	"transport"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf01086"	"1212"	"ENSG00000175416"	"CLTB"	"hsa:1212; P09497; Q53Y37; Q6FHW1"	"Lysosome Vesicle Biogenesis; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; Formation of annular gap junctions"	"Ebola virus infection in host; Fragile X syndrome; 5q35 copy number variation"	"11"	"0"	"234.7"	"98.7"	"197.8"	"174.4"	"195.5"	"195.8"	"159.2"	"194.1"	"160.0"	"295.1"	"500.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y530"	"ADP-ribose glycohydrolase OARD1 OS=Homo sapiens OX=9606 GN=OARD1 PE=1 SV=2"	"0.000"	""	"13"	"2"	"4"	"2"	"152"	"17.0"	"8.31"	"670.16"	"6.11"	"2"	"2"	"protein metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf01661"	"221443"	"ENSG00000124596"	"OARD1"	"A6NEK4; A8K4H4; hsa:221443; Q96F23; Q9Y530"	""	""	"0"	"0"	"115.4"	"64.4"	"136.4"	"114.8"	"127.1"	"166.7"	"120.0"	"179.4"	"127.2"	"323.7"	"729.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11233"	"Ras-related protein Ral-A OS=Homo sapiens OX=9606 GN=RALA PE=1 SV=1"	"0.000"	""	"14"	"3"	"5"	"2"	"206"	"23.6"	"7.11"	"967.59"	"6.10"	"3"	"2"	"cell cycle OR cell proliferation;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00071"	"5898"	"ENSG00000006451"	"RALA"	"A4D1W3; hsa:5898; P11233"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; p38MAPK events"	"RalA downstream regulated genes; Chromosomal and microsatellite instability in colorectal cancer ; Ras signaling; Pancreatic adenocarcinoma pathway; EGF/EGFR signaling pathway"	"8"	"1"	"322.7"	"131.2"	"231.3"	"187.9"	"231.9"	"238.6"	"191.8"	"283.6"	"239.2"	"526.8"	"834.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02790"	"Peptidyl-prolyl cis-trans isomerase FKBP4 OS=Homo sapiens OX=9606 GN=FKBP4 PE=1 SV=3"	"0.000"	""	"6"	"3"	"5"	"3"	"459"	"51.8"	"5.43"	"1004.76"	"6.08"	"3"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00254, Pf00515"	"2288"	"ENSG00000004478"	"FKBP4"	"D3DUQ1; hsa:2288; Q02790; Q9UCP1; Q9UCV7"	"Estrogen-dependent gene expression; Potential therapeutics for SARS; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Attenuation phase"	"Androgen receptor signaling pathway"	"6"	"0"	"89.5"	"29.7"	"56.7"	"44.0"	"67.7"	"77.7"	"72.1"	"62.8"	"72.3"	"109.0"	"254.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19623"	"Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1"	"0.000"	""	"8"	"2"	"4"	"2"	"302"	"33.8"	"5.49"	"702.29"	"6.08"	"2"	"2"	"other metabolic processes;other biological processes"	"cytosol"	"other molecular function"	"Pf01564, Pf17284"	"6723"	"ENSG00000116649"	"SRM"	"B1AKP9; hsa:6723; P19623; Q15511"	"Metabolism of polyamines"	"Methionine de novo and salvage pathway; Amino acid metabolism"	"3"	"0"	"121.9"	"62.9"	"104.1"	"65.4"	"97.1"	"99.3"	"87.2"	"95.5"	"90.7"	"167.5"	"279.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P60228"	"Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1"	"0.000"	""	"8"	"3"	"5"	"3"	"445"	"52.2"	"6.04"	"894.08"	"6.07"	"3"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01399, Pf09440"	"3646"	"ENSG00000104408"	"EIF3E"	"hsa:3646; O43902; P60228; Q64058; Q64059; Q64252; Q6FG33; Q8WVK4"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"8"	"0"	"215.0"	"113.4"	"211.2"	"196.3"	"190.5"	"242.9"	"185.2"	"221.1"	"171.9"	"257.6"	"465.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60884"	"DnaJ homolog subfamily A member 2 OS=Homo sapiens OX=9606 GN=DNAJA2 PE=1 SV=1"	"0.000"	""	"5"	"2"	"4"	"2"	"412"	"45.7"	"6.48"	"605.44"	"6.06"	"2"	"2"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;other cell component"	"other molecular function"	"Pf00226, Pf00684, Pf01556"	"10294"	"ENSG00000069345"	"DNAJA2"	"B2R7L7; hsa:10294; O14711; O60884"	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand"	""	"1"	"0"	"225.9"	"101.0"	"197.9"	"151.4"	"183.0"	"208.8"	"179.0"	"206.9"	"187.5"	"382.3"	"715.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P0DPB6"	"DNA-directed RNA polymerases I and III subunit RPAC2 OS=Homo sapiens OX=9606 GN=POLR1D PE=1 SV=1"	"0.000"	""	"20"	"2"	"4"	"2"	"133"	"15.2"	"5.80"	"652.68"	"6.05"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13656"	"51082"	"ENSG00000186184"	"POLR1D"	"hsa:51082; P0DPB6; Q5TBX2; Q96BR3; Q9Y2S0"	""	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"4"	"0"	"98.0"	"42.9"	"86.5"	"70.9"	"82.5"	"94.4"	"68.9"	"129.3"	"233.5"	"603.3"	"1079.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14802"	"DNA-directed RNA polymerase III subunit RPC1 OS=Homo sapiens OX=9606 GN=POLR3A PE=1 SV=2"	"0.000"	""	"2"	"2"	"3"	"1"	"1390"	"155.5"	"8.48"	"384.44"	"6.04"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00623, Pf04983, Pf04997, Pf04998, Pf05000"	"11128"	"ENSG00000148606"	"POLR3A"	"hsa:11128; O14802; Q8IW34; Q8TCW5"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation"	"Pyrimidine metabolism; Cytosolic DNA-sensing pathway"	"9"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BTL3"	"RNA guanine-N7 methyltransferase activating subunit OS=Homo sapiens OX=9606 GN=RAMAC PE=1 SV=1"	"0.000"	""	"13"	"1"	"2"	"1"	"118"	"14.4"	"8.94"	"666.53"	"6.03"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf15320"	"83640"	"ENSG00000169612"	"RAMAC"	"hsa:83640; Q2M1J8; Q9BTL3"	""	"15q25 copy number variation"	"1"	"0"	"69.9"	"39.1"	"59.9"	"59.7"	"54.7"	"60.2"	"53.4"	"68.4"	"65.7"	"114.6"	"200.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P1N9"	"Putative deoxyribonuclease TATDN1 OS=Homo sapiens OX=9606 GN=TATDN1 PE=1 SV=2"	"0.001"	""	"8"	"2"	"3"	"2"	"297"	"33.6"	"6.96"	"232.60"	"6.02"	"1"	"2"	"DNA metabolism"	"nucleus"	"other molecular function"	"Pf01026"	"83940"	"ENSG00000147687"	"TATDN1"	"B2R5J0; hsa:83940; Q6P1N9; Q8TD02; Q9BY40"	""	""	"0"	"0"	"54.7"	"25.4"	"40.3"	"34.8"	"42.6"	"47.1"	"41.2"	"49.3"	"55.8"	"208.0"	"598.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WYP5"	"Protein ELYS OS=Homo sapiens OX=9606 GN=AHCTF1 PE=1 SV=3"	"0.000"	""	"1"	"2"	"4"	"2"	"2266"	"252.3"	"6.60"	"654.95"	"6.02"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf13934, Pf16687"	"25909"	"ENSG00000153207"	"AHCTF1"	"A6NGM0; A8MSG9; A8MZ86; hsa:25909; Q7Z4E3; Q8IZA4; Q8WYP5; Q96EH9; Q9Y4Q6"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Postmitotic nuclear pore complex (NPC) reformation"	"Gastric cancer network 2"	"8"	"0"	"44.3"	"19.7"	"37.6"	"29.1"	"36.3"	"42.9"	"32.3"	"43.4"	"32.6"	"54.6"	"102.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BRD0"	"BUD13 homolog OS=Homo sapiens OX=9606 GN=BUD13 PE=1 SV=1"	"0.001"	""	"3"	"2"	"3"	"2"	"619"	"70.5"	"9.86"	"252.22"	"6.02"	"1"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf09736"	"84811"	"ENSG00000137656"	"BUD13"	"A8K0S0; hsa:84811; Q96LS7; Q9BRD0"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"75.8"	"54.1"	"49.3"	"53.5"	"58.9"	"67.7"	"71.5"	"93.0"	"102.7"	"154.0"	"238.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14258"	"E3 ubiquitin/ISG15 ligase TRIM25 OS=Homo sapiens OX=9606 GN=TRIM25 PE=1 SV=2"	"0.000"	""	"4"	"2"	"3"	"2"	"630"	"70.9"	"8.09"	"400.42"	"6.01"	"1"	"2"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00622, Pf13445, Pf13765"	"7706"	"ENSG00000121060"	"TRIM25"	"hsa:7706; Q14258"	"SARS-CoV-1 activates/modulates innate immune responses; Termination of translesion DNA synthesis; Interferon gamma signaling; ISG15 antiviral mechanism; SARS-CoV-2 activates/modulates innate and adaptive immune responses; TRAF6 mediated NF-kB activation; NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10; Negative regulators of DDX58/IFIH1 signaling; Ovarian tumor domain proteases; TRAF3-dependent IRF activation pathway; TRAF6 mediated IRF7 activation"	"Novel intracellular components of RIG-I-like receptor pathway; Cytosolic DNA-sensing pathway; SARS-CoV-2 innate immunity evasion and cell-specific immune response; 1p36 copy number variation syndrome"	"16"	"0"	"6.3"	"5.2"	"8.7"	"8.1"	"7.5"	"5.8"	"8.4"	"7.9"	"7.4"	"19.3"	"28.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15212"	"Prefoldin subunit 6 OS=Homo sapiens OX=9606 GN=PFDN6 PE=1 SV=1"	"0.000"	""	"16"	"2"	"4"	"2"	"129"	"14.6"	"8.88"	"605.70"	"6.01"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"other cell component"	"other molecular function"	"Pf01920"	"10471"	"ENSG00000204220; ENSG00000206283; ENSG00000224782; ENSG00000235692; ENSG00000237335"	"PFDN6"	"hsa:10471; O15212"	"Prefoldin mediated transfer of substrate  to CCT/TriC"	"Cellular proteostasis"	"2"	"0"	"100.7"	"42.3"	"83.9"	"64.0"	"83.0"	"92.6"	"78.9"	"89.0"	"67.6"	"123.3"	"255.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P20962"	"Parathymosin OS=Homo sapiens OX=9606 GN=PTMS PE=1 SV=2"	"0.000"	""	"11"	"1"	"4"	"1"	"102"	"11.5"	"4.16"	"805.16"	"5.98"	"1"	"1"	"DNA metabolism;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf03247"	"5763"	"ENSG00000159335"	"PTMS"	"hsa:5763; P20962"	""	"IL-18 signaling pathway"	"1"	"0"	"428.6"	"222.2"	"393.0"	"425.6"	"481.7"	"513.7"	"440.1"	"509.0"	"299.6"	"437.6"	"763.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z2W4"	"Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3"	"0.000"	""	"2"	"2"	"4"	"2"	"902"	"101.4"	"8.40"	"658.80"	"5.97"	"2"	"2"	"stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00644, Pf02825, Pf18606, Pf18633"	"56829"	"ENSG00000105939"	"ZC3HAV1"	"A4D1R2; A4D1S4; hsa:56829; Q7Z2W4; Q8IW57; Q8TAJ3; Q96N79; Q9H8R9; Q9P0Y7"	"Signaling by BRAF and RAF1 fusions"	""	"1"	"0"	"192.1"	"76.9"	"141.8"	"145.0"	"171.9"	"182.9"	"132.3"	"191.4"	"136.7"	"271.9"	"520.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z7K0"	"COX assembly mitochondrial protein homolog OS=Homo sapiens OX=9606 GN=CMC1 PE=1 SV=1"	"0.001"	""	"22"	"2"	"2"	"2"	"106"	"12.5"	"8.63"	"237.45"	"5.96"	"1"	"1"	""	"mitochondrion"	"other molecular function"	"Pf08583"	"152100"	"ENSG00000187118"	"CMC1"	"hsa:152100; Q68DJ7; Q7Z7K0"	""	"Mitochondrial complex IV assembly"	"1"	"0"	"266.6"	"134.4"	"220.6"	"214.0"	"252.8"	"284.4"	"231.0"	"281.7"	"178.9"	"367.2"	"462.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43818"	"U3 small nucleolar RNA-interacting protein 2 OS=Homo sapiens OX=9606 GN=RRP9 PE=1 SV=1"	"0.000"	""	"4"	"2"	"3"	"2"	"475"	"51.8"	"7.85"	"328.83"	"5.94"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00400"	"9136"	"ENSG00000114767"	"RRP9"	"B2R996; hsa:9136; O43818; Q8IZ30"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	"229.0"	"114.7"	"200.4"	"192.1"	"227.8"	"242.6"	"207.5"	"253.9"	"201.2"	"363.1"	"621.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NZM3"	"Intersectin-2 OS=Homo sapiens OX=9606 GN=ITSN2 PE=1 SV=3"	"0.000"	""	"1"	"2"	"4"	"2"	"1697"	"193.3"	"8.12"	"591.76"	"5.93"	"2"	"2"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00018, Pf00168, Pf00621, Pf07653, Pf12763, Pf14604, Pf16652"	"50618"	"ENSG00000198399"	"ITSN2"	"hsa:50618; O95062; Q15812; Q9HAK4; Q9NXE6; Q9NYG0; Q9NZM2; Q9NZM3; Q9ULG4"	"Cargo recognition for clathrin-mediated endocytosis; RHOU GTPase cycle"	""	"3"	"0"	"15.7"	"4.8"	"15.4"	"12.0"	"12.3"	"18.8"	"25.6"	"62.3"	"59.7"	"167.0"	"168.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NRW3"	"DNA dC->dU-editing enzyme APOBEC-3C OS=Homo sapiens OX=9606 GN=APOBEC3C PE=1 SV=2"	""	""	"12"	"2"	"2"	"2"	"190"	"22.8"	"7.59"	""	"5.93"	""	"2"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf18782"	"27350"	"ENSG00000244509"	"APOBEC3C"	"B2R884; hsa:27350; Q5JZ92; Q7Z2N7; Q96F12; Q9NRW3"	"Formation of the Editosome"	""	"2"	"0"	"87.6"	"22.0"	"81.7"	"90.2"	"66.7"	"115.1"	"76.6"	"86.9"	"68.7"	"129.3"	"180.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09471"	"Guanine nucleotide-binding protein G(o) subunit alpha OS=Homo sapiens OX=9606 GN=GNAO1 PE=1 SV=4"	"0.000"	""	"8"	"2"	"4"	"1"	"354"	"40.0"	"5.53"	"651.26"	"5.92"	"2"	"2"	"signal transduction;other biological processes"	"plasma membrane;other membranes"	"signal transduction activity or receptor binding;other molecular function"	"Pf00503"	"2775"	"ENSG00000087258"	"GNAO1"	"hsa:2775; P09471; P29777; Q8TD72; Q9UMV4"	"Ca2+ pathway"	"Thyroid stimulating hormone (TSH) signaling pathway; Corticotropin-releasing hormone signaling pathway; G protein signaling pathways; Rett syndrome causing genes; Male infertility; Purinergic signaling; Calcium regulation in cardiac cells; Serotonin HTR1 group and FOS pathway"	"9"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P83881"	"60S ribosomal protein L36a OS=Homo sapiens OX=9606 GN=RPL36A PE=1 SV=2"	"0.000"	""	"20"	"2"	"3"	"2"	"106"	"12.4"	"10.58"	"338.72"	"5.92"	"1"	"2"	"protein metabolism;other metabolic processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;translational apparatus"	"other molecular function"	"Pf00935"	"6173"	"ENSG00000241343"	"RPL36A"	"hsa:6173; P09896; P10661; P83881; Q08ES5; Q5J9I6"	"GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"592.5"	"231.5"	"502.2"	"483.7"	"463.9"	"564.3"	"412.6"	"549.6"	"376.9"	"694.2"	"934.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UJS0"	"Calcium-binding mitochondrial carrier protein Aralar2 OS=Homo sapiens OX=9606 GN=SLC25A13 PE=1 SV=2"	"0.000"	""	"6"	"3"	"5"	"3"	"675"	"74.1"	"8.62"	"996.19"	"5.91"	"3"	"2"	"other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00153"	"10165"	"ENSG00000004864"	"SLC25A13"	"hsa:10165; O14566; O14575; Q546F9; Q9NZW1; Q9UJS0; Q9UNI7"	"Gluconeogenesis; Mitochondrial protein import; Aspartate and asparagine metabolism"	""	"3"	"0"	"86.4"	"41.4"	"68.4"	"63.1"	"73.9"	"82.5"	"76.7"	"89.3"	"83.9"	"155.9"	"291.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NYU2"	"UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3"	"0.000"	""	"2"	"2"	"3"	"2"	"1555"	"177.1"	"5.63"	"329.90"	"5.89"	"1"	"2"	"protein metabolism;other metabolic processes;stress response"	"ER/Golgi;other cell component"	"other molecular function"	"Pf06427, Pf18400, Pf18401, Pf18402, Pf18403, Pf18404"	"56886"	"ENSG00000136731"	"UGGT1"	"hsa:56886; Q53QP2; Q53SL3; Q8IW30; Q9H8I4; Q9NYU2"	"ER Quality Control Compartment (ERQC)"	"IL-18 signaling pathway"	"2"	"0"	"80.7"	"43.0"	"82.1"	"69.5"	"83.4"	"91.8"	"62.0"	"87.4"	"75.7"	"111.6"	"207.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N442"	"Translation factor GUF1, mitochondrial OS=Homo sapiens OX=9606 GN=GUF1 PE=1 SV=1"	"0.001"	""	"4"	"2"	"3"	"2"	"669"	"74.3"	"8.59"	"271.32"	"5.88"	"1"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion"	"translation activity;other molecular function"	"Pf00009, Pf00679, Pf03144, Pf06421"	"60558"	"ENSG00000151806"	"GUF1"	"hsa:60558; Q5XKM8; Q8N442; Q9H710; Q9H8U4"	""	""	"0"	"0"	"38.8"	"12.9"	"23.3"	"20.7"	"29.7"	"31.2"	"30.1"	"45.5"	"50.1"	"171.5"	"273.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NQT4"	"Exosome complex component RRP46 OS=Homo sapiens OX=9606 GN=EXOSC5 PE=1 SV=1"	"0.000"	""	"8"	"2"	"4"	"2"	"235"	"25.2"	"7.59"	"768.21"	"5.88"	"2"	"2"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01138, Pf03725"	"56915"	"ENSG00000077348"	"EXOSC5"	"hsa:56915; Q32Q81; Q8NG16; Q96I89; Q9NQT4"	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	""	"6"	"0"	"236.2"	"84.3"	"171.3"	"159.1"	"195.3"	"202.6"	"141.9"	"234.3"	"205.4"	"405.4"	"699.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15511"	"Actin-related protein 2/3 complex subunit 5 OS=Homo sapiens OX=9606 GN=ARPC5 PE=1 SV=3"	"0.000"	""	"8"	"1"	"4"	"1"	"151"	"16.3"	"5.67"	"808.26"	"5.87"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf04699"	"10092"	"ENSG00000162704"	"ARPC5"	"A6NEC4; hsa:10092; O15511; Q6PG42"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Neutrophil degranulation; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"Pathogenic Escherichia coli infection; Regulation of actin cytoskeleton"	"8"	"0"	"172.4"	"72.3"	"143.2"	"117.2"	"142.2"	"160.8"	"121.0"	"167.9"	"132.5"	"739.5"	"2055.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4F1"	"FERM, ARHGEF and pleckstrin domain-containing protein 1 OS=Homo sapiens OX=9606 GN=FARP1 PE=1 SV=1"	"0.000"	""	"2"	"3"	"5"	"3"	"1045"	"118.6"	"8.15"	"882.27"	"5.87"	"3"	"2"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00169, Pf00373, Pf00621, Pf08736, Pf09379, Pf09380"	"10160"	"ENSG00000152767"	"FARP1"	"hsa:10160; Q5JVI9; Q6IQ29; Q9Y4F1"	"RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOF GTPase cycle"	""	"4"	"0"	"526.2"	"196.0"	"515.6"	"409.0"	"489.5"	"579.4"	"402.4"	"535.1"	"414.9"	"1063.5"	"1950.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14696"	"LRP chaperone MESD OS=Homo sapiens OX=9606 GN=MESD PE=1 SV=2"	"0.000"	""	"10"	"2"	"4"	"2"	"234"	"26.1"	"7.78"	"822.70"	"5.86"	"2"	"2"	"cell-cell signaling;protein metabolism;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi"	"signal transduction activity or receptor binding;other molecular function"	"Pf10185"	"23184"	"ENSG00000117899"	"MESD"	"B4DW84; D3DW96; hsa:23184; Q14696; Q969U1"	""	""	"0"	"0"	"221.6"	"95.5"	"223.5"	"219.6"	"252.5"	"276.1"	"222.9"	"288.4"	"162.2"	"570.6"	"2131.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O15116"	"U6 snRNA-associated Sm-like protein LSm1 OS=Homo sapiens OX=9606 GN=LSM1 PE=1 SV=1"	""	""	"19"	"1"	"1"	"1"	"133"	"15.2"	"5.22"	""	"5.86"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	"27257"	"ENSG00000175324"	"LSM1"	"B2R5E6; hsa:27257; O15116"	"mRNA decay by 5' to 3' exoribonuclease"	""	"1"	"0"	"27.0"	"8.0"	"25.1"	"21.0"	"26.0"	"26.0"	"19.4"	"26.3"	"20.8"	"46.1"	"57.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43707"	"Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"911"	"104.8"	"5.44"	"587.87"	"5.86"	"1"	"1"	"cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00307, Pf00435, Pf08726"	"81"	"ENSG00000130402; ENSG00000282844"	"ACTN4"	"A4K467; D6PXK4; hsa:81; O43707; O76048"	"Platelet degranulation ; Nephrin family interactions"	"Arrhythmogenic right ventricular cardiomyopathy; Primary focal segmental glomerulosclerosis (FSGS); Focal adhesion; Striated muscle contraction pathway; Ebola virus infection in host; Nephrotic syndrome; Alstrom syndrome"	"9"	"0"	"146.9"	"48.1"	"99.9"	"78.3"	"111.2"	"107.5"	"85.7"	"115.6"	"105.9"	"163.0"	"287.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14254"	"Flotillin-2 OS=Homo sapiens OX=9606 GN=FLOT2 PE=1 SV=2"	"0.000"	""	"5"	"2"	"3"	"2"	"428"	"47.0"	"5.25"	"485.77"	"5.85"	"1"	"2"	"cell adhesion;transport;other biological processes"	"plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	""	"Pf01145"	"2319"	"ENSG00000132589"	"FLOT2"	"hsa:2319; Q14254"	"RHOA GTPase cycle; RHOB GTPase cycle; RND1 GTPase cycle; RND3 GTPase cycle; RHOC GTPase cycle; Regulation of necroptotic cell death; Synaptic adhesion-like molecules"	"Angiopoietin-like protein 8 regulatory pathway; Insulin signaling"	"10"	"0"	"196.8"	"55.9"	"81.6"	"68.9"	"125.9"	"96.5"	"70.6"	"104.7"	"84.1"	"180.2"	"294.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H974"	"Queuine tRNA-ribosyltransferase accessory subunit 2 OS=Homo sapiens OX=9606 GN=QTRT2 PE=1 SV=1"	""	""	"5"	"1"	"1"	"1"	"415"	"46.7"	"6.81"	""	"5.85"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf01702"	"79691"	"ENSG00000151576"	"QTRT2"	"A6NGE9; B7Z472; B7Z5R2; hsa:79691; J3KR78; Q6IA59; Q9H974"	"tRNA modification in the nucleus and cytosol"	""	"1"	"0"	"28.1"	"13.5"	"18.8"	"18.4"	"26.0"	"29.2"	"19.6"	"26.8"	"33.8"	"57.5"	"113.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25398"	"40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3"	"0.000"	""	"14"	"3"	"6"	"3"	"132"	"14.5"	"7.21"	"1290.76"	"5.82"	"3"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01248"	"6206"	"ENSG00000112306"	"RPS12"	"hsa:6206; P25398; Q76M58"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"1024.1"	"469.3"	"865.5"	"816.1"	"836.1"	"1031.3"	"745.5"	"1008.1"	"718.8"	"1447.3"	"2272.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O43678"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 OS=Homo sapiens OX=9606 GN=NDUFA2 PE=1 SV=3"	""	""	"21"	"1"	"1"	"1"	"99"	"10.9"	"9.57"	""	"5.82"	""	"1"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes"	"other membranes;mitochondrion"	"transporter activity"	"Pf05047"	"4695"	"ENSG00000131495"	"NDUFA2"	"D6RJD6; hsa:4695; O43678; Q6IAY8"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"5"	"0"	"43.4"	"18.0"	"28.8"	"24.8"	"26.9"	"33.1"	"25.8"	"32.6"	"38.8"	"80.4"	"157.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14936"	"Peripheral plasma membrane protein CASK OS=Homo sapiens OX=9606 GN=CASK PE=1 SV=3"	"0.000"	""	"3"	"2"	"3"	"2"	"926"	"105.1"	"6.43"	"491.13"	"5.81"	"1"	"2"	"cell adhesion;protein metabolism;other metabolic processes;transport;other biological processes"	"extracellular matrix;plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf00018, Pf00069, Pf00595, Pf00625, Pf02828"	"8573"	"ENSG00000147044"	"CASK"	"A6NES1; B7ZKY0; hsa:8573; O14936; O43215; Q17RI4; Q59HA0; Q5VT16; Q5VT17; Q5VT18; Q5VT19; Q66T42; Q9BYH6; Q9NYB2; Q9NYB3"	"Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Assembly and cell surface presentation of NMDA receptors; Nephrin family interactions; Neurexins and neuroligins; Dopamine Neurotransmitter Release Cycle; Syndecan interactions"	"Parkin-ubiquitin proteasomal system pathway; Splicing factor NOVA regulated synaptic proteins"	"9"	"0"	"239.9"	"117.8"	"215.0"	"208.4"	"212.8"	"247.0"	"198.1"	"236.2"	"187.4"	"363.2"	"531.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q3B726"	"DNA-directed RNA polymerase I subunit RPA43 OS=Homo sapiens OX=9606 GN=TWISTNB PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"338"	"37.4"	"6.98"	"583.26"	"5.80"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf17875"	"221830"	"ENSG00000105849"	"POLR1F"	"A0PJ45; B7Z724; hsa:221830; Q3B726"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"Pyrimidine metabolism; 2q13 copy number variation syndrome"	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q04637"	"Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4"	"0.000"	""	"1"	"2"	"4"	"2"	"1599"	"175.4"	"5.33"	"608.45"	"5.79"	"2"	"2"	"protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02020, Pf02847, Pf02854"	"1981"	"ENSG00000114867"	"EIF4G1"	"D3DNT2; D3DNT4; D3DNT5; E9PFM1; G5E9S1; hsa:1981; O43177; O95066; Q04637; Q5HYG0; Q6ZN21; Q8N102"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); AUF1 (hnRNP D0) binds and destabilizes mRNA; Deadenylation of mRNA; ISG15 antiviral mechanism; mTORC1-mediated signalling"	"Translation factors; VEGFA-VEGFR2 signaling; Acute viral myocarditis; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Pleural mesothelioma"	"18"	"0"	"86.7"	"29.6"	"59.8"	"50.6"	"61.9"	"55.1"	"56.5"	"68.6"	"55.8"	"91.7"	"158.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99633"	"Pre-mRNA-splicing factor 18 OS=Homo sapiens OX=9606 GN=PRPF18 PE=1 SV=1"	"0.000"	""	"6"	"2"	"3"	"2"	"342"	"39.8"	"8.15"	"340.77"	"5.78"	"1"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf02840, Pf08799"	"8559"	"ENSG00000165630"	"PRPF18"	"hsa:8559; Q5T9P9; Q99633; Q9BUI9"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"0"	"81.0"	"36.1"	"59.8"	"48.8"	"61.2"	"73.9"	"58.9"	"73.6"	"78.8"	"420.4"	"1366.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92878"	"DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1"	"0.000"	""	"2"	"2"	"4"	"2"	"1312"	"153.8"	"6.89"	"746.39"	"5.78"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04423, Pf13476, Pf13558"	"10111"	"ENSG00000113522"	"RAD50"	"B9EGF5; hsa:10111; O43254; Q6GMT7; Q6P5X3; Q92878; Q9UP86"	"Sensing of DNA Double Strand Breaks; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Resolution of D-loop Structures through Holliday Junction Intermediates; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; Meiotic recombination; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; DNA Damage/Telomere Stress Induced Senescence; Nonhomologous End-Joining (NHEJ); HDR through MMEJ (alt-NHEJ)"	"miRNA regulation of DNA damage response; Homologous recombination; DDX1 as a regulatory component of the Drosha microprocessor; ATM signaling in development and disease ; Breast cancer pathway; Joubert syndrome; DNA repair pathways, full network; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; DNA damage response"	"29"	"0"	"181.2"	"74.7"	"128.0"	"121.5"	"130.4"	"129.2"	"117.3"	"154.8"	"131.6"	"230.6"	"460.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63173"	"60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2"	"0.000"	""	"33"	"3"	"6"	"2"	"70"	"8.2"	"10.10"	"1059.92"	"5.78"	"3"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01781"	"6169"	"ENSG00000172809"	"RPL38"	"B2R5A8; hsa:6169; P23411; P63173"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Mesodermal commitment pathway; Mesodermal commitment pathway; Cytoplasmic ribosomal proteins"	"16"	"0"	"127.8"	"48.3"	"109.6"	"108.7"	"112.7"	"129.7"	"84.9"	"127.0"	"118.6"	"343.9"	"604.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15437"	"Protein transport protein Sec23B OS=Homo sapiens OX=9606 GN=SEC23B PE=1 SV=2"	"0.000"	""	"2"	"1"	"5"	"1"	"767"	"86.4"	"6.89"	"1186.64"	"5.77"	"1"	"1"	"cell organization and biogenesis;transport"	"other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00626, Pf04810, Pf04811, Pf04815, Pf08033"	"10483"	"ENSG00000101310"	"SEC23B"	"D3DW33; hsa:10483; Q15437; Q503A9; Q5W183; Q9BS15; Q9BSI2; Q9H1D7"	""	"Sterol regulatory element-binding proteins (SREBP) signaling"	"1"	"0"	"10.3"	"5.2"	"19.3"	"19.8"	"17.4"	"19.8"	"16.6"	"16.2"	"8.4"	"14.7"	"23.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00268"	"Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"2"	"1085"	"110.0"	"9.94"	"780.51"	"5.76"	"2"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf05236, Pf07531"	"6874"	"ENSG00000130699"	"TAF4"	"A6NGD9; hsa:6874; O00268; Q5TBP6; Q99721; Q9BR40; Q9BX42"	"RNA Polymerase II Pre-transcription Events; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; Regulation of TP53 Activity through Phosphorylation; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation"	""	"9"	"0"	"74.8"	"27.9"	"67.3"	"53.3"	"61.1"	"77.3"	"52.6"	"64.7"	"61.0"	"128.2"	"196.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BWU0"	"Kanadaptin OS=Homo sapiens OX=9606 GN=SLC4A1AP PE=1 SV=1"	"0.000"	""	"5"	"3"	"4"	"3"	"796"	"88.8"	"5.19"	"813.54"	"5.76"	"2"	"2"	""	"plasma membrane;other membranes;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00498"	"22950"	"ENSG00000163798"	"SLC4A1AP"	"A6NJ39; hsa:22950; Q4KMT1; Q4KMX0; Q7Z5Q9; Q9BWU0; Q9NVN2"	""	""	"0"	"0"	"162.3"	"63.8"	"126.8"	"123.7"	"121.3"	"156.0"	"116.8"	"142.7"	"112.0"	"172.5"	"312.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P59998"	"Actin-related protein 2/3 complex subunit 4 OS=Homo sapiens OX=9606 GN=ARPC4 PE=1 SV=3"	"0.000"	""	"18"	"3"	"5"	"3"	"168"	"19.7"	"8.43"	"1090.42"	"5.75"	"3"	"2"	"cell organization and biogenesis"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf05856"	"10093"	"ENSG00000241553"	"ARPC4"	"C9JWM7; E7ETI0; F6TTL5; hsa:10093; O15509; P59998; Q6P0W5; Q96QJ3"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"Pathogenic Escherichia coli infection"	"6"	"0"	"151.8"	"77.7"	"127.1"	"103.2"	"113.5"	"149.8"	"112.8"	"151.6"	"158.8"	"1108.7"	"3174.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N5N7"	"39S ribosomal protein L50, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL50 PE=1 SV=2"	"0.000"	""	"13"	"1"	"2"	"1"	"158"	"18.3"	"7.88"	"446.96"	"5.74"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;cytosol;mitochondrion;translational apparatus"	""	"Pf10501"	"54534"	"ENSG00000136897"	"MRPL50"	"B7Z358; hsa:54534; Q5T7E0; Q8N5N7; Q9NX15"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"10.4"	"0.0"	"11.3"	"8.4"	"10.9"	"8.1"	"7.5"	"12.8"	"9.4"	"18.7"	"40.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16643"	"Drebrin OS=Homo sapiens OX=9606 GN=DBN1 PE=1 SV=4"	"0.000"	""	"3"	"2"	"4"	"2"	"649"	"71.4"	"4.45"	"797.30"	"5.73"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00241"	"1627"	"ENSG00000113758"	"DBN1"	"A8MV58; B2RBG0; hsa:1627; Q16643; Q9UFZ5"	"RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle; RHOH GTPase cycle; RHOD GTPase cycle"	"5q35 copy number variation"	"5"	"0"	"339.0"	"116.7"	"256.1"	"180.0"	"247.0"	"249.5"	"205.6"	"235.1"	"231.3"	"374.6"	"622.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5B9"	"FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1"	"0.000"	""	"2"	"2"	"4"	"2"	"1047"	"119.8"	"5.66"	"631.07"	"5.70"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus"	"other molecular function"	"Pf00557, Pf08512, Pf08644, Pf14826"	"11198"	"ENSG00000092201"	"SUPT16H"	"hsa:11198; Q6GMT8; Q6P2F1; Q6PJM1; Q9NRX0; Q9Y5B9"	"Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; Regulation of TP53 Activity through Phosphorylation"	""	"12"	"0"	"63.0"	"26.9"	"62.0"	"51.4"	"51.3"	"67.8"	"45.5"	"65.7"	"57.9"	"109.2"	"168.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42677"	"40S ribosomal protein S27 OS=Homo sapiens OX=9606 GN=RPS27 PE=1 SV=3"	"0.000"	""	"25"	"2"	"4"	"2"	"84"	"9.5"	"9.45"	"502.91"	"5.70"	"2"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01667"	"6232"	"ENSG00000177954"	"RPS27"	"hsa:6232; P42677; Q5T4L6"	"Regulation of expression of SLITs and ROBOs; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"25"	"0"	"369.1"	"182.7"	"305.4"	"294.1"	"263.6"	"331.0"	"264.3"	"334.3"	"256.7"	"534.0"	"934.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L804"	"Rab11 family-interacting protein 2 OS=Homo sapiens OX=9606 GN=RAB11FIP2 PE=1 SV=1"	"0.000"	""	"7"	"3"	"5"	"3"	"512"	"58.2"	"9.32"	"1045.38"	"5.69"	"3"	"2"	"cell-cell signaling;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00168, Pf09457"	"22841"	"ENSG00000107560"	"RAB11FIP2"	"A6NEI4; hsa:22841; Q3I768; Q7L804; Q9Y2F0"	"Vasopressin regulates renal water homeostasis via Aquaporins"	""	"1"	"0"	"67.4"	"26.3"	"49.8"	"55.8"	"60.8"	"89.0"	"120.4"	"292.1"	"240.3"	"571.8"	"521.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q17R31"	"Putative deoxyribonuclease TATDN3 OS=Homo sapiens OX=9606 GN=TATDN3 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"274"	"30.3"	"7.15"	"710.91"	"5.67"	"1"	"1"	""	"nucleus"	"other molecular function"	"Pf01026"	"128387"	"ENSG00000203705"	"TATDN3"	"A6NGS3; B7Z1C1; B7Z978; B7ZLQ6; E9PJE5; E9PNH3; G3V151; hsa:128387; Q17R31; Q4G0L1"	""	""	"0"	"0"	"30.4"	"11.9"	"24.1"	"22.0"	"25.9"	"27.5"	"28.9"	"41.7"	"51.7"	"198.2"	"768.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UNE7"	"E3 ubiquitin-protein ligase CHIP OS=Homo sapiens OX=9606 GN=STUB1 PE=1 SV=2"	"0.000"	""	"11"	"2"	"2"	"2"	"303"	"34.8"	"5.87"	"454.41"	"5.65"	"1"	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf04564, Pf12895, Pf18391"	"10273"	"ENSG00000103266"	"STUB1"	"A2IDB9; hsa:10273; O60526; Q969U2; Q9HBT1; Q9UNE7"	"Antigen processing: Ubiquitination & Proteasome degradation; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Regulation of necroptotic cell death; Downregulation of ERBB2 signaling; Regulation of TNFR1 signaling; Downregulation of TGF-beta receptor signaling"	"Androgen receptor signaling pathway; Parkin-ubiquitin proteasomal system pathway"	"10"	"0"	"252.0"	"99.3"	"238.5"	"196.8"	"189.8"	"271.2"	"211.8"	"253.0"	"228.8"	"372.9"	"548.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVC6"	"Mediator of RNA polymerase II transcription subunit 17 OS=Homo sapiens OX=9606 GN=MED17 PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"651"	"72.8"	"7.44"	"297.39"	"5.63"	"1"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf10156"	"9440"	"ENSG00000042429"	"MED17"	"B3KN07; hsa:9440; Q9HA81; Q9NVC6; Q9UNP7; Q9Y2W0; Q9Y660"	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; Generic Transcription Pathway"	""	"3"	"0"	"30.2"	"13.1"	"36.2"	"32.0"	"25.8"	"33.8"	"31.2"	"45.0"	"31.7"	"72.0"	"175.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N4T8"	"Carbonyl reductase family member 4 OS=Homo sapiens OX=9606 GN=CBR4 PE=1 SV=3"	"0.000"	""	"8"	"2"	"4"	"2"	"237"	"25.3"	"9.33"	"641.37"	"5.63"	"2"	"2"	"cell organization and biogenesis;other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf13561"	"84869"	"ENSG00000145439"	"CBR4"	"hsa:84869; Q8N4T8; Q8WTW8; Q96K93"	"Fatty acyl-CoA biosynthesis"	""	"1"	"0"	"108.0"	"59.0"	"98.0"	"97.1"	"105.2"	"101.2"	"90.3"	"115.7"	"97.9"	"178.9"	"320.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BSD7"	"Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1"	"0.000"	""	"13"	"2"	"5"	"2"	"190"	"20.7"	"9.54"	"1041.57"	"5.62"	"2"	"2"	""	""	"other molecular function"	"Pf03266"	"84284"	"ENSG00000135778"	"NTPCR"	"hsa:84284; Q9BSD7"	""	""	"0"	"0"	"60.8"	"29.8"	"53.9"	"46.4"	"60.4"	"60.3"	"42.4"	"73.5"	"80.8"	"399.4"	"738.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y333"	"U6 snRNA-associated Sm-like protein LSm2 OS=Homo sapiens OX=9606 GN=LSM2 PE=1 SV=1"	"0.000"	""	"16"	"2"	"4"	"2"	"95"	"10.8"	"6.52"	"608.16"	"5.61"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01423"	"57819"	"ENSG00000172850; ENSG00000204392; ENSG00000224979; ENSG00000225998; ENSG00000231502; ENSG00000236826"	"LSM2"	"hsa:57819; Q6FGG1; Q9Y333"	"mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease"	"mRNA processing"	"3"	"0"	"626.6"	"171.7"	"441.3"	"344.8"	"444.4"	"494.6"	"359.0"	"515.4"	"410.3"	"659.4"	"1035.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A8MWD9"	"Putative small nuclear ribonucleoprotein G-like protein 15 OS=Homo sapiens OX=9606 GN=SNRPGP15 PE=5 SV=2"	"0.000"	""	"25"	"2"	"4"	"2"	"76"	"8.5"	"8.84"	"692.44"	"5.61"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	""	""	"SNRPGP15"	"A8MWD9"	""	""	"0"	"0"	"316.5"	"131.9"	"226.4"	"188.6"	"245.3"	"287.4"	"234.8"	"324.4"	"267.1"	"395.2"	"550.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKL0"	"REST corepressor 1 OS=Homo sapiens OX=9606 GN=RCOR1 PE=1 SV=2"	"0.000"	""	"5"	"2"	"4"	"1"	"485"	"53.3"	"7.03"	"811.89"	"5.59"	"2"	"2"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00249, Pf01448"	"23186"	"ENSG00000089902"	"RCOR1"	"hsa:23186; J3KN32; Q15044; Q6P2I9; Q86VG5; Q9UKL0"	"Regulation of PTEN gene transcription; Factors involved in megakaryocyte development and platelet production; Potential therapeutics for SARS; HDACs deacetylate histones"	""	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16543"	"Hsp90 co-chaperone Cdc37 OS=Homo sapiens OX=9606 GN=CDC37 PE=1 SV=1"	"0.000"	""	"6"	"2"	"3"	"2"	"378"	"44.4"	"5.25"	"513.47"	"5.56"	"1"	"2"	"protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity;other molecular function"	"Pf03234, Pf08564, Pf08565"	"11140"	"ENSG00000105401"	"CDC37"	"hsa:11140; Q16543; Q53YA2"	"Regulation of necroptotic cell death; Downregulation of ERBB2 signaling; Signaling by ERBB2 KD Mutants; Signaling by ERBB2 TMD/JMD mutants; RHOBTB2 GTPase cycle; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; Constitutive Signaling by EGFRvIII; Signaling by ERBB2 ECD mutants; Constitutive Signaling by Overexpressed ERBB2; Drug-mediated inhibition of ERBB2 signaling; Resistance of ERBB2 KD mutants to trastuzumab; Resistance of ERBB2 KD mutants to sapitinib; Resistance of ERBB2 KD mutants to tesevatinib; Resistance of ERBB2 KD mutants to neratinib; Resistance of ERBB2 KD mutants to osimertinib; Resistance of ERBB2 KD mutants to afatinib; Resistance of ERBB2 KD mutants to AEE788; Resistance of ERBB2 KD mutants to lapatinib; Drug resistance in ERBB2 TMD/JMD mutants"	"TNF-alpha signaling pathway; Aryl hydrocarbon receptor pathway; Aryl hydrocarbon receptor pathway; Nuclear receptors meta-pathway; Interactions between LOXL4 and oxidative stress pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway"	"27"	"0"	"350.9"	"106.6"	"290.5"	"264.2"	"308.9"	"349.8"	"216.7"	"289.1"	"179.0"	"323.9"	"636.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42566"	"Epidermal growth factor receptor substrate 15 OS=Homo sapiens OX=9606 GN=EPS15 PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"896"	"98.6"	"4.64"	"790.17"	"5.56"	"2"	"1"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	""	"2060"	"ENSG00000085832"	"EPS15"	"B2R8J7; D3DPJ2; hsa:2060; P42566; Q5SRH4"	"Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation; Negative regulation of MET activity; InlB-mediated entry of Listeria monocytogenes into host cell"	"VEGFA-VEGFR2 signaling; Ebola virus infection in host; EGF/EGFR signaling pathway"	"8"	"0"	"35.7"	"18.0"	"37.2"	"30.7"	"37.4"	"50.0"	"22.9"	"37.4"	"31.7"	"58.9"	"93.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VTL8"	"Pre-mRNA-splicing factor 38B OS=Homo sapiens OX=9606 GN=PRPF38B PE=1 SV=1"	"0.000"	""	"3"	"2"	"4"	"2"	"546"	"64.4"	"10.54"	"625.73"	"5.53"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf03371"	"55119"	"ENSG00000134186"	"PRPF38B"	"hsa:55119; Q05DD6; Q32Q58; Q5VTL8; Q5VTL9; Q6PK39; Q7Z6E2; Q86WF3; Q8IWG9; Q9NW40"	""	""	"0"	"0"	"280.2"	"65.7"	"152.7"	"126.2"	"167.1"	"171.8"	"147.6"	"213.0"	"167.4"	"360.3"	"604.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BVG4"	"Protein PBDC1 OS=Homo sapiens OX=9606 GN=PBDC1 PE=1 SV=1"	"0.000"	""	"9"	"2"	"4"	"2"	"233"	"26.0"	"4.79"	"675.84"	"5.52"	"2"	"2"	""	""	""	"Pf04669"	"51260"	"ENSG00000102390"	"PBDC1"	"hsa:51260; Q9BVG4"	""	""	"0"	"0"	"94.2"	"41.9"	"82.0"	"58.6"	"86.7"	"91.7"	"70.7"	"81.9"	"71.1"	"147.1"	"281.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P21579"	"Synaptotagmin-1 OS=Homo sapiens OX=9606 GN=SYT1 PE=1 SV=1"	"0.000"	""	"5"	"2"	"4"	"2"	"422"	"47.5"	"8.12"	"645.76"	"5.49"	"2"	"2"	"cell-cell signaling;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00168"	"6857"	"ENSG00000067715"	"SYT1"	"hsa:6857; P21579; Q6AI31"	"Cargo recognition for clathrin-mediated endocytosis; Glutamate Neurotransmitter Release Cycle; Neurexins and neuroligins; Serotonin Neurotransmitter Release Cycle; Norepinephrine Neurotransmitter Release Cycle; Dopamine Neurotransmitter Release Cycle; Acetylcholine Neurotransmitter Release Cycle; GABA synthesis, release, reuptake and degradation; Toxicity of botulinum toxin type B (botB); Toxicity of botulinum toxin type G (botG)"	"Synaptic vesicle pathway"	"12"	"0"	"52.2"	"21.8"	"49.5"	"36.4"	"43.6"	"49.1"	"43.9"	"76.1"	"115.4"	"461.1"	"556.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P20585"	"DNA mismatch repair protein Msh3 OS=Homo sapiens OX=9606 GN=MSH3 PE=1 SV=4"	"0.000"	""	"4"	"3"	"4"	"3"	"1137"	"127.3"	"8.02"	"509.30"	"5.47"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00488, Pf01624, Pf05188, Pf05192"	"4437"	"ENSG00000113318"	"MSH3"	"A1L480; A1L482; A6NMM6; hsa:4437; P20585; Q6PJT5; Q86UQ6; Q92867"	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta); Defective Mismatch Repair Associated With MSH3; Defective Mismatch Repair Associated With MSH2"	"Chromosomal and microsatellite instability in colorectal cancer ; DNA repair pathways, full network"	"5"	"0"	"7.8"	"4.3"	"5.9"	"5.7"	"8.1"	"7.8"	"5.3"	"15.2"	"9.3"	"17.9"	"36.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKF6"	"Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1"	"0.000"	""	"2"	"2"	"4"	"2"	"684"	"77.4"	"5.60"	"647.48"	"5.47"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00753, Pf07521, Pf10996, Pf11718"	"51692"	"ENSG00000119203"	"CPSF3"	"hsa:51692; O14769; Q53RS2; Q96F36; Q9UKF6"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; Transport of Mature mRNA Derived from an Intronless Transcript"	"mRNA processing"	"6"	"0"	"438.1"	"166.7"	"378.1"	"327.6"	"374.6"	"418.1"	"302.4"	"374.0"	"263.1"	"569.7"	"1079.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15434"	"RNA-binding motif, single-stranded-interacting protein 2 OS=Homo sapiens OX=9606 GN=RBMS2 PE=1 SV=1"	"0.000"	""	"4"	"2"	"3"	"2"	"407"	"43.9"	"9.07"	"303.09"	"5.47"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"5939"	"ENSG00000076067"	"RBMS2"	"hsa:5939; Q15434"	""	""	"0"	"0"	"67.3"	"27.7"	"60.7"	"59.1"	"53.1"	"67.9"	"48.8"	"54.2"	"40.3"	"69.7"	"79.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61026"	"Ras-related protein Rab-10 OS=Homo sapiens OX=9606 GN=RAB10 PE=1 SV=1"	"0.000"	""	"12"	"2"	"4"	"1"	"200"	"22.5"	"8.38"	"812.96"	"5.47"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00071"	"10890"	"ENSG00000084733"	"RAB10"	"D6W538; hsa:10890; O88386; P61026; Q6IA52; Q9D7X6; Q9H0T3"	"Neutrophil degranulation; RAB GEFs exchange GTP for GDP on RABs; Translocation of SLC2A4 (GLUT4) to the plasma membrane; RAB geranylgeranylation"	"Focal adhesion: PI3K-Akt-mTOR-signaling pathway"	"5"	"0"	"16.7"	"6.5"	"13.0"	"7.3"	"10.3"	"7.8"	"13.9"	"12.2"	"8.8"	"15.8"	"37.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14008"	"Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3"	"0.000"	""	"1"	"2"	"3"	"2"	"2032"	"225.4"	"7.80"	"340.58"	"5.47"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02985, Pf12348"	"9793"	"ENSG00000175216"	"CKAP5"	"hsa:9793; Q05D70; Q0VAX7; Q0VAX8; Q14008; Q14668; Q2TA89; Q6NSH4"	"Separation of Sister Chromatids; Regulation of PLK1 Activity at G2/M Transition; RHO GTPases Activate Formins; Resolution of Sister Chromatid Cohesion; Recruitment of NuMA to mitotic centrosomes; EML4 and NUDC in mitotic spindle formation; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"4p16.3 copy number variation"	"14"	"0"	"171.0"	"64.6"	"153.6"	"115.5"	"130.6"	"166.3"	"127.5"	"162.9"	"115.0"	"230.6"	"496.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96T88"	"E3 ubiquitin-protein ligase UHRF1 OS=Homo sapiens OX=9606 GN=UHRF1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"793"	"89.8"	"7.56"	"611.33"	"5.45"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00240, Pf00628, Pf02182, Pf12148"	"29128"	"ENSG00000276043"	"UHRF1"	"A0JBR2; A8K024; B2RBA9; hsa:29128; Q2HIX7; Q8J022; Q96T88; Q9H6S6; Q9P115; Q9P1U7"	"DNA methylation"	"Pathways affected in adenoid cystic carcinoma; Pleural mesothelioma"	"3"	"0"	"24.5"	"6.8"	"14.4"	"17.6"	"12.6"	"12.6"	"15.1"	"20.8"	"10.9"	"32.7"	"51.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15910"	"Histone-lysine N-methyltransferase EZH2 OS=Homo sapiens OX=9606 GN=EZH2 PE=1 SV=2"	"0.000"	""	"2"	"2"	"3"	"2"	"746"	"85.3"	"7.02"	"363.33"	"5.45"	"1"	"2"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00856, Pf11616, Pf18118, Pf18264"	"2146"	"ENSG00000106462"	"EZH2"	"B2RAQ1; B3KS30; B7Z1D6; B7Z7L6; hsa:2146; Q15755; Q15910; Q75MG3; Q92857; Q96FI6"	"HCMV Early Events; Oxidative Stress Induced Senescence; Activation of anterior HOX genes in hindbrain development during early embryogenesis; PRC2 methylates histones and DNA; Defective pyroptosis; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6; PKMTs methylate histone lysines"	"Cell differentiation - expanded index; Histone modifications; Endoderm differentiation; Interactome of polycomb repressive complex 2 (PRC2) ; MECP2 and associated Rett syndrome; Tumor suppressor activity of SMARCB1; Epithelial to mesenchymal transition in colorectal cancer; lncRNA in canonical Wnt signaling and colorectal cancer; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; Pleural mesothelioma"	"19"	"0"	"102.5"	"44.5"	"106.7"	"95.9"	"94.9"	"124.3"	"97.7"	"152.4"	"107.1"	"195.9"	"356.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86T24"	"Transcriptional regulator Kaiso OS=Homo sapiens OX=9606 GN=ZBTB33 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"672"	"74.4"	"5.12"	"497.09"	"5.44"	"1"	"1"	"cell-cell signaling;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00651"	"10009"	"ENSG00000177485"	"ZBTB33"	"B2R5U6; hsa:10009; O00319; Q7Z361; Q86T24; Q8IVP6; Q8N3P0"	""	"Wnt signaling pathway and pluripotency"	"1"	"0"	"37.5"	"16.6"	"39.8"	"32.5"	"34.1"	"45.1"	"31.1"	"37.7"	"27.7"	"47.5"	"72.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQ67"	"Glutamate-rich WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=GRWD1 PE=1 SV=1"	"0.000"	""	"6"	"2"	"4"	"2"	"446"	"49.4"	"4.92"	"520.29"	"5.44"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400, Pf12265"	"83743"	"ENSG00000105447"	"GRWD1"	"A0MNN5; hsa:83743; Q8TF59; Q9BQ67"	""	""	"0"	"0"	"135.2"	"64.2"	"116.0"	"97.0"	"111.5"	"130.8"	"110.0"	"131.9"	"108.6"	"233.2"	"401.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q08426"	"Peroxisomal bifunctional enzyme OS=Homo sapiens OX=9606 GN=EHHADH PE=1 SV=3"	"0.000"	""	"4"	"2"	"3"	"2"	"723"	"79.4"	"9.14"	"307.80"	"5.43"	"1"	"2"	"other metabolic processes"	"cytosol;other cytoplasmic organelle"	"other molecular function"	"Pf00378, Pf00725, Pf02737"	"1962"	"ENSG00000113790"	"EHHADH"	"A8K6Y3; B4DWG3; D3DNU0; hsa:1962; Q08426; Q58EZ5"	"Peroxisomal protein import; Beta-oxidation of very long chain fatty acids"	"Constitutive androstane receptor pathway; PPAR-alpha pathway; Nuclear receptors meta-pathway; Mitochondrial long chain fatty acid beta-oxidation; Valproic acid pathway; Amino acid metabolism; PPAR signaling pathway; Eicosanoid metabolism via cyclooxygenases (COX); Eicosanoid metabolism via lipooxygenases (LOX); Mitochondrial fatty acid oxidation disorders"	"12"	"0"	"23.7"	"9.4"	"22.1"	"20.0"	"17.1"	"25.4"	"15.5"	"23.0"	"12.3"	"50.8"	"145.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P36957"	"Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLST PE=1 SV=4"	"0.000"	""	"4"	"2"	"4"	"2"	"453"	"48.7"	"8.95"	"638.06"	"5.43"	"2"	"2"	"protein metabolism;other metabolic processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00198, Pf00364"	"1743"	"ENSG00000119689"	"DLST"	"B7Z5W8; E7ESY5; hsa:1743; P36957; Q7LDY7; Q9BQ32"	"Citric acid cycle (TCA cycle); Lysine catabolism; Glyoxylate metabolism and glycine degradation"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Metabolic reprogramming in colon cancer; 7q11.23 copy number variation syndrome; 1p36 copy number variation syndrome; 10q11.21q11.23 copy number variation syndrome; TCA cycle (aka Krebs or citric acid cycle)"	"10"	"0"	"195.1"	"73.3"	"136.2"	"117.8"	"142.0"	"147.3"	"128.9"	"163.8"	"176.1"	"232.1"	"342.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43242"	"26S proteasome non-ATPase regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PSMD3 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"534"	"60.9"	"8.44"	"432.87"	"5.42"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf01399, Pf08375"	"5709"	"ENSG00000108344"	"PSMD3"	"B3KMW9; B4DT72; hsa:5709; O43242; Q96EI2; Q9BQA4"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"64"	"0"	"53.9"	"22.8"	"51.1"	"48.0"	"50.6"	"61.9"	"37.9"	"49.1"	"37.9"	"68.7"	"121.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30048"	"Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3"	"0.000"	""	"8"	"2"	"4"	"2"	"256"	"27.7"	"7.78"	"616.92"	"5.41"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00578, Pf10417"	"10935"	"ENSG00000165672"	"PRDX3"	"B2R7Z0; D3DRC9; E9PH29; hsa:10935; P30048; P35690; Q0D2H1; Q13776; Q5T5V2; Q96HK4"	"Detoxification of Reactive Oxygen Species"	"Selenium micronutrient network"	"2"	"0"	"222.8"	"61.8"	"122.3"	"98.6"	"154.0"	"152.7"	"135.0"	"190.8"	"183.8"	"552.9"	"730.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96RN5"	"Mediator of RNA polymerase II transcription subunit 15 OS=Homo sapiens OX=9606 GN=MED15 PE=1 SV=2"	"0.000"	""	"2"	"1"	"4"	"1"	"788"	"86.7"	"9.42"	"608.84"	"5.39"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf09606"	"51586"	"ENSG00000099917"	"MED15"	"D3DX31; D3DX32; hsa:51586; O15413; Q6IC31; Q8NF16; Q96CT0; Q96IH7; Q96RN5; Q9P1T3"	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; Generic Transcription Pathway"	"Sterol regulatory element-binding proteins (SREBP) signaling; SREBF and miR33 in cholesterol and lipid homeostasis; 22q11.2 copy number variation syndrome"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q5TBB1"	"Ribonuclease H2 subunit B OS=Homo sapiens OX=9606 GN=RNASEH2B PE=1 SV=1"	""	""	"6"	"2"	"2"	"2"	"312"	"35.1"	"9.13"	""	"5.39"	""	"2"	"cell cycle OR cell proliferation;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	""	"Pf09468, Pf17745"	"79621"	"ENSG00000136104"	"RNASEH2B"	"G3XAJ1; hsa:79621; Q05DR2; Q5TBB1; Q6PK48; Q9HAF7"	""	""	"0"	"0"	"112.7"	"40.7"	"93.0"	"83.1"	"101.8"	"103.6"	"75.8"	"105.5"	"77.9"	"246.7"	"640.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TAT6"	"Nuclear protein localization protein 4 homolog OS=Homo sapiens OX=9606 GN=NPLOC4 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"608"	"68.1"	"6.38"	"541.47"	"5.39"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf05020, Pf05021, Pf11543"	"55666"	"ENSG00000182446"	"NPLOC4"	"hsa:55666; Q8N3J1; Q8TAT6; Q9H8V2; Q9H964; Q9NWR5; Q9P229"	"Neddylation; KEAP1-NFE2L2 pathway; Translesion Synthesis by POLH"	""	"3"	"0"	"83.6"	"28.6"	"70.2"	"44.6"	"58.7"	"79.5"	"56.8"	"75.0"	"52.6"	"109.7"	"226.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q00013"	"55 kDa erythrocyte membrane protein OS=Homo sapiens OX=9606 GN=MPP1 PE=1 SV=2"	"0.000"	""	"6"	"3"	"5"	"3"	"466"	"52.3"	"7.37"	"809.10"	"5.38"	"2"	"2"	"other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;kinase activity"	"Pf00018, Pf00595, Pf00625"	"4354"	"ENSG00000130830"	"MPP1"	"B4DZV5; G3XAI1; hsa:4354; Q00013; Q2TSB6; Q5J7V5"	"Sensory processing of sound by outer hair cells of the cochlea"	"MECP2 and associated Rett syndrome"	"2"	"0"	"119.3"	"49.3"	"97.3"	"68.7"	"110.3"	"130.7"	"96.2"	"117.5"	"128.6"	"210.5"	"345.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q06787"	"Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1"	"0.000"	""	"3"	"2"	"4"	"1"	"632"	"71.1"	"7.42"	"537.44"	"5.36"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"cytoskeletal activity;translation activity;nucleic acid binding activity;other molecular function"	"Pf00013, Pf05641, Pf12235, Pf16098, Pf17904, Pf18336"	"2332"	"ENSG00000102081"	"FMR1"	"A6NNH4; D3DWT0; D3DWT1; D3DWT2; G8JL90; hsa:2332; Q06787; Q16578; Q5PQZ6; Q99054"	""	"Ovarian infertility; Serotonin and anxiety; Prader-Willi and Angelman syndrome; Fragile X syndrome; Disruption of postsynaptic signaling by CNV; 15q11.2 copy number variation syndrome; Primary ovarian insufficiency"	"7"	"1"	"356.4"	"180.0"	"305.5"	"245.9"	"310.7"	"340.9"	"255.8"	"344.1"	"301.1"	"513.1"	"739.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P48739"	"Phosphatidylinositol transfer protein beta isoform OS=Homo sapiens OX=9606 GN=PITPNB PE=1 SV=2"	"0.000"	""	"8"	"2"	"4"	"2"	"271"	"31.5"	"6.87"	"581.11"	"5.36"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;ER/Golgi;other cell component"	"transporter activity;other molecular function"	"Pf02121"	"23760"	"ENSG00000180957"	"PITPNB"	"B3KYB8; B7Z7Q0; hsa:23760; P48739; Q8N5W1"	"PI and PC transport between ER and Golgi membranes"	""	"1"	"0"	"127.8"	"80.9"	"115.3"	"107.4"	"105.7"	"103.4"	"108.6"	"127.7"	"133.4"	"234.6"	"373.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L4I2"	"Arginine/serine-rich coiled-coil protein 2 OS=Homo sapiens OX=9606 GN=RSRC2 PE=1 SV=1"	"0.000"	""	"5"	"3"	"5"	"3"	"434"	"50.5"	"11.33"	"907.49"	"5.36"	"3"	"2"	""	""	""	"Pf15477"	"65117"	"ENSG00000111011"	"RSRC2"	"hsa:65117; Q6N040; Q6NW16; Q7L4I2; Q9H864"	""	""	"0"	"0"	"417.7"	"161.4"	"401.5"	"367.5"	"414.9"	"480.6"	"308.8"	"423.3"	"278.8"	"549.7"	"810.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5T653"	"39S ribosomal protein L2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL2 PE=1 SV=2"	"0.000"	""	"9"	"2"	"4"	"2"	"305"	"33.3"	"11.30"	"747.73"	"5.32"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf00181, Pf03947"	"51069"	"ENSG00000112651"	"MRPL2"	"B2RC56; hsa:51069; Q5T653; Q8WUL1; Q96Q56; Q9Y311"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"25.6"	"8.4"	"25.8"	"16.4"	"18.7"	"18.8"	"15.6"	"19.3"	"18.3"	"29.4"	"51.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52815"	"39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2"	"0.000"	""	"7"	"1"	"4"	"1"	"198"	"21.3"	"8.87"	"503.50"	"5.32"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00542, Pf16320"	"6182"	"ENSG00000262814"	"MRPL12"	"hsa:6182; P52815; Q969U0; Q9HCA2; Q9UQJ3"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"88.4"	"40.9"	"74.0"	"53.3"	"69.0"	"64.6"	"47.6"	"69.6"	"64.4"	"113.7"	"221.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UK61"	"Protein TASOR OS=Homo sapiens OX=9606 GN=TASOR PE=1 SV=3"	"0.000"	""	"1"	"2"	"4"	"2"	"1670"	"188.9"	"5.80"	"627.77"	"5.32"	"2"	"2"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf12509"	"23272"	"ENSG00000163946"	"TASOR"	"A1L3A4; B5ME28; hsa:23272; Q9H2F7; Q9UK61; Q9UPP7"	""	""	"0"	"0"	"123.6"	"54.8"	"93.2"	"82.4"	"88.5"	"94.1"	"77.4"	"95.6"	"93.7"	"169.7"	"321.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H7B2"	"Ribosome production factor 2 homolog OS=Homo sapiens OX=9606 GN=RPF2 PE=1 SV=2"	"0.000"	""	"6"	"1"	"2"	"1"	"306"	"35.6"	"9.99"	"557.06"	"5.31"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf04427"	"84154"	"ENSG00000197498"	"RPF2"	"hsa:84154; Q5VXN1; Q8N4A1; Q9H7B2"	""	""	"0"	"0"	"61.0"	"19.2"	"59.3"	"57.9"	"62.5"	"68.6"	"48.9"	"65.6"	"37.9"	"74.1"	"110.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q6P5R6"	"60S ribosomal protein L22-like 1 OS=Homo sapiens OX=9606 GN=RPL22L1 PE=1 SV=2"	""	""	"20"	"1"	"1"	"1"	"122"	"14.6"	"9.38"	""	"5.31"	""	"1"	"protein metabolism;other metabolic processes"	"translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01776"	"200916"	"ENSG00000163584"	"RPL22L1"	"hsa:200916; Q32Q77; Q6P5R6"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	""	"13"	"0"	"16.8"	"9.2"	"16.3"	"14.8"	"21.1"	"23.8"	"14.3"	"28.0"	"22.4"	"73.9"	"117.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P20073"	"Annexin A7 OS=Homo sapiens OX=9606 GN=ANXA7 PE=1 SV=3"	"0.000"	""	"2"	"1"	"4"	"1"	"488"	"52.7"	"5.68"	"635.58"	"5.30"	"1"	"1"	"other metabolic processes;other biological processes"	"other membranes;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00191"	"310"	"ENSG00000138279"	"ANXA7"	"hsa:310; P20073; Q5F2H3; Q5T0M6; Q5T0M7"	""	""	"0"	"0"	"329.4"	"196.5"	"243.2"	"266.6"	"289.4"	"324.6"	"323.2"	"373.6"	"352.2"	"521.9"	"1087.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35998"	"26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3"	"0.000"	""	"7"	"3"	"5"	"3"	"433"	"48.6"	"5.95"	"990.92"	"5.28"	"3"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf17862"	"5701"	"ENSG00000161057"	"PSMC2"	"A4D0Q1; B7Z5E2; hsa:5701; P35998; Q3LIA5; Q9UDI3"	"Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Neutrophil degranulation; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; ABC-family proteins mediated transport; Defective CFTR causes cystic fibrosis; UCH proteinases; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; MAPK6/MAPK4 signaling; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"64"	"0"	"85.6"	"31.9"	"77.3"	"60.3"	"90.9"	"88.4"	"59.0"	"81.4"	"61.7"	"119.5"	"192.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9ULU4"	"Protein kinase C-binding protein 1 OS=Homo sapiens OX=9606 GN=ZMYND8 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"1186"	"131.6"	"7.20"	""	"5.28"	""	"1"	"cell organization and biogenesis;DNA metabolism;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00439, Pf00855, Pf12064"	"23613"	"ENSG00000101040"	"ZMYND8"	"B3KVL2; B7Z2A8; B7Z3E0; B7Z680; B7ZM62; E1P5U5; F5H0X3; H7C0U2; hsa:23613; J3KPU3; Q13517; Q2HXV1; Q2HXV2; Q2HXV3; Q2HXV4; Q2HXV7; Q2HXV8; Q2HXV9; Q2HXW0; Q2HXW1; Q2HXW2; Q4JJ94; Q4JJ95; Q5TH09; Q5TH11; Q6MZM1; Q8WXC5; Q9H1F3; Q9H1F4; Q9H1F5; Q9H1L8; Q9H1L9; Q9H2G5; Q9NYN3; Q9UIX6; Q9ULU4"	""	""	"0"	"0"	"19.3"	"7.9"	"13.1"	"9.5"	"12.3"	"12.2"	"9.5"	"22.3"	"12.7"	"18.9"	"32.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12767"	"Transmembrane protein 94 OS=Homo sapiens OX=9606 GN=TMEM94 PE=1 SV=1"	"0.000"	""	"1"	"2"	"4"	"2"	"1356"	"151.1"	"6.44"	"599.83"	"5.28"	"2"	"2"	""	"other membranes"	""	""	"9772"	"ENSG00000177728"	"TMEM94"	"C9JL75; hsa:9772; O75536; Q12767; Q86XF1"	""	""	"0"	"0"	"44.3"	"18.9"	"26.5"	"28.5"	"34.0"	"64.8"	"131.6"	"364.0"	"430.2"	"1016.8"	"1575.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N3I7"	"Bardet-Biedl syndrome 5 protein OS=Homo sapiens OX=9606 GN=BBS5 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"341"	"38.7"	"5.60"	"579.95"	"5.26"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf07289"	"129880"	"ENSG00000163093"	"BBS5"	"D3DPC3; hsa:129880; Q6PKN0; Q8N3I7"	"BBSome-mediated cargo-targeting to cilium"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies; Bardet-Biedl syndrome"	"6"	"0"	"13.9"	"11.3"	"15.8"	"11.8"	"14.7"	"24.2"	"16.3"	"26.8"	"32.1"	"91.7"	"188.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62487"	"DNA-directed RNA polymerase II subunit RPB7 OS=Homo sapiens OX=9606 GN=POLR2G PE=1 SV=1"	"0.000"	""	"11"	"2"	"3"	"2"	"172"	"19.3"	"5.54"	"333.36"	"5.25"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00575, Pf03876"	"5436"	"ENSG00000168002"	"POLR2G"	"B2R5C0; hsa:5436; P52433; P62487; Q2M1Z4"	"Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; mRNA Splicing - Major Pathway; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"Pyrimidine metabolism; Eukaryotic transcription initiation"	"43"	"0"	"177.5"	"72.3"	"142.3"	"117.1"	"155.0"	"185.6"	"160.5"	"219.3"	"171.7"	"290.6"	"516.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94776"	"Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1"	"0.000"	""	"3"	"2"	"4"	"2"	"668"	"75.0"	"9.66"	"566.43"	"5.24"	"2"	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00320, Pf01426, Pf01448, Pf17226"	"9219"	"ENSG00000149480"	"MTA2"	"hsa:9219; O94776; Q68DB1; Q9UQB5"	"Potential therapeutics for SARS; Regulation of PTEN gene transcription; HDACs deacetylate histones; RNA Polymerase I Transcription Initiation; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of TP53 Activity through Acetylation"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"7"	"0"	"113.0"	"47.5"	"99.4"	"86.3"	"97.6"	"119.1"	"91.8"	"121.3"	"86.1"	"208.4"	"282.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96Q89"	"Kinesin-like protein KIF20B OS=Homo sapiens OX=9606 GN=KIF20B PE=1 SV=3"	"0.000"	""	"1"	"2"	"4"	"2"	"1820"	"210.5"	"5.67"	"485.48"	"5.24"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225"	"9585"	"ENSG00000138182"	"KIF20B"	"A8MXM7; hsa:9585; O43277; Q09471; Q2KQ73; Q32NE1; Q561V3; Q58EX8; Q5T9M8; Q5T9M9; Q5T9N0; Q5T9N1; Q7KZ68; Q7Z5E0; Q7Z5E1; Q7Z6M9; Q86X82; Q96Q89; Q9H3R8; Q9H6Q9; Q9H755; Q9NTC1; Q9UFR5"	"COPI-dependent Golgi-to-ER retrograde traffic; Kinesins"	"Gastric cancer network 1"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NEY8"	"Periphilin-1 OS=Homo sapiens OX=9606 GN=PPHLN1 PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"458"	"52.7"	"9.11"	"315.18"	"5.23"	"1"	"2"	"cell organization and biogenesis;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	""	"Pf11488"	"51535"	"ENSG00000134283"	"PPHLN1"	"E9PAX8; hsa:51535; Q86YT2; Q8IXN3; Q8NEY8; Q8TB09; Q96NB9; Q9NXL4; Q9P0P6; Q9P0R9"	""	""	"0"	"0"	"607.1"	"191.1"	"396.7"	"325.0"	"417.8"	"416.0"	"311.3"	"435.8"	"324.6"	"798.0"	"1774.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5J9"	"Mitochondrial import inner membrane translocase subunit Tim8 B OS=Homo sapiens OX=9606 GN=TIMM8B PE=1 SV=1"	"0.000"	""	"18"	"2"	"3"	"2"	"83"	"9.3"	"5.12"	"308.21"	"5.22"	"1"	"2"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf02953"	"26521"	"ENSG00000150779"	"TIMM8B"	"B0YJA5; hsa:26521; Q3KQS9; Q9UN04; Q9Y5J9"	"Mitochondrial protein import"	""	"1"	"0"	"273.2"	"171.9"	"236.5"	"232.0"	"246.7"	"294.6"	"236.2"	"283.9"	"287.0"	"382.4"	"512.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P23378"	"Glycine dehydrogenase (decarboxylating), mitochondrial OS=Homo sapiens OX=9606 GN=GLDC PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1020"	"112.7"	"7.11"	""	"5.18"	""	"1"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01212, Pf02347"	"2731"	"ENSG00000178445"	"GLDC"	"hsa:2731; P23378; Q2M2F8"	"Glycine degradation"	"Metabolic Epileptic Disorders"	"2"	"0"	"34.7"	"21.9"	"34.2"	"25.3"	"32.4"	"36.1"	"29.8"	"37.5"	"35.9"	"203.6"	"733.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30533"	"Alpha-2-macroglobulin receptor-associated protein OS=Homo sapiens OX=9606 GN=LRPAP1 PE=1 SV=1"	"0.000"	""	"7"	"2"	"4"	"2"	"357"	"41.4"	"8.78"	"538.99"	"5.18"	"2"	"2"	"transport;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf06400, Pf06401"	"4043"	"ENSG00000163956"	"LRPAP1"	"D3DVR9; hsa:4043; P30533; Q2M310; Q53HQ3; Q53HS6"	""	"Cholesterol metabolism"	"1"	"0"	"93.5"	"51.4"	"79.4"	"75.7"	"62.2"	"87.4"	"84.1"	"112.8"	"135.8"	"500.5"	"772.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86W92"	"Liprin-beta-1 OS=Homo sapiens OX=9606 GN=PPFIBP1 PE=1 SV=2"	"0.001"	""	"3"	"2"	"3"	"2"	"1011"	"114.0"	"5.55"	"238.80"	"5.17"	"1"	"2"	"cell adhesion;cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf00536, Pf07647"	"8496"	"ENSG00000110841"	"PPFIBP1"	"hsa:8496; O75336; Q86W92; Q86X70; Q9NY03; Q9ULJ0"	"Signaling by ALK fusions and activated point mutants; Receptor-type tyrosine-protein phosphatases"	""	"2"	"0"	"100.1"	"42.5"	"84.0"	"66.8"	"75.3"	"87.7"	"60.7"	"78.7"	"67.8"	"119.7"	"141.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N8S7"	"Protein enabled homolog OS=Homo sapiens OX=9606 GN=ENAH PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"591"	"66.5"	"6.93"	"583.82"	"5.14"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00568, Pf08776"	"55740"	"ENSG00000154380"	"ENAH"	"D0PQI2; hsa:55740; Q502W5; Q5T5M7; Q5VTQ9; Q5VTR0; Q8N8S7; Q9NVF3; Q9UFB8"	"Generation of second messenger molecules; Signaling by ROBO receptors"	"Regulation of actin cytoskeleton"	"3"	"0"	"199.4"	"47.4"	"179.7"	"159.5"	"204.3"	"215.2"	"131.9"	"162.7"	"93.2"	"246.8"	"411.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95239"	"Chromosome-associated kinesin KIF4A OS=Homo sapiens OX=9606 GN=KIF4A PE=1 SV=3"	"0.000"	""	"2"	"2"	"4"	"2"	"1232"	"139.8"	"6.27"	"493.88"	"5.13"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00225"	"24137"	"ENSG00000090889"	"KIF4A"	"B2R7V5; D3DVU4; hsa:24137; O95239; Q86TN3; Q86XX7; Q9NNY6; Q9NY24; Q9UMW3"	"Recycling pathway of L1; COPI-dependent Golgi-to-ER retrograde traffic; MHC class II antigen presentation; Kinesins"	"Retinoblastoma gene in cancer"	"5"	"0"	"5.4"	"2.0"	"5.6"	"4.6"	"10.0"	"7.9"	"5.2"	"6.4"	"6.5"	"15.2"	"45.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00186"	"Syntaxin-binding protein 3 OS=Homo sapiens OX=9606 GN=STXBP3 PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"592"	"67.7"	"7.80"	"366.86"	"5.12"	"1"	"2"	"cell adhesion;cell-cell signaling;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00995"	"6814"	"ENSG00000116266"	"STXBP3"	"A8K269; A8K5K7; hsa:6814; O00186; Q53FW1; Q86YJ3; Q9UPD7"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Disinhibition of SNARE formation"	"Insulin signaling"	"3"	"0"	"101.2"	"45.9"	"104.7"	"80.2"	"90.3"	"116.6"	"90.2"	"122.9"	"82.3"	"175.6"	"346.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96MG7"	"Non-structural maintenance of chromosomes element 3 homolog OS=Homo sapiens OX=9606 GN=NSMCE3 PE=1 SV=1"	"0.000"	""	"5"	"2"	"4"	"2"	"304"	"34.3"	"9.28"	"604.02"	"5.11"	"2"	"2"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf01454"	"56160"	"ENSG00000185115; ENSG00000282130"	"NSMCE3"	"hsa:56160; Q8IW16; Q8TEI6; Q96MG7; Q9H214"	"SUMOylation of DNA damage response and repair proteins"	"15q11q13 copy number variation"	"2"	"0"	"154.0"	"78.8"	"141.1"	"105.8"	"137.7"	"160.0"	"134.1"	"185.7"	"229.7"	"400.2"	"809.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O43709"	"Probable 18S rRNA (guanine-N(7))-methyltransferase OS=Homo sapiens OX=9606 GN=BUD23 PE=1 SV=2"	""	""	"10"	"1"	"1"	"1"	"281"	"31.9"	"8.73"	""	"5.09"	""	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf08241, Pf12589"	"114049"	"ENSG00000071462"	"BUD23"	"A8K501; C9K060; hsa:114049; O43709; Q96P12; Q9BQ58; Q9HBP9"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"7q11.23 copy number variation syndrome"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O00443"	"Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1686"	"190.6"	"8.02"	""	"5.08"	""	"1"	"cell organization and biogenesis;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00168, Pf00454, Pf00613, Pf00787, Pf00792, Pf00794"	"5286"	"ENSG00000011405"	"PIK3C2A"	"B0LPH2; B4E2G4; hsa:5286; O00443; Q14CQ9"	"Golgi Associated Vesicle Biogenesis; Clathrin-mediated endocytosis; Synthesis of PIPs at the plasma membrane; Synthesis of PIPs at the Golgi membrane; Synthesis of PIPs at the early endosome membrane; Synthesis of PIPs at the late endosome membrane"	"Glioblastoma signaling pathways; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Microglia pathogen phagocytosis pathway; Osteoblast differentiation and related diseases; Insulin signaling; Regulation of actin cytoskeleton; DNA damage response (only ATM dependent)"	"14"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WXC6"	"COP9 signalosome complex subunit 9 OS=Homo sapiens OX=9606 GN=COPS9 PE=1 SV=3"	"0.000"	""	"35"	"1"	"2"	"1"	"57"	"6.2"	"3.83"	"456.30"	"5.08"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	""	"Pf15004"	"150678"	"ENSG00000172428"	"COPS9"	"hsa:150678; Q8N110; Q8WXC6"	""	"2q37 copy number variation syndrome"	"1"	"0"	"8.7"	"4.3"	"10.7"	"8.6"	"8.8"	"9.1"	"9.1"	"16.6"	"13.7"	"27.2"	"67.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4E8"	"Ubiquitin carboxyl-terminal hydrolase 15 OS=Homo sapiens OX=9606 GN=USP15 PE=1 SV=3"	"0.000"	""	"2"	"2"	"4"	"2"	"981"	"112.3"	"5.22"	"548.36"	"5.08"	"2"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00443, Pf06337, Pf14533, Pf14836"	"9958"	"ENSG00000135655"	"USP15"	"hsa:9958; Q08AL5; Q9H8G9; Q9HCA6; Q9UNP0; Q9Y4E8; Q9Y5B5"	"Ub-specific processing proteases; UCH proteinases; Downregulation of TGF-beta receptor signaling"	""	"3"	"0"	"153.1"	"68.4"	"179.8"	"161.5"	"169.9"	"199.7"	"150.4"	"181.6"	"151.3"	"304.5"	"400.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75150"	"E3 ubiquitin-protein ligase BRE1B OS=Homo sapiens OX=9606 GN=RNF40 PE=1 SV=5"	"0.000"	""	"2"	"1"	"2"	"1"	"1001"	"113.6"	"6.29"	"479.56"	"5.07"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00097"	"9810"	"ENSG00000103549"	"RNF40"	"A0A024QZG0; hsa:9810; O75150; Q6AHZ6; Q6N005; Q7L3T6; Q8N615; Q96T18; Q9BSV9; Q9HC82"	"E3 ubiquitin ligases ubiquitinate target proteins"	"ATM signaling in development and disease"	"2"	"0"	"8.7"	"0.0"	"7.3"	"7.0"	"4.2"	"9.4"	"7.6"	"11.2"	"9.9"	"17.2"	"64.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61106"	"Ras-related protein Rab-14 OS=Homo sapiens OX=9606 GN=RAB14 PE=1 SV=4"	"0.000"	""	"10"	"2"	"3"	"1"	"215"	"23.9"	"6.21"	"361.60"	"5.06"	"1"	"2"	"cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00071"	"51552"	"ENSG00000119396"	"RAB14"	"B3KR31; hsa:51552; P35287; P61106; Q5JVD4; Q6Q7K5; Q969L0; Q9UI11"	"Neutrophil degranulation; RAB geranylgeranylation; RAB GEFs exchange GTP for GDP on RABs; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Synthesis of PIPs at the plasma membrane"	"Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Ciliary landscape"	"7"	"1"	"61.0"	"22.1"	"54.3"	"47.2"	"46.4"	"47.0"	"55.9"	"88.4"	"114.7"	"270.3"	"229.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P43490"	"Nicotinamide phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=NAMPT PE=1 SV=1"	"0.000"	""	"1"	"1"	"4"	"1"	"491"	"55.5"	"7.15"	"561.01"	"5.05"	"1"	"1"	"cell-cell signaling;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf04095, Pf18127"	"10135"	"ENSG00000105835"	"NAMPT"	"A4D0Q9; A4D0R0; hsa:10135; P43490; Q3KQV0; Q8WW95"	"NPAS4 regulates expression of target genes; BMAL1:CLOCK,NPAS2 activates circadian gene expression; Nicotinamide salvaging"	"Adipogenesis; NAD metabolism, sirtuins and aging; NAD+ metabolism; NAD+ biosynthetic pathways; Caloric restriction and aging; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence"	"9"	"0"	"133.9"	"52.3"	"128.1"	"97.7"	"132.9"	"157.6"	"100.0"	"136.5"	"104.3"	"247.5"	"497.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96T60"	"Bifunctional polynucleotide phosphatase/kinase OS=Homo sapiens OX=9606 GN=PNKP PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"521"	"57.0"	"8.46"	"448.73"	"5.05"	"1"	"1"	"DNA metabolism;other metabolic processes;stress response;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf08645, Pf13671, Pf17913"	"11284"	"ENSG00000039650"	"PNKP"	"hsa:11284; Q96T60; Q9BUL2; Q9P1V2; Q9UKU8; Q9UNF8; Q9UNI0"	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"	"Base excision repair; DNA repair pathways, full network"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18848"	"Cyclic AMP-dependent transcription factor ATF-4 OS=Homo sapiens OX=9606 GN=ATF4 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"351"	"38.6"	"4.96"	"468.15"	"5.04"	"1"	"1"	"cell-cell signaling;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00170"	"468"	"ENSG00000128272"	"ATF4"	"hsa:468; P18848; Q96AQ3; Q9UH31"	"NFE2L2 regulating anti-oxidant/detoxification enzymes; Response of EIF2AK1 (HRI) to heme deficiency; ATF4 activates genes in response to endoplasmic reticulum  stress; Response of EIF2AK4 (GCN2) to amino acid deficiency; ATF6 (ATF6-alpha) activates chaperone genes"	"Alzheimer's disease and miRNA effects; Myometrial relaxation and contraction pathways; Photodynamic therapy-induced unfolded protein response; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; mRNA, protein, and metabolite inducation pathway by cyclosporin A; PI3K-Akt signaling pathway; Nonalcoholic fatty liver disease; Joubert syndrome; Hepatitis B infection; Unfolded protein response; 7q11.23 copy number variation syndrome; Alzheimer's disease"	"20"	"0"	"103.2"	"41.1"	"129.2"	"102.5"	"114.3"	"128.5"	"82.9"	"144.9"	"99.5"	"210.3"	"316.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WW12"	"PEST proteolytic signal-containing nuclear protein OS=Homo sapiens OX=9606 GN=PCNP PE=1 SV=2"	"0.000"	""	"10"	"2"	"3"	"2"	"178"	"18.9"	"7.49"	"312.03"	"5.03"	"1"	"2"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes"	"nucleus"	""	"Pf15473"	"57092"	"ENSG00000081154"	"PCNP"	"B2RBE7; D3DN52; hsa:57092; Q53GF3; Q6AI44; Q8WW12; Q96CU3; Q9NS81"	""	""	"0"	"0"	"269.1"	"125.1"	"240.1"	"173.5"	"236.7"	"263.1"	"227.8"	"305.7"	"212.9"	"273.3"	"440.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96JM3"	"Chromosome alignment-maintaining phosphoprotein 1 OS=Homo sapiens OX=9606 GN=CHAMP1 PE=1 SV=2"	"0.000"	""	"4"	"3"	"4"	"3"	"812"	"89.0"	"8.44"	"797.82"	"5.02"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	""	"283489"	"ENSG00000198824"	"CHAMP1"	"B3KU06; hsa:283489; Q6P181; Q8NC88; Q96JM3; Q9BST0"	""	""	"0"	"0"	"108.3"	"42.1"	"83.0"	"82.6"	"103.7"	"112.0"	"105.0"	"149.8"	"89.9"	"148.0"	"266.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02543"	"60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2"	"0.000"	""	"10"	"2"	"3"	"2"	"176"	"20.7"	"10.71"	"337.70"	"5.02"	"1"	"2"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01775"	"6142"	"ENSG00000105640"	"RPL18A"	"hsa:6142; Q02543"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"15"	"0"	"320.8"	"117.2"	"301.6"	"295.3"	"277.4"	"339.6"	"234.1"	"329.8"	"200.5"	"413.0"	"654.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EV2"	"RNA-binding protein 33 OS=Homo sapiens OX=9606 GN=RBM33 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"1170"	"129.9"	"6.93"	"614.27"	"5.01"	"1"	"1"	""	""	""	""	"155435"	"ENSG00000184863"	"RBM33"	"A4D244; B5MC24; hsa:155435; Q52LF5; Q75LN9; Q75ML5; Q96EV2; Q9NSV0"	""	""	"0"	"0"	"79.8"	"42.7"	"68.9"	"68.7"	"84.1"	"87.6"	"61.5"	"80.7"	"63.8"	"110.9"	"144.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09622"	"Dihydrolipoyl dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=DLD PE=1 SV=2"	"0.000"	""	"4"	"2"	"4"	"2"	"509"	"54.1"	"7.85"	"517.63"	"5.00"	"2"	"2"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytoskeleton;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf02852, Pf07992"	"1738"	"ENSG00000091140"	"DLD"	"B2R5X0; B4DHG0; B4DT69; hsa:1738; P09622; Q14131; Q14167; Q59EV8; Q8WTS4"	"Lysine catabolism; Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid; Citric acid cycle (TCA cycle); Branched-chain amino acid catabolism; Glycine degradation"	"Fatty acid beta-oxidation; TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Tryptophan metabolism; 7q11.23 copy number variation syndrome; Neuroinflammation and glutamatergic signaling; Glycolysis and gluconeogenesis; 10q11.21q11.23 copy number variation syndrome; Metabolic Epileptic Disorders; TCA cycle (aka Krebs or citric acid cycle)"	"18"	"0"	"237.9"	"90.7"	"212.6"	"207.8"	"234.4"	"338.5"	"250.6"	"351.3"	"296.5"	"552.9"	"859.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14562"	"ATP-dependent RNA helicase DHX8 OS=Homo sapiens OX=9606 GN=DHX8 PE=1 SV=1"	"0.000"	""	"2"	"2"	"4"	"2"	"1220"	"139.2"	"8.32"	"560.16"	"5.00"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00271, Pf00575, Pf04408, Pf07717"	"1659"	"ENSG00000067596"	"DHX8"	"hsa:1659; Q14562"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"0"	"9.6"	"4.5"	"11.6"	"4.7"	"12.8"	"10.5"	"10.8"	"8.6"	"11.6"	"22.8"	"38.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8IXT5"	"RNA-binding protein 12B OS=Homo sapiens OX=9606 GN=RBM12B PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"1001"	"118.0"	"6.81"	""	"4.99"	""	"1"	"other biological processes"	"nucleus;other cell component"	""	"Pf00076"	"389677"	"ENSG00000183808"	"RBM12B"	"A8MYB5; hsa:389677; Q8IXT5"	""	""	"0"	"0"	"70.6"	"19.6"	"44.8"	"37.1"	"45.4"	"48.2"	"38.1"	"63.3"	"48.2"	"91.4"	"171.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NU22"	"Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2"	"0.000"	""	"0"	"2"	"4"	"2"	"5596"	"632.4"	"5.68"	"599.07"	"4.99"	"2"	"2"	"cell organization and biogenesis;transport"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07728, Pf17865, Pf17867"	"23195"	"ENSG00000112159; ENSG00000288121"	"MDN1"	"hsa:23195; O15019; Q5T794; Q9NU22"	""	""	"0"	"0"	"43.7"	"14.3"	"26.0"	"20.3"	"22.3"	"31.4"	"24.7"	"36.1"	"31.2"	"73.8"	"210.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H2H8"	"Peptidyl-prolyl cis-trans isomerase-like 3 OS=Homo sapiens OX=9606 GN=PPIL3 PE=1 SV=1"	"0.000"	""	"8"	"1"	"2"	"1"	"161"	"18.1"	"6.79"	"392.19"	"4.99"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00160"	"53938"	"ENSG00000240344"	"PPIL3"	"hsa:53938; Q86WF9; Q96IA9; Q9BXZ1; Q9H2H8"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"82.5"	"27.5"	"79.6"	"63.7"	"70.9"	"107.5"	"85.4"	"130.1"	"90.7"	"316.9"	"504.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKV8"	"Protein argonaute-2 OS=Homo sapiens OX=9606 GN=AGO2 PE=1 SV=3"	"0.000"	""	"3"	"2"	"3"	"2"	"859"	"97.1"	"9.19"	"336.70"	"4.98"	"1"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02170, Pf02171, Pf08699, Pf16486, Pf16487, Pf16488"	"27161"	"ENSG00000123908"	"AGO2"	"hsa:27161; Q8TCZ5; Q8WV58; Q96ID1; Q9UKV8"	"Transcriptional regulation by small RNAs; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; TP53 Regulates Metabolic Genes; Pre-NOTCH Transcription and Translation; Regulation of RUNX1 Expression and Activity; Small interfering RNA (siRNA) biogenesis; MAPK6/MAPK4 signaling; Ca2+ pathway; Regulation of MECP2 expression and activity; NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux; Regulation of CDH11 mRNA translation by microRNAs; Regulation of NPAS4 mRNA translation; Post-transcriptional silencing by small RNAs; Competing endogenous RNAs (ceRNAs) regulate PTEN translation"	"exRNA mechanism of action and biogenesis; Fragile X syndrome; Male infertility; Influence of laminopathies on Wnt signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies"	"22"	"0"	"36.5"	"24.2"	"42.3"	"32.7"	"36.5"	"42.3"	"35.3"	"46.4"	"45.2"	"87.0"	"128.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95989"	"Diphosphoinositol polyphosphate phosphohydrolase 1 OS=Homo sapiens OX=9606 GN=NUDT3 PE=1 SV=1"	"0.001"	""	"10"	"2"	"3"	"1"	"172"	"19.5"	"6.34"	"259.66"	"4.97"	"1"	"2"	"cell-cell signaling;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00293"	"11165"	"ENSG00000272325"	"NUDT3"	"B2R8N4; hsa:11165; O95989"	"Synthesis of pyrophosphates in the cytosol"	""	"1"	"0"	"16.2"	"10.5"	"24.9"	"70.0"	"44.6"	"204.8"	"253.1"	"334.8"	"213.2"	"492.0"	"1007.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49674"	"Casein kinase I isoform epsilon OS=Homo sapiens OX=9606 GN=CSNK1E PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"416"	"47.3"	"9.66"	"568.00"	"4.97"	"1"	"1"	"cell-cell signaling;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"102800317; 1454"	"ENSG00000213923"	"CSNK1E"	"hsa:102800317; hsa:1454; P49674"	"Major pathway of rRNA processing in the nucleolus and cytosol; WNT mediated activation of DVL; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Circadian Clock"	"Alzheimer's disease and miRNA effects; Melatonin metabolism and effects; Wnt signaling pathway; Wnt signaling pathway and pluripotency; Hedgehog signaling pathway; lncRNA in canonical Wnt signaling and colorectal cancer; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Pleural mesothelioma; Alzheimer's disease"	"20"	"0"	"59.0"	"10.6"	"41.9"	"44.2"	"36.7"	"64.8"	"31.7"	"52.8"	"45.4"	"181.0"	"302.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75874"	"Isocitrate dehydrogenase [NADP] cytoplasmic OS=Homo sapiens OX=9606 GN=IDH1 PE=1 SV=2"	"0.000"	""	"4"	"2"	"4"	"2"	"414"	"46.6"	"7.01"	"575.82"	"4.97"	"2"	"2"	"other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00180"	"3417"	"ENSG00000138413"	"IDH1"	"hsa:3417; O75874; Q567U4; Q6FHQ6; Q7Z3V0; Q93090; Q9NTJ9; Q9UKW8"	"Peroxisomal protein import; Neutrophil degranulation; Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate; NADPH regeneration; NFE2L2 regulating TCA cycle genes"	"Glutathione metabolism; TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism"	"8"	"0"	"223.7"	"90.4"	"182.7"	"124.7"	"158.0"	"186.2"	"146.1"	"178.4"	"162.9"	"292.0"	"421.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BYG3"	"MKI67 FHA domain-interacting nucleolar phosphoprotein OS=Homo sapiens OX=9606 GN=NIFK PE=1 SV=1"	"0.000"	""	"11"	"2"	"3"	"2"	"293"	"34.2"	"9.88"	"880.08"	"4.97"	"2"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf12196"	"84365"	"ENSG00000155438"	"NIFK"	"A8K788; hsa:84365; Q8TB66; Q96ED4; Q9BYG3"	""	""	"0"	"0"	"63.0"	"25.8"	"57.8"	"56.5"	"51.6"	"63.3"	"48.9"	"61.1"	"48.5"	"149.0"	"324.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q2TAA2"	"Isoamyl acetate-hydrolyzing esterase 1 homolog OS=Homo sapiens OX=9606 GN=IAH1 PE=1 SV=1"	"0.000"	""	"15"	"2"	"2"	"2"	"248"	"27.6"	"5.30"	"420.20"	"4.97"	"1"	"1"	"other metabolic processes"	""	"other molecular function"	"Pf13472"	"285148"	"ENSG00000134330"	"IAH1"	"B4DMV3; hsa:285148; Q2TAA2"	""	""	"0"	"0"	"13.7"	"11.3"	"25.2"	"31.6"	"18.0"	"30.7"	"20.7"	"25.2"	"9.6"	"16.9"	"26.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N122"	"Regulatory-associated protein of mTOR OS=Homo sapiens OX=9606 GN=RPTOR PE=1 SV=1"	"0.000"	""	"2"	"2"	"3"	"2"	"1335"	"148.9"	"6.89"	"298.19"	"4.95"	"1"	"2"	"cell organization and biogenesis;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00400, Pf02985, Pf14538"	"57521"	"ENSG00000141564"	"RPTOR"	"B2RN36; C6KEF2; F5H7J5; hsa:57521; Q8N122; Q8N4V9; Q8TB32; Q9P2P3"	"Regulation of PTEN gene transcription; TP53 Regulates Metabolic Genes; Amino acids regulate mTORC1; mTORC1-mediated signalling; Macroautophagy; Energy dependent regulation of mTOR by LKB1-AMPK; HSF1-dependent transactivation"	"AMP-activated protein kinase signaling; Target of rapamycin signaling; PI3K-AKT-mTOR signaling pathway and therapeutic opportunities in prostate cancer; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Clear cell renal cell carcinoma pathways; PI3K-Akt signaling pathway; Thermogenesis; Synaptic signaling pathways associated with autism spectrum disorder; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Head and neck squamous cell carcinoma; Thyroid hormones production and peripheral downstream signaling effects; IL-18 signaling pathway; CAMKK2 pathway; Autophagy; p53 transcriptional gene network; Pleural mesothelioma; Network map of SARS-CoV-2 signaling pathway; GDNF signaling; DYRK1A involvement regarding cell proliferation in brain development; JAK-STAT signaling in the regulation of Beta-cells; Interferon type I signaling pathways"	"33"	"0"	"78.1"	"56.7"	"59.2"	"56.9"	"55.9"	"54.7"	"71.4"	"81.8"	"76.9"	"130.0"	"197.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BU76"	"Multiple myeloma tumor-associated protein 2 OS=Homo sapiens OX=9606 GN=MMTAG2 PE=1 SV=1"	"0.000"	""	"10"	"2"	"3"	"2"	"263"	"29.4"	"10.02"	"961.04"	"4.95"	"2"	"1"	""	"non-structural extracellular;other cell component"	""	"Pf10159"	"79169"	"ENSG00000143793"	"MMTAG2"	"hsa:79169; Q6P5Y0; Q6ZTZ6; Q6ZWA6; Q8IZH3; Q9BU76"	"Neutrophil degranulation"	""	"1"	"0"	"172.1"	"64.5"	"125.4"	"114.2"	"125.4"	"151.1"	"116.0"	"149.2"	"115.4"	"322.6"	"605.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H0W8"	"Protein SMG9 OS=Homo sapiens OX=9606 GN=SMG9 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"520"	"57.6"	"7.01"	"634.72"	"4.94"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes"	"cytosol"	"other molecular function"	"Pf10220"	"56006"	"ENSG00000105771"	"SMG9"	"hsa:56006; O60429; Q9H0W8; Q9H9A9"	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	""	"1"	"0"	"19.9"	"7.2"	"16.8"	"14.9"	"16.2"	"12.9"	"13.1"	"15.1"	"10.8"	"18.6"	"25.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07919"	"Cytochrome b-c1 complex subunit 6, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRH PE=1 SV=2"	"0.000"	""	"14"	"2"	"5"	"2"	"91"	"10.7"	"4.44"	"744.16"	"4.94"	"2"	"2"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf02320"	"7388"	"ENSG00000173660"	"UQCRH"	"B2R4V9; D3DQ18; hsa:7388; P07919; Q5TDF6; Q6LDB8; Q9BQ91"	"Respiratory electron transport"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex III assembly"	"4"	"0"	"763.7"	"316.0"	"710.0"	"645.8"	"640.9"	"825.9"	"613.7"	"720.3"	"554.7"	"1063.2"	"1573.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P45880"	"Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2"	"0.000"	""	"6"	"2"	"4"	"2"	"294"	"31.5"	"7.56"	"579.76"	"4.93"	"2"	"2"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"other membranes;cytoskeleton;mitochondrion;other cell component"	"transporter activity;other molecular function"	"Pf01459"	"7417"	"ENSG00000165637"	"VDAC2"	"hsa:7417; P45880; Q5VWK1; Q5VWK3; Q6IB40; Q7L3J5; Q9BWK8; Q9Y5I6"	"Ub-specific processing proteases; Mitochondrial calcium ion transport"	"Alzheimer's disease and miRNA effects; Ferroptosis; Alzheimer's disease"	"5"	"0"	"223.4"	"55.6"	"93.8"	"59.0"	"107.1"	"100.8"	"119.7"	"141.2"	"160.2"	"239.7"	"627.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2W2"	"WW domain-binding protein 11 OS=Homo sapiens OX=9606 GN=WBP11 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"641"	"70.0"	"8.38"	"553.58"	"4.93"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09429"	"51729"	"ENSG00000084463"	"WBP11"	"hsa:51729; Q96AY8; Q9Y2W2"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"25.8"	"13.2"	"25.8"	"16.8"	"27.5"	"18.2"	"23.9"	"29.0"	"22.5"	"46.6"	"63.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96T58"	"Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1"	"0.001"	""	"1"	"2"	"3"	"2"	"3664"	"402.0"	"7.64"	"243.04"	"4.92"	"1"	"2"	"signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf07744"	"23013"	"ENSG00000065526"	"SPEN"	"hsa:23013; Q96T58; Q9H9A8; Q9NWH5; Q9UQ01; Q9Y556"	"RHOBTB1 GTPase cycle"	"Notch signaling pathway"	"2"	"0"	"128.5"	"66.2"	"141.8"	"119.1"	"113.6"	"126.7"	"106.6"	"149.5"	"110.7"	"234.2"	"477.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O43301"	"Heat shock 70 kDa protein 12A OS=Homo sapiens OX=9606 GN=HSPA12A PE=1 SV=2"	""	""	"4"	"2"	"2"	"2"	"675"	"74.9"	"6.77"	""	"4.92"	""	"2"	""	"nucleus;other cell component"	"other molecular function"	""	"259217"	"ENSG00000165868"	"HSPA12A"	"hsa:259217; O43301"	"Regulation of HSF1-mediated heat shock response"	""	"1"	"0"	"17.8"	"13.1"	"14.8"	"16.1"	"19.2"	"16.8"	"13.1"	"21.9"	"17.3"	"67.6"	"93.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UI10"	"Translation initiation factor eIF-2B subunit delta OS=Homo sapiens OX=9606 GN=EIF2B4 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"523"	"57.5"	"9.38"	"504.47"	"4.90"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01008"	"8890"	"ENSG00000115211"	"EIF2B4"	"hsa:8890; Q53RY7; Q5BJF4; Q9BUV9; Q9UBG4; Q9UI10; Q9UIQ9; Q9UJ95"	"Recycling of eIF2:GDP"	"Translation factors; Primary ovarian insufficiency"	"3"	"0"	"17.5"	"5.5"	"12.5"	"11.0"	"13.4"	"15.3"	"9.8"	"21.2"	"17.0"	"39.0"	"61.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6M9"	"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 OS=Homo sapiens OX=9606 GN=NDUFB9 PE=1 SV=3"	"0.000"	""	"12"	"2"	"3"	"2"	"179"	"21.8"	"8.38"	"823.50"	"4.89"	"2"	"1"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity"	"Pf05347"	"4715"	"ENSG00000147684"	"NDUFB9"	"B2R8M6; hsa:4715; Q9UQE8; Q9Y6M9"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial immune response to SARS-CoV-2; Oxidative phosphorylation"	"6"	"0"	"249.0"	"93.0"	"185.9"	"137.1"	"179.1"	"190.3"	"161.2"	"219.2"	"184.8"	"465.4"	"1065.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75446"	"Histone deacetylase complex subunit SAP30 OS=Homo sapiens OX=9606 GN=SAP30 PE=1 SV=1"	"0.000"	""	"5"	"1"	"4"	"1"	"220"	"23.3"	"9.17"	"503.21"	"4.88"	"1"	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13866, Pf13867"	"8819"	"ENSG00000164105"	"SAP30"	"D3DP38; hsa:8819; O75446"	"HDACs deacetylate histones; NoRC negatively regulates rRNA expression; Potential therapeutics for SARS"	"Retinoblastoma gene in cancer; Notch signaling pathway"	"5"	"0"	"26.0"	"12.3"	"17.2"	"19.1"	"16.7"	"24.7"	"19.2"	"23.3"	"23.9"	"45.4"	"76.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75909"	"Cyclin-K OS=Homo sapiens OX=9606 GN=CCNK PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"580"	"64.2"	"8.41"	"428.99"	"4.87"	"1"	"1"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00134"	"8812"	"ENSG00000090061"	"CCNK"	"hsa:8812; O75909; Q59FT6; Q86U16; Q96B63; Q9NNY9"	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes"	"Male infertility"	"10"	"0"	"59.9"	"17.2"	"52.9"	"36.5"	"47.4"	"41.0"	"38.7"	"50.2"	"38.2"	"89.2"	"224.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75718"	"Cartilage-associated protein OS=Homo sapiens OX=9606 GN=CRTAP PE=1 SV=1"	"0.000"	""	"4"	"2"	"4"	"2"	"401"	"46.5"	"5.73"	"543.41"	"4.87"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;ER/Golgi;other cell component"	""	""	"10491"	"ENSG00000170275"	"CRTAP"	"B2RBL6; hsa:10491; O75718"	"Collagen biosynthesis and modifying enzymes"	"Type I collagen synthesis in the context of osteogenesis imperfecta"	"2"	"0"	"337.6"	"157.4"	"259.1"	"203.9"	"253.7"	"275.3"	"202.2"	"260.3"	"223.1"	"417.9"	"744.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NRV9"	"Heme-binding protein 1 OS=Homo sapiens OX=9606 GN=HEBP1 PE=1 SV=1"	"0.000"	""	"15"	"2"	"3"	"2"	"189"	"21.1"	"5.80"	"394.09"	"4.84"	"1"	"2"	"other biological processes"	"non-structural extracellular;other cell component"	"other molecular function"	"Pf04832"	"50865"	"ENSG00000013583"	"HEBP1"	"A8K1G2; hsa:50865; Q9NRV9; Q9Y5Z5"	"G alpha (i) signalling events; Formyl peptide receptors bind formyl peptides and many other ligands"	""	"2"	"0"	"211.4"	"112.8"	"188.1"	"173.6"	"195.6"	"219.7"	"186.8"	"212.3"	"166.5"	"311.4"	"578.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N3E9"	"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 OS=Homo sapiens OX=9606 GN=PLCD3 PE=1 SV=3"	"0.001"	""	"4"	"2"	"2"	"2"	"789"	"89.2"	"6.98"	"254.42"	"4.83"	"1"	"1"	"other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	"other molecular function"	"Pf00168, Pf00387, Pf00388, Pf14788"	"113026"	"ENSG00000161714"	"PLCD3"	"hsa:113026; Q8N3E9; Q8TEC1; Q8TF37; Q96FL6"	"Synthesis of IP3 and IP4 in the cytosol"	"GPR40 pathway; Resistin as a regulator of inflammation"	"3"	"0"	"80.4"	"27.7"	"65.3"	"55.1"	"64.5"	"70.7"	"59.0"	"129.9"	"138.5"	"307.7"	"422.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4A5"	"Transformation/transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3"	"0.000"	""	"1"	"2"	"4"	"2"	"3859"	"437.3"	"8.19"	"607.77"	"4.82"	"2"	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00454, Pf02259, Pf20175, Pf20206"	"8295"	"ENSG00000196367"	"TRRAP"	"A4D265; hsa:8295; O75218; Q9Y4A5; Q9Y631; Q9Y6H4"	"Ub-specific processing proteases; Formation of the beta-catenin:TCF transactivating complex; HATs acetylate histones"	"Rett syndrome causing genes"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14156"	"Protein EFR3 homolog A OS=Homo sapiens OX=9606 GN=EFR3A PE=1 SV=2"	"0.001"	""	"3"	"2"	"3"	"2"	"821"	"92.9"	"6.70"	"263.02"	"4.80"	"1"	"2"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol"	""	""	"23167"	"ENSG00000132294"	"EFR3A"	"A7MD19; hsa:23167; Q14156; Q2VPK2; Q63HL7; Q68DX1; Q6IQ18"	""	""	"0"	"0"	"10.3"	"2.3"	"10.2"	"6.9"	"8.6"	"10.4"	"7.7"	"6.6"	"8.6"	"20.7"	"51.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52907"	"F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3"	"0.000"	""	"6"	"1"	"2"	"1"	"286"	"32.9"	"5.69"	"454.12"	"4.80"	"1"	"1"	"cell organization and biogenesis"	"non-structural extracellular;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf01267"	"829"	"ENSG00000116489"	"CAPZA1"	"hsa:829; P52907; Q53FQ6; Q6FHD5"	"MHC class II antigen presentation; COPI-mediated anterograde transport; Sensory processing of sound by inner hair cells of the cochlea; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-independent Golgi-to-ER retrograde traffic; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Factors involved in megakaryocyte development and platelet production; Advanced glycosylation endproduct receptor signaling"	""	"8"	"0"	"14.2"	"6.0"	"10.7"	"12.6"	"14.3"	"12.1"	"8.9"	"14.4"	"10.7"	"26.1"	"38.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15075"	"Early endosome antigen 1 OS=Homo sapiens OX=9606 GN=EEA1 PE=1 SV=2"	"0.000"	""	"3"	"3"	"4"	"3"	"1411"	"162.4"	"5.68"	"686.50"	"4.77"	"2"	"2"	"cell-cell signaling;cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01363"	"8411"	"ENSG00000102189"	"EEA1"	"hsa:8411; Q14221; Q15075"	"Toll Like Receptor 9 (TLR9) Cascade"	"VEGFA-VEGFR2 signaling"	"2"	"0"	"42.2"	"14.3"	"30.2"	"21.3"	"30.3"	"34.6"	"21.3"	"26.4"	"17.7"	"45.8"	"86.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P60981"	"Destrin OS=Homo sapiens OX=9606 GN=DSTN PE=1 SV=3"	"0.000"	""	"14"	"2"	"4"	"1"	"165"	"18.5"	"7.85"	"584.05"	"4.77"	"2"	"2"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00241"	"11034"	"ENSG00000125868"	"DSTN"	"B2R6N2; B4DYA6; hsa:11034; P18282; P60981; Q5W166; Q6IAW2"	""	"Androgen receptor signaling pathway"	"1"	"0"	"8.2"	"6.4"	"6.8"	"3.7"	"5.0"	"10.5"	"9.4"	"11.6"	"6.0"	"22.7"	"49.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NFH4"	"Nucleoporin Nup37 OS=Homo sapiens OX=9606 GN=NUP37 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"326"	"36.7"	"5.92"	"528.54"	"4.76"	"1"	"1"	"cell cycle OR cell proliferation;transport;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00400"	"79023"	"ENSG00000075188"	"NUP37"	"hsa:79023; Q8NFH4; Q9H644"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; ISG15 antiviral mechanism; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Vpr-mediated nuclear import of PICs; Transport of Mature mRNA derived from an Intron-Containing Transcript; HCMV Early Events; tRNA processing in the nucleus; HCMV Late Events; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); SARS-CoV-2 activates/modulates innate and adaptive immune responses; Postmitotic nuclear pore complex (NPC) reformation"	""	"35"	"0"	"25.8"	"10.1"	"26.8"	"25.0"	"28.4"	"26.4"	"14.0"	"25.8"	"19.7"	"43.2"	"67.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55010"	"Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2"	"0.001"	""	"3"	"1"	"3"	"1"	"431"	"49.2"	"5.58"	"272.32"	"4.75"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf01873, Pf02020"	"1983"	"ENSG00000100664"	"EIF5"	"hsa:1983; P55010; Q53XB3; Q9H5N2; Q9UG48"	"Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBE0"	"SUMO-activating enzyme subunit 1 OS=Homo sapiens OX=9606 GN=SAE1 PE=1 SV=1"	"0.000"	""	"5"	"2"	"3"	"2"	"346"	"38.4"	"5.30"	"314.56"	"4.75"	"1"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00899"	"10055"	"ENSG00000142230"	"SAE1"	"B2RDP5; B3KMQ2; F5GXX7; G3XAK6; hsa:10055; O95717; Q9P020; Q9UBE0"	"SUMO is conjugated to E1 (UBA2:SAE1); SUMO is transferred from E1 to E2 (UBE2I, UBC9)"	""	"2"	"0"	"82.2"	"26.8"	"50.6"	"35.6"	"67.5"	"69.1"	"64.4"	"55.3"	"72.2"	"90.4"	"154.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96RT1"	"Erbin OS=Homo sapiens OX=9606 GN=ERBIN PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"2"	"1412"	"158.2"	"5.50"	"496.82"	"4.73"	"2"	"2"	"cell adhesion;cell organization and biogenesis;transport;signal transduction;other biological processes"	"extracellular matrix;plasma membrane;other membranes;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity"	"Pf00595, Pf13855"	"55914"	"ENSG00000112851"	"ERBIN"	"A0AVR1; B4E3F1; B7ZLV9; E7EQW9; E9PCR8; hsa:55914; Q1RMD0; Q86W38; Q96RT1; Q9NR18; Q9NW48; Q9ULJ5"	"RHOG GTPase cycle; Downregulation of ERBB2 signaling; RHOC GTPase cycle; RHOA GTPase cycle; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOB GTPase cycle; Signaling by ERBB2 KD Mutants; Signaling by ERBB2 TMD/JMD mutants; Signaling by ERBB2 ECD mutants; Constitutive Signaling by Overexpressed ERBB2; Drug-mediated inhibition of ERBB2 signaling; Resistance of ERBB2 KD mutants to trastuzumab; Resistance of ERBB2 KD mutants to sapitinib; Resistance of ERBB2 KD mutants to tesevatinib; Resistance of ERBB2 KD mutants to neratinib; Resistance of ERBB2 KD mutants to osimertinib; Resistance of ERBB2 KD mutants to afatinib; Resistance of ERBB2 KD mutants to AEE788; Resistance of ERBB2 KD mutants to lapatinib; Drug resistance in ERBB2 TMD/JMD mutants"	"Nucleotide-binding oligomerization domain (NOD) pathway; Nod-like receptor (NLR) signaling pathway; Pathways affected in adenoid cystic carcinoma"	"26"	"0"	"12.4"	"3.9"	"9.9"	"10.2"	"16.1"	"13.4"	"10.7"	"18.8"	"14.2"	"18.6"	"47.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NP79"	"Vacuolar protein sorting-associated protein VTA1 homolog OS=Homo sapiens OX=9606 GN=VTA1 PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"307"	"33.9"	"6.29"	"492.62"	"4.73"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	""	"Pf04652, Pf18097"	"51534"	"ENSG00000009844"	"VTA1"	"B4DW55; E1P594; E7ETQ7; hsa:51534; Q5TGM1; Q6IAE8; Q9H0R2; Q9H3K9; Q9NP79; Q9P0Q0"	"Endosomal Sorting Complex Required For Transport (ESCRT); Budding and maturation of HIV virion"	""	"2"	"0"	"20.4"	"9.9"	"27.1"	"25.1"	"24.5"	"29.7"	"21.7"	"28.5"	"25.3"	"36.2"	"62.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96BZ8"	"Leukocyte receptor cluster member 1 OS=Homo sapiens OX=9606 GN=LENG1 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"264"	"30.5"	"9.69"	"530.31"	"4.72"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"34.8"	"25.4"	"31.5"	"24.2"	"28.2"	"33.7"	"31.3"	"43.4"	"34.2"	"75.9"	"113.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14923"	"Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3"	"0.000"	""	"6"	"4"	"5"	"3"	"745"	"81.7"	"6.14"	"870.82"	"4.70"	"3"	"2"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00514"	"3728"	"ENSG00000173801"	"JUP"	"hsa:3728; P14923; Q15093; Q15151; Q7L3S5; Q86W21; Q9BWC4; Q9HCX9"	"Neutrophil degranulation; RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RHOB GTPase cycle; Formation of the cornified envelope; RHOQ GTPase cycle; RHOJ GTPase cycle; VEGFR2 mediated vascular permeability; Adherens junctions interactions; Regulation of CDH11 function; Regulation of CDH19 Expression and Function; CDH11 homotypic and heterotypic interactions; RHOH GTPase cycle"	"Arrhythmogenic right ventricular cardiomyopathy; Corticotropin-releasing hormone signaling pathway; Ectoderm differentiation; Ectoderm differentiation; Epithelial to mesenchymal transition in colorectal cancer; Opioid receptor pathways"	"21"	"1"	"311.6"	"122.7"	"200.2"	"170.6"	"218.7"	"235.5"	"221.8"	"283.4"	"222.5"	"360.2"	"673.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BXK1"	"Krueppel-like factor 16 OS=Homo sapiens OX=9606 GN=KLF16 PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"252"	"25.4"	"9.88"	"538.26"	"4.69"	"1"	"1"	"signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00096"	"83855"	"ENSG00000129911"	"KLF16"	"hsa:83855; Q9BXK1"	""	""	"0"	"0"	"6.2"	"2.5"	"9.4"	"5.2"	"5.1"	"4.8"	"3.0"	"6.7"	"6.4"	"24.0"	"59.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6ZYL4"	"General transcription factor IIH subunit 5 OS=Homo sapiens OX=9606 GN=GTF2H5 PE=1 SV=1"	"0.000"	""	"21"	"1"	"2"	"1"	"71"	"8.0"	"4.65"	"371.56"	"4.66"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	""	"Pf06331"	"404672"	"ENSG00000272047"	"GTF2H5"	"hsa:404672; Q0P5V8; Q6ZYL4"	"NoRC negatively regulates rRNA expression; TP53 Regulates Transcription of DNA Repair Genes; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Dual Incision in GG-NER; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"32"	"0"	"47.0"	"26.9"	"24.4"	"16.0"	"21.3"	"21.3"	"29.6"	"48.5"	"75.9"	"157.6"	"165.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NI36"	"WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"951"	"105.3"	"7.53"	"395.37"	"4.65"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00400, Pf04192, Pf12894"	"134430"	""	"WDR36"	"A2RUS4; hsa:134430; Q68E02; Q8N1Q2; Q8NI36"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	"50.2"	"21.4"	"43.3"	"53.6"	"46.7"	"48.5"	"38.1"	"51.1"	"48.5"	"166.0"	"351.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N5L8"	"Ribonuclease P protein subunit p25-like protein OS=Homo sapiens OX=9606 GN=RPP25L PE=1 SV=1"	"0.000"	""	"11"	"2"	"4"	"2"	"163"	"17.6"	"10.30"	"581.74"	"4.65"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf01918"	"138716"	"ENSG00000164967"	"RPP25L"	"D3DRM5; hsa:138716; Q8N5L8"	""	""	"0"	"0"	"116.5"	"51.5"	"84.3"	"89.9"	"102.9"	"118.0"	"93.6"	"133.4"	"121.6"	"246.5"	"397.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NQA3"	"WAS protein family homolog 6 OS=Homo sapiens OX=9606 GN=WASH6P PE=1 SV=3"	"0.000"	""	"5"	"2"	"3"	"2"	"447"	"48.0"	"5.67"	"633.95"	"4.65"	"2"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"cytoskeletal activity"	"Pf11945"	""	""	"WASH6P"	"A6NGF1; Q8N305; Q9NQA3"	""	""	"0"	"0"	"94.3"	"38.8"	"86.5"	"68.5"	"90.8"	"111.6"	"75.4"	"110.5"	"74.8"	"114.6"	"234.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60907"	"F-box-like/WD repeat-containing protein TBL1X OS=Homo sapiens OX=9606 GN=TBL1X PE=1 SV=3"	"0.000"	""	"4"	"2"	"3"	"2"	"577"	"62.5"	"6.55"	"971.84"	"4.63"	"2"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400, Pf08513"	"6907"	"ENSG00000101849"	"TBL1X"	"A8K044; A8K4J7; hsa:6907; O60907; Q86UY2"	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; HCMV Early Events; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Heme signaling; BMAL1:CLOCK,NPAS2 activates circadian gene expression; Transcriptional activation of mitochondrial biogenesis; HDACs deacetylate histones; Cytoprotection by HMOX1; Activation of gene expression by SREBF (SREBP); NOTCH1 Intracellular Domain Regulates Transcription; Notch-HLH transcription pathway; Loss of MECP2 binding ability to the NCoR/SMRT complex; Regulation of MECP2 expression and activity; NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux; RORA activates gene expression"	"Ectoderm differentiation; Ectoderm differentiation; Rett syndrome causing genes"	"22"	"0"	"254.7"	"126.0"	"249.1"	"200.4"	"221.4"	"296.7"	"198.0"	"319.9"	"231.2"	"499.3"	"883.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60568"	"Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 OS=Homo sapiens OX=9606 GN=PLOD3 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"738"	"84.7"	"6.05"	"462.48"	"4.61"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"non-structural extracellular;extracellular matrix;other membranes;ER/Golgi"	"other molecular function"	"Pf03171"	"8985"	"ENSG00000106397"	"PLOD3"	"B2R6W6; hsa:8985; O60568; Q540C3"	"Collagen biosynthesis and modifying enzymes"	"VEGFA-VEGFR2 signaling; IL-18 signaling pathway"	"3"	"0"	"34.1"	"17.3"	"31.4"	"32.7"	"37.6"	"38.6"	"35.0"	"36.8"	"34.0"	"77.6"	"129.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8IUF8"	"Ribosomal oxygenase 2 OS=Homo sapiens OX=9606 GN=RIOX2 PE=1 SV=1"	""	""	"6"	"1"	"1"	"1"	"465"	"52.8"	"6.70"	""	"4.61"	""	"1"	"cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf08007, Pf20514"	"84864"	"ENSG00000170854"	"RIOX2"	"D3DN35; hsa:84864; Q6AHW4; Q6SKS0; Q8IU69; Q8IUF6; Q8IUF7; Q8IUF8; Q96C17; Q96KB0"	"HDMs demethylate histones"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96GI7"	"Protein FAM89A OS=Homo sapiens OX=9606 GN=FAM89A PE=1 SV=1"	"0.000"	""	"10"	"1"	"2"	"1"	"184"	"19.6"	"5.92"	"648.99"	"4.58"	"1"	"1"	""	""	""	""	"375061"	"ENSG00000182118"	"FAM89A"	"hsa:375061; Q96GI7"	""	""	"0"	"0"	"19.2"	"5.0"	"16.6"	"8.3"	"11.5"	"15.4"	"15.5"	"29.7"	"44.6"	"83.4"	"175.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O75528"	"Transcriptional adapter 3 OS=Homo sapiens OX=9606 GN=TADA3 PE=1 SV=1"	""	""	"6"	"1"	"1"	"1"	"432"	"48.9"	"6.27"	""	"4.55"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf10198"	"10474"	"ENSG00000171148"	"TADA3"	"hsa:10474; O75528; Q6FI83; Q9UFS2"	"Ub-specific processing proteases; Formation of WDR5-containing histone-modifying complexes; HATs acetylate histones"	""	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15392"	"Baculoviral IAP repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=BIRC5 PE=1 SV=3"	"0.000"	""	"9"	"2"	"3"	"2"	"142"	"16.4"	"5.90"	"787.05"	"4.54"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00653"	"332"	"ENSG00000089685"	"BIRC5"	"A2SUH6; B2R4R1; hsa:332; O15392; Q2I3N8; Q4VGX0; Q53F61; Q5MGC6; Q6FHL2; Q75SP2; Q9P2W8"	"Separation of Sister Chromatids; Neddylation; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; SUMOylation of DNA replication proteins; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Interleukin-4 and Interleukin-13 signaling; TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"	"Apoptosis modulation and signaling; Interleukin-11 signaling pathway; Apoptosis; Apoptosis-related network due to altered Notch3 in ovarian cancer; RAC1/PAK1/p38/MMP2 pathway; Photodynamic therapy-induced HIF-1 survival signaling; Photodynamic therapy-induced NF-kB survival signaling; Hepatitis C and hepatocellular carcinoma; VEGFA-VEGFR2 signaling; IL-4 signaling pathway; Chromosomal and microsatellite instability in colorectal cancer ; Extracellular vesicles in the crosstalk of cardiac cells; Gastrin signaling pathway; Hepatitis B infection"	"24"	"0"	"103.8"	"51.5"	"141.5"	"121.5"	"130.8"	"152.7"	"102.5"	"130.2"	"95.7"	"178.1"	"211.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96ES7"	"SAGA-associated factor 29 OS=Homo sapiens OX=9606 GN=SGF29 PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"293"	"33.2"	"8.10"	""	"4.53"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07039"	"112869"	"ENSG00000176476"	"SGF29"	"hsa:112869; Q96ES7; Q96MF5"	"HATs acetylate histones; Formation of WDR5-containing histone-modifying complexes"	""	"2"	"0"	"7.1"	"4.3"	"9.7"	"4.3"	"8.5"	"9.4"	"7.5"	"7.2"	"12.1"	"48.3"	"79.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14690"	"Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3"	"0.000"	""	"1"	"2"	"4"	"2"	"1871"	"208.6"	"8.87"	"302.50"	"4.53"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00575, Pf05843"	"22984"	"ENSG00000148843"	"PDCD11"	"hsa:22984; Q14690; Q2TA92; Q5W093; Q6P2J3; Q86VQ8; Q9H4P1"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	"233.1"	"79.5"	"203.5"	"154.6"	"178.3"	"195.9"	"157.8"	"164.8"	"132.9"	"170.3"	"85.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14789"	"Golgin subfamily B member 1 OS=Homo sapiens OX=9606 GN=GOLGB1 PE=1 SV=2"	"0.001"	""	"0"	"2"	"3"	"1"	"3259"	"375.8"	"5.00"	"232.74"	"4.53"	"1"	"2"	"cell organization and biogenesis;other biological processes"	"other membranes;cytosol;ER/Golgi"	"nucleic acid binding activity"	""	"2804"	"ENSG00000173230"	"GOLGB1"	"B2ZZ91; D3DN92; E7EP74; F1T0J2; hsa:2804; Q14398; Q14789"	"Golgi Associated Vesicle Biogenesis; COPI-mediated anterograde transport; Signaling by FLT3 fusion proteins"	""	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62877"	"E3 ubiquitin-protein ligase RBX1 OS=Homo sapiens OX=9606 GN=RBX1 PE=1 SV=1"	"0.000"	""	"13"	"1"	"2"	"1"	"108"	"12.3"	"6.96"	"542.21"	"4.52"	"1"	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf12678"	"9978"	"ENSG00000100387"	"RBX1"	"B2RDY1; hsa:9978; P62877; Q8N6Z8; Q9D1S2; Q9WUK9; Q9Y254"	"Potential therapeutics for SARS; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; Dual Incision in GG-NER; Regulation of expression of SLITs and ROBOs; Antigen processing: Ubiquitination & Proteasome degradation; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Degradation of DVL; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; Orc1 removal from chromatin; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Neddylation; Interleukin-1 signaling; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Regulation of BACH1 activity; NOTCH1 Intracellular Domain Regulates Transcription; Formation of TC-NER Pre-Incision Complex; Prolactin receptor signaling; DNA Damage Recognition in GG-NER; Nuclear events stimulated by ALK signaling in cancer; Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling"	"Cell cycle; Dual hijack model of Vif in HIV infection; Type 2 papillary renal cell carcinoma; NRF2-ARE regulation; Hippo-Merlin signaling dysregulation; 22q11.2 copy number variation syndrome; Nucleotide excision repair; Hijack of ubiquitination by SARS-CoV-2; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; 1p36 copy number variation syndrome"	"46"	"0"	"162.0"	"67.6"	"157.2"	"154.7"	"142.7"	"195.7"	"143.7"	"194.1"	"156.1"	"506.8"	"1236.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q15181"	"Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2"	""	""	"7"	"1"	"1"	"1"	"289"	"32.6"	"5.86"	""	"4.51"	""	"1"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00719"	"5464"	"ENSG00000180817"	"PPA1"	"hsa:5464; Q15181; Q2M348; Q5SQT7; Q6P7P4; Q9UQJ5; Q9Y5B1"	"Cytosolic tRNA aminoacylation; Pyrophosphate hydrolysis"	""	"2"	"0"	"27.5"	"11.6"	"19.3"	"15.1"	"27.9"	"33.1"	"43.0"	"88.6"	"54.3"	"55.8"	"135.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75554"	"WW domain-binding protein 4 OS=Homo sapiens OX=9606 GN=WBP4 PE=1 SV=1"	"0.001"	""	"6"	"2"	"3"	"2"	"376"	"42.5"	"5.57"	"289.90"	"4.50"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00397, Pf06220"	"11193"	"ENSG00000120688"	"WBP4"	"B7Z4M2; hsa:11193; O75554; Q32P29"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9C037"	"E3 ubiquitin-protein ligase TRIM4 OS=Homo sapiens OX=9606 GN=TRIM4 PE=1 SV=2"	"0.001"	""	"2"	"1"	"6"	"1"	"500"	"57.4"	"8.10"	"249.01"	"4.50"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00622, Pf00643, Pf15227"	"89122"	"ENSG00000146833"	"TRIM4"	"A4D298; hsa:89122; Q75MK1; Q96F06; Q9C036; Q9C037"	"Antigen processing: Ubiquitination & Proteasome degradation; SARS-CoV-2 activates/modulates innate and adaptive immune responses; TRAF6 mediated NF-kB activation; NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10; Negative regulators of DDX58/IFIH1 signaling; Ovarian tumor domain proteases; TRAF3-dependent IRF activation pathway; TRAF6 mediated IRF7 activation"	""	"9"	"0"	"205.5"	"83.3"	"184.2"	"136.0"	"152.6"	"235.5"	"153.6"	"218.5"	"208.4"	"370.9"	"811.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95433"	"Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1"	"0.000"	""	"5"	"2"	"4"	"2"	"338"	"38.3"	"5.53"	"520.71"	"4.50"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi"	"other molecular function"	"Pf08327, Pf09229"	"10598"	"ENSG00000100591"	"AHSA1"	"B2R9L2; B4DUR9; hsa:10598; O95433; Q96IL6; Q9P060"	""	"T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection"	"1"	"0"	"190.4"	"93.5"	"227.0"	"174.6"	"168.7"	"259.1"	"173.9"	"249.2"	"162.0"	"323.4"	"526.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13889"	"General transcription factor IIH subunit 3 OS=Homo sapiens OX=9606 GN=GTF2H3 PE=1 SV=2"	"0.000"	""	"6"	"1"	"2"	"1"	"308"	"34.4"	"7.02"	"472.71"	"4.49"	"1"	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf03850"	"2967"	"ENSG00000111358"	"GTF2H3"	"B2R819; B4DNZ6; hsa:2967; Q13889; Q7L0G0; Q96AT7"	"NoRC negatively regulates rRNA expression; RNA Polymerase I Promoter Escape; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Dual Incision in GG-NER; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Transcription Termination"	"Eukaryotic transcription initiation; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"33"	"0"	"14.4"	"4.4"	"18.1"	"16.0"	"16.3"	"17.5"	"11.4"	"41.9"	"74.8"	"206.8"	"241.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43663"	"Protein regulator of cytokinesis 1 OS=Homo sapiens OX=9606 GN=PRC1 PE=1 SV=2"	"0.000"	""	"4"	"3"	"5"	"1"	"620"	"71.6"	"6.68"	"1393.99"	"4.49"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03999"	"9055"	"ENSG00000198901"	"PRC1"	"A6NC44; B4DLR1; H9KV59; hsa:9055; O43663; Q9BSB6"	"RHO GTPases activate CIT"	""	"1"	"0"	"31.7"	"15.1"	"30.2"	"31.7"	"28.4"	"34.4"	"22.5"	"36.3"	"28.8"	"164.6"	"364.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IXM2"	"Chromatin complexes subunit BAP18 OS=Homo sapiens OX=9606 GN=BAP18 PE=1 SV=1"	"0.000"	""	"8"	"1"	"2"	"1"	"172"	"17.9"	"7.33"	"418.40"	"4.48"	"1"	"1"	"cell organization and biogenesis"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	""	"124944"	"ENSG00000258315"	"BAP18"	"B4DIV3; C9J4G0; E9PB29; hsa:124944; Q8IXM2"	""	""	"0"	"0"	"57.4"	"21.9"	"47.4"	"31.5"	"44.2"	"52.4"	"43.4"	"56.5"	"44.2"	"95.1"	"149.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49588"	"Alanine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=AARS1 PE=1 SV=2"	"0.001"	""	"1"	"1"	"3"	"1"	"968"	"106.7"	"5.53"	"252.39"	"4.46"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;mitochondrion;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01411, Pf02272, Pf07973"	"16"	"ENSG00000090861"	"AARS1"	"A6NF14; B4DR45; hsa:16; P49588; Q53GV7; Q96FA0"	"Cytosolic tRNA aminoacylation"	"IL-18 signaling pathway"	"2"	"0"	"183.4"	"44.6"	"99.3"	"65.8"	"128.7"	"105.7"	"104.1"	"136.6"	"139.9"	"232.3"	"462.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30405"	"Peptidyl-prolyl cis-trans isomerase F, mitochondrial OS=Homo sapiens OX=9606 GN=PPIF PE=1 SV=1"	"0.001"	""	"8"	"2"	"3"	"2"	"207"	"22.0"	"9.38"	"254.72"	"4.44"	"1"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf00160"	"10105"	"ENSG00000108179"	"PPIF"	"hsa:10105; P30405; Q2YDB7; Q5W131"	""	"Alzheimer's disease and miRNA effects; Alzheimer's disease"	"2"	"0"	"146.1"	"46.6"	"117.7"	"55.5"	"104.0"	"120.7"	"66.5"	"129.6"	"105.7"	"152.9"	"593.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14617"	"AP-3 complex subunit delta-1 OS=Homo sapiens OX=9606 GN=AP3D1 PE=1 SV=1"	"0.000"	""	"2"	"2"	"3"	"2"	"1153"	"130.1"	"8.48"	"314.45"	"4.42"	"1"	"2"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf01602, Pf06375"	"8943"	"ENSG00000065000"	"AP3D1"	"hsa:8943; O00202; O14617; O75262; Q59HF5; Q96G11; Q9H3C6"	""	""	"0"	"0"	"95.9"	"42.5"	"70.4"	"77.7"	"78.7"	"88.5"	"74.0"	"96.4"	"99.7"	"489.0"	"1137.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95785"	"Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1651"	"178.6"	"6.86"	"577.99"	"4.41"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	""	"58525"	"ENSG00000011451"	"WIZ"	"B3KVH1; B7ZM82; hsa:58525; M0QY21; O95785; Q4G0E0; Q6P6B0; Q6ZN24; Q7LDY6; Q7LDZ1; Q96IG5; Q96SQ6; Q9BUR8; Q9NPT1"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99549"	"M-phase phosphoprotein 8 OS=Homo sapiens OX=9606 GN=MPHOSPH8 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"860"	"97.1"	"6.06"	"480.35"	"4.41"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00385, Pf12796"	"54737"	"ENSG00000196199"	"MPHOSPH8"	"B7Z6F9; hsa:54737; Q5JPE5; Q5JTQ0; Q86TK3; Q96MK4; Q99549; Q9BTP1"	""	""	"0"	"0"	"9.5"	"0.0"	"6.3"	"8.8"	"10.0"	"11.8"	"12.0"	"14.0"	"8.4"	"29.0"	"59.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6D9"	"Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2"	"0.001"	""	"5"	"2"	"2"	"2"	"718"	"83.0"	"5.92"	"243.79"	"4.40"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf05557"	"8379"	"ENSG00000002822"	"MAD1L1"	"B3KR41; hsa:8379; Q13312; Q75MI0; Q86UM4; Q9UNH0; Q9Y6D9"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"Cell cycle; Regulation of sister chromatid separation at the metaphase-anaphase transition; Pleural mesothelioma; CCL18 signaling pathway"	"10"	"0"	"19.1"	"11.2"	"23.1"	"16.8"	"19.2"	"18.8"	"19.1"	"25.1"	"19.1"	"44.1"	"76.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86SX6"	"Glutaredoxin-related protein 5, mitochondrial OS=Homo sapiens OX=9606 GN=GLRX5 PE=1 SV=2"	"0.000"	""	"4"	"1"	"4"	"1"	"157"	"16.6"	"6.79"	"509.36"	"4.38"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00462"	"51218"	"ENSG00000182512"	"GLRX5"	"hsa:51218; Q0X088; Q3YML0; Q86SX6; Q86WY3; Q8IZ54"	"Mitochondrial iron-sulfur cluster biogenesis"	"Iron-sulfur cluster biogenesis"	"2"	"0"	"176.7"	"85.4"	"161.4"	"138.5"	"132.8"	"148.4"	"132.1"	"135.0"	"101.4"	"200.0"	"320.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92734"	"Protein TFG OS=Homo sapiens OX=9606 GN=TFG PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"400"	"43.4"	"5.10"	"507.61"	"4.34"	"1"	"1"	"cell organization and biogenesis;transport"	"cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00564"	"10342"	"ENSG00000114354"	"TFG"	"D3DN49; G5E9V1; hsa:10342; K0J5S8; K0J6K2; Q15656; Q92734; Q969I2"	"Signaling by ALK fusions and activated point mutants; COPII-mediated vesicle transport"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2Q9"	"28S ribosomal protein S28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS28 PE=1 SV=1"	"0.000"	""	"10"	"2"	"4"	"2"	"187"	"20.8"	"9.10"	"610.24"	"4.31"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	""	"Pf10246"	"28957"	"ENSG00000147586"	"MRPS28"	"B2RDZ7; hsa:28957; Q96Q21; Q9Y2Q9"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"227.0"	"98.9"	"172.4"	"138.9"	"176.1"	"196.2"	"161.4"	"205.0"	"163.7"	"329.5"	"569.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NEF9"	"Serum response factor-binding protein 1 OS=Homo sapiens OX=9606 GN=SRFBP1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"429"	"48.6"	"9.58"	"387.43"	"4.29"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf09073"	"153443"	"ENSG00000151304"	"SRFBP1"	"hsa:153443; Q5QFI2; Q8NEF9; Q96AH4; Q96DK2"	""	""	"0"	"0"	"25.8"	"13.1"	"21.1"	"25.3"	"16.0"	"31.3"	"23.6"	"43.7"	"30.0"	"48.4"	"65.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6W5"	"Wiskott-Aldrich syndrome protein family member 2 OS=Homo sapiens OX=9606 GN=WASF2 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"498"	"54.3"	"5.53"	"518.62"	"4.28"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02205"	"10163"	"ENSG00000158195"	"WASF2"	"B4DZN0; hsa:10163; O60794; Q9UDY7; Q9Y6W5"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RAC1 GTPase cycle; RHO GTPases Activate WASPs and WAVEs; VEGFA-VEGFR2 Pathway; RAC2 GTPase cycle; RAC3 GTPase cycle"	"Regulation of actin cytoskeleton"	"8"	"0"	"5.8"	"4.1"	"6.1"	"4.2"	"4.4"	"7.7"	"6.3"	"17.9"	"10.0"	"62.7"	"243.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51398"	"28S ribosomal protein S29, mitochondrial OS=Homo sapiens OX=9606 GN=DAP3 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"398"	"45.5"	"8.88"	"433.28"	"4.27"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf10236"	"7818"	"ENSG00000132676"	"DAP3"	"B4DP59; B4DY62; E7EM60; hsa:7818; P51398; Q13044; Q68CT7; Q96Q20"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"CKAP4 signaling pathway map"	"4"	"0"	"37.8"	"14.0"	"28.2"	"21.5"	"32.0"	"29.8"	"30.0"	"40.3"	"47.8"	"91.6"	"140.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULR0"	"Pre-mRNA-splicing factor ISY1 homolog OS=Homo sapiens OX=9606 GN=ISY1 PE=1 SV=3"	"0.000"	""	"7"	"1"	"2"	"1"	"285"	"33.0"	"5.17"	"483.79"	"4.27"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf06246"	"100534599; 57461"	"ENSG00000240682"	"ISY1"	"hsa:100534599; hsa:57461; Q96IL2; Q9BT05; Q9ULR0"	"mRNA Splicing - Major Pathway; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	""	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NR31"	"GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1"	"0.000"	""	"8"	"1"	"2"	"1"	"198"	"22.4"	"6.68"	"610.73"	"4.23"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00025"	"56681"	"ENSG00000079332"	"SAR1A"	"B4DQ19; hsa:56681; Q9NR31"	""	"Sterol regulatory element-binding proteins (SREBP) signaling"	"1"	"0"	"64.9"	"24.7"	"45.5"	"52.7"	"56.0"	"50.6"	"47.8"	"56.3"	"46.0"	"88.5"	"142.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N5F7"	"NF-kappa-B-activating protein OS=Homo sapiens OX=9606 GN=NKAP PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"415"	"47.1"	"10.11"	"385.45"	"4.19"	"1"	"1"	"cell cycle OR cell proliferation;signal transduction;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf06047, Pf15692"	"79576"	"ENSG00000101882"	"NKAP"	"hsa:79576; Q6IPW6; Q8N5F7; Q96BQ2; Q9H638"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"42.3"	"30.3"	"42.2"	"44.8"	"59.9"	"56.1"	"35.9"	"52.5"	"43.5"	"87.0"	"152.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z4G4"	"tRNA (guanine(10)-N2)-methyltransferase homolog OS=Homo sapiens OX=9606 GN=TRMT11 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"463"	"53.4"	"7.78"	"431.44"	"4.15"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01170"	"60487"	"ENSG00000066651"	"TRMT11"	"E1P570; hsa:60487; Q5JY11; Q6PGQ5; Q7Z4G4; Q9HC13"	"tRNA modification in the nucleus and cytosol"	""	"1"	"0"	"16.0"	"9.0"	"13.8"	"14.5"	"15.9"	"23.4"	"14.8"	"20.6"	"19.9"	"36.9"	"88.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P31689"	"DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"397"	"44.8"	"7.08"	"330.76"	"4.13"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00226, Pf00684, Pf01556"	"3301"	"ENSG00000086061"	"DNAJA1"	"hsa:3301; P31689; Q5T7Q0; Q86TL9"	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand"	"VEGFA-VEGFR2 signaling; Exercise-induced circadian regulation"	"3"	"0"	"174.3"	"62.4"	"143.5"	"119.7"	"154.7"	"163.6"	"137.0"	"197.8"	"158.2"	"323.0"	"580.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQP7"	"Mitochondrial genome maintenance exonuclease 1 OS=Homo sapiens OX=9606 GN=MGME1 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"344"	"39.4"	"7.68"	"480.63"	"4.13"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response"	"mitochondrion"	"other molecular function"	"Pf12705"	"92667"	"ENSG00000125871"	"MGME1"	"B2RDG5; D3DW29; hsa:92667; Q96SW3; Q9BQP7"	""	"Primary ovarian insufficiency"	"1"	"0"	"16.3"	"7.0"	"16.4"	"12.3"	"16.1"	"17.8"	"14.9"	"22.8"	"12.9"	"27.9"	"70.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5QJE6"	"Deoxynucleotidyltransferase terminal-interacting protein 2 OS=Homo sapiens OX=9606 GN=DNTTIP2 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"756"	"84.4"	"6.16"	"482.40"	"4.11"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf08698"	"30836"	"ENSG00000067334"	"DNTTIP2"	"hsa:30836; Q12987; Q53H59; Q5QJE6; Q5TFJ4; Q6TLI0; Q76MJ8; Q86WX9"	""	""	"0"	"0"	"80.9"	"45.3"	"73.7"	"83.5"	"90.8"	"98.8"	"89.2"	"112.2"	"89.2"	"125.4"	"203.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P60604"	"Ubiquitin-conjugating enzyme E2 G2 OS=Homo sapiens OX=9606 GN=UBE2G2 PE=1 SV=1"	""	""	"15"	"1"	"1"	"1"	"165"	"18.6"	"4.70"	""	"4.08"	""	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf00179"	"7327"	"ENSG00000184787"	"UBE2G2"	"A6NMQ7; A8K3L4; D3DSL7; hsa:7327; P56554; P60604"	"Antigen processing: Ubiquitination & Proteasome degradation; Synthesis of active ubiquitin: roles of E1 and E2 enzymes"	"Parkin-ubiquitin proteasomal system pathway; Parkinson's disease pathway"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43768"	"Alpha-endosulfine OS=Homo sapiens OX=9606 GN=ENSA PE=1 SV=1"	"0.000"	""	"12"	"1"	"2"	"1"	"121"	"13.4"	"7.24"	"478.61"	"4.07"	"1"	"1"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf04667"	"2029"	"ENSG00000143420"	"ENSA"	"A8K1Z9; E9PB69; hsa:2029; O43768; Q5T5H2; Q68D48; Q6FHW0; Q6IAM4; Q6NUL2; Q6VUC6; Q6VUC7; Q6VUC8; Q6VUC9; Q6VUD0; Q6VUD1; Q9NRZ0"	"MASTL Facilitates Mitotic Progression"	""	"1"	"0"	"45.0"	"19.3"	"40.3"	"32.4"	"46.9"	"44.3"	"32.0"	"40.5"	"27.9"	"51.7"	"85.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H6R4"	"Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1146"	"127.5"	"7.64"	"596.17"	"4.05"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"mitochondrion;nucleus;other cell component"	""	"Pf03813, Pf17403, Pf17404, Pf17405, Pf17406, Pf17407"	"65083"	"ENSG00000165271"	"NOL6"	"hsa:65083; Q5T5M3; Q5T5M4; Q7L4G6; Q8N6I0; Q8TEY9; Q8TEZ0; Q8TEZ1; Q9H675; Q9H6R4"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	"13.2"	"2.7"	"10.5"	"8.3"	"12.3"	"13.8"	"7.7"	"11.3"	"12.4"	"50.3"	"112.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01970"	"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 OS=Homo sapiens OX=9606 GN=PLCB3 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1234"	"138.7"	"5.90"	"451.52"	"4.04"	"1"	"1"	"other metabolic processes;transport;signal transduction;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00168, Pf00387, Pf00388, Pf08703, Pf09279, Pf17787"	"5331"	"ENSG00000149782"	"PLCB3"	"A5PKZ6; G5E960; hsa:5331; Q01970; Q8N1A4"	"G alpha (q) signalling events; Ca2+ pathway; G beta:gamma signalling through PLC beta; Presynaptic function of Kainate receptors; Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion; Synthesis of IP3 and IP4 in the cytosol; PLC beta mediated events; Acetylcholine regulates insulin secretion"	"Alzheimer's disease and miRNA effects; S1P receptor signal transduction; Myometrial relaxation and contraction pathways; G protein signaling pathways; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; GPR40 pathway; MAPK cascade; Wnt signaling; Non-genomic actions of 1,25 dihydroxyvitamin D3; Resistin as a regulator of inflammation; Hippo signaling regulation pathways; PKC-gamma calcium signaling pathway in ataxia; Kisspeptin/kisspeptin receptor system in the ovary; GPR143 in melanocytes and retinal pigment epithelium cells; Neuroinflammation and glutamatergic signaling; Alzheimer's disease; Calcium regulation in cardiac cells"	"26"	"0"	"13.4"	"7.4"	"16.8"	"14.8"	"15.3"	"13.4"	"11.7"	"19.9"	"16.7"	"44.6"	"90.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96BN2"	"Transcriptional adapter 1 OS=Homo sapiens OX=9606 GN=TADA1 PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"335"	"37.4"	"7.39"	""	"4.02"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf12767"	"117143"	"ENSG00000152382"	"TADA1"	"A8K4J9; hsa:117143; Q96BN2"	"HATs acetylate histones"	""	"1"	"0"	"37.0"	"10.7"	"28.0"	"25.9"	"37.7"	"26.8"	"25.0"	"40.6"	"25.4"	"91.8"	"188.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92793"	"CREB-binding protein OS=Homo sapiens OX=9606 GN=CREBBP PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"2442"	"265.2"	"8.53"	"418.50"	"4.01"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00439, Pf00569, Pf02135, Pf02172, Pf06001, Pf08214, Pf09030"	"1387"	"ENSG00000005339"	"CREBBP"	"D3DUC9; hsa:1387; O00147; Q16376; Q4LE28; Q92793"	"SUMOylation of transcription cofactors; Formation of paraxial mesoderm; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Pre-NOTCH Transcription and Translation; NOTCH1 Intracellular Domain Regulates Transcription; Notch-HLH transcription pathway; NOTCH3 Intracellular Domain Regulates Transcription; Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells; NOTCH4 Intracellular Domain Regulates Transcription; RUNX3 regulates NOTCH signaling; SARS-CoV-2 activates/modulates innate and adaptive immune responses; PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; NPAS4 regulates expression of target genes; Heme signaling; Formation of the beta-catenin:TCF transactivating complex; BMAL1:CLOCK,NPAS2 activates circadian gene expression; Transcriptional activation of mitochondrial biogenesis; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Cytoprotection by HMOX1; Activation of gene expression by SREBF (SREBP); NFE2L2 regulating anti-oxidant/detoxification enzymes; HATs acetylate histones; TP53 Regulates Transcription of Genes Involved in Cytochrome C Release; Nuclear events mediated by NFE2L2; NFE2L2 regulates pentose phosphate pathway genes; FOXO-mediated transcription of cell death genes; Regulation of FOXO transcriptional activity by acetylation; RORA activates gene expression; Attenuation phase; CD209 (DC-SIGN) signaling; Activation of the TFAP2 (AP-2) family of transcription factors; TRAF3-dependent IRF activation pathway; TRAF6 mediated IRF7 activation; Regulation of gene expression by Hypoxia-inducible Factor; RUNX1 regulates transcription of genes involved in differentiation of myeloid cells; LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production"	"Androgen receptor signaling pathway; Angiogenesis; TNF-alpha signaling pathway; Notch signaling; Initiation of transcription and translation elongation at the HIV-1 LTR; IL6 signaling pathway; Pathways affected in adenoid cystic carcinoma; Hematopoietic stem cell gene regulation by GABP alpha/beta complex; VEGFA-VEGFR2 signaling; Wnt signaling pathway and pluripotency; Clear cell renal cell carcinoma pathways; Ebola virus infection in host; Type 2 papillary renal cell carcinoma; Ciliary landscape; Hepatitis B infection; Male infertility; TGF-beta receptor signaling in skeletal dysplasias; Overlap between signal transduction pathways contributing to LMNA laminopathies; 15q13.3 copy number variation syndrome; Urotensin-II-mediated signaling pathway; 15q11q13 copy number variation; TGF-beta receptor signaling; Sudden infant death syndrome (SIDS) susceptibility pathways"	"64"	"0"	"24.9"	"12.1"	"25.3"	"17.2"	"19.2"	"33.0"	"19.1"	"34.5"	"29.1"	"55.1"	"119.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q68DK7"	"Male-specific lethal 1 homolog OS=Homo sapiens OX=9606 GN=MSL1 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"614"	"67.1"	"8.92"	"315.40"	"4.01"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf15275, Pf16801"	"339287"	"ENSG00000188895"	"MSL1"	"hsa:339287; Q0VF46; Q68DK7; Q69Z03"	"HATs acetylate histones"	""	"1"	"0"	"17.9"	"7.0"	"14.5"	"16.6"	"14.9"	"18.4"	"14.0"	"20.9"	"12.0"	"39.3"	"87.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EY1"	"DnaJ homolog subfamily A member 3, mitochondrial OS=Homo sapiens OX=9606 GN=DNAJA3 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"480"	"52.5"	"9.26"	"484.52"	"4.01"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00226, Pf00684, Pf01556"	"9093"	"ENSG00000103423; ENSG00000276726"	"DNAJA3"	"B2RAJ5; B4DI33; E7ES32; hsa:9093; O75472; Q8WUJ6; Q8WXJ3; Q96D76; Q96EY1; Q96IV1; Q9NYH8"	""	""	"0"	"0"	"46.2"	"16.8"	"45.0"	"34.0"	"40.5"	"53.6"	"34.0"	"50.3"	"43.6"	"92.5"	"185.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q13685"	"Angio-associated migratory cell protein OS=Homo sapiens OX=9606 GN=AAMP PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"434"	"46.7"	"4.42"	""	"3.99"	""	"1"	"developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00400"	"14"	"ENSG00000127837"	"AAMP"	"hsa:14; Q13685; Q8WUJ9; Q96H92"	"Thromboxane signalling through TP receptor; Signaling by EGFR; NOD1/2 Signaling Pathway; Signaling by VEGF"	"Nucleotide-binding oligomerization domain (NOD) pathway"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UPY6"	"Wiskott-Aldrich syndrome protein family member 3 OS=Homo sapiens OX=9606 GN=WASF3 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"502"	"55.3"	"6.43"	"521.56"	"3.99"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02205"	"10810"	"ENSG00000132970"	"WASF3"	"hsa:10810; O94974; Q86VQ2; Q9UPY6"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; VEGFA-VEGFR2 Pathway; RAC1 GTPase cycle"	""	"5"	"0"	"8.9"	"4.2"	"5.2"	"8.7"	"11.8"	"11.1"	"8.7"	"12.0"	"12.5"	"28.1"	"38.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75347"	"Tubulin-specific chaperone A OS=Homo sapiens OX=9606 GN=TBCA PE=1 SV=3"	"0.000"	""	"10"	"1"	"2"	"1"	"108"	"12.8"	"5.29"	"508.27"	"3.98"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02970"	"6902"	"ENSG00000171530"	"TBCA"	"B4DT30; hsa:6902; O75347"	"Post-chaperonin tubulin folding pathway"	"VEGFA-VEGFR2 signaling"	"2"	"0"	"26.3"	"11.6"	"22.7"	"13.9"	"22.4"	"22.5"	"22.9"	"28.1"	"28.6"	"48.3"	"112.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NYB9"	"Abl interactor 2 OS=Homo sapiens OX=9606 GN=ABI2 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"513"	"55.6"	"6.16"	"438.85"	"3.97"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07815, Pf14604"	"10152"	"ENSG00000138443"	"ABI2"	"B4DSN1; hsa:10152; Q13147; Q13249; Q13801; Q9BV70; Q9NYB9"	"RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; VEGFA-VEGFR2 Pathway"	"Regulation of actin cytoskeleton"	"8"	"0"	"59.1"	"34.0"	"49.2"	"46.0"	"45.2"	"65.0"	"53.2"	"76.2"	"78.9"	"215.2"	"377.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6SPF0"	"Atherin OS=Homo sapiens OX=9606 GN=SAMD1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"538"	"56.0"	"7.58"	"407.52"	"3.96"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"other molecular function"	"Pf00536"	"90378"	"ENSG00000288488"	"SAMD1"	"hsa:90378; Q6P0R3; Q6PIS7; Q6SPF0; Q96IM4"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P56385"	"ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2"	"0.000"	""	"20"	"1"	"2"	"1"	"69"	"7.9"	"9.35"	"421.42"	"3.96"	"1"	"1"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf05680"	"521"	"ENSG00000169020"	"ATP5ME"	"hsa:521; P56385; Q0D2L9"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"Electron transport chain: OXPHOS system in mitochondria; Oxidative phosphorylation"	"4"	"0"	"77.3"	"34.5"	"63.2"	"48.9"	"62.9"	"77.1"	"63.8"	"72.8"	"65.6"	"104.9"	"158.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96SK2"	"Transmembrane protein 209 OS=Homo sapiens OX=9606 GN=TMEM209 PE=1 SV=2"	""	""	"4"	"1"	"1"	"1"	"561"	"62.9"	"8.63"	""	"3.95"	""	"1"	""	"other membranes"	""	"Pf09786"	"84928"	"ENSG00000146842"	"TMEM209"	"A4D1L1; hsa:84928; Q49A50; Q6PF00; Q8NCH3; Q96SK2; Q96SL6"	""	""	"0"	"0"	"14.2"	"12.1"	"10.4"	"9.6"	"15.8"	"9.7"	"9.1"	"11.7"	"16.4"	"30.4"	"46.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75586"	"Mediator of RNA polymerase II transcription subunit 6 OS=Homo sapiens OX=9606 GN=MED6 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"246"	"28.4"	"8.62"	"450.65"	"3.95"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf04934"	"10001"	"ENSG00000133997"	"MED6"	"B4DU17; B4E2P0; hsa:10001; O15401; O75586; Q53FE3; Q53HJ3; Q6FHQ4; Q9BTH1; Q9UHL1"	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; Generic Transcription Pathway"	""	"3"	"0"	"8.1"	"4.4"	"8.7"	"9.2"	"9.5"	"10.3"	"13.8"	"13.5"	"12.8"	"30.0"	"42.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q00403"	"Transcription initiation factor IIB OS=Homo sapiens OX=9606 GN=GTF2B PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"316"	"34.8"	"8.35"	"440.32"	"3.95"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00382, Pf08271"	"2959"	"ENSG00000137947"	"GTF2B"	"A8K1A7; hsa:2959; Q00403; Q5JS30"	"RNA Polymerase II Pre-transcription Events; RNA polymerase II transcribes snRNA genes; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation"	"Eukaryotic transcription initiation"	"10"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14406"	"Cytochrome c oxidase subunit 7A2, mitochondrial OS=Homo sapiens OX=9606 GN=COX7A2 PE=1 SV=1"	"0.000"	""	"16"	"1"	"2"	"1"	"83"	"9.4"	"9.76"	"362.46"	"3.94"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf02238"	"1347"	"ENSG00000112695"	"COX7A2"	"B2R5E1; hsa:1347; P14406; Q3MIH5; Q5TF59; Q6FGI2"	""	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly"	"3"	"0"	"123.6"	"37.9"	"65.1"	"54.9"	"80.3"	"75.3"	"63.4"	"87.9"	"68.8"	"137.8"	"258.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15436"	"Protein transport protein Sec23A OS=Homo sapiens OX=9606 GN=SEC23A PE=1 SV=2"	"0.000"	""	"2"	"1"	"3"	"1"	"765"	"86.1"	"7.08"	"937.24"	"3.91"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00626, Pf04810, Pf04811, Pf04815, Pf08033"	"10484"	"ENSG00000100934"	"SEC23A"	"B2R5P4; B3KXI2; hsa:10484; Q15436; Q8NE16"	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC; COPII-mediated vesicle transport; MHC class II antigen presentation; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Cargo concentration in the ER; Regulation of cholesterol biosynthesis by SREBP (SREBF)"	"Sterol regulatory element-binding proteins (SREBP) signaling"	"7"	"0"	"57.2"	"30.2"	"51.6"	"51.6"	"53.3"	"71.1"	"48.7"	"54.9"	"44.2"	"94.8"	"113.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P47914"	"60S ribosomal protein L29 OS=Homo sapiens OX=9606 GN=RPL29 PE=1 SV=2"	"0.000"	""	"9"	"1"	"2"	"1"	"159"	"17.7"	"11.66"	"425.18"	"3.91"	"1"	"1"	"protein metabolism;other metabolic processes;developmental processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01779"	"6159"	"ENSG00000162244"	"RPL29"	"A8K0H3; B2R4M8; hsa:6159; P47914; Q6IPY3"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"201.0"	"93.2"	"190.4"	"163.2"	"175.2"	"192.2"	"138.3"	"199.9"	"146.8"	"224.7"	"284.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12800"	"Alpha-globin transcription factor CP2 OS=Homo sapiens OX=9606 GN=TFCP2 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"502"	"57.2"	"5.80"	"396.00"	"3.87"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04516, Pf18016"	"7024"	"ENSG00000135457"	"TFCP2"	"A8K5E9; hsa:7024; Q12800; Q12801; Q9UD75; Q9UD77"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"15.9"	"9.2"	"20.3"	"21.2"	"13.3"	"18.1"	"16.1"	"21.8"	"28.6"	"75.7"	"145.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q53EL6"	"Programmed cell death protein 4 OS=Homo sapiens OX=9606 GN=PDCD4 PE=1 SV=2"	"0.000"	""	"6"	"3"	"4"	"3"	"469"	"51.7"	"5.21"	"913.29"	"3.87"	"3"	"1"	"developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf02847"	"27250"	"ENSG00000150593"	"PDCD4"	"B2RCV4; B5ME91; hsa:27250; O15501; Q53EL6; Q5VZS6; Q6PJI5; Q8TAR5; Q99834"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"Translation inhibitors in chronically activated PDGFRA cells; A network map of Macrophage-stimulating protein (MSP) signaling; Interferon type I signaling pathways"	"4"	"0"	"235.5"	"97.1"	"203.5"	"169.4"	"203.9"	"221.2"	"169.7"	"233.4"	"196.3"	"296.6"	"440.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N0Z6"	"Tetratricopeptide repeat protein 5 OS=Homo sapiens OX=9606 GN=TTC5 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"440"	"48.9"	"6.48"	"328.57"	"3.86"	"1"	"1"	"DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf16669"	"91875"	"ENSG00000136319"	"TTC5"	"A8MQ18; hsa:91875; Q8N0Z6; Q96HF9"	"Regulation of TP53 Activity through Methylation"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53985"	"Monocarboxylate transporter 1 OS=Homo sapiens OX=9606 GN=SLC16A1 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"500"	"53.9"	"8.66"	"407.56"	"3.86"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"transporter activity;other molecular function"	"Pf07690"	"6566"	"ENSG00000155380; ENSG00000281917"	"SLC16A1"	"hsa:6566; P53985; Q49A45; Q5T8R6; Q9NSJ9"	"Pyruvate metabolism; Aspirin ADME; Basigin interactions; Proton-coupled monocarboxylate transport; Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT)"	"Photodynamic therapy-induced HIF-1 survival signaling; Fragile X syndrome; Glucose metabolism in triple-negative breast cancer cells"	"8"	"0"	"57.0"	"23.5"	"50.3"	"46.3"	"45.7"	"48.0"	"41.9"	"56.5"	"69.4"	"82.5"	"113.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P43155"	"Carnitine O-acetyltransferase OS=Homo sapiens OX=9606 GN=CRAT PE=1 SV=5"	"0.000"	""	"3"	"2"	"3"	"2"	"626"	"70.8"	"8.44"	"666.26"	"3.82"	"2"	"1"	"other metabolic processes"	"other membranes;cytosol;mitochondrion;ER/Golgi;other cytoplasmic organelle"	"other molecular function"	"Pf00755"	"1384"	"ENSG00000095321"	"CRAT"	"P43155; Q5T952; Q9BW16"	"Peroxisomal protein import; Beta-oxidation of pristanoyl-CoA"	"Fatty acid beta-oxidation"	"3"	"0"	"138.9"	"77.0"	"126.6"	"127.2"	"131.0"	"170.4"	"123.2"	"168.8"	"143.4"	"610.0"	"915.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IVM0"	"Coiled-coil domain-containing protein 50 OS=Homo sapiens OX=9606 GN=CCDC50 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"306"	"35.8"	"6.65"	"472.87"	"3.81"	"1"	"1"	"other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf15295"	"152137"	"ENSG00000152492"	"CCDC50"	"hsa:152137; Q86VH7; Q8IVM0"	""	""	"0"	"0"	"56.6"	"38.9"	"43.4"	"40.6"	"50.1"	"57.4"	"43.6"	"59.6"	"61.2"	"93.2"	"205.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P04080"	"Cystatin-B OS=Homo sapiens OX=9606 GN=CSTB PE=1 SV=2"	"0.000"	""	"12"	"1"	"2"	"1"	"98"	"11.1"	"7.56"	"383.09"	"3.78"	"1"	"1"	"other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00031"	"1476"	"ENSG00000160213"	"CSTB"	"hsa:1476; P04080"	"Neutrophil degranulation"	""	"1"	"0"	"38.5"	"18.9"	"32.9"	"37.8"	"38.2"	"44.0"	"29.8"	"49.2"	"62.8"	"220.1"	"530.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NUW8"	"Tyrosyl-DNA phosphodiesterase 1 OS=Homo sapiens OX=9606 GN=TDP1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"608"	"68.4"	"7.65"	"409.62"	"3.78"	"1"	"1"	"DNA metabolism;other metabolic processes;stress response"	"plasma membrane;other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06087"	"55775"	"ENSG00000042088"	"TDP1"	"hsa:55775; Q2HXX4; Q86TV8; Q96BK7; Q9NUW8; Q9NZM7; Q9NZM8"	"Nonhomologous End-Joining (NHEJ)"	""	"1"	"0"	"31.3"	"14.3"	"27.8"	"33.4"	"26.7"	"41.0"	"52.1"	"78.8"	"55.3"	"79.8"	"95.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62891"	"60S ribosomal protein L39 OS=Homo sapiens OX=9606 GN=RPL39 PE=1 SV=2"	"0.000"	""	"20"	"1"	"2"	"1"	"51"	"6.4"	"12.56"	"332.39"	"3.78"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"non-structural extracellular;cytosol;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00832"	"6170"	"ENSG00000198918"	"RPL39"	"hsa:6170; P02404; P39025; P62891; Q9BYF2"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"62.8"	"21.8"	"58.1"	"47.2"	"57.6"	"55.4"	"35.7"	"57.0"	"44.4"	"87.7"	"126.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61244"	"Protein max OS=Homo sapiens OX=9606 GN=MAX PE=1 SV=1"	"0.000"	""	"11"	"2"	"3"	"2"	"160"	"18.3"	"6.30"	"709.61"	"3.78"	"2"	"1"	"cell organization and biogenesis;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00010"	"4149"	"ENSG00000125952"	"MAX"	"A6NH73; A8K265; A8K4G4; A8K824; hsa:4149; P25912; P52163; P61244; Q14803; Q96CY8"	"Transcriptional Regulation by E2F6; Cyclin E associated events during G1/S transition ; Transcription of E2F targets under negative control by DREAM complex; Cyclin A:Cdk2-associated events at S phase entry"	"B cell receptor signaling pathway; Pathways affected in adenoid cystic carcinoma; MAPK signaling pathway; p38 MAPK signaling pathway; Small cell lung cancer; Pleural mesothelioma; 5q35 copy number variation"	"11"	"0"	"246.3"	"121.7"	"216.9"	"202.7"	"226.8"	"262.8"	"267.6"	"384.1"	"275.7"	"368.0"	"542.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P28072"	"Proteasome subunit beta type-6 OS=Homo sapiens OX=9606 GN=PSMB6 PE=1 SV=4"	"0.000"	""	"5"	"1"	"2"	"1"	"239"	"25.3"	"4.92"	"404.49"	"3.77"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00227"	"5694"	"ENSG00000142507"	"PSMB6"	"hsa:5694; P28072; Q96J55"	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A; MAPK6/MAPK4 signaling; The role of GTSE1 in G2/M progression after G2 checkpoint; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"62"	"0"	"238.5"	"102.7"	"201.5"	"209.4"	"224.7"	"214.1"	"200.2"	"278.7"	"232.8"	"346.2"	"354.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52756"	"RNA-binding protein 5 OS=Homo sapiens OX=9606 GN=RBM5 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"815"	"92.1"	"6.28"	"477.55"	"3.75"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00641, Pf01585, Pf17780"	"10181"	"ENSG00000003756"	"RBM5"	"B2RA45; B4DM16; B4DMF9; B4DZ63; hsa:10181; P52756; Q93021; Q9BU14; Q9HDA6; Q9UKY8; Q9UL24"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"0"	"78.9"	"22.1"	"54.2"	"49.6"	"55.4"	"57.1"	"44.2"	"56.3"	"49.7"	"98.1"	"151.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P43686"	"26S proteasome regulatory subunit 6B OS=Homo sapiens OX=9606 GN=PSMC4 PE=1 SV=2"	"0.001"	""	"5"	"1"	"2"	"1"	"418"	"47.3"	"5.21"	"245.64"	"3.73"	"1"	"1"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf16450, Pf17862"	"5704"	"ENSG00000013275; ENSG00000281221"	"PSMC4"	"hsa:5704; P43686; Q96FV5; Q9UBM3; Q9UEX3"	"Regulation of RAS by GAPs; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; UCH proteinases; Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"64"	"0"	"13.7"	"7.7"	"10.4"	"12.9"	"12.7"	"16.3"	"17.7"	"18.0"	"9.9"	"18.9"	"28.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8N0X4"	"Citramalyl-CoA lyase, mitochondrial OS=Homo sapiens OX=9606 GN=CLYBL PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"340"	"37.3"	"8.73"	""	"3.73"	""	"1"	"cell organization and biogenesis;other biological processes"	"mitochondrion"	"other molecular function"	"Pf03328"	"171425"	"ENSG00000125246"	"CLYBL"	"hsa:171425; Q5W0F7; Q8N0X4; Q8TDH8"	""	""	"0"	"0"	"9.5"	"4.5"	"9.4"	"10.8"	"10.4"	"8.2"	"9.3"	"13.7"	"13.9"	"159.7"	"325.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BXI6"	"TBC1 domain family member 10A OS=Homo sapiens OX=9606 GN=TBC1D10A PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"508"	"57.1"	"8.44"	"436.51"	"3.72"	"1"	"1"	"protein metabolism;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00566"	"83874"	"ENSG00000099992"	"TBC1D10A"	"B3KXT8; hsa:83874; O76053; Q20WK7; Q543A2; Q9BXI6"	"TBC/RABGAPs"	"Deregulation of Rab and Rab effector genes in bladder cancer"	"2"	"0"	"30.3"	"16.2"	"28.3"	"26.0"	"24.5"	"37.0"	"31.0"	"62.8"	"80.7"	"325.2"	"479.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H2P0"	"Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1102"	"123.5"	"7.34"	"370.39"	"3.72"	"1"	"1"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00046, Pf19627"	"23394"	"ENSG00000101126"	"ADNP"	"E1P5Y2; hsa:23394; O94881; Q5BKU2; Q9H2P0; Q9UG34"	""	""	"0"	"0"	"31.9"	"14.7"	"25.3"	"25.0"	"24.8"	"22.1"	"28.5"	"36.1"	"28.3"	"55.6"	"93.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60911"	"Cathepsin L2 OS=Homo sapiens OX=9606 GN=CTSV PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"334"	"37.3"	"8.76"	"489.62"	"3.71"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;other cytoplasmic organelle"	"enzyme regulator activity;other molecular function"	"Pf00112, Pf08246"	"1515"	"ENSG00000136943"	"CTSV"	"hsa:1515; O60233; O60911; Q2TB86; Q5T1U0"	"MHC class II antigen presentation; Assembly of collagen fibrils and other multimeric structures; RUNX1 regulates transcription of genes involved in differentiation of keratinocytes; Trafficking and processing of endosomal TLR; Endosomal/Vacuolar pathway; Activation of Matrix Metalloproteinases"	"Endochondral ossification; Endochondral ossification with skeletal dysplasias; Pancreatic cancer subtypes"	"10"	"0"	"33.3"	"13.4"	"26.7"	"19.4"	"27.4"	"37.0"	"22.0"	"40.2"	"34.3"	"127.7"	"189.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00273"	"DNA fragmentation factor subunit alpha OS=Homo sapiens OX=9606 GN=DFFA PE=1 SV=1"	"0.000"	""	"7"	"2"	"3"	"2"	"331"	"36.5"	"4.79"	"787.64"	"3.71"	"2"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02017, Pf09033"	"1676"	"ENSG00000160049"	"DFFA"	"hsa:1676; O00273; Q5T6G5; Q5T6G6; Q96I97; Q9Y6C6"	"Apoptosis induced DNA fragmentation"	"Apoptosis; Fas ligand pathway and stress induction of heat shock proteins; Acute viral myocarditis"	"4"	"0"	"86.0"	"39.0"	"86.7"	"59.8"	"68.7"	"70.2"	"59.7"	"89.2"	"70.2"	"153.1"	"231.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P47756"	"F-actin-capping protein subunit beta OS=Homo sapiens OX=9606 GN=CAPZB PE=1 SV=4"	"0.000"	""	"4"	"1"	"2"	"1"	"277"	"31.3"	"5.59"	"485.23"	"3.70"	"1"	"1"	"cell organization and biogenesis"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf01115"	"100612860; 101140941"	"ENSGGOG00000003982; ENSPPYG00000001789; ENSPTRG00000000268"	"CAPZB"	"A0A2J8KEQ9; A0A2J8T2J3; A0A6D2W7V0; A0A6D2XKL1; A0A8B6ZIG4; A0A9B0TL78; G3QN07; H2N8T0; H2R9E0"	""	""	"0"	"0"	"110.3"	"44.9"	"103.7"	"94.0"	"88.8"	"127.2"	"85.4"	"106.3"	"76.2"	"202.9"	"316.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HD34"	"LYR motif-containing protein 4 OS=Homo sapiens OX=9606 GN=LYRM4 PE=1 SV=1"	"0.000"	""	"12"	"1"	"2"	"1"	"91"	"10.8"	"10.73"	"345.36"	"3.70"	"1"	"1"	"cell organization and biogenesis;other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf05347"	"57128"	"ENSG00000214113"	"LYRM4"	"A8K543; hsa:57128; Q5XKP1; Q9HD34"	"Mitochondrial iron-sulfur cluster biogenesis"	"Iron-sulfur cluster biogenesis"	"2"	"0"	"69.1"	"25.0"	"58.8"	"64.1"	"52.3"	"72.1"	"46.9"	"82.1"	"94.4"	"328.1"	"619.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96MF7"	"E3 SUMO-protein ligase NSE2 OS=Homo sapiens OX=9606 GN=NSMCE2 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"247"	"27.9"	"7.74"	"327.64"	"3.69"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf11789"	"286053"	"ENSG00000156831"	"NSMCE2"	"hsa:286053; Q8N549; Q96MF7"	"SUMOylation of DNA damage response and repair proteins"	""	"1"	"0"	"93.9"	"49.2"	"76.0"	"55.8"	"69.9"	"75.1"	"64.6"	"91.8"	"80.4"	"197.3"	"509.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BTT6"	"Leucine-rich repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=LRRC1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"524"	"59.2"	"5.02"	"364.40"	"3.68"	"1"	"1"	""	"other membranes;cytosol"	""	"Pf13855"	"55227"	"ENSG00000137269"	"LRRC1"	"hsa:55227; Q5TGN3; Q9BTT6; Q9HAC0; Q9NVF1"	"RND2 GTPase cycle"	""	"1"	"0"	"15.3"	"5.8"	"9.3"	"6.5"	"8.3"	"11.9"	"7.6"	"11.4"	"14.2"	"19.9"	"37.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62875"	"DNA-directed RNA polymerases I, II, and III subunit RPABC5 OS=Homo sapiens OX=9606 GN=POLR2L PE=1 SV=1"	"0.000"	""	"16"	"1"	"2"	"1"	"67"	"7.6"	"7.77"	"410.31"	"3.67"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01194"	"5441"	"ENSG00000177700"	"POLR2L"	"hsa:5441; P52436; P62875; Q6FHX3"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; B-WICH complex positively regulates rRNA expression; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; mRNA Splicing - Major Pathway; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"Pyrimidine metabolism; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"56"	"0"	"37.1"	"15.0"	"38.7"	"33.1"	"37.2"	"50.0"	"44.5"	"59.6"	"101.2"	"223.1"	"411.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N6H7"	"ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1"	"0.000"	""	"3"	"2"	"3"	"2"	"521"	"56.7"	"7.99"	"680.71"	"3.66"	"2"	"1"	"cell organization and biogenesis;transport"	"plasma membrane;other membranes;cytosol;ER/Golgi"	"enzyme regulator activity;other molecular function"	"Pf01412"	"84364"	"ENSG00000149182"	"ARFGAP2"	"B4DX29; B7Z9M7; D3DQQ9; hsa:84364; Q3LIF2; Q8N3I1; Q8N6H7; Q96SX7"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport; CDC42 GTPase cycle"	"IL-18 signaling pathway; 5q35 copy number variation"	"5"	"0"	"159.7"	"82.2"	"176.7"	"164.7"	"161.7"	"192.1"	"138.3"	"183.0"	"127.2"	"306.9"	"559.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4K4"	"Mitogen-activated protein kinase kinase kinase kinase 5 OS=Homo sapiens OX=9606 GN=MAP4K5 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"846"	"95.0"	"7.83"	"540.16"	"3.65"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction"	"plasma membrane;other membranes;cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00780"	"11183"	"ENSG00000012983"	"MAP4K5"	"A0A0A0MQR1; hsa:11183; Q8IYF6; Q9Y4K4"	""	"Angiopoietin-like protein 8 regulatory pathway; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Insulin signaling"	"3"	"0"	"64.8"	"35.3"	"68.5"	"60.2"	"77.3"	"74.0"	"60.6"	"127.2"	"140.9"	"499.8"	"842.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H2W6"	"39S ribosomal protein L46, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL46 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"279"	"31.7"	"7.05"	"297.32"	"3.65"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf11788"	"26589"	"ENSG00000259494"	"MRPL46"	"B2RD75; hsa:26589; Q9H2W6; Q9HBU8"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"67.3"	"28.1"	"51.1"	"40.2"	"56.4"	"60.5"	"53.7"	"68.6"	"55.9"	"99.0"	"200.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BV81"	"ER membrane protein complex subunit 6 OS=Homo sapiens OX=9606 GN=EMC6 PE=1 SV=1"	"0.000"	""	"12"	"1"	"2"	"1"	"110"	"12.0"	"10.07"	"456.00"	"3.63"	"1"	"1"	"cell organization and biogenesis;other metabolic processes"	"other membranes;ER/Golgi"	""	"Pf07019"	"83460"	"ENSG00000127774"	"EMC6"	"hsa:83460; Q9BV81"	""	""	"0"	"0"	"8.8"	"2.5"	"8.0"	"4.7"	"6.4"	"10.4"	"5.4"	"9.6"	"11.8"	"24.2"	"45.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6Y7W6"	"GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1299"	"150.0"	"5.54"	"386.45"	"3.63"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf02213"	"26058"	"ENSG00000204120"	"GIGYF2"	"A6H8W4; B9EG55; E9PBB0; hsa:26058; O75137; Q6Y7W6; Q7Z2Z8; Q7Z3I2; Q96HU4; Q9NV82"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"27.2"	"11.7"	"24.5"	"20.2"	"25.7"	"28.6"	"21.3"	"28.0"	"17.2"	"34.1"	"58.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96J84"	"Kin of IRRE-like protein 1 OS=Homo sapiens OX=9606 GN=KIRREL1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"757"	"83.5"	"5.73"	"340.96"	"3.62"	"1"	"1"	"cell adhesion;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;other cell component"	"cytoskeletal activity;other molecular function"	"Pf07679, Pf08205, Pf13927"	"55243"	"ENSG00000183853"	"KIRREL1"	"hsa:55243; Q5W0F8; Q5XKC6; Q7Z696; Q7Z7N8; Q8TB15; Q96J84; Q9H9N1; Q9NVA5"	"Nephrin family interactions"	"Genes controlling nephrogenesis; 1q21.1 copy number variation syndrome"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14880"	"Microsomal glutathione S-transferase 3 OS=Homo sapiens OX=9606 GN=MGST3 PE=1 SV=1"	"0.000"	""	"9"	"1"	"2"	"1"	"152"	"16.5"	"9.38"	"399.69"	"3.62"	"1"	"1"	"other metabolic processes;other biological processes"	"other membranes;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf01124"	"4259"	"ENSG00000143198"	"MGST3"	"B2R592; hsa:4259; O14880; Q6ICN4"	"Aflatoxin activation and detoxification; Glutathione conjugation"	"Nuclear receptors meta-pathway; NRF2 pathway; Metapathway biotransformation Phase I and II"	"5"	"0"	"89.0"	"28.0"	"78.0"	"67.8"	"78.0"	"99.6"	"77.7"	"94.0"	"92.5"	"166.8"	"313.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EK6"	"Glucosamine 6-phosphate N-acetyltransferase OS=Homo sapiens OX=9606 GN=GNPNAT1 PE=1 SV=1"	"0.000"	""	"14"	"2"	"3"	"2"	"184"	"20.7"	"7.99"	"626.48"	"3.61"	"2"	"1"	"other metabolic processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle"	"other molecular function"	"Pf00583"	"64841"	"ENSG00000100522"	"GNPNAT1"	"hsa:64841; Q96EK6"	"Synthesis of UDP-N-acetyl-glucosamine"	""	"1"	"0"	"12.9"	"6.6"	"10.6"	"10.3"	"12.3"	"13.5"	"13.4"	"13.0"	"16.7"	"29.0"	"72.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q5HYJ3"	"Protein FAM76B OS=Homo sapiens OX=9606 GN=FAM76B PE=1 SV=3"	""	""	"3"	"1"	"1"	"1"	"339"	"38.7"	"9.25"	""	"3.61"	""	"1"	""	"nucleus"	""	"Pf16046"	"143684"	"ENSG00000077458"	"FAM76B"	"B2R9C2; hsa:143684; Q5HYJ3; Q6PIU3; Q8TC53"	""	""	"0"	"0"	"12.8"	"6.7"	"12.2"	"7.4"	"8.2"	"10.2"	"6.6"	"20.6"	"29.2"	"166.2"	"214.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6UB35"	"Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"978"	"105.7"	"8.06"	"400.03"	"3.61"	"1"	"1"	"other metabolic processes;developmental processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf00763, Pf01268, Pf02882"	"25902"	"ENSG00000120254"	"MTHFD1L"	"hsa:25902; Q2TBF3; Q6UB35; Q8WVW0; Q96HG8; Q9H789; Q9UFU8"	"Metabolism of folate and pterines"	"One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways"	"3"	"0"	"51.5"	"20.9"	"48.5"	"39.3"	"48.6"	"49.9"	"39.9"	"46.3"	"40.4"	"79.4"	"134.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99714"	"3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3"	"0.000"	""	"5"	"1"	"2"	"1"	"261"	"26.9"	"7.78"	"375.21"	"3.60"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00106"	"3028"	"ENSG00000072506"	"HSD17B10"	"hsa:3028; Q5H927; Q6IBS9; Q8TCV9; Q96HD5; Q99714"	"Branched-chain amino acid catabolism; tRNA processing in the mitochondrion; tRNA modification in the mitochondrion; rRNA processing in the mitochondrion"	"Alzheimer's disease and miRNA effects; Valproic acid pathway; Alzheimer's disease"	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4P3"	"Transducin beta-like protein 2 OS=Homo sapiens OX=9606 GN=TBL2 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"447"	"49.8"	"9.44"	"566.47"	"3.60"	"1"	"1"	"stress response;signal transduction"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00400"	"26608"	"ENSG00000106638"	"TBL2"	"hsa:26608; Q9UQE2; Q9Y4P3"	""	"7q11.23 copy number variation syndrome"	"1"	"0"	"16.4"	"5.1"	"16.2"	"15.1"	"13.1"	"17.1"	"12.8"	"14.6"	"11.4"	"26.2"	"88.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14137"	"Ribosome biogenesis protein BOP1 OS=Homo sapiens OX=9606 GN=BOP1 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"746"	"83.6"	"6.19"	"305.26"	"3.58"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00400, Pf08145"	"23246"	"ENSG00000261236; ENSG00000285301"	"BOP1"	"hsa:23246; Q14137; Q969Z6; Q96IS8; Q96Q25; Q9BSA7; Q9BVM0"	"Major pathway of rRNA processing in the nucleolus and cytosol"	""	"1"	"0"	"14.0"	"12.6"	"20.9"	"23.8"	"21.4"	"26.2"	"18.3"	"14.6"	"11.9"	"20.5"	"20.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NYJ1"	"Cytochrome c oxidase assembly factor 4 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=COA4 PE=1 SV=2"	"0.000"	""	"20"	"2"	"3"	"2"	"87"	"10.1"	"6.04"	"927.69"	"3.58"	"2"	"1"	"cell organization and biogenesis"	"mitochondrion"	""	""	"51287"	"ENSG00000181924"	"COA4"	"B2RAA0; hsa:51287; Q69YU4; Q9NYJ1"	"Mitochondrial protein import"	""	"1"	"0"	"105.7"	"48.7"	"111.7"	"117.3"	"124.9"	"148.4"	"104.0"	"149.0"	"76.0"	"155.6"	"204.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P78346"	"Ribonuclease P protein subunit p30 OS=Homo sapiens OX=9606 GN=RPP30 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"268"	"29.3"	"8.91"	"356.54"	"3.57"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01876"	"10556"	"ENSG00000148688"	"RPP30"	"B2R799; E9PB02; hsa:10556; P78346"	"Major pathway of rRNA processing in the nucleolus and cytosol; tRNA processing in the nucleus"	""	"2"	"0"	"21.0"	"14.9"	"19.5"	"15.7"	"16.7"	"22.2"	"17.6"	"23.7"	"22.5"	"42.4"	"67.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UPQ9"	"Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens OX=9606 GN=TNRC6B PE=1 SV=4"	""	""	"1"	"1"	"1"	"1"	"1833"	"193.9"	"6.76"	""	"3.56"	""	"1"	"other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf10427, Pf16608"	"23112"	"ENSG00000100354"	"TNRC6B"	"B0QY73; B0QY78; B4DGC0; hsa:23112; Q5TH52; Q8TBX2; Q9UPQ9"	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux; Oxidative Stress Induced Senescence; MAPK6/MAPK4 signaling; Estrogen-dependent gene expression; Pre-NOTCH Transcription and Translation; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; TP53 Regulates Metabolic Genes; Oncogene Induced Senescence; Transcriptional Regulation by VENTX; Ca2+ pathway; Regulation of MECP2 expression and activity; Regulation of RUNX1 Expression and Activity; Regulation of CDH11 mRNA translation by microRNAs; Regulation of NPAS4 mRNA translation; Post-transcriptional silencing by small RNAs; Competing endogenous RNAs (ceRNAs) regulate PTEN translation"	""	"18"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9GZR7"	"ATP-dependent RNA helicase DDX24 OS=Homo sapiens OX=9606 GN=DDX24 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"859"	"96.3"	"9.06"	"352.58"	"3.56"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00270, Pf00271"	"57062"	"ENSG00000089737; ENSG00000273761"	"DDX24"	"E7EMJ4; hsa:57062; Q4V9L5; Q9GZR7"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63272"	"Transcription elongation factor SPT4 OS=Homo sapiens OX=9606 GN=SUPT4H1 PE=1 SV=1"	"0.001"	""	"14"	"1"	"2"	"1"	"117"	"13.2"	"8.06"	"290.48"	"3.54"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf06093"	"6827"	"ENSG00000213246"	"SUPT4H1"	"B2R4X8; D3DTZ4; hsa:6827; P63272; Q16550; Q62387; Q6ZP89"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes"	"Initiation of transcription and translation elongation at the HIV-1 LTR"	"16"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96AY3"	"Peptidyl-prolyl cis-trans isomerase FKBP10 OS=Homo sapiens OX=9606 GN=FKBP10 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"582"	"64.2"	"5.62"	"439.68"	"3.53"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes"	"other membranes;mitochondrion;ER/Golgi"	"other molecular function"	"Pf00254, Pf13202"	"60681"	"ENSG00000141756"	"FKBP10"	"hsa:60681; Q7Z3R4; Q96AY3; Q9H3N3; Q9H6J3; Q9H6N5; Q9UF89"	""	"Type I collagen synthesis in the context of osteogenesis imperfecta"	"1"	"0"	"48.2"	"22.4"	"37.8"	"30.1"	"34.2"	"34.9"	"29.4"	"35.5"	"41.1"	"42.6"	"88.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H0G5"	"Nuclear speckle splicing regulatory protein 1 OS=Homo sapiens OX=9606 GN=NSRP1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"558"	"66.4"	"8.84"	"421.38"	"3.52"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf09745, Pf20427"	"84081"	"ENSG00000126653"	"NSRP1"	"hsa:84081; Q6FI71; Q9H0G5"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"156.4"	"61.0"	"114.9"	"124.3"	"133.3"	"151.2"	"129.9"	"196.8"	"151.9"	"238.3"	"352.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00231"	"26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3"	"0.000"	""	"7"	"3"	"4"	"3"	"422"	"47.4"	"6.48"	"975.52"	"3.52"	"3"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf01399, Pf18055, Pf18503"	"5717"	"ENSG00000108671"	"PSMD11"	"A8K3I7; E1P663; hsa:5717; O00231; O00495; Q53FT5"	"Separation of Sister Chromatids; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Parkin-ubiquitin proteasomal system pathway; VEGFA-VEGFR2 signaling"	"63"	"0"	"460.0"	"191.5"	"380.7"	"339.3"	"387.8"	"455.4"	"348.8"	"404.0"	"307.5"	"459.6"	"788.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9GZR2"	"RNA exonuclease 4 OS=Homo sapiens OX=9606 GN=REXO4 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"422"	"46.6"	"9.77"	"337.16"	"3.52"	"1"	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00929"	"57109"	"ENSG00000148300; ENSG00000280706"	"REXO4"	"B2RAT2; hsa:57109; Q5T8S4; Q5T8S5; Q5T8S6; Q9GZR2; Q9GZW3"	""	""	"0"	"0"	"49.9"	"26.9"	"50.2"	"45.4"	"51.9"	"57.1"	"46.7"	"61.5"	"80.5"	"283.5"	"451.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96IZ7"	"Serine/Arginine-related protein 53 OS=Homo sapiens OX=9606 GN=RSRC1 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"334"	"38.7"	"11.08"	"382.98"	"3.51"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	""	""	"51319"	"ENSG00000174891"	"RSRC1"	"A8K2R9; hsa:51319; Q96IZ7; Q96QK2; Q9NZE5"	""	""	"0"	"0"	"25.4"	"12.3"	"24.4"	"20.2"	"23.2"	"22.2"	"21.4"	"31.5"	"27.1"	"59.5"	"97.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q07065"	"Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2"	"0.000"	""	"4"	"2"	"3"	"2"	"602"	"66.0"	"5.92"	"600.34"	"3.51"	"2"	"1"	""	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	""	""	"10970"	"ENSG00000136026"	"CKAP4"	"hsa:10970; Q07065; Q504S5; Q53ES6"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Neutrophil degranulation; RND2 GTPase cycle; RND3 GTPase cycle; Surfactant metabolism"	""	"6"	"0"	"160.6"	"53.1"	"134.1"	"107.7"	"123.9"	"160.3"	"106.1"	"145.2"	"118.3"	"260.1"	"495.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BW85"	"Splicing factor YJU2 OS=Homo sapiens OX=9606 GN=YJU2 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"323"	"37.1"	"5.92"	"458.38"	"3.50"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf04502"	"55702"	"ENSG00000105248"	"YJU2"	"hsa:55702; O75270; Q9BW85; Q9H862; Q9NW16"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"30.8"	"14.1"	"32.2"	"31.6"	"33.1"	"42.5"	"24.0"	"47.7"	"28.2"	"47.9"	"86.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P61163"	"Alpha-centractin OS=Homo sapiens OX=9606 GN=ACTR1A PE=1 SV=1"	""	""	"6"	"1"	"1"	"1"	"376"	"42.6"	"6.64"	""	"3.50"	""	"1"	"transport"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00022"	"10121"	"ENSG00000138107"	"ACTR1A"	"B2R6B0; hsa:10121; P42024; P61163"	"COPI-mediated anterograde transport; Anchoring of the basal body to the plasma membrane; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; MHC class II antigen presentation; Recruitment of NuMA to mitotic centrosomes; COPI-independent Golgi-to-ER retrograde traffic; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; AURKA Activation by TPX2"	""	"11"	"0"	"14.7"	"7.5"	"11.5"	"12.9"	"12.6"	"14.7"	"9.4"	"17.1"	"16.4"	"26.1"	"46.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05091"	"Aldehyde dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH2 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"517"	"56.3"	"7.05"	"349.52"	"3.49"	"1"	"1"	"other metabolic processes;other biological processes"	"mitochondrion"	"other molecular function"	"Pf00171"	"217"	"ENSG00000111275"	"ALDH2"	"B4DW54; E7EUE5; hsa:217; P05091; Q03639; Q6IB13; Q6IV71"	"Smooth Muscle Contraction; Ethanol oxidation; Metabolism of serotonin"	"Fatty acid omega-oxidation; Ethanol effects on histone modifications; Tryptophan metabolism; Fluoroacetic acid toxicity"	"7"	"0"	"14.6"	"5.1"	"15.1"	"8.7"	"13.6"	"15.7"	"7.6"	"16.3"	"14.7"	"24.8"	"40.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49642"	"DNA primase small subunit OS=Homo sapiens OX=9606 GN=PRIM1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"3"	"1"	"420"	"49.9"	"8.21"	"605.10"	"3.49"	"1"	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf01896"	"5557"	"ENSG00000198056"	"PRIM1"	"hsa:5557; P49642"	"Polymerase switching on the C-strand of the telomere; Polymerase switching; Removal of the Flap Intermediate; Activation of the pre-replicative complex; Defective pyroptosis; Inhibition of replication initiation of damaged DNA by RB1/E2F1; Telomere C-strand synthesis initiation; DNA replication initiation"	"Retinoblastoma gene in cancer; Pyrimidine metabolism; G1 to S cell cycle control; DNA replication"	"13"	"0"	"23.6"	"13.7"	"23.0"	"23.2"	"17.1"	"27.7"	"25.3"	"27.6"	"24.5"	"43.8"	"101.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53999"	"Activated RNA polymerase II transcriptional coactivator p15 OS=Homo sapiens OX=9606 GN=SUB1 PE=1 SV=3"	"0.000"	""	"10"	"1"	"2"	"1"	"127"	"14.4"	"9.60"	"332.41"	"3.48"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02229"	"10923"	"ENSG00000113387"	"SUB1"	"hsa:10923; P53999; Q96L29"	""	""	"0"	"0"	"56.7"	"31.8"	"62.5"	"57.6"	"46.6"	"81.2"	"71.0"	"137.5"	"123.5"	"157.8"	"125.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00193"	"Small acidic protein OS=Homo sapiens OX=9606 GN=SMAP PE=1 SV=1"	"0.000"	""	"8"	"2"	"3"	"2"	"183"	"20.3"	"4.72"	"600.70"	"3.48"	"2"	"1"	""	""	""	"Pf15477"	"10944"	"ENSG00000110696"	"SMAP"	"B2RD28; hsa:10944; O00193"	""	""	"0"	"0"	"387.0"	"184.6"	"437.8"	"421.2"	"473.8"	"648.3"	"486.9"	"726.2"	"374.5"	"582.7"	"842.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q13155"	"Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 OS=Homo sapiens OX=9606 GN=AIMP2 PE=1 SV=2"	""	""	"4"	"1"	"1"	"1"	"320"	"35.3"	"8.22"	""	"3.48"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf14497, Pf16780, Pf18569"	"7965"	"ENSG00000106305"	"AIMP2"	"F8W950; hsa:7965; Q13155; Q75MR1; Q96CZ5; Q9P1L2"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"Osteoclast signaling; Transcriptional activation by NRF2 in response to phytochemicals; NRF2-ARE regulation"	"5"	"0"	"6.5"	"3.5"	"3.9"	"5.5"	"5.0"	"8.9"	"6.6"	"13.6"	"11.1"	"30.0"	"136.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NVM9"	"Integrator complex subunit 13 OS=Homo sapiens OX=9606 GN=INTS13 PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"706"	"80.2"	"6.70"	""	"3.48"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf10221"	"55726"	"ENSG00000064102"	"INTS13"	"B4DNK1; hsa:55726; Q86WE2; Q96HM2; Q9BTX2; Q9NTB6; Q9NVM5; Q9NVM9"	"RNA polymerase II transcribes snRNA genes"	"1p36 copy number variation syndrome"	"2"	"0"	"10.3"	"3.2"	"3.4"	"6.2"	"7.9"	"9.0"	"6.6"	"7.7"	"11.1"	"22.2"	"51.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23743"	"Diacylglycerol kinase alpha OS=Homo sapiens OX=9606 GN=DGKA PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"735"	"82.6"	"6.73"	"346.85"	"3.47"	"1"	"1"	"other metabolic processes;stress response;signal transduction"	"plasma membrane;other membranes;cytosol"	"kinase activity;other molecular function"	"Pf00130, Pf00609, Pf00781, Pf14513"	"1606"	"ENSG00000065357"	"DGKA"	"hsa:1606; O75481; O75482; O75483; O95217; P23743; Q3ZE25; Q8IZ56; Q8N5Q2"	"Effects of PIP2 hydrolysis"	"Modulators of TCR signaling and T cell activation"	"2"	"0"	"8.3"	"2.1"	"6.3"	"7.3"	"7.5"	"9.5"	"7.3"	"7.9"	"12.1"	"25.7"	"57.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P16615"	"Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2A2 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1042"	"114.7"	"5.34"	"381.03"	"3.47"	"1"	"1"	"cell adhesion;cell organization and biogenesis;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"transporter activity;other molecular function"	"Pf00122, Pf00689, Pf00690, Pf08282, Pf13246"	"488"	"ENSG00000174437"	"ATP2A2"	"A6NDN7; B4DF05; hsa:488; P16614; P16615; Q86VJ2"	"Ion homeostasis; Ion transport by P-type ATPases; Pre-NOTCH Processing in Golgi; Reduction of cytosolic Ca++ levels"	"Alzheimer's disease and miRNA effects; Arrhythmogenic right ventricular cardiomyopathy; Endothelin pathways; Myometrial relaxation and contraction pathways; Alzheimer's disease; Calcium regulation in cardiac cells"	"10"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P60903"	"Protein S100-A10 OS=Homo sapiens OX=9606 GN=S100A10 PE=1 SV=2"	"0.000"	""	"18"	"1"	"2"	"1"	"97"	"11.2"	"7.37"	"558.61"	"3.47"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf01023"	"6281"	"ENSG00000197747"	"S100A10"	"A8K4V8; hsa:6281; P08206; P60903; Q5T1C5"	"Dissolution of Fibrin Clot"	"8p23.1 copy number variation syndrome; Prostaglandin synthesis and regulation"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P29372"	"DNA-3-methyladenine glycosylase OS=Homo sapiens OX=9606 GN=MPG PE=1 SV=3"	"0.000"	""	"5"	"1"	"2"	"1"	"298"	"32.8"	"9.57"	"337.27"	"3.46"	"1"	"1"	"DNA metabolism;other metabolic processes;stress response"	"cytosol;mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf02245"	"4350"	"ENSG00000103152"	"MPG"	"G5E9E2; hsa:4350; P29372; Q13770; Q15275; Q15961; Q5J9I4; Q96BZ6; Q96S33; Q9NNX5"	"Recognition and association of DNA glycosylase with site containing an affected purine; Cleavage of the damaged purine; Displacement of DNA glycosylase by APEX1"	"Base excision repair; DNA repair pathways, full network"	"5"	"0"	"21.4"	"13.2"	"24.3"	"18.3"	"23.3"	"25.5"	"22.7"	"26.4"	"18.4"	"46.8"	"85.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75348"	"V-type proton ATPase subunit G 1 OS=Homo sapiens OX=9606 GN=ATP6V1G1 PE=1 SV=3"	"0.000"	""	"9"	"1"	"2"	"1"	"118"	"13.7"	"8.79"	"438.61"	"3.44"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf03179"	"9550"	"ENSG00000136888"	"ATP6V1G1"	"hsa:9550; O75348; Q6IB33"	"Amino acids regulate mTORC1; ROS and RNS production in phagocytes; Insulin receptor recycling; Transferrin endocytosis and recycling; Ion channel transport"	"Osteoclast signaling; Proximal tubule transport"	"7"	"0"	"228.7"	"131.3"	"182.8"	"154.8"	"172.8"	"193.3"	"146.0"	"181.1"	"161.9"	"254.8"	"347.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P17252"	"Protein kinase C alpha type OS=Homo sapiens OX=9606 GN=PRKCA PE=1 SV=4"	"0.000"	""	"2"	"1"	"2"	"1"	"672"	"76.7"	"7.05"	"386.72"	"3.43"	"1"	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf00069, Pf00130, Pf00168, Pf00433"	"5578"	"ENSG00000154229"	"PRKCA"	"B5BU22; hsa:5578; P17252; Q15137; Q32M72; Q96RE4"	"G alpha (z) signalling events; Disinhibition of SNARE formation; RET signaling; Regulation of KIT signaling; SHC1 events in ERBB2 signaling; Ca2+ pathway; WNT5A-dependent internalization of FZD4; Inactivation, recovery and regulation of the phototransduction cascade; Syndecan interactions; HuR (ELAVL1) binds and stabilizes mRNA; VEGFR2 mediated cell proliferation; Trafficking of GluR2-containing AMPA receptors; Depolymerization of the Nuclear Lamina; Acetylcholine regulates insulin secretion; EGFR Transactivation by Gastrin; RHO GTPases Activate NADPH Oxidases; Calmodulin induced events; ROBO receptors bind AKAP5"	"Target of rapamycin signaling; Thyroxine (thyroid hormone) production; Follicle stimulating hormone (FSH) signaling pathway; Microtubule cytoskeleton regulation; Endothelin pathways; Glioblastoma signaling pathways; Pathogenic Escherichia coli infection; AGE/RAGE pathway; Corticotropin-releasing hormone signaling pathway; Oncostatin M signaling pathway; Spinal cord injury; Alpha 6 beta 4 signaling pathway; T cell receptor and co-stimulatory signaling; Common pathways underlying drug addiction; Cardiac hypertrophic response; Complement system; Myometrial relaxation and contraction pathways; Transcriptional activation by NRF2 in response to phytochemicals; Kit receptor signaling pathway; Focal adhesion; Melatonin metabolism and effects; G protein signaling pathways; Wnt signaling pathway; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Wnt signaling pathway and pluripotency; PI3K-Akt signaling pathway; Ras signaling; Non-small cell lung cancer; Wnt signaling; Non-genomic actions of 1,25 dihydroxyvitamin D3; NRF2-ARE regulation; EGF/EGFR signaling pathway; Hippo signaling regulation pathways; Fragile X syndrome; Overview of interferons-mediated signaling pathway; Translation inhibitors in chronically activated PDGFRA cells; Gastrin signaling pathway; Hepatitis B infection; Netrin-UNC5B signaling pathway; IL-18 signaling pathway; Osteoblast differentiation and related diseases; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; Kisspeptin/kisspeptin receptor system in the ovary; Neuroinflammation and glutamatergic signaling; Orexin receptor pathway; Hippocampal synaptogenesis and neurogenesis; Chronic hyperglycemia impairment of neuron function; TROP2 regulatory signaling; Cardiomyocyte signaling pathways converging on Titin; Calcium regulation in cardiac cells; Role of hypoxia, angiogenesis, and FGF pathway in OA chondrocyte hypertrophy; ErbB signaling pathway"	"74"	"0"	"19.5"	"11.4"	"19.1"	"17.0"	"23.1"	"26.4"	"15.6"	"25.7"	"16.6"	"42.8"	"77.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P38432"	"Coilin OS=Homo sapiens OX=9606 GN=COIL PE=1 SV=1"	"0.000"	""	"3"	"2"	"3"	"2"	"576"	"62.6"	"9.07"	"642.92"	"3.43"	"2"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf15862"	"8161"	"ENSG00000121058"	"COIL"	"B2R931; hsa:8161; P38432"	""	""	"0"	"0"	"128.9"	"58.4"	"101.1"	"94.9"	"94.2"	"113.3"	"124.7"	"199.9"	"211.1"	"942.8"	"1564.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43181"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS4 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"175"	"20.1"	"10.30"	"394.97"	"3.41"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;mitochondrion"	"transporter activity"	"Pf04800"	"4724"	"ENSG00000164258"	"NDUFS4"	"hsa:4724; O43181; Q9BS69"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"5"	"0"	"335.6"	"101.2"	"244.6"	"176.4"	"248.8"	"270.5"	"201.8"	"306.8"	"240.9"	"722.7"	"1820.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P36915"	"Guanine nucleotide-binding protein-like 1 OS=Homo sapiens OX=9606 GN=GNL1 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"607"	"68.6"	"5.80"	"417.70"	"3.41"	"1"	"1"	"stress response;signal transduction;other biological processes"	"non-structural extracellular"	"other molecular function"	"Pf01926"	"2794"	"ENSG00000204590; ENSG00000206492; ENSG00000226882; ENSG00000228581; ENSG00000229470; ENSG00000232143; ENSG00000235986"	"GNL1"	"B0S838; hsa:2794; P36915; Q96CT5"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NS69"	"Mitochondrial import receptor subunit TOM22 homolog OS=Homo sapiens OX=9606 GN=TOMM22 PE=1 SV=3"	"0.000"	""	"8"	"1"	"2"	"1"	"142"	"15.5"	"4.34"	"348.47"	"3.39"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity"	"Pf04281"	"56993"	"ENSG00000100216"	"TOMM22"	"hsa:56993; Q9NS69"	"PINK1-PRKN Mediated Mitophagy; Mitochondrial protein import"	""	"2"	"0"	"56.0"	"17.6"	"46.6"	"35.5"	"40.1"	"50.5"	"40.9"	"53.1"	"46.2"	"93.0"	"155.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15532"	"Protein SSXT OS=Homo sapiens OX=9606 GN=SS18 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"418"	"45.9"	"6.46"	"515.07"	"3.39"	"1"	"1"	"cell organization and biogenesis;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf05030"	"6760"	"ENSG00000141380"	"SS18"	"B0YJ95; hsa:6760; Q15532; Q16404; Q4VAX1; Q9BXC6"	""	""	"0"	"0"	"42.4"	"23.4"	"57.7"	"42.3"	"45.2"	"45.6"	"38.1"	"49.4"	"32.9"	"51.0"	"45.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQ15"	"SOSS complex subunit B1 OS=Homo sapiens OX=9606 GN=NABP2 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"211"	"22.3"	"9.06"	"376.18"	"3.39"	"1"	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01336"	"79035"	"ENSG00000139579"	"NABP2"	"A6NDF8; hsa:79035; Q6XYC8; Q9BQ15"	"RNA polymerase II transcribes snRNA genes"	"Mesodermal commitment pathway"	"2"	"0"	"23.9"	"8.4"	"23.6"	"28.3"	"26.8"	"33.6"	"21.1"	"31.5"	"19.9"	"34.0"	"65.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15050"	"Ribosome biogenesis regulatory protein homolog OS=Homo sapiens OX=9606 GN=RRS1 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"365"	"41.2"	"10.70"	"326.87"	"3.38"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity"	"Pf04939"	"23212"	"ENSG00000179041"	"RRS1"	"hsa:23212; Q15050; Q9BUX8"	""	""	"0"	"0"	"54.3"	"17.0"	"41.8"	"37.3"	"38.3"	"51.9"	"32.7"	"61.0"	"30.3"	"97.8"	"195.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BRJ6"	"Uncharacterized protein C7orf50 OS=Homo sapiens OX=9606 GN=C7orf50 PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"194"	"22.1"	"9.64"	"382.94"	"3.38"	"1"	"1"	""	""	""	"Pf10180"	"84310"	"ENSG00000146540"	"C7orf50"	"hsa:84310; Q9BRJ6"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H501"	"ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"851"	"98.7"	"5.11"	"395.84"	"3.38"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf08159"	"51575"	"ENSG00000089048"	"ESF1"	"hsa:51575; Q86X92; Q9H501; Q9H9Q5; Q9HA35; Q9NX93; Q9P1S6"	""	""	"0"	"0"	"14.4"	"7.0"	"12.9"	"8.7"	"15.6"	"14.8"	"14.6"	"13.9"	"14.3"	"40.3"	"93.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62873"	"Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 OS=Homo sapiens OX=9606 GN=GNB1 PE=1 SV=3"	"0.001"	""	"3"	"1"	"2"	"1"	"340"	"37.4"	"6.00"	"264.72"	"3.38"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00400"	"2782"	"ENSG00000078369"	"GNB1"	"B1AJZ7; hsa:2782; P04697; P04901; P62873; Q1RMY8"	"G alpha (q) signalling events; G alpha (12/13) signalling events; Olfactory Signaling Pathway; G alpha (i) signalling events; G alpha (z) signalling events; Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1); ADP signalling through P2Y purinoceptor 12; Extra-nuclear estrogen signaling; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; Sensory perception of sweet, bitter, and umami (glutamate) taste; Thrombin signalling through proteinase activated receptors (PARs); Activation of G protein gated Potassium channels; G-protein activation; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; G beta:gamma signalling through PI3Kgamma; Prostacyclin signalling through prostacyclin receptor; Adrenaline,noradrenaline inhibits insulin secretion; Ca2+ pathway; G beta:gamma signalling through PLC beta; ADP signalling through P2Y purinoceptor 1; Glucagon-type ligand receptors; Thromboxane signalling through TP receptor; Vasopressin regulates renal water homeostasis via Aquaporins; Presynaptic function of Kainate receptors; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; G beta:gamma signalling through BTK; G beta:gamma signalling through CDC42; Inhibition  of voltage gated Ca2+ channels via Gbeta/gamma subunits; Inactivation, recovery and regulation of the phototransduction cascade; Glucagon signaling in metabolic regulation; Activation of the phototransduction cascade"	"Nicotine effect on dopaminergic neurons; Thyroid stimulating hormone (TSH) signaling pathway; Corticotropin-releasing hormone signaling pathway; Myometrial relaxation and contraction pathways; G protein signaling pathways; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Ras signaling; 1p36 copy number variation syndrome; Calcium regulation in cardiac cells; Estrogen signaling pathway"	"45"	"0"	"87.2"	"32.0"	"51.6"	"44.1"	"54.9"	"70.9"	"55.2"	"70.3"	"69.9"	"130.9"	"211.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q08209"	"Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform OS=Homo sapiens OX=9606 GN=PPP3CA PE=1 SV=1"	"0.001"	""	"2"	"1"	"2"	"1"	"521"	"58.7"	"5.86"	"282.76"	"3.38"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00149"	"5530"	"ENSG00000138814"	"PPP3CA"	"A1A441; A8K3B7; A8W6Z7; A8W6Z8; B5BUA2; hsa:5530; Q08209; Q8TAW9"	"DARPP-32 events; FCERI mediated Ca+2 mobilization; Ca2+ pathway; CLEC7A (Dectin-1) induces NFAT activation; Calcineurin activates NFAT"	"Physiological and pathological hypertrophy of the heart; Energy metabolism; MicroRNAs in cardiomyocyte hypertrophy; Alzheimer's disease and miRNA effects; Spinal cord injury; Amyotrophic lateral sclerosis (ALS); T cell receptor and co-stimulatory signaling; Cardiac hypertrophic response; Initiation of transcription and translation elongation at the HIV-1 LTR; G protein signaling pathways; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Mitochondrial gene expression; Serotonin and anxiety-related events; Serotonin and anxiety; Wnt signaling; Vitamin D in inflammatory diseases; Fragile X syndrome; Alzheimer's disease; Th17 cell differentiation pathway"	"25"	"0"	"124.0"	"55.7"	"107.4"	"101.3"	"100.7"	"108.5"	"86.8"	"100.6"	"75.6"	"106.7"	"156.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L2H7"	"Eukaryotic translation initiation factor 3 subunit M OS=Homo sapiens OX=9606 GN=EIF3M PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"374"	"42.5"	"5.63"	"362.13"	"3.38"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01399, Pf18005"	"10480"	"ENSG00000149100"	"EIF3M"	"A8K7X4; B4E2Q4; hsa:10480; O60735; Q2F836; Q53HL6; Q7L2H7; Q9BXW1"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	""	"6"	"0"	"37.7"	"19.0"	"47.8"	"40.4"	"37.1"	"49.9"	"37.3"	"40.9"	"32.6"	"63.7"	"95.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q66PJ3"	"ADP-ribosylation factor-like protein 6-interacting protein 4 OS=Homo sapiens OX=9606 GN=ARL6IP4 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"421"	"44.9"	"10.93"	"300.85"	"3.37"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"90.2"	"40.7"	"79.7"	"63.7"	"73.7"	"90.4"	"79.2"	"123.3"	"108.1"	"200.6"	"299.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H0U3"	"Magnesium transporter protein 1 OS=Homo sapiens OX=9606 GN=MAGT1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"335"	"38.0"	"9.63"	"381.24"	"3.36"	"1"	"1"	"protein metabolism;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle"	"transporter activity"	"Pf04756"	"84061"	"ENSG00000102158"	"MAGT1"	"B2RAR4; D3DTE3; hsa:84061; Q53G00; Q6P577; Q8NBN6; Q9H0U3"	"Neutrophil degranulation; Miscellaneous transport and binding events; Asparagine N-linked glycosylation; Maturation of spike protein"	""	"4"	"0"	"15.2"	"6.9"	"12.9"	"10.2"	"14.3"	"13.7"	"8.8"	"15.4"	"18.6"	"31.3"	"66.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13405"	"39S ribosomal protein L49, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL49 PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"166"	"19.2"	"9.45"	"348.15"	"3.35"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf05046"	"740"	"ENSG00000149792"	"MRPL49"	"B2R4G6; hsa:740; Q13405"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"69.3"	"23.4"	"64.7"	"48.4"	"58.6"	"69.0"	"55.4"	"62.5"	"46.0"	"81.2"	"240.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O96019"	"Actin-like protein 6A OS=Homo sapiens OX=9606 GN=ACTL6A PE=1 SV=1"	"0.001"	""	"3"	"1"	"2"	"1"	"429"	"47.4"	"5.60"	"287.25"	"3.35"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00022"	"86"	"ENSG00000136518"	"ACTL6A"	"B3KMN1; D3DNR9; hsa:86; O96019; Q8TAE5; Q9BVS8; Q9H0W6"	"UCH proteinases; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; RMTs methylate histone arginines; HATs acetylate histones; DNA Damage Recognition in GG-NER"	"Androgen receptor network in prostate cancer; Gastric cancer network 1; Tumor suppressor activity of SMARCB1; Thermogenesis; Kleefstra syndrome"	"10"	"0"	"55.2"	"21.8"	"47.9"	"32.6"	"38.7"	"42.6"	"39.2"	"52.2"	"36.1"	"71.6"	"134.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BZ95"	"Histone-lysine N-methyltransferase NSD3 OS=Homo sapiens OX=9606 GN=NSD3 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1437"	"161.5"	"8.21"	"317.43"	"3.34"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00855, Pf00856, Pf17907, Pf17982"	"54904"	"ENSG00000147548"	"NSD3"	"B7ZL11; D3DSX1; hsa:54904; Q1RMD3; Q3B796; Q6ZSA5; Q9BYU8; Q9BYU9; Q9BZ95; Q9H2M8; Q9H9W9; Q9NXA6"	"PKMTs methylate histone lysines"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y223"	"Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase OS=Homo sapiens OX=9606 GN=GNE PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"722"	"79.2"	"6.80"	"328.92"	"3.34"	"1"	"1"	"cell adhesion;other metabolic processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00480, Pf02350"	"10020"	"ENSG00000159921"	"GNE"	"A6PZH2; A6PZH3; A7UNU7; B2R6E1; B7Z372; B7Z428; D3DRP7; F5H499; H0YFA7; hsa:10020; Q0VA94; Q9Y223"	"Sialic acid metabolism; Defective GNE causes sialuria, NK and IBM2"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43670"	"BUB3-interacting and GLEBS motif-containing protein ZNF207 OS=Homo sapiens OX=9606 GN=ZNF207 PE=1 SV=1"	"0.000"	""	"4"	"2"	"3"	"2"	"478"	"50.7"	"9.10"	"654.31"	"3.34"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	""	"7756"	"ENSG00000010244"	"ZNF207"	"A8K6Y6; E1P660; E1P661; E1P662; hsa:7756; O43670; Q53XS9; Q96HW5; Q9BUQ7"	""	""	"0"	"0"	"328.9"	"80.7"	"274.9"	"218.2"	"269.8"	"319.2"	"179.9"	"317.0"	"205.2"	"853.1"	"1621.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q6N069"	"N-alpha-acetyltransferase 16, NatA auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA16 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"864"	"101.4"	"7.87"	""	"3.34"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity"	"Pf07719, Pf12569"	"79612"	"ENSG00000172766"	"NAA16"	"B0QZ59; hsa:79612; Q5VSP9; Q6N069; Q6P2D5; Q8N5J3; Q8N870"	""	""	"0"	"0"	"5.2"	"0.0"	"3.7"	"2.0"	"4.2"	"2.9"	"5.9"	"4.7"	"13.2"	"72.9"	"367.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NZ32"	"Actin-related protein 10 OS=Homo sapiens OX=9606 GN=ACTR10 PE=1 SV=1"	"0.001"	""	"5"	"1"	"2"	"1"	"417"	"46.3"	"7.37"	"241.97"	"3.33"	"1"	"1"	"transport"	"non-structural extracellular;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	""	"Pf00022"	"55860"	"ENSG00000131966"	"ACTR10"	"hsa:55860; Q9H9Y5; Q9NWY2; Q9NZ32"	"MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Neutrophil degranulation"	""	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IVH8"	"Mitogen-activated protein kinase kinase kinase kinase 3 OS=Homo sapiens OX=9606 GN=MAP4K3 PE=1 SV=1"	"0.001"	""	"1"	"1"	"2"	"1"	"894"	"101.3"	"7.56"	"292.21"	"3.33"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00780"	"8491"	"ENSG00000011566"	"MAP4K3"	"hsa:8491; Q6IQ39; Q8IVH7; Q8IVH8; Q9UDM5; Q9Y6R5"	""	"MAPK signaling pathway; Angiopoietin-like protein 8 regulatory pathway; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-YAP signaling; Insulin signaling; Pleural mesothelioma"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9GZN1"	"Actin-related protein 6 OS=Homo sapiens OX=9606 GN=ACTR6 PE=1 SV=1"	"0.001"	""	"3"	"1"	"2"	"1"	"396"	"45.8"	"5.03"	"286.84"	"3.33"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00022"	"64431"	"ENSG00000075089"	"ACTR6"	"B3KW37; B4DLG9; hsa:64431; Q53GH2; Q9BY39; Q9GZN1; Q9H8H6"	""	""	"0"	"0"	"28.8"	"16.9"	"20.3"	"16.6"	"26.2"	"24.9"	"18.2"	"20.1"	"24.0"	"30.9"	"55.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95168"	"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 OS=Homo sapiens OX=9606 GN=NDUFB4 PE=1 SV=3"	"0.000"	""	"8"	"1"	"2"	"1"	"129"	"15.2"	"9.85"	"346.14"	"3.33"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;transport"	"other membranes;mitochondrion;nucleus"	"transporter activity"	"Pf07225"	"4710"	"ENSG00000065518"	"NDUFB4"	"B2RUY3; B9EJC7; hsa:4710; O95168"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"5"	"0"	"123.5"	"63.3"	"104.7"	"90.9"	"89.0"	"111.7"	"93.9"	"119.9"	"148.2"	"301.5"	"652.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96HT8"	"MORF4 family-associated protein 1-like 1 OS=Homo sapiens OX=9606 GN=MRFAP1L1 PE=1 SV=1"	"0.001"	""	"9"	"1"	"2"	"1"	"127"	"14.8"	"4.49"	"283.20"	"3.33"	"1"	"1"	""	""	"other molecular function"	"Pf15155"	"114932"	"ENSG00000178988"	"MRFAP1L1"	"B2R6R0; hsa:114932; Q6NXT8; Q96HT8; Q9P0J5"	""	""	"0"	"0"	"33.7"	"18.2"	"31.6"	"27.7"	"27.7"	"33.7"	"28.8"	"30.9"	"23.6"	"48.7"	"68.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96IZ0"	"PRKC apoptosis WT1 regulator protein OS=Homo sapiens OX=9606 GN=PAWR PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"340"	"36.5"	"5.41"	"516.19"	"3.32"	"1"	"1"	"cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	""	"5074"	"ENSG00000177425"	"PAWR"	"hsa:5074; O75796; Q6FHY9; Q8N700; Q96IZ0"	""	""	"0"	"0"	"44.7"	"20.2"	"37.0"	"30.8"	"37.1"	"35.4"	"31.4"	"35.0"	"29.9"	"47.3"	"72.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L9B9"	"Endonuclease/exonuclease/phosphatase family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=EEPD1 PE=1 SV=2"	"0.001"	""	"2"	"1"	"2"	"1"	"569"	"62.4"	"8.41"	"272.61"	"3.32"	"1"	"1"	"DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes"	"nucleic acid binding activity"	"Pf12836"	"80820"	"ENSG00000122547"	"EEPD1"	"hsa:80820; Q7L9B9; Q96K64; Q9C0F7"	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"	""	"1"	"0"	"44.3"	"16.3"	"35.5"	"41.4"	"41.1"	"40.9"	"40.6"	"66.7"	"43.4"	"108.8"	"230.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51572"	"B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3"	"0.000"	""	"4"	"1"	"2"	"1"	"246"	"28.0"	"8.44"	"368.34"	"3.32"	"1"	"1"	"cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf05529, Pf18035"	"10134"	"ENSG00000185825"	"BCAP31"	"B3KQ79; D3DWV5; hsa:10134; P51572; Q13836; Q96CF0"	"RHOA GTPase cycle; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Apoptotic cleavage of cellular proteins"	""	"4"	"0"	"179.1"	"53.7"	"112.6"	"103.2"	"121.3"	"158.4"	"143.3"	"224.2"	"148.4"	"304.6"	"537.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P29401"	"Transketolase OS=Homo sapiens OX=9606 GN=TKT PE=1 SV=3"	"0.000"	""	"4"	"2"	"3"	"2"	"623"	"67.8"	"7.66"	"632.78"	"3.32"	"2"	"1"	"other metabolic processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf00456, Pf02779, Pf02780"	"7086"	"ENSG00000163931"	"TKT"	"A8K089; B4DE31; E7EPA7; hsa:7086; P29401; Q8TBA3; Q96HH3"	"NFE2L2 regulates pentose phosphate pathway genes; Pentose phosphate pathway; Insulin effects increased synthesis of Xylulose-5-Phosphate"	"Pentose phosphate metabolism; VEGFA-VEGFR2 signaling; Metabolic reprogramming in colon cancer; Thiamine metabolic pathways"	"7"	"0"	"125.3"	"45.8"	"97.7"	"71.3"	"111.9"	"101.9"	"112.6"	"129.9"	"149.2"	"214.0"	"322.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H446"	"RWD domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RWDD1 PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"243"	"27.9"	"4.20"	"318.19"	"3.31"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"other cell component"	""	"Pf05773"	"51389"	"ENSG00000111832"	"RWDD1"	"A8K3W2; A8MT24; hsa:51389; Q9H446; Q9Y313; Q9Y6B3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16594"	"Transcription initiation factor TFIID subunit 9 OS=Homo sapiens OX=9606 GN=TAF9 PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"264"	"29.0"	"8.66"	"363.03"	"3.31"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02291"	"6880"	"ENSG00000273841; ENSG00000276463"	"TAF9"	"D3DWA3; hsa:6880; Q16594; Q5U0D1; Q9BTS1"	"HATs acetylate histones; Regulation of TP53 Activity through Phosphorylation; RNA Polymerase II Pre-transcription Events; RNA polymerase II transcribes snRNA genes; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation"	"Eukaryotic transcription initiation"	"12"	"0"	"29.5"	"13.8"	"15.8"	"20.5"	"18.2"	"16.0"	"18.9"	"24.0"	"18.6"	"35.4"	"65.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75529"	"TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L OS=Homo sapiens OX=9606 GN=TAF5L PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"589"	"66.1"	"5.88"	"470.66"	"3.31"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00400, Pf04494"	"27097"	"ENSG00000135801"	"TAF5L"	"hsa:27097; O75529; Q5TDI5; Q5TDI6; Q8IW31"	"HATs acetylate histones"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O14579"	"Coatomer subunit epsilon OS=Homo sapiens OX=9606 GN=COPE PE=1 SV=3"	""	""	"5"	"1"	"1"	"1"	"308"	"34.5"	"5.12"	""	"3.30"	""	"1"	"transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus"	"other molecular function"	"Pf04733"	"11316"	"ENSG00000105669"	"COPE"	"A6NE29; A6NKA3; hsa:11316; O14579; O76097; Q6IBB8; Q9UGP6"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport"	""	"2"	"0"	"10.0"	"8.8"	"12.7"	"10.8"	"9.6"	"12.9"	"11.8"	"11.6"	"17.9"	"21.6"	"41.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00743"	"Serine/threonine-protein phosphatase 6 catalytic subunit OS=Homo sapiens OX=9606 GN=PPP6C PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"305"	"35.1"	"5.69"	"371.49"	"3.30"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00149"	"5537"	"ENSG00000119414"	"PPP6C"	"B2R5V6; B7Z2W9; B7Z5K9; hsa:5537; O00743; Q5U0A2; Q9UIC9"	"Telomere Extension By Telomerase; COPII-mediated vesicle transport"	""	"2"	"0"	"144.4"	"64.0"	"138.2"	"131.3"	"133.7"	"169.5"	"138.2"	"168.7"	"157.8"	"263.4"	"416.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8TF76"	"Serine/threonine-protein kinase haspin OS=Homo sapiens OX=9606 GN=HASPIN PE=1 SV=3"	""	""	"3"	"1"	"1"	"1"	"798"	"88.4"	"9.16"	""	"3.29"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf12330"	"83903"	"ENSG00000177602"	"HASPIN"	"hsa:83903; Q5U5K3; Q8TF76; Q96MN1; Q9BXS7"	""	""	"0"	"0"	"8.1"	"2.7"	"8.9"	"5.9"	"5.9"	"8.7"	"4.6"	"6.7"	"8.9"	"25.0"	"38.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8N1G0"	"Zinc finger protein 687 OS=Homo sapiens OX=9606 GN=ZNF687 PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"1237"	"129.4"	"8.19"	""	"3.29"	""	"1"	""	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00096, Pf16622"	"57592"	"ENSG00000143373"	"ZNF687"	"D3DV17; hsa:57592; Q68DQ8; Q8N1G0; Q9H937; Q9P2A7"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82673"	"28S ribosomal protein S35, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS35 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"323"	"36.8"	"8.24"	"335.00"	"3.29"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf10213"	"60488"	"ENSG00000061794"	"MRPS35"	"hsa:60488; P82673; Q32LZ1; Q6P4C6; Q7L1M6; Q8NBP4; Q96AI0; Q9H044; Q9HC14; Q9P1R5"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"14.3"	"9.4"	"14.5"	"10.3"	"10.9"	"12.6"	"16.0"	"16.0"	"18.0"	"27.7"	"49.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4X0"	"AMME syndrome candidate gene 1 protein OS=Homo sapiens OX=9606 GN=AMMECR1 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"333"	"35.4"	"8.63"	"318.08"	"3.29"	"1"	"1"	""	"mitochondrion;nucleus"	""	"Pf01871"	"9949"	"ENSG00000101935"	"AMMECR1"	"hsa:9949; Q5JYV9; Q6P9D8; Q8WX22; Q9UIQ8; Q9Y4X0"	""	""	"0"	"0"	"14.5"	"5.2"	"12.1"	"12.4"	"13.3"	"18.0"	"12.2"	"13.8"	"15.5"	"31.3"	"56.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7RTN6"	"STE20-related kinase adapter protein alpha OS=Homo sapiens OX=9606 GN=STRADA PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"431"	"48.3"	"6.48"	"314.52"	"3.29"	"1"	"1"	"cell cycle OR cell proliferation;transport;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00069"	"92335"	"ENSG00000266173"	"STRADA"	"B4DDE3; B4DW17; hsa:92335; J3KTC9; Q5JPI2; Q7RTN6; Q7Z4K9; Q8NC31; Q8NCF1; Q9H272"	"Energy dependent regulation of mTOR by LKB1-AMPK"	"AMP-activated protein kinase signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HCG8"	"Pre-mRNA-splicing factor CWC22 homolog OS=Homo sapiens OX=9606 GN=CWC22 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"908"	"105.4"	"7.03"	"358.88"	"3.28"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity"	"Pf02847"	"57703"	"ENSG00000163510"	"CWC22"	"hsa:57703; Q05DC2; Q4G135; Q52LF0; Q6PEX2; Q7Z6I0; Q9H5L3; Q9H6Q6; Q9HCG8"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14602"	"Eukaryotic translation initiation factor 1A, Y-chromosomal OS=Homo sapiens OX=9606 GN=EIF1AY PE=1 SV=4"	"0.000"	""	"12"	"2"	"3"	"2"	"144"	"16.4"	"5.24"	"542.35"	"3.28"	"2"	"1"	"protein metabolism;other metabolic processes"	"other cell component"	"nucleic acid binding activity"	"Pf01176"	"9086"	"ENSG00000198692"	"EIF1AY"	"hsa:9086; O14602; Q9BS77"	""	"Translation factors"	"1"	"0"	"490.4"	"204.7"	"372.6"	"382.5"	"401.0"	"525.0"	"441.8"	"633.6"	"455.8"	"815.7"	"950.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P21953"	"2-oxoisovalerate dehydrogenase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=BCKDHB PE=1 SV=2"	"0.001"	""	"3"	"1"	"2"	"1"	"392"	"43.1"	"6.29"	"290.43"	"3.28"	"1"	"1"	"other metabolic processes;other biological processes"	"mitochondrion;nucleus"	"other molecular function"	"Pf02779, Pf02780"	"594"	"ENSG00000083123"	"BCKDHB"	"hsa:594; P21953; Q5T2J3; Q9BQL0"	"Glyoxylate metabolism and glycine degradation; Branched-chain amino acid catabolism"	"Primary ovarian insufficiency"	"3"	"0"	"38.3"	"19.2"	"32.3"	"30.1"	"35.6"	"41.3"	"34.6"	"43.3"	"37.1"	"73.6"	"122.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P04181"	"Ornithine aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OAT PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"439"	"48.5"	"7.03"	"380.00"	"3.27"	"1"	"1"	"other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00202"	"4942"	"ENSG00000065154"	"OAT"	"D3DRF0; hsa:4942; P04181; Q16068; Q16069; Q68CS0; Q6IAV9; Q9UD03"	"Glutamate and glutamine metabolism"	"Amino acid metabolism; 22q11.2 copy number variation syndrome; Creatine pathway"	"4"	"0"	"22.7"	"4.4"	"12.7"	"3.6"	"14.7"	"11.7"	"13.0"	"17.0"	"21.3"	"28.2"	"65.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y5V0"	"Zinc finger protein 706 OS=Homo sapiens OX=9606 GN=ZNF706 PE=1 SV=1"	""	""	"14"	"1"	"1"	"1"	"76"	"8.5"	"10.01"	""	"3.26"	""	"1"	"other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf04419, Pf12874"	"51123"	"ENSG00000120963"	"ZNF706"	"A8K362; hsa:51123; Q9Y5V0"	"Generic Transcription Pathway"	""	"1"	"0"	"138.6"	"93.4"	"124.7"	"109.0"	"120.6"	"144.6"	"126.3"	"153.9"	"193.3"	"478.9"	"526.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKJ3"	"G patch domain-containing protein 8 OS=Homo sapiens OX=9606 GN=GPATCH8 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1502"	"164.1"	"8.66"	"369.70"	"3.26"	"1"	"1"	""	"nucleus"	"other molecular function"	"Pf01585, Pf12171"	"23131"	"ENSG00000186566"	"GPATCH8"	"B9EGP9; hsa:23131; O60300; Q8TB99; Q9UKJ3"	""	""	"0"	"0"	"30.1"	"12.3"	"27.0"	"20.5"	"24.1"	"26.3"	"26.0"	"30.8"	"26.0"	"28.7"	"37.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4B6"	"DDB1- and CUL4-associated factor 1 OS=Homo sapiens OX=9606 GN=DCAF1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1507"	"168.9"	"5.06"	"306.26"	"3.26"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	""	"9730"	"ENSG00000145041"	"DCAF1"	"hsa:9730; Q2YD74; Q8TBD9; Q9HCA1; Q9UG37; Q9Y4B6"	"Antigen processing: Ubiquitination & Proteasome degradation"	"Hippo-Merlin signaling dysregulation"	"2"	"0"	"42.0"	"19.0"	"32.1"	"28.6"	"37.4"	"33.7"	"28.7"	"38.1"	"27.6"	"51.0"	"86.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14757"	"Serine/threonine-protein kinase Chk1 OS=Homo sapiens OX=9606 GN=CHEK1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"476"	"54.4"	"8.25"	"358.72"	"3.24"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1111"	"ENSG00000149554"	"CHEK1"	"A8K934; B4DDD0; B4DSK3; B5BTY6; F5H7S4; H2BI51; hsa:1111; O14757"	"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; TP53 Regulates Transcription of DNA Repair Genes; Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Transcriptional Regulation by E2F6; Signaling by SCF-KIT; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"	"miRNA regulation of DNA damage response; Cell cycle; Retinoblastoma gene in cancer; ATR signaling; ATM signaling in development and disease ; DNA repair pathways, full network; TROP2 regulatory signaling; DNA damage response"	"18"	"0"	"18.8"	"10.8"	"22.2"	"20.5"	"21.6"	"27.3"	"19.2"	"26.2"	"36.3"	"183.5"	"266.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25440"	"Bromodomain-containing protein 2 OS=Homo sapiens OX=9606 GN=BRD2 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"801"	"88.0"	"9.09"	"451.69"	"3.24"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00439, Pf17035"	"6046"	"ENSG00000204256; ENSG00000215077; ENSG00000234507; ENSG00000234704; ENSG00000235307"	"BRD2"	"A2AAU0; B0S7P0; B1AZT1; hsa:6046; O00699; O00700; P25440; Q15310; Q5STC9; Q63HQ9; Q658Y7; Q6P3U2; Q969U4"	"RUNX3 regulates p14-ARF"	""	"1"	"0"	"7.4"	"0.0"	"5.9"	"5.3"	"5.8"	"5.7"	"5.3"	"5.9"	"11.3"	"36.2"	"59.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q93074"	"Mediator of RNA polymerase II transcription subunit 12 OS=Homo sapiens OX=9606 GN=MED12 PE=1 SV=4"	"0.000"	""	"1"	"1"	"2"	"1"	"2177"	"242.9"	"7.05"	"305.33"	"3.24"	"1"	"1"	"cell-cell signaling;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09497, Pf12144, Pf12145"	"9968"	"ENSG00000184634"	"MED12"	"hsa:9968; O15410; O75557; Q93074; Q9UHV6; Q9UND7"	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; Generic Transcription Pathway"	""	"3"	"0"	"10.8"	"5.2"	"8.5"	"9.6"	"13.8"	"10.7"	"10.1"	"14.2"	"7.6"	"30.9"	"72.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75179"	"Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3"	"0.000"	""	"0"	"1"	"2"	"1"	"2603"	"274.1"	"6.52"	"379.99"	"3.23"	"1"	"1"	"stress response;developmental processes;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf00013, Pf12796"	"26057"	"ENSG00000132466"	"ANKRD17"	"E7EUV3; G5E964; hsa:26057; O75179; Q6PJ85; Q6PK85; Q6PKA2; Q86XI3; Q8NDR5; Q96I86; Q9H288; Q9H6J9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96H20"	"Vacuolar-sorting protein SNF8 OS=Homo sapiens OX=9606 GN=SNF8 PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"258"	"28.8"	"6.65"	""	"3.22"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf04157"	"11267"	"ENSG00000159210"	"SNF8"	"hsa:11267; Q8IXY3; Q96H20; Q9UN50"	"HCMV Late Events; Endosomal Sorting Complex Required For Transport (ESCRT)"	""	"2"	"0"	"32.4"	"13.5"	"28.7"	"18.6"	"27.1"	"37.7"	"30.4"	"93.0"	"163.3"	"667.9"	"1324.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BS18"	"Anaphase-promoting complex subunit 13 OS=Homo sapiens OX=9606 GN=ANAPC13 PE=1 SV=1"	"0.000"	""	"18"	"1"	"2"	"1"	"74"	"8.5"	"4.18"	"375.22"	"3.22"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"nucleus"	""	"Pf05839"	"25847"	"ENSG00000129055"	"ANAPC13"	"hsa:25847; Q9BS18; Q9Y3V0"	"Antigen processing: Ubiquitination & Proteasome degradation"	"Cell cycle"	"2"	"0"	"35.3"	"11.7"	"29.6"	"26.4"	"29.5"	"38.9"	"21.8"	"31.5"	"25.7"	"42.9"	"66.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P33316"	"Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=DUT PE=1 SV=4"	"0.000"	""	"5"	"1"	"2"	"1"	"252"	"26.5"	"9.36"	"332.98"	"3.22"	"1"	"1"	"DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;mitochondrion;nucleus"	"signal transduction activity or receptor binding;other molecular function"	"Pf00692"	"1854"	"ENSG00000128951"	"DUT"	"A8K650; B4DPR5; hsa:1854; O14785; P33316; Q16708; Q16860; Q6FHN1; Q6NSA3; Q96Q81"	""	"Pyrimidine metabolism"	"1"	"0"	"12.5"	"3.3"	"8.7"	"4.4"	"6.8"	"14.6"	"11.5"	"13.9"	"15.8"	"23.0"	"61.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H1E3"	"Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 OS=Homo sapiens OX=9606 GN=NUCKS1 PE=1 SV=1"	"0.001"	""	"4"	"1"	"2"	"1"	"243"	"27.3"	"5.08"	"250.14"	"3.21"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	""	"64710"	"ENSG00000069275"	"NUCKS1"	"hsa:64710; Q54AC0; Q5PXE7; Q9H1D6; Q9H1E3; Q9H723"	""	""	"0"	"0"	"101.2"	"52.7"	"81.5"	"94.8"	"119.2"	"169.4"	"195.7"	"312.4"	"195.5"	"200.9"	"347.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P36543"	"V-type proton ATPase subunit E 1 OS=Homo sapiens OX=9606 GN=ATP6V1E1 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"226"	"26.1"	"8.00"	"379.98"	"3.20"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf01991"	"529"	"ENSG00000131100"	"ATP6V1E1"	"A8MUE4; A8MUN4; hsa:529; P36543"	"Amino acids regulate mTORC1; ROS and RNS production in phagocytes; Insulin receptor recycling; Transferrin endocytosis and recycling; Ion channel transport"	"VEGFA-VEGFR2 signaling; Proximal tubule transport"	"7"	"0"	"15.7"	"6.1"	"14.2"	"8.9"	"14.3"	"15.4"	"13.0"	"15.2"	"12.3"	"24.1"	"59.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H444"	"Charged multivesicular body protein 4b OS=Homo sapiens OX=9606 GN=CHMP4B PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"224"	"24.9"	"4.82"	"293.31"	"3.19"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf03357"	"128866"	"ENSG00000101421"	"CHMP4B"	"E1P5N4; hsa:128866; Q53ZD6; Q9H444"	"HCMV Late Events; Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT); Late endosomal microautophagy; Sealing of the nuclear envelope (NE) by ESCRT-III; Macroautophagy; Pyroptosis; Translation of Replicase and Assembly of the Replication Transcription Complex; Translation of Replicase and Assembly of the Replication Transcription Complex"	""	"9"	"0"	"82.9"	"60.4"	"76.4"	"66.7"	"76.4"	"79.3"	"67.6"	"88.2"	"89.0"	"103.8"	"161.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92504"	"Zinc transporter SLC39A7 OS=Homo sapiens OX=9606 GN=SLC39A7 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"469"	"50.1"	"6.87"	"410.33"	"3.19"	"1"	"1"	"transport;other biological processes"	"other membranes;ER/Golgi;nucleus"	"transporter activity"	"Pf02535"	"7922"	"ENSG00000112473; ENSG00000206288; ENSG00000224399; ENSG00000226614; ENSG00000227402; ENSG00000229802"	"SLC39A7"	"B0UXF6; hsa:7922; Q5STP8; Q92504; Q9UIQ0"	"Zinc influx into cells by the SLC39 gene family"	"Nuclear receptors meta-pathway; NRF2 pathway; Zinc homeostasis"	"4"	"0"	"117.9"	"20.3"	"70.1"	"54.6"	"64.5"	"86.2"	"50.7"	"82.8"	"45.9"	"111.8"	"263.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9GZT3"	"SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1"	"0.000"	""	"16"	"2"	"3"	"2"	"109"	"12.3"	"10.24"	"580.98"	"3.19"	"2"	"1"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;mitochondrion;nucleus;other cell component"	""	"Pf00076"	"81892"	"ENSG00000119705"	"SLIRP"	"hsa:81892; J3KMY7; Q9GZT3"	""	""	"0"	"0"	"312.9"	"125.8"	"321.2"	"285.8"	"304.5"	"387.7"	"263.1"	"298.6"	"238.7"	"415.5"	"649.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P12814"	"Alpha-actinin-1 OS=Homo sapiens OX=9606 GN=ACTN1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"892"	"103.0"	"5.41"	"492.61"	"3.19"	"1"	"1"	"cell adhesion;cell organization and biogenesis;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00307, Pf00435, Pf08726"	"87"	"ENSG00000072110"	"ACTN1"	"B3V8S3; B4DHH3; B7TY16; hsa:87; P12814; Q1HE25; Q9BTN1"	"Platelet degranulation ; RHOD GTPase cycle; RHOF GTPase cycle; Nephrin family interactions; Syndecan interactions; RHOBTB2 GTPase cycle; Regulation of cytoskeletal remodeling and cell spreading by IPP complex components"	"Arrhythmogenic right ventricular cardiomyopathy; Focal adhesion; Ebola virus infection in host; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Regulation of actin cytoskeleton"	"12"	"0"	"47.3"	"13.5"	"35.6"	"29.5"	"34.9"	"30.1"	"34.9"	"30.4"	"37.6"	"65.9"	"111.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12789"	"General transcription factor 3C polypeptide 1 OS=Homo sapiens OX=9606 GN=GTF3C1 PE=1 SV=4"	"0.000"	""	"2"	"3"	"4"	"3"	"2109"	"238.7"	"7.30"	"1307.45"	"3.19"	"3"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04182"	"2975"	"ENSG00000077235"	"GTF3C1"	"B2RP21; hsa:2975; Q12789; Q12838; Q6DKN9; Q9Y4W9"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter"	""	"3"	"0"	"53.1"	"19.4"	"42.1"	"27.2"	"37.5"	"54.3"	"31.7"	"43.7"	"44.0"	"75.7"	"125.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HC52"	"Chromobox protein homolog 8 OS=Homo sapiens OX=9606 GN=CBX8 PE=1 SV=3"	"0.000"	""	"4"	"1"	"2"	"1"	"389"	"43.4"	"9.91"	"354.60"	"3.19"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00385, Pf17218"	"57332"	"ENSG00000141570"	"CBX8"	"hsa:57332; Q96H39; Q9HC52; Q9NR07"	"SUMOylation of DNA damage response and repair proteins; Regulation of PTEN gene transcription; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Oxidative Stress Induced Senescence; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"	""	"8"	"0"	"12.7"	"8.6"	"9.6"	"8.6"	"10.1"	"12.1"	"11.6"	"10.5"	"9.2"	"17.8"	"35.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6YN16"	"Hydroxysteroid dehydrogenase-like protein 2 OS=Homo sapiens OX=9606 GN=HSDL2 PE=1 SV=1"	"0.001"	""	"4"	"1"	"2"	"1"	"418"	"45.4"	"7.99"	"262.97"	"3.18"	"1"	"1"	""	"mitochondrion;other cytoplasmic organelle"	"other molecular function"	"Pf00106, Pf02036"	"84263"	"ENSG00000119471"	"HSDL2"	"A8K1L4; A8K8X1; A8MSV3; hsa:84263; Q658M8; Q6YN16; Q9BT58"	""	""	"0"	"0"	"14.4"	"6.7"	"11.3"	"12.6"	"10.5"	"7.7"	"8.3"	"10.6"	"14.9"	"19.1"	"26.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02809"	"Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 OS=Homo sapiens OX=9606 GN=PLOD1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"727"	"83.5"	"6.95"	"384.06"	"3.18"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf03171"	"5351"	"ENSG00000083444"	"PLOD1"	"B4DR87; hsa:5351; Q02809; Q96AV9; Q9H132"	"Collagen biosynthesis and modifying enzymes"	"Type I collagen synthesis in the context of osteogenesis imperfecta"	"2"	"0"	"18.5"	"5.9"	"10.5"	"13.9"	"13.6"	"15.1"	"10.4"	"15.0"	"16.4"	"23.1"	"47.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95983"	"Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1"	"0.000"	""	"10"	"2"	"4"	"2"	"291"	"32.8"	"5.34"	"1070.14"	"3.18"	"2"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01429, Pf14048, Pf16564"	"53615"	"ENSG00000071655"	"MBD3"	"A8K4B7; D6W5Z2; hsa:53615; O95983; Q6PIL9; Q6PJZ9; Q86XF4"	"Potential therapeutics for SARS; HDACs deacetylate histones; Regulation of PTEN gene transcription; RNA Polymerase I Transcription Initiation; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of TP53 Activity through Acetylation"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"7"	"0"	"107.2"	"47.4"	"115.6"	"93.2"	"107.0"	"120.0"	"106.5"	"129.9"	"99.5"	"168.8"	"236.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5JSH3"	"WD repeat-containing protein 44 OS=Homo sapiens OX=9606 GN=WDR44 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"913"	"101.3"	"5.45"	"302.89"	"3.17"	"1"	"1"	""	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf00400"	"54521"	"ENSG00000131725"	"WDR44"	"B4DSE9; F8W913; hsa:54521; Q0JS52; Q0JTF3; Q5JSH2; Q5JSH3; Q6ZSC1; Q7Z365; Q7Z3P6; Q8NAU8; Q8NHU5; Q9NUV4"	""	"Ectoderm differentiation"	"1"	"0"	"5.8"	"2.7"	"5.1"	"4.9"	"4.9"	"11.7"	"20.0"	"34.4"	"41.8"	"65.5"	"76.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y3B9"	"RRP15-like protein OS=Homo sapiens OX=9606 GN=RRP15 PE=1 SV=2"	""	""	"7"	"1"	"1"	"1"	"282"	"31.5"	"5.52"	""	"3.17"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"other cell component"	""	"Pf07890"	"51018"	"ENSG00000067533"	"RRP15"	"hsa:51018; Q9Y3B9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q00341"	"Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1268"	"141.4"	"6.87"	"332.21"	"3.15"	"1"	"1"	"other metabolic processes;transport"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013"	"3069"	"ENSG00000115677"	"HDLBP"	"B4DTQ2; E7EM71; hsa:3069; Q00341; Q53QU2; Q9UCY3"	"HDL clearance"	"2q37 copy number variation syndrome"	"2"	"0"	"43.6"	"13.0"	"47.3"	"32.4"	"37.8"	"43.9"	"38.1"	"47.4"	"37.3"	"68.3"	"114.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UJZ1"	"Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"356"	"38.5"	"7.39"	"363.73"	"3.15"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;mitochondrion"	"signal transduction activity or receptor binding;other molecular function"	"Pf01145, Pf16200"	"30968"	"ENSG00000165283"	"STOML2"	"B4E1K7; D3DRN3; hsa:30968; O60376; Q53G29; Q96FY2; Q9P042; Q9UJZ1"	"Processing of SMDT1"	""	"1"	"0"	"12.2"	"5.3"	"14.2"	"11.0"	"14.6"	"14.1"	"12.0"	"13.9"	"10.6"	"32.2"	"66.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86UY8"	"5'-nucleotidase domain-containing protein 3 OS=Homo sapiens OX=9606 GN=NT5DC3 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"548"	"63.4"	"8.31"	"341.19"	"3.14"	"1"	"1"	""	"cytosol;other cell component"	"other molecular function"	"Pf05761"	"51559"	"ENSG00000111696"	"NT5DC3"	"hsa:51559; Q86UY8; Q9NUM7; Q9P2T2; Q9P2T3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z417"	"Nuclear fragile X mental retardation-interacting protein 2 OS=Homo sapiens OX=9606 GN=NUFIP2 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"695"	"76.1"	"8.70"	"396.38"	"3.14"	"1"	"1"	""	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity"	"Pf15293"	"57532"	"ENSG00000108256"	"NUFIP2"	"A1L3A6; A1L3A7; hsa:57532; Q7Z417; Q9P2M5"	""	""	"0"	"0"	"163.3"	"55.9"	"174.9"	"159.9"	"163.2"	"188.5"	"122.7"	"180.6"	"92.1"	"272.7"	"582.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5B6"	"PAX3- and PAX7-binding protein 1 OS=Homo sapiens OX=9606 GN=PAXBP1 PE=1 SV=2"	"0.000"	""	"2"	"2"	"3"	"2"	"917"	"104.7"	"5.68"	"554.99"	"3.14"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf07842"	"94104"	"ENSG00000159086; ENSG00000263141"	"PAXBP1"	"D3DSE7; hsa:94104; Q96DU8; Q9NYQ0; Q9Y5B6"	""	""	"0"	"0"	"267.9"	"80.9"	"162.3"	"123.0"	"154.1"	"173.9"	"126.2"	"169.5"	"141.4"	"231.0"	"445.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NWH9"	"SAFB-like transcription modulator OS=Homo sapiens OX=9606 GN=SLTM PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1034"	"117.1"	"7.87"	"377.98"	"3.14"	"1"	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf02037"	"79811"	"ENSG00000137776"	"SLTM"	"A8K5V8; B2RTX3; hsa:79811; Q2VPK7; Q52MB3; Q658J7; Q6ZNF2; Q86TK6; Q9H7C3; Q9H8U9; Q9NWH9"	""	""	"0"	"0"	"350.4"	"93.8"	"198.7"	"132.9"	"183.4"	"180.2"	"149.6"	"206.8"	"160.0"	"285.2"	"525.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A5PLN9"	"Trafficking protein particle complex subunit 13 OS=Homo sapiens OX=9606 GN=TRAPPC13 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"417"	"46.5"	"5.60"	"338.80"	"3.14"	"1"	"1"	"cell organization and biogenesis;transport"	"cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf06159"	"80006"	"ENSG00000113597"	"TRAPPC13"	"A5PLN9; hsa:80006; Q17RZ9; Q49A23; Q4JHG0; Q6MZG4; Q8TCM2; Q9H8I3"	"RAB GEFs exchange GTP for GDP on RABs"	""	"1"	"0"	"9.6"	"2.8"	"7.4"	"6.3"	"5.9"	"5.0"	"6.8"	"9.5"	"7.7"	"19.3"	"72.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NP81"	"Serine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=SARS2 PE=1 SV=1"	"0.001"	""	"2"	"1"	"2"	"1"	"518"	"58.2"	"8.13"	"267.77"	"3.14"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00587"	"54938"	"ENSG00000104835; ENSG00000283104"	"SARS2"	"A6NHW7; B4DE10; hsa:54938; Q9BVP3; Q9NP81"	"Mitochondrial tRNA aminoacylation"	""	"1"	"0"	"23.3"	"7.3"	"19.7"	"20.5"	"23.0"	"20.3"	"19.9"	"22.5"	"26.5"	"46.8"	"118.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q4VC05"	"B-cell CLL/lymphoma 7 protein family member A OS=Homo sapiens OX=9606 GN=BCL7A PE=1 SV=1"	"0.000"	""	"10"	"2"	"3"	"2"	"210"	"22.8"	"5.14"	"818.37"	"3.13"	"2"	"1"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	""	"Pf04714"	"605"	"ENSG00000110987; ENSG00000282873"	"BCL7A"	"B4DJN6; B7ZB21; hsa:605; Q13843; Q14CT7; Q4VC05"	""	""	"0"	"0"	"254.1"	"99.3"	"219.5"	"246.1"	"257.3"	"302.7"	"275.7"	"402.7"	"236.2"	"300.9"	"452.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q06124"	"Tyrosine-protein phosphatase non-receptor type 11 OS=Homo sapiens OX=9606 GN=PTPN11 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"593"	"68.0"	"7.30"	"428.22"	"3.11"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00017, Pf00102"	"5781"	"ENSG00000179295"	"PTPN11"	"A8K1D9; hsa:5781; Q06124; Q96HD7"	"PIP3 activates AKT signaling; GPVI-mediated activation cascade; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Platelet sensitization by LDL; CTLA4 inhibitory signaling; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Interleukin-3, Interleukin-5 and GM-CSF signaling; PD-1 signaling; Activation of IRF3, IRF7 mediated by TBK1, IKBKE; Signal regulatory protein family interactions; Constitutive Signaling by Aberrant PI3K in Cancer; RET signaling; PI3K Cascade; Signaling by SCF-KIT; Downstream signal transduction; Tie2 Signaling; Interleukin-6 signaling; Signaling by Leptin; Regulation of IFNG signaling; Regulation of IFNA/IFNB signaling; Signaling by CSF3 (G-CSF); GAB1 signalosome; Signaling by CSF1 (M-CSF) in myeloid cells; PI-3K cascade:FGFR1; FRS-mediated FGFR1 signaling; PI-3K cascade:FGFR2; FRS-mediated FGFR2 signaling; FRS-mediated FGFR3 signaling; PI-3K cascade:FGFR3; FRS-mediated FGFR4 signaling; PI-3K cascade:FGFR4; Activated NTRK2 signals through FRS2 and FRS3; Spry regulation of FGF signaling; MAPK3 (ERK1) activation; MAPK1 (ERK2) activation; Prolactin receptor signaling; Interleukin-20 family signaling; Netrin mediated repulsion signals; Interleukin-37 signaling; PECAM1 interactions; MET activates PTPN11; STAT5 activation downstream of FLT3 ITD mutants; Regulation of RUNX1 Expression and Activity; STAT5 Activation"	"IL-5 signaling pathway; Heart development; IL-1 signaling pathway; Leptin signaling pathway; Prolactin signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; Pilocytic astrocytoma; Androgen receptor network in prostate cancer; B cell receptor signaling pathway; Interleukin-11 signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Alpha 6 beta 4 signaling pathway; IL-3 signaling pathway; Kit receptor signaling pathway; Hepatocyte growth factor receptor signaling; RAC1/PAK1/p38/MMP2 pathway; IL6 signaling pathway; Hepatitis C and hepatocellular carcinoma; VEGFA-VEGFR2 signaling; Embryonic stem cell pluripotency pathways; IL-4 signaling pathway; Ras signaling; EGF/EGFR signaling pathway; Fragile X syndrome; Cancer immunotherapy by CTLA4 blockade; Cancer immunotherapy by PD-1 blockade; Gastrin signaling pathway; Netrin-UNC5B signaling pathway; Insulin signaling; IL-2 signaling pathway; Angiotensin II receptor type 1 pathway; Kallmann syndrome; Orexin receptor pathway; GDNF signaling; Interferon type I signaling pathways; Type II interferon signaling; T-cell receptor signaling pathway"	"90"	"0"	"8.0"	"4.8"	"8.5"	"6.3"	"7.9"	"9.8"	"5.6"	"11.3"	"8.3"	"18.1"	"34.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6DCA0"	"AMMECR1-like protein OS=Homo sapiens OX=9606 GN=AMMECR1L PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"310"	"34.5"	"8.98"	"346.70"	"3.11"	"1"	"1"	""	""	""	"Pf01871"	"83607"	"ENSG00000144233"	"AMMECR1L"	"B4E276; hsa:83607; Q6DCA0"	""	""	"0"	"0"	"8.7"	"0.0"	"6.0"	"6.5"	"8.3"	"10.5"	"9.4"	"12.1"	"12.5"	"38.1"	"68.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NQP4"	"Prefoldin subunit 4 OS=Homo sapiens OX=9606 GN=PFDN4 PE=1 SV=1"	"0.001"	""	"11"	"1"	"2"	"1"	"134"	"15.3"	"4.53"	"277.33"	"3.11"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01920"	"5203"	"ENSG00000101132"	"PFDN4"	"hsa:5203; Q5TD11; Q92779; Q9NQP4"	"Prefoldin mediated transfer of substrate  to CCT/TriC"	"Cellular proteostasis"	"2"	"0"	"106.3"	"58.8"	"89.7"	"94.6"	"93.4"	"110.2"	"91.0"	"121.1"	"87.9"	"151.2"	"224.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BRJ7"	"Tudor-interacting repair regulator protein OS=Homo sapiens OX=9606 GN=NUDT16L1 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"211"	"23.3"	"8.91"	"342.56"	"3.10"	"1"	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity"	""	"84309"	"ENSG00000168101"	"NUDT16L1"	"hsa:84309; Q8NAI2; Q9BRJ7"	""	""	"0"	"0"	"16.0"	"4.8"	"13.0"	"9.5"	"14.1"	"20.5"	"11.7"	"18.9"	"13.9"	"17.7"	"31.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UQR0"	"Sex comb on midleg-like protein 2 OS=Homo sapiens OX=9606 GN=SCML2 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"700"	"77.2"	"8.54"	"340.63"	"3.10"	"1"	"1"	"other biological processes"	"nucleus"	""	"Pf00536, Pf02820, Pf12140, Pf17208"	"10389"	"ENSG00000102098"	"SCML2"	"hsa:10389; Q5JXE6; Q86U98; Q8IWD0; Q8NDP2; Q9UGC5; Q9UQR0"	""	""	"0"	"0"	"24.2"	"11.2"	"18.4"	"14.5"	"17.5"	"21.3"	"16.6"	"26.8"	"28.8"	"36.3"	"85.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VT52"	"Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1461"	"155.9"	"7.42"	"279.49"	"3.10"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf04818"	"23248"	"ENSG00000163125"	"RPRD2"	"A8K6N8; B3KPT1; B4E2Q6; hsa:23248; O75048; Q5VT51; Q5VT52; Q5VT53; Q6MZL4; Q86XD2; Q9P0D7"	"RNA polymerase II transcribes snRNA genes"	""	"1"	"0"	"28.5"	"8.9"	"12.0"	"10.0"	"15.1"	"16.5"	"18.2"	"22.3"	"14.3"	"29.8"	"37.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96FV9"	"THO complex subunit 1 OS=Homo sapiens OX=9606 GN=THOC1 PE=1 SV=1"	"0.000"	""	"4"	"2"	"3"	"2"	"657"	"75.6"	"4.98"	"773.19"	"3.08"	"2"	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;transport;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00531, Pf11957"	"9984"	"ENSG00000079134"	"THOC1"	"B2RBP6; hsa:9984; Q15219; Q64I72; Q64I73; Q96FV9"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	""	"3"	"0"	"55.3"	"21.4"	"48.5"	"40.1"	"45.9"	"45.6"	"38.8"	"46.1"	"38.0"	"78.4"	"174.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00308"	"NEDD4-like E3 ubiquitin-protein ligase WWP2 OS=Homo sapiens OX=9606 GN=WWP2 PE=1 SV=2"	"0.001"	""	"1"	"1"	"2"	"1"	"870"	"98.9"	"7.12"	"271.51"	"3.08"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00397, Pf00632"	"11060"	"ENSG00000198373"	"WWP2"	"A6NEP1; B2R706; B4DTL5; F5H213; H3BRF3; hsa:11060; I3RSG8; O00308; Q6ZTQ5; Q96CZ2; Q9BWN6"	"RHOQ GTPase cycle; Regulation of PTEN stability and activity; RHOJ GTPase cycle; NOTCH3 Activation and Transmission of Signal to the Nucleus; RHOU GTPase cycle"	""	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UNZ2"	"NSFL1 cofactor p47 OS=Homo sapiens OX=9606 GN=NSFL1C PE=1 SV=2"	""	""	"5"	"1"	"1"	"1"	"370"	"40.5"	"5.10"	""	"3.08"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00789, Pf08059, Pf14555"	"55968"	"ENSG00000088833"	"NSFL1C"	"A2A2L1; B2RD74; hsa:55968; Q5JXA4; Q5JXA5; Q7Z533; Q9H102; Q9NVL9; Q9UI06; Q9UNZ2"	"RHOH GTPase cycle"	"Alstrom syndrome"	"2"	"0"	"30.3"	"25.4"	"40.0"	"32.4"	"40.2"	"40.2"	"34.8"	"29.2"	"23.4"	"33.8"	"51.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8WWI1"	"LIM domain only protein 7 OS=Homo sapiens OX=9606 GN=LMO7 PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"1683"	"192.6"	"8.09"	""	"3.08"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00307, Pf00412, Pf00595, Pf15949"	"4008"	"ENSG00000136153"	"LMO7"	"E9PLH4; hsa:4008; O15462; O95346; Q5TBK6; Q8WWI1; Q9UKC1; Q9UQM5; Q9Y6A7"	"Antigen processing: Ubiquitination & Proteasome degradation; Neddylation; Signaling by ALK fusions and activated point mutants"	""	"3"	"0"	"11.3"	"3.5"	"11.0"	"8.3"	"7.8"	"6.7"	"10.3"	"10.5"	"12.8"	"29.0"	"55.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14571"	"Inositol 1,4,5-trisphosphate receptor type 2 OS=Homo sapiens OX=9606 GN=ITPR2 PE=1 SV=2"	"0.000"	""	"1"	"3"	"4"	"2"	"2701"	"307.9"	"6.43"	"846.69"	"3.07"	"3"	"1"	"stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00520, Pf01365, Pf02815, Pf08454, Pf08709"	"3709"	"ENSG00000123104"	"ITPR2"	"hsa:3709; O94773; Q14571"	"Role of phospholipids in phagocytosis; FCERI mediated Ca+2 mobilization; FCGR3A-mediated IL10 synthesis; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Ion homeostasis; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Ca2+ pathway; VEGFR2 mediated cell proliferation; Elevation of cytosolic Ca2+ levels; PLC beta mediated events; DAG and IP3 signaling; CLEC7A (Dectin-1) induces NFAT activation; Effects of PIP2 hydrolysis"	"Alzheimer's disease and miRNA effects; Myometrial relaxation and contraction pathways; Vitamin D-sensitive calcium signaling in depression; Thyroid hormones production and peripheral downstream signaling effects; Alzheimer's disease; GDNF signaling; Calcium regulation in cardiac cells"	"21"	"0"	"519.0"	"179.6"	"367.1"	"371.6"	"355.8"	"437.8"	"333.3"	"516.6"	"376.1"	"644.0"	"912.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BWF3"	"RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"364"	"40.3"	"7.08"	"333.55"	"3.06"	"1"	"1"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00098"	"5936"	"ENSG00000173933"	"RBM4"	"B3KUN0; B4E1U0; E7EQS3; hsa:5936; O02916; Q4VC48; Q6P1P2; Q8WU85; Q9BWF3"	"Circadian Clock"	""	"1"	"0"	"221.5"	"80.9"	"208.1"	"148.1"	"176.5"	"217.3"	"151.4"	"198.4"	"156.6"	"286.1"	"470.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IYB5"	"Stromal membrane-associated protein 1 OS=Homo sapiens OX=9606 GN=SMAP1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"467"	"50.4"	"8.75"	"319.34"	"3.06"	"1"	"1"	"other biological processes"	"plasma membrane;other membranes;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01412"	"60682"	"ENSG00000112305"	"SMAP1"	"hsa:60682; Q53H70; Q5SYQ2; Q6PK24; Q8IYB5; Q8NDH4; Q96L38; Q96L39; Q9H8X4"	""	""	"0"	"0"	"19.5"	"10.2"	"22.7"	"19.4"	"20.8"	"24.3"	"17.0"	"26.0"	"23.0"	"32.9"	"41.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96C57"	"Protein CUSTOS OS=Homo sapiens OX=9606 GN=CUSTOS PE=1 SV=2"	"0.001"	""	"4"	"1"	"2"	"1"	"262"	"28.2"	"9.42"	"249.39"	"3.06"	"1"	"1"	"cell-cell signaling;signal transduction;other biological processes"	"nucleus"	""	""	"64897"	"ENSG00000157895"	"CUSTOS"	"hsa:64897; Q53HF0; Q96C57; Q9H9Z7"	""	""	"0"	"0"	"51.7"	"27.4"	"57.5"	"50.6"	"53.8"	"61.5"	"65.2"	"82.9"	"78.4"	"193.2"	"364.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95793"	"Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"577"	"63.1"	"9.44"	"357.58"	"3.06"	"1"	"1"	"cell organization and biogenesis;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00035, Pf16482"	"6780"	"ENSG00000124214"	"STAU1"	"A8K9Z4; E1P5Y1; E1P608; hsa:6780; O95793; Q5JW29; Q6GTM4; Q9H5B4; Q9H5B5; Q9Y3Q2"	""	""	"0"	"0"	"22.0"	"8.2"	"15.8"	"20.7"	"19.4"	"20.3"	"16.0"	"19.3"	"17.8"	"43.3"	"60.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75367"	"Core histone macro-H2A.1 OS=Homo sapiens OX=9606 GN=MACROH2A1 PE=1 SV=4"	"0.000"	""	"3"	"1"	"2"	"1"	"372"	"39.6"	"9.79"	"367.46"	"3.06"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00125, Pf01661, Pf16211"	"100394084; 100998964; 101131222; 101381952; 101564704; 101706296; 102008188; 102123677; 103079324; 104855290; 105467125; 105506940; 105531308; 105816031; 105869993; 108529540; 462076; 481514; 711836"	"ENSAMEG00000017887; ENSBMSG00010001156; ENSCAFG00000001076; ENSCAFG00020007175; ENSCAFG00030007355; ENSCAFG00040009734; ENSCANG00000022762; ENSCJAG00000005818; ENSCLAG00000016530; ENSCWAG00000001657; ENSFCAG00000013924; ENSGGOG00000001707; ENSLCNG00005003680; ENSMICG00000005677; ENSMLEG00000037795; ENSMMNG00015002866; ENSMNEG00000031666; ENSMPUG00000010011; ENSPANG00000002758; ENSPCOG00000013464; ENSPCTG00005011747; ENSPLOG00000000479; ENSPPAG00000029258; ENSPPYG00000015799; ENSPSMG00000021213; ENSPSNG00000019193; ENSPTRG00000017256; ENSRBIG00000034425; ENSRROG00000045755; ENSSBOG00000034640; ENSSSUG00005001976; ENSSVLG00005008251; ENSTGEG00000021330; ENSVVUG00000017487"	"H2afy; H2AFY; LOC100466888; LOC101338325; LOC101381952; LOC101564704; LOC102987354; LOC103079324; LOC103663804; LOC105869993; LOC106989149; LOC110591142; LOC111141291; LOC111182462; LOC112404331; LOC112625777; LOC112815157; LOC112861289; LOC112917035; LOC113928700; LOC114891795; LOC115516119; LOC116529369; LOC116750637; MACROH2A1"	"A0A091CNU6; A0A096N0E8; A0A2J8LRK8; A0A2J8VQ67; A0A2K5HRC8; A0A2K5W7N1; A0A2K5ZHE4; A0A2K6BUT6; A0A2K6EU20; A0A2K6LBL0; A0A2K6RXM8; A0A2K6UYW1; A0A2R9A926; A0A2U3WAW1; A0A2Y9IU30; A0A2Y9PFA0; A0A2Y9SS16; A0A340XJ26; A0A341BZA5; A0A3Q7NDG6; A0A3Q7S763; A0A484GVZ9; A0A485NYK5; A0A5S6R987; A0A667GC30; A0A673T0D7; A0A6G1ASZ6; A0A6J2AVA7; A0A6J2DX40; A0A6J3FC37; A0A6J3R528; A0A6P3F5E4; A0A6P6HX24; A0A8B7G616; A0A8C0C880; A0A8C0K484; A0A8C0S4U0; A0A8C2W4Z6; A0A8C3VQP8; A0A8C6F240; A0A8C8WAC0; A0A8C9AAB1; A0A8C9CK62; A0A8D2BC14; A0A8D2FWT2; A0A8I5UBU0; A0A8J8XTA7; A0A8M1F844; A0A8M1MQV0; A0A8P0N4A7; aju:106989149; cang:105506940; D2GVK3; dle:111182462; elk:111141291; F7HN69; G3QH59; G5BQ26; G7MUD7; ggo:101131222; H2QRI8; I2CUE9; lve:103079324; M3WJR3; M3YF29; mcf:102123677; mleu:105531308; mmur:105869993; mni:105467125; mpuf:101692673; nsu:110591142; oro:101381952; panu:100998964; pcad:102987354; pcoq:105816031; ptr:462076; rbb:108529540; sbq:101050376; umr:103663804; vvp:112917035; zca:113928700"	""	""	"0"	"0"	"94.6"	"43.0"	"83.3"	"58.8"	"76.1"	"84.8"	"76.1"	"90.8"	"86.7"	"169.5"	"229.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08243"	"Asparagine synthetase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=ASNS PE=1 SV=4"	"0.000"	""	"3"	"2"	"3"	"2"	"561"	"64.3"	"6.86"	"561.81"	"3.05"	"2"	"1"	"other metabolic processes;stress response;other biological processes"	"cytosol"	"other molecular function"	"Pf00733, Pf13537"	"440"	"ENSG00000070669"	"ASNS"	"A4D1I8; B4DXZ1; B7ZAA9; D6W5R3; E9PCI3; E9PCX6; hsa:440; P08184; P08243; Q15666; Q549T9; Q96HD0"	"Aspartate and asparagine metabolism; Response of EIF2AK1 (HRI) to heme deficiency; ATF4 activates genes in response to endoplasmic reticulum  stress; Response of EIF2AK4 (GCN2) to amino acid deficiency"	"Photodynamic therapy-induced unfolded protein response; Amino acid metabolism"	"6"	"0"	"316.3"	"114.9"	"202.4"	"144.1"	"221.1"	"213.7"	"178.6"	"212.7"	"243.1"	"345.9"	"581.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95379"	"Tumor necrosis factor alpha-induced protein 8 OS=Homo sapiens OX=9606 GN=TNFAIP8 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"198"	"23.0"	"7.93"	"370.04"	"3.05"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"enzyme regulator activity"	"Pf05527"	"25816"	"ENSG00000145779"	"TNFAIP8"	"B3KMH1; B3KMI2; B7Z713; hsa:25816; O95379; Q9P1Q1; Q9UER5; Q9UP47"	"PI Metabolism"	""	"1"	"0"	"38.3"	"10.9"	"36.4"	"44.6"	"51.1"	"63.2"	"76.9"	"157.1"	"152.2"	"318.2"	"345.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P1K2"	"Polyamine-modulated factor 1 OS=Homo sapiens OX=9606 GN=PMF1 PE=1 SV=2"	"0.000"	""	"6"	"1"	"2"	"1"	"205"	"23.3"	"5.49"	"306.78"	"3.05"	"1"	"1"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf03980"	"100527963; 11243"	"ENSG00000160783"	"PMF1"	"A8K0C5; hsa:100527963; hsa:11243; Q5TCJ8; Q5TCJ9; Q5TCK0; Q5TCK1; Q5TCK3; Q69YZ9; Q6P1K2; Q6PHR4; Q6ZVE6; Q86VJ6; Q8N4T6; Q9UBQ3"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	""	"6"	"0"	"13.8"	"3.5"	"10.0"	"8.6"	"6.5"	"11.2"	"7.1"	"13.0"	"18.9"	"36.6"	"66.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BYI3"	"Hyccin OS=Homo sapiens OX=9606 GN=FAM126A PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"521"	"57.6"	"8.16"	"293.85"	"3.05"	"1"	"1"	"other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf09790"	"84668"	"ENSG00000122591"	"HYCC1"	"A0A024RA06; A4D145; B8ZZJ1; hsa:84668; Q6N010; Q75MR4; Q7LDZ4; Q96MX1; Q96NQ6; Q9BYI3"	""	""	"0"	"0"	"29.3"	"17.1"	"27.7"	"22.8"	"29.6"	"33.0"	"28.2"	"36.7"	"46.4"	"168.6"	"289.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96QE3"	"ATPase family AAA domain-containing protein 5 OS=Homo sapiens OX=9606 GN=ATAD5 PE=1 SV=4"	"0.001"	""	"1"	"1"	"2"	"1"	"1844"	"207.4"	"9.19"	"271.89"	"3.04"	"1"	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00004"	"79915"	"ENSG00000176208"	"ATAD5"	"hsa:79915; Q05DH0; Q69YR6; Q96QE3; Q9H9I1"	""	""	"0"	"0"	"21.8"	"3.6"	"26.2"	"22.6"	"26.6"	"29.0"	"15.5"	"25.8"	"14.6"	"63.2"	"109.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UHN6"	"Cell surface hyaluronidase OS=Homo sapiens OX=9606 GN=CEMIP2 PE=1 SV=1"	"0.001"	""	"1"	"1"	"2"	"1"	"1383"	"154.3"	"8.15"	"265.58"	"3.04"	"1"	"1"	"other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf10162, Pf15711"	"23670"	"ENSG00000135048"	"CEMIP2"	"A6H8W9; B2RTQ6; hsa:23670; Q5T838; Q5T839; Q5T840; Q5T841; Q8NBP6; Q9P2D5; Q9UHN6"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62310"	"U6 snRNA-associated Sm-like protein LSm3 OS=Homo sapiens OX=9606 GN=LSM3 PE=1 SV=2"	"0.001"	""	"9"	"1"	"2"	"1"	"102"	"11.8"	"4.70"	"273.18"	"3.04"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	"27258"	"ENSG00000170860"	"LSM3"	"hsa:27258; P62310; Q6IAH0; Q9Y4Z1"	"mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9BVS5"	"tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=TRMT61B PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"477"	"52.9"	"6.62"	""	"3.03"	""	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf08704"	"55006"	"ENSG00000171103"	"TRMT61B"	"hsa:55006; Q9BVS5; Q9H0Q9; Q9NWS7"	"tRNA modification in the mitochondrion"	""	"1"	"0"	"8.3"	"3.6"	"8.3"	"10.3"	"9.5"	"8.3"	"7.5"	"6.5"	"4.6"	"11.8"	"57.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09669"	"Cytochrome c oxidase subunit 6C OS=Homo sapiens OX=9606 GN=COX6C PE=1 SV=2"	"0.000"	""	"11"	"1"	"2"	"1"	"75"	"8.8"	"10.39"	"337.94"	"3.03"	"1"	"1"	"other metabolic processes"	"other membranes;mitochondrion"	""	"Pf02937"	"1345"	"ENSG00000164919"	"COX6C"	"B2R4D7; hsa:1345; P09669"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"Electron transport chain: OXPHOS system in mitochondria; Ciliary landscape; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly; 5q35 copy number variation"	"8"	"0"	"205.2"	"53.9"	"98.8"	"57.3"	"103.7"	"87.3"	"103.0"	"140.0"	"139.0"	"239.3"	"400.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N1B4"	"Vacuolar protein sorting-associated protein 52 homolog OS=Homo sapiens OX=9606 GN=VPS52 PE=1 SV=1"	"0.001"	""	"2"	"1"	"2"	"1"	"723"	"82.2"	"5.99"	"282.96"	"3.03"	"1"	"1"	"transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf04129"	"6293"	"ENSG00000206286; ENSG00000223501; ENSG00000224455; ENSG00000225590; ENSG00000228425; ENSG00000236014"	"VPS52"	"A2BF38; B0UZZ4; B4DNI9; hsa:6293; Q53GR4; Q5JPA0; Q5SQW1; Q8IUN6; Q8N1B4; Q9NPT5"	"Retrograde transport at the Trans-Golgi-Network"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92506"	"Estradiol 17-beta-dehydrogenase 8 OS=Homo sapiens OX=9606 GN=HSD17B8 PE=1 SV=2"	"0.000"	""	"5"	"1"	"2"	"1"	"261"	"27.0"	"6.54"	"321.29"	"3.02"	"1"	"1"	"cell organization and biogenesis;other metabolic processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf13561"	"7923"	"ENSG00000112474; ENSG00000204228; ENSG00000225312; ENSG00000228357; ENSG00000228712; ENSG00000232357"	"HSD17B8"	"A6NLX7; hsa:7923; Q5STP7; Q92506; Q9UIQ1"	"Fatty acyl-CoA biosynthesis"	""	"1"	"0"	"25.3"	"12.5"	"31.2"	"19.1"	"23.9"	"30.6"	"23.2"	"28.9"	"25.9"	"52.2"	"61.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75534"	"Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2"	"0.000"	""	"2"	"2"	"3"	"2"	"798"	"88.8"	"6.25"	"604.16"	"3.01"	"2"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"nucleic acid binding activity"	"Pf00313, Pf12901"	"7812"	"ENSG00000009307"	"CSDE1"	"A8K281; E9PGZ0; G5E9Q2; hsa:7812; O75534; O94961; Q5TF04; Q5TF05; Q68DF1; Q68DI9; Q9Y2S4"	""	""	"0"	"0"	"227.1"	"73.9"	"143.6"	"115.9"	"162.3"	"159.5"	"122.5"	"157.3"	"163.8"	"297.5"	"542.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UG63"	"ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"623"	"71.2"	"7.37"	"347.24"	"3.01"	"1"	"1"	""	""	"other molecular function"	"Pf00005, Pf12848"	"10061; 114483834"	"ENSG00000033050"	"ABCF2"	"hsa:10061; hsa:114483834; O60864; Q75MJ0; Q75MJ1; Q96TE8; Q9UG63"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5A9"	"YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2"	"0.000"	""	"4"	"3"	"5"	"2"	"579"	"62.3"	"8.79"	"977.91"	"3.00"	"3"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity"	"Pf04146"	"51441"	"ENSG00000198492"	"YTHDF2"	"A6NKG4; A8K966; B4E1G7; D3DPM8; hsa:51441; Q5VSZ9; Q8TDH0; Q9BUJ5; Q9Y5A9"	""	""	"0"	"0"	"359.0"	"169.5"	"342.1"	"319.2"	"287.3"	"395.3"	"286.7"	"379.9"	"285.0"	"593.8"	"757.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H4B0"	"Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OSGEPL1 PE=2 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"414"	"45.1"	"8.56"	"405.96"	"2.99"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00814"	"64172"	"ENSG00000128694"	"OSGEPL1"	"hsa:64172; Q96EV9; Q96NH5; Q9H4B0"	""	""	"0"	"0"	"5.3"	"2.7"	"6.2"	"3.7"	"11.1"	"8.5"	"3.7"	"9.8"	"16.9"	"68.6"	"176.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y2Q5"	"Ragulator complex protein LAMTOR2 OS=Homo sapiens OX=9606 GN=LAMTOR2 PE=1 SV=1"	""	""	"14"	"1"	"1"	"1"	"125"	"13.5"	"5.40"	""	"2.99"	""	"1"	"signal transduction;other biological processes"	"plasma membrane;other membranes;other cytoplasmic organelle"	"enzyme regulator activity;other molecular function"	"Pf03259"	"28956"	"ENSG00000116586"	"LAMTOR2"	"hsa:28956; Q5VY97; Q5VY98; Q5VY99; Q9Y2Q5"	"Neutrophil degranulation; MAP2K and MAPK activation; Regulation of PTEN gene transcription; Macroautophagy; Amino acids regulate mTORC1; mTORC1-mediated signalling; TP53 Regulates Metabolic Genes; Energy dependent regulation of mTOR by LKB1-AMPK"	""	"9"	"0"	"25.2"	"11.2"	"19.6"	"18.5"	"21.3"	"20.1"	"17.0"	"18.1"	"19.5"	"36.7"	"53.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q969X6"	"U3 small nucleolar RNA-associated protein 4 homolog OS=Homo sapiens OX=9606 GN=UTP4 PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"686"	"76.8"	"8.85"	""	"2.99"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00400"	"84916"	"ENSG00000141076; ENSG00000262788"	"UTP4"	"hsa:84916; Q8NCD9; Q8TF14; Q969X6; Q96SP0; Q96SR9; Q96SZ9; Q96T13; Q9BWK6"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	"9.6"	"4.8"	"13.9"	"10.2"	"8.9"	"16.0"	"11.6"	"16.9"	"9.1"	"48.7"	"167.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14573"	"Inositol 1,4,5-trisphosphate receptor type 3 OS=Homo sapiens OX=9606 GN=ITPR3 PE=1 SV=2"	"0.000"	""	"1"	"2"	"3"	"1"	"2671"	"303.9"	"6.48"	"574.70"	"2.99"	"2"	"1"	"transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00520, Pf01365, Pf02815, Pf08454, Pf08709"	"3710"	"ENSG00000096433"	"ITPR3"	"hsa:3710; Q14573; Q14649; Q5TAQ2"	"Ion homeostasis; Effects of PIP2 hydrolysis; Role of phospholipids in phagocytosis; FCERI mediated Ca+2 mobilization; FCGR3A-mediated IL10 synthesis; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Sensory perception of sweet, bitter, and umami (glutamate) taste; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Ca2+ pathway; VEGFR2 mediated cell proliferation; Elevation of cytosolic Ca2+ levels; PLC beta mediated events; DAG and IP3 signaling; CLEC7A (Dectin-1) induces NFAT activation"	"Alzheimer's disease and miRNA effects; Myometrial relaxation and contraction pathways; MFAP5-mediated ovarian cancer cell motility and invasiveness; GPR40 pathway; Vitamin D-sensitive calcium signaling in depression; Airway smooth muscle cell contraction; Pleural mesothelioma; Alzheimer's disease; GDNF signaling; Calcium regulation in cardiac cells"	"25"	"0"	"13.1"	"7.7"	"10.4"	"8.7"	"19.7"	"15.9"	"7.3"	"20.8"	"12.8"	"29.5"	"56.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WVM8"	"Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4"	"0.000"	""	"6"	"2"	"3"	"2"	"642"	"72.3"	"6.27"	"606.14"	"2.99"	"2"	"1"	"stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi"	"other molecular function"	"Pf00995"	"23256"	"ENSG00000092108"	"SCFD1"	"A8K2Z5; B7Z4U7; B7Z594; hsa:23256; O60754; O94990; Q7Z529; Q8WVM8; Q9BZI3; Q9UNL3; Q9Y6A8"	"RHOA GTPase cycle; COPII-mediated vesicle transport"	""	"2"	"0"	"8.1"	"4.1"	"8.8"	"6.0"	"11.7"	"11.4"	"11.3"	"10.0"	"9.2"	"15.2"	"29.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BSG0"	"Protease-associated domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PRADC1 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"188"	"21.0"	"5.47"	"416.35"	"2.99"	"1"	"1"	""	"non-structural extracellular"	""	"Pf02225"	"84279"	"ENSG00000135617"	"PRADC1"	"hsa:84279; Q2Z1P2; Q9BSG0"	""	""	"0"	"0"	"63.2"	"29.5"	"74.5"	"58.7"	"59.7"	"71.5"	"56.8"	"64.3"	"45.1"	"67.3"	"87.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6PII3"	"Coiled-coil domain-containing protein 174 OS=Homo sapiens OX=9606 GN=CCDC174 PE=1 SV=3"	"0.000"	""	"5"	"2"	"3"	"2"	"467"	"53.9"	"6.33"	"797.49"	"2.98"	"2"	"1"	""	"nucleus"	""	"Pf13300"	"51244"	"ENSG00000154781"	"CCDC174"	"hsa:51244; Q6PII3; Q96CS5"	""	""	"0"	"0"	"62.2"	"31.8"	"65.7"	"55.9"	"69.3"	"66.6"	"44.6"	"77.2"	"61.1"	"121.3"	"171.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49916"	"DNA ligase 3 OS=Homo sapiens OX=9606 GN=LIG3 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1009"	"112.8"	"9.01"	"332.89"	"2.98"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00645, Pf01068, Pf04675, Pf04679, Pf16759"	"3980"	"ENSG00000005156"	"LIG3"	"E5KLB5; E5KLB6; hsa:3980; P49916; Q16714; Q6NVK3"	"HDR through MMEJ (alt-NHEJ); Gap-filling DNA repair synthesis and ligation in TC-NER; Gap-filling DNA repair synthesis and ligation in GG-NER; APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway; Resolution of AP sites via the single-nucleotide replacement pathway"	"Base excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; 17q12 copy number variation syndrome"	"9"	"0"	"21.7"	"10.6"	"18.4"	"11.4"	"12.2"	"18.8"	"22.5"	"26.4"	"23.0"	"29.4"	"39.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NZQ3"	"NCK-interacting protein with SH3 domain OS=Homo sapiens OX=9606 GN=NCKIPSD PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"722"	"78.9"	"6.38"	"323.03"	"2.97"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;cytoskeleton;nucleus"	"cytoskeletal activity;other molecular function"	"Pf00018, Pf09431"	"51517"	"ENSG00000213672"	"NCKIPSD"	"B4DFL5; hsa:51517; Q6GU34; Q6SPF3; Q8TC10; Q9NZQ3; Q9UGM8"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs"	""	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51452"	"Dual specificity protein phosphatase 3 OS=Homo sapiens OX=9606 GN=DUSP3 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"185"	"20.5"	"7.80"	"351.42"	"2.97"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00782"	"1845"	"ENSG00000108861"	"DUSP3"	"D3DX45; hsa:1845; P51452; Q5U0J1; Q8IYJ9"	"ERKs are inactivated"	"MAPK signaling pathway; Fragile X syndrome"	"3"	"0"	"18.5"	"7.2"	"15.5"	"14.3"	"18.6"	"21.2"	"14.8"	"24.1"	"21.6"	"43.0"	"66.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQC6"	"Ribosomal protein 63, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL57 PE=1 SV=1"	"0.000"	""	"13"	"1"	"2"	"1"	"102"	"12.3"	"11.44"	"314.40"	"2.97"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf14978"	"78988"	"ENSG00000173141"	"MRPL57"	"A2A332; hsa:78988; Q9BQC6"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"28.8"	"10.9"	"26.2"	"29.7"	"30.1"	"37.1"	"27.2"	"32.4"	"30.5"	"65.0"	"153.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96SB4"	"SRSF protein kinase 1 OS=Homo sapiens OX=9606 GN=SRPK1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"655"	"74.3"	"6.16"	"402.53"	"2.97"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"6732"	"ENSG00000096063"	"SRPK1"	"B4DS61; hsa:6732; Q12890; Q5R364; Q5R365; Q8IY12; Q96SB4"	"Maturation of nucleoprotein"	"VEGFA-VEGFR2 signaling; mRNA processing"	"3"	"0"	"53.8"	"26.0"	"66.1"	"53.7"	"51.0"	"62.7"	"39.5"	"55.7"	"36.0"	"83.9"	"165.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H9C1"	"Spermatogenesis-defective protein 39 homolog OS=Homo sapiens OX=9606 GN=VIPAS39 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"493"	"57.0"	"7.40"	"364.23"	"2.97"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf04840"	"63894"	"ENSG00000151445"	"VIPAS39"	"B4DPI6; hsa:63894; O95434; Q9H7E1; Q9H9C1; Q9H9I9"	""	""	"0"	"0"	"63.2"	"30.7"	"58.3"	"55.3"	"51.4"	"58.2"	"43.5"	"58.5"	"63.6"	"152.4"	"256.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2U8"	"Inner nuclear membrane protein Man1 OS=Homo sapiens OX=9606 GN=LEMD3 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"911"	"99.9"	"7.55"	"420.98"	"2.96"	"1"	"1"	"other biological processes"	"other membranes;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03020, Pf09402"	"23592"	"ENSG00000174106"	"LEMD3"	"hsa:23592; Q9NT47; Q9NYA5; Q9Y2U8"	"RND3 GTPase cycle; RND2 GTPase cycle; RAC1 GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOD GTPase cycle; RND1 GTPase cycle; Initiation of Nuclear Envelope (NE) Reformation; Depolymerization of the Nuclear Lamina"	"Envelope proteins and their potential roles in EDMD physiopathology"	"12"	"0"	"59.2"	"27.4"	"35.6"	"33.7"	"41.8"	"44.4"	"39.4"	"60.7"	"73.4"	"317.8"	"768.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P54819"	"Adenylate kinase 2, mitochondrial OS=Homo sapiens OX=9606 GN=AK2 PE=1 SV=2"	"0.000"	""	"5"	"1"	"2"	"1"	"239"	"26.5"	"7.81"	"319.28"	"2.96"	"1"	"1"	"other metabolic processes"	"cytoskeleton;mitochondrion;other cell component"	"kinase activity;other molecular function"	"Pf00406, Pf05191"	"204"	"ENSG00000004455"	"AK2"	"A8K6L1; B4DHH7; B4DL64; hsa:204; P54819; Q16856; Q5EB54; Q5TIF7; Q8TCY2; Q8TCY3"	"Interconversion of nucleotide di- and triphosphates"	""	"1"	"0"	"35.0"	"14.1"	"20.8"	"19.6"	"31.5"	"28.1"	"26.3"	"30.3"	"29.5"	"63.8"	"111.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NBJ5"	"Procollagen galactosyltransferase 1 OS=Homo sapiens OX=9606 GN=COLGALT1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"622"	"71.6"	"7.31"	"301.84"	"2.96"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"ER/Golgi"	"other molecular function"	"Pf01755, Pf13704"	"79709"	"ENSG00000130309"	"COLGALT1"	"hsa:79709; Q8NBJ5; Q8NC64"	"Collagen biosynthesis and modifying enzymes"	"Type I collagen synthesis in the context of osteogenesis imperfecta"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42765"	"3-ketoacyl-CoA thiolase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAA2 PE=1 SV=2"	"0.001"	""	"2"	"1"	"2"	"1"	"397"	"41.9"	"8.09"	"234.15"	"2.95"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;transport"	"mitochondrion"	"other molecular function"	"Pf00108, Pf02803"	"10449"	"ENSG00000167315"	"ACAA2"	"hsa:10449; P42765; Q9BUT6"	"Mitochondrial Fatty Acid Beta-Oxidation"	"Fatty acid biosynthesis"	"2"	"0"	"80.9"	"42.5"	"81.9"	"71.3"	"71.2"	"79.6"	"74.6"	"91.5"	"67.2"	"311.4"	"768.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NE86"	"Calcium uniporter protein, mitochondrial OS=Homo sapiens OX=9606 GN=MCU PE=1 SV=1"	"0.002"	""	"3"	"1"	"2"	"1"	"351"	"39.8"	"8.65"	"230.27"	"2.95"	"1"	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf04678"	"90550"	"ENSG00000156026"	"MCU"	"B2RDF3; B3KXV7; hsa:90550; Q8NE86; Q96FL3"	"Processing of SMDT1"	"Alzheimer's disease and miRNA effects; Pleural mesothelioma; Alzheimer's disease"	"5"	"0"	"11.4"	"5.1"	"12.2"	"7.4"	"12.0"	"11.5"	"8.9"	"16.2"	"18.1"	"21.0"	"31.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75531"	"Barrier-to-autointegration factor OS=Homo sapiens OX=9606 GN=BANF1 PE=1 SV=1"	"0.000"	""	"13"	"1"	"2"	"1"	"89"	"10.1"	"6.09"	"367.91"	"2.94"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02961"	"8815"	"ENSG00000175334"	"BANF1"	"hsa:8815; O60558; O75531; Q6FGG7"	"Vpr-mediated nuclear import of PICs; 2-LTR circle formation; Integration of viral DNA into host genomic DNA; Autointegration results in viral DNA circles; APOBEC3G mediated resistance to HIV-1 infection; Nuclear Envelope Breakdown; Initiation of Nuclear Envelope (NE) Reformation"	"Envelope proteins and their potential roles in EDMD physiopathology; Familial partial lipodystrophy; Progeria-associated lipodystrophy"	"11"	"0"	"57.9"	"24.8"	"39.8"	"30.6"	"40.2"	"38.9"	"49.5"	"61.7"	"88.4"	"118.5"	"156.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EY7"	"Pentatricopeptide repeat domain-containing protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=PTCD3 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"689"	"78.5"	"6.42"	"380.72"	"2.94"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;translational apparatus;nucleus"	"translation activity;nucleic acid binding activity"	"Pf13041, Pf13812"	"55037"	"ENSG00000132300"	"PTCD3"	"A6NHD2; D6W5M1; hsa:55037; Q597H0; Q658Y9; Q96EY7; Q9BUZ8; Q9NWL0"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"23.6"	"9.7"	"26.0"	"19.7"	"23.1"	"26.1"	"15.4"	"24.5"	"30.5"	"68.4"	"362.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UL03"	"Integrator complex subunit 6 OS=Homo sapiens OX=9606 GN=INTS6 PE=1 SV=1"	"0.001"	""	"1"	"1"	"2"	"1"	"887"	"100.3"	"8.62"	"268.86"	"2.93"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus"	"other molecular function"	"Pf13519, Pf15300"	"26512"	"ENSG00000102786"	"INTS6"	"hsa:26512; Q0P664; Q6PJP4; Q9UFK0; Q9UL03; Q9Y5M9"	"RNA polymerase II transcribes snRNA genes"	""	"1"	"0"	"14.0"	"3.5"	"8.9"	"11.3"	"13.6"	"12.0"	"8.3"	"11.3"	"11.0"	"18.9"	"36.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NXW9"	"Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 OS=Homo sapiens OX=9606 GN=ALKBH4 PE=1 SV=1"	"0.000"	""	"7"	"2"	"3"	"2"	"302"	"33.8"	"6.67"	"596.96"	"2.93"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"cytoskeletal activity;other molecular function"	""	"54784"	"ENSG00000160993"	"ALKBH4"	"hsa:54784; Q53H92; Q9H6A4; Q9NXW9"	""	""	"0"	"0"	"86.3"	"41.4"	"76.7"	"73.3"	"67.1"	"100.7"	"64.0"	"91.2"	"86.3"	"282.9"	"654.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BXY0"	"Protein MAK16 homolog OS=Homo sapiens OX=9606 GN=MAK16 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"300"	"35.3"	"5.38"	"331.15"	"2.93"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf01778, Pf04874"	"84549"	"ENSG00000198042"	"MAK16"	"B2RB44; hsa:84549; Q5U5T1; Q86UC4; Q96SY6; Q9BXY0"	""	""	"0"	"0"	"27.0"	"14.6"	"28.4"	"22.3"	"24.9"	"26.7"	"23.3"	"36.3"	"26.2"	"56.0"	"68.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UHB9"	"Signal recognition particle subunit SRP68 OS=Homo sapiens OX=9606 GN=SRP68 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"627"	"70.7"	"8.56"	"300.21"	"2.93"	"1"	"1"	"transport;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf16969"	"6730"	"ENSG00000167881"	"SRP68"	"B3KUU5; B3KWY7; G3V1U4; hsa:6730; Q8NCJ4; Q8WUK2; Q9UHB9"	"SRP-dependent cotranslational protein targeting to membrane"	""	"1"	"0"	"37.5"	"10.7"	"27.5"	"24.1"	"27.2"	"32.1"	"24.6"	"37.4"	"28.7"	"50.5"	"124.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z739"	"YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1"	"0.000"	""	"4"	"3"	"4"	"2"	"585"	"63.8"	"9.04"	"912.23"	"2.92"	"3"	"1"	"cell organization and biogenesis;other biological processes"	"cytosol;other cell component"	"translation activity;nucleic acid binding activity"	"Pf04146"	"253943"	"ENSG00000185728"	"YTHDF3"	"B3KXL4; hsa:253943; Q63Z37; Q659A3; Q7Z739"	""	""	"0"	"0"	"381.5"	"184.2"	"417.8"	"350.7"	"364.6"	"458.4"	"310.7"	"416.7"	"303.5"	"579.0"	"682.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P035"	"Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 OS=Homo sapiens OX=9606 GN=HACD3 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"362"	"43.1"	"8.94"	"318.32"	"2.92"	"1"	"1"	"other metabolic processes;stress response;signal transduction;other biological processes"	"other membranes;ER/Golgi;nucleus"	"enzyme regulator activity;other molecular function"	"Pf04387"	"51495"	"ENSG00000074696"	"HACD3"	"A0PJA1; B4DRF4; hsa:51495; Q280Z3; Q6PD63; Q8IUI5; Q8NC86; Q8NCB1; Q96T12; Q9NQA7; Q9P035"	"Synthesis of very long-chain fatty acyl-CoAs"	""	"1"	"0"	"97.2"	"33.5"	"65.6"	"58.6"	"74.3"	"81.5"	"59.4"	"82.1"	"111.7"	"188.2"	"412.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15287"	"RNA-binding protein with serine-rich domain 1 OS=Homo sapiens OX=9606 GN=RNPS1 PE=1 SV=1"	"0.000"	""	"5"	"2"	"3"	"2"	"305"	"34.2"	"11.84"	"501.49"	"2.91"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"10921"	"ENSG00000205937"	"RNPS1"	"A8K1P0; B4DDU8; B4DZU7; B7ZA17; hsa:10921; O75308; Q15287; Q32P25; Q8WY42; Q9NYG3"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"mRNA processing"	"7"	"0"	"693.8"	"151.2"	"283.1"	"239.9"	"315.1"	"296.3"	"294.3"	"408.4"	"298.4"	"570.0"	"1155.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P58546"	"Myotrophin OS=Homo sapiens OX=9606 GN=MTPN PE=1 SV=2"	"0.001"	""	"6"	"1"	"2"	"1"	"118"	"12.9"	"5.52"	"285.47"	"2.91"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity"	"Pf12796"	"136319"	"ENSG00000105887"	"MTPN"	"hsa:136319; P58546"	""	""	"0"	"0"	"69.7"	"28.2"	"46.8"	"40.6"	"54.7"	"51.1"	"49.2"	"58.3"	"50.9"	"90.2"	"165.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NFH5"	"Nucleoporin NUP35 OS=Homo sapiens OX=9606 GN=NUP35 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"326"	"34.8"	"9.09"	"359.58"	"2.90"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf05172"	"129401"	"ENSG00000163002"	"NUP35"	"B4DP57; B4DYB4; hsa:129401; Q4ZFZ9; Q53S95; Q8NFH5; Q8TDJ1"	"Transport of Mature mRNA Derived from an Intronless Transcript; tRNA processing in the nucleus; SUMOylation of RNA binding proteins; Regulation of HSF1-mediated heat shock response; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of DNA replication proteins; Postmitotic nuclear pore complex (NPC) reformation; Transport of Mature mRNA derived from an Intron-Containing Transcript; SARS-CoV-2 activates/modulates innate and adaptive immune responses; HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; Nuclear Pore Complex (NPC) Disassembly; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"	""	"29"	"0"	"56.9"	"28.7"	"53.6"	"44.9"	"53.6"	"48.4"	"41.3"	"48.3"	"53.6"	"87.3"	"105.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WVD3"	"E3 ubiquitin-protein ligase RNF138 OS=Homo sapiens OX=9606 GN=RNF138 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"245"	"28.2"	"6.93"	"344.27"	"2.90"	"1"	"1"	"cell-cell signaling;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05605, Pf13923, Pf18574"	"51444"	"ENSG00000134758"	"RNF138"	"B2RE17; hsa:51444; Q8WVD3; Q9H8K2; Q9UF87; Q9UKI6"	"Antigen processing: Ubiquitination & Proteasome degradation"	""	"1"	"0"	"66.4"	"39.5"	"71.7"	"62.9"	"63.0"	"79.8"	"56.8"	"94.8"	"195.6"	"538.3"	"508.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13206"	"Probable ATP-dependent RNA helicase DDX10 OS=Homo sapiens OX=9606 GN=DDX10 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"875"	"100.8"	"8.63"	"321.38"	"2.90"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00270, Pf00271, Pf13959"	"1662"	"ENSG00000178105"	"DDX10"	"B2RCQ3; hsa:1662; Q13206; Q5BJD8"	""	""	"0"	"0"	"17.6"	"3.5"	"13.9"	"16.2"	"11.9"	"17.9"	"12.7"	"16.6"	"14.2"	"27.4"	"45.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01968"	"Inositol polyphosphate 5-phosphatase OCRL OS=Homo sapiens OX=9606 GN=OCRL PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"901"	"104.1"	"6.55"	"337.23"	"2.89"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00620, Pf03372, Pf16726"	"4952"	"ENSG00000122126"	"OCRL"	"A6NKI1; A8KAP2; B7ZLX2; hsa:4952; O60800; Q01968; Q15684; Q15774; Q4VY09; Q4VY10; Q5JQF1; Q5JQF2; Q9UJG5; Q9UMA5"	"Clathrin-mediated endocytosis; RAC3 GTPase cycle; RHOJ GTPase cycle; Golgi Associated Vesicle Biogenesis; Synthesis of PIPs at the plasma membrane; Synthesis of PIPs at the Golgi membrane; Synthesis of IP2, IP, and Ins in the cytosol; Synthesis of IP3 and IP4 in the cytosol"	"VEGFA-VEGFR2 signaling; Ciliopathies; Bardet-Biedl syndrome"	"11"	"0"	"72.0"	"38.4"	"62.8"	"68.5"	"74.7"	"78.4"	"55.6"	"102.1"	"142.6"	"366.7"	"536.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y3T9"	"Nucleolar complex protein 2 homolog OS=Homo sapiens OX=9606 GN=NOC2L PE=1 SV=4"	""	""	"1"	"1"	"1"	"1"	"749"	"84.9"	"5.62"	""	"2.89"	""	"1"	"cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf03715"	"26155"	"ENSG00000188976"	"NOC2L"	"hsa:26155; Q5SVA3; Q9BTN6; Q9Y3T9"	"Regulation of TP53 Activity through Phosphorylation"	"1p36 copy number variation syndrome"	"2"	"0"	"142.4"	"83.9"	"114.7"	"97.0"	"160.4"	"222.2"	"135.9"	"169.1"	"143.3"	"221.2"	"265.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13861"	"cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"404"	"45.5"	"5.07"	"374.38"	"2.88"	"1"	"1"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00027, Pf02197"	"5576"	"ENSG00000114302"	"PRKAR2A"	"hsa:5576; P13861; Q16823; Q9BUB1"	"Factors involved in megakaryocyte development and platelet production; GPER1 signaling; FCGR3A-mediated IL10 synthesis; ADORA2B mediated anti-inflammatory cytokines production; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Vasopressin regulates renal water homeostasis via Aquaporins; PKA activation; PKA activation in glucagon signalling; Hedgehog 'off' state; DARPP-32 events; CREB1 phosphorylation through the activation of Adenylate Cyclase; ROBO receptors bind AKAP5"	"Myometrial relaxation and contraction pathways; G protein signaling pathways; Lipid metabolism pathway; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; GDNF signaling; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"20"	"0"	"106.3"	"46.7"	"71.4"	"53.6"	"78.5"	"79.0"	"69.5"	"81.4"	"100.4"	"156.3"	"297.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75165"	"DnaJ homolog subfamily C member 13 OS=Homo sapiens OX=9606 GN=DNAJC13 PE=1 SV=5"	"0.000"	""	"1"	"1"	"2"	"1"	"2243"	"254.3"	"6.74"	"342.15"	"2.88"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	""	"Pf00226, Pf14237, Pf19432"	"23317"	"ENSG00000138246"	"DNAJC13"	"hsa:23317; O75165; Q3L0T1; Q6PI82; Q6UJ77; Q6ZSW1; Q6ZUT5; Q86XG3; Q96DC1; Q9BWK9"	"Neutrophil degranulation"	""	"1"	"0"	"13.1"	"3.9"	"9.1"	"6.1"	"8.0"	"8.2"	"8.2"	"10.4"	"11.6"	"19.1"	"40.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q86TN4"	"tRNA 2'-phosphotransferase 1 OS=Homo sapiens OX=9606 GN=TRPT1 PE=1 SV=2"	""	""	"4"	"1"	"1"	"1"	"253"	"27.7"	"9.98"	""	"2.88"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	""	"other molecular function"	"Pf01885"	"83707"	"ENSG00000149743"	"TRPT1"	"A8MU17; A8MYC9; F5H2B2; hsa:83707; Q86TN4; Q9BSB9"	""	""	"0"	"0"	"16.8"	"4.4"	"16.9"	"12.2"	"13.0"	"14.1"	"12.2"	"19.7"	"45.5"	"156.1"	"315.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30041"	"Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3"	"0.000"	""	"5"	"1"	"2"	"1"	"224"	"25.0"	"6.38"	"412.77"	"2.88"	"1"	"1"	"other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00578, Pf10417"	"9588"	"ENSG00000117592"	"PRDX6"	"A8JZY7; hsa:9588; P30041; P32077; Q5TAH4; Q5ZEZ8"	"Neutrophil degranulation; Detoxification of Reactive Oxygen Species"	"Nuclear receptors meta-pathway; NRF2 pathway; VEGFA-VEGFR2 signaling"	"5"	"0"	"81.3"	"33.0"	"61.4"	"33.9"	"53.4"	"55.3"	"51.3"	"63.8"	"68.8"	"111.1"	"212.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P56556"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 OS=Homo sapiens OX=9606 GN=NDUFA6 PE=1 SV=4"	"0.000"	""	"8"	"1"	"2"	"1"	"128"	"15.1"	"9.98"	"306.71"	"2.87"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf05347"	"4700"	"ENSG00000184983; ENSG00000272765; ENSG00000273397; ENSG00000277365; ENSG00000281013"	"NDUFA6"	"B2RE54; hsa:4700; O43675; P56556; Q6FGW0; Q6IBT8; Q6IC39"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"5"	"0"	"106.3"	"40.4"	"115.3"	"101.4"	"97.8"	"120.6"	"79.6"	"112.7"	"71.4"	"322.9"	"729.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14676"	"Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3"	"0.000"	""	"0"	"1"	"2"	"1"	"2089"	"226.5"	"5.47"	"335.08"	"2.86"	"1"	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	""	"Pf00498, Pf16770"	"9656"	"ENSG00000137337; ENSG00000206481; ENSG00000224587; ENSG00000225589; ENSG00000228575; ENSG00000231135; ENSG00000234012; ENSG00000237095"	"MDC1"	"A2AB04; A2BF04; A2RRA8; A7YY86; B0S8A2; hsa:9656; Q0EFC2; Q14676; Q2L6H7; Q2TAZ4; Q5JP55; Q5JP56; Q5ST83; Q68CQ3; Q86Z06; Q96QC2"	"Processing of DNA double-strand break ends; SUMOylation of DNA damage response and repair proteins; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; TP53 Regulates Transcription of DNA Repair Genes; G2/M DNA damage checkpoint; Nonhomologous End-Joining (NHEJ)"	"ATM signaling in development and disease ; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; NIPBL role in DNA damage - Cornelia de Lange syndrome"	"9"	"0"	"103.4"	"34.6"	"66.2"	"33.6"	"51.9"	"72.2"	"60.5"	"90.7"	"80.8"	"113.1"	"224.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15126"	"Phosphomevalonate kinase OS=Homo sapiens OX=9606 GN=PMVK PE=1 SV=3"	"0.001"	""	"7"	"1"	"2"	"1"	"192"	"22.0"	"5.73"	"266.88"	"2.86"	"1"	"1"	"other metabolic processes;other biological processes"	"cytosol;other cytoplasmic organelle"	"kinase activity;other molecular function"	"Pf04275"	"10654"	"ENSG00000163344"	"PMVK"	"hsa:10654; Q15126; Q5TZW9"	"Activation of gene expression by SREBF (SREBP); Cholesterol biosynthesis"	"Cholesterol biosynthesis pathway; Mevalonate pathway; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Cholesterol synthesis disorders; Cholesterol metabolism; Enterocyte cholesterol metabolism"	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULX6"	"A-kinase anchor protein 8-like OS=Homo sapiens OX=9606 GN=AKAP8L PE=1 SV=4"	"0.001"	""	"2"	"1"	"2"	"1"	"646"	"71.6"	"5.05"	"284.90"	"2.86"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04988"	"26993"	"ENSG00000011243"	"AKAP8L"	"B4DJ74; B5BU90; hsa:26993; O94792; Q96J58; Q9NRQ0; Q9UGM0; Q9ULX6"	"Formation of WDR5-containing histone-modifying complexes"	""	"1"	"0"	"23.6"	"11.7"	"16.6"	"17.6"	"16.3"	"20.0"	"20.3"	"22.5"	"21.0"	"33.7"	"56.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O96008"	"Mitochondrial import receptor subunit TOM40 homolog OS=Homo sapiens OX=9606 GN=TOMM40 PE=1 SV=1"	"0.001"	""	"3"	"1"	"2"	"1"	"361"	"37.9"	"7.25"	"275.83"	"2.85"	"1"	"1"	"cell organization and biogenesis;transport"	"other membranes;cytosol;mitochondrion;other cell component"	"transporter activity"	"Pf01459"	"10452"	"ENSG00000130204"	"TOMM40"	"A0A024R0P9; hsa:10452; O96008; Q86VW4; Q8WY09; Q8WY10; Q8WY11; Q9BR95"	"Mitochondrial protein import; PINK1-PRKN Mediated Mitophagy"	"IL-18 signaling pathway"	"3"	"0"	"22.7"	"5.6"	"11.3"	"5.9"	"10.4"	"10.3"	"9.0"	"14.4"	"14.8"	"21.2"	"61.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NPI1"	"Bromodomain-containing protein 7 OS=Homo sapiens OX=9606 GN=BRD7 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"651"	"74.1"	"6.39"	"298.58"	"2.85"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00439, Pf12024"	"29117"	"ENSG00000166164"	"BRD7"	"hsa:29117; Q4VC09; Q8N2L9; Q96KA4; Q9BV48; Q9NPI1; Q9UH59"	"Regulation of TP53 Activity through Acetylation"	""	"1"	"0"	"12.5"	"0.0"	"4.7"	"7.3"	"8.3"	"9.5"	"5.5"	"7.1"	"5.1"	"19.4"	"36.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6G9"	"Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens OX=9606 GN=DYNC1LI1 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"523"	"56.5"	"6.42"	"359.84"	"2.85"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf05783"	"51143"	"ENSG00000144635"	"DYNC1LI1"	"A2RRG7; hsa:51143; Q53HC8; Q53HK7; Q9Y6G9"	"Separation of Sister Chromatids; Neutrophil degranulation; HCMV Early Events; RHO GTPases Activate Formins; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Aggrephagy; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein"	"15"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O00178"	"GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=GTPBP1 PE=1 SV=3"	""	""	"2"	"1"	"1"	"1"	"669"	"72.4"	"8.34"	""	"2.85"	""	"1"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;other cytoplasmic organelle"	"nucleic acid binding activity;other molecular function"	"Pf00009"	"9567"	"ENSG00000100226"	"GTPBP1"	"hsa:9567; O00178; Q6IC67"	""	""	"0"	"0"	"16.9"	"10.2"	"18.0"	"15.6"	"19.2"	"19.9"	"13.0"	"20.4"	"17.0"	"32.2"	"56.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P587"	"Acylpyruvase FAHD1, mitochondrial OS=Homo sapiens OX=9606 GN=FAHD1 PE=1 SV=2"	"0.000"	""	"6"	"1"	"2"	"1"	"224"	"24.8"	"7.39"	"415.23"	"2.84"	"1"	"1"	"other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf01557"	"81889"	"ENSG00000180185"	"FAHD1"	"B1AK40; B1AK41; hsa:81889; Q6FIC7; Q6P587; Q96RY1; Q9H0N6"	"Citric acid cycle (TCA cycle)"	""	"1"	"0"	"55.8"	"23.7"	"37.4"	"39.9"	"46.6"	"51.9"	"34.8"	"47.9"	"50.0"	"119.5"	"326.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96MU7"	"YTH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=YTHDC1 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"727"	"84.6"	"6.23"	"360.98"	"2.83"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;nucleus"	"nucleic acid binding activity"	"Pf04146"	"91746"	"ENSG00000083896; ENSG00000275272"	"YTHDC1"	"hsa:91746; Q4W5Q3; Q7Z622; Q8TF35; Q96MU7"	""	""	"0"	"0"	"146.9"	"60.1"	"104.6"	"109.7"	"111.7"	"111.0"	"94.9"	"161.1"	"93.6"	"210.8"	"435.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WWM7"	"Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2"	"0.001"	""	"1"	"1"	"2"	"1"	"1075"	"113.3"	"8.59"	"239.23"	"2.83"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf06741, Pf07145, Pf14438"	"11273"	"ENSG00000168488"	"ATXN2L"	"A8K1R6; B9EGM2; E9PAR9; hsa:11273; O95135; Q63ZY4; Q6NVJ8; Q6PJW6; Q8IU61; Q8IU95; Q8WWM3; Q8WWM4; Q8WWM5; Q8WWM6; Q8WWM7; Q99703"	""	"16p11.2 distal deletion syndrome"	"1"	"0"	"129.6"	"53.6"	"117.5"	"98.2"	"131.3"	"125.5"	"98.0"	"118.8"	"104.0"	"235.1"	"341.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P52333"	"Tyrosine-protein kinase JAK3 OS=Homo sapiens OX=9606 GN=JAK3 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1124"	"125.0"	"7.18"	""	"2.82"	""	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cytoplasmic organelle"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf07714, Pf17887, Pf18377, Pf18379"	"3718"	"ENSG00000105639"	"JAK3"	"hsa:3718; P52333; Q13259; Q13260; Q13611; Q8N1E8; Q99699; Q9Y6S2"	"Potential therapeutics for SARS; Interleukin receptor SHC signaling; RAF/MAP kinase cascade; Interleukin-7 signaling; Signaling by ALK; Interleukin-4 and Interleukin-13 signaling; Interleukin-20 family signaling; Interleukin-2 signaling; Interleukin-15 signaling; Interleukin-9 signaling; Interleukin-21 signaling"	"IL-7 signaling pathway; IL-9 signaling pathway; Oncostatin M signaling pathway; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; IL-4 signaling pathway; PI3K-Akt signaling pathway; Non-small cell lung cancer; ncRNAs involved in STAT3 signaling in hepatocellular carcinoma; Measles virus infection; Hepatitis B infection; IL-2 signaling pathway"	"23"	"0"	"78.5"	"30.3"	"55.1"	"41.6"	"58.2"	"64.9"	"58.1"	"94.4"	"112.5"	"382.5"	"946.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9BXC9"	"Bardet-Biedl syndrome 2 protein OS=Homo sapiens OX=9606 GN=BBS2 PE=1 SV=1"	""	""	"1"	"1"	"1"	"1"	"721"	"79.8"	"6.15"	""	"2.81"	""	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"39.2"	"19.1"	"39.2"	"32.1"	"32.2"	"45.2"	"39.0"	"54.7"	"84.9"	"204.0"	"352.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16718"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 OS=Homo sapiens OX=9606 GN=NDUFA5 PE=1 SV=3"	"0.001"	""	"9"	"1"	"2"	"1"	"116"	"13.5"	"5.99"	"273.00"	"2.81"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf04716"	"4698"	"ENSG00000128609"	"NDUFA5"	"B2RD98; hsa:4698; Q16718; Q5H9R2; Q6IRX7"	"Complex I biogenesis; RHOG GTPase cycle"	"Electron transport chain: OXPHOS system in mitochondria; Ciliary landscape; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"7"	"0"	"37.2"	"10.7"	"27.8"	"24.2"	"41.2"	"34.3"	"31.2"	"34.6"	"29.5"	"66.1"	"155.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92890"	"Ubiquitin recognition factor in ER-associated degradation protein 1 OS=Homo sapiens OX=9606 GN=UFD1 PE=1 SV=3"	"0.001"	""	"3"	"1"	"2"	"1"	"307"	"34.5"	"6.70"	"253.07"	"2.81"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf03152"	"7353"	"ENSG00000070010"	"UFD1"	"A8MW31; hsa:7353; Q92890; Q9Y5N0"	"Ub-specific processing proteases; Neddylation; KEAP1-NFE2L2 pathway; Translesion Synthesis by POLH"	"22q11.2 copy number variation syndrome"	"5"	"0"	"25.7"	"13.9"	"17.4"	"19.5"	"20.3"	"26.0"	"19.6"	"20.1"	"18.5"	"32.2"	"54.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UEE9"	"Craniofacial development protein 1 OS=Homo sapiens OX=9606 GN=CFDP1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"299"	"33.6"	"4.81"	"361.62"	"2.81"	"1"	"1"	"cell adhesion;cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	""	"Pf07572"	"10428"	"ENSG00000153774"	"CFDP1"	"hsa:10428; O00393; O00404; Q9UEE9; Q9UEF0; Q9UEF1; Q9UEF8"	""	""	"0"	"0"	"106.1"	"56.8"	"95.1"	"93.2"	"98.8"	"113.4"	"99.9"	"140.5"	"115.9"	"157.2"	"231.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07737"	"Profilin-1 OS=Homo sapiens OX=9606 GN=PFN1 PE=1 SV=2"	"0.001"	""	"11"	"1"	"2"	"1"	"140"	"15.0"	"8.27"	"260.70"	"2.80"	"1"	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00235"	"5216"	"ENSG00000108518"	"PFN1"	"hsa:5216; P07737; Q53Y44"	"RHO GTPases Activate Formins; Platelet degranulation ; PCP/CE pathway; Signaling by ROBO receptors"	"Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Burn wound healing; Regulation of actin cytoskeleton; G13 signaling pathway"	"9"	"0"	"44.6"	"27.4"	"28.7"	"14.5"	"27.0"	"27.5"	"24.8"	"28.2"	"39.5"	"63.3"	"248.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z478"	"ATP-dependent RNA helicase DHX29 OS=Homo sapiens OX=9606 GN=DHX29 PE=1 SV=2"	"0.000"	""	"2"	"2"	"3"	"2"	"1369"	"155.1"	"8.09"	"632.73"	"2.80"	"2"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"54505"	"ENSG00000067248"	"DHX29"	"hsa:54505; O75549; Q63HN0; Q63HN3; Q7Z478; Q8IWW2; Q8N3A1; Q9UMH2"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"30.4"	"13.5"	"31.9"	"23.1"	"23.2"	"30.1"	"17.8"	"25.5"	"13.9"	"55.2"	"110.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13492"	"Phosphatidylinositol-binding clathrin assembly protein OS=Homo sapiens OX=9606 GN=PICALM PE=1 SV=2"	"0.000"	""	"3"	"2"	"2"	"2"	"652"	"70.7"	"7.90"	"410.25"	"2.80"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf07651"	"8301"	"ENSG00000073921"	"PICALM"	"B4DTM3; E9PN05; F8VPG7; hsa:8301; O60700; Q13492; Q4LE54; Q6GMQ6; Q86XZ9"	"Cargo recognition for clathrin-mediated endocytosis; Golgi Associated Vesicle Biogenesis; RND3 GTPase cycle"	""	"4"	"0"	"139.3"	"63.6"	"133.4"	"107.7"	"128.9"	"166.3"	"121.3"	"156.3"	"193.5"	"870.4"	"1652.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75151"	"Lysine-specific demethylase PHF2 OS=Homo sapiens OX=9606 GN=PHF2 PE=1 SV=4"	"0.000"	""	"1"	"1"	"2"	"1"	"1096"	"120.7"	"9.17"	"314.46"	"2.80"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00628, Pf02373, Pf17811"	"5253"	"ENSG00000197724"	"PHF2"	"hsa:5253; O75151; Q4VXG0; Q8N3K2; Q9Y6N4"	"HDMs demethylate histones"	""	"1"	"0"	"17.3"	"7.4"	"18.0"	"16.2"	"16.5"	"21.2"	"15.1"	"24.7"	"21.0"	"32.6"	"57.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15678"	"Tyrosine-protein phosphatase non-receptor type 14 OS=Homo sapiens OX=9606 GN=PTPN14 PE=1 SV=2"	"0.001"	""	"1"	"1"	"2"	"1"	"1187"	"135.2"	"8.31"	"248.04"	"2.79"	"1"	"1"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00102, Pf00373, Pf09379, Pf09380"	"5784"	"ENSG00000152104"	"PTPN14"	"hsa:5784; Q15678; Q5VSI0"	"Interleukin-37 signaling"	"VEGFA-VEGFR2 signaling"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P29374"	"AT-rich interactive domain-containing protein 4A OS=Homo sapiens OX=9606 GN=ARID4A PE=1 SV=3"	"0.001"	""	"1"	"1"	"2"	"1"	"1257"	"142.7"	"5.10"	"292.66"	"2.79"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01388, Pf08169, Pf11717"	"5926"	"ENSG00000032219"	"ARID4A"	"hsa:5926; P29374; Q15991; Q15992; Q15993"	"Potential therapeutics for SARS; HDACs deacetylate histones"	""	"2"	"0"	"25.2"	"7.4"	"14.6"	"10.1"	"15.2"	"19.9"	"20.9"	"32.9"	"21.1"	"28.2"	"42.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P48507"	"Glutamate--cysteine ligase regulatory subunit OS=Homo sapiens OX=9606 GN=GCLM PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"274"	"30.7"	"6.02"	"310.10"	"2.79"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00248"	"2730"	"ENSG00000023909"	"GCLM"	"A8K334; D3DT45; hsa:2730; M5A959; P48507; Q6FHC1; Q9NPX9; Q9NU74"	"Glutathione synthesis and recycling; NFE2L2 regulating anti-oxidant/detoxification enzymes; Defective GCLC causes HAGGSD"	"Glutathione metabolism; Trans-sulfuration pathway; Trans-sulfuration, one-carbon metabolism and related pathways; Nuclear receptors meta-pathway; NRF2 pathway; Transcriptional activation by NRF2 in response to phytochemicals; Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling; Amino acid metabolism; Ferroptosis; NRF2-ARE regulation; Antiviral and anti-inflammatory effects of Nrf2 on SARS-CoV-2 pathway"	"14"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NPB8"	"Glycerophosphocholine phosphodiesterase GPCPD1 OS=Homo sapiens OX=9606 GN=GPCPD1 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"672"	"76.0"	"5.53"	""	"2.78"	""	"1"	"other metabolic processes;other biological processes"	"cytosol"	"other molecular function"	"Pf00686, Pf03009"	"56261"	"ENSG00000125772"	"GPCPD1"	"D3DW06; hsa:56261; Q9BQL8; Q9NPB8; Q9NUX0"	"Hydrolysis of LPC; Hydrolysis of LPE"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6ZW49"	"PAX-interacting protein 1 OS=Homo sapiens OX=9606 GN=PAXIP1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1069"	"121.3"	"6.70"	"300.68"	"2.78"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	""	"Pf00533, Pf12738"	"22976"	"ENSG00000157212"	"PAXIP1"	"hsa:22976; O15404; Q6N099; Q6ZW49; Q6ZWH9; Q7Z315; Q86UN0; Q8N4P9; Q96HP2"	"Activation of anterior HOX genes in hindbrain development during early embryogenesis; Formation of WDR5-containing histone-modifying complexes; Nonhomologous End-Joining (NHEJ)"	"16p11.2 proximal deletion syndrome; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; Kleefstra syndrome"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15054"	"DNA polymerase delta subunit 3 OS=Homo sapiens OX=9606 GN=POLD3 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"466"	"51.4"	"9.35"	"305.35"	"2.78"	"1"	"1"	"DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf09507"	"10714"	"ENSG00000077514"	"POLD3"	"B7ZAI6; hsa:10714; Q15054; Q32MZ9; Q32N00"	"Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Polymerase switching on the C-strand of the telomere; Polymerase switching; Removal of the Flap Intermediate; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"Homologous recombination; Retinoblastoma gene in cancer; Pyrimidine metabolism; DNA replication; Base excision repair; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"26"	"0"	"73.6"	"31.5"	"67.5"	"60.8"	"64.4"	"73.4"	"77.1"	"123.4"	"98.8"	"171.3"	"232.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P23458"	"Tyrosine-protein kinase JAK1 OS=Homo sapiens OX=9606 GN=JAK1 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1154"	"133.2"	"7.55"	""	"2.78"	""	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf07714, Pf17887, Pf18377, Pf18379"	"3716"	"ENSG00000162434"	"JAK1"	"hsa:3716; P23458; Q59GQ2; Q9UD26"	"Potential therapeutics for SARS; ISG15 antiviral mechanism; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Interleukin receptor SHC signaling; RAF/MAP kinase cascade; Interleukin-7 signaling; Interleukin-10 signaling; Interleukin-4 and Interleukin-13 signaling; Interleukin-6 signaling; Regulation of IFNG signaling; Regulation of IFNA/IFNB signaling; Inactivation of CSF3 (G-CSF) signaling; MAPK3 (ERK1) activation; MAPK1 (ERK2) activation; IL-6-type cytokine receptor ligand interactions; Interleukin-20 family signaling; Interleukin-35 Signalling; Interleukin-12 signaling; Interleukin-27 signaling; IFNG signaling activates MAPKs; Interleukin-2 signaling; Other interleukin signaling; Interleukin-15 signaling; Interleukin-9 signaling; Interleukin-21 signaling"	"IL-5 signaling pathway; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Prolactin signaling pathway; IL-7 signaling pathway; IL-17 signaling pathway; Type III interferon signaling; IL-9 signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; Interleukin-11 signaling pathway; Oncostatin M signaling pathway; IL-3 signaling pathway; TCA cycle nutrient use and invasiveness of ovarian cancer; IL6 signaling pathway; Hepatitis C and hepatocellular carcinoma; Embryonic stem cell pluripotency pathways; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; IL-4 signaling pathway; PI3K-Akt signaling pathway; Immune response to tuberculosis; Pancreatic adenocarcinoma pathway; Acute viral myocarditis; ncRNAs involved in STAT3 signaling in hepatocellular carcinoma; Non-genomic actions of 1,25 dihydroxyvitamin D3; EGF/EGFR signaling pathway; IL-10 anti-inflammatory signaling pathway ; Overview of interferons-mediated signaling pathway; Measles virus infection; Hepatitis B infection; EGFR tyrosine kinase inhibitor resistance; TGF-beta receptor signaling in skeletal dysplasias; Type I interferon induction and signaling during SARS-CoV-2 infection; Host-pathogen interaction of human coronaviruses - interferon induction; IL-2 signaling pathway; SARS coronavirus and innate immunity; SARS-CoV-2 innate immunity evasion and cell-specific immune response; Neuroinflammation and glutamatergic signaling; Pleural mesothelioma; Th17 cell differentiation pathway; IL-26 signaling pathways; TGF-beta receptor signaling; Interferon type I signaling pathways; Type II interferon signaling"	"71"	"0"	"16.2"	"9.4"	"12.3"	"11.8"	"11.9"	"14.3"	"11.8"	"19.4"	"18.2"	"42.7"	"91.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61289"	"Proteasome activator complex subunit 3 OS=Homo sapiens OX=9606 GN=PSME3 PE=1 SV=1"	"0.000"	""	"7"	"2"	"3"	"2"	"254"	"29.5"	"5.95"	"842.63"	"2.78"	"2"	"1"	"cell cycle OR cell proliferation;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02251, Pf02252"	"10197"	"ENSG00000131467"	"PSME3"	"A8K9A3; hsa:10197; O35563; P61289; P97373; Q12920; Q13172; Q9BQD9"	"Regulation of expression of SLITs and ROBOs; ER-Phagosome pathway; Separation of Sister Chromatids; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation"	"60"	"0"	"318.0"	"119.8"	"295.4"	"252.2"	"307.1"	"403.1"	"344.9"	"495.8"	"367.5"	"799.0"	"1477.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NZZ3"	"Charged multivesicular body protein 5 OS=Homo sapiens OX=9606 GN=CHMP5 PE=1 SV=1"	""	""	"7"	"1"	"1"	"1"	"219"	"24.6"	"4.83"	""	"2.77"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	""	"Pf03357"	"51510"	"ENSG00000086065"	"CHMP5"	"B2RD95; B4DIR6; hsa:51510; Q5VXW2; Q96AV2; Q9HB68; Q9NYS4; Q9NZZ3; Q9Y323"	"Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT)"	"Ferroptosis"	"3"	"0"	"23.0"	"11.1"	"23.8"	"14.7"	"27.4"	"27.4"	"16.7"	"34.2"	"23.5"	"56.1"	"84.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P0U3"	"Sentrin-specific protease 1 OS=Homo sapiens OX=9606 GN=SENP1 PE=1 SV=2"	"0.001"	""	"1"	"1"	"2"	"1"	"644"	"73.4"	"8.47"	"289.66"	"2.77"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf02902"	"29843"	"ENSG00000079387"	"SENP1"	"A8K7P5; hsa:29843; Q86XC8; Q9P0U3"	"RHOF GTPase cycle; SUMO is proteolytically processed"	""	"2"	"0"	"82.7"	"46.4"	"70.2"	"75.3"	"61.8"	"75.7"	"74.4"	"84.2"	"82.1"	"203.7"	"303.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P16220"	"Cyclic AMP-responsive element-binding protein 1 OS=Homo sapiens OX=9606 GN=CREB1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"341"	"36.7"	"5.57"	"309.53"	"2.77"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00170, Pf02173"	"100351999; 100477711; 100586647; 100675162; 100974672; 101010524; 101356881; 101383024; 101608568; 101964691; 102141699; 102246867; 102428529; 102531048; 102748542; 103217717; 103744440; 104680220; 105468005; 105517357; 105549382; 105580103; 105864304; 106967098; 108540349; 109691946; 1385; 459901; 607922; 708717"	"ENSAMEG00000015152; ENSCAFG00000013510; ENSCAFG00030010510; ENSCAFG00040025786; ENSCAFG00845022020; ENSCANG00000030079; ENSCATG00000037133; ENSCCNG00000003127; ENSCSAG00000010111; ENSFCAG00000008220; ENSGGOG00000024394; ENSJJAG00000013846; ENSLAFG00000013257; ENSLCNG00005016477; ENSMFAG00000039629; ENSMICG00000009731; ENSMLEG00000033904; ENSMLUG00000016119; ENSMMMG00000014914; ENSMMUG00000022601; ENSMNEG00000030274; ENSNGAG00000018967; ENSNLEG00000007124; ENSOCUG00000005427; ENSPANG00000009083; ENSPLOG00000007090; ENSPPAG00000042817; ENSPPYG00000013115; ENSPTIG00000011848; ENSPTRG00000043959; ENSRBIG00000040701; ENSRFEG00010020193; ENSRROG00000035316; ENSSDAG00000020160; ENSSSCG00005034714; ENSSSCG00015008370; ENSSSCG00025020324; ENSSSCG00030035186; ENSSSCG00035079382; ENSSSCG00040036512; ENSSSCG00045023175; ENSSSCG00050037141; ENSSSCG00055008554; ENSSSCG00060058264; ENSSSCG00065052126; ENSSSCG00070020566; ENSSSUG00005001816; ENSSTOG00000016482; ENSSVLG00005003093; ENSTGEG00000004249; ENSUAMG00000018783; ENSUMAG00000022656; ENSUPAG00010007984; ENSVVUG00000011892"	"Creb1; CREB1; LOC101356881"	"A0A024R401; A0A096MS95; A0A0D9RCK8; A0A286ZWB0; A0A2I2YCF6; A0A2J8N5U5; A0A2J8WUF2; A0A2K5I9K2; A0A2K5MQP0; A0A2K5X536; A0A2K5X539; A0A2K5YUX5; A0A2K6BKD0; A0A2K6MDT5; A0A2K6Q2B5; A0A2R9CPF8; A0A2U3WAS2; A0A2U3XPQ5; A0A2Y9R2V7; A0A384BST9; A0A3Q7QRU5; A0A3Q7SQX8; A0A452RWS8; A0A4X1V0B9; A0A5E4AFY5; A0A5N4E668; A0A667HEB5; A0A671G6M8; A0A673T0V2; A0A6D2VSK7; A0A6D2WEQ2; A0A6G1BFF3; A0A6I9IA29; A0A6J1YUG6; A0A6J2CMJ0; A0A6J2LK21; A0A6P6GX89; A0A7J7WGC8; A0A7J7XTS6; A0A7J8FQY6; A0A811ZBK8; A0A8B7V7Z4; A0A8B8T0S6; A0A8C0N7M6; A0A8C5KHE0; A0A8C5V357; A0A8C6EUY0; A0A8C6RKM3; A0A8C8WVH7; A0A8C9JRV6; A0A8C9Q947; A0A8D2AN63; A0A8D2EE05; A0A8D2H908; A0A8I3S2U7; A0A8J8XE04; A0A8J8XJ71; A0A8M1M6Z7; aju:106967098; aml:100477711; cang:105517357; caty:105580103; ccan:109691946; cfa:607922; cfr:102508765; csab:103217717; D2H8G8; F7AUB4; G1PTV7; G1R662; G1SNW9; G3TAZ1; G7N8R8; H2P8F2; H2R2Y2; I3MRM5; lav:100675162; lww:102748542; M3W964; mcc:708717; mcf:102141699; mleu:105549382; mlf:102428529; mmur:105864304; myb:102246867; ngi:103744440; ocu:100351999; oro:101383024; pdic:114495167; ptr:459901; Q5U0J5; rbb:108540349; rro:104680220; S7N6N9; tmu:101356881; umr:103659802; vpc:102531048; vvp:112922611; zca:113919503"	"NCAM signaling for neurite out-growth; CREB phosphorylation; CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling; Gastrin-CREB signalling pathway via PKC and MAPK; NGF-stimulated transcription"	"IL-2 signaling pathway; EGFR1 signaling pathway; Adipogenesis; Androgen receptor signaling pathway; p38 MAPK signaling pathway; G1 to S cell cycle control; Androgen receptor signaling pathway; miRNA regulation of DNA damage response; Energy metabolism; miRNAs involved in DNA damage response; Folate-alcohol and cancer pathway hypotheses; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Follicle stimulating hormone (FSH) signaling pathway; B cell receptor signaling pathway; Interleukin-11 signaling pathway; Corticotropin-releasing hormone signaling pathway; Adipogenesis; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; ATM signaling pathway; Myometrial relaxation and contraction pathways; VEGFA-VEGFR2 signaling; Mitochondrial gene expression; p38 MAPK signaling pathway; EGF/EGFR signaling pathway; G1 to S cell cycle control; Gastrin signaling pathway; CAMKK2 pathway; Galanin receptor pathway; Neuroinflammation and glutamatergic signaling; GDNF signaling; Interferon type I signaling pathways; T-cell receptor signaling pathway; Sudden infant death syndrome (SIDS) susceptibility pathways; DNA damage response; Estrogen signaling pathway; Serotonin HTR1 group and FOS pathway; Serotonin receptor 4/6/7 and NR3C signaling; EGFR1 signaling pathway; Adipogenesis; Androgen receptor signaling pathway; p38 MAPK signaling pathway; G1 to S cell cycle control"	"49"	"0"	"259.6"	"108.8"	"285.5"	"252.6"	"282.2"	"342.9"	"236.0"	"316.5"	"210.5"	"641.7"	"1770.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H0E9"	"Bromodomain-containing protein 8 OS=Homo sapiens OX=9606 GN=BRD8 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1235"	"135.3"	"4.60"	"298.39"	"2.77"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00439"	"10902"	"ENSG00000112983"	"BRD8"	"hsa:10902; O43178; Q15355; Q58AB0; Q59GN0; Q969M9; Q9H0E9"	"HATs acetylate histones"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O60245"	"Protocadherin-7 OS=Homo sapiens OX=9606 GN=PCDH7 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1069"	"116.0"	"5.19"	""	"2.76"	""	"1"	"cell adhesion"	"plasma membrane;other membranes"	"other molecular function"	"Pf00028, Pf08266, Pf08374"	"5099"	"ENSG00000169851"	"PCDH7"	"hsa:5099; O60245; O60246; O60247; Q4W5C4"	"RHOA GTPase cycle; RHOB GTPase cycle; Platelet degranulation"	""	"3"	"0"	"15.9"	"4.8"	"12.1"	"8.2"	"10.7"	"11.3"	"13.8"	"14.9"	"13.9"	"27.3"	"83.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N6M0"	"Deubiquitinase OTUD6B OS=Homo sapiens OX=9606 GN=OTUD6B PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"293"	"33.8"	"6.05"	"380.99"	"2.76"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	""	"other molecular function"	"Pf02338"	"51633"	"ENSG00000155100"	"OTUD6B"	"A8K6I1; B4DEY0; hsa:51633; Q8N6M0; Q9NTA4; Q9Y387"	""	"Warburg effect modulated by deubiquitinating enzymes and their substrates"	"1"	"0"	"8.4"	"3.0"	"5.1"	"2.2"	"3.5"	"2.9"	"5.7"	"11.7"	"2.3"	"8.5"	"178.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y295"	"Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"367"	"40.5"	"8.90"	"319.14"	"2.75"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01926, Pf02824, Pf16897"	"4733"	"ENSG00000185721"	"DRG1"	"B2RDS8; hsa:4733; Q6FGP8; Q8WW69; Q9UGF2; Q9Y295"	""	""	"0"	"0"	"31.4"	"11.9"	"33.2"	"25.2"	"25.2"	"32.7"	"29.5"	"38.8"	"42.3"	"89.3"	"122.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q05823"	"2-5A-dependent ribonuclease OS=Homo sapiens OX=9606 GN=RNASEL PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"741"	"83.5"	"6.65"	""	"2.75"	""	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00023, Pf00069, Pf06479"	"6041"	"ENSG00000135828"	"RNASEL"	"hsa:6041; Q05823; Q5W0L2; Q6AI46"	"OAS antiviral response; Interferon alpha/beta signaling"	""	"2"	"0"	"25.4"	"11.8"	"24.5"	"21.7"	"21.4"	"25.4"	"18.1"	"28.1"	"32.2"	"114.3"	"171.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P0J0"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 OS=Homo sapiens OX=9606 GN=NDUFA13 PE=1 SV=3"	"0.000"	""	"6"	"1"	"2"	"1"	"144"	"16.7"	"8.43"	"314.73"	"2.75"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport;signal transduction;other biological processes"	"other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf06212"	"51079"	"ENSG00000186010"	"NDUFA13"	"B4DF76; hsa:51079; K7EK58; Q6PKI0; Q9H2L3; Q9P0J0; Q9Y327"	"Complex I biogenesis"	"Nucleotide-binding oligomerization domain (NOD) pathway; EGF/EGFR signaling pathway; Nonalcoholic fatty liver disease"	"5"	"0"	"139.7"	"53.9"	"99.7"	"88.4"	"115.6"	"133.1"	"93.3"	"113.1"	"108.0"	"260.1"	"473.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKX7"	"Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"468"	"50.1"	"7.06"	"357.81"	"2.74"	"1"	"1"	"transport"	"other membranes;nucleus"	""	"Pf00638, Pf08911"	"10762"	"ENSG00000093000"	"NUP50"	"B1AHA4; B2RB15; hsa:10762; O75644; Q8N6V5; Q9NPM9; Q9NPR6; Q9P1K5; Q9UKX7"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; SUMOylation of DNA replication proteins; Regulation of HSF1-mediated heat shock response; ISG15 antiviral mechanism; HCMV Early Events; HCMV Late Events; Transcriptional regulation by small RNAs; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	""	"28"	"0"	"104.4"	"67.9"	"87.3"	"63.7"	"76.8"	"75.5"	"63.3"	"85.9"	"89.4"	"127.5"	"195.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13888"	"General transcription factor IIH subunit 2 OS=Homo sapiens OX=9606 GN=GTF2H2 PE=1 SV=1"	"0.000"	""	"5"	"2"	"3"	"2"	"395"	"44.4"	"6.76"	"548.15"	"2.74"	"2"	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"nucleus"	"other molecular function"	"Pf04056, Pf07975"	"2966"	"ENSG00000145736; ENSG00000275045; ENSG00000276910"	"GTF2H2"	"hsa:2966; Q13888; Q15570; Q15571; Q9BS41"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Dual Incision in GG-NER"	"Eukaryotic transcription initiation; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"33"	"0"	"53.7"	"21.1"	"42.8"	"41.6"	"51.5"	"46.5"	"33.9"	"68.5"	"99.2"	"242.4"	"316.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NZR1"	"Tropomodulin-2 OS=Homo sapiens OX=9606 GN=TMOD2 PE=1 SV=1"	"0.001"	""	"2"	"1"	"2"	"1"	"351"	"39.6"	"5.27"	"286.52"	"2.74"	"1"	"1"	"cell-cell signaling;cell organization and biogenesis;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf03250"	"29767"	"ENSG00000128872"	"TMOD2"	"B4DEW6; hsa:29767; Q9NZR1"	"Striated Muscle Contraction"	""	"1"	"0"	"106.4"	"41.6"	"75.1"	"75.2"	"75.3"	"94.4"	"70.5"	"104.3"	"68.1"	"195.7"	"392.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94887"	"FERM, ARHGEF and pleckstrin domain-containing protein 2 OS=Homo sapiens OX=9606 GN=FARP2 PE=1 SV=3"	"0.001"	""	"1"	"1"	"2"	"1"	"1054"	"119.8"	"8.79"	"272.36"	"2.74"	"1"	"1"	"cell adhesion;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;cytoskeletal activity"	"Pf00169, Pf00373, Pf00621, Pf08736, Pf09379, Pf09380"	"9855"	"ENSG00000006607"	"FARP2"	"B7Z6J8; F5GZ84; hsa:9855; O94887; Q53QM5; Q8WU27; Q9UFE7"	"RAC1 GTPase cycle; SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"	"2q37 copy number variation syndrome; TAR syndrome"	"4"	"0"	"139.6"	"50.4"	"126.0"	"115.6"	"109.7"	"130.4"	"96.0"	"134.5"	"112.9"	"353.1"	"612.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99848"	"Probable rRNA-processing protein EBP2 OS=Homo sapiens OX=9606 GN=EBNA1BP2 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"306"	"34.8"	"10.10"	"358.11"	"2.74"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf05890"	"10969"	"ENSG00000117395"	"EBNA1BP2"	"hsa:10969; Q96A66; Q99848"	"Major pathway of rRNA processing in the nucleolus and cytosol"	""	"1"	"0"	"124.0"	"62.3"	"93.7"	"67.7"	"92.8"	"92.5"	"84.0"	"104.2"	"107.5"	"174.4"	"240.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61970"	"Nuclear transport factor 2 OS=Homo sapiens OX=9606 GN=NUTF2 PE=1 SV=1"	"0.000"	""	"11"	"2"	"3"	"2"	"127"	"14.5"	"5.38"	"534.09"	"2.73"	"2"	"1"	"transport;other biological processes"	"other membranes;cytosol;nucleus"	"other molecular function"	"Pf02136"	"10204"	"ENSG00000102898"	"NUTF2"	"B2R4G7; hsa:10204; P13662; P61970; Q6IB67"	""	""	"0"	"0"	"419.7"	"120.8"	"206.1"	"131.2"	"233.8"	"191.2"	"237.2"	"262.7"	"354.0"	"504.2"	"1038.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P29144"	"Tripeptidyl-peptidase 2 OS=Homo sapiens OX=9606 GN=TPP2 PE=1 SV=4"	"0.001"	""	"1"	"1"	"2"	"1"	"1249"	"138.3"	"6.32"	"260.96"	"2.73"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00082, Pf12580"	"7174"	"ENSG00000134900"	"TPP2"	"hsa:7174; P29144; Q5VZU8"	"Antigen processing: Ubiquitination & Proteasome degradation"	""	"1"	"0"	"11.7"	"7.1"	"9.7"	"6.5"	"12.4"	"10.5"	"8.6"	"7.5"	"11.1"	"10.8"	"21.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75530"	"Polycomb protein EED OS=Homo sapiens OX=9606 GN=EED PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"441"	"50.2"	"7.03"	"302.20"	"2.73"	"1"	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00400"	"8726"	"ENSG00000074266"	"EED"	"A8K7V5; hsa:8726; O00149; O75530; Q6NTH2; Q7LDA5; Q7LDG8; Q86VV2; Q9UNY7"	"Transcriptional Regulation by E2F6; HCMV Early Events; Oxidative Stress Induced Senescence; Regulation of PTEN gene transcription; Activation of anterior HOX genes in hindbrain development during early embryogenesis; PKMTs methylate histone lysines; PRC2 methylates histones and DNA; Defective pyroptosis"	"Histone modifications; Interactome of polycomb repressive complex 2 (PRC2) ; Tumor suppressor activity of SMARCB1; Epithelial to mesenchymal transition in colorectal cancer; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; Pleural mesothelioma; 5q35 copy number variation"	"15"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8TER5"	"Rho guanine nucleotide exchange factor 40 OS=Homo sapiens OX=9606 GN=ARHGEF40 PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"1519"	"164.6"	"6.15"	""	"2.72"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"enzyme regulator activity"	"Pf00621"	"55701"	"ENSG00000165801"	"ARHGEF40"	"A5PL07; hsa:55701; Q8TER5; Q9BWP5; Q9H7L6; Q9NTF9; Q9NW24"	"G alpha (12/13) signalling events; RHOC GTPase cycle; RHOA GTPase cycle; NRAGE signals death through JNK"	""	"4"	"0"	"105.1"	"42.2"	"90.4"	"77.8"	"81.0"	"96.1"	"71.7"	"112.7"	"99.7"	"116.2"	"234.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11413"	"Glucose-6-phosphate 1-dehydrogenase OS=Homo sapiens OX=9606 GN=G6PD PE=1 SV=4"	"0.000"	""	"2"	"1"	"2"	"1"	"515"	"59.2"	"6.84"	"315.56"	"2.72"	"1"	"1"	"other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00479, Pf02781"	"2539"	"ENSG00000160211"	"G6PD"	"D3DWX9; hsa:2539; P11413; Q16000; Q16765; Q8IU70; Q8IU88; Q8IUA6; Q96PQ2"	"TP53 Regulates Metabolic Genes; NFE2L2 regulates pentose phosphate pathway genes; Pentose phosphate pathway"	"Glutathione metabolism; Pentose phosphate metabolism; Cori cycle; Vitamin D receptor pathway; Nuclear receptors meta-pathway; NRF2 pathway; ATM signaling in development and disease ; Metabolic reprogramming in colon cancer; Vitamin D-sensitive calcium signaling in depression; Pentose phosphate pathway in senescent cells; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Glycolysis in senescence; Sulfation biotransformation reaction"	"16"	"0"	"83.9"	"35.5"	"84.1"	"59.7"	"85.0"	"77.0"	"63.6"	"82.9"	"58.9"	"115.9"	"175.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H9T3"	"Elongator complex protein 3 OS=Homo sapiens OX=9606 GN=ELP3 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"547"	"62.2"	"8.88"	"312.37"	"2.71"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00583, Pf04055, Pf16199"	"55140"	"ENSG00000134014"	"ELP3"	"B4DE19; B4DIG1; E2QRI5; hsa:55140; Q53G84; Q6AWB0; Q9BVF7; Q9H9T3; Q9NVZ1"	"HATs acetylate histones"	"Ethanol effects on histone modifications"	"2"	"0"	"67.0"	"31.0"	"58.8"	"59.8"	"54.9"	"72.8"	"52.1"	"60.5"	"46.8"	"79.2"	"165.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P31040"	"Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"664"	"72.6"	"7.39"	"339.21"	"2.71"	"1"	"1"	"other metabolic processes;developmental processes"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf00890, Pf02910"	"6389"	"ENSG00000073578"	"SDHA"	"A8K5J6; B4DJ60; E9PBJ5; hsa:6389; P31040; Q16395; Q59GW8; Q8IW48; Q9UMY5"	"Respiratory electron transport; Citric acid cycle (TCA cycle)"	"Electron transport chain: OXPHOS system in mitochondria; TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Nonalcoholic fatty liver disease; Mitochondrial complex II assembly; Arsenic metabolism and reactive oxygen species generation; TCA cycle (aka Krebs or citric acid cycle)"	"9"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H9A5"	"CCR4-NOT transcription complex subunit 10 OS=Homo sapiens OX=9606 GN=CNOT10 PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"744"	"82.3"	"7.78"	""	"2.71"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	""	"25904"	"ENSG00000182973"	"CNOT10"	"B7Z7L1; F8WAF2; hsa:25904; Q9BU30; Q9H5J7; Q9H8X1; Q9H9A5; Q9H9W0; Q9HAH3; Q9UFJ2"	"Deadenylation of mRNA; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"	"Ciliary landscape"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NRY2"	"SOSS complex subunit C OS=Homo sapiens OX=9606 GN=INIP PE=1 SV=1"	"0.000"	""	"9"	"1"	"2"	"1"	"104"	"11.4"	"9.25"	"369.47"	"2.71"	"1"	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	""	"Pf15925"	"58493"	"ENSG00000148153"	"INIP"	"hsa:58493; Q5VWJ7; Q96E04; Q9NRY2; Q9P090"	""	""	"0"	"0"	"106.9"	"45.8"	"103.3"	"79.4"	"104.1"	"105.8"	"77.4"	"114.0"	"96.1"	"192.0"	"409.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y3D3"	"28S ribosomal protein S16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS16 PE=1 SV=1"	""	""	"9"	"1"	"1"	"1"	"137"	"15.3"	"9.50"	""	"2.71"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;cytosol;mitochondrion;translational apparatus"	"other molecular function"	"Pf00886"	"51021"	"ENSG00000182180"	"MRPS16"	"B4E032; hsa:51021; Q96Q60; Q9Y3D3"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"21.4"	"10.5"	"12.7"	"13.2"	"15.1"	"13.1"	"9.8"	"18.3"	"12.8"	"26.3"	"34.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HAU5"	"Regulator of nonsense transcripts 2 OS=Homo sapiens OX=9606 GN=UPF2 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1272"	"147.7"	"5.69"	"363.58"	"2.70"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02854, Pf04050"	"26019"	"ENSG00000151461"	"UPF2"	"A6NLJ5; D3DRS0; hsa:26019; Q14BM1; Q5W0J4; Q8N8U1; Q9H1J2; Q9HAU5; Q9NWL1; Q9P2D9; Q9Y4M9"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	""	"2"	"0"	"33.1"	"13.3"	"31.6"	"20.1"	"23.9"	"31.0"	"24.9"	"32.5"	"30.7"	"56.1"	"130.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14739"	"Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"615"	"70.7"	"9.36"	"295.49"	"2.70"	"1"	"1"	"other metabolic processes;other biological processes"	"other membranes;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01222, Pf09465"	"3930"	"ENSG00000143815"	"LBR"	"B2R5P3; hsa:3930; Q14739; Q14740; Q53GU7; Q59FE6"	"Initiation of Nuclear Envelope (NE) Reformation; RHOG GTPase cycle; RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOD GTPase cycle; Regulation of MECP2 expression and activity; Cholesterol biosynthesis"	"Gastric cancer network 2; ATM signaling in development and disease ; Envelope proteins and their potential roles in EDMD physiopathology; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Cholesterol biosynthesis with skeletal dysplasias; Cholesterol synthesis disorders; Cholesterol metabolism; Enterocyte cholesterol metabolism"	"19"	"0"	"123.4"	"42.4"	"87.8"	"69.1"	"83.8"	"92.0"	"87.2"	"135.2"	"112.8"	"165.0"	"339.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25325"	"3-mercaptopyruvate sulfurtransferase OS=Homo sapiens OX=9606 GN=MPST PE=1 SV=3"	"0.000"	""	"6"	"2"	"4"	"1"	"297"	"33.2"	"6.60"	"824.11"	"2.70"	"2"	"1"	"other metabolic processes;developmental processes;other biological processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00581"	"4357"	"ENSG00000128309"	"MPST"	"A8MZ34; B3KP52; hsa:4357; J3KPV7; O75750; P25325; Q6FHN9"	"Degradation of cysteine and homocysteine"	"Trans-sulfuration pathway; Amino acid metabolism"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q6DD87"	"Zinc finger protein 787 OS=Homo sapiens OX=9606 GN=ZNF787 PE=1 SV=4"	""	""	"5"	"1"	"1"	"1"	"382"	"40.4"	"7.96"	""	"2.69"	""	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00096, Pf13912"	"126208"	"ENSG00000142409"	"ZNF787"	"A0A087WUD1; hsa:126208; O00455; Q6DD87"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P00387"	"NADH-cytochrome b5 reductase 3 OS=Homo sapiens OX=9606 GN=CYB5R3 PE=1 SV=3"	"0.000"	""	"4"	"1"	"2"	"1"	"301"	"34.2"	"7.59"	"359.65"	"2.69"	"1"	"1"	"other metabolic processes;other biological processes"	"non-structural extracellular;other membranes;cytosol;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00175, Pf00970"	"1727"	"ENSG00000100243"	"CYB5R3"	"B1AHF2; B7Z7L3; hsa:1727; O75675; P00387; Q8TDL8; Q8WTS8; Q9UEN4; Q9UEN5; Q9UL55; Q9UL56"	"Phase I - Functionalization of compounds; Neutrophil degranulation; Vitamin C (ascorbate) metabolism"	"Oxidation by cytochrome P450"	"4"	"0"	"30.3"	"10.6"	"21.0"	"20.9"	"30.2"	"23.7"	"21.7"	"30.7"	"27.1"	"55.7"	"100.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P58397"	"A disintegrin and metalloproteinase with thrombospondin motifs 12 OS=Homo sapiens OX=9606 GN=ADAMTS12 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1594"	"177.6"	"7.87"	""	"2.69"	""	"1"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"non-structural extracellular;extracellular matrix"	"other molecular function"	"Pf00090, Pf01421, Pf01562, Pf05986, Pf17771, Pf19030, Pf19236"	"81792"	"ENSG00000151388"	"ADAMTS12"	"A2RRN9; A5D6V6; hsa:81792; P58397; Q6UWL3"	"Defective B3GALTL causes PpS; O-glycosylation of TSR domain-containing proteins"	""	"2"	"0"	"82.4"	"24.7"	"45.0"	"33.7"	"42.4"	"30.3"	"34.5"	"44.3"	"51.2"	"194.5"	"363.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NWU2"	"Glucose-induced degradation protein 8 homolog OS=Homo sapiens OX=9606 GN=GID8 PE=1 SV=1"	"0.001"	""	"5"	"1"	"2"	"1"	"228"	"26.7"	"4.97"	"253.64"	"2.69"	"1"	"1"	"cell-cell signaling;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf08513, Pf10607"	"54994"	"ENSG00000101193"	"GID8"	"E1P5I3; hsa:54994; Q8N5M5; Q9NWU2"	""	"Ciliary landscape"	"1"	"0"	"14.1"	"5.1"	"14.7"	"8.2"	"9.1"	"14.7"	"12.3"	"13.5"	"13.2"	"33.9"	"52.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6A4"	"Cilia- and flagella-associated protein 20 OS=Homo sapiens OX=9606 GN=CFAP20 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"193"	"22.8"	"9.76"	"335.02"	"2.69"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	""	"Pf05018"	"29105"	"ENSG00000070761"	"CFAP20"	"hsa:29105; Q9Y6A4"	""	""	"0"	"0"	"170.1"	"72.9"	"127.7"	"102.8"	"126.5"	"145.8"	"141.0"	"183.0"	"158.2"	"290.6"	"380.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UPN6"	"SR-related and CTD-associated factor 8 OS=Homo sapiens OX=9606 GN=SCAF8 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1271"	"140.4"	"8.29"	"395.12"	"2.69"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf04818"	"22828"	"ENSG00000213079"	"SCAF8"	"B7Z888; hsa:22828; Q5TBU6; Q6NSK3; Q9BQN8; Q9BX43; Q9UPN6"	""	""	"0"	"0"	"61.7"	"30.5"	"54.5"	"38.3"	"42.3"	"53.8"	"44.9"	"55.2"	"52.9"	"99.6"	"173.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H0U9"	"Testis-specific Y-encoded-like protein 1 OS=Homo sapiens OX=9606 GN=TSPYL1 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"437"	"49.2"	"5.45"	"326.17"	"2.68"	"1"	"1"	"cell organization and biogenesis"	"nucleus;other cell component"	"other molecular function"	"Pf00956"	"7259"	"ENSG00000189241"	"TSPYL1"	"hsa:7259; O75885; Q5TFE6; Q9H0U9"	""	"Sudden infant death syndrome (SIDS) susceptibility pathways"	"1"	"0"	"15.0"	"3.0"	"16.0"	"12.5"	"11.1"	"18.5"	"10.7"	"14.1"	"7.1"	"14.1"	"26.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H583"	"HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"2144"	"242.2"	"6.54"	"357.75"	"2.68"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity"	"Pf08146, Pf12397"	"55127"	"ENSG00000119285"	"HEATR1"	"hsa:55127; Q5T3Q8; Q6P197; Q9H583; Q9NW23"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TBB5"	"Kelch domain-containing protein 4 OS=Homo sapiens OX=9606 GN=KLHDC4 PE=1 SV=1"	"0.001"	""	"2"	"1"	"2"	"1"	"520"	"57.9"	"5.72"	"291.13"	"2.68"	"1"	"1"	""	""	""	"Pf07646, Pf13418, Pf13854, Pf13964"	"54758"	"ENSG00000104731"	"KLHDC4"	"D3DUN3; D3DUN4; D3DUN5; hsa:54758; Q8TBB5; Q96F29; Q9BVN3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07947"	"Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"543"	"60.8"	"6.74"	"371.33"	"2.68"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf00017, Pf00018, Pf07714"	"7525"	"ENSG00000176105"	"YES1"	"A6NLB3; D3DUH1; hsa:7525; P07947"	"FCGR activation; FCGR3A-mediated IL10 synthesis; FCGR3A-mediated phagocytosis; Regulation of signaling by CBL; EPHB-mediated forward signaling; Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants; Regulation of KIT signaling; Signaling by ERBB2; EPH-ephrin mediated repulsion of cells; EPHA-mediated growth cone collapse; Signaling by CSF1 (M-CSF) in myeloid cells; RUNX2 regulates osteoblast differentiation; CD28 co-stimulation; PECAM1 interactions; CTLA4 inhibitory signaling"	"Thymic stromal lymphopoietin (TSLP) signaling pathway; Interleukin-11 signaling pathway; NRF2-ARE regulation; Gastrin signaling pathway; GDNF signaling"	"22"	"0"	"272.5"	"88.8"	"158.2"	"133.5"	"169.6"	"185.8"	"152.0"	"178.0"	"191.3"	"277.3"	"561.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UBH6"	"Xenotropic and polytropic retrovirus receptor 1 OS=Homo sapiens OX=9606 GN=XPR1 PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"696"	"81.5"	"8.44"	""	"2.68"	""	"1"	"stress response;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"transporter activity;other molecular function"	"Pf03105, Pf03124"	"9213"	"ENSG00000143324"	"XPR1"	"hsa:9213; O95719; Q7L8K9; Q8IW20; Q9NT19; Q9UBH6; Q9UFB9"	""	""	"0"	"0"	"130.2"	"62.9"	"111.7"	"91.4"	"97.6"	"119.1"	"94.5"	"124.1"	"107.7"	"228.8"	"388.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6M4"	"Casein kinase I isoform gamma-3 OS=Homo sapiens OX=9606 GN=CSNK1G3 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"447"	"51.4"	"9.22"	"301.42"	"2.67"	"1"	"1"	"cell-cell signaling;protein metabolism;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf12605"	"1456"	"ENSG00000151292"	"CSNK1G3"	"A8K040; B4DSH2; B7Z9Q4; E7EVD0; hsa:1456; Q86WZ7; Q9Y6M3; Q9Y6M4"	""	"Hedgehog signaling pathway"	"1"	"0"	"177.2"	"64.3"	"156.2"	"145.7"	"143.5"	"169.5"	"134.4"	"183.8"	"148.0"	"462.5"	"977.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49790"	"Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1475"	"153.8"	"8.73"	"307.70"	"2.67"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00641, Pf08604, Pf10599"	"9972"	"ENSG00000124789"	"NUP153"	"B4DIK2; E7EPX5; F6QR24; hsa:9972; P49790; Q4LE47; Q5T9I7; Q7Z743"	"Nuclear import of Rev protein; HCMV Late Events; HCMV Early Events; Transcriptional regulation by small RNAs; SUMOylation of DNA replication proteins; ISG15 antiviral mechanism; Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	""	"28"	"0"	"157.8"	"64.3"	"125.7"	"113.7"	"127.8"	"148.3"	"105.6"	"141.9"	"110.6"	"282.9"	"545.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N1I0"	"Dedicator of cytokinesis protein 4 OS=Homo sapiens OX=9606 GN=DOCK4 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1966"	"225.1"	"7.65"	"301.95"	"2.67"	"1"	"1"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf06920, Pf07653, Pf14429, Pf16172, Pf20421, Pf20422"	"9732"	"ENSG00000128512"	"DOCK4"	"hsa:9732; O14584; O94824; Q8N1I0; Q8NB45"	"RAC1 GTPase cycle; Factors involved in megakaryocyte development and platelet production; RHOG GTPase cycle; RAC2 GTPase cycle"	""	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UIG0"	"Tyrosine-protein kinase BAZ1B OS=Homo sapiens OX=9606 GN=BAZ1B PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1483"	"170.8"	"8.48"	"300.01"	"2.67"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00439, Pf00628, Pf10537, Pf15612, Pf15613"	"9031"	"ENSG00000009954"	"BAZ1B"	"B9EGK3; D3DXE9; hsa:9031; O95039; O95247; O95277; Q6P1K4; Q86UJ6; Q9UIG0"	"B-WICH complex positively regulates rRNA expression; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"	"IL-18 signaling pathway; 7q11.23 copy number variation syndrome; 10q11.21q11.23 copy number variation syndrome"	"5"	"0"	"14.4"	"5.1"	"10.2"	"11.2"	"7.5"	"12.0"	"11.2"	"11.8"	"13.2"	"24.9"	"56.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q969S3"	"Zinc finger protein 622 OS=Homo sapiens OX=9606 GN=ZNF622 PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"477"	"54.2"	"6.15"	""	"2.67"	""	"1"	"signal transduction;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf12171, Pf12756"	"90441"	"ENSG00000173545"	"ZNF622"	"hsa:90441; Q969S3"	""	""	"0"	"0"	"18.5"	"6.0"	"13.1"	"20.6"	"13.9"	"21.2"	"16.7"	"20.1"	"15.9"	"28.0"	"25.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O75175"	"CCR4-NOT transcription complex subunit 3 OS=Homo sapiens OX=9606 GN=CNOT3 PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"753"	"81.8"	"6.20"	""	"2.66"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf04065, Pf04153"	"4849"	"ENSG00000088038; ENSG00000273943; ENSG00000274176; ENSG00000274616; ENSG00000274941; ENSG00000275979; ENSG00000276082; ENSG00000277114; ENSG00000277600; ENSG00000277615"	"CNOT3"	"hsa:4849; O75175; Q9NZN7; Q9UF76"	"Deadenylation of mRNA; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H9B1"	"Histone-lysine N-methyltransferase EHMT1 OS=Homo sapiens OX=9606 GN=EHMT1 PE=1 SV=4"	"0.000"	""	"1"	"1"	"2"	"1"	"1298"	"141.4"	"5.76"	"312.95"	"2.66"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00856, Pf05033, Pf12796"	"79813"	"ENSG00000181090"	"EHMT1"	"B1AQ58; B1AQ59; hsa:79813; Q86X08; Q8TCN7; Q96F53; Q96JF1; Q96KH4; Q9H9B1"	"PKMTs methylate histone lysines; Senescence-Associated Secretory Phenotype (SASP); Regulation of TP53 Activity through Methylation; Transcriptional Regulation by E2F6; Transcriptional Regulation by VENTX"	"Histone modifications; MTHFR deficiency; Kleefstra syndrome"	"8"	"0"	"11.7"	"6.1"	"15.1"	"9.3"	"13.6"	"13.5"	"8.8"	"14.0"	"9.5"	"17.7"	"29.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96F85"	"CB1 cannabinoid receptor-interacting protein 1 OS=Homo sapiens OX=9606 GN=CNRIP1 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"164"	"18.6"	"7.94"	"338.14"	"2.66"	"1"	"1"	"other biological processes"	"plasma membrane;other membranes;other cell component"	"signal transduction activity or receptor binding"	"Pf15043"	"25927"	"ENSG00000119865"	"CNRIP1"	"B2R4D0; hsa:25927; Q49AN4; Q96F85; Q9UFZ0"	""	""	"0"	"0"	"29.3"	"11.6"	"27.1"	"22.5"	"28.5"	"35.2"	"37.3"	"167.1"	"314.4"	"898.3"	"1381.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IXQ4"	"GPALPP motifs-containing protein 1 OS=Homo sapiens OX=9606 GN=GPALPP1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"340"	"38.1"	"5.41"	"343.37"	"2.66"	"1"	"1"	""	""	""	"Pf12572"	"55425"	"ENSG00000133114"	"GPALPP1"	"A8K8X8; hsa:55425; Q05BX8; Q05D87; Q5T3Z3; Q5T3Z5; Q8IXQ4; Q9C0F9; Q9H2R0; Q9P0W6"	""	""	"0"	"0"	"58.9"	"25.7"	"60.7"	"78.4"	"81.7"	"88.3"	"63.5"	"78.4"	"50.2"	"101.9"	"170.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BPX5"	"Actin-related protein 2/3 complex subunit 5-like protein OS=Homo sapiens OX=9606 GN=ARPC5L PE=1 SV=1"	"0.000"	""	"8"	"1"	"2"	"1"	"153"	"16.9"	"6.60"	"402.52"	"2.66"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf04699"	"81873"	"ENSG00000136950"	"ARPC5L"	"hsa:81873; Q7Z523; Q9BPX5"	""	"Pathogenic Escherichia coli infection; VEGFA-VEGFR2 signaling"	"2"	"0"	"33.6"	"15.3"	"26.3"	"23.9"	"27.8"	"28.5"	"27.2"	"30.0"	"31.7"	"168.4"	"434.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96DE0"	"U8 snoRNA-decapping enzyme OS=Homo sapiens OX=9606 GN=NUDT16 PE=1 SV=2"	"0.000"	""	"8"	"1"	"2"	"1"	"195"	"21.3"	"6.89"	"320.20"	"2.65"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00293"	"131870"	"ENSG00000198585"	"NUDT16"	"B4E3B4; E9PED4; F5GYJ1; hsa:131870; Q96DE0; Q96N82"	"Phosphate bond hydrolysis by NUDT proteins"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TBF4"	"Zinc finger CCHC-type and RNA-binding motif-containing protein 1 OS=Homo sapiens OX=9606 GN=ZCRB1 PE=1 SV=2"	"0.001"	""	"5"	"1"	"2"	"1"	"217"	"24.6"	"8.53"	"257.59"	"2.65"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00076, Pf00098"	"85437"	"ENSG00000139168"	"ZCRB1"	"hsa:85437; Q6PJX0; Q8TBF4; Q96TA6"	"mRNA Splicing - Minor Pathway; Replication of the SARS-CoV-1 genome; Replication of the SARS-CoV-2 genome"	""	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q07864"	"DNA polymerase epsilon catalytic subunit A OS=Homo sapiens OX=9606 GN=POLE PE=1 SV=5"	"0.000"	""	"0"	"1"	"2"	"1"	"2286"	"261.4"	"6.39"	"335.65"	"2.65"	"1"	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;developmental processes"	"plasma membrane;other membranes;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00136, Pf03104, Pf08490"	"5426"	"ENSG00000177084"	"POLE"	"hsa:5426; Q07864; Q13533; Q86VH9"	"Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Activation of the pre-replicative complex; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; DNA replication initiation; Gap-filling DNA repair synthesis and ligation in GG-NER"	"Retinoblastoma gene in cancer; Pyrimidine metabolism; G1 to S cell cycle control; DNA replication; Base excision repair; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"19"	"0"	"38.5"	"20.3"	"34.4"	"27.5"	"33.4"	"30.2"	"29.0"	"35.8"	"37.7"	"64.1"	"122.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9C0C2"	"182 kDa tankyrase-1-binding protein OS=Homo sapiens OX=9606 GN=TNKS1BP1 PE=1 SV=4"	"0.000"	""	"1"	"2"	"3"	"2"	"1729"	"181.7"	"4.86"	"529.92"	"2.64"	"2"	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf15327"	"85456"	"ENSG00000149115"	"TNKS1BP1"	"A7E2F8; hsa:85456; Q6PJ35; Q6ZV74; Q9C0C2"	"Deadenylation of mRNA; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"	"Ciliary landscape"	"3"	"0"	"8.9"	"5.1"	"10.9"	"9.2"	"8.2"	"6.4"	"7.4"	"11.4"	"8.4"	"17.8"	"27.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TEM1"	"Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1887"	"205.0"	"6.81"	"305.14"	"2.64"	"1"	"1"	"transport"	"other membranes;ER/Golgi;nucleus"	""	"Pf02368"	"23225"	"ENSG00000132182"	"NUP210"	"A6NN56; hsa:23225; O94980; Q6NXG6; Q8NBJ1; Q8TEM1; Q9H6C8; Q9UFP3"	"SUMOylation of DNA damage response and repair proteins; Vpr-mediated nuclear import of PICs; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Regulation of HSF1-mediated heat shock response; SUMOylation of chromatin organization proteins; HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; snRNP Assembly; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus"	""	"28"	"0"	"16.3"	"6.8"	"16.4"	"10.8"	"13.5"	"14.4"	"10.4"	"10.2"	"12.6"	"21.7"	"52.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30044"	"Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4"	"0.000"	""	"4"	"1"	"2"	"1"	"214"	"22.1"	"8.70"	"366.46"	"2.64"	"1"	"1"	"other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf08534"	"25824"	"ENSG00000126432"	"PRDX5"	"A6NC19; A6NG06; B7ZLJ4; B7ZVW3; hsa:25824; P30044; Q14CK0; Q6IAF2; Q9UBU5; Q9UJU4; Q9UKX4"	""	"Selenium micronutrient network"	"1"	"0"	"164.0"	"61.8"	"115.3"	"79.9"	"127.2"	"119.2"	"109.3"	"130.5"	"125.0"	"192.8"	"368.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P17096"	"High mobility group protein HMG-I/HMG-Y OS=Homo sapiens OX=9606 GN=HMGA1 PE=1 SV=3"	"0.000"	""	"23"	"2"	"3"	"2"	"107"	"11.7"	"10.32"	"967.04"	"2.64"	"2"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	""	"3159"	"ENSG00000137309"	"HMGA1"	"hsa:3159; P10910; P17096; Q5T6U9; Q9UKB0"	"Vpr-mediated nuclear import of PICs; 2-LTR circle formation; Integration of viral DNA into host genomic DNA; Autointegration results in viral DNA circles; APOBEC3G mediated resistance to HIV-1 infection; Formation of Senescence-Associated Heterochromatin Foci (SAHF)"	"Adipogenesis; Pre-implantation embryo; Male infertility; 7q11.23 copy number variation syndrome; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Orexin receptor pathway"	"13"	"0"	"204.2"	"88.1"	"187.4"	"176.6"	"183.0"	"222.8"	"145.6"	"233.1"	"177.5"	"495.7"	"1148.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q2KHT3"	"Protein CLEC16A OS=Homo sapiens OX=9606 GN=CLEC16A PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1053"	"117.6"	"5.86"	""	"2.62"	""	"1"	"other metabolic processes;stress response;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf09758, Pf19439"	"23274"	"ENSG00000038532"	"CLEC16A"	"hsa:23274; O15058; Q2KHT3; Q6ZTB2"	""	"Vitamin D receptor pathway"	"1"	"0"	"109.3"	"49.1"	"130.8"	"132.6"	"134.6"	"142.9"	"122.9"	"160.0"	"107.2"	"208.4"	"336.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14241"	"Elongin-A OS=Homo sapiens OX=9606 GN=ELOA PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"798"	"89.9"	"9.57"	"1428.11"	"2.61"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf06881, Pf08711"	"6924"	"ENSG00000011007"	"ELOA"	"B2R7Q8; hsa:6924; Q14241; Q8IXH1"	"Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes"	"VEGFA-VEGFR2 signaling; 10q11.21q11.23 copy number variation syndrome"	"13"	"0"	"103.3"	"44.3"	"82.6"	"62.6"	"77.2"	"96.5"	"95.1"	"162.9"	"207.1"	"519.2"	"1074.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H3H9"	"Transcription elongation factor A protein-like 2 OS=Homo sapiens OX=9606 GN=TCEAL2 PE=2 SV=1"	"0.001"	""	"4"	"1"	"2"	"1"	"227"	"25.8"	"5.94"	"252.33"	"2.61"	"1"	"1"	""	"nucleus"	""	"Pf04538"	"140597"	"ENSG00000184905"	"TCEAL2"	"B2R5C7; hsa:140597; Q9H3H9"	""	""	"0"	"0"	"142.7"	"77.7"	"161.9"	"140.4"	"148.8"	"195.3"	"139.7"	"174.4"	"128.7"	"239.7"	"308.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6IQ49"	"Replication stress response regulator SDE2 OS=Homo sapiens OX=9606 GN=SDE2 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"451"	"49.7"	"6.05"	"322.27"	"2.61"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity"	"Pf13019, Pf13297"	"163859"	"ENSG00000143751"	"SDE2"	"A8K4P3; hsa:163859; Q5TD36; Q6IQ49; Q6ZS26; Q8NAG7"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"82.7"	"33.3"	"72.3"	"75.5"	"87.6"	"95.2"	"67.6"	"108.7"	"75.1"	"122.1"	"191.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H7N4"	"Splicing factor, arginine/serine-rich 19 OS=Homo sapiens OX=9606 GN=SCAF1 PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"1312"	"139.2"	"9.25"	""	"2.61"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	""	"58506"	"ENSG00000126461"	"SCAF1"	"hsa:58506; Q7Z5V7; Q8WVA1; Q9H7N4; Q9NR59"	""	""	"0"	"0"	"42.2"	"10.7"	"15.7"	"14.5"	"21.6"	"17.3"	"23.7"	"26.3"	"17.5"	"33.6"	"52.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P158"	"Putative ATP-dependent RNA helicase DHX57 OS=Homo sapiens OX=9606 GN=DHX57 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1386"	"155.5"	"7.71"	"379.60"	"2.61"	"1"	"1"	""	""	"other molecular function"	"Pf00270, Pf00271, Pf04408, Pf05773, Pf07717, Pf18044"	"90957"	"ENSG00000163214"	"DHX57"	"A2RRC7; hsa:90957; Q53SI4; Q6P158; Q6P9G1; Q7Z6H3; Q8NG17; Q96M33"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q67FW5"	"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 OS=Homo sapiens OX=9606 GN=B3GNTL1 PE=2 SV=2"	"0.001"	""	"3"	"1"	"2"	"1"	"361"	"40.7"	"7.40"	"239.36"	"2.61"	"1"	"1"	""	""	"other molecular function"	"Pf00535"	"146712"	"ENSG00000175711; ENSG00000277033"	"B3GNTL1"	"hsa:146712; Q67FW5; Q6GV30; Q8WUT3"	"O-linked glycosylation of mucins"	""	"1"	"0"	"0.0"	"0.0"	"0.0"	"3.0"	"0.0"	"0.0"	"8.4"	"18.0"	"29.2"	"84.0"	"65.6"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92882"	"Osteoclast-stimulating factor 1 OS=Homo sapiens OX=9606 GN=OSTF1 PE=1 SV=2"	"0.000"	""	"6"	"1"	"2"	"1"	"214"	"23.8"	"5.68"	"321.02"	"2.61"	"1"	"1"	"signal transduction;other biological processes"	"other cell component"	"other molecular function"	"Pf00018, Pf12796"	"26578"	"ENSG00000134996"	"OSTF1"	"hsa:26578; Q5W126; Q92882; Q96IJ4"	"Neutrophil degranulation"	""	"1"	"0"	"18.9"	"7.7"	"19.7"	"15.0"	"15.6"	"18.4"	"21.8"	"34.3"	"27.6"	"22.3"	"36.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H9J2"	"39S ribosomal protein L44, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL44 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"332"	"37.5"	"8.40"	"279.92"	"2.61"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"plasma membrane;other membranes;mitochondrion;translational apparatus;nucleus"	"nucleic acid binding activity;other molecular function"	""	"65080"	"ENSG00000135900"	"MRPL44"	"hsa:65080; Q53S16; Q6IA62; Q9H821; Q9H9J2"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"16.3"	"5.1"	"11.4"	"8.9"	"10.9"	"13.2"	"8.9"	"18.0"	"16.0"	"35.3"	"51.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46937"	"Transcriptional coactivator YAP1 OS=Homo sapiens OX=9606 GN=YAP1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"504"	"54.4"	"5.17"	"316.20"	"2.60"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00397"	"10413"	"ENSG00000137693"	"YAP1"	"B4DTY1; B7ZA01; E3WEB5; E3WEB6; E9PRV2; F5H202; hsa:10413; K0KQ18; K0KYZ8; K0L195; K0L1G3; P46937; Q7Z574; Q8IUY9"	"RUNX2 regulates osteoblast differentiation; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Formation of axial mesoderm; Nuclear signaling by ERBB4; Signaling by Hippo; YAP1- and WWTR1 (TAZ)-stimulated gene expression; EGR2 and SOX10-mediated initiation of Schwann cell myelination; RUNX3 regulates YAP1-mediated transcription"	"Mesodermal commitment pathway; Mesodermal commitment pathway; RAC1/PAK1/p38/MMP2 pathway; miR-509-3p alteration of YAP1/ECM axis; Ciliary landscape; Leukocyte-intrinsic Hippo pathway functions; Netrin-UNC5B signaling pathway; Galanin receptor pathway; Pleural mesothelioma"	"17"	"0"	"122.6"	"50.8"	"127.3"	"104.1"	"122.6"	"140.6"	"99.5"	"147.5"	"102.9"	"191.6"	"241.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UL51"	"Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 OS=Homo sapiens OX=9606 GN=HCN2 PE=1 SV=3"	""	""	"4"	"1"	"1"	"1"	"889"	"96.9"	"8.97"	""	"2.60"	""	"1"	"cell-cell signaling;transport;other biological processes"	"plasma membrane;other membranes;other cell component"	"transporter activity;other molecular function"	"Pf00027, Pf00520, Pf08412"	"610"	"ENSG00000099822"	"HCN2"	"hsa:610; O60742; O60743; O75267; Q9UBS2; Q9UL51"	"HCN channels"	"Genes targeted by miRNAs in adipocytes"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5EBL8"	"PDZ domain-containing protein 11 OS=Homo sapiens OX=9606 GN=PDZD11 PE=1 SV=2"	"0.000"	""	"11"	"2"	"3"	"1"	"140"	"16.1"	"7.21"	"492.53"	"2.60"	"2"	"1"	"cell-cell signaling;cell organization and biogenesis;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;other cell component"	""	"Pf00595"	"51248"	"ENSG00000120509"	"PDZD11"	"D3DVU3; hsa:51248; Q5EBL8; Q6UWE1; Q9P0Q1"	"Ion transport by P-type ATPases; Ion influx/efflux at host-pathogen interface; Transport of vitamins, nucleosides, and related molecules; Biotin transport and metabolism; Vitamin B5 (pantothenate) metabolism"	""	"5"	"0"	"16.1"	"8.1"	"16.3"	"9.1"	"12.1"	"13.5"	"15.6"	"16.5"	"12.9"	"25.0"	"53.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95071"	"E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2"	"0.000"	""	"1"	"2"	"3"	"2"	"2799"	"309.2"	"5.85"	"592.52"	"2.60"	"2"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00632, Pf00658, Pf11547"	"51366"	"ENSG00000104517"	"UBR5"	"B2RP24; hsa:51366; J3KMW7; O94970; O95071; Q9NPL3"	""	"Mesodermal commitment pathway"	"1"	"0"	"117.6"	"62.2"	"126.5"	"105.9"	"117.7"	"153.3"	"106.6"	"128.4"	"116.7"	"233.2"	"350.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P47755"	"F-actin-capping protein subunit alpha-2 OS=Homo sapiens OX=9606 GN=CAPZA2 PE=1 SV=3"	"0.000"	""	"6"	"1"	"2"	"1"	"286"	"32.9"	"5.85"	"384.86"	"2.59"	"1"	"1"	"cell organization and biogenesis"	"non-structural extracellular;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf01267"	"830"	"ENSG00000198898"	"CAPZA2"	"B4DG50; hsa:830; P47755"	"MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Sensory processing of sound by inner hair cells of the cochlea; Factors involved in megakaryocyte development and platelet production; Advanced glycosylation endproduct receptor signaling"	""	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q14966"	"Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2"	""	""	"0"	"1"	"1"	"1"	"1978"	"220.5"	"6.38"	""	"2.59"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf12171"	"27332"	"ENSG00000075292"	"ZNF638"	"A0A096LPH6; B5MDV1; B7ZLD1; hsa:27332; Q14966; Q53R34; Q5XJ05; Q68DP3; Q6P2H2; Q7Z3T7; Q8NF92; Q8TCA1; Q9H2G1; Q9NP37"	"Transcriptional regulation of white adipocyte differentiation"	""	"1"	"0"	"93.5"	"33.8"	"80.1"	"57.9"	"77.4"	"80.9"	"58.8"	"85.1"	"77.4"	"200.5"	"474.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75962"	"Triple functional domain protein OS=Homo sapiens OX=9606 GN=TRIO PE=1 SV=2"	"0.000"	""	"0"	"1"	"2"	"1"	"3097"	"346.7"	"6.37"	"339.51"	"2.59"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00018, Pf00069, Pf00169, Pf00435, Pf00621, Pf00650, Pf07679, Pf16609"	"7204"	"ENSG00000038382"	"TRIO"	"D3DTD1; hsa:7204; O75962; Q13458; Q59EQ7; Q6PJC9; Q6ZN05; Q8IWK8"	"RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events; RHOG GTPase cycle; G alpha (q) signalling events; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOJ GTPase cycle; DCC mediated attractive signaling"	"Microtubule cytoskeleton regulation; Neural crest cell migration during development; Neural crest cell migration in cancer"	"14"	"0"	"12.9"	"6.9"	"12.5"	"8.0"	"11.7"	"11.7"	"9.3"	"16.5"	"35.8"	"74.8"	"143.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96FK6"	"WD repeat-containing protein 89 OS=Homo sapiens OX=9606 GN=WDR89 PE=2 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"387"	"43.2"	"6.13"	"303.57"	"2.58"	"1"	"1"	"developmental processes"	""	""	"Pf00400"	"112840"	"ENSG00000140006"	"WDR89"	"hsa:112840; Q96FK6"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8WU90"	"Zinc finger CCCH domain-containing protein 15 OS=Homo sapiens OX=9606 GN=ZC3H15 PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"426"	"48.6"	"5.31"	""	"2.58"	""	"1"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00642, Pf16543"	"55854"	"ENSG00000065548"	"ZC3H15"	"B4DMW2; D3DPG7; hsa:55854; Q5QTQ4; Q8WU90; Q8WZ06; Q9NUZ3; Q9NZ37; Q9P079"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"18.0"	"2.1"	"9.3"	"8.4"	"11.6"	"11.7"	"11.8"	"21.4"	"21.9"	"36.8"	"87.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TCJ2"	"Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B OS=Homo sapiens OX=9606 GN=STT3B PE=1 SV=1"	"0.001"	""	"1"	"1"	"2"	"1"	"826"	"93.6"	"8.91"	"253.73"	"2.57"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf02516"	"201595"	"ENSG00000163527"	"STT3B"	"hsa:201595; Q8TCJ2; Q96JZ4; Q96KY7"	""	"N-glycan biosynthesis"	"1"	"0"	"65.8"	"30.0"	"49.3"	"53.8"	"59.9"	"60.5"	"55.2"	"70.7"	"52.2"	"182.2"	"572.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N488"	"RING1 and YY1-binding protein OS=Homo sapiens OX=9606 GN=RYBP PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"228"	"24.8"	"9.63"	"308.00"	"2.57"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00641, Pf17219"	"23429"	"ENSG00000163602; ENSG00000281766"	"RYBP"	"hsa:23429; Q8N488; Q9P2W5; Q9UMW4"	"Transcriptional Regulation by E2F6; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"	""	"2"	"0"	"158.1"	"73.5"	"157.1"	"143.8"	"145.0"	"177.2"	"136.6"	"227.0"	"194.5"	"698.1"	"1568.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96GC5"	"39S ribosomal protein L48, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL48 PE=1 SV=2"	"0.000"	""	"5"	"1"	"2"	"1"	"212"	"23.9"	"8.98"	"296.01"	"2.57"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	""	"Pf00338"	"51642"	"ENSG00000175581"	"MRPL48"	"B4DN34; hsa:51642; Q49AK7; Q4U2Q4; Q96GC5; Q9P091; Q9Y5J0"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"13.2"	"7.4"	"10.2"	"11.0"	"11.0"	"11.0"	"9.4"	"14.0"	"9.7"	"35.3"	"59.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4J8"	"Dystrobrevin alpha OS=Homo sapiens OX=9606 GN=DTNA PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"743"	"83.8"	"6.89"	"316.36"	"2.56"	"1"	"1"	"cell-cell signaling;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00569, Pf09068, Pf09069"	"1837"	"ENSG00000134769"	"DTNA"	"A8K541; A8MSZ0; A8MUY4; B4DGS6; B4DIR0; B4DIU8; hsa:1837; M0QYX6; M0R397; O15332; O15333; O75697; Q13197; Q13198; Q13199; Q13498; Q13499; Q13500; Q59GK7; Q9BS59; Q9Y4J8"	""	"13q12.12 copy number variation"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3D9"	"28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2"	"0.000"	""	"5"	"1"	"2"	"1"	"190"	"21.8"	"8.90"	"293.11"	"2.56"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf10484"	"51649"	"ENSG00000181610"	"MRPS23"	"B2R6V3; hsa:51649; Q96Q24; Q9BWH8; Q9P053; Q9Y3D9"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"174.5"	"77.5"	"122.3"	"113.1"	"133.0"	"159.2"	"122.3"	"143.4"	"130.6"	"266.0"	"325.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49589"	"Cysteine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=CARS1 PE=1 SV=3"	"0.001"	""	"2"	"1"	"2"	"1"	"748"	"85.4"	"6.76"	"266.31"	"2.56"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01406"	"833"	"ENSG00000110619; ENSG00000278191"	"CARS1"	"hsa:833; P49589; Q53XI8; Q5HYE4; Q9HD24; Q9HD25"	"Cytosolic tRNA aminoacylation; Signaling by ALK fusions and activated point mutants"	""	"2"	"0"	"14.3"	"3.9"	"5.5"	"6.0"	"10.2"	"11.7"	"7.2"	"8.4"	"9.4"	"26.7"	"57.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q13616"	"Cullin-1 OS=Homo sapiens OX=9606 GN=CUL1 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"776"	"89.6"	"8.00"	""	"2.56"	""	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00888, Pf10557"	"8454"	"ENSG00000055130"	"CUL1"	"D3DWG3; hsa:8454; O60719; Q08AL6; Q13616; Q8IYW1"	"Nuclear events stimulated by ALK signaling in cancer; Circadian Clock; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; SCF-beta-TrCP mediated degradation of Emi1; Degradation of beta-catenin by the destruction complex; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; NIK-->noncanonical NF-kB signaling; Orc1 removal from chromatin; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Neddylation; SCF(Skp2)-mediated degradation of p27/p21; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Regulation of PLK1 Activity at G2/M Transition; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Cyclin D associated events in G1; Regulation of BACH1 activity; MAP3K8 (TPL2)-dependent MAPK1/3 activation; NOTCH1 Intracellular Domain Regulates Transcription; Prolactin receptor signaling; Iron uptake and transport; Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling"	"Cell cycle; TNF-alpha signaling pathway; Parkin-ubiquitin proteasomal system pathway; Apoptosis-related network due to altered Notch3 in ovarian cancer; Glucocorticoid receptor pathway; Nuclear receptors meta-pathway; Pleural mesothelioma; Notch signaling pathway"	"40"	"0"	"194.4"	"83.3"	"149.6"	"143.2"	"151.6"	"195.4"	"152.7"	"250.3"	"194.3"	"464.2"	"1233.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96QT6"	"PHD finger protein 12 OS=Homo sapiens OX=9606 GN=PHF12 PE=1 SV=2"	"0.001"	""	"1"	"1"	"2"	"1"	"1004"	"109.6"	"7.74"	"288.38"	"2.55"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00628, Pf16737"	"57649"	"ENSG00000109118"	"PHF12"	"hsa:57649; Q0VAI5; Q2TAK2; Q6ZML2; Q96QT6; Q9BV34; Q9H7U9; Q9P205"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6NUM9"	"All-trans-retinol 13,14-reductase OS=Homo sapiens OX=9606 GN=RETSAT PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"610"	"66.8"	"8.28"	"329.24"	"2.55"	"1"	"1"	"other metabolic processes"	"other membranes;ER/Golgi;nucleus"	"other molecular function"	"Pf13450"	"54884"	"ENSG00000042445"	"RETSAT"	"A6NIK3; hsa:54884; Q53R95; Q53SA9; Q6NUM9; Q6UX05; Q8N2H5; Q96FA4; Q9NXE5"	"Retinoid metabolism and transport"	"Vitamin A and carotenoid metabolism"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L9L4"	"MOB kinase activator 1B OS=Homo sapiens OX=9606 GN=MOB1B PE=1 SV=3"	"0.000"	""	"5"	"1"	"2"	"1"	"216"	"25.1"	"6.73"	"305.41"	"2.55"	"1"	"1"	"signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf03637"	"92597"	"ENSG00000173542"	"MOB1B"	"B2R8U6; B4DRY3; hsa:92597; Q7L9L4; Q8IY23"	"Signaling by Hippo"	"Pleural mesothelioma"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H6S0"	"3'-5' RNA helicase YTHDC2 OS=Homo sapiens OX=9606 GN=YTHDC2 PE=1 SV=2"	"0.001"	""	"1"	"1"	"2"	"1"	"1430"	"160.1"	"8.40"	"254.36"	"2.55"	"1"	"1"	"cell cycle OR cell proliferation;other biological processes"	"ER/Golgi;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf01424, Pf04146, Pf04408, Pf07717"	"64848"	"ENSG00000047188"	"YTHDC2"	"B2RP66; hsa:64848; Q9H6S0"	""	""	"0"	"0"	"21.2"	"4.4"	"21.0"	"12.2"	"19.1"	"21.0"	"14.8"	"18.8"	"13.8"	"29.1"	"51.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q6NYC1"	"Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 OS=Homo sapiens OX=9606 GN=JMJD6 PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"403"	"46.4"	"8.69"	""	"2.54"	""	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02373"	"23210"	"ENSG00000070495"	"JMJD6"	"B3KMN8; B4DGX1; hsa:23210; Q6NYC1; Q86VY0; Q8IUM5; Q9Y4E2"	"HDMs demethylate histones"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NW08"	"DNA-directed RNA polymerase III subunit RPC2 OS=Homo sapiens OX=9606 GN=POLR3B PE=1 SV=2"	"0.001"	""	"1"	"1"	"2"	"1"	"1133"	"127.7"	"8.50"	"272.75"	"2.54"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00562, Pf04560, Pf04561, Pf04563, Pf04565, Pf04566, Pf04567"	"55703"	"ENSG00000013503"	"POLR3B"	"A8K6H0; B3KV73; F5H1E6; hsa:55703; Q9NW08; Q9NW59"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway"	"10"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NFY9"	"Kelch repeat and BTB domain-containing protein 8 OS=Homo sapiens OX=9606 GN=KBTBD8 PE=1 SV=2"	"0.000"	""	"3"	"2"	"2"	"2"	"601"	"68.8"	"6.29"	"455.07"	"2.54"	"1"	"1"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	""	"Pf00651, Pf01344, Pf07707"	"84541"	"ENSG00000163376"	"KBTBD8"	"B4DTW6; hsa:84541; Q8NFY9; Q96JI5"	"Antigen processing: Ubiquitination & Proteasome degradation; Neddylation"	""	"2"	"0"	"37.6"	"20.4"	"30.9"	"34.7"	"38.0"	"54.4"	"72.1"	"287.5"	"404.0"	"917.0"	"1314.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q7Z392"	"Trafficking protein particle complex subunit 11 OS=Homo sapiens OX=9606 GN=TRAPPC11 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1133"	"128.8"	"7.14"	""	"2.54"	""	"1"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;ER/Golgi;other cell component"	""	"Pf11817, Pf12742"	"60684"	"ENSG00000168538"	"TRAPPC11"	"A4QPB8; B2RCD6; hsa:60684; Q5U5I7; Q6FI73; Q7Z392; Q86T25; Q9H0L1; Q9H5K9; Q9H8Q1; Q9H9I7"	"RAB GEFs exchange GTP for GDP on RABs"	"Genes related to primary cilium development (based on CRISPR)"	"2"	"0"	"4.2"	"0.0"	"3.2"	"3.0"	"4.8"	"9.8"	"5.4"	"4.5"	"6.2"	"20.1"	"73.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95721"	"Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"258"	"29.0"	"5.81"	"311.40"	"2.54"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	""	"9342"	"ENSG00000099940"	"SNAP29"	"hsa:9342; O95721"	"Neutrophil degranulation; Intra-Golgi traffic"	"Ciliary landscape; 22q11.2 copy number variation syndrome"	"4"	"0"	"18.2"	"7.3"	"19.2"	"18.8"	"14.2"	"23.6"	"18.1"	"18.1"	"15.1"	"23.3"	"28.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P51003"	"Poly(A) polymerase alpha OS=Homo sapiens OX=9606 GN=PAPOLA PE=1 SV=4"	""	""	"1"	"1"	"1"	"1"	"745"	"82.8"	"7.37"	""	"2.53"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01909, Pf04926, Pf04928"	"10914"	"ENSG00000090060"	"PAPOLA"	"hsa:10914; P51003; Q86SX4; Q86TV0; Q8IYF5; Q9BVU2"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"mRNA processing"	"5"	"0"	"10.7"	"4.7"	"9.6"	"6.1"	"7.7"	"10.9"	"9.0"	"14.3"	"7.3"	"41.5"	"148.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62273"	"40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2"	"0.000"	""	"30"	"2"	"2"	"2"	"56"	"6.7"	"10.13"	"310.98"	"2.53"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00253"	"6235"	"ENSG00000213741"	"RPS29"	"A8MZ73; hsa:6235; P30054; P62273"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"255.2"	"112.4"	"258.1"	"223.2"	"241.2"	"290.1"	"225.9"	"304.9"	"214.2"	"418.5"	"514.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49591"	"Serine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=SARS1 PE=1 SV=3"	"0.000"	""	"5"	"2"	"3"	"2"	"514"	"58.7"	"6.43"	"764.19"	"2.53"	"2"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00587, Pf02403"	"6301"	"ENSG00000031698"	"SARS1"	"B2R6Y9; hsa:6301; P49591; Q5T5C8; Q9NSE3"	"Cytosolic tRNA aminoacylation; Selenocysteine synthesis"	"VEGFA-VEGFR2 signaling"	"3"	"0"	"50.1"	"21.7"	"37.1"	"34.0"	"36.5"	"49.1"	"41.8"	"51.4"	"45.1"	"81.7"	"283.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O60488"	"Long-chain-fatty-acid--CoA ligase 4 OS=Homo sapiens OX=9606 GN=ACSL4 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"711"	"79.1"	"8.38"	""	"2.53"	""	"1"	"other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00501"	"2182"	"ENSG00000068366"	"ACSL4"	"D3DUY2; hsa:2182; O60488; O60848; O60849; Q5JWV8"	"Synthesis of very long-chain fatty acyl-CoAs; Intracellular metabolism of fatty acids regulates insulin secretion"	"Fatty acid beta-oxidation; Fatty acid biosynthesis; Mitochondrial long chain fatty acid beta-oxidation; PPAR signaling pathway; Ferroptosis; Thermogenesis; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Omega-3 / omega-6 fatty acid synthesis; Omega-9 fatty acid synthesis; Fatty acid transporters; Mitochondrial fatty acid oxidation disorders"	"13"	"0"	"41.7"	"16.0"	"46.8"	"42.2"	"47.0"	"42.3"	"33.6"	"51.4"	"36.8"	"81.4"	"148.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P04632"	"Calpain small subunit 1 OS=Homo sapiens OX=9606 GN=CAPNS1 PE=1 SV=1"	""	""	"9"	"1"	"1"	"1"	"268"	"28.3"	"5.20"	""	"2.53"	""	"1"	"protein metabolism;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	""	"826"	"ENSG00000126247"	"CAPNS1"	"A8K0P1; hsa:826; P04632; Q8WTX3; Q96EW0"	"Degradation of the extracellular matrix; Formation of the cornified envelope; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"	"Integrin-mediated cell adhesion"	"4"	"0"	"139.4"	"45.5"	"77.0"	"43.4"	"71.4"	"61.8"	"62.9"	"69.7"	"72.7"	"134.2"	"215.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z4Q2"	"HEAT repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=HEATR3 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"680"	"74.5"	"5.11"	"299.70"	"2.53"	"1"	"1"	"transport;other biological processes"	""	"other molecular function"	"Pf13513"	"55027"	"ENSG00000155393"	"HEATR3"	"A8K1N4; hsa:55027; Q7Z4Q2; Q8N525; Q8WV56; Q96CC9; Q9NWN7"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13409"	"Cytoplasmic dynein 1 intermediate chain 2 OS=Homo sapiens OX=9606 GN=DYNC1I2 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"638"	"71.4"	"5.20"	"309.18"	"2.52"	"1"	"1"	"transport;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf11540"	"1781"	"ENSG00000077380"	"DYNC1I2"	"B7ZA04; D3DPD4; D3DPD5; D3DPD6; hsa:1781; Q13409; Q32LY9; Q53S84; Q5BJF8; Q7Z4X1; Q96NG7; Q96S87; Q9BXZ5; Q9NT58"	"HCMV Early Events; Separation of Sister Chromatids; Aggrephagy; Regulation of PLK1 Activity at G2/M Transition; RHO GTPases Activate Formins; COPI-mediated anterograde transport; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recruitment of NuMA to mitotic centrosomes; COPI-independent Golgi-to-ER retrograde traffic; EML4 and NUDC in mitotic spindle formation; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein"	"21"	"0"	"243.0"	"86.3"	"204.3"	"169.9"	"183.0"	"211.8"	"156.4"	"203.2"	"172.4"	"338.0"	"565.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15542"	"Transcription initiation factor TFIID subunit 5 OS=Homo sapiens OX=9606 GN=TAF5 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"800"	"86.8"	"5.64"	"282.68"	"2.51"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00400, Pf04494"	"6877"	"ENSG00000148835"	"TAF5"	"A8K5B4; B2RMR0; B7ZKJ6; hsa:6877; Q15542; Q53EM4; Q5SYD5; Q86UZ7; Q9Y4K5"	"RNA Polymerase II Pre-transcription Events; RNA polymerase II transcribes snRNA genes; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Regulation of TP53 Activity through Phosphorylation"	"Eukaryotic transcription initiation"	"11"	"0"	"164.5"	"59.0"	"133.2"	"116.2"	"125.6"	"151.0"	"101.0"	"160.7"	"109.8"	"215.9"	"353.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51665"	"26S proteasome non-ATPase regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMD7 PE=1 SV=2"	"0.001"	""	"3"	"1"	"2"	"1"	"324"	"37.0"	"6.77"	"235.31"	"2.51"	"1"	"1"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf01398, Pf13012"	"5713"	"ENSG00000103035"	"PSMD7"	"D3DWS9; hsa:5713; P51665; Q6PKI2; Q96E97"	"Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Neutrophil degranulation; Regulation of expression of SLITs and ROBOs; Orc1 removal from chromatin; Assembly of the pre-replicative complex; Degradation of GLI1 by the proteasome; Hedgehog 'on' state; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"65"	"0"	"24.1"	"9.8"	"18.6"	"12.7"	"15.0"	"20.5"	"14.7"	"24.1"	"17.8"	"52.8"	"108.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O95456"	"Proteasome assembly chaperone 1 OS=Homo sapiens OX=9606 GN=PSMG1 PE=1 SV=1"	""	""	"7"	"1"	"1"	"1"	"288"	"32.8"	"7.17"	""	"2.51"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf16094"	"8624"	"ENSG00000183527"	"PSMG1"	"B5BUN2; hsa:8624; O95456; Q6FHA3; Q6FHD3; Q6S713"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q13188"	"Serine/threonine-protein kinase 3 OS=Homo sapiens OX=9606 GN=STK3 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"491"	"56.3"	"5.24"	""	"2.51"	""	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf11629"	"6788"	"ENSG00000104375"	"STK3"	"A8K722; B3KYA7; hsa:6788; Q13188; Q15445; Q15801; Q96FM6"	"Signaling by Hippo"	"MAPK signaling pathway; Transcription co-factors SKI and SKIL protein partners; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-YAP signaling; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; Leukocyte-intrinsic Hippo pathway functions; Pleural mesothelioma"	"9"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P031"	"Thyroid transcription factor 1-associated protein 26 OS=Homo sapiens OX=9606 GN=CCDC59 PE=1 SV=2"	"0.001"	""	"5"	"1"	"2"	"1"	"241"	"28.7"	"9.88"	"241.39"	"2.51"	"1"	"1"	""	"nucleus"	""	"Pf08524"	"29080"	"ENSG00000133773"	"CCDC59"	"hsa:29080; Q9H2V5; Q9NW62; Q9P031"	"Surfactant metabolism"	""	"1"	"0"	"17.5"	"8.3"	"15.0"	"10.1"	"11.1"	"10.9"	"8.6"	"9.5"	"11.5"	"23.7"	"40.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O00255"	"Menin OS=Homo sapiens OX=9606 GN=MEN1 PE=1 SV=4"	""	""	"2"	"1"	"1"	"1"	"615"	"68.0"	"6.55"	""	"2.51"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05053"	"4221"	"ENSG00000133895"	"MEN1"	"A5HBC6; A5HBC7; A5HBC8; A5HBC9; A5HBD0; A5HBD1; A5HBD2; hsa:4221; O00255; O00632; Q9BUF0; Q9BUK2"	"RHO GTPases activate IQGAPs; Formation of WDR5-containing histone-modifying complexes; Formation of the beta-catenin:TCF transactivating complex; SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Deactivation of the beta-catenin transactivating complex; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation"	"10q11.21q11.23 copy number variation syndrome"	"8"	"0"	"29.3"	"13.9"	"27.7"	"24.0"	"31.0"	"23.1"	"15.4"	"28.0"	"23.1"	"45.7"	"81.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q03164"	"Histone-lysine N-methyltransferase 2A OS=Homo sapiens OX=9606 GN=KMT2A PE=1 SV=5"	""	""	"0"	"1"	"1"	"1"	"3969"	"431.5"	"9.09"	""	"2.50"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00628, Pf00856, Pf02008, Pf05964, Pf05965, Pf13771"	"4297"	"ENSG00000118058"	"KMT2A"	"E9PQG7; hsa:4297; Q03164; Q13743; Q13744; Q14845; Q16364; Q59FF2; Q6UBD1; Q9HBJ3; Q9UD94; Q9UMA3"	"Formation of WDR5-containing histone-modifying complexes; RUNX1 regulates transcription of genes involved in differentiation of HSCs; PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Transcriptional regulation of granulopoiesis"	"Histone modifications"	"6"	"0"	"9.6"	"3.9"	"11.6"	"7.1"	"11.0"	"9.6"	"7.2"	"10.3"	"7.5"	"17.0"	"30.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O95985"	"DNA topoisomerase 3-beta-1 OS=Homo sapiens OX=9606 GN=TOP3B PE=1 SV=1"	""	""	"1"	"1"	"1"	"1"	"862"	"96.6"	"8.12"	""	"2.50"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01131, Pf01751"	"8940"	"ENSG00000100038"	"TOP3B"	"A0M8Q3; hsa:8940; O95985; Q9BUP5"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P49773"	"Histidine triad nucleotide-binding protein 1 OS=Homo sapiens OX=9606 GN=HINT1 PE=1 SV=2"	""	""	"6"	"1"	"1"	"1"	"126"	"13.8"	"6.95"	""	"2.49"	""	"1"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf01230"	"3094"	"ENSG00000169567"	"HINT1"	"hsa:3094; P49773; Q9H5W8"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96DV4"	"39S ribosomal protein L38, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL38 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"380"	"44.6"	"7.53"	"309.79"	"2.49"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	""	"Pf01161"	"64978"	"ENSG00000204316"	"MRPL38"	"B3KN96; hsa:64978; Q96DV4; Q96Q66; Q9P0B9"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"83.2"	"23.3"	"76.9"	"60.4"	"64.8"	"92.0"	"61.9"	"53.7"	"61.8"	"65.0"	"122.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NZI7"	"Upstream-binding protein 1 OS=Homo sapiens OX=9606 GN=UBP1 PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"540"	"60.5"	"6.35"	""	"2.48"	""	"1"	"developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04516, Pf18016"	"7342"	"ENSG00000153560"	"UBP1"	"hsa:7342; Q68CT0; Q86Y57; Q9H8V0; Q9NZI7; Q9UD76; Q9UD78"	""	""	"0"	"0"	"9.9"	"5.8"	"7.4"	"2.0"	"5.9"	"9.9"	"10.0"	"11.7"	"16.1"	"60.6"	"111.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q14C86"	"GTPase-activating protein and VPS9 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=GAPVD1 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1478"	"164.9"	"5.22"	""	"2.48"	""	"1"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00616, Pf02204, Pf18151"	"26130"	"ENSG00000165219"	"GAPVD1"	"A8MYK3; B0QZ62; B0QZ63; B0QZ64; hsa:26130; Q14C76; Q14C86; Q2Q1W1; Q8ND92; Q8WU86; Q96CZ4; Q9NXQ1; Q9P207; Q9Y4N0"	"RAB GEFs exchange GTP for GDP on RABs; Clathrin-mediated endocytosis"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96DE5"	"Anaphase-promoting complex subunit 16 OS=Homo sapiens OX=9606 GN=ANAPC16 PE=1 SV=1"	"0.001"	""	"14"	"1"	"2"	"1"	"110"	"11.7"	"4.97"	"239.87"	"2.47"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf17256"	"119504"	"ENSG00000166295"	"ANAPC16"	"hsa:119504; Q96DE5"	"Separation of Sister Chromatids; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; CDK-mediated phosphorylation and removal of Cdc6; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of Cyclin B; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; Regulation of APC/C activators between G1/S and early anaphase; Phosphorylation of the APC/C; APC-Cdc20 mediated degradation of Nek2A; Senescence-Associated Secretory Phenotype (SASP); Transcriptional Regulation by VENTX; Aberrant regulation of mitotic exit in cancer due to RB1 defects"	""	"17"	"0"	"25.2"	"8.0"	"19.4"	"22.1"	"16.1"	"18.3"	"19.8"	"25.5"	"20.3"	"52.4"	"80.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WYQ5"	"Microprocessor complex subunit DGCR8 OS=Homo sapiens OX=9606 GN=DGCR8 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"773"	"86.0"	"5.95"	"360.73"	"2.47"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00035"	"54487"	"ENSG00000128191"	"DGCR8"	"B2R8G1; hsa:54487; Q6DCB2; Q6MZE9; Q6Y2L0; Q8WYQ5; Q96G39; Q96GP8; Q9H6L8; Q9H6T7; Q9NRW2"	"Transcriptional Regulation by MECP2; MicroRNA (miRNA) biogenesis"	"miRNA biogenesis; exRNA mechanism of action and biogenesis; DDX1 as a regulatory component of the Drosha microprocessor; 22q11.2 copy number variation syndrome"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96MN5"	"Transcription elongation factor A N-terminal and central domain-containing protein 2 OS=Homo sapiens OX=9606 GN=TCEANC2 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"208"	"24.1"	"10.05"	"302.53"	"2.47"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf08711"	"127428"	"ENSG00000116205"	"TCEANC2"	"hsa:127428; Q5T702; Q8N8N2; Q96MN5"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HC35"	"Echinoderm microtubule-associated protein-like 4 OS=Homo sapiens OX=9606 GN=EML4 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"981"	"108.8"	"6.40"	"314.44"	"2.47"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf03451, Pf07714"	"27436"	"ENSG00000143924"	"EML4"	"A6H8Y6; A6P4T4; A6P4V4; B2RBK3; B2RTW7; B5MCW9; hsa:27436; Q3SWW0; Q53R29; Q53TW8; Q6PJ45; Q9HC35; Q9NV40"	"EML4 and NUDC in mitotic spindle formation; ALK mutants bind TKIs; Nuclear events stimulated by ALK signaling in cancer"	"Non-small cell lung cancer"	"5"	"0"	"72.3"	"34.7"	"43.4"	"34.9"	"48.0"	"47.9"	"52.0"	"75.2"	"56.5"	"66.2"	"98.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P26374"	"Rab proteins geranylgeranyltransferase component A 2 OS=Homo sapiens OX=9606 GN=CHML PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"656"	"74.0"	"4.93"	""	"2.46"	""	"1"	"protein metabolism;other metabolic processes;transport;signal transduction"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00996"	"1122"	"ENSG00000203668"	"CHML"	"B2RAB9; hsa:1122; P26374; Q17RE0; Q9H1Y4"	"RAB GEFs exchange GTP for GDP on RABs; RAB geranylgeranylation"	""	"2"	"0"	"26.4"	"15.2"	"27.3"	"19.2"	"25.5"	"27.1"	"28.5"	"49.4"	"87.0"	"229.5"	"326.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75569"	"Interferon-inducible double-stranded RNA-dependent protein kinase activator A OS=Homo sapiens OX=9606 GN=PRKRA PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"313"	"34.4"	"8.41"	"418.27"	"2.46"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00035"	"8575"	"ENSG00000180228"	"PRKRA"	"A8K3I6; hsa:8575; O75569; Q53G24; Q6X7T5; Q8NDK4"	"MicroRNA (miRNA) biogenesis; Small interfering RNA (siRNA) biogenesis"	"VEGFA-VEGFR2 signaling; Ebola virus infection in host"	"4"	"0"	"111.2"	"37.9"	"73.6"	"82.2"	"74.6"	"85.4"	"76.1"	"85.0"	"80.3"	"213.8"	"524.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q99627"	"COP9 signalosome complex subunit 8 OS=Homo sapiens OX=9606 GN=COPS8 PE=1 SV=1"	""	""	"5"	"1"	"1"	"1"	"209"	"23.2"	"5.38"	""	"2.46"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf10075"	"10920"	"ENSG00000198612"	"COPS8"	"A8K1H6; hsa:10920; Q53QS9; Q99627"	"Cargo recognition for clathrin-mediated endocytosis; Neddylation; Formation of TC-NER Pre-Incision Complex; DNA Damage Recognition in GG-NER"	"Ciliary landscape; 2q37 copy number variation syndrome"	"6"	"0"	"46.5"	"16.1"	"41.3"	"31.9"	"38.4"	"46.3"	"45.5"	"64.3"	"55.9"	"115.3"	"258.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P11274"	"Breakpoint cluster region protein OS=Homo sapiens OX=9606 GN=BCR PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1271"	"142.7"	"7.03"	""	"2.44"	""	"1"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00168, Pf00620, Pf00621, Pf09036, Pf19057"	"613"	"ENSG00000186716"	"BCR"	"hsa:613; P11274; P78501; Q12842; Q4LE80; Q6NZI3"	"RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOB GTPase cycle; Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease"	"Imatinib and chronic myeloid leukemia; Extrafollicular and follicular B cell activation by SARS-CoV-2"	"11"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49454"	"Centromere protein F OS=Homo sapiens OX=9606 GN=CENPF PE=1 SV=3"	"0.000"	""	"1"	"3"	"4"	"2"	"3114"	"357.3"	"5.10"	"869.97"	"2.44"	"3"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf10473, Pf10481, Pf10490"	"1063"	"ENSG00000117724"	"CENPF"	"hsa:1063; P49454; Q13171; Q13246; Q5VVM7"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Polo-like kinase mediated events"	"Gastric cancer network 1; Ciliopathies"	"9"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18206"	"Vinculin OS=Homo sapiens OX=9606 GN=VCL PE=1 SV=4"	"0.001"	""	"1"	"1"	"2"	"1"	"1134"	"123.7"	"5.66"	"283.57"	"2.44"	"1"	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01044"	"7414"	"ENSG00000035403"	"VCL"	"hsa:7414; P18206; Q16450; Q5SWX2; Q7Z3B8; Q8IXU7"	"Platelet degranulation ; Neutrophil degranulation; Signaling by BRAF and RAF1 fusions; Signaling by ALK fusions and activated point mutants; Smooth Muscle Contraction; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants"	"Integrin-mediated cell adhesion; Primary focal segmental glomerulosclerosis (FSGS); Focal adhesion; VEGFA-VEGFR2 signaling; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Melanoma; Regulation of actin cytoskeleton"	"18"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UPY8"	"Microtubule-associated protein RP/EB family member 3 OS=Homo sapiens OX=9606 GN=MAPRE3 PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"281"	"32.0"	"5.54"	""	"2.43"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf03271"	"22924"	"ENSG00000084764"	"MAPRE3"	"B7WPK5; hsa:22924; O00265; Q6FHB0; Q6FI15; Q9BZP7; Q9BZP8; Q9UPY8"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q5T7N3"	"KN motif and ankyrin repeat domain-containing protein 4 OS=Homo sapiens OX=9606 GN=KANK4 PE=1 SV=1"	""	""	"1"	"1"	"1"	"1"	"995"	"107.3"	"5.27"	""	"2.43"	""	"1"	"cell organization and biogenesis"	"cytosol;cytoskeleton;other cell component"	""	"Pf00023, Pf12075, Pf13857"	"163782"	"ENSG00000132854"	"KANK4"	"B1ALP7; hsa:163782; Q5T7N3; Q6P9A0; Q86T71; Q86VE6; Q8NAX3"	""	""	"0"	"0"	"117.0"	"39.5"	"82.9"	"64.8"	"83.6"	"82.1"	"54.7"	"75.2"	"57.8"	"116.3"	"160.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H3P2"	"Negative elongation factor A OS=Homo sapiens OX=9606 GN=NELFA PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"528"	"57.2"	"9.03"	"348.93"	"2.43"	"1"	"1"	"other biological processes"	"cytosol;nucleus"	"other molecular function"	""	"7469"	"ENSG00000185049"	"NELFA"	"A2A2T1; hsa:7469; O95392; Q9H3P2"	"Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; TP53 Regulates Transcription of DNA Repair Genes"	"Initiation of transcription and translation elongation at the HIV-1 LTR; 4p16.3 copy number variation"	"16"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82930"	"28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"218"	"25.6"	"9.98"	"315.34"	"2.43"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf16053"	"65993"	"ENSG00000074071"	"MRPS34"	"hsa:65993; P82930; Q9BVI7"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"213.1"	"100.4"	"175.6"	"154.1"	"158.0"	"187.6"	"144.4"	"192.4"	"142.4"	"322.8"	"471.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IX18"	"Probable ATP-dependent RNA helicase DHX40 OS=Homo sapiens OX=9606 GN=DHX40 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"779"	"88.5"	"8.65"	"297.21"	"2.43"	"1"	"1"	""	""	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"79665"	"ENSG00000108406"	"DHX40"	"B3KTJ5; C9JR60; hsa:79665; Q5JPH4; Q8IX18; Q8TC86; Q8WY53; Q9BXM1; Q9H6M9"	""	""	"0"	"0"	"12.0"	"5.1"	"11.8"	"6.0"	"6.4"	"8.3"	"6.0"	"9.0"	"12.1"	"19.7"	"31.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UGM6"	"Tryptophan--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=WARS2 PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"360"	"40.1"	"9.28"	""	"2.43"	""	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf00579"	"10352"	"ENSG00000116874"	"WARS2"	"B1ALR1; B2R9D4; hsa:10352; Q53FT4; Q5VUD2; Q86TQ0; Q9UGM6"	"Mitochondrial tRNA aminoacylation"	""	"1"	"0"	"45.8"	"23.0"	"52.4"	"46.2"	"51.6"	"58.6"	"37.0"	"51.5"	"48.5"	"135.8"	"305.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q05682"	"Caldesmon OS=Homo sapiens OX=9606 GN=CALD1 PE=1 SV=3"	"0.000"	""	"3"	"3"	"4"	"3"	"793"	"93.2"	"5.66"	"837.44"	"2.43"	"3"	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton"	"cytoskeletal activity;other molecular function"	"Pf02029"	"800"	"ENSG00000122786"	"CALD1"	"A8K0X1; hsa:800; Q05682; Q13978; Q13979; Q14741; Q14742; Q9UD91"	"Smooth Muscle Contraction"	"Myometrial relaxation and contraction pathways"	"2"	"0"	"525.3"	"157.1"	"407.4"	"345.7"	"408.9"	"443.1"	"314.4"	"437.3"	"249.2"	"859.7"	"4682.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00299"	"Chloride intracellular channel protein 1 OS=Homo sapiens OX=9606 GN=CLIC1 PE=1 SV=4"	"0.000"	""	"4"	"1"	"2"	"1"	"241"	"26.9"	"5.17"	"281.17"	"2.43"	"1"	"1"	"transport;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;mitochondrion;nucleus;other cell component"	"transporter activity"	"Pf13409, Pf13410"	"1192"	"ENSG00000206394; ENSG00000213719; ENSG00000223639; ENSG00000226248; ENSG00000226417; ENSG00000226651; ENSG00000230685"	"CLIC1"	"hsa:1192; O00299; Q15089; Q502X1"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"65.8"	"39.0"	"59.6"	"40.2"	"57.6"	"61.4"	"61.9"	"64.3"	"73.6"	"144.6"	"250.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IVD9"	"NudC domain-containing protein 3 OS=Homo sapiens OX=9606 GN=NUDCD3 PE=1 SV=3"	"0.000"	""	"6"	"2"	"4"	"2"	"361"	"40.8"	"5.25"	"529.62"	"2.43"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;other cell component"	"other molecular function"	"Pf04969, Pf14050"	"23386"	"ENSG00000015676"	"NUDCD3"	"hsa:23386; Q8IVD9; Q9BTI3; Q9H7W9; Q9UPT4"	""	""	"0"	"0"	"99.0"	"37.7"	"80.4"	"65.7"	"87.1"	"98.2"	"64.0"	"99.7"	"93.6"	"1063.7"	"2046.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P10619"	"Lysosomal protective protein OS=Homo sapiens OX=9606 GN=CTSA PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"480"	"54.4"	"6.61"	"293.93"	"2.42"	"1"	"1"	"protein metabolism;transport;other biological processes"	"non-structural extracellular;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00450"	"5476"	"ENSG00000064601"	"CTSA"	"B2R798; hsa:5476; P10619; Q561W6; Q5JZH1; Q96KJ2; Q9BR08; Q9BW68"	"MHC class II antigen presentation; Neutrophil degranulation; Glycosphingolipid metabolism; Sialic acid metabolism; Defective NEU1 causes sialidosis"	"Ciliary landscape"	"6"	"0"	"11.6"	"4.0"	"9.8"	"5.9"	"16.4"	"15.3"	"7.5"	"7.8"	"12.8"	"11.5"	"23.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q7KZI7"	"Serine/threonine-protein kinase MARK2 OS=Homo sapiens OX=9606 GN=MARK2 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"788"	"87.9"	"9.72"	""	"2.42"	""	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;kinase activity;other molecular function"	"Pf00069, Pf00627, Pf02149"	"2011"	"ENSG00000072518"	"MARK2"	"hsa:2011; Q15449; Q15524; Q5XGA3; Q68A18; Q7KZI7; Q96HB3; Q96RG0"	""	"Microtubule cytoskeleton regulation; Complement system in neuronal development and plasticity; Neurogenesis regulation in the olfactory epithelium"	"3"	"0"	"28.1"	"16.9"	"29.7"	"30.0"	"22.4"	"32.8"	"28.6"	"31.8"	"31.7"	"69.9"	"112.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15102"	"Platelet-activating factor acetylhydrolase IB subunit gamma OS=Homo sapiens OX=9606 GN=PAFAH1B3 PE=1 SV=1"	"0.001"	""	"4"	"1"	"2"	"1"	"231"	"25.7"	"6.84"	"249.70"	"2.42"	"1"	"1"	"other metabolic processes;developmental processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf13472"	"5050"	"ENSG00000079462"	"PAFAH1B3"	"hsa:5050; Q15102; Q53X88"	"COPI-independent Golgi-to-ER retrograde traffic"	"PAFAH1B1 copy number variation"	"2"	"0"	"26.0"	"7.3"	"15.5"	"16.5"	"13.5"	"15.8"	"15.0"	"21.4"	"19.1"	"38.9"	"65.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18077"	"60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2"	"0.000"	""	"13"	"2"	"3"	"2"	"110"	"12.5"	"11.06"	"471.52"	"2.42"	"2"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01247"	"6165"	"ENSG00000182899"	"RPL35A"	"hsa:6165; P18077; Q08ES9; Q9BVN7"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"445.5"	"188.3"	"367.9"	"304.9"	"347.0"	"425.1"	"331.1"	"473.6"	"418.2"	"667.6"	"763.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14578"	"Citron Rho-interacting kinase OS=Homo sapiens OX=9606 GN=CIT PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"2027"	"231.3"	"6.57"	"303.87"	"2.42"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf00169, Pf00780"	"11113"	"ENSG00000122966"	"CIT"	"hsa:11113; O14578; Q2M5E1; Q6XUH8; Q86UQ9; Q9UPZ7"	"RHOC GTPase cycle; RHOA GTPase cycle; RAC1 GTPase cycle; RHOB GTPase cycle; RHO GTPases activate CIT"	"Pleural mesothelioma; G13 signaling pathway"	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2Z0"	"Protein SGT1 homolog OS=Homo sapiens OX=9606 GN=SUGT1 PE=1 SV=3"	"0.001"	""	"2"	"1"	"2"	"1"	"365"	"41.0"	"5.16"	"273.72"	"2.42"	"1"	"1"	"cell cycle OR cell proliferation;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf04969, Pf05002"	"10910"	"ENSG00000165416"	"SUGT1"	"A2A303; hsa:10910; Q5JAK5; Q5TAM6; Q6VXY6; Q9Y2Z0"	"The NLRP3 inflammasome; Purinergic signaling in leishmaniasis infection"	"Nucleotide-binding oligomerization domain (NOD) pathway"	"3"	"0"	"70.8"	"26.2"	"65.7"	"57.1"	"70.5"	"70.4"	"63.2"	"107.6"	"79.1"	"235.9"	"367.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92759"	"General transcription factor IIH subunit 4 OS=Homo sapiens OX=9606 GN=GTF2H4 PE=1 SV=1"	"0.001"	""	"3"	"1"	"2"	"1"	"462"	"52.2"	"9.04"	"286.95"	"2.42"	"1"	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03849, Pf18307"	"2968"	"ENSG00000213780; ENSG00000221974; ENSG00000226384; ENSG00000233149; ENSG00000234370; ENSG00000236895"	"GTF2H4"	"B4DTJ5; hsa:2968; Q76KU4; Q92759"	"RNA Polymerase I Transcription Initiation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Dual Incision in GG-NER; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"Eukaryotic transcription initiation; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"33"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P32780"	"General transcription factor IIH subunit 1 OS=Homo sapiens OX=9606 GN=GTF2H1 PE=1 SV=1"	"0.000"	""	"3"	"2"	"3"	"2"	"548"	"62.0"	"8.66"	"583.21"	"2.41"	"2"	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus"	"other molecular function"	"Pf03909, Pf08567"	"2965"	"ENSG00000110768; ENSG00000288114"	"GTF2H1"	"B3KXE0; D3DQY2; hsa:2965; P32780; Q6I9Y7; Q9H5K5; Q9NQD9"	"NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Dual Incision in GG-NER"	"Eukaryotic transcription initiation; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"33"	"0"	"76.0"	"33.5"	"87.6"	"84.5"	"85.8"	"94.8"	"105.0"	"210.6"	"336.5"	"1158.8"	"909.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BRK5"	"45 kDa calcium-binding protein OS=Homo sapiens OX=9606 GN=SDF4 PE=1 SV=1"	"0.001"	""	"2"	"1"	"2"	"1"	"362"	"41.8"	"4.86"	"290.01"	"2.41"	"1"	"1"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf13202, Pf13499"	"51150"	""	"SDF4"	"B1AME5; B1AME6; B2RDF1; B4DSM1; hsa:51150; Q53G52; Q53HQ9; Q8NBQ3; Q96AA1; Q9BRK5; Q9NZP7; Q9UN53"	""	""	"0"	"0"	"97.4"	"49.6"	"105.1"	"81.1"	"94.8"	"118.9"	"89.0"	"93.0"	"73.7"	"162.0"	"184.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96E11"	"Ribosome-recycling factor, mitochondrial OS=Homo sapiens OX=9606 GN=MRRF PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"262"	"29.3"	"9.79"	"331.15"	"2.41"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"mitochondrion"	"translation activity"	"Pf01765"	"92399"	"ENSG00000148187"	"MRRF"	"A8K6D8; A8K6Z4; B7Z4X5; B7Z6P7; hsa:92399; Q5RKT1; Q5T7T0; Q5T7T1; Q5T7T2; Q5T7T3; Q5T7T4; Q5T7T5; Q96E11"	"Mitochondrial translation termination"	""	"1"	"0"	"55.3"	"20.0"	"32.4"	"29.5"	"39.2"	"42.4"	"30.9"	"42.9"	"39.4"	"226.8"	"631.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6PI98"	"INO80 complex subunit C OS=Homo sapiens OX=9606 GN=INO80C PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"192"	"20.6"	"10.02"	"382.61"	"2.41"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus"	""	"Pf08265"	"125476"	"ENSG00000153391"	"INO80C"	"B4DUI4; E9PCS7; hsa:125476; Q6PI98; Q86WR1; Q8N994"	"UCH proteinases; DNA Damage Recognition in GG-NER"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"A6NED2"	"RCC1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RCCD1 PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"376"	"40.1"	"5.27"	""	"2.41"	""	"1"	"cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf00415"	"91433"	"ENSG00000166965"	"RCCD1"	"A6NED2; B2RTP9; hsa:91433; Q29RX6"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13643"	"Four and a half LIM domains protein 3 OS=Homo sapiens OX=9606 GN=FHL3 PE=1 SV=4"	"0.001"	""	"3"	"1"	"2"	"1"	"280"	"31.2"	"6.20"	"239.32"	"2.41"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus"	"cytoskeletal activity;other molecular function"	"Pf00412"	"2275"	"ENSG00000183386"	"FHL3"	"D3DPT6; hsa:2275; Q13643; Q6I9T0; Q9BVA2"	""	""	"0"	"0"	"82.3"	"32.3"	"84.5"	"75.8"	"87.8"	"87.6"	"69.2"	"92.1"	"91.6"	"160.4"	"197.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5Q9"	"General transcription factor 3C polypeptide 3 OS=Homo sapiens OX=9606 GN=GTF3C3 PE=1 SV=1"	"0.001"	""	"1"	"1"	"2"	"1"	"886"	"101.2"	"5.07"	"272.20"	"2.41"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13181"	"9330"	"ENSG00000119041"	"GTF3C3"	"hsa:9330; Q4ZG48; Q86XJ8; Q8WX84; Q96B44; Q9H5I8; Q9NT97; Q9Y5Q9"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter"	""	"3"	"0"	"115.3"	"56.1"	"88.4"	"92.7"	"110.6"	"105.9"	"85.5"	"113.6"	"91.9"	"177.0"	"334.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q0ZGT2"	"Nexilin OS=Homo sapiens OX=9606 GN=NEXN PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"675"	"80.6"	"5.33"	"278.45"	"2.41"	"1"	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf07679"	"91624"	"ENSG00000162614"	"NEXN"	"A0PJ84; B4DPZ7; hsa:91624; Q0D2H2; Q0ZGT2; Q14CC2; Q14CC3; Q16081; Q7Z2X0; Q96DL0; Q9Y2V1"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"153.1"	"74.3"	"137.2"	"120.4"	"153.6"	"158.5"	"110.8"	"173.0"	"127.6"	"271.1"	"471.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y2X0"	"Mediator of RNA polymerase II transcription subunit 16 OS=Homo sapiens OX=9606 GN=MED16 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"877"	"96.7"	"7.37"	""	"2.40"	""	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf11635"	"10025"	"ENSG00000175221"	"MED16"	"hsa:10025; Q6PJT2; Q96AD4; Q96I35; Q9Y2X0; Q9Y652"	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; Generic Transcription Pathway"	""	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q06481"	"Amyloid-like protein 2 OS=Homo sapiens OX=9606 GN=APLP2 PE=1 SV=2"	"0.001"	""	"2"	"1"	"2"	"1"	"763"	"86.9"	"4.79"	"257.86"	"2.40"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00014, Pf02177, Pf10515, Pf12924, Pf12925"	"334"	"ENSG00000084234"	"APLP2"	"B3KXX9; H7BXI4; hsa:334; Q06481; Q13861; Q14594; Q14662; Q71U10; Q7M4L3; Q9BT36"	"Platelet degranulation ; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation"	"Splicing factor NOVA regulated synaptic proteins"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62328"	"Thymosin beta-4 OS=Homo sapiens OX=9606 GN=TMSB4X PE=1 SV=2"	"0.000"	""	"16"	"1"	"2"	"1"	"44"	"5.1"	"5.06"	"313.01"	"2.40"	"1"	"1"	"cell organization and biogenesis;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01290"	"7114"	"ENSG00000205542"	"TMSB4X"	"hsa:7114; P01253; P01254; P62328; Q546P5; Q63576; Q9UE55"	"Platelet degranulation"	"Genes targeted by miRNAs in adipocytes; VEGFA-VEGFR2 signaling; IL-18 signaling pathway; Regulation of actin cytoskeleton"	"5"	"0"	"283.5"	"68.9"	"138.4"	"66.4"	"150.0"	"104.4"	"142.2"	"133.9"	"181.9"	"229.8"	"469.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P38117"	"Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3"	"0.001"	""	"5"	"1"	"2"	"1"	"255"	"27.8"	"8.10"	"275.17"	"2.40"	"1"	"1"	"other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf01012"	"2109"	"ENSG00000105379"	"ETFB"	"A8K766; B3KNY2; hsa:2109; P38117; Q6IBH7; Q71RF6; Q9Y3S7"	"Respiratory electron transport; Protein methylation"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q969E8"	"Pre-rRNA-processing protein TSR2 homolog OS=Homo sapiens OX=9606 GN=TSR2 PE=1 SV=1"	"0.001"	""	"4"	"1"	"2"	"1"	"191"	"20.9"	"4.39"	"288.07"	"2.40"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf10273"	"90121"	"ENSG00000158526"	"TSR2"	"hsa:90121; Q969E8"	""	""	"0"	"0"	"86.7"	"44.5"	"85.1"	"83.9"	"82.0"	"104.3"	"76.8"	"91.3"	"73.7"	"116.7"	"190.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43617"	"Trafficking protein particle complex subunit 3 OS=Homo sapiens OX=9606 GN=TRAPPC3 PE=1 SV=1"	"0.001"	""	"4"	"1"	"2"	"1"	"180"	"20.3"	"4.96"	"284.26"	"2.39"	"1"	"1"	"cell organization and biogenesis;transport"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf04051"	"27095"	"ENSG00000054116"	"TRAPPC3"	"A6NDN0; B2RDN2; D3DPS2; hsa:27095; O43617"	"RAB GEFs exchange GTP for GDP on RABs; COPII-mediated vesicle transport"	""	"2"	"0"	"47.4"	"26.0"	"44.5"	"41.3"	"47.7"	"53.6"	"42.8"	"60.0"	"44.5"	"110.1"	"288.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6I9Y2"	"THO complex subunit 7 homolog OS=Homo sapiens OX=9606 GN=THOC7 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"204"	"23.7"	"5.67"	"311.75"	"2.39"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf05615"	"80145"	"ENSG00000163634"	"THOC7"	"hsa:80145; Q6I9Y2; Q6P1L3; Q8WUF2; Q9H5H0"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	""	"3"	"0"	"400.8"	"125.6"	"291.2"	"216.1"	"271.9"	"313.6"	"224.1"	"298.5"	"234.8"	"480.5"	"777.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q03188"	"Centromere protein C OS=Homo sapiens OX=9606 GN=CENPC PE=1 SV=2"	"0.001"	""	"1"	"1"	"2"	"1"	"943"	"106.8"	"9.39"	"244.48"	"2.39"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf11699, Pf15620, Pf15622"	"1060"	"ENSG00000145241"	"CENPC"	"hsa:1060; Q03188; Q6PIR0; Q8IW27; Q9P0M5"	"Separation of Sister Chromatids; Deposition of new CENPA-containing nucleosomes at the centromere; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	""	"7"	"0"	"11.6"	"2.3"	"9.2"	"8.8"	"7.4"	"10.1"	"6.7"	"9.6"	"4.4"	"14.8"	"31.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IVS2"	"Malonyl-CoA-acyl carrier protein transacylase, mitochondrial OS=Homo sapiens OX=9606 GN=MCAT PE=1 SV=2"	"0.001"	""	"2"	"1"	"2"	"1"	"390"	"42.9"	"8.72"	"283.11"	"2.39"	"1"	"1"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00698"	"27349"	"ENSG00000100294"	"MCAT"	"B0QY72; hsa:27349; O95510; O95511; Q8IVS2"	"Mitochondrial Fatty Acid Beta-Oxidation"	"Mitochondrial fatty acid synthesis pathway"	"2"	"0"	"105.9"	"45.5"	"86.2"	"81.6"	"91.2"	"99.5"	"75.0"	"103.5"	"74.5"	"277.5"	"513.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q3ZCQ8"	"Mitochondrial import inner membrane translocase subunit TIM50 OS=Homo sapiens OX=9606 GN=TIMM50 PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"353"	"39.6"	"8.37"	""	"2.39"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;signal transduction"	"other membranes;mitochondrion;nucleus"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf03031"	"92609"	"ENSG00000105197"	"TIMM50"	"hsa:92609; Q330K1; Q3ZCQ8; Q6QA00; Q96FJ5; Q96GY2; Q9H370"	"Mitochondrial protein import"	""	"1"	"0"	"70.4"	"25.8"	"57.0"	"47.8"	"59.5"	"59.0"	"45.0"	"50.8"	"45.6"	"98.0"	"160.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62191"	"26S proteasome regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMC1 PE=1 SV=1"	"0.000"	""	"6"	"2"	"3"	"2"	"440"	"49.2"	"6.21"	"732.53"	"2.39"	"2"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf16450, Pf17862"	"5700"	"ENSG00000100764"	"PSMC1"	"B4DR63; hsa:5700; P49014; P62191; Q03527; Q6IAW0; Q6NW36; Q96AZ3"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; N-glycan trimming in the ER and Calnexin/Calreticulin cycle"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"64"	"0"	"132.4"	"56.3"	"108.8"	"94.0"	"120.9"	"114.5"	"80.4"	"116.7"	"83.6"	"186.2"	"320.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BZF9"	"Uveal autoantigen with coiled-coil domains and ankyrin repeats OS=Homo sapiens OX=9606 GN=UACA PE=1 SV=2"	"0.001"	""	"1"	"2"	"2"	"1"	"1416"	"162.4"	"7.03"	"249.58"	"2.39"	"1"	"1"	"other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus"	"cytoskeletal activity"	"Pf12796"	"55075"	"ENSG00000137831"	"UACA"	"G3XAG2; hsa:55075; Q14DD3; Q8N3B8; Q96NH6; Q9BZF9; Q9HCL1; Q9NWC6"	"Regulation of the apoptosome activity; RHOH GTPase cycle"	""	"2"	"0"	"3.7"	"0.0"	"6.2"	"0.0"	"0.0"	"5.7"	"5.8"	"5.7"	"11.2"	"42.6"	"68.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H7D7"	"WD repeat-containing protein 26 OS=Homo sapiens OX=9606 GN=WDR26 PE=1 SV=3"	""	""	"2"	"1"	"1"	"1"	"661"	"72.1"	"6.16"	""	"2.38"	""	"1"	"protein metabolism;other metabolic processes"	"cytosol;mitochondrion;nucleus;other cell component"	""	"Pf00400, Pf17814"	"80232"	"ENSG00000162923"	"WDR26"	"A0MNN3; hsa:80232; Q4G100; Q59EC4; Q5GLZ9; Q86UY4; Q9H3C2; Q9H7D7"	""	"Ciliary landscape"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BY49"	"Peroxisomal trans-2-enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=PECR PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"303"	"32.5"	"8.81"	"367.43"	"2.38"	"1"	"1"	"other metabolic processes"	"other membranes;cytosol;mitochondrion;other cytoplasmic organelle"	"signal transduction activity or receptor binding;other molecular function"	"Pf13561"	"55825"	"ENSG00000115425"	"PECR"	"B2RE42; hsa:55825; Q53TC4; Q6IAK9; Q9BY49; Q9NRD4; Q9NY60; Q9P1A4"	"Peroxisomal protein import; Alpha-oxidation of phytanate"	"Allograft rejection; Fatty acid biosynthesis; Mitochondrial long chain fatty acid beta-oxidation; Mitochondrial fatty acid oxidation disorders"	"6"	"0"	"244.6"	"133.6"	"255.2"	"229.8"	"207.8"	"277.2"	"178.6"	"270.0"	"210.2"	"493.9"	"779.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5TDH0"	"Protein DDI1 homolog 2 OS=Homo sapiens OX=9606 GN=DDI2 PE=1 SV=1"	"0.002"	""	"4"	"1"	"2"	"1"	"399"	"44.5"	"5.05"	"229.66"	"2.38"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00240, Pf09668"	"84301"	"ENSG00000197312"	"DDI2"	"A8KAE1; hsa:84301; Q5TDH0; Q7RTZ0; Q9BRT1"	""	""	"0"	"0"	"17.9"	"10.7"	"16.1"	"8.6"	"13.6"	"16.7"	"11.2"	"11.5"	"14.2"	"36.3"	"68.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14493"	"Histone RNA hairpin-binding protein OS=Homo sapiens OX=9606 GN=SLBP PE=1 SV=1"	"0.001"	""	"3"	"1"	"2"	"1"	"270"	"31.3"	"7.47"	"283.75"	"2.38"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf15247"	"7884"	"ENSG00000163950"	"SLBP"	"B3KRJ5; hsa:7884; Q14493"	"RNA Polymerase II Transcription Termination; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs; Transport of the SLBP Dependant Mature mRNA"	"8p23.1 copy number variation syndrome; 4p16.3 copy number variation"	"5"	"0"	"134.0"	"71.5"	"110.9"	"103.9"	"97.0"	"106.5"	"103.6"	"141.9"	"126.4"	"177.8"	"276.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96D21"	"GTP-binding protein Rhes OS=Homo sapiens OX=9606 GN=RASD2 PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"266"	"30.3"	"8.90"	""	"2.38"	""	"1"	"cell-cell signaling;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00071"	"23551"	"ENSG00000100302"	"RASD2"	"hsa:23551; O95520; Q5THY8; Q96D21"	""	""	"0"	"0"	"57.7"	"25.8"	"55.1"	"38.5"	"55.4"	"56.1"	"43.6"	"74.0"	"62.0"	"217.8"	"422.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UHL0"	"ATP-dependent RNA helicase DDX25 OS=Homo sapiens OX=9606 GN=DDX25 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"483"	"54.7"	"6.28"	"385.94"	"2.38"	"1"	"1"	"other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"29118"	"ENSG00000109832"	"DDX25"	"B2R6Z0; hsa:29118; Q5XVN2; Q86W81; Q8IYP1; Q9UHL0"	""	""	"0"	"0"	"33.9"	"14.4"	"36.2"	"23.7"	"32.1"	"48.0"	"27.3"	"33.6"	"29.7"	"46.7"	"100.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13489"	"Ribonuclease inhibitor OS=Homo sapiens OX=9606 GN=RNH1 PE=1 SV=2"	"0.001"	""	"2"	"1"	"2"	"1"	"461"	"49.9"	"4.82"	"268.29"	"2.38"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf13516, Pf18779"	"6050"	"ENSG00000023191; ENSG00000276230"	"RNH1"	"hsa:6050; P13489; Q8IZK8; Q96FD7; Q9BQ80; Q9UDK6"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51114"	"Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3"	"0.000"	""	"4"	"2"	"3"	"1"	"621"	"69.7"	"6.15"	"843.02"	"2.37"	"2"	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf05641, Pf12235, Pf16096, Pf16097, Pf17904, Pf18336"	"8087"	"ENSG00000114416"	"FXR1"	"A8K9B8; hsa:8087; P51114; Q7Z450; Q8N6R8"	"Signaling by BRAF and RAF1 fusions"	"Bile acids synthesis and enterohepatic circulation"	"2"	"0"	"21.3"	"6.9"	"20.1"	"17.0"	"14.8"	"20.1"	"14.1"	"17.4"	"22.3"	"40.3"	"59.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86T03"	"Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase OS=Homo sapiens OX=9606 GN=PIP4P1 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"277"	"29.5"	"8.91"	"293.07"	"2.37"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf09788"	"90809"	"ENSG00000165782"	"PIP4P1"	"B2RA35; hsa:90809; Q86T03; Q86U09; Q8WUC0; Q9BU67; Q9NSU8"	"PI5P Regulates TP53 Acetylation; Synthesis of PIPs in the nucleus"	""	"2"	"0"	"11.8"	"3.3"	"7.8"	"5.3"	"7.8"	"8.6"	"6.1"	"8.9"	"9.2"	"14.6"	"34.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VZE5"	"N-alpha-acetyltransferase 35, NatC auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA35 PE=1 SV=1"	"0.001"	""	"2"	"1"	"2"	"1"	"725"	"83.6"	"7.05"	"250.16"	"2.36"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	""	"Pf04112"	"60560"	"ENSG00000135040"	"NAA35"	"hsa:60560; Q5VZE5; Q5VZE6; Q9H631; Q9H703"	"Retrograde transport at the Trans-Golgi-Network"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N567"	"Zinc finger CCHC domain-containing protein 9 OS=Homo sapiens OX=9606 GN=ZCCHC9 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"271"	"30.5"	"9.17"	"279.28"	"2.36"	"1"	"1"	""	"nucleus"	"other molecular function"	"Pf00098"	"84240"	"ENSG00000131732"	"ZCCHC9"	"B2RAE7; hsa:84240; Q8N567; Q9H027"	""	""	"0"	"0"	"107.0"	"53.4"	"111.2"	"100.5"	"127.9"	"144.1"	"90.1"	"130.4"	"91.9"	"199.5"	"294.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75152"	"Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3"	"0.001"	""	"1"	"1"	"2"	"1"	"810"	"89.1"	"8.37"	"276.98"	"2.35"	"1"	"1"	"other metabolic processes;transport"	"nucleus"	"other molecular function"	"Pf15663"	"9877"	"ENSG00000058673"	"ZC3H11A"	"hsa:9877; O75152; Q6AHY4; Q6AHY9; Q6AW79; Q6AWA1; Q6PJK4; Q86XZ7"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	""	"3"	"0"	"63.5"	"18.8"	"41.2"	"35.8"	"43.1"	"41.9"	"35.0"	"45.1"	"31.7"	"69.5"	"139.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86WR0"	"Coiled-coil domain-containing protein 25 OS=Homo sapiens OX=9606 GN=CCDC25 PE=1 SV=2"	"0.000"	""	"5"	"1"	"2"	"1"	"208"	"24.5"	"6.80"	"297.43"	"2.35"	"1"	"1"	"other biological processes"	"plasma membrane;other membranes;other cell component"	"nucleic acid binding activity"	"Pf05670"	"55246"	"ENSG00000147419"	"CCDC25"	"hsa:55246; Q0P663; Q86WR0; Q96SI2; Q9NV98"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05023"	"Sodium/potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1"	"0.001"	""	"1"	"1"	"2"	"1"	"1023"	"112.8"	"5.49"	"253.94"	"2.35"	"1"	"1"	"transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cell component"	"transporter activity;other molecular function"	"Pf00122, Pf00689, Pf00690, Pf13246"	"476"	"ENSG00000163399"	"ATP1A1"	"B2RBR6; B7Z2T5; B7Z3U6; F5H3A1; hsa:476; P05023; Q16689; Q6LDM4; Q9UCN1; Q9UJ20; Q9UJ21"	"Potential therapeutics for SARS; Ion homeostasis; Ion transport by P-type ATPases"	"Pre-implantation embryo; Proximal tubule transport; Arsenic metabolism and reactive oxygen species generation"	"6"	"0"	"26.0"	"8.4"	"15.2"	"19.1"	"18.1"	"20.9"	"16.0"	"21.8"	"23.3"	"45.9"	"91.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NR33"	"DNA polymerase epsilon subunit 4 OS=Homo sapiens OX=9606 GN=POLE4 PE=1 SV=2"	"0.001"	""	"18"	"2"	"2"	"2"	"117"	"12.2"	"4.92"	"247.81"	"2.35"	"1"	"1"	"DNA metabolism;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00808"	"56655"	"ENSG00000115350"	"POLE4"	"hsa:56655; Q53TR2; Q9NR33"	"Activation of the pre-replicative complex; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; DNA replication initiation; Gap-filling DNA repair synthesis and ligation in GG-NER"	"Pyrimidine metabolism; Base excision repair; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"16"	"0"	"18.3"	"7.1"	"17.1"	"12.7"	"14.7"	"16.6"	"18.6"	"40.6"	"42.5"	"87.5"	"72.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9P2D0"	"Inhibitor of Bruton tyrosine kinase OS=Homo sapiens OX=9606 GN=IBTK PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"1353"	"150.4"	"7.71"	""	"2.34"	""	"1"	"transport;other biological processes"	"other membranes;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00415, Pf00651, Pf12796"	"25998"	"ENSG00000005700; ENSG00000283068"	"IBTK"	"hsa:25998; Q2QKU2; Q2QKU3; Q2QKU4; Q5TFD7; Q5TFD9; Q8IUQ9; Q8IUY7; Q8TAI4; Q9HBI8; Q9P2D0; Q9Y3T8"	""	"Genetic causes of porto-sinusoidal vascular disease"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BTZ2"	"Dehydrogenase/reductase SDR family member 4 OS=Homo sapiens OX=9606 GN=DHRS4 PE=1 SV=3"	"0.001"	""	"3"	"1"	"2"	"1"	"278"	"29.5"	"8.56"	"288.36"	"2.34"	"1"	"1"	"other metabolic processes;other biological processes"	"other membranes;cytosol;mitochondrion;ER/Golgi;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf13561"	"10901"	"ENSG00000157326; ENSG00000284807"	"DHRS4"	"B2RB10; B7WNS9; D3YTB8; E2QRL8; hsa:10901; O95162; Q20CR0; Q2LC19; Q2LE81; Q58IU4; Q6E0Y1; Q6UWU3; Q71UQ6; Q8TD03; Q9BTZ2; Q9H3N5; Q9NV08"	"Peroxisomal protein import; RA biosynthesis pathway"	""	"2"	"0"	"56.8"	"25.1"	"55.0"	"45.2"	"63.2"	"76.7"	"48.1"	"71.2"	"49.1"	"127.6"	"232.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9C0D5"	"Protein TANC1 OS=Homo sapiens OX=9606 GN=TANC1 PE=1 SV=3"	"0.001"	""	"0"	"1"	"2"	"1"	"1861"	"202.1"	"8.32"	"250.54"	"2.34"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"other cell component"	""	"Pf00023, Pf12796"	"85461"	"ENSG00000115183"	"TANC1"	"C9JD88; hsa:85461; Q49AI8; Q9C0D5"	""	""	"0"	"0"	"76.1"	"29.6"	"88.0"	"78.7"	"79.4"	"99.7"	"56.9"	"84.8"	"55.3"	"234.5"	"492.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96FF9"	"Sororin OS=Homo sapiens OX=9606 GN=CDCA5 PE=1 SV=1"	"0.001"	""	"3"	"1"	"2"	"1"	"252"	"27.6"	"9.61"	"285.47"	"2.34"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf09666"	"113130"	"ENSG00000146670"	"CDCA5"	"A8K625; hsa:113130; Q96FF9"	"Resolution of Sister Chromatid Cohesion; Separation of Sister Chromatids; Establishment of Sister Chromatid Cohesion"	""	"3"	"0"	"195.6"	"92.7"	"183.1"	"154.7"	"190.3"	"204.3"	"139.5"	"205.0"	"128.4"	"245.3"	"363.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UNF0"	"Protein kinase C and casein kinase substrate in neurons protein 2 OS=Homo sapiens OX=9606 GN=PACSIN2 PE=1 SV=2"	"0.001"	""	"2"	"1"	"2"	"1"	"486"	"55.7"	"5.20"	"265.20"	"2.34"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00018, Pf00611"	"11252"	"ENSG00000100266"	"PACSIN2"	"hsa:11252; O95921; Q96HV9; Q9H0D3; Q9NPN1; Q9UNF0; Q9Y4V2"	"Clathrin-mediated endocytosis"	""	"1"	"0"	"165.4"	"63.5"	"118.3"	"93.9"	"114.0"	"123.0"	"105.4"	"128.4"	"133.3"	"278.9"	"510.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NRG9"	"Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"546"	"59.5"	"7.50"	"305.08"	"2.33"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus"	""	"Pf00400"	"8086"	"ENSG00000094914"	"AAAS"	"hsa:8086; Q5JB47; Q9NRG9; Q9NWI6; Q9UG19"	"RHOA GTPase cycle; HCMV Early Events; ISG15 antiviral mechanism; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; tRNA processing in the nucleus; SUMOylation of chromatin organization proteins; Transport of Mature mRNA derived from an Intron-Containing Transcript; HCMV Late Events; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"	""	"29"	"0"	"66.7"	"16.9"	"51.2"	"42.4"	"48.4"	"61.3"	"45.9"	"65.3"	"47.8"	"75.4"	"233.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q12846"	"Syntaxin-4 OS=Homo sapiens OX=9606 GN=STX4 PE=1 SV=2"	""	""	"4"	"1"	"1"	"1"	"297"	"34.2"	"6.28"	""	"2.33"	""	"1"	"cell organization and biogenesis;stress response;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00804, Pf05739"	"6810"	"ENSG00000103496"	"STX4"	"A8MXY0; hsa:6810; Q12846; Q15525; Q6FHE8"	"ER-Phagosome pathway; Translocation of SLC2A4 (GLUT4) to the plasma membrane; trans-Golgi Network Vesicle Budding; Disinhibition of SNARE formation; Other interleukin signaling"	"Insulin signaling"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BPZ3"	"Polyadenylate-binding protein-interacting protein 2 OS=Homo sapiens OX=9606 GN=PAIP2 PE=1 SV=1"	"0.001"	""	"6"	"1"	"2"	"1"	"127"	"15.0"	"4.12"	"273.29"	"2.33"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf07145"	"51247"	"ENSG00000120727"	"PAIP2"	"B2RBI1; D3DQC6; hsa:51247; Q49A06; Q9BPZ3; Q9H0Y5; Q9P0Q8"	""	""	"0"	"0"	"162.1"	"81.5"	"159.7"	"155.4"	"167.3"	"188.6"	"139.7"	"190.9"	"130.2"	"267.1"	"452.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O95425"	"Supervillin OS=Homo sapiens OX=9606 GN=SVIL PE=1 SV=2"	""	""	"0"	"1"	"1"	"1"	"2214"	"247.6"	"6.98"	""	"2.33"	""	"1"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00626, Pf02209"	"6840"	"ENSG00000197321"	"SVIL"	"D3DRW9; hsa:6840; M1J557; O60611; O60612; O95425; Q5VZK5; Q5VZK6; Q9H1R7"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O94913"	"Pre-mRNA cleavage complex 2 protein Pcf11 OS=Homo sapiens OX=9606 GN=PCF11 PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"1555"	"172.9"	"8.48"	""	"2.32"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04818"	"51585"	"ENSG00000165494"	"PCF11"	"A6H8W7; hsa:51585; O43671; O94913; Q6P0X8"	"RNA polymerase II transcribes snRNA genes; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	""	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92575"	"UBX domain-containing protein 4 OS=Homo sapiens OX=9606 GN=UBXN4 PE=1 SV=2"	"0.001"	""	"1"	"1"	"2"	"1"	"508"	"56.7"	"6.38"	"267.22"	"2.32"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"other membranes;cytosol;ER/Golgi;nucleus"	""	"Pf00789"	"23190"	"ENSG00000144224"	"UBXN4"	"A8K9W4; hsa:23190; Q4ZG56; Q8IYM5; Q92575"	""	""	"0"	"0"	"64.8"	"23.0"	"28.7"	"31.1"	"34.2"	"44.4"	"33.3"	"37.5"	"43.7"	"71.2"	"119.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61927"	"60S ribosomal protein L37 OS=Homo sapiens OX=9606 GN=RPL37 PE=1 SV=2"	"0.001"	""	"6"	"1"	"2"	"1"	"97"	"11.1"	"11.74"	"232.95"	"2.31"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf01907"	"6167"	"ENSG00000145592"	"RPL37"	"B2R4H2; hsa:6167; P02403; P61927; Q6IBB4; Q99883"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"630.3"	"240.1"	"556.3"	"468.3"	"487.2"	"649.1"	"471.9"	"649.5"	"438.2"	"709.9"	"900.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P07384"	"Calpain-1 catalytic subunit OS=Homo sapiens OX=9606 GN=CAPN1 PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"714"	"81.8"	"5.67"	""	"2.31"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00648, Pf01067, Pf13833"	"823"	"ENSG00000014216"	"CAPN1"	"hsa:823; P07384; Q2TTR0; Q6DHV4"	"Formation of the cornified envelope; Degradation of the extracellular matrix; Neutrophil degranulation; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"	"Integrin-mediated cell adhesion; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"7"	"0"	"9.2"	"3.8"	"8.5"	"5.2"	"12.6"	"10.1"	"6.3"	"9.9"	"11.3"	"18.4"	"34.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2L9"	"Leucine-rich repeat and calponin homology domain-containing protein 1 OS=Homo sapiens OX=9606 GN=LRCH1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"728"	"80.8"	"5.94"	"307.25"	"2.31"	"1"	"1"	"other biological processes"	"other cell component"	""	"Pf00307, Pf13855"	"23143"	"ENSG00000136141"	"LRCH1"	"B7ZLL5; F8W6F0; hsa:23143; Q17R43; Q2KHR1; Q5TBU9; Q7Z5F6; Q7Z5F7; Q9Y2L9"	""	""	"0"	"0"	"21.1"	"9.4"	"18.1"	"12.9"	"22.2"	"27.7"	"22.9"	"37.8"	"42.3"	"97.2"	"206.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15439"	"Multidrug resistance-associated protein 4 OS=Homo sapiens OX=9606 GN=ABCC4 PE=1 SV=3"	"0.001"	""	"1"	"1"	"2"	"1"	"1325"	"149.4"	"8.19"	"291.67"	"2.31"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport"	"plasma membrane;other membranes;ER/Golgi;nucleus"	"transporter activity;other molecular function"	"Pf00005, Pf00664"	"10257"	"ENSG00000125257"	"ABCC4"	"A9Z1Z7; B7Z3Q7; hsa:10257; O15439; Q8IVZ4; Q8IZN6; Q8NEW8; Q9Y6J2"	"ABC-family proteins mediated transport; Paracetamol ADME; Platelet degranulation ; Azathioprine ADME"	"Fluoropyrimidine activity; Androgen receptor network in prostate cancer; Drug induction of bile acid pathway; Ectoderm differentiation; Pregnane X receptor pathway; Nuclear receptors meta-pathway; NRF2 pathway; Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling; TYROBP causal network in microglia; Aspirin and miRNAs; Proximal tubule transport; FOXA2 pathway; Prostaglandin synthesis and regulation"	"17"	"0"	"11.1"	"0.0"	"3.2"	"3.8"	"6.2"	"7.9"	"6.7"	"8.4"	"7.4"	"20.7"	"67.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8N6N3"	"UPF0690 protein C1orf52 OS=Homo sapiens OX=9606 GN=C1orf52 PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"182"	"20.6"	"5.21"	""	"2.31"	""	"1"	""	"nucleus"	""	"Pf15559"	"148423"	"ENSG00000162642"	"C1orf52"	"B3KX89; hsa:148423; Q8N6N3; Q8TDK5; Q8TDK6"	""	""	"0"	"0"	"146.1"	"75.2"	"119.2"	"141.0"	"138.8"	"150.9"	"138.0"	"212.5"	"191.1"	"211.7"	"318.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9BY42"	"Replication termination factor 2 OS=Homo sapiens OX=9606 GN=RTF2 PE=1 SV=3"	""	""	"3"	"1"	"1"	"1"	"306"	"33.9"	"8.59"	""	"2.31"	""	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf04641"	"51507"	"ENSG00000022277"	"RTF2"	"E1P5Z9; hsa:51507; Q9BY42; Q9BYL7; Q9HCV9; Q9NX29; Q9NZZ8; Q9P002; Q9UHW3"	""	""	"0"	"0"	"8.4"	"2.4"	"0.0"	"2.7"	"2.8"	"2.7"	"0.0"	"3.4"	"5.3"	"28.0"	"82.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q92785"	"Zinc finger protein ubi-d4 OS=Homo sapiens OX=9606 GN=DPF2 PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"391"	"44.1"	"6.33"	""	"2.30"	""	"1"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00628, Pf14051"	"5977"	"ENSG00000133884"	"DPF2"	"A8K7C9; B4DT58; hsa:5977; Q92785"	""	"Tumor suppressor activity of SMARCB1"	"1"	"0"	"67.9"	"28.9"	"63.6"	"59.1"	"66.4"	"59.7"	"50.3"	"65.1"	"57.4"	"111.6"	"322.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P02671"	"Fibrinogen alpha chain OS=Homo sapiens OX=9606 GN=FGA PE=1 SV=2"	"0.001"	""	"1"	"1"	"2"	"1"	"866"	"94.9"	"6.01"	"244.62"	"2.30"	"1"	"1"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00147, Pf08702, Pf12160"	"2243"	"ENSG00000171560"	"FGA"	"A8K3E4; D3DP14; D3DP15; hsa:2243; P02671; Q4QQH7; Q9BX62; Q9UCH2"	"Amyloid fiber formation; ER-Phagosome pathway; Integrin cell surface interactions; Platelet degranulation ; Signaling by BRAF and RAF1 fusions; MyD88:MAL(TIRAP) cascade initiated on plasma membrane; MyD88 deficiency (TLR2/4); IRAK4 deficiency (TLR2/4); Regulation of TLR by endogenous ligand; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; Common Pathway of Fibrin Clot Formation; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; GRB2:SOS provides linkage to MAPK signaling for Integrins ; p130Cas linkage to MAPK signaling for integrins"	"Selenium micronutrient network; Folate metabolism; Blood clotting cascade; Complement system; VEGFA-VEGFR2 signaling; Fibrin complement receptor 3 signaling pathway; COVID-19, thrombosis and anticoagulation; Network map of SARS-CoV-2 signaling pathway"	"29"	"0"	"353.6"	"112.8"	"311.3"	"248.1"	"255.7"	"330.3"	"202.8"	"298.1"	"174.9"	"393.5"	"513.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08195"	"4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3"	"0.001"	""	"2"	"1"	"2"	"1"	"630"	"68.0"	"5.01"	"244.18"	"2.30"	"1"	"1"	"other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;nucleus;other cytoplasmic organelle;other cell component"	"transporter activity;nucleic acid binding activity"	"Pf00128, Pf16028"	"6520"	"ENSG00000168003"	"SLC3A2"	"hsa:6520; J3KPF3; P08195; Q13543"	"Tryptophan catabolism; Basigin interactions; Amino acid transport across the plasma membrane; Defective SLC7A7 causes lysinuric protein intolerance (LPI)"	"mRNA, protein, and metabolite inducation pathway by cyclosporin A; Ferroptosis; Proximal tubule transport; Pleural mesothelioma"	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99661"	"Kinesin-like protein KIF2C OS=Homo sapiens OX=9606 GN=KIF2C PE=1 SV=2"	"0.001"	""	"1"	"1"	"2"	"1"	"725"	"81.3"	"7.83"	"234.75"	"2.30"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00225"	"11004"	"ENSG00000142945"	"KIF2C"	"B3ITR9; hsa:11004; Q5JR88; Q6ICU1; Q96C18; Q96HB8; Q99661; Q9BWV8"	"RHO GTPases Activate Formins; Separation of Sister Chromatids; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; COPI-dependent Golgi-to-ER retrograde traffic; Kinesins"	"Microtubule cytoskeleton regulation"	"10"	"0"	"12.8"	"9.9"	"13.5"	"11.0"	"14.4"	"11.3"	"9.0"	"12.3"	"9.8"	"23.7"	"43.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92572"	"AP-3 complex subunit sigma-1 OS=Homo sapiens OX=9606 GN=AP3S1 PE=1 SV=1"	"0.001"	""	"5"	"1"	"2"	"1"	"193"	"21.7"	"5.39"	"255.12"	"2.30"	"1"	"1"	"cell organization and biogenesis;transport;signal transduction"	"other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf01217"	"1176"	"ENSG00000177879"	"AP3S1"	"hsa:1176; O00647; O00676; O00721; O00727; Q53XL4; Q6ICQ2; Q92572"	"Golgi Associated Vesicle Biogenesis"	""	"1"	"0"	"109.1"	"48.5"	"111.0"	"87.5"	"107.5"	"91.7"	"75.2"	"119.5"	"106.8"	"254.1"	"442.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BWD1"	"Acetyl-CoA acetyltransferase, cytosolic OS=Homo sapiens OX=9606 GN=ACAT2 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"397"	"41.3"	"6.92"	"342.62"	"2.30"	"1"	"1"	"other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00108, Pf02803"	"39"	"ENSG00000120437"	"ACAT2"	"B7Z233; E1P5B1; hsa:39; Q16146; Q5TCL7; Q8TDM4; Q9BWD1"	"Cholesterol biosynthesis"	"Mevalonate pathway; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Cholesterol metabolism; Cholesterol biosynthesis pathway in hepatocytes; Enterocyte cholesterol metabolism"	"6"	"0"	"31.8"	"10.3"	"15.8"	"7.7"	"14.3"	"9.8"	"13.3"	"12.8"	"18.7"	"24.7"	"47.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VWN6"	"Protein TASOR 2 OS=Homo sapiens OX=9606 GN=TASOR2 PE=1 SV=1"	"0.000"	""	"0"	"2"	"4"	"1"	"2430"	"268.7"	"5.90"	"481.22"	"2.29"	"2"	"1"	"cell organization and biogenesis"	"cytosol;nucleus"	""	"Pf12480, Pf12509"	"54906"	"ENSG00000108021"	"TASOR2"	"hsa:54906; Q2YD91; Q5VWN5; Q5VWN6; Q6ZRQ8; Q8IVG4; Q9BUZ7; Q9H5J9; Q9H7A4; Q9H996; Q9NXA1"	""	""	"0"	"0"	"109.4"	"46.1"	"80.6"	"72.7"	"86.2"	"103.6"	"76.9"	"152.2"	"216.4"	"1021.6"	"1890.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H871"	"E3 ubiquitin-protein transferase RMND5A OS=Homo sapiens OX=9606 GN=RMND5A PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"391"	"44.0"	"6.06"	""	"2.29"	""	"1"	"protein metabolism;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf10607, Pf13445"	"64795"	"ENSG00000153561"	"RMND5A"	"D6W5M6; hsa:64795; Q6NTF0; Q9H6W5; Q9H871; Q9H9H2"	""	"Ciliary landscape"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75694"	"Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1"	"0.000"	""	"1"	"2"	"3"	"2"	"1391"	"155.1"	"6.16"	"464.19"	"2.29"	"2"	"1"	"cell-cell signaling;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;nucleus"	"other molecular function"	"Pf03177, Pf08801"	"9631"	"ENSG00000113569"	"NUP155"	"hsa:9631; O75694; Q9UBE9; Q9UFL5"	"HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Postmitotic nuclear pore complex (NPC) reformation"	""	"29"	"0"	"647.8"	"239.2"	"491.3"	"412.8"	"492.5"	"528.2"	"386.7"	"523.8"	"444.8"	"646.4"	"1176.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IWJ2"	"GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4"	"0.000"	""	"0"	"1"	"2"	"1"	"1684"	"195.8"	"5.14"	"316.21"	"2.28"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;ER/Golgi;nucleus"	"other molecular function"	"Pf01465, Pf16704"	"9648"	"ENSG00000135968"	"GCC2"	"A6H8X8; hsa:9648; O15045; Q4ZG46; Q8IWJ2; Q8TDH3; Q9H2G8"	"Signaling by ALK fusions and activated point mutants; Retrograde transport at the Trans-Golgi-Network"	"Deregulation of Rab and Rab effector genes in bladder cancer"	"3"	"0"	"21.9"	"7.1"	"17.2"	"12.8"	"14.1"	"18.6"	"17.1"	"35.9"	"72.1"	"231.9"	"314.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P2I0"	"Cleavage and polyadenylation specificity factor subunit 2 OS=Homo sapiens OX=9606 GN=CPSF2 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"782"	"88.4"	"5.11"	"333.91"	"2.28"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf07521, Pf10996, Pf13299, Pf16661"	"53981"	"ENSG00000165934"	"CPSF2"	"B3KME1; hsa:53981; Q6NSJ1; Q9H3W7; Q9P2I0"	"Transport of Mature mRNA Derived from an Intronless Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"mRNA processing"	"6"	"0"	"57.2"	"30.9"	"50.6"	"40.7"	"52.4"	"55.2"	"37.8"	"58.1"	"48.2"	"125.6"	"236.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15651"	"High mobility group nucleosome-binding domain-containing protein 3 OS=Homo sapiens OX=9606 GN=HMGN3 PE=1 SV=2"	"0.001"	""	"15"	"1"	"2"	"1"	"99"	"10.7"	"9.66"	"266.50"	"2.28"	"1"	"1"	"cell organization and biogenesis"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01101"	"9324"	"ENSG00000118418"	"HMGN3"	"B2RD37; hsa:9324; Q15651; Q5HYD3; Q7RTT0; Q969M5; Q9BZT7"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O75487"	"Glypican-4 OS=Homo sapiens OX=9606 GN=GPC4 PE=1 SV=4"	""	""	"1"	"1"	"1"	"1"	"556"	"62.4"	"6.68"	""	"2.28"	""	"1"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;signal transduction;other biological processes"	"extracellular matrix;plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf01153"	"2239"	"ENSG00000076716"	"GPC4"	"B2R6J7; B4E2C0; hsa:2239; O75487; Q6ZMA6; Q96L43; Q9NU08; Q9UJN1; Q9UPD9"	"A tetrasaccharide linker sequence is required for GAG synthesis; HS-GAG biosynthesis; HS-GAG degradation; Defective B4GALT7 causes EDS, progeroid type; Defective B3GAT3 causes JDSSDHD; Defective EXT2 causes exostoses 2; Defective EXT1 causes exostoses 1, TRPS2 and CHDS; Defective B3GALT6 causes EDSP2 and SEMDJL1; Attachment and Entry; Retinoid metabolism and transport"	"Wnt signaling"	"11"	"0"	"48.6"	"19.0"	"51.0"	"35.8"	"50.5"	"55.5"	"35.6"	"48.0"	"34.1"	"61.2"	"77.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q16527"	"Cysteine and glycine-rich protein 2 OS=Homo sapiens OX=9606 GN=CSRP2 PE=1 SV=3"	""	""	"7"	"1"	"1"	"1"	"193"	"20.9"	"8.62"	""	"2.27"	""	"1"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412"	"1466"	"ENSG00000175183"	"CSRP2"	"hsa:1466; Q16527; Q93030"	""	"Mesodermal commitment pathway; VEGFA-VEGFR2 signaling; H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity"	"3"	"0"	"34.5"	"20.7"	"36.2"	"35.5"	"41.9"	"37.4"	"38.1"	"37.0"	"28.4"	"45.3"	"64.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P16278"	"Beta-galactosidase OS=Homo sapiens OX=9606 GN=GLB1 PE=1 SV=2"	"0.001"	""	"2"	"1"	"2"	"1"	"677"	"76.0"	"6.57"	"286.42"	"2.27"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01301, Pf13364"	"2720"	"ENSG00000170266"	"GLB1"	"B2R7H8; B7Z6B0; hsa:2720; P16278; P16279"	"Neutrophil degranulation; Glycosphingolipid metabolism; HS-GAG degradation; Sialic acid metabolism; Keratan sulfate degradation; Defective NEU1 causes sialidosis; MPS IV - Morquio syndrome B"	"Ectoderm differentiation; Degradation pathway of sphingolipids, including diseases; Ciliary landscape; Glycosaminoglycan degradation; Sphingolipid metabolism in senescence"	"12"	"0"	"13.4"	"5.8"	"11.0"	"9.3"	"10.5"	"14.0"	"12.4"	"15.3"	"8.1"	"13.3"	"18.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q32P41"	"tRNA (guanine(37)-N1)-methyltransferase OS=Homo sapiens OX=9606 GN=TRMT5 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"509"	"58.2"	"8.62"	""	"2.27"	""	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q32MZ4"	"Leucine-rich repeat flightless-interacting protein 1 OS=Homo sapiens OX=9606 GN=LRRFIP1 PE=1 SV=2"	"0.001"	""	"1"	"1"	"2"	"1"	"808"	"89.2"	"4.65"	"248.34"	"2.27"	"1"	"1"	"other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09738"	"9208"	"ENSG00000124831"	"LRRFIP1"	"E9PGZ2; hsa:9208; O75766; O75799; Q32MZ4; Q32MZ5; Q53T49; Q6PKG2; Q9Y607"	"Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease; LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production"	"IL-18 signaling pathway; 2q37 copy number variation syndrome"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P24666"	"Low molecular weight phosphotyrosine protein phosphatase OS=Homo sapiens OX=9606 GN=ACP1 PE=1 SV=3"	"0.001"	""	"6"	"1"	"2"	"1"	"158"	"18.0"	"6.74"	"264.15"	"2.27"	"1"	"1"	"protein metabolism;other metabolic processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf01451"	"52"	"ENSG00000143727"	"ACP1"	"A8K1L9; B5MCC7; hsa:52; P24666; P24667; Q16035; Q16036; Q16725; Q3KQX8; Q53RU0"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"24.8"	"10.6"	"19.7"	"14.2"	"19.5"	"24.2"	"18.4"	"20.3"	"22.2"	"29.9"	"57.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P48201"	"ATP synthase F(0) complex subunit C3, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5MC3 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"142"	"14.7"	"9.45"	"310.37"	"2.26"	"1"	"1"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00137"	"518"	"ENSG00000154518"	"ATP5MC3"	"B2R4Z0; D3DPF0; hsa:518; P48201; Q4ZFX7"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"5"	"0"	"80.7"	"18.4"	"47.9"	"58.1"	"52.0"	"126.6"	"165.9"	"350.4"	"276.5"	"941.2"	"1272.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q6P1L8"	"39S ribosomal protein L14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL14 PE=1 SV=1"	""	""	"6"	"1"	"1"	"1"	"145"	"15.9"	"10.24"	""	"2.26"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00238"	"64928"	"ENSG00000180992"	"MRPL14"	"B2R575; hsa:64928; Q6P1L8; Q96Q72"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"19.4"	"4.7"	"17.2"	"15.7"	"14.4"	"12.5"	"12.5"	"20.6"	"17.6"	"38.1"	"52.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UPN9"	"E3 ubiquitin-protein ligase TRIM33 OS=Homo sapiens OX=9606 GN=TRIM33 PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"1127"	"122.5"	"6.67"	""	"2.26"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00439, Pf00628, Pf00643, Pf13445"	"51592"	"ENSG00000197323"	"TRIM33"	"hsa:51592; O95855; Q5TG72; Q5TG73; Q5TG74; Q9C017; Q9UJ79; Q9UPN9"	"Downregulation of SMAD2/3:SMAD4 transcriptional activity; Germ layer formation at gastrulation"	"Ectoderm differentiation"	"3"	"0"	"12.1"	"5.3"	"9.0"	"7.9"	"14.2"	"9.7"	"10.9"	"14.2"	"8.5"	"17.7"	"36.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62745"	"Rho-related GTP-binding protein RhoB OS=Homo sapiens OX=9606 GN=RHOB PE=1 SV=1"	"0.001"	""	"5"	"1"	"2"	"1"	"196"	"22.1"	"5.24"	"267.68"	"2.26"	"1"	"1"	"cell adhesion;cell cycle OR cell proliferation;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00071"	"388"	"ENSG00000143878"	"RHOB"	"B2R692; hsa:388; P01121; P62745; Q5U0H6; Q7RTN5; Q7RTR9; Q9CUV7"	"RHOB GTPase cycle; RHO GTPases activate CIT; Sema4D induced cell migration and growth-cone collapse; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; G alpha (12/13) signalling events; RHO GTPases Activate Formins; GPVI-mediated activation cascade; RHO GTPases Activate Rhotekin and Rhophilins"	"Androgen receptor signaling pathway; Neural crest differentiation; Spinal cord injury; Ebola virus infection in host; Gastrin signaling pathway"	"14"	"0"	"82.7"	"53.2"	"62.8"	"47.2"	"62.8"	"59.2"	"57.7"	"63.4"	"73.8"	"128.9"	"162.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O14980"	"Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"1071"	"123.3"	"6.06"	""	"2.26"	""	"1"	"other metabolic processes;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03810, Pf08389, Pf08767, Pf18777, Pf18784, Pf18787"	"7514"	"ENSG00000082898"	"XPO1"	"A6NL14; A8K1K5; D6W5E2; hsa:7514; O14980; Q63HP8; Q68CP3; Q99433"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; MAPK6/MAPK4 signaling; NPAS4 regulates expression of target genes; Rev-mediated nuclear export of HIV RNA; NEP/NS2 Interacts with the Cellular Export Machinery; Heme signaling; Deactivation of the beta-catenin transactivating complex; Estrogen-dependent nuclear events downstream of ESR-membrane signaling; Downregulation of TGF-beta receptor signaling; HuR (ELAVL1) binds and stabilizes mRNA; Cyclin A/B1/B2 associated events during G2/M transition"	"eIF5A regulation in response to inhibition of the nuclear export system; 22q11.2 copy number variation syndrome"	"18"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q86XR2"	"Protein Niban 3 OS=Homo sapiens OX=9606 GN=NIBAN3 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"697"	"77.4"	"8.63"	""	"2.25"	""	"1"	""	""	""	""	"199786"	"ENSG00000167483"	"NIBAN3"	"B4DNU3; B4DVN7; hsa:199786; Q7Z6H6; Q86XR2; Q86XR3; Q86XR4; Q8TEQ3"	""	""	"0"	"0"	"135.3"	"47.0"	"94.6"	"93.4"	"104.1"	"86.5"	"76.7"	"100.7"	"87.2"	"173.5"	"224.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P83876"	"Thioredoxin-like protein 4A OS=Homo sapiens OX=9606 GN=TXNL4A PE=1 SV=1"	"0.001"	""	"8"	"1"	"2"	"1"	"142"	"16.8"	"5.85"	"275.73"	"2.25"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;cytosol;nucleus"	""	"Pf02966"	"10907"	"ENSG00000141759"	"TXNL4A"	"B2RC18; hsa:10907; O14834; P83876"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"mRNA processing"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9BWT3"	"Poly(A) polymerase gamma OS=Homo sapiens OX=9606 GN=PAPOLG PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"736"	"82.8"	"9.14"	""	"2.25"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01909, Pf04926, Pf04928"	"64895"	"ENSG00000115421"	"PAPOLG"	"B2RBH4; hsa:64895; Q59G05; Q969N1; Q9BWT3; Q9H8L2; Q9HAD0"	""	""	"0"	"0"	"9.4"	"6.4"	"8.3"	"7.7"	"7.3"	"10.9"	"7.2"	"12.8"	"12.9"	"57.0"	"160.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q5PSV4"	"Breast cancer metastasis-suppressor 1-like protein OS=Homo sapiens OX=9606 GN=BRMS1L PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"323"	"37.6"	"5.15"	""	"2.25"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf08598"	"84312"	"ENSG00000100916"	"BRMS1L"	"A6NFW5; A6NH45; B2RD65; hsa:84312; Q5PSV4; Q9BRI4"	""	""	"0"	"0"	"252.5"	"107.1"	"190.8"	"154.3"	"182.4"	"201.6"	"153.0"	"207.5"	"197.0"	"438.5"	"656.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y680"	"Peptidyl-prolyl cis-trans isomerase FKBP7 OS=Homo sapiens OX=9606 GN=FKBP7 PE=1 SV=2"	"0.001"	""	"5"	"1"	"2"	"1"	"222"	"25.8"	"6.32"	"265.97"	"2.24"	"1"	"1"	"protein metabolism;other metabolic processes"	"ER/Golgi"	"other molecular function"	"Pf00254, Pf13202"	"51661"	"ENSG00000079150"	"FKBP7"	"hsa:51661; Q4ZG70; Q6V3B2; Q86U65; Q96DA4; Q9Y680; Q9Y6B0"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86WG5"	"Myotubularin-related protein 13 OS=Homo sapiens OX=9606 GN=SBF2 PE=1 SV=1"	"0.000"	""	"1"	"2"	"3"	"1"	"1849"	"208.3"	"7.06"	"525.90"	"2.24"	"2"	"1"	"other metabolic processes;developmental processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf02141, Pf02893, Pf03456, Pf06602, Pf12335"	"81846"	"ENSG00000133812"	"SBF2"	"hsa:81846; Q3MJF0; Q68DQ3; Q6P459; Q6PJD1; Q7Z325; Q7Z621; Q86VE2; Q86WG5; Q96FE2; Q9C097"	"RAB GEFs exchange GTP for GDP on RABs; Synthesis of PIPs at the plasma membrane"	"Intracellular trafficking proteins involved in CMT neuropathy"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14320"	"Protein FAM50A OS=Homo sapiens OX=9606 GN=FAM50A PE=1 SV=2"	"0.001"	""	"2"	"1"	"2"	"1"	"339"	"40.2"	"6.83"	"288.73"	"2.23"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf04921"	"9130"	"ENSG00000071859"	"FAM50A"	"A8KAQ4; B2R997; hsa:9130; Q14320; Q5HY37; Q6PJH5"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"108.9"	"39.9"	"72.8"	"69.9"	"85.0"	"92.0"	"81.8"	"105.5"	"90.6"	"187.8"	"310.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UJX4"	"Anaphase-promoting complex subunit 5 OS=Homo sapiens OX=9606 GN=ANAPC5 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"755"	"85.0"	"6.87"	""	"2.23"	""	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus"	"other molecular function"	"Pf12862"	"51433"	"ENSG00000089053"	"ANAPC5"	"E9PFB2; hsa:51433; Q8N4H7; Q9BQD4; Q9UJX4"	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A; CDK-mediated phosphorylation and removal of Cdc6; Regulation of APC/C activators between G1/S and early anaphase; Senescence-Associated Secretory Phenotype (SASP); Antigen processing: Ubiquitination & Proteasome degradation; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Separation of Sister Chromatids; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of Cyclin B; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; Phosphorylation of the APC/C; APC-Cdc20 mediated degradation of Nek2A; Transcriptional Regulation by VENTX; Aberrant regulation of mitotic exit in cancer due to RB1 defects"	"Cell cycle"	"19"	"0"	"182.4"	"63.5"	"173.1"	"156.1"	"159.5"	"193.2"	"102.5"	"152.5"	"107.5"	"248.3"	"377.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15182"	"Centrin-3 OS=Homo sapiens OX=9606 GN=CETN3 PE=1 SV=2"	"0.000"	""	"5"	"1"	"2"	"1"	"167"	"19.5"	"4.74"	"426.31"	"2.23"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf13499"	"1070"	"ENSG00000153140"	"CETN3"	"hsa:1070; O15182; Q53YD2; Q9BS23"	""	"Breast cancer pathway"	"1"	"0"	"53.4"	"22.5"	"47.8"	"39.9"	"55.3"	"63.4"	"68.2"	"160.3"	"128.4"	"417.2"	"900.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8WV22"	"Non-structural maintenance of chromosomes element 1 homolog OS=Homo sapiens OX=9606 GN=NSMCE1 PE=1 SV=5"	""	""	"2"	"1"	"1"	"1"	"266"	"30.8"	"7.47"	""	"2.22"	""	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf07574, Pf08746"	"197370"	"ENSG00000169189"	"NSMCE1"	"D3DWF6; hsa:197370; Q8WV22; Q9P045; Q9P049"	"SUMOylation of DNA damage response and repair proteins"	""	"1"	"0"	"108.9"	"48.0"	"97.8"	"97.6"	"100.6"	"118.4"	"77.3"	"114.0"	"80.5"	"301.1"	"752.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IXM3"	"39S ribosomal protein L41, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL41 PE=1 SV=1"	"0.001"	""	"12"	"2"	"2"	"2"	"137"	"15.4"	"9.57"	"273.34"	"2.22"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus;other cell component"	"other molecular function"	"Pf09809"	"64975"	"ENSG00000182154"	"MRPL41"	"hsa:64975; Q8IXM3; Q96Q49"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"139.4"	"56.0"	"112.7"	"98.5"	"109.3"	"130.1"	"98.2"	"126.7"	"109.0"	"199.0"	"273.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EY4"	"Translation machinery-associated protein 16 OS=Homo sapiens OX=9606 GN=TMA16 PE=1 SV=2"	"0.000"	""	"5"	"1"	"3"	"1"	"203"	"23.8"	"9.26"	"505.91"	"2.22"	"1"	"1"	"other biological processes"	"nucleus"	"other molecular function"	"Pf11176"	"55319"	"ENSG00000198498"	"TMA16"	"hsa:55319; Q0P6E4; Q0P6J1; Q96EY4; Q9NUR7"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P0U1"	"Mitochondrial import receptor subunit TOM7 homolog OS=Homo sapiens OX=9606 GN=TOMM7 PE=1 SV=1"	"0.001"	""	"11"	"1"	"2"	"1"	"55"	"6.2"	"10.29"	"251.46"	"2.22"	"1"	"1"	"cell organization and biogenesis;stress response;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity"	"Pf08038"	"54543"	"ENSG00000196683"	"TOMM7"	"hsa:54543; O95939; Q9P0U1"	"Mitochondrial protein import; PINK1-PRKN Mediated Mitophagy"	""	"2"	"0"	"119.0"	"37.7"	"82.2"	"70.9"	"108.1"	"107.3"	"118.8"	"106.4"	"93.7"	"188.7"	"262.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A6NC05"	"Glutaredoxin-like protein C5orf63 OS=Homo sapiens OX=9606 GN=C5orf63 PE=2 SV=3"	"0.001"	""	"8"	"1"	"2"	"1"	"138"	"15.8"	"9.06"	"256.01"	"2.22"	"1"	"1"	""	""	""	""	"401207"	"ENSG00000164241"	"C5orf63"	"A6NC05; G3V557; hsa:401207"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VIR6"	"Vacuolar protein sorting-associated protein 53 homolog OS=Homo sapiens OX=9606 GN=VPS53 PE=1 SV=1"	"0.001"	""	"1"	"1"	"2"	"1"	"699"	"79.6"	"6.02"	"235.63"	"2.21"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"21.1"	"10.9"	"18.1"	"20.9"	"20.7"	"26.4"	"17.1"	"21.2"	"24.1"	"77.0"	"176.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P40938"	"Replication factor C subunit 3 OS=Homo sapiens OX=9606 GN=RFC3 PE=1 SV=2"	"0.001"	""	"3"	"1"	"2"	"1"	"356"	"40.5"	"8.34"	"247.90"	"2.21"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13177"	"5983"	"ENSG00000133119"	"RFC3"	"C9JU95; hsa:5983; O15252; P40938; Q5W0E8"	"PCNA-Dependent Long Patch Base Excision Repair; Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; Recognition of DNA damage by PCNA-containing replication complex; Dual Incision in GG-NER; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER; Polymerase switching on the C-strand of the telomere; Polymerase switching"	"Gastric cancer network 2; Retinoblastoma gene in cancer; DNA replication; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"28"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P04114"	"Apolipoprotein B-100 OS=Homo sapiens OX=9606 GN=APOB PE=1 SV=2"	""	""	"0"	"1"	"1"	"1"	"4563"	"515.3"	"7.05"	""	"2.21"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;transporter activity;other molecular function"	"Pf01347, Pf06448, Pf09172, Pf12491"	"338"	"ENSG00000084674"	"APOB"	"hsa:338; O00502; P04114; P78479; P78480; P78481; Q13779; Q13785; Q13786; Q13787; Q13788; Q4ZG63; Q53QC8; Q7Z600; Q9UMN0"	"Cell surface interactions at the vascular wall; Scavenging by Class B Receptors; Regulation of TLR by endogenous ligand; Heme signaling; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Retinoid metabolism and transport; Cargo recognition for clathrin-mediated endocytosis; LDL clearance; Chylomicron clearance; Scavenging by Class A Receptors; Chylomicron assembly; Chylomicron remodeling; VLDL assembly; VLDL clearance; Scavenging by Class F Receptors; Scavenging by Class H Receptors; Platelet sensitization by LDL; LDL remodeling"	"Selenium micronutrient network; Vitamin B12 metabolism; Folate metabolism; Statin inhibition of cholesterol production; Male infertility; Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins; Familial hyperlipidemia type 2; Cholesterol metabolism; Female steroid hormones in cardiomyocyte energy metabolism; Fatty Acids and Lipoproteins Transport in Hepatocytes; Enterocyte cholesterol metabolism"	"31"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q86YB8"	"ERO1-like protein beta OS=Homo sapiens OX=9606 GN=ERO1B PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"467"	"53.5"	"7.99"	""	"2.21"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf04137"	"56605"	"ENSG00000086619"	"ERO1B"	"B4DF57; hsa:56605; Q5T1H4; Q86YB8; Q8IZ11; Q9NR62"	"Insulin processing"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WUW1"	"Protein BRICK1 OS=Homo sapiens OX=9606 GN=BRK1 PE=1 SV=1"	"0.001"	""	"9"	"1"	"2"	"1"	"75"	"8.7"	"5.45"	"283.91"	"2.21"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	""	"55845"	"ENSG00000254999"	"BRK1"	"B2R5E2; hsa:55845; Q8WUW1; Q9P082"	"RAC1 GTPase cycle; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; VEGFA-VEGFR2 Pathway; RAC2 GTPase cycle; RAC3 GTPase cycle"	"Regulation of actin cytoskeleton"	"8"	"0"	"169.3"	"62.3"	"159.0"	"157.6"	"174.7"	"230.8"	"172.1"	"280.2"	"207.0"	"609.7"	"1251.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8N960"	"Centrosomal protein of 120 kDa OS=Homo sapiens OX=9606 GN=CEP120 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"986"	"112.6"	"6.25"	""	"2.21"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"cytoskeleton;other cell component"	""	"Pf00168, Pf12416"	"153241"	"ENSG00000168944"	"CEP120"	"hsa:153241; Q6AI52; Q6AW89; Q8IWB5; Q8N960; Q8N9Y0; Q8NDE8"	""	"Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P35398"	"Nuclear receptor ROR-alpha OS=Homo sapiens OX=9606 GN=RORA PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"523"	"58.9"	"6.74"	""	"2.20"	""	"1"	"cell cycle OR cell proliferation;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00104, Pf00105"	"6095"	"ENSG00000069667"	"RORA"	"hsa:6095; P35397; P35398; P35399; P45445; Q495X4; Q96H83"	"Interleukin-4 and Interleukin-13 signaling; PPARA activates gene expression; Heme signaling; Nuclear Receptor transcription pathway; SUMOylation of intracellular receptors; RORA activates gene expression"	"Nuclear receptors; Adipogenesis; Development and heterogeneity of the ILC family; White fat cell differentiation; Th17 cell differentiation pathway; Inflammatory bowel disease signaling; Sudden infant death syndrome (SIDS) susceptibility pathways"	"14"	"0"	"76.2"	"34.2"	"83.2"	"68.9"	"74.2"	"94.3"	"70.0"	"103.9"	"86.1"	"128.3"	"169.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07311"	"Acylphosphatase-1 OS=Homo sapiens OX=9606 GN=ACYP1 PE=1 SV=2"	"0.001"	""	"7"	"1"	"2"	"1"	"99"	"11.3"	"9.31"	"248.53"	"2.20"	"1"	"1"	"other metabolic processes"	""	"other molecular function"	"Pf00708"	"97"	"ENSG00000119640"	"ACYP1"	"A6NDV8; B2R590; hsa:97; P07311"	""	""	"0"	"0"	"80.7"	"40.2"	"86.3"	"67.4"	"80.3"	"98.8"	"68.1"	"114.9"	"92.9"	"277.1"	"1019.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P14735"	"Insulin-degrading enzyme OS=Homo sapiens OX=9606 GN=IDE PE=1 SV=4"	""	""	"1"	"1"	"1"	"1"	"1019"	"117.9"	"6.61"	""	"2.20"	""	"1"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00675, Pf05193, Pf16187"	"3416"	"ENSG00000119912"	"IDE"	"B2R721; B7ZAU2; D3DR35; hsa:3416; P14735; Q5T5N2"	"Ub-specific processing proteases; Peroxisomal protein import; Insulin receptor recycling"	"Alzheimer's disease and miRNA effects; Alzheimer's disease"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15853"	"Upstream stimulatory factor 2 OS=Homo sapiens OX=9606 GN=USF2 PE=1 SV=1"	"0.001"	""	"3"	"1"	"2"	"1"	"346"	"36.9"	"5.10"	"274.60"	"2.20"	"1"	"1"	"transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00010"	"7392"	"ENSG00000105698"	"USF2"	"hsa:7392; O00671; O00709; Q05750; Q07952; Q15851; Q15852; Q15853; Q6FI33; Q6YI47"	"Estrogen-dependent gene expression"	"Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4)"	"2"	"0"	"25.4"	"9.3"	"23.0"	"20.6"	"17.1"	"24.3"	"20.3"	"25.5"	"16.7"	"30.0"	"57.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NRM2"	"Zinc finger protein 277 OS=Homo sapiens OX=9606 GN=ZNF277 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"450"	"52.8"	"5.34"	""	"2.20"	""	"1"	"stress response;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf12756"	"11179"	"ENSG00000198839"	"ZNF277"	"hsa:11179; Q75MZ2; Q75MZ3; Q8WY14; Q9NRM2"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q08AD1"	"Calmodulin-regulated spectrin-associated protein 2 OS=Homo sapiens OX=9606 GN=CAMSAP2 PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"1489"	"168.0"	"6.80"	""	"2.19"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;ER/Golgi"	"cytoskeletal activity;other molecular function"	"Pf08683, Pf11971, Pf17095"	"23271"	"ENSG00000118200"	"CAMSAP2"	"B1APG6; hsa:23271; Q08AD1; Q08AD2; Q6PGN8; Q96FB3; Q9UG20; Q9UPS4"	""	""	"0"	"0"	"31.6"	"10.3"	"26.3"	"28.5"	"57.9"	"29.6"	"24.3"	"42.5"	"52.6"	"262.3"	"276.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23786"	"Carnitine O-palmitoyltransferase 2, mitochondrial OS=Homo sapiens OX=9606 GN=CPT2 PE=1 SV=2"	"0.001"	""	"2"	"1"	"2"	"1"	"658"	"73.7"	"8.18"	"285.39"	"2.19"	"1"	"1"	"other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf00755"	"1376"	"ENSG00000157184"	"CPT2"	"B2R6S0; hsa:1376; P23786; Q5SW68; Q9BQ26"	"PPARA activates gene expression; Carnitine metabolism"	"Fatty acid beta-oxidation; PPAR-alpha pathway; Nuclear receptors meta-pathway; Mitochondrial long chain fatty acid beta-oxidation; PPAR signaling pathway; Thermogenesis; Mitochondrial fatty acid oxidation disorders"	"9"	"0"	"32.0"	"11.9"	"34.4"	"30.4"	"27.9"	"36.8"	"27.7"	"29.4"	"24.4"	"62.2"	"190.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8IYW4"	"ENTH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ENTHD1 PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"607"	"67.5"	"6.62"	""	"2.19"	""	"1"	"transport"	"plasma membrane;other membranes;other cytoplasmic organelle"	"other molecular function"	"Pf01417"	"150350"	"ENSG00000176177"	"ENTHD1"	"B0QYD5; hsa:150350; Q5H9F7; Q8IYW4; Q96LK3"	""	""	"0"	"0"	"19.3"	"6.5"	"18.1"	"11.5"	"13.7"	"20.4"	"18.2"	"23.0"	"30.9"	"384.7"	"586.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P53803"	"DNA-directed RNA polymerases I, II, and III subunit RPABC4 OS=Homo sapiens OX=9606 GN=POLR2K PE=1 SV=1"	""	""	"10"	"1"	"1"	"1"	"58"	"7.0"	"9.06"	""	"2.18"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03604"	"5440"	"ENSG00000147669"	"POLR2K"	"hsa:5440; P53803; Q6IBD4"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; B-WICH complex positively regulates rRNA expression; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; mRNA Splicing - Major Pathway; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"57"	"0"	"65.1"	"24.8"	"69.0"	"64.7"	"62.3"	"73.7"	"48.5"	"91.0"	"168.4"	"542.1"	"762.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H7C9"	"Mth938 domain-containing protein OS=Homo sapiens OX=9606 GN=AAMDC PE=1 SV=1"	"0.001"	""	"7"	"1"	"2"	"1"	"122"	"13.3"	"8.46"	"288.45"	"2.18"	"1"	"1"	"other biological processes"	"other cell component"	""	"Pf04430"	"28971"	"ENSG00000087884"	"AAMDC"	"hsa:28971; Q96AQ4; Q9H7C9; Q9Y6B1"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z4W1"	"L-xylulose reductase OS=Homo sapiens OX=9606 GN=DCXR PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"244"	"25.9"	"8.10"	"278.99"	"2.18"	"1"	"1"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf13561"	"51181"	"ENSG00000169738"	"DCXR"	"hsa:51181; Q7Z4W1; Q9BTZ3; Q9UHY9"	"Formation of xylulose-5-phosphate; Essential pentosuria"	""	"2"	"0"	"201.2"	"71.8"	"168.3"	"130.9"	"148.5"	"159.8"	"126.2"	"151.2"	"128.8"	"203.6"	"359.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q969J3"	"BLOC-1-related complex subunit 5 OS=Homo sapiens OX=9606 GN=BORCS5 PE=1 SV=1"	""	""	"6"	"1"	"1"	"1"	"196"	"22.2"	"6.35"	""	"2.18"	""	"1"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf10158"	"118426"	"ENSG00000165714; ENSG00000280689"	"BORCS5"	"hsa:118426; Q969J3; Q96QS5"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8TER0"	"Sushi, nidogen and EGF-like domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNED1 PE=2 SV=2"	""	""	"1"	"1"	"1"	"1"	"1413"	"152.1"	"6.98"	""	"2.17"	""	"1"	"cell adhesion"	"non-structural extracellular;extracellular matrix"	"signal transduction activity or receptor binding;other molecular function"	"Pf00008, Pf00041, Pf06119, Pf12661"	"25992"	"ENSG00000162804"	"SNED1"	"B5MDC3; B7WNK6; B7WPM0; hsa:25992; Q336F4; Q336F5; Q8N369; Q8TEP7; Q8TER0"	""	"2q37 copy number variation syndrome"	"1"	"0"	"128.8"	"24.6"	"72.3"	"66.4"	"71.3"	"70.2"	"68.1"	"84.2"	"49.2"	"84.8"	"132.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TED0"	"U3 small nucleolar RNA-associated protein 15 homolog OS=Homo sapiens OX=9606 GN=UTP15 PE=1 SV=3"	"0.001"	""	"3"	"1"	"2"	"1"	"518"	"58.4"	"9.11"	"269.19"	"2.17"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"ER/Golgi;nucleus;other cell component"	""	"Pf00400, Pf09384"	"84135"	"ENSG00000164338"	"UTP15"	"B4DU75; B4DXK8; hsa:84135; Q6IA60; Q8TED0; Q96E08; Q9H9F8"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UPW5"	"Cytosolic carboxypeptidase 1 OS=Homo sapiens OX=9606 GN=AGTPBP1 PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"1226"	"138.4"	"6.15"	""	"2.17"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00246, Pf18027"	"23287"	"ENSG00000135049"	"AGTPBP1"	"B4DIT6; B4DRZ8; hsa:23287; Q5VV80; Q63HM7; Q658P5; Q6P9D6; Q9H8U6; Q9H9W8; Q9NVK1; Q9UPW5"	"Carboxyterminal post-translational modifications of tubulin"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8N954"	"G patch domain-containing protein 11 OS=Homo sapiens OX=9606 GN=GPATCH11 PE=1 SV=4"	""	""	"2"	"1"	"1"	"1"	"285"	"33.3"	"5.86"	""	"2.16"	""	"1"	""	"other cell component"	"nucleic acid binding activity"	"Pf01585, Pf13821"	"253635"	""	"GPATCH11"	"A0A0A0MSF9; A8K0D9; B7Z2G4; B8ZZ44; hsa:253635; Q8N954"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60244"	"Mediator of RNA polymerase II transcription subunit 14 OS=Homo sapiens OX=9606 GN=MED14 PE=1 SV=2"	"0.001"	""	"0"	"1"	"2"	"1"	"1454"	"160.5"	"8.73"	"252.99"	"2.16"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf08638"	"9282"	"ENSG00000180182"	"MED14"	"hsa:9282; O60244; Q4KMR7; Q9UNB3"	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; Generic Transcription Pathway"	"Vitamin D in inflammatory diseases"	"4"	"0"	"28.1"	"20.8"	"29.8"	"27.3"	"27.6"	"31.5"	"31.6"	"35.9"	"23.2"	"56.5"	"190.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9P275"	"Ubiquitin carboxyl-terminal hydrolase 36 OS=Homo sapiens OX=9606 GN=USP36 PE=1 SV=4"	""	""	"1"	"1"	"1"	"1"	"1123"	"122.8"	"9.70"	""	"2.16"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00443"	"57602"	"ENSG00000055483"	"USP36"	"hsa:57602; Q05C98; Q05DD0; Q6IQ38; Q8NDM8; Q9NVC8; Q9P275"	""	""	"0"	"0"	"36.8"	"14.0"	"35.5"	"28.9"	"37.4"	"39.0"	"39.8"	"43.8"	"27.3"	"81.0"	"179.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q15058"	"Kinesin-like protein KIF14 OS=Homo sapiens OX=9606 GN=KIF14 PE=1 SV=1"	""	""	"1"	"1"	"1"	"1"	"1648"	"186.4"	"7.91"	""	"2.15"	""	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225, Pf00498, Pf16183"	"9928"	"ENSG00000118193"	"KIF14"	"hsa:9928; Q14CI8; Q15058; Q4G0A5; Q5T1W3"	"RND2 GTPase cycle; RND1 GTPase cycle; RHO GTPases activate CIT"	""	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15942"	"Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1"	"0.001"	""	"1"	"1"	"2"	"1"	"572"	"61.2"	"6.67"	"254.82"	"2.15"	"1"	"1"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00412"	"7791"	"ENSG00000159840; ENSG00000285443"	"ZYX"	"A4D2G6; B4DQX7; hsa:7791; Q15942; Q6I9S4"	""	"Integrin-mediated cell adhesion; Focal adhesion"	"2"	"0"	"124.6"	"59.7"	"129.6"	"117.1"	"133.4"	"140.6"	"91.7"	"120.1"	"97.4"	"183.5"	"322.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NTM9"	"Copper homeostasis protein cutC homolog OS=Homo sapiens OX=9606 GN=CUTC PE=1 SV=1"	"0.001"	""	"2"	"1"	"2"	"1"	"273"	"29.3"	"8.18"	"252.30"	"2.15"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf03932"	"51076"	"ENSG00000119929"	"CUTC"	"hsa:51076; Q5TCZ8; Q9NTM9; Q9Y321"	"Ion transport by P-type ATPases"	""	"1"	"0"	"72.1"	"30.9"	"65.3"	"75.1"	"70.8"	"71.5"	"52.7"	"103.3"	"68.3"	"221.9"	"338.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96RW7"	"Hemicentin-1 OS=Homo sapiens OX=9606 GN=HMCN1 PE=1 SV=2"	""	""	"0"	"1"	"1"	"1"	"5635"	"613.0"	"6.49"	""	"2.15"	""	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"extracellular matrix;plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00090, Pf07474, Pf07645, Pf07679, Pf12662, Pf13927"	"83872"	"ENSG00000143341"	"HMCN1"	"A6NGE3; hsa:83872; Q5TYR7; Q96DN3; Q96DN8; Q96RW7; Q96SC3"	""	""	"0"	"0"	"43.0"	"16.6"	"36.5"	"30.0"	"37.8"	"37.2"	"27.6"	"40.0"	"31.9"	"86.9"	"226.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63165"	"Small ubiquitin-related modifier 1 OS=Homo sapiens OX=9606 GN=SUMO1 PE=1 SV=1"	"0.001"	""	"16"	"2"	"2"	"2"	"101"	"11.6"	"5.52"	"234.64"	"2.15"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf11976"	"7341"	"ENSG00000116030"	"SUMO1"	"A8MUS8; B2R4I5; hsa:7341; P55856; P63165; Q6FGG0; Q6NZ62; Q93068"	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; SUMOylation of intracellular receptors; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; Regulation of IFNG signaling; SUMOylation of transcription factors; Postmitotic nuclear pore complex (NPC) reformation; Formation of Incision Complex in GG-NER; Negative regulation of activity of TFAP2 (AP-2) family transcription factors; Maturation of nucleoprotein; SUMOylation of immune response proteins; SUMOylation of nuclear envelope proteins; Maturation of nucleoprotein; SUMO is conjugated to E1 (UBA2:SAE1); SUMO is transferred from E1 to E2 (UBE2I, UBC9); SUMO is proteolytically processed"	"Androgen receptor signaling pathway; TP53 network; Exercise-induced circadian regulation"	"25"	"0"	"391.6"	"198.5"	"327.9"	"277.5"	"336.4"	"375.5"	"327.0"	"365.3"	"304.5"	"487.6"	"726.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15164"	"Transcription intermediary factor 1-alpha OS=Homo sapiens OX=9606 GN=TRIM24 PE=1 SV=3"	"0.001"	""	"1"	"1"	"2"	"1"	"1050"	"116.8"	"7.11"	"255.85"	"2.15"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;kinase activity;other molecular function"	"Pf00439, Pf00628, Pf00643"	"8805"	"ENSG00000122779"	"TRIM24"	"A4D1R7; A4D1R8; hsa:8805; O15164; O95854"	"Signaling by BRAF and RAF1 fusions; Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease"	""	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P161"	"39S ribosomal protein L54, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL54 PE=1 SV=1"	"0.001"	""	"7"	"1"	"2"	"1"	"138"	"15.8"	"9.60"	"283.66"	"2.14"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf08561"	"116541"	"ENSG00000183617"	"MRPL54"	"hsa:116541; Q6P161"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"133.2"	"60.1"	"111.9"	"84.1"	"110.2"	"108.0"	"84.2"	"98.8"	"88.3"	"149.5"	"266.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15173"	"Membrane-associated progesterone receptor component 2 OS=Homo sapiens OX=9606 GN=PGRMC2 PE=1 SV=1"	"0.001"	""	"3"	"1"	"2"	"1"	"223"	"23.8"	"4.88"	"248.85"	"2.14"	"1"	"1"	"transport;signal transduction;other biological processes"	"ER/Golgi;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00173"	"10424"	"ENSG00000164040"	"PGRMC2"	"hsa:10424; O15173; Q569H1"	"RHOA GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOD GTPase cycle"	"Ciliary landscape"	"6"	"0"	"348.0"	"107.9"	"204.7"	"168.8"	"226.3"	"210.0"	"197.9"	"260.9"	"220.8"	"420.5"	"938.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q14517"	"Protocadherin Fat 1 OS=Homo sapiens OX=9606 GN=FAT1 PE=1 SV=2"	""	""	"0"	"1"	"1"	"1"	"4588"	"506.0"	"5.00"	""	"2.14"	""	"1"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00008, Pf00028, Pf02210"	"2195"	"ENSG00000083857"	"FAT1"	"hsa:2195; Q14517"	""	"Primary focal segmental glomerulosclerosis (FSGS); Head and neck squamous cell carcinoma"	"2"	"0"	"114.8"	"51.6"	"89.3"	"66.7"	"81.3"	"81.4"	"77.6"	"95.8"	"122.2"	"235.5"	"385.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q08378"	"Golgin subfamily A member 3 OS=Homo sapiens OX=9606 GN=GOLGA3 PE=1 SV=2"	"0.001"	""	"1"	"1"	"2"	"1"	"1498"	"167.3"	"5.44"	"234.86"	"2.13"	"1"	"1"	""	"other membranes;cytosol;ER/Golgi;nucleus"	""	""	"2802"	"ENSG00000090615"	"GOLGA3"	"A5PKX6; hsa:2802; O43241; Q08378; Q6P9C7; Q86XW3; Q8TDA9; Q8WZA3"	"RND2 GTPase cycle"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P46108"	"Adapter molecule crk OS=Homo sapiens OX=9606 GN=CRK PE=1 SV=2"	""	""	"4"	"1"	"1"	"1"	"304"	"33.8"	"5.55"	""	"2.13"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00017, Pf00018, Pf07653"	"1398"	"ENSG00000167193"	"CRK"	"A8MWE8; B0LPE8; D3DTH6; hsa:1398; P46108; Q96GA9; Q96HJ0"	"FCGR3A-mediated phagocytosis; Regulation of signaling by CBL; Regulation of actin dynamics for phagocytic cup formation; Downstream signal transduction; VEGFA-VEGFR2 Pathway; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases; ARMS-mediated activation; p130Cas linkage to MAPK signaling for integrins; MET activates RAP1 and RAC1; MET receptor recycling"	"Integrin-mediated cell adhesion; Androgen receptor network in prostate cancer; B cell receptor signaling pathway; Kit receptor signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; RAC1/PAK1/p38/MMP2 pathway; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Chemokine signaling pathway; Rett syndrome causing genes; EGF/EGFR signaling pathway; Gastrin signaling pathway; Insulin signaling; Regulation of actin cytoskeleton; GDNF signaling; Interferon type I signaling pathways; ErbB signaling pathway; T-cell receptor signaling pathway"	"30"	"0"	"79.8"	"51.6"	"76.9"	"71.9"	"73.4"	"69.5"	"64.6"	"72.0"	"82.7"	"124.9"	"209.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NS91"	"E3 ubiquitin-protein ligase RAD18 OS=Homo sapiens OX=9606 GN=RAD18 PE=1 SV=2"	"0.001"	""	"1"	"1"	"2"	"1"	"495"	"56.2"	"7.58"	"256.19"	"2.13"	"1"	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02037, Pf13923"	"56852"	"ENSG00000070950"	"RAD18"	"hsa:56852; Q58F55; Q9NRT6; Q9NS91"	"Recognition of DNA damage by PCNA-containing replication complex; E3 ubiquitin ligases ubiquitinate target proteins"	"SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome"	"3"	"0"	"86.0"	"31.2"	"76.5"	"83.5"	"90.2"	"91.1"	"66.4"	"107.6"	"76.6"	"141.1"	"295.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99426"	"Tubulin-folding cofactor B OS=Homo sapiens OX=9606 GN=TBCB PE=1 SV=2"	"0.000"	""	"7"	"1"	"2"	"1"	"244"	"27.3"	"5.15"	"318.66"	"2.13"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf01302, Pf14560"	"1155"	"ENSG00000105254"	"TBCB"	"hsa:1155; O00111; O00674; O14728; Q6FGY5; Q99426"	"Post-chaperonin tubulin folding pathway"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8TDJ6"	"DmX-like protein 2 OS=Homo sapiens OX=9606 GN=DMXL2 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"3036"	"339.4"	"6.38"	""	"2.13"	""	"1"	"other biological processes"	"other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf00400, Pf12234"	"23312"	"ENSG00000104093"	"DMXL2"	"B2RTR3; B7ZMH3; F5GWF1; hsa:23312; O94938; Q8TDJ6"	""	""	"0"	"0"	"5.2"	"0.0"	"3.2"	"3.4"	"3.8"	"11.8"	"16.5"	"29.1"	"25.0"	"33.5"	"29.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25490"	"Transcriptional repressor protein YY1 OS=Homo sapiens OX=9606 GN=YY1 PE=1 SV=2"	"0.000"	""	"6"	"2"	"3"	"2"	"414"	"44.7"	"6.25"	"699.13"	"2.12"	"2"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00096"	"7528"	"ENSG00000100811"	"YY1"	"hsa:7528; P25490; Q14935"	"UCH proteinases; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; DNA Damage Recognition in GG-NER; TFAP2 (AP-2) family regulates transcription of growth factors and their receptors"	"Sterol regulatory element-binding proteins (SREBP) signaling; Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4); Pleural mesothelioma"	"8"	"0"	"239.1"	"67.0"	"138.8"	"151.1"	"179.6"	"194.0"	"112.8"	"196.0"	"151.5"	"492.3"	"925.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N4Q1"	"Mitochondrial intermembrane space import and assembly protein 40 OS=Homo sapiens OX=9606 GN=CHCHD4 PE=1 SV=1"	"0.001"	""	"4"	"1"	"2"	"1"	"142"	"16.0"	"4.31"	"252.40"	"2.12"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport"	"mitochondrion"	"other molecular function"	"Pf06747"	"131474"	"ENSG00000163528"	"CHCHD4"	"A8K3Z9; hsa:131474; Q8N4Q1; Q96AI2; Q96MY6"	"Mitochondrial protein import"	""	"1"	"0"	"126.5"	"73.9"	"159.9"	"136.3"	"135.1"	"185.4"	"135.1"	"156.2"	"121.9"	"224.7"	"337.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q5VUA4"	"Zinc finger protein 318 OS=Homo sapiens OX=9606 GN=ZNF318 PE=1 SV=2"	""	""	"0"	"1"	"1"	"1"	"2279"	"251.0"	"7.20"	""	"2.12"	""	"1"	"cell cycle OR cell proliferation;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	""	"24149"	"ENSG00000171467"	"ZNF318"	"hsa:24149; O94796; Q4G0E4; Q5VUA4; Q8NEM6; Q9UNU8; Q9Y2W9"	""	"Androgen receptor signaling pathway"	"1"	"0"	"198.5"	"81.4"	"245.9"	"223.8"	"236.1"	"281.6"	"167.2"	"234.5"	"139.4"	"269.6"	"543.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96HJ9"	"Protein FMC1 homolog OS=Homo sapiens OX=9606 GN=FMC1 PE=1 SV=2"	"0.001"	""	"15"	"1"	"2"	"1"	"113"	"12.7"	"10.07"	"235.20"	"2.12"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"mitochondrion"	""	""	"100996928; 154791"	"ENSG00000164898"	"FMC1"	"B7Z4Q3; hsa:100996928; hsa:154791; Q75M90; Q96HJ9; Q9P0B3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51649"	"Succinate-semialdehyde dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH5A1 PE=1 SV=2"	"0.001"	""	"2"	"1"	"2"	"1"	"535"	"57.2"	"8.28"	"284.08"	"2.12"	"1"	"1"	"other metabolic processes;developmental processes"	"mitochondrion"	"other molecular function"	"Pf00171"	"7915"	"ENSG00000112294"	"ALDH5A1"	"B2RD26; G5E949; hsa:7915; P51649; Q546H9; Q8N3W6"	"Degradation of GABA"	"Fragile X syndrome"	"2"	"0"	"11.6"	"3.9"	"7.0"	"5.2"	"11.3"	"13.5"	"9.7"	"11.1"	"11.3"	"20.5"	"78.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O60281"	"Zinc finger protein 292 OS=Homo sapiens OX=9606 GN=ZNF292 PE=1 SV=3"	""	""	"0"	"1"	"1"	"1"	"2723"	"304.6"	"7.39"	""	"2.11"	""	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00096"	"23036"	"ENSG00000188994"	"ZNF292"	"hsa:23036; O60281; Q5W0B2; Q7Z3L7; Q9H8G3; Q9H8J4"	""	""	"0"	"0"	"102.2"	"38.8"	"95.3"	"96.0"	"114.5"	"114.8"	"93.2"	"161.0"	"150.2"	"474.2"	"709.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WTT2"	"Nucleolar complex protein 3 homolog OS=Homo sapiens OX=9606 GN=NOC3L PE=1 SV=1"	"0.001"	""	"1"	"1"	"2"	"1"	"800"	"92.5"	"9.17"	"251.79"	"2.11"	"1"	"1"	"DNA metabolism;other metabolic processes;other biological processes"	"mitochondrion;nucleus"	"other molecular function"	"Pf03914, Pf07540"	"64318"	"ENSG00000173145"	"NOC3L"	"hsa:64318; Q8WTT2; Q9H5M6; Q9H9D8"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O95835"	"Serine/threonine-protein kinase LATS1 OS=Homo sapiens OX=9606 GN=LATS1 PE=1 SV=1"	""	""	"1"	"1"	"1"	"1"	"1130"	"126.8"	"8.70"	""	"2.11"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00627"	"9113"	"ENSG00000131023"	"LATS1"	"hsa:9113; O95835; Q6PKD0"	"Signaling by Hippo"	"Mesodermal commitment pathway; Transcription co-factors SKI and SKIL protein partners; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-YAP signaling; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; Leukocyte-intrinsic Hippo pathway functions; Pleural mesothelioma"	"9"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UHB7"	"AF4/FMR2 family member 4 OS=Homo sapiens OX=9606 GN=AFF4 PE=1 SV=1"	""	""	"1"	"1"	"1"	"1"	"1163"	"127.4"	"9.31"	""	"2.11"	""	"1"	"stress response;other biological processes"	"nucleus;other cell component"	""	"Pf05110, Pf18875, Pf18876"	"27125"	"ENSG00000072364"	"AFF4"	"B2RP19; B7WPD2; hsa:27125; Q498B2; Q59FB3; Q6P592; Q8TDR1; Q9P0E4; Q9UHB7"	"Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events"	""	"3"	"0"	"15.8"	"11.5"	"16.1"	"13.6"	"17.6"	"20.4"	"14.0"	"23.1"	"20.4"	"60.6"	"138.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q02388"	"Collagen alpha-1(VII) chain OS=Homo sapiens OX=9606 GN=COL7A1 PE=1 SV=2"	""	""	"0"	"1"	"1"	"1"	"2944"	"295.0"	"6.27"	""	"2.11"	""	"1"	"cell adhesion;cell organization and biogenesis;developmental processes;other biological processes"	"non-structural extracellular;extracellular matrix;other membranes;ER/Golgi;other cell component"	"enzyme regulator activity;extracellular structural activity"	"Pf00014, Pf00041, Pf00092, Pf01391"	"1294"	"ENSG00000114270"	"COL7A1"	"hsa:1294; Q02388; Q14054; Q16507"	"Collagen degradation; Integrin cell surface interactions; Collagen chain trimerization; COPII-mediated vesicle transport; Cargo concentration in the ER; Laminin interactions; Anchoring fibril formation"	""	"10"	"0"	"67.5"	"27.8"	"58.3"	"51.2"	"60.6"	"71.0"	"42.1"	"74.4"	"64.5"	"382.7"	"893.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H977"	"WD repeat-containing protein 54 OS=Homo sapiens OX=9606 GN=WDR54 PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"334"	"35.9"	"6.20"	""	"2.10"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"other molecular function"	""	"84058"	"ENSG00000005448"	"WDR54"	"B9A049; D6W5I3; hsa:84058; Q53H85; Q86V45; Q9H977"	""	""	"0"	"0"	"48.8"	"10.4"	"38.1"	"35.1"	"56.3"	"64.7"	"30.1"	"45.1"	"13.7"	"60.0"	"177.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9BQ24"	"Zinc finger FYVE domain-containing protein 21 OS=Homo sapiens OX=9606 GN=ZFYVE21 PE=1 SV=1"	""	""	"7"	"1"	"1"	"1"	"234"	"26.5"	"8.41"	""	"2.10"	""	"1"	""	"other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01363, Pf16696"	"79038"	"ENSG00000100711"	"ZFYVE21"	"A8K3A4; hsa:79038; Q86T05; Q96LT1; Q9BQ24"	""	""	"0"	"0"	"9.9"	"3.3"	"5.8"	"7.0"	"3.7"	"7.6"	"4.3"	"10.5"	"6.3"	"21.8"	"37.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9HCM4"	"Band 4.1-like protein 5 OS=Homo sapiens OX=9606 GN=EPB41L5 PE=1 SV=3"	""	""	"2"	"1"	"1"	"1"	"733"	"81.8"	"6.58"	""	"2.08"	""	"1"	"cell adhesion;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf08736, Pf09379, Pf09380"	"57669"	"ENSG00000115109"	"EPB41L5"	"hsa:57669; Q7Z5S1; Q8IZ12; Q9H975; Q9HCM4"	"Neurexins and neuroligins"	"Endoderm differentiation; Mesodermal commitment pathway; Mesodermal commitment pathway"	"4"	"0"	"94.5"	"42.2"	"74.1"	"63.7"	"70.0"	"80.1"	"59.3"	"78.2"	"90.0"	"195.9"	"268.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q15349"	"Ribosomal protein S6 kinase alpha-2 OS=Homo sapiens OX=9606 GN=RPS6KA2 PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"733"	"83.2"	"8.68"	""	"2.08"	""	"1"	"cell-cell signaling;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00433"	"6196"	"ENSG00000071242"	"RPS6KA2"	"B3KTK9; hsa:6196; Q15349; Q15419; Q59GJ3; Q5TI68; Q96J38; Q9UJN5"	"Senescence-Associated Secretory Phenotype (SASP); Recycling pathway of L1; RSK activation; ERK/MAPK targets; CREB phosphorylation; Gastrin-CREB signalling pathway via PKC and MAPK"	"Prolactin signaling pathway; Angiopoietin-like protein 8 regulatory pathway; Thermogenesis; EGF/EGFR signaling pathway; Translation inhibitors in chronically activated PDGFRA cells; Cytoplasmic ribosomal proteins; Insulin signaling; Host-pathogen interaction of human coronaviruses - MAPK signaling"	"15"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q6NSJ5"	"Volume-regulated anion channel subunit LRRC8E OS=Homo sapiens OX=9606 GN=LRRC8E PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"796"	"90.2"	"6.96"	""	"2.08"	""	"1"	"cell organization and biogenesis;stress response;transport"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"transporter activity"	"Pf12534, Pf13855"	"80131"	"ENSG00000171017"	"LRRC8E"	"B3KR78; hsa:80131; Q2YDY3; Q6NSJ5; Q7L236; Q8N3B0; Q9H5H8"	"Miscellaneous transport and binding events"	"Neuroinflammation and glutamatergic signaling"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q3V6T2"	"Girdin OS=Homo sapiens OX=9606 GN=CCDC88A PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1871"	"215.9"	"6.21"	""	"2.08"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf19047"	"55704"	"ENSG00000115355"	"CCDC88A"	"A1IGE7; B7ZM78; C9JG83; hsa:55704; Q3V6T2; Q53SF1; Q581G3; Q5HYD0; Q7Z339; Q7Z3C5"	"RND3 GTPase cycle; RND1 GTPase cycle"	"Mesodermal commitment pathway"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8WXK1"	"Ankyrin repeat and SOCS box protein 15 OS=Homo sapiens OX=9606 GN=ASB15 PE=1 SV=3"	""	""	"3"	"1"	"1"	"1"	"588"	"65.8"	"5.83"	""	"2.08"	""	"1"	"protein metabolism;other metabolic processes;transport;signal transduction"	"other membranes;cytosol;other cytoplasmic organelle"	"other molecular function"	"Pf07525, Pf12796"	"142685"	"ENSG00000146809"	"ASB15"	"hsa:142685; Q3ZCP3; Q3ZCP5; Q68D37; Q8WXK1"	"Antigen processing: Ubiquitination & Proteasome degradation; Neddylation"	""	"2"	"0"	"138.9"	"52.9"	"91.9"	"62.4"	"89.3"	"78.1"	"78.1"	"92.4"	"95.1"	"190.9"	"342.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z460"	"CLIP-associating protein 1 OS=Homo sapiens OX=9606 GN=CLASP1 PE=1 SV=1"	"0.001"	""	"1"	"1"	"2"	"1"	"1538"	"169.3"	"9.03"	"243.58"	"2.08"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02985, Pf12348"	"23332"	"ENSG00000074054"	"CLASP1"	"A2RU21; B7ZLX3; F5GWS0; hsa:23332; O75118; Q2KHQ9; Q5H9P0; Q7Z460; Q8N5B8; Q9BQT5"	"Anchoring of the basal body to the plasma membrane; Separation of Sister Chromatids; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; AURKA Activation by TPX2; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Role of ABL in ROBO-SLIT signaling"	"Microtubule cytoskeleton regulation; Splicing factor NOVA regulated synaptic proteins; 7q11.23 copy number variation syndrome"	"17"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95429"	"BAG family molecular chaperone regulator 4 OS=Homo sapiens OX=9606 GN=BAG4 PE=1 SV=1"	"0.001"	""	"2"	"1"	"2"	"1"	"457"	"49.6"	"5.12"	"236.61"	"2.07"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	"other molecular function"	"Pf02179"	"9530"	"ENSG00000156735"	"BAG4"	"B4E217; hsa:9530; O95429; O95818"	"Signaling by FGFR1 in disease; Regulation of HSF1-mediated heat shock response; Signaling by plasma membrane FGFR1 fusions; TNF signaling"	"Oxidative damage response"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8WXW3"	"Progesterone-induced-blocking factor 1 OS=Homo sapiens OX=9606 GN=PIBF1 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"757"	"89.8"	"6.02"	""	"2.07"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding"	""	"10464"	"ENSG00000083535"	"PIBF1"	"hsa:10464; O95664; Q6U9V2; Q6UG50; Q86V07; Q8WXW3; Q96SF4"	""	"Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q86X95"	"Corepressor interacting with RBPJ 1 OS=Homo sapiens OX=9606 GN=CIR1 PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"450"	"52.3"	"9.86"	""	"2.06"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf10197"	"9541"	"ENSG00000138433"	"CIR1"	"A6NFI6; A8K8M4; hsa:9541; O95367; Q12804; Q4G1B9; Q6PJI4; Q86X95; Q8IWI2"	""	"Notch signaling pathway"	"1"	"0"	"21.9"	"9.4"	"18.8"	"9.7"	"16.0"	"16.0"	"14.8"	"18.4"	"25.9"	"54.7"	"108.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8N1H7"	"Protein SIX6OS1 OS=Homo sapiens OX=9606 GN=SIX6OS1 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"587"	"68.1"	"5.54"	""	"2.06"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;stress response;other biological processes"	"nucleus;other cell component"	""	"Pf15676"	"317761"	"ENSG00000179008"	"SIX6OS1"	"hsa:317761; Q08AQ4; Q8N1H7"	""	"Primary ovarian insufficiency"	"1"	"0"	"19.4"	"4.2"	"19.5"	"18.8"	"29.3"	"61.5"	"98.6"	"273.3"	"178.0"	"445.7"	"353.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y2R9"	"28S ribosomal protein S7, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS7 PE=1 SV=2"	""	""	"5"	"1"	"1"	"1"	"242"	"28.1"	"9.99"	""	"2.06"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00177"	"51081"	"ENSG00000125445"	"MRPS7"	"B2R9N5; hsa:51081; Q53GD6; Q9Y2R9"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q6P1M0"	"Long-chain fatty acid transport protein 4 OS=Homo sapiens OX=9606 GN=SLC27A4 PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"643"	"72.0"	"8.47"	""	"2.06"	""	"1"	"other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"transporter activity;other molecular function"	"Pf00501, Pf13193"	"10999"	"ENSG00000167114"	"SLC27A4"	"A8K2F7; hsa:10999; O95186; Q6P1M0; Q96G53"	"Transport of fatty acids; Defective SLC27A4 causes ichthyosis prematurity syndrome (IPS)"	"PPAR signaling pathway; Fatty acid transporters; Cholesterol metabolism; Fatty Acids and Lipoproteins Transport in Hepatocytes; Enterocyte cholesterol metabolism"	"7"	"0"	"300.7"	"81.8"	"181.6"	"145.3"	"193.4"	"217.2"	"174.6"	"232.4"	"183.1"	"311.4"	"462.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q5VWI1"	"Transcription elongation regulator 1-like protein OS=Homo sapiens OX=9606 GN=TCERG1L PE=2 SV=2"	""	""	"1"	"1"	"1"	"1"	"586"	"65.6"	"9.83"	""	"2.05"	""	"1"	"other biological processes"	"nucleus"	"other molecular function"	"Pf01846"	"256536"	"ENSG00000176769"	"TCERG1L"	"hsa:256536; Q5VWI1; Q5VWI2; Q86XM8"	""	""	"0"	"0"	"365.9"	"110.7"	"283.1"	"235.2"	"309.7"	"402.8"	"228.4"	"339.3"	"219.0"	"481.0"	"882.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P45974"	"Ubiquitin carboxyl-terminal hydrolase 5 OS=Homo sapiens OX=9606 GN=USP5 PE=1 SV=2"	"0.000"	""	"3"	"2"	"2"	"2"	"858"	"95.7"	"5.03"	"1014.06"	""	"2"	""	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf00443, Pf00627, Pf02148, Pf17807"	"8078"	"ENSG00000111667"	"USP5"	"D3DUS7; D3DUS8; hsa:8078; P45974; Q96J22"	"Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Ub-specific processing proteases"	"IL-18 signaling pathway"	"3"	"0"	"89.7"	"44.3"	"84.5"	"67.4"	"81.4"	"79.7"	"64.1"	"71.3"	"60.6"	"94.0"	"147.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P06746"	"DNA polymerase beta OS=Homo sapiens OX=9606 GN=POLB PE=1 SV=3"	"0.000"	""	"4"	"1"	"2"	"1"	"335"	"38.2"	"8.95"	"948.34"	""	"1"	""	"DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf10391, Pf14716, Pf14791, Pf14792"	"5423"	"ENSG00000070501"	"POLB"	"B2RC78; hsa:5423; P06746; Q3KP48; Q6FI34"	"Ub-specific processing proteases; APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway; POLB-Dependent Long Patch Base Excision Repair; PCNA-Dependent Long Patch Base Excision Repair; Abasic sugar-phosphate removal via the single-nucleotide replacement pathway"	"Male infertility; Base excision repair; DNA repair pathways, full network"	"10"	"0"	"25.7"	"6.3"	"29.8"	"14.5"	"22.6"	"17.3"	"19.2"	"34.0"	"49.7"	"165.1"	"229.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62072"	"Mitochondrial import inner membrane translocase subunit Tim10 OS=Homo sapiens OX=9606 GN=TIMM10 PE=1 SV=1"	"0.000"	""	"22"	"2"	"2"	"2"	"90"	"10.3"	"6.29"	"840.03"	""	"2"	""	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf02953"	"26519"	"ENSG00000134809"	"TIMM10"	"A8K136; hsa:26519; P62072; Q9WV99; Q9WVA0; Q9Y5J8"	"Mitochondrial protein import"	""	"1"	"0"	"224.3"	"110.2"	"209.4"	"211.8"	"231.0"	"271.5"	"193.5"	"248.2"	"176.5"	"333.9"	"486.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63000"	"Ras-related C3 botulinum toxin substrate 1 OS=Homo sapiens OX=9606 GN=RAC1 PE=1 SV=1"	"0.000"	""	"8"	"1"	"2"	"1"	"192"	"21.4"	"8.50"	"803.73"	""	"1"	""	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00071"	"5879"	"ENSG00000136238"	"RAC1"	"hsa:5879; O95501; P15154; P63000; Q3Y4D3; Q5JAA8; Q9BTB4"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; EPHB-mediated forward signaling; RAC1 GTPase cycle; NRAGE signals death through JNK; DCC mediated attractive signaling; Neutrophil degranulation; PIP3 activates AKT signaling; Constitutive Signaling by Aberrant PI3K in Cancer; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; FCERI mediated MAPK activation; MAPK6/MAPK4 signaling; Translocation of SLC2A4 (GLUT4) to the plasma membrane; RHO GTPases activate IQGAPs; RHO GTPases Activate Formins; GPVI-mediated activation cascade; Signaling by SCF-KIT; DAP12 signaling; Ephrin signaling; Factors involved in megakaryocyte development and platelet production; RHO GTPases activate CIT; PCP/CE pathway; WNT5:FZD7-mediated leishmania damping; EPH-ephrin mediated repulsion of cells; Sema3A PAK dependent Axon repulsion; SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion; Signal transduction by L1; RHO GTPases activate PKNs; RHO GTPases activate PAKs; DSCAM interactions; Azathioprine ADME; VEGFR2 mediated vascular permeability; Sema4D mediated inhibition of cell attachment and migration; Inactivation of CDC42 and RAC1; Activation of RAC1; CD28 dependent Vav1 pathway; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases; Nef and signal transduction; RHO GTPases Activate NADPH Oxidases; NTRK2 activates RAC1; MET activates RAP1 and RAC1; Activation of RAC1 downstream of NMDARs; Activated NTRK2 signals through CDK5; RHO GTPases activate KTN1"	"Androgen receptor signaling pathway; Nucleotide-binding oligomerization domain (NOD) pathway; Target of rapamycin signaling; Physiological and pathological hypertrophy of the heart; MicroRNAs in cardiomyocyte hypertrophy; Integrin-mediated cell adhesion; RANKL/RANK signaling pathway; Leptin signaling pathway; TNF-related weak inducer of apoptosis (TWEAK) signaling pathway; Prolactin signaling pathway; Microtubule cytoskeleton regulation; RalA downstream regulated genes; B cell receptor signaling pathway; TNF-alpha signaling pathway; AGE/RAGE pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Spinal cord injury; Alpha 6 beta 4 signaling pathway; Amyotrophic lateral sclerosis (ALS); Cardiac hypertrophic response; Focal adhesion; RAC1/PAK1/p38/MMP2 pathway; Wnt signaling pathway; IL6 signaling pathway; Hepatitis C and hepatocellular carcinoma; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Microglia pathogen phagocytosis pathway; Robo4 and VEGF signaling pathways crosstalk; p38 MAPK signaling pathway; PI3K-Akt signaling pathway; Chromosomal and microsatellite instability in colorectal cancer ; Ebola virus infection in host; Ras signaling; Pancreatic adenocarcinoma pathway; Wnt signaling; Ciliary landscape; EGF/EGFR signaling pathway; Nonalcoholic fatty liver disease; Hippo signaling regulation pathways; Leukocyte-intrinsic Hippo pathway functions; Neural crest cell migration during development; Neural crest cell migration in cancer; Gastrin signaling pathway; Melanoma; Netrin-UNC5B signaling pathway; Insulin signaling; CAMKK2 pathway; Opioid receptor pathways; Regulation of actin cytoskeleton; GDNF signaling; 2q13 copy number variation syndrome; 2q21.1 copy number variation syndrome; 2q37 copy number variation syndrome; G13 signaling pathway; Genetic causes of porto-sinusoidal vascular disease; TROP2 regulatory signaling; 13q12.12 copy number variation; Interferon type I signaling pathways; DNA damage response (only ATM dependent); Toll-like receptor signaling pathway"	"108"	"0"	"50.0"	"18.0"	"44.2"	"29.4"	"46.2"	"44.7"	"33.0"	"40.1"	"34.6"	"79.9"	"124.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z406"	"Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2"	"0.000"	""	"1"	"2"	"2"	"1"	"1995"	"227.7"	"5.60"	"780.42"	""	"2"	""	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00063, Pf01576, Pf02736"	"79784"	"ENSG00000105357"	"MYH14"	"B0I1S2; C3TTN4; hsa:79784; Q5CZ75; Q6XYE4; Q76B62; Q7Z406; Q8WV23; Q96I22; Q9BT27; Q9BW35; Q9H882"	"RHO GTPases activate CIT; RHO GTPases activate PKNs; RHO GTPases activate PAKs; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; RHO GTPases Activate ROCKs"	""	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WWK9"	"Cytoskeleton-associated protein 2 OS=Homo sapiens OX=9606 GN=CKAP2 PE=1 SV=1"	"0.000"	""	"3"	"2"	"2"	"2"	"683"	"76.9"	"9.41"	"759.78"	""	"2"	""	"cell cycle OR cell proliferation;other biological processes"	"cytoskeleton;other cell component"	""	"Pf15297"	"26586"	"ENSG00000136108"	"CKAP2"	"A2BDE0; A5YM58; B4DR35; E9PD90; hsa:26586; Q3KRA5; Q5VXB4; Q8IWV5; Q8IWV6; Q8WWK9; Q96FH9; Q9H012; Q9H0D0; Q9H988; Q9HC49; Q9NVG4"	""	""	"0"	"0"	"125.9"	"63.3"	"125.9"	"119.5"	"127.2"	"150.7"	"105.8"	"202.1"	"108.5"	"260.4"	"340.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75334"	"Liprin-alpha-2 OS=Homo sapiens OX=9606 GN=PPFIA2 PE=1 SV=2"	"0.000"	""	"2"	"2"	"2"	"2"	"1257"	"143.2"	"6.11"	"697.09"	""	"2"	""	"cell adhesion;cell organization and biogenesis;transport;other biological processes"	"cytosol;other cell component"	""	"Pf00536, Pf07647"	"8499"	"ENSG00000139220"	"PPFIA2"	"B3KVT5; B3KXA0; B7Z2A6; B7Z3U9; B7Z663; B7ZKZ5; E7ERB8; E7ETG6; F8VP68; hsa:8499; O75334; Q2M3G8"	"Glutamate Neurotransmitter Release Cycle; Serotonin Neurotransmitter Release Cycle; Norepinephrine Neurotransmitter Release Cycle; Dopamine Neurotransmitter Release Cycle; Acetylcholine Neurotransmitter Release Cycle; Receptor-type tyrosine-protein phosphatases"	""	"6"	"0"	"78.3"	"26.1"	"59.7"	"44.3"	"57.0"	"65.6"	"42.2"	"76.3"	"50.9"	"117.8"	"169.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q71RC2"	"La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3"	"0.000"	""	"2"	"1"	"1"	"1"	"724"	"80.5"	"6.61"	"695.93"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity"	"Pf05383"	"113251"	"ENSG00000161813"	"LARP4"	"A8K6T1; E9PDG5; G3XAA8; G5E976; hsa:113251; Q5CZ97; Q6ZV14; Q71RC2; Q96NF9"	""	""	"0"	"0"	"61.3"	"26.0"	"64.8"	"49.6"	"56.6"	"83.9"	"42.2"	"66.8"	"37.9"	"72.8"	"92.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60524"	"Nuclear export mediator factor NEMF OS=Homo sapiens OX=9606 GN=NEMF PE=1 SV=4"	"0.000"	""	"1"	"1"	"1"	"1"	"1076"	"122.9"	"6.35"	"662.34"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf05670, Pf05833, Pf11923"	"9147"	"ENSG00000165525"	"NEMF"	"A0JLQ3; B3KSK1; B4DDL3; B4DHA9; B4E3F3; hsa:9147; O60524; Q32Q66; Q8WW70; Q9NWG1"	""	""	"0"	"0"	"43.3"	"17.7"	"41.7"	"32.7"	"42.4"	"43.9"	"32.1"	"42.5"	"44.4"	"108.9"	"219.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"B7ZAP0"	"Rab GTPase-activating protein 1-like, isoform 10 OS=Homo sapiens OX=9606 GN=RABGAP1L PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"253"	"29.0"	"5.33"	"649.03"	""	"1"	""	""	""	""	""	"9910"	"ENSG00000152061"	"RABGAP1L"	"B7ZAA4; B7ZAP0; hsa:9910"	""	""	"0"	"0"	"451.3"	"156.3"	"494.2"	"401.7"	"455.4"	"537.7"	"310.6"	"400.0"	"256.7"	"560.5"	"751.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92552"	"28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3"	"0.000"	""	"5"	"2"	"2"	"2"	"414"	"47.6"	"6.18"	"635.84"	""	"2"	""	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf10037"	"23107"	"ENSG00000113048"	"MRPS27"	"B4DRT2; hsa:23107; Q6P1S1; Q92552"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"99.9"	"32.9"	"74.6"	"62.4"	"82.3"	"85.4"	"70.3"	"89.4"	"72.7"	"148.8"	"379.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P02768"	"Serum albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2"	"0.000"	""	"2"	"1"	"1"	"1"	"609"	"69.3"	"6.28"	"632.96"	""	"1"	""	"stress response;other biological processes"	"non-structural extracellular;ER/Golgi;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00273"	"213"	"ENSG00000163631"	"ALB"	"E7ESS9; hsa:213; O95574; P02768; P04277; Q13140; Q645G4; Q68DN5; Q6UXK4; Q86YG0; Q8IUK7; Q9P157; Q9P1I7; Q9UHS3; Q9UJZ0"	"Scavenging of heme from plasma; Platelet degranulation ; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Cytoprotection by HMOX1; Aspirin ADME; Ciprofloxacin ADME; Recycling of bile acids and salts; Prednisone ADME; Heme degradation; HDL remodeling; Heme biosynthesis"	"Selenium micronutrient network; Vitamin B12 metabolism; Folate metabolism; Complement system; VEGFA-VEGFR2 signaling"	"17"	"0"	"14.8"	"484.5"	"18.3"	"0.0"	"10.9"	"8.1"	"10.2"	"10.0"	"14.5"	"24.3"	"35.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULX3"	"RNA-binding protein NOB1 OS=Homo sapiens OX=9606 GN=NOB1 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"412"	"46.6"	"7.18"	"616.03"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf08772, Pf15017, Pf17146"	"28987"	"ENSG00000141101"	"NOB1"	"hsa:28987; Q7L6B7; Q7M4M4; Q7Z4B5; Q9NWB0; Q9ULX3"	"Major pathway of rRNA processing in the nucleolus and cytosol"	""	"1"	"0"	"30.1"	"7.1"	"28.5"	"19.9"	"26.3"	"27.8"	"16.9"	"27.5"	"21.4"	"54.4"	"150.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NXX6"	"Non-structural maintenance of chromosomes element 4 homolog A OS=Homo sapiens OX=9606 GN=NSMCE4A PE=1 SV=2"	"0.000"	""	"6"	"2"	"2"	"2"	"385"	"44.3"	"5.38"	"615.36"	""	"2"	""	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	""	"Pf08743, Pf15412"	"54780"	"ENSG00000107672"	"NSMCE4A"	"hsa:54780; Q5SQQ5; Q6P673; Q8WY66; Q9BS90; Q9NXX6"	"SUMOylation of DNA damage response and repair proteins"	""	"1"	"0"	"59.0"	"22.9"	"53.9"	"40.4"	"57.0"	"49.7"	"49.9"	"65.5"	"53.3"	"126.5"	"425.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27824"	"Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2"	"0.000"	""	"3"	"1"	"1"	"1"	"592"	"67.5"	"4.60"	"563.89"	""	"1"	""	"protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;translational apparatus;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00262"	"821"	"ENSG00000127022; ENSG00000283777"	"CANX"	"B2R5V8; B4DGP8; B4E2T8; D3DWQ3; D6R9K3; hsa:821; P27824"	"Maturation of spike protein; MHC class II antigen presentation; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Interleukin-35 Signalling; Interleukin-27 signaling; Assembly of Viral Components at the Budding Site; Calnexin/calreticulin cycle; Maturation of spike protein"	"15q11q13 copy number variation"	"9"	"0"	"87.5"	"15.3"	"27.9"	"15.0"	"34.9"	"33.5"	"32.8"	"55.9"	"60.9"	"64.1"	"130.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H6R0"	"ATP-dependent RNA helicase DHX33 OS=Homo sapiens OX=9606 GN=DHX33 PE=1 SV=2"	"0.000"	""	"2"	"1"	"1"	"1"	"707"	"78.8"	"8.91"	"549.45"	""	"1"	""	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"56919"	"ENSG00000005100"	"DHX33"	"B4DHF9; hsa:56919; Q4G149; Q5CZ73; Q9H5M9; Q9H6R0"	""	""	"0"	"0"	"8.1"	"4.2"	"9.7"	"12.1"	"9.4"	"10.6"	"6.5"	"15.7"	"8.4"	"17.7"	"26.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q06323"	"Proteasome activator complex subunit 1 OS=Homo sapiens OX=9606 GN=PSME1 PE=1 SV=1"	"0.000"	""	"4"	"1"	"1"	"1"	"249"	"28.7"	"6.02"	"529.63"	""	"1"	""	"other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf02251, Pf02252"	"5720"	"ENSG00000092010; ENSG00000284916"	"PSME1"	"A6NJG9; H0YNE3; hsa:5720; Q06323; Q6IBM2; Q9UEF4"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation"	"60"	"0"	"103.2"	"42.4"	"80.3"	"74.9"	"89.1"	"90.6"	"73.9"	"83.0"	"55.0"	"107.9"	"196.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82912"	"28S ribosomal protein S11, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS11 PE=1 SV=2"	"0.000"	""	"9"	"1"	"1"	"1"	"194"	"20.6"	"10.81"	"524.67"	""	"1"	""	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00411"	"64963"	"ENSG00000181991"	"MRPS11"	"B2RD52; hsa:64963; P82912; Q969D7; Q96GI3; Q9BYC3"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BRR8"	"G patch domain-containing protein 1 OS=Homo sapiens OX=9606 GN=GPATCH1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"1"	"1"	"931"	"103.3"	"7.05"	"515.70"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf01585, Pf07713"	"55094"	"ENSG00000076650"	"GPATCH1"	"hsa:55094; Q8IZV6; Q8N3B7; Q9BRR8; Q9NW94"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"43.2"	"10.7"	"27.0"	"26.3"	"26.2"	"26.5"	"23.2"	"32.9"	"22.5"	"78.6"	"90.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IUD2"	"ELKS/Rab6-interacting/CAST family member 1 OS=Homo sapiens OX=9606 GN=ERC1 PE=1 SV=1"	"0.000"	""	"2"	"2"	"2"	"2"	"1116"	"128.0"	"5.97"	"503.09"	""	"2"	""	"cell-cell signaling;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf09457, Pf10174"	"23085"	"ENSG00000082805"	"ERC1"	"A2RU77; A7E295; D3DUP7; D3DUP8; hsa:23085; Q6NVK2; Q8IUD2; Q8IUD3; Q8IUD4; Q8IUD5; Q8NAS1; Q9NXN5; Q9UIK7; Q9UPS1"	""	""	"0"	"0"	"358.2"	"115.1"	"295.7"	"244.8"	"291.2"	"312.7"	"215.8"	"299.0"	"218.8"	"443.4"	"659.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P021"	"Cysteine-rich PDZ-binding protein OS=Homo sapiens OX=9606 GN=CRIPT PE=1 SV=1"	"0.000"	""	"12"	"1"	"1"	"1"	"101"	"11.2"	"9.47"	"500.10"	""	"1"	""	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf10235"	"9419"	"ENSG00000119878"	"CRIPT"	"hsa:9419; Q9P021"	""	""	"0"	"0"	"17.6"	"7.3"	"22.5"	"17.7"	"20.7"	"24.4"	"24.2"	"24.3"	"16.6"	"76.0"	"103.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H0H5"	"Rac GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RACGAP1 PE=1 SV=1"	"0.000"	""	"4"	"2"	"2"	"2"	"632"	"71.0"	"8.88"	"489.38"	""	"2"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00130, Pf00620"	"29127"	"ENSG00000161800"	"RACGAP1"	"hsa:29127; Q6PJ26; Q9H0H5; Q9NWN2; Q9P250; Q9P2W2"	"COPI-dependent Golgi-to-ER retrograde traffic; MHC class II antigen presentation; Kinesins; RHOC GTPase cycle; RHOA GTPase cycle; RAC2 GTPase cycle; RHOD GTPase cycle; RAC1 GTPase cycle; RAC3 GTPase cycle; CDC42 GTPase cycle; RHOB GTPase cycle"	"S1P receptor signal transduction; Wnt signaling pathway and pluripotency"	"13"	"0"	"133.9"	"47.7"	"88.1"	"70.8"	"89.3"	"85.3"	"74.9"	"79.9"	"87.7"	"172.9"	"295.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60551"	"Glycylpeptide N-tetradecanoyltransferase 2 OS=Homo sapiens OX=9606 GN=NMT2 PE=1 SV=1"	"0.000"	""	"3"	"1"	"1"	"1"	"498"	"56.9"	"7.58"	"479.40"	""	"1"	""	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf01233, Pf02799"	"9397"	"ENSG00000152465"	"NMT2"	"B0YJ49; hsa:9397; O60551; Q53Y38; Q5VUC8; Q9BRB4"	"Membrane binding and targetting of GAG proteins; Inactivation, recovery and regulation of the phototransduction cascade"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6I4"	"Ubiquitin carboxyl-terminal hydrolase 3 OS=Homo sapiens OX=9606 GN=USP3 PE=1 SV=2"	"0.000"	""	"3"	"1"	"1"	"1"	"520"	"58.9"	"8.18"	"470.00"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf00443, Pf02148"	"9960"	"ENSG00000140455"	"USP3"	"B4DVU5; F5H1A6; hsa:9960; Q8WVD0; Q9Y6I4"	"Ub-specific processing proteases"	""	"1"	"0"	"7.7"	"2.2"	"7.8"	"7.8"	"4.3"	"9.9"	"7.3"	"11.3"	"9.3"	"19.0"	"43.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15631"	"Translin OS=Homo sapiens OX=9606 GN=TSN PE=1 SV=1"	"0.000"	""	"5"	"1"	"1"	"1"	"228"	"26.2"	"6.44"	"469.14"	""	"1"	""	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01997"	"7247"	"ENSG00000211460"	"TSN"	"B7Z3X8; hsa:7247; Q15631; Q5U0K7"	"Small interfering RNA (siRNA) biogenesis"	""	"1"	"0"	"21.2"	"4.7"	"16.0"	"11.2"	"18.9"	"17.3"	"13.0"	"19.8"	"17.5"	"17.9"	"30.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95619"	"YEATS domain-containing protein 4 OS=Homo sapiens OX=9606 GN=YEATS4 PE=1 SV=1"	"0.000"	""	"4"	"1"	"1"	"1"	"227"	"26.5"	"8.41"	"415.18"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03366"	"8089"	"ENSG00000127337"	"YEATS4"	"hsa:8089; O95619; Q9NQD0"	"HATs acetylate histones; Activation of the TFAP2 (AP-2) family of transcription factors"	""	"2"	"0"	"211.5"	"65.5"	"195.6"	"178.9"	"208.1"	"244.0"	"146.9"	"226.3"	"130.2"	"365.9"	"565.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NX55"	"Huntingtin-interacting protein K OS=Homo sapiens OX=9606 GN=HYPK PE=1 SV=2"	"0.000"	""	"12"	"1"	"1"	"1"	"129"	"14.7"	"4.93"	"408.48"	""	"1"	""	"protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf04419, Pf19026"	"100137436; 101127706; 104002286; 104679625; 105491324; 105549422; 105588143; 108521295; 25764; 713266"	"ENSCATG00000038565; ENSGGOG00000014809; ENSMFAG00000057677; ENSMLEG00000000898; ENSMMUG00000022768; ENSMNEG00000018318; ENSPANG00000018102; ENSPPAG00000034659; ENSPTEG00000009792; ENSPTEG00000019135; ENSPTRG00000038721; ENSRBIG00000028237; ENSRROG00000039445; ENSTGEG00000007663"	"HYPK; LOC113219833"	"A0A024R5Q1; A0A1D5R5K3; A0A2I2YQJ1; A0A2J8NTT0; A0A2K5N035; A0A2K5TR12; A0A2K5XAQ0; A0A2K6AXP0; A0A2K6KBN5; A0A2K6QRU2; A0A2R9B6N1; A0A663DGD1; A0A6D2Y1W8; A0A8C9GZF6; A0A8D2ERJ4; A0A8J8XMG0; A9X1C4; F7GC11; G7MX15; G7PB77; H2Q9B3; hsa:25764; mcc:713266; mleu:105549422; mni:105491324; panu:100137436; ptr:104002286; rbb:108521295; rro:104679625"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50454"	"Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2"	"0.000"	""	"3"	"1"	"1"	"1"	"418"	"46.4"	"8.69"	"398.03"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;other membranes;ER/Golgi"	"enzyme regulator activity;other molecular function"	"Pf00079"	"871"	"ENSG00000149257"	"SERPINH1"	"B3KVJ3; hsa:871; P29043; P50454; Q5XPB4; Q6NSJ6; Q8IY96; Q9NP88"	"Collagen biosynthesis and modifying enzymes"	"Endochondral ossification; Type I collagen synthesis in the context of osteogenesis imperfecta; Endochondral ossification with skeletal dysplasias; 15q13.3 copy number variation syndrome; 15q11q13 copy number variation"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P34741"	"Syndecan-2 OS=Homo sapiens OX=9606 GN=SDC2 PE=1 SV=2"	"0.000"	""	"4"	"1"	"1"	"1"	"201"	"22.1"	"4.86"	"395.27"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01034"	"6383"	"ENSG00000169439"	"SDC2"	"B3KQA3; hsa:6383; P34741; Q6PIS6; Q9H6V1"	"Cell surface interactions at the vascular wall; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; EPHB-mediated forward signaling; A tetrasaccharide linker sequence is required for GAG synthesis; HS-GAG biosynthesis; HS-GAG degradation; Defective B4GALT7 causes EDS, progeroid type; Defective B3GAT3 causes JDSSDHD; Defective EXT2 causes exostoses 2; Defective EXT1 causes exostoses 1, TRPS2 and CHDS; Defective B3GALT6 causes EDSP2 and SEMDJL1; Attachment and Entry; Retinoid metabolism and transport; Syndecan interactions"	"miRNA targets in ECM and membrane receptors"	"16"	"0"	"37.8"	"11.1"	"32.1"	"24.2"	"27.1"	"33.8"	"23.6"	"28.4"	"24.9"	"35.8"	"61.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49137"	"MAP kinase-activated protein kinase 2 OS=Homo sapiens OX=9606 GN=MAPKAPK2 PE=1 SV=1"	"0.000"	""	"3"	"1"	"1"	"1"	"400"	"45.5"	"8.68"	"391.38"	""	"1"	""	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"9261"	"ENSG00000162889"	"MAPKAPK2"	"hsa:9261; P49137; Q5SY30; Q5SY41; Q8IYD6"	"Oxidative Stress Induced Senescence; Regulation of HSF1-mediated heat shock response; VEGFA-VEGFR2 Pathway; Regulation of TNFR1 signaling; p38MAPK events; activated TAK1 mediates p38 MAPK activation; CREB phosphorylation; Synthesis of Leukotrienes (LT) and Eoxins (EX); Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"	"IL-1 signaling pathway; Microtubule cytoskeleton regulation; Interleukin-1 (IL-1) structural pathway; Fas ligand pathway and stress induction of heat shock proteins; MAPK signaling pathway; VEGFA-VEGFR2 signaling; p38 MAPK signaling pathway; Pleural mesothelioma; Serotonin HTR1 group and FOS pathway; Serotonin receptor 2 and ELK-SRF/GATA4 signaling; Serotonin receptor 4/6/7 and NR3C signaling"	"21"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3A3"	"MOB-like protein phocein OS=Homo sapiens OX=9606 GN=MOB4 PE=1 SV=1"	"0.000"	""	"4"	"1"	"1"	"1"	"225"	"26.0"	"5.78"	"389.09"	""	"1"	""	""	"other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf03637"	"25843"	"ENSG00000115540"	"MOB4"	"B4DML0; hsa:25843; Q53SE0; Q7Z4Y6; Q9H2P3; Q9H5J1; Q9Y3A3; Q9Y4T8"	""	""	"0"	"0"	"22.8"	"14.0"	"26.0"	"20.8"	"21.0"	"26.3"	"17.4"	"18.9"	"21.1"	"39.6"	"62.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14192"	"Four and a half LIM domains protein 2 OS=Homo sapiens OX=9606 GN=FHL2 PE=1 SV=3"	"0.000"	""	"4"	"1"	"1"	"1"	"279"	"32.2"	"7.55"	"378.77"	""	"1"	""	"developmental processes;other biological processes"	"cytoskeleton;nucleus"	"other molecular function"	"Pf00412"	"2274"	"ENSG00000115641"	"FHL2"	"hsa:2274; Q13229; Q13644; Q14192; Q2I5I4; Q5TM15; Q9P294"	"PPARA activates gene expression"	"Androgen receptor signaling pathway; RANKL/RANK signaling pathway; Ectoderm differentiation; VEGFA-VEGFR2 signaling"	"5"	"0"	"136.5"	"77.8"	"149.8"	"115.9"	"140.8"	"172.4"	"125.4"	"154.4"	"132.3"	"163.8"	"182.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NB46"	"Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C OS=Homo sapiens OX=9606 GN=ANKRD52 PE=1 SV=3"	"0.000"	""	"2"	"1"	"1"	"1"	"1076"	"115.0"	"6.48"	"370.30"	""	"1"	""	""	""	""	"Pf00023, Pf12796"	"283373"	"ENSG00000139645"	"ANKRD52"	"A6NE79; B1Q2K2; hsa:283373; Q8NB46"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P15336"	"Cyclic AMP-dependent transcription factor ATF-2 OS=Homo sapiens OX=9606 GN=ATF2 PE=1 SV=4"	"0.000"	""	"3"	"1"	"1"	"1"	"505"	"54.5"	"7.88"	"367.30"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00170"	"1386"	"ENSG00000115966"	"ATF2"	"A1L3Z2; A4D7U4; A4D7U5; A4D7V1; D3DPE9; G8JLM5; hsa:1386; P15336; Q13000; Q3B7B7; Q4ZFU9; Q53RY2; Q8TAR1; Q96JT8"	"Estrogen-dependent gene expression; HATs acetylate histones; NGF-stimulated transcription; Heme signaling; Regulation of PTEN gene transcription; TP53 Regulates Transcription of DNA Repair Genes; Circadian Clock; Transcriptional activation of mitochondrial biogenesis; Activation of the AP-1 family of transcription factors; Response of EIF2AK4 (GCN2) to amino acid deficiency"	"Energy metabolism; IL-1 signaling pathway; B cell receptor signaling pathway; AGE/RAGE pathway; ATM signaling pathway; Interleukin-1 (IL-1) structural pathway; Myometrial relaxation and contraction pathways; MAPK signaling pathway; ATM signaling in development and disease ; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; IL-4 signaling pathway; DNA IR-double strand breaks and cellular response via ATM; Ethanol effects on histone modifications; p38 MAPK signaling pathway; PI3K-Akt signaling pathway; Thermogenesis; Gastrin signaling pathway; Hepatitis B infection; Thyroid hormones production and peripheral downstream signaling effects; Host-pathogen interaction of human coronaviruses - MAPK signaling; Pleural mesothelioma; 10q11.21q11.23 copy number variation syndrome; T-cell receptor signaling pathway"	"34"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60318"	"Germinal-center associated nuclear protein OS=Homo sapiens OX=9606 GN=MCM3AP PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"1980"	"218.3"	"6.39"	"358.19"	""	"1"	""	"cell organization and biogenesis;other metabolic processes;transport;developmental processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03399, Pf16766, Pf16768, Pf16769"	"8888"	"ENSG00000160294"	"MCM3AP"	"C9JL56; hsa:8888; O60318; Q2M3C1; Q6PJP6; Q9BSY5; Q9UMT4"	""	""	"0"	"0"	"10.7"	"3.1"	"9.1"	"6.3"	"6.3"	"12.0"	"7.7"	"7.1"	"5.9"	"16.6"	"39.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UET6"	"Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase OS=Homo sapiens OX=9606 GN=FTSJ1 PE=1 SV=2"	"0.000"	""	"3"	"1"	"1"	"1"	"329"	"36.1"	"5.69"	"306.02"	""	"1"	""	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf01728"	"24140"	"ENSG00000068438"	"FTSJ1"	"B2RCJ0; hsa:24140; O75670; Q9UET6"	"tRNA modification in the nucleus and cytosol"	""	"1"	"0"	"70.9"	"26.6"	"60.0"	"43.1"	"50.3"	"54.7"	"49.9"	"65.3"	"55.6"	"157.5"	"307.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92794"	"Histone acetyltransferase KAT6A OS=Homo sapiens OX=9606 GN=KAT6A PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"2004"	"224.9"	"5.68"	"303.58"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00628, Pf01853, Pf17772"	"7994"	"ENSG00000083168"	"KAT6A"	"hsa:7994; Q76L81; Q92794"	"HATs acetylate histones; Regulation of TP53 Activity through Acetylation"	"Pathways affected in adenoid cystic carcinoma"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P57076"	"Cilia- and flagella-associated protein 298 OS=Homo sapiens OX=9606 GN=CFAP298 PE=1 SV=1"	"0.000"	""	"4"	"1"	"1"	"1"	"290"	"33.2"	"7.44"	"302.59"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	""	"Pf11069"	"56683"	"ENSG00000159079"	"CFAP298"	"hsa:56683; P57076; Q53FH0"	""	"Ciliopathies"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P37837"	"Transaldolase OS=Homo sapiens OX=9606 GN=TALDO1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"1"	"1"	"337"	"37.5"	"6.81"	"300.35"	""	"1"	""	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00923"	"6888"	"ENSG00000177156"	"TALDO1"	"B2R8M2; hsa:6888; O00751; P37837; Q8WV32; Q8WZ45"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; NFE2L2 regulates pentose phosphate pathway genes; Pentose phosphate pathway; Insulin effects increased synthesis of Xylulose-5-Phosphate; TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P; TALDO1 deficiency: failed conversion of  Fru(6)P, E4P to SH7P, GA3P"	"Pentose phosphate metabolism; Cori cycle; Metabolic reprogramming in colon cancer"	"9"	"0"	"132.2"	"40.9"	"88.0"	"62.0"	"94.9"	"94.5"	"84.3"	"106.0"	"89.2"	"152.1"	"260.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86TS9"	"39S ribosomal protein L52, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL52 PE=1 SV=2"	"0.000"	""	"7"	"1"	"1"	"1"	"123"	"13.7"	"10.26"	"294.60"	""	"1"	""	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf18699"	"122704"	"ENSG00000172590"	"MRPL52"	"A6NMQ8; A8MXK5; A8MYI6; G3XCN9; hsa:122704; Q6NVH8; Q86TS9"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"90.9"	"36.1"	"111.4"	"99.7"	"111.8"	"119.6"	"79.7"	"91.1"	"57.7"	"120.9"	"243.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UQ84"	"Exonuclease 1 OS=Homo sapiens OX=9606 GN=EXO1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"846"	"94.0"	"8.31"	"293.96"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00752, Pf00867"	"9156"	"ENSG00000174371"	"EXO1"	"hsa:9156; O60545; O75214; O75466; Q5T396; Q96IJ1; Q9UG38; Q9UNW0; Q9UQ84"	"Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; Resolution of D-loop Structures through Holliday Junction Intermediates; Presynaptic phase of homologous DNA pairing and strand exchange; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"DNA repair pathways, full network; DNA mismatch repair; Primary ovarian insufficiency"	"19"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50552"	"Vasodilator-stimulated phosphoprotein OS=Homo sapiens OX=9606 GN=VASP PE=1 SV=3"	"0.000"	""	"4"	"1"	"1"	"1"	"380"	"39.8"	"8.94"	"292.92"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00568, Pf08776"	"7408"	"ENSG00000125753"	"VASP"	"B2RBT9; hsa:7408; P50552; Q6PIZ1; Q93035"	"Generation of second messenger molecules; Signaling by ROBO receptors; Cell-extracellular matrix interactions"	"Integrin-mediated cell adhesion; Focal adhesion"	"5"	"0"	"15.2"	"5.3"	"18.6"	"10.2"	"12.6"	"19.3"	"10.2"	"17.1"	"8.9"	"24.5"	"44.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86UK5"	"Limbin OS=Homo sapiens OX=9606 GN=EVC2 PE=1 SV=1"	"0.001"	""	"1"	"1"	"1"	"1"	"1308"	"147.9"	"6.96"	"287.58"	""	"1"	""	"signal transduction"	"plasma membrane;other membranes;cytoskeleton;other cell component"	""	"Pf12297"	"132884"	"ENSG00000173040"	"EVC2"	"hsa:132884; Q86UK5; Q86YT3; Q86YT4; Q8NG49"	"Activation of SMO"	"Hedgehog signaling pathway; Genes related to primary cilium development (based on CRISPR); Ciliopathies; Bardet-Biedl syndrome"	"6"	"0"	"33.0"	"10.1"	"28.6"	"23.6"	"46.6"	"31.6"	"22.3"	"38.2"	"47.3"	"196.9"	"781.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UNM6"	"26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2"	"0.001"	""	"2"	"1"	"1"	"1"	"376"	"42.9"	"5.81"	"284.84"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf01399"	"5719"	"ENSG00000185627"	"PSMD13"	"B3KT15; hsa:5719; O75831; Q53XU2; Q9UNM6; Q9UNV3"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"65"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15259"	"Nephrocystin-1 OS=Homo sapiens OX=9606 GN=NPHP1 PE=1 SV=1"	"0.001"	""	"1"	"1"	"1"	"1"	"732"	"83.2"	"5.20"	"284.23"	""	"1"	""	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00018"	"4867"	"ENSG00000144061"	"NPHP1"	"hsa:4867; O14837; O15259"	"Anchoring of the basal body to the plasma membrane"	"Joubert syndrome; Ciliopathies; NPHP1 deletion syndrome"	"4"	"0"	"16.9"	"4.2"	"7.4"	"11.5"	"11.9"	"9.7"	"9.9"	"11.8"	"6.5"	"12.6"	"22.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3B2"	"Exosome complex component CSL4 OS=Homo sapiens OX=9606 GN=EXOSC1 PE=1 SV=1"	"0.001"	""	"6"	"1"	"1"	"1"	"195"	"21.4"	"8.24"	"283.65"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity"	"Pf10447, Pf14382"	"51013"	"ENSG00000171311"	"EXOSC1"	"B2R9B3; hsa:51013; Q5JTH3; Q9Y3B2"	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	""	"6"	"0"	"27.4"	"8.4"	"25.0"	"18.1"	"23.0"	"26.1"	"14.3"	"24.9"	"24.8"	"44.8"	"99.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WVX9"	"Fatty acyl-CoA reductase 1 OS=Homo sapiens OX=9606 GN=FAR1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"1"	"1"	"515"	"59.3"	"9.17"	"282.52"	""	"1"	""	"other metabolic processes"	"other membranes;other cytoplasmic organelle"	"other molecular function"	"Pf03015, Pf07993"	"84188"	"ENSG00000197601"	"FAR1"	"D3DQW8; hsa:84188; Q5CZA3; Q8WVX9"	"Wax biosynthesis"	""	"1"	"0"	"12.6"	"6.4"	"10.7"	"9.3"	"5.0"	"7.4"	"9.4"	"12.4"	"8.0"	"19.4"	"45.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6WCQ1"	"Myosin phosphatase Rho-interacting protein OS=Homo sapiens OX=9606 GN=MPRIP PE=1 SV=3"	"0.000"	""	"1"	"1"	"1"	"1"	"1025"	"116.5"	"6.21"	"280.56"	""	"1"	""	""	"cytosol;cytoskeleton"	"cytoskeletal activity"	"Pf00169"	"23164"	"ENSG00000133030"	"MPRIP"	"hsa:23164; Q3KQZ5; Q5FB94; Q6DHW2; Q6WCQ1; Q7Z5Y2; Q8N390; Q96G40"	"Signaling by BRAF and RAF1 fusions"	"Smith-Magenis and Potocki-Lupski syndrome copy number variation"	"2"	"0"	"193.0"	"73.1"	"136.8"	"146.1"	"170.9"	"156.7"	"124.8"	"150.2"	"112.8"	"231.9"	"586.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P32322"	"Pyrroline-5-carboxylate reductase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PYCR1 PE=1 SV=2"	"0.000"	""	"3"	"1"	"1"	"1"	"319"	"33.3"	"7.61"	"280.41"	""	"1"	""	"other metabolic processes;stress response;other biological processes"	"mitochondrion"	"other molecular function"	"Pf03807, Pf14748"	"5831"	"ENSG00000183010"	"PYCR1"	"A6NFM2; B4DMU0; hsa:5831; P32322; Q6FHI4; Q96DI6; Q9HBQ4"	"Glutamate and glutamine metabolism"	"Amino acid metabolism; Metabolic reprogramming in colon cancer"	"3"	"0"	"22.4"	"6.4"	"9.6"	"13.8"	"18.5"	"14.4"	"11.8"	"17.4"	"9.0"	"17.9"	"33.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TBZ6"	"tRNA methyltransferase 10 homolog A OS=Homo sapiens OX=9606 GN=TRMT10A PE=1 SV=1"	"0.001"	""	"5"	"1"	"1"	"1"	"339"	"39.7"	"7.65"	"277.82"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;cytoskeleton;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01746"	"93587"	"ENSG00000145331"	"TRMT10A"	"B2R8X7; hsa:93587; Q8TBZ6; Q9Y2T9"	"tRNA modification in the nucleus and cytosol"	""	"1"	"0"	"15.8"	"7.7"	"10.7"	"10.6"	"8.3"	"11.4"	"11.4"	"17.0"	"12.3"	"15.2"	"27.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92616"	"eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6"	"0.001"	""	"0"	"1"	"1"	"1"	"2671"	"292.6"	"7.47"	"275.19"	""	"1"	""	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"29.3"	"7.1"	"18.0"	"20.4"	"17.1"	"17.4"	"19.9"	"22.7"	"16.9"	"39.5"	"107.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92833"	"Protein Jumonji OS=Homo sapiens OX=9606 GN=JARID2 PE=1 SV=2"	"0.001"	""	"1"	"1"	"1"	"1"	"1246"	"138.6"	"9.38"	"273.54"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01388, Pf02373, Pf02375, Pf02928"	"3720"	"ENSG00000008083"	"JARID2"	"A8K9Z6; B7Z5S5; B7Z8L0; hsa:3720; Q5U5L5; Q86X63; Q92833"	"PRC2 methylates histones and DNA"	"Endoderm differentiation; Mesodermal commitment pathway; Interactome of polycomb repressive complex 2 (PRC2) ; Orexin receptor pathway"	"5"	"0"	"40.0"	"22.1"	"37.8"	"33.1"	"32.5"	"45.5"	"37.1"	"43.9"	"49.4"	"88.2"	"157.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96SU4"	"Oxysterol-binding protein-related protein 9 OS=Homo sapiens OX=9606 GN=OSBPL9 PE=1 SV=2"	"0.001"	""	"1"	"1"	"1"	"1"	"736"	"83.1"	"6.18"	"265.85"	""	"1"	""	"other metabolic processes;transport"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00169, Pf01237"	"114883"	"ENSG00000117859"	"OSBPL9"	"B1AKJ8; B3KPQ4; D3DQ31; hsa:114883; Q5TFC0; Q6IA67; Q86YQ3; Q8NB17; Q8TAS8; Q96SK4; Q96SU4; Q9H9X2"	"Synthesis of bile acids and bile salts"	""	"1"	"0"	"18.0"	"13.3"	"15.5"	"16.2"	"15.5"	"23.4"	"17.5"	"21.9"	"17.8"	"29.2"	"42.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H4X1"	"Regulator of cell cycle RGCC OS=Homo sapiens OX=9606 GN=RGCC PE=1 SV=1"	"0.001"	""	"8"	"1"	"1"	"1"	"137"	"14.6"	"4.75"	"265.12"	""	"1"	""	"cell cycle OR cell proliferation;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf15151"	"28984"	"ENSG00000102760"	"RGCC"	"hsa:28984; Q6NZ48; Q9H4X1; Q9UL69"	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96IZ5"	"RNA-binding protein 41 OS=Homo sapiens OX=9606 GN=RBM41 PE=1 SV=2"	"0.001"	""	"3"	"1"	"1"	"1"	"413"	"47.1"	"8.70"	"256.96"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"55285"	"ENSG00000089682"	"RBM41"	"hsa:55285; Q5JSN7; Q5JSN8; Q96IZ5; Q9H8F7; Q9NV04"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NRG0"	"Chromatin accessibility complex protein 1 OS=Homo sapiens OX=9606 GN=CHRAC1 PE=1 SV=1"	"0.001"	""	"6"	"1"	"1"	"1"	"131"	"14.7"	"5.10"	"256.59"	""	"1"	""	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00808"	"54108"	"ENSG00000104472"	"CHRAC1"	"hsa:54108; Q9NRG0"	""	"Acute viral myocarditis"	"1"	"0"	"96.8"	"49.2"	"78.8"	"64.9"	"71.5"	"91.1"	"80.3"	"74.3"	"72.4"	"88.0"	"177.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14247"	"Src substrate cortactin OS=Homo sapiens OX=9606 GN=CTTN PE=1 SV=2"	"0.001"	""	"1"	"1"	"1"	"1"	"550"	"61.5"	"5.40"	"255.62"	""	"1"	""	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf02218, Pf14604"	"2017"	"ENSG00000085733; ENSG00000288401"	"CTTN"	"hsa:2017; Q14247; Q8N707; Q96H99"	"Clathrin-mediated endocytosis; RHO GTPases activate PAKs"	"Pathogenic Escherichia coli infection; Hepatitis C and hepatocellular carcinoma"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96K17"	"Transcription factor BTF3 homolog 4 OS=Homo sapiens OX=9606 GN=BTF3L4 PE=1 SV=1"	"0.001"	""	"4"	"1"	"1"	"1"	"158"	"17.3"	"6.35"	"253.80"	""	"1"	""	""	""	""	"Pf01849"	"91408"	"ENSG00000134717"	"BTF3L4"	"B3KNJ1; D3DQ32; G3V1C6; hsa:91408; Q96K17"	""	""	"0"	"0"	"101.5"	"38.4"	"92.2"	"85.5"	"90.1"	"171.7"	"184.7"	"303.3"	"211.8"	"216.8"	"352.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L1Q6"	"Basic leucine zipper and W2 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=BZW1 PE=1 SV=1"	"0.001"	""	"1"	"1"	"1"	"1"	"419"	"48.0"	"5.92"	"252.37"	""	"1"	""	"other biological processes"	"other cell component"	""	"Pf02020"	"9689"	"ENSG00000082153"	"BZW1"	"B4DLZ8; B4DWF7; hsa:9689; Q14281; Q15394; Q7L1Q6; Q9BUY0"	""	""	"0"	"0"	"49.7"	"23.6"	"33.7"	"31.9"	"44.1"	"55.3"	"53.6"	"56.2"	"42.3"	"51.8"	"68.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBI6"	"Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 OS=Homo sapiens OX=9606 GN=GNG12 PE=1 SV=3"	"0.001"	""	"10"	"1"	"1"	"1"	"72"	"8.0"	"8.97"	"251.88"	""	"1"	""	"signal transduction"	"plasma membrane;other membranes"	"other molecular function"	"Pf00631"	"55970"	"ENSG00000172380"	"GNG12"	"hsa:55970; Q69YP5; Q9BRV5; Q9UBI6"	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Ca2+ pathway; G alpha (12/13) signalling events; G alpha (q) signalling events; G alpha (i) signalling events; G alpha (z) signalling events; ADP signalling through P2Y purinoceptor 12; Extra-nuclear estrogen signaling; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; Thrombin signalling through proteinase activated receptors (PARs); Activation of G protein gated Potassium channels; G-protein activation; G beta:gamma signalling through PI3Kgamma; Prostacyclin signalling through prostacyclin receptor; Adrenaline,noradrenaline inhibits insulin secretion; G beta:gamma signalling through PLC beta; ADP signalling through P2Y purinoceptor 1; Glucagon-type ligand receptors; Thromboxane signalling through TP receptor; Vasopressin regulates renal water homeostasis via Aquaporins; Presynaptic function of Kainate receptors; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; G beta:gamma signalling through BTK; G beta:gamma signalling through CDC42; Inhibition  of voltage gated Ca2+ channels via Gbeta/gamma subunits; Glucagon signaling in metabolic regulation"	"Myometrial relaxation and contraction pathways; G protein signaling pathways; MAPK signaling pathway; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Ras signaling; Regulation of actin cytoskeleton; Calcium regulation in cardiac cells"	"37"	"0"	"245.0"	"103.6"	"157.7"	"113.8"	"150.8"	"158.8"	"125.8"	"176.1"	"157.7"	"289.4"	"428.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60343"	"TBC1 domain family member 4 OS=Homo sapiens OX=9606 GN=TBC1D4 PE=1 SV=2"	"0.001"	""	"0"	"1"	"1"	"1"	"1298"	"146.5"	"7.01"	"251.76"	""	"1"	""	"transport;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity"	"Pf00566, Pf00640, Pf11830"	"9882"	"ENSG00000136111"	"TBC1D4"	"A7E2X8; B4DU25; B4E235; B6ETN8; B6ETN9; hsa:9882; O60343; Q5W0B9; Q68D14"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"	"Ciliary landscape; Thyroid hormones production and peripheral downstream signaling effects; Insulin signaling"	"4"	"0"	"95.6"	"37.1"	"82.0"	"71.4"	"86.2"	"94.2"	"67.9"	"85.1"	"68.1"	"132.3"	"211.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q1ED39"	"Lysine-rich nucleolar protein 1 OS=Homo sapiens OX=9606 GN=KNOP1 PE=1 SV=1"	"0.001"	""	"2"	"1"	"1"	"1"	"458"	"51.6"	"9.86"	"251.68"	""	"1"	""	""	"nucleus"	""	"Pf15477"	"400506"	"ENSG00000103550"	"KNOP1"	"hsa:400506; O43328; Q1ED39; Q5FWF3"	""	""	"0"	"0"	"138.8"	"68.6"	"135.0"	"123.7"	"129.5"	"166.3"	"115.5"	"169.5"	"113.9"	"320.0"	"587.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9C099"	"Leucine-rich repeat and coiled-coil domain-containing protein 1 OS=Homo sapiens OX=9606 GN=LRRCC1 PE=1 SV=2"	"0.001"	""	"1"	"1"	"1"	"1"	"1032"	"119.5"	"5.88"	"250.75"	""	"1"	""	"cell cycle OR cell proliferation;other biological processes"	"cytoskeleton;other cell component"	""	""	"85444"	"ENSG00000133739"	"LRRCC1"	"B4DYX6; B5RI11; hsa:85444; Q8N768; Q96DK7; Q96N01; Q9C099"	""	""	"0"	"0"	"461.1"	"224.3"	"388.3"	"384.1"	"395.7"	"448.9"	"338.6"	"454.9"	"307.2"	"512.6"	"859.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H814"	"Phosphorylated adapter RNA export protein OS=Homo sapiens OX=9606 GN=PHAX PE=1 SV=1"	"0.001"	""	"3"	"1"	"1"	"1"	"394"	"44.4"	"5.40"	"250.40"	""	"1"	""	"transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf10258"	"51808"	"ENSG00000164902"	"PHAX"	"hsa:51808; Q9H814; Q9H8W1"	"RNA polymerase II transcribes snRNA genes; snRNP Assembly"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15435"	"Protein phosphatase 1 regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PPP1R7 PE=1 SV=1"	"0.001"	""	"3"	"1"	"1"	"1"	"360"	"41.5"	"4.91"	"248.84"	""	"1"	""	"other biological processes"	"other cell component"	"enzyme regulator activity"	"Pf14580"	"5510"	"ENSG00000115685"	"PPP1R7"	"B4DFD4; B5MCY6; hsa:5510; Q15435; Q9UQE5; Q9UQE6; Q9Y6K4"	""	"2q37 copy number variation syndrome"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q53FA7"	"Quinone oxidoreductase PIG3 OS=Homo sapiens OX=9606 GN=TP53I3 PE=1 SV=2"	"0.001"	""	"2"	"1"	"1"	"1"	"332"	"35.5"	"7.17"	"246.80"	""	"1"	""	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00107, Pf08240"	"9540"	"ENSG00000115129"	"TP53I3"	"D6W533; hsa:9540; O14679; O14685; Q38G78; Q53FA7; Q6JLE7; Q9BWB8"	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"	"p53 transcriptional gene network; SARS-CoV-2 innate immunity evasion and cell-specific immune response"	"3"	"0"	"16.6"	"4.4"	"17.8"	"10.5"	"13.2"	"17.3"	"15.4"	"38.3"	"62.8"	"159.2"	"279.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N9R8"	"Protein SCAI OS=Homo sapiens OX=9606 GN=SCAI PE=1 SV=2"	"0.001"	""	"2"	"1"	"1"	"1"	"606"	"70.4"	"8.60"	"246.57"	""	"1"	""	"other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf12070"	"286205"	"ENSG00000173611"	"SCAI"	"hsa:286205; Q3SXZ1; Q3SXZ2; Q5T163; Q8N1I4; Q8N9R8"	"RHO GTPases Activate Formins"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99698"	"Lysosomal-trafficking regulator OS=Homo sapiens OX=9606 GN=LYST PE=1 SV=3"	"0.001"	""	"0"	"1"	"1"	"1"	"3801"	"428.9"	"6.61"	"245.96"	""	"1"	""	"cell organization and biogenesis;stress response;transport;other biological processes"	"other membranes;cytosol;cytoskeleton"	"other molecular function"	"Pf00400, Pf02138, Pf14844"	"1130"	"ENSG00000143669"	"LYST"	"hsa:1130; O43274; Q5T2U9; Q96TD7; Q96TD8; Q99698; Q99709; Q9H133"	""	""	"0"	"0"	"199.0"	"61.6"	"129.6"	"106.6"	"110.0"	"139.7"	"144.1"	"237.9"	"180.3"	"250.1"	"508.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60762"	"Dolichol-phosphate mannosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=DPM1 PE=1 SV=1"	"0.001"	""	"3"	"1"	"1"	"1"	"260"	"29.6"	"9.57"	"245.22"	""	"1"	""	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf00535"	"8813"	"ENSG00000000419"	"DPM1"	"hsa:8813; O15157; O60762; Q6IB78; Q96HK0"	"Synthesis of dolichyl-phosphate mannose; Defective DPM1 causes DPM1-CDG; Defective DPM3 causes DPM3-CDG; Defective DPM2 causes DPM2-CDG"	"VEGFA-VEGFR2 signaling; N-glycan biosynthesis"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P06280"	"Alpha-galactosidase A OS=Homo sapiens OX=9606 GN=GLA PE=1 SV=1"	"0.001"	""	"3"	"1"	"1"	"1"	"429"	"48.7"	"5.60"	"245.15"	""	"1"	""	"other metabolic processes;other biological processes"	"non-structural extracellular;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf16499, Pf17450"	"2717"	"ENSG00000102393"	"GLA"	"hsa:2717; P06280; Q6LER7"	"Neutrophil degranulation; Glycosphingolipid metabolism"	"Degradation pathway of sphingolipids, including diseases; Ciliary landscape"	"4"	"0"	"9.6"	"11.9"	"8.9"	"6.7"	"11.3"	"7.0"	"5.2"	"8.5"	"9.7"	"11.2"	"23.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A6NCE7"	"Microtubule-associated proteins 1A/1B light chain 3 beta 2 OS=Homo sapiens OX=9606 GN=MAP1LC3B2 PE=2 SV=1"	"0.001"	""	"6"	"1"	"1"	"1"	"125"	"14.6"	"8.68"	"244.27"	""	"1"	""	"cell organization and biogenesis;other metabolic processes;stress response"	"other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02991"	"643246"	"ENSG00000258102"	"MAP1LC3B2"	"A6NCE7; hsa:643246"	""	""	"0"	"0"	"72.0"	"38.7"	"71.3"	"51.2"	"68.3"	"78.6"	"62.8"	"79.2"	"61.1"	"192.4"	"480.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60941"	"Dystrobrevin beta OS=Homo sapiens OX=9606 GN=DTNB PE=1 SV=1"	"0.001"	""	"2"	"1"	"1"	"1"	"627"	"71.3"	"7.91"	"242.79"	""	"1"	""	"cell-cell signaling;developmental processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00569, Pf09068, Pf09069"	"1838"	"ENSG00000138101"	"DTNB"	"B7Z733; F5GZG4; G5E9F6; hsa:1838; O43782; O60881; O60941; O75538; Q86VR4; Q96AW0; Q9UE14; Q9UE15; Q9UE16"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00151"	"PDZ and LIM domain protein 1 OS=Homo sapiens OX=9606 GN=PDLIM1 PE=1 SV=4"	"0.001"	""	"3"	"1"	"1"	"1"	"329"	"36.0"	"7.02"	"242.55"	""	"1"	""	"cell organization and biogenesis;stress response;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412, Pf00595, Pf15936"	"9124"	"ENSG00000107438"	"PDLIM1"	"B2RBS6; hsa:9124; O00151; Q5VZH5; Q9BPZ9"	""	""	"0"	"0"	"185.9"	"80.6"	"129.0"	"130.2"	"151.6"	"148.2"	"135.2"	"158.1"	"134.3"	"186.5"	"340.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NPJ8"	"NTF2-related export protein 2 OS=Homo sapiens OX=9606 GN=NXT2 PE=1 SV=1"	"0.001"	""	"5"	"1"	"1"	"1"	"142"	"16.2"	"5.48"	"242.02"	""	"1"	""	"other metabolic processes;transport"	"cytosol;nucleus;other cell component"	""	"Pf02136"	"55916"	"ENSG00000101888"	"NXT2"	"D3DUY1; hsa:55916; Q0VAN8; Q5JYV5; Q5JYV6; Q5JYV7; Q9H8U0; Q9NPJ8; Q9NQ64; Q9NRL7; Q9Y3M4; Q9Y3M5"	""	""	"0"	"0"	"88.0"	"36.2"	"61.7"	"62.7"	"62.9"	"82.5"	"60.4"	"92.3"	"77.4"	"130.2"	"138.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35227"	"Polycomb group RING finger protein 2 OS=Homo sapiens OX=9606 GN=PCGF2 PE=1 SV=1"	"0.001"	""	"2"	"1"	"1"	"1"	"344"	"37.8"	"7.96"	"241.07"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13923, Pf16207"	"7703"	"ENSG00000277258; ENSG00000278644"	"PCGF2"	"A6NGD8; hsa:7703; P35227"	"SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Activation of anterior HOX genes in hindbrain development during early embryogenesis; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; Transcriptional Regulation by E2F6"	"17q12 copy number variation syndrome"	"8"	"0"	"187.6"	"91.4"	"187.4"	"173.8"	"174.7"	"281.2"	"310.8"	"458.9"	"324.8"	"324.7"	"607.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WYH8"	"Inhibitor of growth protein 5 OS=Homo sapiens OX=9606 GN=ING5 PE=1 SV=1"	"0.001"	""	"7"	"1"	"1"	"1"	"240"	"27.7"	"7.61"	"239.86"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf12998"	"84289"	"ENSG00000168395"	"ING5"	"A8K1P3; hsa:84289; Q53NU6; Q57Z54; Q8WYH8; Q9BS30"	"HATs acetylate histones; Regulation of TP53 Activity through Acetylation"	"2q37 copy number variation syndrome"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NW82"	"WD repeat-containing protein 70 OS=Homo sapiens OX=9606 GN=WDR70 PE=1 SV=1"	"0.001"	""	"2"	"1"	"1"	"1"	"654"	"73.2"	"6.33"	"239.43"	""	"1"	""	""	"nucleus;other cell component"	"other molecular function"	"Pf00400"	"55100"	"ENSG00000082068"	"WDR70"	"hsa:55100; Q9H053; Q9NW82"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IWC1"	"MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2"	"0.001"	""	"1"	"1"	"1"	"1"	"876"	"98.4"	"9.32"	"238.82"	""	"1"	""	"cell organization and biogenesis"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf05672"	"79649"	"ENSG00000129680"	"MAP7D3"	"A2A2J0; A6NCZ7; A6NHR4; B4DWD2; H7BY77; hsa:79649; Q5JXI5; Q5JXI6; Q6P2S1; Q8IWC1; Q9H9M8"	""	""	"0"	"0"	"43.3"	"21.1"	"36.4"	"39.5"	"43.9"	"49.6"	"35.0"	"44.7"	"21.3"	"618.0"	"2724.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13217"	"DnaJ homolog subfamily C member 3 OS=Homo sapiens OX=9606 GN=DNAJC3 PE=1 SV=1"	"0.001"	""	"1"	"1"	"1"	"1"	"504"	"57.5"	"6.15"	"237.56"	""	"1"	""	"protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00226, Pf00515, Pf13181, Pf13432"	"5611"	"ENSG00000102580"	"DNAJC3"	"hsa:5611; Q13217; Q86WT9; Q8N4N2"	"Neutrophil degranulation; Viral mRNA Translation; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; XBP1(S) activates chaperone genes"	"Photodynamic therapy-induced unfolded protein response"	"6"	"0"	"85.3"	"45.4"	"78.1"	"76.4"	"86.7"	"97.9"	"66.3"	"90.5"	"67.7"	"264.3"	"592.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14188"	"Transcription factor Dp-2 OS=Homo sapiens OX=9606 GN=TFDP2 PE=1 SV=2"	"0.001"	""	"4"	"1"	"1"	"1"	"446"	"49.2"	"6.57"	"235.14"	""	"1"	""	"cell cycle OR cell proliferation;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02319, Pf08781"	"7029"	"ENSG00000114126"	"TFDP2"	"B7Z8C8; B7Z8L5; D3DNG1; E9PFC3; F8WAI2; hsa:7029; Q13331; Q14187; Q14188; Q6R754; Q8WU88; Q9UG28"	"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; G1/S-Specific Transcription; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1; Cyclin D associated events in G1; SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Oxidative Stress Induced Senescence; Oncogene Induced Senescence; Pre-NOTCH Transcription and Translation; Transcriptional Regulation by E2F6; Defective binding of RB1 mutants to E2F1,(E2F2, E2F3); Activation of PUMA and translocation to mitochondria; Transcriptional regulation of granulopoiesis; Cyclin E associated events during G1/S transition ; Transcription of E2F targets under negative control by DREAM complex; Cyclin A:Cdk2-associated events at S phase entry; Activation of NOXA and translocation to mitochondria; Inhibition of replication initiation of damaged DNA by RB1/E2F1"	"Cell cycle; Retinoblastoma gene in cancer; G1 to S cell cycle control; DYRK1A involvement regarding cell proliferation in brain development; Alstrom syndrome"	"23"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96LT9"	"RNA-binding region-containing protein 3 OS=Homo sapiens OX=9606 GN=RNPC3 PE=1 SV=1"	"0.001"	""	"3"	"1"	"1"	"1"	"517"	"58.5"	"7.72"	"235.05"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"55599"	"ENSG00000185946"	"RNPC3"	"A8K1C9; D3DT74; hsa:55599; Q5TZ87; Q96FK7; Q96JI8; Q96LT9; Q9NSU7; Q9NXX2"	"mRNA Splicing - Minor Pathway"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q93008"	"Probable ubiquitin carboxyl-terminal hydrolase FAF-X OS=Homo sapiens OX=9606 GN=USP9X PE=1 SV=3"	"0.001"	""	"0"	"1"	"1"	"1"	"2570"	"292.1"	"5.80"	"234.48"	""	"1"	""	"protein metabolism;other metabolic processes"	""	"other molecular function"	"Pf00443, Pf12030"	"100971796; 465582"	"ENSPPAG00000039671; ENSPTRG00000045541"	"USP9X"	"A0A2I3RAB4; A0A2J8JDU7; A0A2R9BVD0; A0A6D2WW26"	""	""	"0"	"0"	"208.3"	"133.0"	"248.8"	"233.0"	"194.7"	"294.3"	"199.6"	"250.6"	"171.3"	"283.0"	"455.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00487"	"26S proteasome non-ATPase regulatory subunit 14 OS=Homo sapiens OX=9606 GN=PSMD14 PE=1 SV=1"	"0.001"	""	"2"	"1"	"1"	"1"	"310"	"34.6"	"6.52"	"234.47"	""	"1"	""	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01398, Pf13012"	"10213"	"ENSG00000115233"	"PSMD14"	"B3KNW2; hsa:10213; O00176; O00487"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Metalloprotease DUBs"	"Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"64"	"0"	"94.4"	"49.3"	"68.9"	"58.2"	"67.7"	"85.2"	"61.0"	"74.1"	"76.0"	"116.7"	"254.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A6NKF1"	"SAC3 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SAC3D1 PE=1 SV=2"	"0.001"	""	"1"	"1"	"1"	"1"	"404"	"43.5"	"8.69"	"233.86"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus;other cell component"	""	"Pf03399"	""	""	"SAC3D1"	"A6NKF1; A8MX08; Q99773"	""	""	"0"	"0"	"33.1"	"13.9"	"36.1"	"24.6"	"32.9"	"35.9"	"24.1"	"32.4"	"27.1"	"56.5"	"77.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35613"	"Basigin OS=Homo sapiens OX=9606 GN=BSG PE=1 SV=2"	"0.001"	""	"2"	"1"	"1"	"1"	"385"	"42.2"	"5.66"	"233.79"	""	"1"	""	"developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf13927"	"682"	"ENSG00000172270"	"BSG"	"A6NJW1; D3YLG5; hsa:682; P35613; Q7Z796; Q8IZL7"	"Degradation of the extracellular matrix; Integrin cell surface interactions; Pyruvate metabolism; Aspirin ADME; Basigin interactions; Proton-coupled monocarboxylate transport; Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT)"	"Matrix metalloproteinases; VEGFA-VEGFR2 signaling; IL-18 signaling pathway"	"10"	"0"	"335.0"	"100.0"	"153.9"	"88.0"	"169.3"	"135.9"	"149.8"	"216.4"	"221.7"	"415.3"	"783.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60313"	"Dynamin-like 120 kDa protein, mitochondrial OS=Homo sapiens OX=9606 GN=OPA1 PE=1 SV=3"	"0.001"	""	"1"	"1"	"1"	"1"	"960"	"111.6"	"7.87"	"233.45"	""	"1"	""	"cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00350, Pf19434"	"4976"	"ENSG00000198836"	"OPA1"	"D3DNW4; E5KLJ5; E5KLJ6; E5KLJ7; E5KLK1; E5KLK2; hsa:4976; O60313"	"Regulation of Apoptosis"	"Orexin receptor pathway"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H3P7"	"Golgi resident protein GCP60 OS=Homo sapiens OX=9606 GN=ACBD3 PE=1 SV=4"	"0.001"	""	"1"	"1"	"1"	"1"	"528"	"60.6"	"5.06"	"232.96"	""	"1"	""	"other metabolic processes"	"other membranes;mitochondrion;ER/Golgi"	"other molecular function"	"Pf00887, Pf13897"	"64746"	"ENSG00000182827"	"ACBD3"	"B2RB29; hsa:64746; Q5VTJ0; Q6P9F1; Q8IZC5; Q8N4D6; Q9H3P7; Q9H6U3"	"Golgi Associated Vesicle Biogenesis"	""	"1"	"0"	"52.8"	"21.6"	"25.0"	"25.9"	"33.2"	"51.2"	"47.0"	"66.4"	"53.6"	"69.2"	"153.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15024"	"Exosome complex component RRP42 OS=Homo sapiens OX=9606 GN=EXOSC7 PE=1 SV=3"	"0.001"	""	"2"	"1"	"1"	"1"	"291"	"31.8"	"5.19"	"232.94"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01138, Pf03725"	"23016"	"ENSG00000075914"	"EXOSC7"	"hsa:23016; Q15024; Q96E72"	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	"Ciliary landscape"	"7"	"0"	"59.7"	"30.4"	"55.4"	"67.5"	"64.0"	"79.2"	"59.0"	"66.2"	"47.8"	"104.0"	"193.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8ND61"	"Uncharacterized protein C3orf20 OS=Homo sapiens OX=9606 GN=C3orf20 PE=2 SV=2"	"0.001"	""	"1"	"1"	"1"	"1"	"904"	"101.2"	"9.13"	"232.81"	""	"1"	""	""	"other membranes;other cell component"	""	"Pf14977"	"84077"	"ENSG00000131379"	"C3orf20"	"hsa:84077; Q7L0U6; Q8NCP2; Q8ND61; Q9H0I7"	""	""	"0"	"0"	"263.9"	"124.0"	"221.3"	"212.5"	"216.9"	"238.6"	"221.3"	"255.4"	"215.1"	"313.8"	"500.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15067"	"Peroxisomal acyl-coenzyme A oxidase 1 OS=Homo sapiens OX=9606 GN=ACOX1 PE=1 SV=3"	"0.001"	""	"1"	"1"	"1"	"1"	"660"	"74.4"	"8.16"	"232.66"	""	"1"	""	"cell organization and biogenesis;other metabolic processes;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle"	"other molecular function"	"Pf01756, Pf02770, Pf14749"	"51"	"ENSG00000161533"	"ACOX1"	"A8K6X8; A8KAA0; B4DK61; F5GYQ8; hsa:51; Q12863; Q15067; Q15068; Q15101; Q16131; Q7Z3W5; Q9UD31"	"TYSND1 cleaves peroxisomal proteins"	"Estrogen receptor pathway; Nuclear receptors meta-pathway; PPAR signaling pathway; Eicosanoid metabolism via cyclooxygenases (COX); Eicosanoid metabolism via lipooxygenases (LOX); Omega-3 / omega-6 fatty acid synthesis"	"8"	"0"	"45.9"	"19.2"	"48.4"	"37.8"	"43.2"	"56.2"	"41.0"	"50.0"	"28.4"	"101.4"	"380.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16637"	"Survival motor neuron protein OS=Homo sapiens OX=9606 GN=SMN1 PE=1 SV=1"	"0.001"	""	"2"	"1"	"1"	"1"	"294"	"31.8"	"6.55"	"232.55"	""	"1"	""	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06003"	"6606; 6607"	"ENSG00000172062; ENSG00000205571; ENSG00000273772; ENSG00000275349; ENSG00000277773"	"SMN1; SMN2"	"A8K0V4; hsa:6606; hsa:6607; Q13119; Q16637; Q549U5; Q96J51"	"snRNP Assembly; SARS-CoV-2 modulates host translation machinery"	""	"2"	"0"	"135.8"	"72.5"	"107.3"	"100.4"	"115.3"	"139.8"	"97.4"	"131.9"	"108.4"	"200.0"	"350.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94986"	"Centrosomal protein of 152 kDa OS=Homo sapiens OX=9606 GN=CEP152 PE=1 SV=4"	"0.001"	""	"0"	"1"	"1"	"1"	"1710"	"195.5"	"5.60"	"232.19"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	""	"22995"	"ENSG00000103995"	"CEP152"	"E7ER66; hsa:22995; O94986; Q17RV1; Q6NTA0"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	""	"7"	"0"	"163.6"	"87.3"	"157.6"	"165.9"	"173.4"	"187.2"	"154.1"	"192.4"	"119.7"	"222.7"	"375.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5T200"	"Zinc finger CCCH domain-containing protein 13 OS=Homo sapiens OX=9606 GN=ZC3H13 PE=1 SV=1"	"0.001"	""	"1"	"1"	"1"	"1"	"1668"	"196.5"	"9.42"	"231.63"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00642"	"23091"	"ENSG00000123200"	"ZC3H13"	"A2A323; hsa:23091; O94936; Q5T1Z9; Q5T200; Q7Z7J3; Q8NDT6; Q9H0L6"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P38935"	"DNA-binding protein SMUBP-2 OS=Homo sapiens OX=9606 GN=IGHMBP2 PE=1 SV=3"	"0.001"	""	"1"	"1"	"1"	"1"	"993"	"109.1"	"8.97"	"231.60"	""	"1"	""	"cell organization and biogenesis;RNA metabolism OR transcription"	"nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf01424, Pf01428, Pf13086, Pf13087"	"3508"	"ENSG00000132740"	"IGHMBP2"	"A0PJD2; hsa:3508; P38935; Q00443; Q14177"	""	""	"0"	"0"	"189.0"	"92.6"	"160.5"	"139.1"	"166.2"	"182.9"	"140.3"	"218.3"	"195.1"	"774.8"	"1828.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H6Y2"	"WD repeat-containing protein 55 OS=Homo sapiens OX=9606 GN=WDR55 PE=1 SV=2"	"0.001"	""	"2"	"1"	"1"	"1"	"383"	"42.0"	"4.92"	"231.54"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf00400, Pf12894"	"54853"	"ENSG00000120314"	"WDR55"	"hsa:54853; Q9H6Y2; Q9NXK4"	""	""	"0"	"0"	"129.8"	"76.5"	"130.9"	"111.7"	"136.4"	"162.6"	"114.6"	"182.9"	"110.7"	"226.6"	"330.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z2T5"	"TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2"	"0.002"	""	"1"	"1"	"1"	"1"	"733"	"81.7"	"7.88"	"231.18"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf02005"	"81627"	"ENSG00000121486"	"TRMT1L"	"hsa:81627; Q5TEN0; Q6ZMX0; Q7Z2T5; Q8IWH5; Q8NC68; Q9BZQ1"	""	""	"0"	"0"	"195.9"	"72.1"	"172.7"	"147.0"	"158.6"	"208.1"	"128.8"	"175.2"	"128.8"	"242.4"	"321.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H939"	"Proline-serine-threonine phosphatase-interacting protein 2 OS=Homo sapiens OX=9606 GN=PSTPIP2 PE=1 SV=4"	"0.002"	""	"4"	"1"	"1"	"1"	"334"	"38.8"	"8.48"	"231.15"	""	"1"	""	"cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00611"	"9050"	"ENSG00000152229"	"PSTPIP2"	"hsa:9050; Q9H939"	""	""	"0"	"0"	"10.5"	"3.4"	"8.0"	"9.1"	"8.7"	"12.1"	"8.4"	"14.5"	"13.5"	"32.4"	"26.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6ZU35"	"Capping protein inhibiting regulator of actin dynamics OS=Homo sapiens OX=9606 GN=CRACD PE=1 SV=3"	"0.002"	""	"1"	"1"	"1"	"1"	"1233"	"136.7"	"5.60"	"230.98"	""	"1"	""	"cell organization and biogenesis;other biological processes"	"cytosol"	""	"Pf15262"	"57482"	"ENSG00000109265"	"CRACD"	"hsa:57482; Q6ZU35; Q9NTE2; Q9NTP8; Q9ULK9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13042"	"Cell division cycle protein 16 homolog OS=Homo sapiens OX=9606 GN=CDC16 PE=1 SV=2"	"0.002"	""	"1"	"1"	"1"	"1"	"620"	"71.6"	"5.85"	"230.79"	""	"1"	""	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf12895, Pf13424"	"8881"	"ENSG00000130177"	"CDC16"	"A2A365; hsa:8881; Q13042; Q5T8C8; Q7Z651; Q96AE6; Q9Y564"	"Assembly of the pre-replicative complex; Separation of Sister Chromatids; Antigen processing: Ubiquitination & Proteasome degradation; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; CDK-mediated phosphorylation and removal of Cdc6; Autodegradation of Cdh1 by Cdh1:APC/C; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of Cyclin B; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; Regulation of APC/C activators between G1/S and early anaphase; Phosphorylation of the APC/C; APC-Cdc20 mediated degradation of Nek2A; Senescence-Associated Secretory Phenotype (SASP); Transcriptional Regulation by VENTX; Aberrant regulation of mitotic exit in cancer due to RB1 defects"	"Cell cycle"	"19"	"0"	"103.6"	"50.3"	"108.3"	"88.0"	"79.2"	"109.6"	"71.4"	"107.9"	"79.2"	"153.6"	"291.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6PK04"	"Coiled-coil domain-containing protein 137 OS=Homo sapiens OX=9606 GN=CCDC137 PE=1 SV=1"	"0.002"	""	"5"	"1"	"1"	"1"	"289"	"33.2"	"10.93"	"230.71"	""	"1"	""	""	"nucleus;other cell component"	""	""	"339230"	"ENSG00000185298"	"CCDC137"	"hsa:339230; Q6PK04"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UH92"	"Max-like protein X OS=Homo sapiens OX=9606 GN=MLX PE=1 SV=2"	"0.002"	""	"2"	"1"	"1"	"1"	"298"	"33.3"	"8.06"	"230.48"	""	"1"	""	"other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00010"	"6945"	"ENSG00000108788"	"MLX"	"A8K2J3; B2RAV8; B2RD73; hsa:6945; Q53XM6; Q96FL2; Q9H2V0; Q9H2V1; Q9H2V2; Q9NXN3; Q9UH92"	"ChREBP activates metabolic gene expression"	"Nonalcoholic fatty liver disease"	"2"	"0"	"74.8"	"34.4"	"33.4"	"82.5"	"51.9"	"55.0"	"60.2"	"375.6"	"89.3"	"460.6"	"79.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IXI1"	"Mitochondrial Rho GTPase 2 OS=Homo sapiens OX=9606 GN=RHOT2 PE=1 SV=2"	"0.002"	""	"2"	"1"	"1"	"1"	"618"	"68.1"	"5.86"	"230.39"	""	"1"	""	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf00071, Pf08355, Pf08356"	"89941"	"ENSG00000140983"	"RHOT2"	"A2IDC2; hsa:89941; Q8IXI1; Q8NF53; Q96C13; Q96S17; Q9BT60; Q9H7M8"	"RHOT2 GTPase cycle"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5U5X0"	"Complex III assembly factor LYRM7 OS=Homo sapiens OX=9606 GN=LYRM7 PE=1 SV=1"	"0.002"	""	"6"	"1"	"1"	"1"	"104"	"11.9"	"9.66"	"230.36"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf05347"	"90624"	"ENSG00000186687"	"LYRM7"	"A8MPQ9; hsa:90624; Q5U5X0; Q86Y68"	""	"Mitochondrial complex III assembly"	"1"	"0"	"85.2"	"38.0"	"66.4"	"68.4"	"72.4"	"87.9"	"75.2"	"115.3"	"87.8"	"131.0"	"247.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NW13"	"RNA-binding protein 28 OS=Homo sapiens OX=9606 GN=RBM28 PE=1 SV=3"	"0.002"	""	"2"	"1"	"1"	"1"	"759"	"85.7"	"9.22"	"229.47"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf00076"	"55131"	"ENSG00000106344"	"RBM28"	"A4D100; B4DU52; E9PDD9; hsa:55131; Q53H65; Q96CV3; Q9NW13"	"Major pathway of rRNA processing in the nucleolus and cytosol"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86UQ4"	"ATP-binding cassette sub-family A member 13 OS=Homo sapiens OX=9606 GN=ABCA13 PE=2 SV=3"	"0.002"	""	"0"	"1"	"1"	"1"	"5058"	"575.8"	"6.46"	"229.13"	""	"1"	""	"transport;other biological processes"	"plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00005, Pf12698"	"154664"	"ENSG00000179869"	"ABCA13"	"hsa:154664; K9LC76; K9LC79; K9LCX7; K9LDK8; K9LDY4; Q6ZTT7; Q86UQ4; Q86WI2; Q8N248"	"Neutrophil degranulation"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""